Compounds > irinotecan
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irinotecan and Lupus Nephritis

irinotecan has been researched along with Lupus Nephritis in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anders, HJ; Frese, S; Frese-Schaper, M; Gugger, M; Huynh-Do, U; Keil, A; Kocher, GJ; Körner, M; Schiffer, L; Schmid, RA; Steiner, SK1
Frese, S; Frese-Schaper, M; Keil, A; Körner, M; Schmid, RA; Steiner, SK1
Frese, S; Hall, SR; Herrmann, M; Keil, A; Körner, M; Schmid, RA1
Frese, S; Frese-Schaper, M; Gugger, M; Monestier, M; Zbaeren, J1

Other Studies

4 other study(ies) available for irinotecan and Lupus Nephritis

ArticleYear
Low-dose irinotecan improves advanced lupus nephritis in mice potentially by changing DNA relaxation and anti-double-stranded DNA binding.
    Arthritis & rheumatology (Hoboken, N.J.), 2014, Volume: 66, Issue:8

    Topics: Animals; Camptothecin; Disease Progression; DNA; Female; Irinotecan; Lupus Nephritis; Mice; Mice, Inbred NZB; Topoisomerase I Inhibitors

2014
The Topoisomerase I Inhibitor Irinotecan and the Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Furamidine Synergistically Suppress Murine Lupus Nephritis.
    Arthritis & rheumatology (Hoboken, N.J.), 2015, Volume: 67, Issue:7

    Topics: Animals; Benzamidines; Camptothecin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Female; Immunomodulation; Irinotecan; Lupus Nephritis; Mice; Mice, Inbred NZB; Phosphoric Diester Hydrolases; Topoisomerase I Inhibitors; Treatment Outcome

2015
Suppression of lupus nephritis and skin lesions in MRL/lpr mice by administration of the topoisomerase I inhibitor irinotecan.
    Arthritis research & therapy, 2016, 10-22, Volume: 18, Issue:1

    Topics: Animals; Antibodies, Antinuclear; Camptothecin; Disease Models, Animal; DNA; Enzyme-Linked Immunosorbent Assay; Enzyme-Linked Immunospot Assay; Female; Flow Cytometry; Irinotecan; Kidney; Lupus Nephritis; Mice; Mice, Inbred MRL lpr; Random Allocation; Skin; Topoisomerase I Inhibitors

2016
Reversal of established lupus nephritis and prolonged survival of New Zealand black x New Zealand white mice treated with the topoisomerase I inhibitor irinotecan.
    Journal of immunology (Baltimore, Md. : 1950), 2010, Feb-15, Volume: 184, Issue:4

    Topics: Animals; Autoimmune Diseases; Camptothecin; Crosses, Genetic; DNA Topoisomerases, Type I; Enzyme Inhibitors; Female; Irinotecan; Lupus Nephritis; Mice; Mice, Inbred NZB; Proteinuria; Random Allocation; Survival Analysis; Time Factors; Topoisomerase I Inhibitors

2010