irinotecan has been researched along with Liver Steatosis in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 14 (63.64) | 24.3611 |
| 2020's | 4 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Bathe, O; Jacobs, R; Mazurak, VC; Monirujjaman, M; Nelson, R; Pant, A | 1 |
| Ding, C; Gu, Y; Li, Z; Liu, B; Tang, W; Wang, Z; Yu, T; Zhang, C | 1 |
| Dunichand-Hoedl, AR; Isesele, P; Mazurak, VC; Monirujjaman, M; Renani, LB | 1 |
| Bozkurt Duman, B; Çil, T | 1 |
| Gao, S; Ghose, R; Hu, M; Ittmann, MM; Mallick, P; Shah, P; Trivedi, M | 1 |
| Capussotti, L; De Rosa, G; De Saussure, WO; Mentha, G; Rubbia-Brandt, L; Viganò, L | 1 |
| Alexander, HR; Culpepper, WJ; El-Kamary, SS; Jiang, Y; Lane, BF; Mindikoglu, AL; Reddy, SK; Reilly, C; Zhan, M | 1 |
| Aragão, KS; Costa, ML; de Almeida, PR; de Castro Brito, GA; de Mesquita Neto, JW; de Sá Grassi, L; de Souza, MH; Leite, LL; Lima-Júnior, RC; Marques-Neto, RD; Medeiros, RP; Nunes, LG; Ribeiro, RA | 1 |
| Hakamada, K; Hui, FM; Kijima, H; Kudo, D; Miura, T; Morohashi, S; Nanashima, N; Sawano, T; Shimizu, T; Tsuchida, S; Yamada, T | 1 |
| Guo, GL; Schumacher, JD | 1 |
| Hirano, A; Hiroshima, Y; Ishida, Y; Kasahara, K; Kawaguchi, D; Kikuchi, Y; Koda, K; Kosugi, C; Matsuo, K; Mori, M; Murakami, T; Shuto, K; Tanaka, K; Yamada, M; Yamazaki, K | 1 |
| Bosserhoff, A; Dietrich, P; Hellerbrand, C; Koch, A; Lee, S; Luehrmann, A; Mahli, A; Müller, M; Saugspier, M; Schulze-Luehrmann, J; Sommer, J; Thasler, R; Thasler, WE | 1 |
| Khan, AZ; Makuuchi, M; Morris-Stiff, G | 1 |
| Bernheim, J; Buchbut, D; Goldiner, I; Inbar, M; Ish-Shalom, M; Keizman, D; Klein, B; Konikoff, F; Leikin-Frenkel, A; Maimon, N | 1 |
| André, T; Baumgaertner, I; Hannoun, L; Poynard, T; Ratziu, V; Vaillant, JC | 1 |
| Gallinger, S; Guindi, M; Moore, M; Moulton, CA; Nanji, S; Pollett, A; Ryan, P | 1 |
| Bachellier, P; Chenard, MP; Jaeck, D; Pessaux, P | 1 |
| Bruns, H; Büchler, MW; Hoffmann, K; Longerich, T; Mikalauskas, S; Mikalauskiene, L; Nickkholgh, A; Schemmer, P; Strupas, K | 1 |
| Amat, CG; Bermejo, E; Gómez-Ramírez, J; Larrañaga, E; Martín-Pérez, E; Rodríguez, A; Sanz, IG | 1 |
| Fernandez, FG; Goodwin, JW; Hawkins, WG; Linehan, DC; Ritter, J; Strasberg, SM | 1 |
| Cattral, MS; Chan, EK; Dixon, E; Gallinger, S; Grant, DR; Greig, PD; Sahajpal, A; Taylor, BR; Vollmer, CM; Wei, A | 1 |
| Morris-Stiff, G; Tan, YM; Vauthey, JN | 1 |
5 review(s) available for irinotecan and Liver Steatosis
| Article | Year |
|---|---|
Mechanistic review of drug-induced steatohepatitis.
Topics: Amiodarone; Animals; Camptothecin; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Fatty Liver; Hepatocytes; Humans; Irinotecan; Lipid Metabolism; Liver; Methotrexate; Mitochondria, Liver; Organoplatinum Compounds; Oxaliplatin; Perhexiline; Tamoxifen; Tetracycline; Valproic Acid | 2015 |
Patterns of chemotherapy-induced hepatic injury and their implications for patients undergoing liver resection for colorectal liver metastases.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Fatty Liver; Floxuridine; Fluorouracil; Hepatectomy; Hepatic Veno-Occlusive Disease; Humans; Irinotecan; Leucovorin; Liver; Liver Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Risk Factors | 2009 |
[Hepatotoxicity of metastatic colorectal cancer chemotherapy: systematic review].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colorectal Neoplasms; Fatty Liver; Hepatic Veno-Occlusive Disease; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Panitumumab | 2010 |
Consequences of chemotherapy on resection of colorectal liver metastases.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Chemical and Drug Induced Liver Injury; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Delivery Systems; Fatty Liver; Hepatectomy; Hepatic Veno-Occlusive Disease; Humans; Irinotecan; Liver Neoplasms; Liver Regeneration; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Postoperative Complications; Prognosis; Survival Rate; Tomography, X-Ray Computed | 2010 |
Hepatic complications following preoperative chemotherapy with oxaliplatin or irinotecan for hepatic colorectal metastases.
Topics: Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Fatty Liver; Hepatectomy; Hepatic Veno-Occlusive Disease; Humans; Irinotecan; Liver Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin | 2008 |
1 trial(s) available for irinotecan and Liver Steatosis
| Article | Year |
|---|---|
[Influence of pre-surgical chemotherapy on liver parenchyma and post-surgical outcome of patients subjected to hepatectomy due to colorectal carcinoma metastases].
Topics: Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Fatty Liver; Female; Hepatectomy; Hepatic Veno-Occlusive Disease; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Prospective Studies; Treatment Outcome | 2010 |
16 other study(ies) available for irinotecan and Liver Steatosis
| Article | Year |
|---|---|
Alterations in hepatic fatty acids reveal depletion of total polyunsaturated fatty acids following irinotecan plus 5-fluorouracil treatment in an animal model of colorectal cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Disease Models, Animal; Docosahexaenoic Acids; Fatty Acids, Omega-6; Fatty Liver; Female; Fluorouracil; Gene Expression; Irinotecan; Lipid Metabolism; Liver; Rats; Rats, Inbred F344; Signal Transduction; Topoisomerase I Inhibitors; Treatment Outcome; Triglycerides | 2021 |
Hepatic ROS Mediated Macrophage Activation Is Responsible for Irinotecan Induced Liver Injury.
Topics: Acetylcysteine; Animals; Chemical and Drug Induced Liver Injury, Chronic; Fatty Liver; Hepatocytes; Irinotecan; Macrophage Activation; Mice | 2022 |
Increased Expression of Hepatic Stearoyl-CoA Desaturase (SCD)-1 and Depletion of Eicosapentaenoic Acid (EPA) Content following Cytotoxic Cancer Therapy Are Reversed by Dietary Fish Oil.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Fatty Liver; Female; Fish Oils; Fluorouracil; Interleukin-4; Irinotecan; Leptin; Liver; Neoplasms; Rats; Stearoyl-CoA Desaturase; Triglycerides | 2023 |
Steatohepatitis due to FOLFIRINOX regimen in adjuvant pancreas cancer treatment mimicking liver metastasis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Fatty Liver; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Middle Aged; Oxaliplatin; Pancreatic Neoplasms | 2020 |
Impact of diet on irinotecan toxicity in mice.
Topics: Animals; Body Weight; Camptothecin; Carboxylesterase; Diarrhea; Diet; Fatty Liver; Glucuronidase; Irinotecan; Male; Metabolome; Mice, Inbred C57BL; Toxicity Tests | 2018 |
Liver resection for colorectal metastases after chemotherapy: impact of chemotherapy-related liver injuries, pathological tumor response, and micrometastases on long-term survival.
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Combined Modality Therapy; Fatty Liver; Female; Hepatectomy; Hepatic Veno-Occlusive Disease; Humans; Irinotecan; Liver Neoplasms; Male; Neoplasm Invasiveness; Neoplasm Micrometastasis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Survival Rate; Treatment Outcome | 2013 |
Long-term influence of chemotherapy on steatosis-associated advanced hepatic fibrosis.
Topics: Antineoplastic Agents; Camptothecin; Cohort Studies; Fatty Liver; Female; Fluorouracil; Humans; Irinotecan; Liver Cirrhosis; Male; Middle Aged; Multivariate Analysis; Probability; Retrospective Studies; Risk Factors | 2014 |
Chemotherapy-associated steatohepatitis induced by irinotecan: a novel animal model.
Topics: Alanine Transaminase; Animals; Antineoplastic Agents, Phytogenic; Aspartate Aminotransferases; Camptothecin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fatty Liver; Humans; Interleukin-1beta; Irinotecan; Liver; Male; Mice; Peroxidase; Time Factors; Tumor Necrosis Factor-alpha; Weight Loss | 2014 |
Fatty acid synthase-positive hepatocytes and subsequent steatosis in rat livers by irinotecan.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Disease Models, Animal; Fatty Acid Synthases; Fatty Liver; Hepatocytes; Immunohistochemistry; Irinotecan; Liver; Male; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction | 2015 |
Fractal Dimension of Tc-99m DTPA GSA Estimates Pathologic Liver Injury due to Chemotherapy in Liver Cancer Patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Fluorouracil; Fractals; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Predictive Value of Tests; Radionuclide Imaging; Radiopharmaceuticals; Risk Factors; ROC Curve; Technetium Tc 99m Aggregated Albumin; Technetium Tc 99m Pentetate | 2016 |
ERK activation and autophagy impairment are central mediators of irinotecan-induced steatohepatitis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Autophagy; Camptothecin; Disease Models, Animal; Fatty Liver; Hepatocytes; Humans; In Vitro Techniques; Irinotecan; Liver Neoplasms; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Preoperative Care | 2018 |
An animal model for chemotherapy-associated steatohepatitis and its prevention by the oral administration of fatty acid bile acid conjugate.
Topics: Animals; Bile Acids and Salts; Camptothecin; Disease Models, Animal; Fatty Acids; Fatty Liver; Irinotecan; Mice; Mice, Inbred C57BL; Organoplatinum Compounds; Oxaliplatin | 2010 |
Chemotherapy-induced liver injury in metastatic colorectal cancer: semiquantitative histologic analysis of 334 resected liver specimens shows that vascular injury but not steatohepatitis is associated with preoperative chemotherapy.
Topics: Antineoplastic Agents; Camptothecin; Chemical and Drug Induced Liver Injury; Colorectal Neoplasms; Fatty Liver; Female; Humans; Irinotecan; Liver Circulation; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies | 2010 |
Dietary glycine protects from chemotherapy-induced hepatotoxicity.
Topics: Animals; Antineoplastic Agents; Camptothecin; Chemical and Drug Induced Liver Injury; Colorectal Neoplasms; Dietary Supplements; Drug-Related Side Effects and Adverse Reactions; Fatty Liver; Female; Fluorouracil; Glycine; Immunohistochemistry; Irinotecan; Kupffer Cells; Leucovorin; Liver; Microcirculation; Neoadjuvant Therapy; Nitric Oxide Synthase Type II; Organoplatinum Compounds; Oxaliplatin; Phagocytosis; Rats; Rats, Sprague-Dawley; Transaminases | 2011 |
Effect of steatohepatitis associated with irinotecan or oxaliplatin pretreatment on resectability of hepatic colorectal metastases.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Fatty Liver; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Prospective Studies; Risk Factors; Topoisomerase I Inhibitors | 2005 |
Chemotherapy for colorectal cancer prior to liver resection for colorectal cancer hepatic metastases does not adversely affect peri-operative outcomes.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Cohort Studies; Colorectal Neoplasms; Drug Administration Schedule; Fatty Liver; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Preoperative Care; Retrospective Studies; Treatment Outcome | 2007 |