Page last updated: 2024-08-24

irinotecan and Leukemia, Myeloid, Acute

irinotecan has been researched along with Leukemia, Myeloid, Acute in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Chen, C; Jiang, Z; Liu, J; Liu, Q; Wang, A; Wang, L; Wang, W; Yu, K; Zou, F1
Bohnenberger, H; Farin, HF; Gerlach, K; Godavarthy, PS; Hoang, VT; Krause, DS; Llavona, P; Michels, BE; Müller-Kuller, U; Oehler, VG; Oellerich, T; Steiner, M; Verma, D; Voutsinas, JM; Wachter, A; Weissenberger, E; Zörnig, M1
Akiyama, H; Kurosu, T; Miura, O; Murakami, N; Sakashita, C; Umezawa, Y; Yamamoto, M1
Bourhis, JH; Damaj, G; Dreyfus, F; Fenaux, P; Feremans, W; Guerci, A; Ravoet, C; Ribrag, V; Suzan, F; Vantelon, JM1
Baer, MR; Conroy, JM; Li, S; McQuaid, D; Minderman, H; Nowak, NJ; O'Loughlin, KL; Pendyala, L; Quinn, P1
Caron, P; Liu, D; Patel, S; Seiter, K1
Masaoka, T; Ohashi, Y; Ohno, R; Okada, K; Ota, K; Shirakawa, S; Taguchi, T1
Ariyoshi, Y; Furue, H; Kimura, I; Masaoka, T; Ogawa, M; Oguro, M; Ohno, R; Saito, H; Sakai, Y; Yoshida, Y1

Trials

3 trial(s) available for irinotecan and Leukemia, Myeloid, Acute

ArticleYear
Phase II trial of CPT-11 in myelodysplastic syndromes with excess of marrow blasts.
    Leukemia, 2003, Volume: 17, Issue:2

    Topics: Aged; Anemia, Refractory, with Excess of Blasts; Antineoplastic Agents, Phytogenic; Blast Crisis; Bone Marrow; Camptothecin; Disease Progression; Female; Humans; Infusions, Intravenous; Irinotecan; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Survival Analysis; Time Factors

2003
[Late phase II clinical study of irinotecan hydrochloride (CPT-11) in the treatment of malignant lymphoma and acute leukemia. The CPT-11 Research Group for Hematological Malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:7

    Topics: Adolescent; Adult; Aged; Anorexia; Antineoplastic Agents, Phytogenic; Camptothecin; Diarrhea; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Irinotecan; Leukemia, Myeloid, Acute; Leukemia, T-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1994
[An early phase II study of CPT-11 (irinotecan hydrochloride) in patients with hematological malignancies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Diarrhea; Drug Administration Schedule; Female; Hodgkin Disease; Humans; Irinotecan; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Nausea; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1994

Other Studies

5 other study(ies) available for irinotecan and Leukemia, Myeloid, Acute

ArticleYear
All-trans retinoic acid exerts selective anti-FLT3-ITD acute myeloid leukemia efficacy through downregulating Chk1 kinase.
    Cancer letters, 2020, 03-31, Volume: 473

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Checkpoint Kinase 1; Child, Preschool; DNA Damage; DNA Repair; Down-Regulation; Drug Synergism; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Leukemic; Humans; Irinotecan; Leukemia, Myeloid, Acute; Male; Mice; Middle Aged; Mitosis; Primary Cell Culture; Protein Kinase Inhibitors; Tandem Repeat Sequences; Topoisomerase I Inhibitors; Tretinoin; Xenograft Model Antitumor Assays

2020
The transcriptional regulator FUBP1 influences disease outcome in murine and human myeloid leukemia.
    Leukemia, 2019, Volume: 33, Issue:7

    Topics: Animals; Apoptosis; Bone Marrow Transplantation; Cell Cycle; Disease Models, Animal; DNA Damage; DNA-Binding Proteins; Humans; Irinotecan; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Mice; Mice, Inbred C57BL; RNA-Binding Proteins; Topoisomerase I Inhibitors; Tumor Cells, Cultured

2019
Therapy-related leukemia with Inv(16)(p13.1q22) and type D CBFB/MYH11 developing after exposure to irinotecan-containing chemoradiotherapy.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:6

    Topics: Adult; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoradiotherapy; Chromosomes, Human, Pair 16; Female; Humans; Irinotecan; Leukemia, Myeloid, Acute; Oncogene Proteins, Fusion; Treatment Outcome

2015
In vitro and in vivo irinotecan-induced changes in expression profiles of cell cycle and apoptosis-associated genes in acute myeloid leukemia cells.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:6

    Topics: Apoptosis; Camptothecin; Cell Cycle; Cluster Analysis; DNA, Complementary; Down-Regulation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Irinotecan; Kinetics; Leukemia, Myeloid, Acute; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; RNA, Messenger; Transcription, Genetic; Up-Regulation

2005
Acute myelogenous leukemia following irinotecan-based chemotherapy for adenocarcinoma of the small intestine.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:5

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Fluorouracil; Humans; Intestinal Neoplasms; Intestine, Small; Irinotecan; Leucovorin; Leukemia, Myeloid, Acute; Male; Prognosis; Recurrence; Remission Induction

2007