irinotecan has been researched along with Ewing Sarcoma in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (10.81) | 29.6817 |
| 2010's | 19 (51.35) | 24.3611 |
| 2020's | 14 (37.84) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, S; Gu, J; Guo, W; Huang, Y; Ren, T; Sun, K; Sun, X; Tang, X; Xie, L; Xu, J; Yang, F; Yang, R | 1 |
| Lin, GH; Wang, BC; Xiao, BY | 1 |
| Ahmed, MA; Basaran, M; Dogan, I; Iribas, A | 1 |
| Badgett, T; Crimella, J; Fridley, BL; Gill, J; Gorlick, R; Llosa, N; Metts, JL; Reed, D; Sandler, E; Sansil, S; Smith, T; Thapa, R; Thompson, P; Trucco, M; Weiser, DA | 1 |
| Meyers, PA; Slotkin, EK | 1 |
| Aliç, T; Hassa, E | 1 |
| André, N | 1 |
| Cai, Z; Guo, W; Liang, X; Liu, K; Sun, X; Tang, X; Xie, L; Xu, J | 1 |
| Anderson, P; Bognar, E; Crompton, BD; Ghisoli, M; Horvath, S; Klega, KS; Manley, M; Manning, L; Nemunaitis, J; Slotkin, EK; Stanbery, L; Wallraven, G; Wexler, LH | 1 |
| Bautista, F; Brennan, BJ; Campbell-Hewson, Q; Cañete Nieto, A; Casanova, M; Chung, JW; Corradini, N; Geoerger, B; Makin, G; Marshall, LV; Mueller, U; Ploeger, BA; Verschuur, AC; Zebger-Gong, H | 1 |
| Carrabotta, M; Cristalli, C; Donati, DM; Ferracin, M; Giusti, V; Ianzano, ML; Landuzzi, L; Lollini, PL; Magnani, M; Manara, MC; Nanni, P; Nicoletti, G; Palladini, A; Parra, A; Pasello, M; Picci, P; Righi, A; Ruzzi, F; Scotlandi, K | 1 |
| Brohl, AS; Cubitt, CL; Fridley, B; Kahen, E; Reed, DR; Welch, D | 1 |
| Balaguer-Lluna, L; Burgueño, V; Carcaboso, AM; Castañeda, A; Castillo-Ecija, H; Cuadrado-Vilanova, M; de Alava, E; Garcia-Dominguez, DJ; Gomez-Gonzalez, S; Hontecillas-Prieto, L; Lavarino, C; Monterrubio, C; Mora, J; Olaciregui, NG; Paco, S; Pascual-Pasto, G; Perez-Jaume, S; Resa-Pares, C; Restrepo-Perdomo, C; Roldan, M; Santa-Maria, V; Suñol, M; Vila-Ubach, M | 1 |
| Abuhijla, F; Abuhijlih, R; Alnsour, A; Halalsheh, H; Ismail, T; Khozouz, O; Lewin, J; Salah, S; Shahin, O; Sultan, I; To, YH; Yaser, S | 1 |
| Balaguer-Lluna, L; Baulenas-Farres, M; Burgueño, V; Carcaboso, AM; Carrasco, R; Castañeda, A; Castillo-Ecija, H; Celis, V; Cruz, O; Cuadrado-Vilanova, M; Garraus, M; Gorostegui, M; Jimenez-Cabaco, A; Krauel, L; Lavarino, C; Manzanares, A; Monterrubio, C; Mora, J; Morales La Madrid, A; Muñoz-Aznar, O; Olaciregui, NG; Pascual-Pasto, G; Perez-Jaume, S; Resa-Pares, C; Salvador, N; Santa-Maria, V; Suñol, M; Torner, F; Vancells, M; Vicario, FJ; Vila-Ubach, M | 1 |
| Ju, HY; Kang, HG; Kim, JH; Lee, JA; Park, BK; Park, HJ; Park, M; Park, SY; Yang, HC | 1 |
| Naviglio, S; Rabusin, M | 1 |
| Ebadi, M; Gordon, DJ; Gordon, PM; Harki, DA; Jonart, LA; Naumann, JA; Tang, J; Widen, JC | 1 |
| Büyükkapu Bay, S; Çakır, FB; Darendeliler, E; Görgün, O; Kebudi, R; Zülfikar, B | 1 |
| Cripe, T; Geller, J; Nagarajan, R; Turpin, B; Wagner, L; Weiss, B | 1 |
| Bilska, K; Chaber, R; Drabko, K; Pogorzala, M; Polczyńska, K; Raciborska, A; Rodriguez-Galindo, C; Rogowska, E; Wozniak, W; Wyrobek, E | 1 |
| Morland, B; Platt, K; Whelan, JS | 1 |
| D'Incalci, M; Grohar, PJ; Helman, LJ; Mendoza, A; Pommier, Y; Segars, LE; Yeung, C | 1 |
| Burdach, S | 1 |
| Joo, J; Kwon, MM; Lim, KY; Park, BK; Park, HJ; Park, SY; Yoon, JH | 1 |
| Ilhan, IE; Kurucu, N; Sari, N | 1 |
| Bahrami, A; Benavente, C; Bradley, C; Calabrese, C; Caufield, W; Dyer, MA; Freeman, BB; Gordon, B; Goshorn, R; Griffiths, LM; Hatfield, MJ; Karlström, Å; Loh, A; Miller, GM; Pappo, A; Potter, PM; Sablauer, A; Shelat, AA; Shirinifard, A; Snyder, SE; Stewart, E; Thiagarajan, S; Tsurkan, L; Twarog, NR; Wu, J | 1 |
| Calderon, RI; Cruz, RE; Drummond, DC; Fitzgerald, JB; Hall, CP; Hindle, A; Kang, MH; Ko, W; Lee, JS; Makena, MR; Paz, N; Reynolds, CP; Song, MM; Triche, TJ; Wang, J | 1 |
| Burdach, S; D'Incalci, M; DaPrada, GA; Fregoni, V; Grohar, PJ; Pavesi, L; Riccardi, A; Tancredi, R; Zambelli, A | 1 |
| Cassinelli, G; De Cesare, M; Lanzi, C; Zaffaroni, N; Zuco, V | 1 |
| Collier, AB; Gresh, RC; Kamara, DF; Kolb, EA; Sampson, VB; Vetter, NS | 1 |
| Baumgart, JT; Edessa, LD; Helman, LJ; Heske, CM; Lee, S; Mendoza, A; Neckers, L; Proia, DA; Trepel, J | 1 |
| Aviles, PM; Boguslawski, EA; Bowman, MJ; D'Incalci, M; Easton, MK; Galmarini, CM; Grohar, PJ; Guillen Navarro, MJ; Harlow, ML; Hostetter, G; Johnson, BK; Kitchen-Goosen, SM; Madaj, ZB; Maloney, N; Roland, J; Turner, L; Winn, ME | 1 |
| Casey, DA; Chou, AJ; Merchant, MS; Merola, PR; Meyers, PA; Price, AP; Wexler, LH | 1 |
| Adams, R; Albritton, K; Coffin, C; Goldsby, R; Pulsipher, M; Wagner, L | 1 |
| Albritton, K; Goldsby, RE; McAllister, N; McCarville, MB; McNall-Knapp, RY; Rausen, AR; Wagner, LM | 1 |
| Calleja, E; Cosetti, M; Gerald, W; Gorlick, R; Healey, JH; Huvos, AG; LaQuaglia, M; Meyers, PA; Trippett, T; Wexler, LH | 1 |
3 review(s) available for irinotecan and Ewing Sarcoma
| Article | Year |
|---|---|
Irinotecan dose schedule for the treatment of Ewing sarcoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Dacarbazine; Humans; Irinotecan; Neoplasm Recurrence, Local; Neuroectodermal Tumors, Primitive, Peripheral; Sarcoma, Ewing; Temozolomide | 2023 |
Irinotecan and temozolamide treatment for relapsed Ewing sarcoma: a single-center experience and review of the literature.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Child; Child, Preschool; Dacarbazine; Disease-Free Survival; Female; Humans; Infant; Irinotecan; Male; Retrospective Studies; Sarcoma, Ewing; Survival Rate; Temozolomide | 2015 |
Irinotecan for pediatric solid tumors: the Memorial Sloan-Kettering experience.
Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Bone Marrow Diseases; Bone Neoplasms; Camptothecin; Child; Child, Preschool; Diarrhea; Drug Evaluation; Enzyme Inhibitors; Female; Humans; Irinotecan; Lymphoma, Non-Hodgkin; Male; Neoplasm Proteins; Neoplasms; Neuroectodermal Tumors, Primitive; New York City; Osteosarcoma; Retrospective Studies; Rhabdomyosarcoma; Sarcoma, Ewing; Topoisomerase I Inhibitors; Treatment Outcome | 2002 |
8 trial(s) available for irinotecan and Ewing Sarcoma
| Article | Year |
|---|---|
A phase I trial of metformin in combination with vincristine, irinotecan, and temozolomide in children with relapsed or refractory solid and central nervous system tumors: A report from the national pediatric cancer foundation.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Central Nervous System Neoplasms; Child; Child, Preschool; Dacarbazine; Humans; Irinotecan; Maximum Tolerated Dose; Metformin; Neoplasm Recurrence, Local; Neoplasms; Sarcoma, Ewing; Temozolomide; Vincristine | 2023 |
Longer versus Shorter Schedules of Vincristine, Irinotecan, and Temozolomide (VIT) for Relapsed or Refractory Ewing Sarcoma: A Randomized Controlled Phase 2 Trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Dacarbazine; Humans; Irinotecan; Neoplasm Recurrence, Local; Sarcoma, Ewing; Temozolomide; Vincristine | 2023 |
Regorafenib plus Vincristine and Irinotecan in Pediatric Patients with Recurrent/Refractory Solid Tumors: An Innovative Therapy for Children with Cancer Study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Humans; Irinotecan; Rhabdomyosarcoma; Sarcoma, Ewing; Therapies, Investigational; Vincristine | 2023 |
Pilot study of vincristine, oral irinotecan, and temozolomide (VOIT regimen) combined with bevacizumab in pediatric patients with recurrent solid tumors or brain tumors.
Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Cefixime; Child; Child, Preschool; Dacarbazine; Female; Humans; Infant; Irinotecan; Male; Neoplasm Recurrence, Local; Pilot Projects; Sarcoma, Ewing; Temozolomide; Vincristine | 2013 |
Vincristine, irinotecan, and temozolomide in patients with relapsed and refractory Ewing sarcoma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Dacarbazine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Irinotecan; Male; Remission Induction; Retrospective Studies; Sarcoma, Ewing; Survival Rate; Temozolomide; Time Factors; Vincristine | 2013 |
A phase II window study of irinotecan (CPT-11) in high risk Ewing sarcoma: a Euro-E.W.I.N.G. study.
Topics: Adolescent; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Camptothecin; Child; Humans; Irinotecan; Risk; Sarcoma, Ewing | 2014 |
A study of docetaxel and irinotecan in children and young adults with recurrent or refractory Ewing sarcoma family of tumors.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Child; Child, Preschool; Disease-Free Survival; Docetaxel; Drug Administration Schedule; Female; Humans; Irinotecan; Male; Neoplasm Recurrence, Local; Prospective Studies; Sarcoma, Ewing; Taxoids; Young Adult | 2014 |
Irinotecan and temozolomide for Ewing sarcoma: the Memorial Sloan-Kettering experience.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Camptothecin; Child; Child, Preschool; Colitis; Dacarbazine; Diarrhea; Female; Humans; Irinotecan; Male; Neutropenia; Pneumonia; Recurrence; Remission Induction; Retrospective Studies; Sarcoma, Ewing; Temozolomide; Thrombocytopenia; Young Adult | 2009 |
26 other study(ies) available for irinotecan and Ewing Sarcoma
| Article | Year |
|---|---|
Quality of life and Q-TWiST were not adversely affected in Ewing sarcoma patients treated with combined anlotinib, irinotecan, and vincristine: (Peking University People's Hospital Ewing sarcoma trial-02, PKUPH-EWS-02).
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Disease Progression; Female; Humans; Indoles; Irinotecan; Male; Neuroectodermal Tumors, Primitive, Peripheral; Prospective Studies; Quality of Life; Quinolines; Sarcoma, Ewing; Treatment Outcome; Vincristine; Young Adult | 2021 |
Irinotecan plus temozolomide in relapsed Ewing sarcoma: an integrated analysis of retrospective studies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Dacarbazine; Humans; Irinotecan; Neoplasm Recurrence, Local; Neutropenia; Retrospective Studies; Sarcoma, Ewing; Temozolomide | 2022 |
Efficacy of the VIT (vincristine, irinotecan and temozolomide) regimen in adults with metastatic Ewing sarcoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Dacarbazine; Humans; Irinotecan; Retrospective Studies; Sarcoma, Ewing; Temozolomide; Vincristine | 2023 |
Ewing sarcoma: what trends in recent works? A holistic analysis with global productivity: A cross-sectional study.
Topics: Child; Cross-Sectional Studies; Humans; Irinotecan; Neuroectodermal Tumors, Primitive, Peripheral; Sarcoma, Ewing; Temozolomide | 2022 |
Comment on: Irinotecan dose schedule for the treatment of Ewing sarcoma-protracted/metronomic schedule-wording matters!
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Humans; Irinotecan; Neuroectodermal Tumors, Primitive, Peripheral; Sarcoma, Ewing | 2023 |
Pilot Study of Recurrent Ewing's Sarcoma Management with Vigil/Temozolomide/Irinotecan and Assessment of Circulating Tumor (ct) DNA.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Circulating Tumor DNA; Humans; Irinotecan; Middle Aged; Modafinil; Neoplasm Recurrence, Local; Pilot Projects; Sarcoma, Ewing; Temozolomide; Young Adult | 2023 |
Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations.
Topics: 12E7 Antigen; Animals; Antibodies; Antineoplastic Agents; Bone Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Mice; Mice, Inbred NOD; Mice, SCID; Osteosarcoma; Sarcoma, Ewing; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2019 |
Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines.
Topics: Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cyclophosphamide; Depsipeptides; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Etoposide; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone Demethylases; Humans; Hydrazines; Irinotecan; Sarcoma, Ewing; Sulfonamides; Vincristine | 2019 |
Treatment-driven selection of chemoresistant Ewing sarcoma tumors with limited drug distribution.
Topics: Adolescent; Animals; Antineoplastic Agents; Bone Neoplasms; Humans; Irinotecan; Mice; Pharmaceutical Preparations; Sarcoma, Ewing | 2020 |
Irinotecan and temozolomide chemotherapy in paediatric and adult populations with relapsed Ewing Sarcoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Diarrhea; Disease Progression; Drug Administration Schedule; Humans; Irinotecan; Kaplan-Meier Estimate; Neoplasm Recurrence, Local; Progression-Free Survival; Response Evaluation Criteria in Solid Tumors; Retrospective Studies; Salvage Therapy; Sarcoma, Ewing; Temozolomide | 2021 |
Prognostic value of patient-derived xenograft engraftment in pediatric sarcomas.
Topics: Adolescent; Animals; Child; Child, Preschool; Disease Models, Animal; Female; Heterografts; Humans; Irinotecan; Male; Mice; Osteosarcoma; Prognosis; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Treatment Outcome; Xenograft Model Antitumor Assays | 2021 |
Vincristine, Irinotecan, and Temozolomide as a Salvage Regimen for Relapsed or Refractory Sarcoma in Children and Young Adults.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Female; Humans; Irinotecan; Male; Neoplasm Recurrence, Local; Osteosarcoma; Retrospective Studies; Sarcoma, Ewing; Temozolomide; Vincristine; Young Adult | 2022 |
Irinotecan-induced muscular contractions.
Topics: Abdominal Muscles; Administration, Intravenous; Administration, Oral; Adolescent; Bone Neoplasms; Humans; Irinotecan; Male; Muscle Contraction; Sarcoma, Ewing; Temozolomide | 2018 |
SN-38 Conjugated Gold Nanoparticles Activated by Ewing Sarcoma Specific mRNAs Exhibit In Vitro and In Vivo Efficacy.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Gold; Humans; In Vitro Techniques; Irinotecan; Metal Nanoparticles; RNA, Messenger; Sarcoma, Ewing; Topoisomerase I Inhibitors | 2018 |
Vincristine, irinotecan, and temozolomide treatment for refractory/relapsed pediatric solid tumors: A single center experience.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; Female; Humans; Infant; Irinotecan; Kidney Neoplasms; Male; Neoplasm Recurrence, Local; Neuroblastoma; Osteosarcoma; Remission Induction; Retreatment; Rhabdomyosarcoma; Sarcoma, Ewing; Survival Rate; Temozolomide; Vincristine; Wilms Tumor | 2019 |
Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growth.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Dioxoles; Disease Models, Animal; DNA Breaks, Double-Stranded; DNA Damage; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Exodeoxyribonucleases; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Irinotecan; Mice; Oncogene Proteins, Fusion; Phenotype; Proto-Oncogene Protein c-fli-1; RecQ Helicases; RNA Interference; RNA-Binding Protein EWS; RNA, Small Interfering; Sarcoma, Ewing; Tetrahydroisoquinolines; Trabectedin; Werner Syndrome Helicase; Xenograft Model Antitumor Assays | 2014 |
Molecular precision chemotherapy: overcoming resistance to targeted therapies?
Topics: Animals; Antineoplastic Agents; Camptothecin; Dioxoles; DNA Damage; Female; Humans; Irinotecan; Oncogene Proteins, Fusion; Proto-Oncogene Protein c-fli-1; RNA-Binding Protein EWS; Sarcoma, Ewing; Tetrahydroisoquinolines; Trabectedin | 2014 |
Targeting the DNA repair pathway in Ewing sarcoma.
Topics: Animals; Benzimidazoles; Camptothecin; Cell Death; Cell Line, Tumor; Dacarbazine; DNA Breaks, Double-Stranded; DNA Repair; Drug Synergism; Enzyme Inhibitors; Irinotecan; Mice, Nude; Molecular Targeted Therapy; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Sarcoma, Ewing; Temozolomide; Xenograft Model Antitumor Assays | 2014 |
Activity of MM-398, nanoliposomal irinotecan (nal-IRI), in Ewing's family tumor xenografts is associated with high exposure of tumor to drug and high SLFN11 expression.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Disease Models, Animal; Drug Combinations; Female; Gene Expression; Humans; Irinotecan; Liposomes; Macrophages; Mice; Nuclear Proteins; Sarcoma, Ewing; Sucrose; Tissue Distribution; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Targeting the EWS-FLI1 transcription factor in Ewing sarcoma.
Topics: Adult; Camptothecin; Dioxoles; Humans; Irinotecan; Male; Oncogene Proteins, Fusion; Proto-Oncogene Protein c-fli-1; RNA-Binding Protein EWS; Sarcoma, Ewing; Tetrahydroisoquinolines; Trabectedin | 2015 |
PLK1 is a critical determinant of tumor cell sensitivity to CPT11 and its inhibition enhances the drug antitumor efficacy in squamous cell carcinoma models sensitive and resistant to camptothecins.
Topics: Activation, Metabolic; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Child; Drug Resistance, Neoplasm; Female; G2 Phase Cell Cycle Checkpoints; Humans; Irinotecan; Mice; Mice, Nude; Molecular Targeted Therapy; Neoplasm Proteins; Polo-Like Kinase 1; Prodrugs; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proteolysis; Proto-Oncogene Proteins; Pteridines; Rhabdomyosarcoma, Embryonal; Sarcoma, Ewing; Skin Neoplasms; Topoisomerase I Inhibitors; Ubiquitination; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2015 |
Vorinostat Enhances Cytotoxicity of SN-38 and Temozolomide in Ewing Sarcoma Cells and Activates STAT3/AKT/MAPK Pathways.
Topics: Acetylation; Antineoplastic Agents; Apoptosis; Camptothecin; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; DNA Damage; G1 Phase Cell Cycle Checkpoints; Heterocyclic Compounds, 3-Ring; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Irinotecan; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Sarcoma, Ewing; Signal Transduction; STAT3 Transcription Factor; Temozolomide; Tumor Suppressor Protein p53; Vorinostat | 2015 |
STA-8666, a novel HSP90 inhibitor/SN-38 drug conjugate, causes complete tumor regression in preclinical mouse models of pediatric sarcoma.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Child; Disease Models, Animal; DNA Damage; Drug Evaluation, Preclinical; Female; HSP90 Heat-Shock Proteins; Humans; Irinotecan; Mice; Mice, Knockout; Mice, SCID; Resorcinols; Rhabdomyosarcoma; Sarcoma, Ewing; Topoisomerase I Inhibitors; Tumor Burden; Xenograft Model Antitumor Assays | 2016 |
Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus.
Topics: Animals; Camptothecin; Cell Line, Tumor; Female; Humans; Irinotecan; Mice; Mice, Nude; Oncogene Proteins; Oncogene Proteins, Fusion; Proto-Oncogene Protein c-fli-1; RNA-Binding Protein EWS; Sarcoma, Ewing | 2016 |
Unexpected pleural effusions in 3 pediatric patients treated with STI-571.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Marrow Transplantation; Camptothecin; Child; Combined Modality Therapy; Edema; Enzyme Inhibitors; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Irinotecan; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemic Infiltration; Lung Neoplasms; Male; Neoplasm Proteins; Neuroectodermal Tumors, Primitive; Piperazines; Pleural Effusion; Proto-Oncogene Proteins c-kit; Pyrimidines; Remission Induction; Sarcoma, Ewing; Testis; Topotecan | 2002 |
Temozolomide and intravenous irinotecan for treatment of advanced Ewing sarcoma.
Topics: Administration, Oral; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Child; Dacarbazine; Female; Humans; Injections, Intravenous; Irinotecan; Male; Neoplasm Metastasis; Sarcoma, Ewing; Temozolomide | 2007 |