Page last updated: 2024-08-24

irinotecan and Esophageal Squamous Cell Carcinoma

irinotecan has been researched along with Esophageal Squamous Cell Carcinoma in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (33.33)24.3611
2020's8 (66.67)2.80

Authors

AuthorsStudies
Adenis, A; Al-Rajabi, R; Amonkar, M; Bhagia, P; de la Fouchardiere, C; Girotto, GC; Kulkarni, AS; Mansoor, W; Metges, JP; Norquist, J; Senellart, H; Suryawanshi, S; van Laarhoven, HWM1
Bai, C; Bai, Y; Chen, X; Cui, C; Cui, T; Dai, G; Fan, Q; Gao, Q; Gu, K; Huang, Y; Ji, S; Li, W; Li, Y; Liao, W; Liu, Y; Ma, D; Ma, Z; Mancao, C; Peng, B; Shu, Y; Sun, J; Tao, M; Wang, J; Wang, X; Wang, Y; Wu, L; Xiao, J; Xu, J; Xu, N; Yang, L; Yang, Y; Zhang, J; Zhang, T; Zhang, Y; Zhou, H1
Chang, J; Hu, Z; Sun, S; Wang, H; Wang, J; Wu, X; Yu, H; Zhao, X1
Cai, G; Cai, X; Chen, Y; Gong, Y; Ke, S; Qiu, H; Ruan, S; Shi, W; Wu, Y; Zhao, W; Zuo, Z1
Bian, W; Chen, S; Dai, X; Tao, L; Wang, J; Wu, W1
Adenis, A; Barbier, E; Borg, C; Breysacher, G; Dahan, L; Desrame, J; Di Fiore, F; Faroux, R; Gaba, L; Laurent-Puig, P; Lièvre, A; Lopez, A; Louafi, S; Louvet, C; Manfredi, S; Metges, JP; Mineur, L; Randrian, V; Roquin, G; Tougeron, D1
Chen, Y; Gubat, JA; Jia, Q; Li, Y; Liu, M; Min, L; Sun, C; Wang, X; Yang, J; Zhang, X; Zhu, C1
Adenis, A; Al-Rajabi, R; Bennouna, J; Bhagia, P; Chen, J; de la Fouchardiere, C; Doi, T; Enzinger, P; Ferreira, P; Francois, E; Girotto, G; Hsu, CH; Kang, SP; Kato, K; Kim, SB; Kojima, T; Lee, SH; Lordick, F; Metges, JP; Moriwaki, T; Muro, K; Qin, SK; Senellart, H; Shah, MA; Shen, L; Suryawanshi, S; Wang, R1
Chen, Z; Gao, J; Li, S; Li, Y; Lin, X; Lu, Z; Shen, L; Zhang, C; Zou, J1
Chen, L; Fu, MY; Tian, D; Wang, Y; Wen, HY; Zhang, KP; Zhang, L; Zhou, Y1
Ba, Y; Bai, Y; Cheng, Y; Fan, Q; Feng, J; Hu, C; Huang, J; Li, J; Liu, Y; Lu, P; Ma, C; Wang, X; Wen, L; Wu, L; Xu, B; Yuan, X; Zhang, S1
Masuda, U; Matsumoto, A; Minegaki, T; Miyamoto, K; Moriyama, Y; Nishiguchi, K; Ota, K; Tanahashi, M; Tanaka, M; Tsujimoto, M; Wada, A; Yamamoto, A1

Trials

9 trial(s) available for irinotecan and Esophageal Squamous Cell Carcinoma

ArticleYear
Impact of Pembrolizumab Versus Chemotherapy as Second-Line Therapy for Advanced Esophageal Cancer on Health-Related Quality of Life in KEYNOTE-181.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022, 02-01, Volume: 40, Issue:4

    Topics: Adenocarcinoma; Antibodies, Monoclonal, Humanized; Disease Progression; Docetaxel; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Functional Status; Humans; Immune Checkpoint Inhibitors; Irinotecan; Paclitaxel; Quality of Life; Surveys and Questionnaires; Time Factors; Treatment Outcome

2022
Clinical and biomarker analyses of sintilimab versus chemotherapy as second-line therapy for advanced or metastatic esophageal squamous cell carcinoma: a randomized, open-label phase 2 study (ORIENT-2).
    Nature communications, 2022, 02-14, Volume: 13, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Humans; Immune Checkpoint Inhibitors; Irinotecan; Male; Middle Aged; Paclitaxel; Programmed Cell Death 1 Receptor; Progression-Free Survival; Receptors, Antigen, T-Cell

2022
Rh-Endostatin Plus Irinotecan/Cisplatin as Second-Line Therapy for Advanced Esophageal Squamous Cell Carcinoma: An Open-Label, Phase II Study.
    The oncologist, 2022, 04-05, Volume: 27, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Endostatins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Irinotecan

2022
Radiotherapy plus camrelizumab and irinotecan for oligometastatic esophageal squamous cell carcinoma patients after first-line immunotherapy plus chemotherapy failure: An open-label, single-arm, phase II trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2023, Volume: 184

    Topics: Antineoplastic Combined Chemotherapy Protocols; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Immunotherapy; Irinotecan

2023
Efficacy and safety of irinotecan combined with raltitrexed or irinotecan monotherapy for salvage chemotherapy of esophageal squamous cell cancer: A prospective, open label, randomized phase II study.
    Cancer medicine, 2023, Volume: 12, Issue:15

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Irinotecan; Prospective Studies

2023
Nal-IRI/LV5-FU versus paclitaxel as second-line therapy in patients with metastatic esophageal squamous cell carcinoma (OESIRI)-PRODIGE 62: A multicentre, randomised, non-comparative phase II study.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2020, Volume: 52, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase II as Topic; Disease Progression; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Fluorouracil; France; Humans; Irinotecan; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Paclitaxel; Quality of Life; Randomized Controlled Trials as Topic; Survival Rate

2020
Randomized Phase III KEYNOTE-181 Study of Pembrolizumab Versus Chemotherapy in Advanced Esophageal Cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 12-10, Volume: 38, Issue:35

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Docetaxel; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Humans; Irinotecan; Male; Middle Aged; Paclitaxel; Progression-Free Survival; Survival Rate; Young Adult

2020
Neoadjuvant chemotherapy with irinotecan and nedaplatin in a single cycle followed by esophagectomy on cT4 resectable esophageal squamous cell carcinoma: a prospective nonrandomized trial for short-term outcomes.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2019, Mar-01, Volume: 32, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Female; Humans; Irinotecan; Male; Neoadjuvant Therapy; Organoplatinum Compounds; Prospective Studies; Survival Rate; Treatment Outcome

2019
Irinotecan plus S-1 versus S-1 in patients with previously treated recurrent or metastatic esophageal cancer (ESWN 01): a prospective randomized, multicenter, open-labeled phase 3 trial.
    Cancer communications (London, England), 2019, 04-02, Volume: 39, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Drug Combinations; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Humans; Infusions, Intravenous; Irinotecan; Male; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Tegafur; Topoisomerase I Inhibitors

2019

Other Studies

3 other study(ies) available for irinotecan and Esophageal Squamous Cell Carcinoma

ArticleYear
Clinical efficacy of irinotecan plus raltitrexed chemotherapy in refractory esophageal squamous cell cancer.
    Anti-cancer drugs, 2020, Volume: 31, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Resistance, Neoplasm; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Follow-Up Studies; Humans; Irinotecan; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Quinazolines; Retrospective Studies; Salvage Therapy; Survival Rate; Thiophenes

2020
A novel oral camptothecin analog, gimatecan, exhibits superior antitumor efficacy than irinotecan toward esophageal squamous cell carcinoma in vitro and in vivo.
    Cell death & disease, 2018, 05-31, Volume: 9, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; DNA Damage; DNA Topoisomerases, Type I; Esophageal Squamous Cell Carcinoma; Humans; Irinotecan

2018
Synergistic Effects of Olaparib and DNA-damaging Agents in Oesophageal Squamous Cell Carcinoma Cell Lines.
    Anticancer research, 2019, Volume: 39, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cisplatin; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Esophageal Squamous Cell Carcinoma; Histones; Humans; Irinotecan; Phosphorylation; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Temozolomide

2019