Page last updated: 2024-08-24

irinotecan and Cancer of Liver

irinotecan has been researched along with Cancer of Liver in 687 studies

Research

Studies (687)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's25 (3.64)18.2507
2000's294 (42.79)29.6817
2010's311 (45.27)24.3611
2020's57 (8.30)2.80

Authors

AuthorsStudies
Jiang, J; Jing, D; Liang, X; Liu, X; Rashid, HU; Wang, H; Wang, L; Wu, L; Xie, P; Xu, Y1
Aloia, TA; Cao, HST; Chun, YS; Hwang, H; Kawaguchi, Y; Kopetz, S; Panettieri, E; Tzeng, CD; Vauthey, JN; Wang, X1
Bandula, S; Brown, E; Garin, E; Graham, J; Harris, WP; Herrmann, K; Johnson, MS; Kim, TY; Lewandowski, RJ; Mahvash, A; Martin, RCG; Mills, J; Montazeri, AH; Mulcahy, MF; Padia, SA; Pracht, M; Ross, P; Salem, R; Sinclair, P; Sofocleous, CT; Weaver, A; Wilson, G; Yubero Esteban, A; Zuckerman, D1
Chen, X; Chen, Y; Dong, S; Feng, M; He, H; Ho, M; Hu, S; Huang, L; Li, J; Li, W; Liang, R; Liang, X; Xiang, L; Zhu, Y; Zuo, D1
Bruns, C; Damanakis, AI; Deuß, B; Gebauer, F; Göser, T; Held, S; Kütting, F; Lutz, K; Popp, F; Quaas, A; Waldschmidt, D1
Chung, YM; Hu, MC; Khan, PP; Larrick, JW; Qiao, Y; Tsai, WB; Wang, H; Yu, B1
Bagnardi, V; Bonomo, G; Camisassi, N; Della Vigna, P; Frassoni, S; Maiettini, D; Mauri, G; Orsi, F; Rossi, D; Varano, GM; Zampino, MG1
Coburn, N; David, E; Kiss, A; Ni, T; Pugash, R; Raphael, MJ; Voizard, N1
Chen, K; Cheng, Y; Feng, GY; Shi, ZR1
Bian, XL; Chen, B; Jia, W; Li, J; Xi, WQ; Zhang, WX1
Liu, D; Ma, Z; Wang, J; Wen, Z; Xie, H; Yang, X; Zhang, N; Zhao, Y1
Crocenzi, TS; Driscoll, M; Hansen, P; Kelly, LR; Martin, RCG; McMasters, KM; Philips, P; Rocha, F; Scoggins, CR; Sharma, VR; Simo, KA; Tatum, CM1
Chen, Y; Huang, P; Huang, X; Shi, G; Sun, Q; Yang, G; Zhou, Y1
Hu, H; Huang, D; Li, F; Li, J; Mei, Y; Wen, Y; Zhang, W1
Dey, C; Maraj, T; Mirrahimi, A1
Chang, PY; Chang, WC; Chen, PK; Chiu, SH; Hsu, TF; Ko, KH; Lin, HH1
Guo, L; Guo, Y; Hu, M; Lei, K; Liu, J; Liu, Y; Ye, Q; Zhou, T1
Ju, Y; Liu, R; Lu, Y; Niu, T; Qi, W; Wang, D; Yang, J; Zheng, L1
Brock, L; Chung, N; Dunn, SP; Finegold, MJ; Furman, WL; Katzenstein, HM; Krailo, MD; Langham, MR; Malogolowkin, MH; McCarville, EB; McGahren, ED; Meyers, RL; O'Neill, AF; Piao, J; Ranganathan, S; Rodriguez-Galindo, C; Thompson, PA; Tiao, GM; Towbin, AJ; Weldon, CB1
Bohnenberger, H; Ghadimi, M; Kauffels, A; Nowack, H; Sperling, J; Spitzner, M; Sprenger, T1
Alevisopoulos, N; Charokopakis, A; Delicha, E; Emmanouil, E; Filippiadis, DK; Glantzounis, G; Kartsouni, V; Kelekis, N; Kiakidis, T; Malagari, K; Moschouris, H; Panagiotou, I; Pellerin, O; Psarros, G; Tsavaris, N; Vergadis, C1
Chen, M; Han, J; He, G; Huang, R; Li, W; Liu, J; Song, Q; Xu, Y; Yu, Z; Zhang, C; Zhao, L1
Honma, T; Imai, M; Ishikawa, T; Iwanaga, A; Jimbo, R; Kobayashi, Y; Sano, T; Sato, R; Sato, T; Yokoyama, J1
Collettini, F; Gebauer, B; Geisel, D; Jonczyk, M; Meddeb, A; Schnapauff, D; Wieners, G1
Atzpodien, J; Buechner-Steudel, P; Ettrich, T; Florschütz, A; Geissler, M; Greeve, J; Heinemann, V; Held, S; Kanzler, S; Martens, UM; Modest, DP; Nörenberg, D; Reinacher-Schick, AC; Ricke, J; Riera-Knorrenschild, J; Seidensticker, M; Seufferlein, T; Tannapfel, A; Wessendorf, S1
Araida, T; Jibiki, N; Katagiri, S; Kuramochi, H; Nishino, T; Shimmura, H1
Aljubran, A; Alzahrani, A; Badran, A; Bazarbashi, S; Elhassan, T; Omar, AT; Raddaoui, L1
Cao, Y; Li, Q; Liu, Y; Zhang, Y; Zhou, J1
Asch, D; Beatty, GL; Domchek, SM; Nathanson, KL; O'Dwyer, PJ; Reiss, KA; Rosen, MA; Siegelman, ES; Wattenberg, MM; Yu, S1
Caffrey, TC; Clement, EJ; Cook, LM; Costanzo-Garvey, D; DiMaio, DJ; Fisher, KW; Grandgenett, PM; Grem, JL; Hollingsworth, MA; Krieger, KL; Lagundžin, D; Law, HC; Qiao, F; Wagner, ZS; Woods, NT; Yu, F1
Belanger, B; Blanc, JF; Bodoky, G; Chen, LT; Cunningham, D; Dean, A; Lee, KH; Li, CP; Macarulla Mercadé, T; Siveke, JT; Wang-Gillam, A1
Dercle, L; Eggleton, P; Lu, L; Piessevaux, H; Qian, M; Schwartz, LH; Tejpar, S; Zhao, B1
Bozkurt Duman, B; Çil, T1
Abed, A; Boeken, T; Dean, C; Moussa, N; Pellerin, O; Pernot, S; Sapoval, M; Taieb, J1
Kubo, S; Tomita, N; Yamano, T1
Chen, M; Chen, X; Gan, Y; Li, F; Li, Y; Miao, Y; Zhang, X1
Aranda, E; Balbín, M; Bando, I; Bellosillo, B; Calle, SG; Díaz-Rubio, E; García-Alfonso, P; Llovet, P; Lopez, C; Martínez, A; Mediero, B; Moral, VM; Orden, V; Ortiz-Morales, MJ; Palanca, S; Peligros Gomez, MI; Quintero, G; Salud, A; Sastre, J; Viéitez, JM1
Boeken, T; Pellerin, O; Sapoval, M1
Chin, K; Kitagawa, Y; Nakayama, I; Ogura, M; Ooki, A; Osumi, H; Ota, Y; Shinozaki, E; Suenaga, M; Suzuki, T; Takahari, D; Wakatsuki, T; Yamaguchi, K1
Abad, DG; Bockorny, B; Bohana-Kashtan, O; Borad, MJ; Borazanci, E; Chaney, M; Feliu, J; Geva, R; Golan, T; Hidalgo, M; Kadosh, S; Lustig, TM; Macarulla, T; Muñoz, A; Park, JO; Pedersen, KS; Peled, A; Ponz-Sarvise, M; Ramirez, RA; Semenisty, V; Shaw, SM; Sorani, E; Stemmer, SM; Vainstein Haras, A; Von Hoff, DD; Wolpin, BM1
Artru, P; Dahan, L; De La Fouchardière, C; Guimbaud, R; Jouve, JL; Lepage, C; Montérymard, C; Pellerin, O; Pernot, S; Raoul, JL; Sefrioui, D; Smith, D; Taieb, J; Tougeron, D1
Aprile, G; Belfiore, A; Boccaccino, A; Brich, S; Cattaneo, L; Centonze, G; Cillo, U; Corallo, S; Cremolini, C; De Braud, F; Falcone, A; Fassan, M; Fontanini, G; Germani, MM; Lonardi, S; Loupakis, F; Marmorino, F; Milione, M; Morano, F; Morelli, L; Moretto, R; Pietrantonio, F; Prisciandaro, M; Rossini, D; Urbani, L1
Arnold, D; Bauer, R; de Baère, T; Gomez, F; Helmberger, T; Iezzi, R; Kaufmann, N; Maleux, G; Nordlund, A; Pellerin, O; Pereira, PL; Prenen, H; Sangro, B; Taieb, J; Zeka, B1
Khan, GN; Patil, NR1
Chen, J; Dai, S; Huang, X; Li, Y; Lv, Y; Yang, C1
Bakhutashvili, I; Banovac, F; Esparza-Trujillo, JA; Henman, A; Karanian, JW; Krishnasamy, VP; Levy, EB; Lewis, AL; Mikhail, AS; Negussie, AH; Pritchard, WF; Tang, Y; Wakim, PG; Willis, SL; Wood, BJ; Woods, DL1
Chen, F; Gou, S; Hua, S; Liu, Q; Wang, X1
Cha, HS; Hwang, JH; Kim, J; Kim, JW; Kim, MJ; Lee, JC; Lee, WJ; Park, P; Shin, DW; Woo, SM; Yang, SY1
Hironaka, S; Hosokawa, A; Kusaba, H; Matsuda, C; Morita, S; Muro, K; Okamura, S; Shinozaki, K; Shirakawa, T; Tamura, T; Tsuda, M; Tsuda, T; Tsushima, T; Ueda, S; Yamashita, H; Yamazaki, K1
Helmberger, T; Isailovic, TV; Maleux, G; Pereira, P; Prenen, H; Spriet, I1
Arnold, D; Bánsághi, Z; Brountzos, E; Carchesio, F; de Baère, T; Echevarria-Uraga, JJ; Gomez, F; Gonçalves, B; Helmberger, T; Iezzi, R; Inchingolo, R; Kaufmann, N; Maleux, G; Manfredi, R; Nardella, M; Pellerin, O; Pereira, PL; Prenen, H; Sangro, B; Sousa, M; Spiliopoulos, S; Taieb, J; Zeka, B1
Balachandran, VP; Boerner, T; Buisman, FE; D'Angelica, MI; Drebin, JA; Gonen, M; Jarnagin, WR; Kemeny, NE; Kingham, TP; Narayan, RR; Seier, K; Srouji, RM; Wei, A1
Chen, Z; Ke, Q; Tao, Y; Wang, H; Wang, J; Xie, H; Xu, S; Xu, X; Yang, F; Zheng, S; Zhuo, J1
de Bruijn, P; de Bruin, RWF; de Man, FM; Dollé, MET; IJzermans, JNM; Koolen, SLW; Lolkema, MP; Mathijssen, RHJ; Moelker, A; Olieman, JF; Oomen-de Hoop, E; Sandberg, Y; van Doorn, GM; van Eerden, RAG; van Gelder, T; van Halteren, HK; Veraart, JN1
Boeken, T; Douard, R; Gallois, C; Martelli, N; Méatchi, T; Pellerin, O; Sapoval, M; Taieb, J1
Baloni, P; Bergey, D; Hood, LE; Jabbari, N; Kenerson, HL; Lausted, C; Meng, C; Pillarisetty, VG; Sullivan, KM; Tian, Q; Yan, X; Yeung, RS1
Cepero, A; Martin-Guerrero, SM; Martin-Oliva, D; Melguizo, C; Munoz-Gamez, JA; Ortiz, R; Prados, J; Quinonero, F; Urbano, D1
Falkowski, A; Golubinska-Szemitko, E; Sienko, J; Szemitko, M1
Bian, J; Liu, S; Wang, R; Wu, J; Zhang, Y; Zhao, G; Zhao, T; Zhou, J1
Algül, H; Decker, T; Erickson, NT; Gesenhues, AB; Heinemann, V; Heintges, T; Höffkes, HG; Holch, JW; Kahl, C; Kaiser, F; Kiani, A; Kullmann, F; Lerch, MM; Link, H; Liu, L; Michl, M; Modest, DP; Moehler, M; Ricard, I; Scheithauer, W; Stintzing, S; Theurich, S; von Weikersthal, LF1
Beinse, G; Bonnetain, F; Borg, C; Bouché, O; Cleau, D; d'Engremont, C; de Mestier, L; Dupont-Gossart, AC; Fein, F; Heyd, B; Lakkis, Z; Louvet, C; Meurisse, A; Neuzillet, C; Rousseau, B; Tournigand, C; Vernerey, D; Vienot, A1
Adam, R; Barroso, E; Capussotti, L; Elias, D; Giuliante, F; Gruenberger, T; Guglielmi, A; Hubert, C; Innominato, PF; Isoniemi, H; Lapointe, R; Laurent, C; Lin, JK; Lopez-Ben, S; Regimbeau, JM; Skipenko, OG; Yi, B1
Andreou, A; Bahra, M; Beierle, AS; Duwe, G; Knitter, S; Lohneis, P; Öllinger, R; Pesthy, S; Pratschke, J; Raschzok, N; Sauer, IM; Schmelzle, M; Schmuck, RB; Sinn, M; Struecker, B1
Emami, J; Hasanzadeh, F; Maghzi, P; Mirian, M; Rostami, M; Sadeghi, H1
Bai, XL; Chen, YG; Gao, SL; Guo, CX; Li, GG; Li, X; Liang, TB; Lou, JY; Ma, T; Que, RS; Shen, YN; Sun, PW; Wei, QC; Wei, SM; Yu, RS; Yuan, Y; Zhang, Q; Zhang, Y; Zheng, L1
Andreatos, N; Buettner, S; Damaskos, C; Deshwar, A; Ghasebeh, MA; Kamel, IR; Margonis, GA; Pawlik, TM; Pour, MZ; Rezaee, N; Sasaki, K; Wang, J; Weiss, MJ; Wolfgang, CL1
Cohen, D; Ghaffaripour, T; Stoner, P1
Akinwande, O; Dendy, M; Kim, HS; Ludwig, JM1
Adam, R; Boige, V; Bouchahda, M; Carvalho, C; Desterke, C; Ducreux, M; Focan, C; Guimbaud, R; Hebbar, M; Innominato, P; Karaboué, A; Lemoine, A; Lévi, F; Milano, G; Saffroy, R; Smith, D; Taieb, J1
Allen, JN; Berger, D; Blaszkowsky, LS; Clark, JW; Collura, C; Deshpande, V; Ferrone, CR; Lillemoe, KD; Miller, CL; Murphy, JE; Parikh, AR; Qadan, M; Ryan, DP; Smalley, R; Tanabe, KK; Taylor, MS; Worthington, S1
Dunn, SP; Finegold, MJ; Furman, WL; Gao, Y; Katzenstein, HM; Krailo, MD; Langham, MR; Malogolowkin, M; McCarville, MB; McGahren, ED; Meyers, RL; O'Neill, AF; Ranganathan, S; Rodriguez-Galindo, C; Tiao, GM; Towbin, AJ; Weldon, CB; Xia, C1
Bracke, B; Chapelle, T; Driessen, A; Francque, S; Hartman, V; Huyghe, I; Morrison, S; Op de Beeck, B; Roeyen, G; Ysebaert, D1
Azrumelashvili, T; Chikovani, T; Janikashvili, N; Kikodze, N; Mizandari, M; Paksashvili, N; Pantsulaia, I; Shanava, K1
Das, K; Imamura, H; Nishikawa, K; Sugimoto, N; Taguri, M; Tan, P; Tsuburaya, A; Yoshida, K1
Cobos Briz, M; Martakoush María, A; Miranda García, M1
Allen, PJ; Balachandran, VP; Boucher, T; Capanu, M; Cercek, A; Chou, JF; D'Angelica, MI; DeMatteo, RP; Jarnagin, WR; Kemeny, NE; Kingham, TP; Pak, LM1
Chen, HM; Cheng, AL; Lai, MS; Liang, YH; Shao, YY; Yeh, KH1
Alesse, E; Bruera, G; Calvisi, G; Cannita, K; Cocciolone, V; Cortellini, A; Dal Mas, A; Ficorella, C; Mastroiaco, V; Ricevuto, E; Tessitore, A; Zazzeroni, F1
Hashimoto, T; Ichida, A; Makuuchi, M; Maruyama, Y; Shimada, K; Takamoto, T1
Carnaghi, C; Cimino, M; Darwish, SS; Del Fabbro, D; Donadon, M; Personeni, N; Procopio, F; Rimassa, L; Santoro, A; Torzilli, G; Vigano, L1
Pacheco, MM; Powers, JM; Wickiser, JE1
Albrecht, MH; Gruber-Rouh, T; Hammerstingl, R; Lahrsow, M; Thompson, ZM; Vogl, TJ1
Chen, EY; Corless, CL; Deloughery, TG; Kearney, MR; Lopez, CD; Stenzel, P; Zivney, M1
Bacha, D; Bayar, R; Ben Slama, S; Bouraoui, S; Khadhar, A; Lahmar, A; Sassi, A1
Bonomo, G; Della Vigna, P; Mauri, G; Monfardini, L; Orsi, F; Ravenda, PS; Varano, GM; Zampino, MG1
Aravantinos, G; Bafaloukos, D; Efstratiou, I; Fountzilas, G; Goudopoulou, A; Kalogera-Fountzila, A; Kalogeropoulou, L; Karavasilis, V; Kentepozidis, N; Koliou, GA; Kotoula, V; Koumakis, G; Laschos, K; Pectasides, D; Pentheroudakis, G; Petraki, C; Poulios, C; Samantas, E; Sgouros, J; Souglakos, I; Tikas, I; Voutsina, A; Vrettou, E; Zarkavelis, G1
Beeres, M; Eichler, K; Gruber-Rouh, T; Kamal, A; Langenbach, M; Naguib, NN; Vogl, TJ1
Aliberti, C; Carandina, R; Felicioli, A; Fiorentini, G; Guadagni, S; Mulazzani, L; Sarti, D1
Bengrine, L; Collot, T; Fumet, JD; Ghiringhelli, F; Klopfenstein, Q; Vincent, J1
Battaglin, F; Berger, MD; Cao, S; Cremolini, C; Falcone, A; Heinemann, V; Lenz, HJ; Lo, JH; Loupakis, F; Millstein, J; Naseem, M; Puccini, A; Soni, S; Stintzing, S; Tokunaga, R; Zhang, W1
Aleba, A; Bachet, JB; Barbier, E; Breysacher, G; Brocard, F; Desauw, C; Di Fiore, F; Dupuis, OJM; Etienne, PL; Lagasse, JP; Lecomte, T; Lepage, C; Levache, CB; Lucidarme, O; Pernot, S; Raoul, JL; Taieb, J1
Demuth, C; Hoegdall, E; Johansen, JS; Nielsen, D; Pallisgaard, N; Pfeiffer, P; Sorensen, BS; Spindler, KG; Vittrup Jensen, B1
Figg, W; Garcia, C; Greten, T; Hughes, MS; Levy, EB; Lewis, A; Pandalai, P; Peer, C; Peretti, J; Sissung, TM; Venkatesan, A; Wood, B1
Antonuzzo, L; Aprile, G; Avallone, A; Bordonaro, R; Cinieri, S; Di Donato, S; Fanotto, V; Fornaro, L; Gerratana, L; Giampieri, R; Leone, F; Melisi, D; Nichetti, F; Pellegrino, A; Rimassa, L; Rosati, G; Santini, D; Scartozzi, M; Silvestris, N; Stragliotto, S; Tomasello, G; Vasile, E1
Bendell, J; Hochster, HS; Hurwitz, HI; Lee, JJ; Lenz, HJ; Nicholas, A; Palma, JF; Price, R; Reeves, JA; Scappaticci, F; Somer, B; Sommer, N; Tan, BR; Xiong, H1
Nazha, B; Owonikoko, TK1
Bi, F; Chen, Y; Gou, H; Li, Q; Liu, J; Qiu, M; Wu, B; Zhang, J; Zhou, Y1
Kawamoto, K; Koda, Y; Okita, C; Ome, Y1
Belanger, B; Chen, LT; de Jong, FA; Hubner, RA; Mirakhur, B; Siveke, JT; Von Hoff, DD; Wang-Gillam, A1
Bohnenberger, H; Czejka, M; Ghadimi, M; Gruber, A; Kauffels, A; Kitzmüller, M; Kuthning, A; Nowack, H; Sperling, J; Spitzner, M; Sprenger, T1
Ajioka, Y; Aoki, M; Fukunari, H; Hayashi, T; Saito, S; Shitara, K; Tani, Y; Watanabe, A1
Aldrighetti, L; Alexandrescu, S; Bagante, F; Beal, EW; Guglielmi, A; Makris, EA; Margonis, GA; Merath, K; Pawlik, TM; Popescu, I; Poultsides, GA; Ratti, F; Ruzzenente, A; Weiss, MJ1
Agaimy, A; Cavallaro, A; Fietkau, R; Golcher, H; Grützmann, R; Lubgan, D; Pavel, M; Schmidt, D; Semrau, S1
Hall, B; Lewis, AL1
Akaboshi, S; Baba, H; Hayashi, H; Ikuta, Y; Kamio, T; Masuda, T; Matumoto, K; Ogata, K; Ogawa, K; Ozaki, K; Takamori, H1
Bandula, S; Corbo, B; Evans, J; Hague, J; Kibrya, N; Ngo, A; Raja, J; Shiu, KK; von Stempel, C1
Bascal, Z; Caine, M; Czuczman, P; Garcia, P; Hagan, A; Kilpatrick, H; Lewis, AL; Lloyd, AW; Macfarlane, WM; Phillips, G; Press, C; Tang, Y1
Anderson, K; Bullock, A; Saade Lemus, P; Smith, M1
Akinwande, O; Malone, C; Mokkarala, M; Noda, C; Ramaswamy, R1
Rahman, M; Washington, L1
Georgoulias, V; Hatzidaki, D; Katsaounis, P; Kentepozidis, N; Kotsakis, A; Kouroupakis, P; Matikas, A; Messaritakis, I; Nikolaidi, A; Pantazopoulos, N; Prinarakis, E; Souglakos, J; Tzovara, I1
Auerbach, C; Cheron, R; Natarajan, E; Pashankar, F1
Alonso, B; Aranda, E; Arrivi, A; Bando, I; Carrato, A; Conde, V; Díaz-Rubio, E; Elez, E; Gallego, J; Grávalos, C; López, C; Ortiz, MJ; Pericay, C; Ruiz de Mena, I; Safont, MJ; Tabernero, J; Valladares-Ayerbes, M1
Kanno, M; Kichikawa, K; Koyama, F; Marugami, N; Masada, T; Nishiofuku, H; Otsuji, T; Sato, T; Sho, M; Tanaka, T; Tatsumoto, S1
Boukouris, AE; Buitrago-Molina, LE; Hegermann, J; Kirstein, MM; Kühnel, F; Manns, MP; Marhenke, S; Orlik, J; Pothiraju, D; Schütt, J; Vogel, A1
Choo, SP; Chuah, BYS; Cohn, AL; Cottrell, S; Dubey, S; Galimi, F; Hei, YJ; Kopp, MV; Loberg, R; Maurel, J; McCaffery, I; Mitchell, EP; Nowara, E; Pan, Y; Sakaeva, DD; Sastre, J; Suzuki, S; Tabernero, J1
Arora, G; Barbery, K; Guerrero, G; Narayanan, G; Suthar, R1
Huppert, P; Wenzel, T; Wietholtz, H1
Aksu, G; Bilici, A; Cabuk, D; Gumus, M; Kaya, S; Oven Ustaalioglu, BB; Seker, M; Temiz, S; Uygun, K; Yildiz, R1
Carr, DF; Fenwick, SW; Ghaneh, P; Greensmith, RM; Hamlett, J; Jenkins, R; Jones, RP; Kitteringham, NR; Malik, HZ; O'Grady, E; Park, BK; Poston, GJ; Rowe, C; Santoyo-Castelazo, A; Sutton, P; Terlizzo, M1
Biasco, G; Brandi, G; de Rosa, F; Derenzini, E; Di Girolamo, S; Ercolani, G; Falcone, A; Grazi, GL; Loupakis, F; Masi, G; Pantaleo, MA; Pietrabissa, A; Pinna, AD1
Biondi, M; Fusco, S; Lewis, AL; Netti, PA1
Dufas, T; Eichler, K; Gruber-Rouh, T; Hammerstingl, R; Vogl, TJ; Zangos, S1
Ohishi, K; Ori, T; Sunayama, K; Takeda, M1
Fujiyama, Y; Kaneko, H; Kikuchi, M; Kinoshita, S; Nishizawa, T; Sakuno, T; Suzuki, H; Takahashi, M1
Chang, J; Wang, LZ; Zhang, YT; Zhong, XD1
Lam, VW; Laurence, JM; Richardson, AJ1
Cai, X; Cao, W; Ding, H; Liu, T; Wang, L; Wang, M; Xu, Q; Zhao, Z; Zhong, M; Zhou, X1
Chen, JS; Chou, WC; Hsu, HC; Liau, CT; Lin, YC; Shen, WC; Wu, CE; Yang, TS1
Dunne, DF; Fenwick, SW; Jones, RP; Malik, HZ; O'Grady, E; Poston, GJ; Smethurst, A; Stättner, S; Terlizzo, M1
Goi, T; Katayama, K; Koneri, K; Sawai, K; Yamaguchi, A1
Fischer von Weikersthal, L; Giessen, C; Heinemann, V; Laubender, RP; Modest, DP; Schalhorn, A; Schulz, C; Stintzing, S1
Fu, YL; Ge, FJ; Li, SS; Lin, L; Liu, JZ; Liu, LJ; Wang, Y; Xu, JM; Yao, K; Zhao, CH1
Burtness, B; Chun, YS; Cohen, SJ; Hall, MJ; Nagorney, DM; Sigurdson, ER; Thomay, AA; Truty, MJ1
Boige, V; Borget, I; Caramella, C; Dromain, C; Ducreux, M; Dumont, F; Elias, D; Farron, M; Goéré, D; Honoré, C; Malka, D; Pottier, E1
Capussotti, L; De Rosa, G; De Saussure, WO; Mentha, G; Rubbia-Brandt, L; Viganò, L1
Beeke, C; Bishnoi, S; Karapetis, CS; Maddern, G; Padbury, R; Padman, S; Price, TJ; Townsend, AR1
Besznyák, I; Bursics, A; Dede, K; Fekete, A; Kőszegi, G; Láng, I; Mersich, T; Mester, G; Pörneczi, B1
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Fukumoto, S; Habara, K; Iwasaki, T; Kamigaki, T; Ku, Y; Kunimoto, Y; Kuroda, Y; Nakamura, T; Nakamura, Y; Tamura, T1
Araki, Y; Hayashi, A; Ishibashi, N; Kishimoto, Y; Konishi, J; Matono, K; Mituoka, M; Miyagi, Y; Nakagawa, M; Nozoe, Y; Ogata, Y; Sasatomi, T; Shirouzu, K1
Gall, H; Giaccone, G; Gruia, G; Kedde, MA; Leisink, JM; Pinedo, HM; van der Vijgh, WJ; van Groeningen, CJ; van Riel, JM1
Boige, V; Ducreux, M; Taïeb, J1
Kosmas, C; Koufos, C; Tsavaris, N; Vadiaka, M1
Wagman, LD1
Bilchik, AJ; Chawla, SP; Chung, M; Foshag, LJ; Litvak, DA; Morton, DL; Ramming, KP; Tsioulias, GJ; Wood, TF1
Hacker, U; Heinemann, V; Schalhorn, A; Stemmler, J; Weise, A1
Chang, W; Kondo, Y; Kosaka, H; Maeda, S; Matsusaka, S; Okada, T; Oriyama, T1
Benchalal, M; Fingerhut, A; Fouere, S; Yahchouchy-Chouillard, E1
Dan, T; Kitayama, Y; Kosaka, H; Maeda, S; Matsusaka, S; Okada, T; Tanabe, H; Yamasaki, H1
Kono, A; Takeda, S1

Reviews

66 review(s) available for irinotecan and Cancer of Liver

ArticleYear
Hepatotoxicity following systemic therapy for colorectal liver metastases and the impact of chemotherapy-associated liver injury on outcomes after curative liver resection.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2017, Volume: 43, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Chemical and Drug Induced Liver Injury; Colorectal Neoplasms; Fluorouracil; Hepatectomy; Hepatic Veno-Occlusive Disease; Humans; Irinotecan; Liver Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Survival Rate

2017
Hepatic intra-arterial injection of irinotecan drug eluting beads (DEBIRI) for patients with unresectable colorectal liver metastases: A systematic review.
    Surgical oncology, 2017, Volume: 26, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Epidemiologic Methods; Humans; Injections, Intra-Arterial; Irinotecan; Liver Neoplasms; Microspheres

2017
Colorectal Cancer-Associated Spontaneous Tumor Lysis Syndrome: a Case Report and Review of the Current Literature.
    Journal of gastrointestinal cancer, 2019, Volume: 50, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Colon, Sigmoid; Colonoscopy; Fatal Outcome; Female; Humans; Irinotecan; Liver; Liver Neoplasms; Lymph Nodes; Lymphatic Metastasis; Middle Aged; Sigmoid Neoplasms; Time Factors; Tomography, X-Ray Computed; Tumor Lysis Syndrome

2019
Toward a better understanding of the mechanism of action for intra-arterial delivery of irinotecan from DC Bead
    Future oncology (London, England), 2019, Volume: 15, Issue:17

    Topics: Chemoembolization, Therapeutic; Clinical Trials as Topic; Colorectal Neoplasms; DNA Breaks, Single-Stranded; DNA Repair; DNA Replication; Drug Compounding; Drug Delivery Systems; Humans; Injections, Intra-Arterial; Irinotecan; Liver Neoplasms; Particle Size; Topoisomerase I Inhibitors; Treatment Outcome

2019
Transarterial chemoembolization with irinotecan beads in the treatment of colorectal liver metastases: systematic review.
    Journal of vascular and interventional radiology : JVIR, 2013, Volume: 24, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Disease Progression; Disease-Free Survival; Drug Carriers; Humans; Irinotecan; Liver Neoplasms; Quality of Life; Survival Analysis; Time Factors; Treatment Outcome

2013
[Carboplatin plus irinotecan induced partial response in a patient with small cell carcinoma of the prostate; a case report].
    Hinyokika kiyo. Acta urologica Japonica, 2014, Volume: 60, Issue:1

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Carboplatin; Carcinoma, Small Cell; Chemotherapy, Adjuvant; Creutzfeldt-Jakob Syndrome; Fatal Outcome; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Phosphopyruvate Hydratase; Prostate; Prostatic Neoplasms; Transurethral Resection of Prostate; Treatment Outcome

2014
Place of hepatic intra-arterial chemotherapy in the treatment of colorectal liver metastases.
    Journal of visceral surgery, 2014, Volume: 151 Suppl 1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Floxuridine; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Treatment Outcome

2014
A systematic review of salvage therapy to patients with metastatic colorectal cancer previously treated with fluorouracil, oxaliplatin and irinotecan +/- targeted therapy.
    Cancer treatment reviews, 2014, Volume: 40, Issue:6

    Topics: Alanine; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Databases, Factual; ErbB Receptors; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Molecular Targeted Therapy; Organoplatinum Compounds; Oxaliplatin; Phenylurea Compounds; PubMed; Pyridines; Retreatment; Salvage Therapy; Treatment Failure; Triazines

2014
[Case report of chemotherapeutic control of a gastric cancer producing granulocyte-colony stimulating factor].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2014, Volume: 111, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Combinations; Fatal Outcome; Gastroscopy; Granulocyte Colony-Stimulating Factor; Humans; Irinotecan; Liver Neoplasms; Male; Oxonic Acid; Stomach Neoplasms; Tegafur; Tomography, X-Ray Computed

2014
[A case of gastric small cell carcinoma with liver and lymph node metastases responding to CPT-11 plus CDDP chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Female; Humans; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Stomach Neoplasms; Treatment Outcome

2014
Primary combined small cell carcinoma and squamous cell carcinoma of the oropharynx with special reference to EGFR status of small cell carcinoma component: Case report and review of the literature.
    Auris, nasus, larynx, 2017, Volume: 44, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; ErbB Receptors; Fatal Outcome; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasms, Complex and Mixed; Oropharyngeal Neoplasms; Otorhinolaryngologic Surgical Procedures

2017
Intra-arterial therapies for colorectal cancer liver metastases (radioembolization excluded).
    Bulletin du cancer, 2017, Volume: 104, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Catheterization; Colorectal Neoplasms; Drug Carriers; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin

2017
Review of the Clinical Evidence for the Use of DEBIRI in the Treatment of Colorectal Metastatic Disease.
    Cardiovascular and interventional radiology, 2017, Volume: 40, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Humans; Irinotecan; Liver Neoplasms

2017
Drug-eluting particles for interventional pharmacology.
    Techniques in vascular and interventional radiology, 2007, Volume: 10, Issue:4

    Topics: Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Colorectal Neoplasms; Doxorubicin; Drug Carriers; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Microspheres

2007
[Current therapeutic options for liver metastasis].
    Revista medica de Chile, 2008, Volume: 136, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma; Catheter Ablation; Colorectal Neoplasms; Combined Modality Therapy; Cryosurgery; Floxuridine; Fluorouracil; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Neoplasm Staging; Prognosis; Survival Rate; Time Factors

2008
Regional chemotherapy for liver-limited metastatic colorectal cancer.
    Clinical colorectal cancer, 2008, Volume: 7, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Mitomycin; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin

2008
Yttrium-90 microsphere radioembolization for the treatment of liver malignancies: a structured meta-analysis.
    European radiology, 2009, Volume: 19, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Combined Modality Therapy; Fluorouracil; Glass; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Microspheres; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Treatment Outcome; Yttrium Radioisotopes

2009
Patterns of chemotherapy-induced hepatic injury and their implications for patients undergoing liver resection for colorectal liver metastases.
    Journal of hepato-biliary-pancreatic surgery, 2009, Volume: 16, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Fatty Liver; Floxuridine; Fluorouracil; Hepatectomy; Hepatic Veno-Occlusive Disease; Humans; Irinotecan; Leucovorin; Liver; Liver Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Risk Factors

2009
The role of capecitabine in the management of tumors of the digestive system.
    Reviews on recent clinical trials, 2009, Volume: 4, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Extrahepatic; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Cholangiocarcinoma; Colonic Neoplasms; Deoxycytidine; Digestive System Neoplasms; Docetaxel; Esophageal Neoplasms; Fluorouracil; Gallbladder Neoplasms; Humans; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Taxoids; Treatment Outcome; Vascular Endothelial Growth Factor A

2009
The European contribution to "Sugarbaker's protocol" for the treatment of colorectal peritoneal carcinomatosis.
    Revista espanola de enfermedades digestivas, 2009, Volume: 101, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Combined Modality Therapy; Europe; Fluorouracil; Humans; Hyperthermia, Induced; Infusions, Parenteral; Irinotecan; Liver Neoplasms; Multicenter Studies as Topic; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Peritoneal Neoplasms; Randomized Controlled Trials as Topic; Retrospective Studies; Salvage Therapy; Survival Rate; Treatment Outcome

2009
Secondary hepatic resection as a therapeutic goal in advanced colorectal cancer.
    World journal of gastroenterology, 2009, Aug-21, Volume: 15, Issue:31

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colorectal Neoplasms; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Survival Rate; Treatment Outcome

2009
Integration of neoadjuvant and adjuvant chemotherapy in patients with resectable liver metastases from colorectal cancer.
    Cancer treatment reviews, 2009, Volume: 35, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Chemotherapy, Cancer, Regional Perfusion; Colorectal Neoplasms; Fluorouracil; Hepatectomy; Humans; Infusions, Intravenous; Irinotecan; Leucovorin; Liver; Liver Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome

2009
[Hepatotoxicity of metastatic colorectal cancer chemotherapy: systematic review].
    Bulletin du cancer, 2010, Volume: 97, Issue:5

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colorectal Neoplasms; Fatty Liver; Hepatic Veno-Occlusive Disease; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Panitumumab

2010
Metastatic colorectal cancer: from improved survival to potential cure.
    Oncology, 2010, Volume: 78, Issue:3-4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Catheter Ablation; Colonic Neoplasms; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Male; Medical Oncology; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Time Factors; Treatment Outcome

2010
Consequences of chemotherapy on resection of colorectal liver metastases.
    Journal of visceral surgery, 2010, Volume: 147, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Chemical and Drug Induced Liver Injury; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Delivery Systems; Fatty Liver; Hepatectomy; Hepatic Veno-Occlusive Disease; Humans; Irinotecan; Liver Neoplasms; Liver Regeneration; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Postoperative Complications; Prognosis; Survival Rate; Tomography, X-Ray Computed

2010
Progress in metastatic colorectal cancer: growing role of cetuximab to optimize clinical outcome.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2010, Volume: 12, Issue:8

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Cetuximab; Colorectal Neoplasms; ErbB Receptors; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Vitamin B Complex

2010
Dual paraneoplastic syndromes: small cell lung carcinoma-related oncogenic osteomalacia, and syndrome of inappropriate antidiuretic hormone secretion: report of a case and review of the literature.
    Hawaii medical journal, 2011, Volume: 70, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Diabetes Mellitus, Type 2; Fatal Outcome; Gout; Humans; Hyperlipidemias; Hypertension; Hypophosphatemia; Inappropriate ADH Syndrome; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Osteomalacia; Paraneoplastic Syndromes; Risk Factors; Small Cell Lung Carcinoma

2011
[A case of gastric neuroendocrine cell carcinoma successfully treated by neoadjuvant chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Carcinoma, Neuroendocrine; Cisplatin; Humans; Irinotecan; Liver Neoplasms; Lymph Node Excision; Male; Neoadjuvant Therapy; Stomach Neoplasms

2011
[A case of irinotecan or panitumumab-induced interstitial pneumonia successfully treated by steroid pulse therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:2

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Diseases, Interstitial; Male; Methylprednisolone; Middle Aged; Organoplatinum Compounds; Panitumumab; Tomography, X-Ray Computed

2012
Cetuximab in metastatic colorectal cancer.
    Expert review of anticancer therapy, 2012, Volume: 12, Issue:5

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; ErbB Receptors; Humans; Irinotecan; Liver Neoplasms; Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins

2012
Relapsed hepatoblastoma.
    Pediatric blood & cancer, 2012, Volume: 59, Issue:5

    Topics: Camptothecin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Doxorubicin; Hepatoblastoma; Humans; Irinotecan; Liver Neoplasms; Neoplasm Recurrence, Local; Radiotherapy; Stem Cell Transplantation; Transplantation, Homologous

2012
Chemotherapeutic approaches for newly diagnosed hepatoblastoma: past, present, and future strategies.
    Pediatric blood & cancer, 2012, Volume: 59, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Hepatoblastoma; Humans; Infant; Irinotecan; Liver Neoplasms; Male; Neoplasm Metastasis; Risk Factors; Survival Rate; Transplantation, Homologous

2012
Treatment with bevacizumab and FOLFOXIRI in patients with advanced colorectal cancer: presentation of two novel trials (CHARTA and PERIMAX) and review of the literature.
    BMC cancer, 2012, Aug-16, Volume: 12

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Disease-Free Survival; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Multicenter Studies as Topic; Organoplatinum Compounds; Randomized Controlled Trials as Topic

2012
Advances in the treatment of metastatic colorectal cancer.
    Clinical colorectal cancer, 2001, Volume: 1, Issue:1

    Topics: Administration, Oral; Antibodies, Monoclonal; Antineoplastic Agents; Camptothecin; Cancer Vaccines; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Administration Schedule; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Prodrugs; Quinazolines; Randomized Controlled Trials as Topic; Thiophenes; Uracil

2001
[A case of AFP-producing gastric cancer with multiple liver metastases responding to CPT-11 and cisplatin combination chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:11

    Topics: Adenocarcinoma; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Administration Schedule; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Stomach Neoplasms

2002
The combination of capecitabine and oxaliplatin in metastatic colorectal cancer.
    Clinical colorectal cancer, 2003, Volume: 2, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Organoplatinum Compounds; Oxaliplatin

2003
Palliative treatment of patients with colorectal cancer.
    Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society, 2003, Volume: 92, Issue:1

    Topics: Antimetabolites, Antineoplastic; Camptothecin; Colorectal Neoplasms; Disease Progression; Enzyme Inhibitors; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Palliative Care; Quinazolines; Survival Analysis; Tegafur; Thiophenes; Thymidylate Synthase; Topoisomerase I Inhibitors; Treatment Outcome; Uracil

2003
Induction therapy in patients with metastatic colorectal cancer.
    Seminars in oncology, 2003, Volume: 30, Issue:4 Suppl 12

    Topics: Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin

2003
Review article: colorectal cancer chemotherapy.
    Alimentary pharmacology & therapeutics, 2003, Oct-01, Volume: 18, Issue:7

    Topics: Antineoplastic Agents; Camptothecin; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colorectal Neoplasms; Drug Design; Floxuridine; Fluorouracil; Forecasting; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Pyrimidines; Quinazolines; Thiophenes

2003
[Application and problems in hepatic arterial infusion chemotherapy].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7

    Topics: Antineoplastic Agents; Camptothecin; Cisplatin; Colorectal Neoplasms; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Interleukin-2; Irinotecan; Liver Neoplasms; Neoadjuvant Therapy

2003
[Home chemotherapy and outpatient treatment for metastatic colorectal cancer].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7

    Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Fatal Outcome; Female; Fluorouracil; Home Care Services; Humans; Infusions, Intravenous; Irinotecan; Levamisole; Liver Neoplasms; Middle Aged; Quality of Life

2003
[Guidance and informed consent in colon cancer therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colectomy; Colorectal Neoplasms; Fluorouracil; Humans; Informed Consent; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Neoplasm Recurrence, Local

2003
[Treatment of metastatic liver carcinoma: chemotherapy and immunotherapy].
    Nihon Geka Gakkai zasshi, 2003, Volume: 104, Issue:10

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Fluorouracil; Humans; Irinotecan; Liver Neoplasms

2003
[Chemotherapy for colorectal carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Prospective Studies; Randomized Controlled Trials as Topic; Tegafur; Uracil

2003
First-line treatment strategies to improve survival in patients with advanced colorectal cancer.
    Drugs, 2004, Volume: 64, Issue:1

    Topics: Antineoplastic Agents; Camptothecin; Clinical Trials as Topic; Colorectal Neoplasms; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Survival Rate

2004
Systemic treatment of advanced colorectal carcinoma.
    European journal of gastroenterology & hepatology, 2004, Volume: 16, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Chemotherapy, Adjuvant; Colorectal Neoplasms; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Pyrimidines; Treatment Outcome

2004
Current strategies in previously untreated advanced colorectal cancer.
    Oncology (Williston Park, N.Y.), 2004, Volume: 18, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin

2004
Recent phase III trials of fluorouracil, irinotecan, and oxaliplatin as chemotherapy for metastatic colorectal cancer.
    Cancer chemotherapy and pharmacology, 2004, Volume: 54 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin

2004
New options and old dilemmas in the treatment of patients with advanced colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2004, Volume: 15, Issue:10

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Humans; Irinotecan; Liver Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Signal Transduction

2004
[Recent results of irinotecan therapy in colorectal cancer].
    Magyar onkologia, 2004, Volume: 48, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Survival Analysis; Treatment Outcome

2004
Pharmacogenomics of fluorouracil, irinotecan, and oxaliplatin in hepatic metastases of colorectal cancer: clinical implications.
    American journal of pharmacogenomics : genomics-related research in drug development and clinical practice, 2005, Volume: 5, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Pharmacogenetics

2005
Combination of gemcitabine and irinotecan for recurrent metastatic osteogenic sarcoma.
    Clinical advances in hematology & oncology : H&O, 2005, Volume: 3, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Cisplatin; Combined Modality Therapy; Deoxycytidine; Doxorubicin; Etoposide; Femoral Neoplasms; Gemcitabine; Head and Neck Neoplasms; Humans; Ifosfamide; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoadjuvant Therapy; Osteosarcoma; Palliative Care; Salvage Therapy; Scalp; Skin Neoplasms; Thoracotomy

2005
Treatment of hepatic metastases from colorectal cancer: many doubts, some certainties.
    Cancer treatment reviews, 2006, Volume: 32, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Catheter Ablation; Chemotherapy, Adjuvant; Colorectal Neoplasms; Cryosurgery; Decision Trees; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Prognosis; Risk Factors; Treatment Failure; Treatment Outcome

2006
[The modern treatment of colorectal cancer. Present and future].
    Orvosi hetilap, 2006, Mar-05, Volume: 147, Issue:9

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Fluorouracil; Humans; Immunologic Factors; Infusions, Intravenous; Injections, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin

2006
Adjuvant therapy for colorectal cancer: yesterday, today, and tomorrow.
    Oncology (Williston Park, N.Y.), 2006, Volume: 20, Issue:5

    Topics: Administration, Oral; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Camptothecin; Cetuximab; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Therapy, Combination; Fluorouracil; History, 20th Century; History, 21st Century; Humans; Infusions, Intravenous; Injections, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Patient Selection; Randomized Controlled Trials as Topic

2006
[Hepatic arterial infusion chemotherapy for liver metastases from digestive cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colorectal Neoplasms; Drug Administration Schedule; Drug Combinations; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Oxonic Acid; Tegafur

2006
[Pre-operative chemotherapy for patients with hepatic metastases from colorectal cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2007, Volume: 29, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Survival Analysis

2007
Hepatic complications following preoperative chemotherapy with oxaliplatin or irinotecan for hepatic colorectal metastases.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2008, Volume: 34, Issue:6

    Topics: Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Fatty Liver; Hepatectomy; Hepatic Veno-Occlusive Disease; Humans; Irinotecan; Liver Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin

2008
[Angiogenesis targeting in gastro-intestinal cancers].
    Bulletin du cancer, 2007, Volume: 94, Issue:7 Suppl

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Carcinoma, Hepatocellular; Colorectal Neoplasms; Esophageal Neoplasms; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Neovascularization, Pathologic; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Stomach Neoplasms

2007
Treatment of advanced colorectal cancer in the elderly.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2007, Volume: 33 Suppl 2

    Topics: Age Factors; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Colectomy; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Stents

2007
Advances in neoadjuvant therapy for colorectal cancer with liver metastases.
    Cancer treatment reviews, 2008, Volume: 34, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Clinical Trials as Topic; Colorectal Neoplasms; Combined Modality Therapy; Fluorouracil; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin

2008
[Treatment of recurrent gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Doxorubicin; Drug Administration Schedule; Epirubicin; Etoposide; Fluorouracil; Humans; Immunologic Factors; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Methotrexate; Mitomycin; Neoplastic Cells, Circulating; Peritoneal Neoplasms; Stomach Neoplasms

1998
Is repeated treatment with a 5-fluorouracil-based regimen useful in colorectal cancer?
    Seminars in oncology, 1998, Volume: 25, Issue:5 Suppl 11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Floxuridine; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Injections, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Randomized Controlled Trials as Topic; Salvage Therapy

1998
Therapeutic options for the treatment of colorectal cancer following 5-fluorouracil failure.
    Seminars in oncology, 1998, Volume: 25, Issue:5 Suppl 11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Clinical Trials as Topic; Colorectal Neoplasms; Cryosurgery; Embolization, Therapeutic; Fluorouracil; Hepatectomy; Humans; Infusions, Intra-Arterial; Injections, Intralesional; Irinotecan; Liver Neoplasms; Topoisomerase I Inhibitors; Treatment Failure; Trimetrexate

1998
Irinotecan (CPT-11) induced colitis: report of a case and review of Food and Drug Administration MEDWATCH reporting.
    Gastrointestinal endoscopy, 1999, Volume: 50, Issue:6

    Topics: Adenocarcinoma; Adverse Drug Reaction Reporting Systems; Antineoplastic Agents, Phytogenic; Camptothecin; Chemotherapy, Adjuvant; Colitis; Colonoscopy; Female; Gastrointestinal Hemorrhage; Humans; Intestinal Mucosa; Irinotecan; Liver Neoplasms; Middle Aged; Neoplasm Staging; Sigmoid Neoplasms; United States; United States Food and Drug Administration

1999
[The new chemotherapy of colorectal cancers].
    Presse medicale (Paris, France : 1983), 2002, Jan-26, Volume: 31, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Combined Modality Therapy; Deoxycytidine; Drug Therapy, Combination; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Postoperative Care; Prodrugs; Quinazolines; Randomized Controlled Trials as Topic; Thiophenes; Time Factors

2002

Trials

146 trial(s) available for irinotecan and Cancer of Liver

ArticleYear
Radioembolization With Chemotherapy for Colorectal Liver Metastases: A Randomized, Open-Label, International, Multicenter, Phase III Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021, 12-10, Volume: 39, Issue:35

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Case-Control Studies; Chemoradiotherapy; Colorectal Neoplasms; Embolization, Therapeutic; Female; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Oxaliplatin; Prognosis; Survival Rate; Yttrium Radioisotopes

2021
Study protocol of an open-label, single arm phase II trial investigating the efficacy, safety and quality of life of neoadjuvant chemotherapy with liposomal irinotecan combined with Oxaliplatin and 5-fluorouracil/Folinic acid followed by curative surgical
    BMC cancer, 2021, Nov-18, Volume: 21, Issue:1

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Female; Fluorouracil; Germany; Humans; Irinotecan; Leucovorin; Liposomes; Liver Neoplasms; Male; Neoadjuvant Therapy; Oxaliplatin; Pancreatic Neoplasms; Progression-Free Survival; Quality of Life

2021
Drug-Eluting Bead, Irinotecan Therapy of Unresectable Intrahepatic Cholangiocarcinoma (DELTIC) with Concomitant Systemic Gemcitabine and Cisplatin.
    Annals of surgical oncology, 2022, Volume: 29, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Camptothecin; Cholangiocarcinoma; Cisplatin; Deoxycytidine; Gemcitabine; Humans; Irinotecan; Liver Neoplasms; Prospective Studies; Treatment Outcome

2022
FOLFOXIRI Plus Panitumumab As First-Line Treatment of
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019, 12-10, Volume: 37, Issue:35

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Case-Control Studies; Colorectal Neoplasms; Female; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Mutation; Oxaliplatin; Panitumumab; Prognosis; ras Proteins; Survival Rate

2019
Liposomal Irinotecan + 5-FU/LV in Metastatic Pancreatic Cancer: Subgroup Analyses of Patient, Tumor, and Previous Treatment Characteristics in the Pivotal NAPOLI-1 Trial.
    Pancreas, 2020, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Humans; Irinotecan; Kaplan-Meier Estimate; Leucovorin; Liposomes; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Treatment Outcome

2020
Association Between Baseline Circulating Tumor Cells, Molecular Tumor Profiling, and Clinical Characteristics in a Large Cohort of Chemo-naïve Metastatic Colorectal Cancer Patients Prospectively Collected.
    Clinical colorectal cancer, 2020, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Bone Neoplasms; Camptothecin; Cell Count; Colorectal Neoplasms; DNA Mutational Analysis; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Microsatellite Instability; Middle Aged; Mutation; Neoplasm Staging; Neoplastic Cells, Circulating; Organoplatinum Compounds; Oxaliplatin; Prognosis; Progression-Free Survival; Prospective Studies; Proto-Oncogene Proteins B-raf; ras Proteins; Risk Assessment; Young Adult

2020
BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial.
    Nature medicine, 2020, Volume: 26, Issue:6

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; CD8-Positive T-Lymphocytes; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Lymphocytes, Tumor-Infiltrating; Male; Middle Aged; Myeloid-Derived Suppressor Cells; Pancreatic Neoplasms; Peptides; Peritoneal Neoplasms; Receptors, CXCR4; Retroperitoneal Neoplasms; Survival Rate; T-Lymphocytes, Regulatory; Treatment Outcome

2020
Intra-arterial hepatic beads loaded with irinotecan (DEBIRI) with mFOLFOX6 in unresectable liver metastases from colorectal cancer: a Phase 2 study.
    British journal of cancer, 2020, Volume: 123, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoembolization, Therapeutic; Colorectal Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Survival Analysis; Treatment Outcome

2020
Morphologic response to chemotherapy containing bevacizumab in patients with colorectal liver metastases: A post hoc analysis of the WJOG4407G phase III study.
    Medicine, 2020, Sep-04, Volume: 99, Issue:36

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Female; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Japan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Oxaliplatin; Predictive Value of Tests; Prognosis; Progression-Free Survival; Response Evaluation Criteria in Solid Tumors; Tomography, X-Ray Computed; Topoisomerase I Inhibitors; Treatment Outcome; Vitamin B Complex

2020
Effects of Protein and Calorie Restriction on the Metabolism and Toxicity Profile of Irinotecan in Cancer Patients.
    Clinical pharmacology and therapeutics, 2021, Volume: 109, Issue:5

    Topics: Aged; Caloric Restriction; Diarrhea; Diet, Protein-Restricted; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neutropenia

2021
Early weight loss is an independent risk factor for shorter survival and increased side effects in patients with metastatic colorectal cancer undergoing first-line treatment within the randomized Phase III trial FIRE-3 (AIO KRK-0306).
    International journal of cancer, 2022, 01-01, Volume: 150, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Prognosis; Prospective Studies; Retrospective Studies; Risk Factors; Survival Rate; Weight Loss

2022
Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228).
    British journal of cancer, 2017, Sep-26, Volume: 117, Issue:7

    Topics: Administration, Intravenous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arylamine N-Acetyltransferase; ATP Binding Cassette Transporter, Subfamily B; Camptothecin; Catecholamine Plasma Membrane Transport Proteins; Cetuximab; Colorectal Neoplasms; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Diarrhea; Disease-Free Survival; Female; Fluorouracil; Glucuronosyltransferase; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neutropenia; Organoplatinum Compounds; Oxaliplatin; Pharmacogenetics; Polymorphism, Single Nucleotide; Survival Rate; Treatment Outcome; Vitamin K Epoxide Reductases

2017
Genomic predictors of chemotherapy efficacy in advanced or recurrent gastric cancer in the GC0301/TOP002 phase III clinical trial.
    Cancer letters, 2018, 01-01, Volume: 412

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Combinations; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Stomach Neoplasms; Tegafur; Wnt-5a Protein

2018
Prospective phase II trial of combination hepatic artery infusion and systemic chemotherapy for unresectable colorectal liver metastases: Long term results and curative potential.
    Journal of surgical oncology, 2018, Volume: 117, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Deoxyuridine; Disease-Free Survival; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Survival Rate; Treatment Outcome

2018
AMALTHEA: Prospective, Single-Arm Study of the Hellenic Cooperative Oncology Group (HeCOG) Evaluating Efficacy and Safety of First-Line FOLFIRI + Aflibercept for 6 Months Followed by Aflibercept Maintenance in Patients With Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2018, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Oxaliplatin; Prognosis; Prospective Studies; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Survival Rate; Young Adult

2018
FOLFIRINOX as induction treatment in rectal cancer patients with synchronous metastases: Results of the FFCD 1102 phase II trial.
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 104

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fatigue; Female; Fluorouracil; Follow-Up Studies; Gastrointestinal Diseases; Hematologic Diseases; Humans; Irinotecan; Kaplan-Meier Estimate; Leucovorin; Liver Neoplasms; Lung Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Oxaliplatin; Paresthesia; Progression-Free Survival; Rectal Neoplasms; Remission Induction; Tomography, X-Ray Computed; Treatment Outcome

2018
Total cell-free DNA, carcinoembryonic antigen, and C-reactive protein for assessment of prognosis in patients with metastatic colorectal cancer.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2018, Volume: 40, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; C-Reactive Protein; Carcinoembryonic Antigen; Case-Control Studies; Cell-Free Nucleic Acids; Cetuximab; Cohort Studies; Colorectal Neoplasms; Denmark; Everolimus; Female; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Prognosis; Survival Rate; Young Adult

2018
Phase II Randomized Trial of Sequential or Concurrent FOLFOXIRI-Bevacizumab Versus FOLFOX-Bevacizumab for Metastatic Colorectal Cancer (STEAM).
    The oncologist, 2019, Volume: 24, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Oxaliplatin; Prognosis; Survival Rate; Young Adult

2019
Tumor calcification as a prognostic factor in cetuximab plus chemotherapy-treated patients with metastatic colorectal cancer.
    Anti-cancer drugs, 2019, Volume: 30, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Calcinosis; Cetuximab; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Oxaliplatin; Prognosis; Retrospective Studies; Survival Rate

2019
NAPOLI-1 phase 3 study of liposomal irinotecan in metastatic pancreatic cancer: Final overall survival analysis and characteristics of long-term survivors.
    European journal of cancer (Oxford, England : 1990), 2019, Volume: 108

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Carcinoma, Pancreatic Ductal; Female; Fluorouracil; Humans; Irinotecan; Karnofsky Performance Status; Leucovorin; Liposomes; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Progression-Free Survival; Proportional Hazards Models

2019
MINOAS: A Single-arm Translational Phase II Trial of FOLFIRI Plus Aflibercept as First-line Therapy in Unresectable, Metastatic Colorectal Cancer.
    Targeted oncology, 2019, Volume: 14, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Prognosis; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Survival Rate

2019
A phase 2 study of panitumumab with irinotecan as salvage therapy in chemorefractory KRAS exon 2 wild-type metastatic colorectal cancer patients.
    British journal of cancer, 2019, Volume: 121, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amphiregulin; Antineoplastic Combined Chemotherapy Protocols; Asthenia; Colorectal Neoplasms; Diarrhea; Drug Eruptions; Epiregulin; ErbB Receptors; Female; GTP Phosphohydrolases; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Magnesium; Male; Membrane Proteins; Middle Aged; Panitumumab; Peritoneal Neoplasms; Progression-Free Survival; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); PTEN Phosphohydrolase; Salvage Therapy; Survival Rate; Treatment Outcome; Water-Electrolyte Imbalance

2019
Selective TACE with irinotecan-loaded 40 μm microspheres and FOLFIRI for colorectal liver metastases: phase I dose escalation pharmacokinetic study.
    BMC cancer, 2019, Aug-01, Volume: 19, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoembolization, Therapeutic; Cohort Studies; Colorectal Neoplasms; Drug Dosage Calculations; Feasibility Studies; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Microspheres; Middle Aged; Prospective Studies; Survival Analysis

2019
A randomized, placebo-controlled phase 2 study of ganitumab or conatumumab in combination with FOLFIRI for second-line treatment of mutant KRAS metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Double-Blind Method; Female; Fluorouracil; Genotype; Humans; Insulin-Like Growth Factor Binding Proteins; Irinotecan; Kaplan-Meier Estimate; Leucovorin; Liver Neoplasms; Male; Middle Aged; Proportional Hazards Models; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Receptors, IgG; Treatment Outcome

2013
Hepatic activation of irinotecan predicts tumour response in patients with colorectal liver metastases treated with DEBIRI: exploratory findings from a phase II study.
    Cancer chemotherapy and pharmacology, 2013, Volume: 72, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Biotransformation; Blotting, Western; Camptothecin; Colorectal Neoplasms; DNA, Neoplasm; Drug Delivery Systems; Genotype; Glucuronosyltransferase; Humans; Irinotecan; Liver; Liver Neoplasms; Mass Spectrometry; Microsomes; Neoplasm Proteins; Prospective Studies; Reproducibility of Results

2013
Hepatic arterial infusion with irinotecan in patients with liver metastases of colorectal cancer: results of an extended phase I study.
    Chemotherapy, 2013, Volume: 59, Issue:1

    Topics: Aged; Agranulocytosis; Antineoplastic Agents, Phytogenic; Camptothecin; Cohort Studies; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Injections, Intra-Arterial; Irinotecan; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Survival Analysis; Tomography, X-Ray Computed

2013
Radiological assessment of response to neoadjuvant transcatheter hepatic therapy with irinotecan-eluting beads (DEBIRI(®)) for colorectal liver metastases does not predict tumour destruction or long-term outcome.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2013, Volume: 39, Issue:10

    Topics: Adult; Aged; Angiography; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Contrast Media; Disease Progression; Drug Delivery Systems; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Tomography, X-Ray Computed; Treatment Outcome

2013
Evaluation of prognostic factors in liver-limited metastatic colorectal cancer: a preplanned analysis of the FIRE-1 trial.
    British journal of cancer, 2013, Sep-17, Volume: 109, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Prognosis; Proportional Hazards Models; Survival Analysis; Young Adult

2013
Bifractionated CPT-11 with LV5FU2 infusion (FOLFIRI-3) in combination with bevacizumab: clinical outcomes in first-line metastatic colorectal cancers according to plasma angiopoietin-2 levels.
    BMC cancer, 2013, Dec-27, Volume: 13

    Topics: Adult; Aged; Aged, 80 and over; Angiopoietin-2; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Colorectal Neoplasms; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Fluorouracil; Humans; Irinotecan; Kaplan-Meier Estimate; Leucovorin; Liver Neoplasms; Middle Aged; Treatment Outcome

2013
Phase II trial of hepatic artery infusional and systemic chemotherapy for patients with unresectable hepatic metastases from colorectal cancer: conversion to resection and long-term outcomes.
    Annals of surgery, 2015, Volume: 261, Issue:2

    Topics: Adult; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Floxuridine; Fluorouracil; Follow-Up Studies; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Survival Analysis; Treatment Outcome

2015
Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis: the New EPOC randomised controlled trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:6

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Proportional Hazards Models; Treatment Outcome

2014
Vincristine and irinotecan in children with relapsed hepatoblastoma: a single-institution experience.
    Pediatric hematology and oncology, 2015, Volume: 32, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Child, Preschool; Disease-Free Survival; Hepatoblastoma; Humans; Infant; Irinotecan; Liver Neoplasms; Liver Transplantation; Neoplasm Recurrence, Local; Survival Rate; Time Factors; Vincristine

2015
Phase II trial of cetuximab plus irinotecan for oxaliplatin- and irinotecan-based chemotherapy-refractory patients with advanced and/or metastatic colorectal cancer: evaluation of efficacy and safety based on KRAS mutation status (T-CORE0801).
    Oncology, 2014, Volume: 87, Issue:1

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Class I Phosphatidylinositol 3-Kinases; Colorectal Neoplasms; Disease-Free Survival; DNA Mutational Analysis; Female; GTP Phosphohydrolases; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Lung Neoplasms; Male; Membrane Proteins; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); ras Proteins; Treatment Outcome

2014
Dose escalating study of cetuximab and 5-FU/folinic acid (FA)/oxaliplatin/irinotecan (FOLFOXIRI) in first line therapy of patients with metastatic colorectal cancer.
    BMC cancer, 2014, Jul-19, Volume: 14

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Maximum Tolerated Dose; Organoplatinum Compounds; Oxaliplatin; Treatment Outcome

2014
Bevacizumab plus mFOLFOX-6 or FOLFOXIRI in patients with initially unresectable liver metastases from colorectal cancer: the OLIVIA multinational randomised phase II trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Survival Rate

2015
Bevacizumab continuation versus no continuation after first-line chemotherapy plus bevacizumab in patients with metastatic colorectal cancer: a randomized phase III non-inferiority trial (SAKK 41/06).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Prospective Studies; Survival Rate; Young Adult

2015
Acute small-bowel toxicity during neoadjuvant combined radiochemotherapy in locally advanced rectal cancer: determination of optimal dose-volume cut-off value predicting grade 2-3 diarrhoea.
    Radiation oncology (London, England), 2015, Jan-31, Volume: 10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Chemoradiotherapy; Diarrhea; Female; Follow-Up Studies; Humans; Intestine, Small; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Prognosis; Prospective Studies; Radiation Injuries; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Rectal Neoplasms

2015
Circulating Tumor Cell Enumeration in a Phase II Trial of a Four-Drug Regimen in Advanced Colorectal Cancer.
    Clinical colorectal cancer, 2015, Volume: 14, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Neoplastic Cells, Circulating; Organoplatinum Compounds; Oxaliplatin; Prognosis; Prospective Studies; Survival Rate

2015
Trans-Arterial Chemoembolization with Irinotecan-Loaded Drug-Eluting Beads (DEBIRI) and Capecitabine in Refractory Liver Prevalent Colorectal Metastases: A Phase II Single-Center Study.
    Cardiovascular and interventional radiology, 2015, Volume: 38, Issue:6

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; Chemoembolization, Therapeutic; Colorectal Neoplasms; Disease-Free Survival; Drug Delivery Systems; Feasibility Studies; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Treatment Outcome

2015
Histological response, pattern of tumor destruction and clinical outcome after neoadjuvant chemotherapy including bevacizumab or cetuximab in patients undergoing liver resection for colorectal liver metastases.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2015, Volume: 41, Issue:7

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Kaplan-Meier Estimate; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Necrosis; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Proportional Hazards Models; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Tomography, X-Ray Computed; Treatment Outcome

2015
Endostar combined with irinotecan/calcium folinate/5-fluorouracil (FOLFIRI) for treating advanced colorectal cancer: A clinical study.
    Journal of chemotherapy (Florence, Italy), 2015, Volume: 27, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Endostatins; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Prognosis; Recombinant Proteins; Survival Rate

2015
SPIRITT: A Randomized, Multicenter, Phase II Study of Panitumumab with FOLFIRI and Bevacizumab with FOLFIRI as Second-Line Treatment in Patients with Unresectable Wild Type KRAS Metastatic Colorectal Cancer.
    Clinical colorectal cancer, 2015, Volume: 14, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; ErbB Receptors; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Panitumumab; Prognosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Salvage Therapy; Survival Rate

2015
Dose-finding study of hepatic arterial infusion of irinotecan-based treatment in patients with advanced cancers metastatic to the liver.
    Investigational new drugs, 2015, Volume: 33, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Organoplatinum Compounds; Oxaliplatin

2015
Randomized controlled trial of irinotecan drug-eluting beads with simultaneous FOLFOX and bevacizumab for patients with unresectable colorectal liver-limited metastasis.
    Cancer, 2015, Oct-15, Volume: 121, Issue:20

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Drug Delivery Systems; Fluorouracil; Hepatic Artery; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Treatment Outcome

2015
Conversion to resection of liver metastases from colorectal cancer with hepatic artery infusion of combined chemotherapy and systemic cetuximab in multicenter trial OPTILIV.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Proto-Oncogene Proteins p21(ras); Treatment Outcome

2016
High Resectability Rate of Initially Unresectable Colorectal Liver Metastases After UGT1A1-Adapted High-Dose Irinotecan Combined with LV5FU2 and Cetuximab: A Multicenter Phase II Study (ERBIFORT).
    Annals of surgical oncology, 2016, Volume: 23, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Glucuronosyltransferase; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Prognosis; Survival Rate

2016
Final analysis of a phase II study of modified FOLFIRINOX in locally advanced and metastatic pancreatic cancer.
    British journal of cancer, 2016, Mar-29, Volume: 114, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Peritoneal Neoplasms; Prognosis; Prospective Studies; Survival Rate

2016
Plasma ceramide, a real-time predictive marker of pulmonary and hepatic metastases response to stereotactic body radiation therapy combined with irinotecan.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2016, Volume: 119, Issue:2

    Topics: Adult; Aged; Biomarkers; Camptothecin; Ceramides; Combined Modality Therapy; Female; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Radiation-Sensitizing Agents; Radiosurgery; Treatment Outcome

2016
Pharmacokinetics of Irinotecan, Oxaliplatin and 5-Fluorouracil During Hepatic Artery Chronomodulated Infusion: A Translational European OPTILIV Study.
    Clinical pharmacokinetics, 2017, Volume: 56, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Chronotherapy; Europe; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin

2017
Patterns of progression, treatment of progressive disease and post-progression survival in the New EPOC study.
    British journal of cancer, 2016, Aug-09, Volume: 115, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Cetuximab; Colorectal Neoplasms; Disease Progression; Disease-Free Survival; Female; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Metastasectomy; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin

2016
PARAGON II - A single arm multicentre phase II study of neoadjuvant therapy using irinotecan bead in patients with resectable liver metastases from colorectal cancer.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2016, Volume: 42, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Disease-Free Survival; Female; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Metastasectomy; Microspheres; Middle Aged; Neoadjuvant Therapy; Treatment Outcome

2016
Phase II study of UFT with leucovorin plus hepatic arterial infusion with irinotecan, 5-fluorouracil and leucovorin for non-resectable liver metastases of colorectal cancer.
    Chemotherapy, 2009, Volume: 55, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Tegafur; Uracil

2009
Phase I and pharmacokinetic study of tegafur-uracil/leucovorin combined with 5-fluorouracil/leucovorin and irinotecan in patients with advanced colorectal cancer.
    American journal of clinical oncology, 2009, Volume: 32, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Survival Rate; Tegafur; Tissue Distribution; Treatment Outcome

2009
Phase I/II study of twenty-four-hour infusion of irinotecan in combination with oral UFT plus leucovorin for metastatic colorectal cancer.
    Oncology, 2009, Volume: 76, Issue:5

    Topics: Adenocarcinoma; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Peritoneal Neoplasms; Prognosis; Survival Rate; Tegafur; Treatment Outcome; Young Adult

2009
Capecitabine plus Irinotecan (XELIRI regimen) compared to 5-FU/LV plus Irinotecan (FOLFIRI regimen) as neoadjuvant treatment for patients with unresectable liver-only metastases of metastatic colorectal cancer: a randomised prospective phase II trial.
    BMC cancer, 2009, Apr-22, Volume: 9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Diarrhea; Fatigue; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Nausea; Neoadjuvant Therapy; Neutropenia; Prospective Studies; Survival Analysis; Treatment Outcome

2009
A phase II experience with neoadjuvant irinotecan (CPT-11), 5-fluorouracil (5-FU) and leucovorin (LV) for colorectal liver metastases.
    BMC cancer, 2009, May-20, Volume: 9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cohort Studies; Colorectal Neoplasms; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Metastasis; Treatment Outcome

2009
A randomized phase III study comparing adjuvant 5-fluorouracil/folinic acid with FOLFIRI in patients following complete resection of liver metastases from colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Patient Compliance; Treatment Outcome

2009
Treatment of fluorouracil-refractory patients with liver metastases from colorectal cancer by using yttrium-90 resin microspheres plus concomitant systemic irinotecan chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Australia; Brachytherapy; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Male; Maximum Tolerated Dose; Microspheres; Middle Aged; Radiopharmaceuticals; Radiotherapy, Adjuvant; Time Factors; Topoisomerase I Inhibitors; Treatment Outcome; Yttrium Isotopes

2009
A model of primary culture of colorectal cancer and liver metastasis to predict chemosensitivity.
    The Journal of surgical research, 2011, Volume: 166, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Culture Techniques; Cell Division; Colorectal Neoplasms; Drug Monitoring; Drug Resistance, Neoplasm; HT29 Cells; Humans; Irinotecan; Ki-67 Antigen; Liver Neoplasms; Polyhydroxyethyl Methacrylate; Radiography; Topoisomerase I Inhibitors

2011
[Efficacy of FORFIRI regimen on oxaliplatin-based chemotherapy-failed advanced colorectal cancer].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Disease Progression; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasm Staging; Neutropenia; Rectal Neoplasms; Remission Induction; Salvage Therapy; Survival Rate; Vomiting; Young Adult

2009
A phase II study of irinotecan and capecitabine for patients with unresectable liver-only metastases from colorectal cancer.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged

2010
Phase II trial of irinotecan, carboplatin, and bevacizumab in the treatment of patients with extensive-stage small-cell lung cancer.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2009, Volume: 4, Issue:12

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bone Neoplasms; Camptothecin; Carboplatin; Female; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prognosis; Small Cell Lung Carcinoma; Survival Rate; Treatment Outcome

2009
Transarterial chemoembolisation (TACE) using irinotecan-loaded beads for the treatment of unresectable metastases to the liver in patients with colorectal cancer: an interim report.
    World journal of surgical oncology, 2009, Nov-03, Volume: 7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Humans; Irinotecan; Liver Neoplasms; Male; Microspheres; Middle Aged; Prospective Studies; Registries; Treatment Outcome

2009
Irinotecan plus carboplatin in patients with extensive-disease small-cell lung cancer.
    Medical oncology (Northwood, London, England), 2011, Volume: 28, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Camptothecin; Carboplatin; Disease Progression; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Small Cell Lung Carcinoma; Treatment Outcome

2011
Phase II randomized study of two regimens of sequentially administered mitomycin C and irinotecan in patients with unresectable esophageal and gastroesophageal adenocarcinoma.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2010, Volume: 5, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Carcinoma, Squamous Cell; Esophageal Neoplasms; Esophagogastric Junction; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Neoplasm Staging; Stomach Neoplasms; Survival Rate; Treatment Outcome

2010
Chemotherapy: How useful is adjuvant irinotecan in stage IV CRC?
    Nature reviews. Clinical oncology, 2010, Volume: 7, Issue:4

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Confidence Intervals; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Survival Analysis; Vitamin B Complex

2010
Triplet schedule of weekly 5-fluorouracil and alternating irinotecan or oxaliplatin in advanced colorectal cancer: a dose-finding and phase II study.
    Oncology reports, 2010, Volume: 23, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Survival Rate; Treatment Outcome

2010
Phase II study of sequential triplet chemotherapy, irinotecan and cisplatin followed by amrubicin, in patients with extensive-stage small cell lung cancer: West Japan Thoracic Oncology Group Study 0301.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2010, Volume: 5, Issue:7

    Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Camptothecin; Cisplatin; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Small Cell Lung Carcinoma; Survival Rate; Treatment Outcome; Young Adult

2010
Phase I/II study of irinotecan, UFT and leucovorin with hepatic arterial infusion using 5-FU in colorectal cancer patients with unresectable liver metastases.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Survival Rate; Tegafur; Treatment Outcome; Uracil

2011
Toxicity of irinotecan-eluting beads in the treatment of hepatic malignancies: results of a multi-institutional registry.
    Cardiovascular and interventional radiology, 2010, Volume: 33, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Camptothecin; Chemoembolization, Therapeutic; Cholangiocarcinoma; Colorectal Neoplasms; Confidence Intervals; Digestive System Diseases; Dose-Response Relationship, Drug; Doxorubicin; Drug Carriers; Female; Follow-Up Studies; Hematologic Diseases; Humans; Hypertension; Irinotecan; Length of Stay; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Prospective Studies; Registries; Risk Assessment; Statistics, Nonparametric; Survival Analysis; Treatment Outcome

2010
Hepatic arterial infusion with oxaliplatin, irinotecan and doxifluridine for unresectable liver metastases of colorectal cancer.
    Anticancer research, 2010, Volume: 30, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Female; Floxuridine; Hepatic Artery; Humans; Infusions, Intra-Arterial; Iodized Oil; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin

2010
[Influence of pre-surgical chemotherapy on liver parenchyma and post-surgical outcome of patients subjected to hepatectomy due to colorectal carcinoma metastases].
    Cirugia espanola, 2010, Volume: 88, Issue:6

    Topics: Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Fatty Liver; Female; Hepatectomy; Hepatic Veno-Occlusive Disease; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Prospective Studies; Treatment Outcome

2010
Unresectable peritoneal carcinomatosis from colorectal cancer: a single center experience.
    Journal of surgical oncology, 2011, Sep-01, Volume: 104, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Carcinoma; Colorectal Neoplasms; Female; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Peritoneal Neoplasms; Retrospective Studies; Survival Rate; Treatment Outcome

2011
[Comparison between the effects of irinotecan or oxaliplatin combined with capecitabine in the treatment of advanced gastric cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011, Volume: 33, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Deoxycytidine; Diarrhea; Disease-Free Survival; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Neuritis; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Remission Induction; Stomach Neoplasms; Young Adult

2011
Bevacizumab combined with chemotherapy in the second-line treatment of metastatic colorectal cancer: results from the phase II BEVACOLOR study.
    Clinical colorectal cancer, 2012, Volume: 11, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Salvage Therapy; Survival Rate; Treatment Outcome

2012
[Chemotherapy in patients with non-resectable colorectal cancer metastases to the liver: systemic or regional?].
    Voprosy onkologii, 2011, Volume: 57, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Kaplan-Meier Estimate; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Recurrence; Splenic Neoplasms; Treatment Outcome

2011
Phase II study of irinotecan and cetuximab given every 2 weeks as second-line therapy for advanced colorectal cancer.
    Clinical colorectal cancer, 2012, Volume: 11, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Female; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Salvage Therapy; Survival Rate; Treatment Outcome

2012
The initial change in tumor size predicts response and survival in patients with metastatic colorectal cancer treated with combination chemotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Irinotecan; Kaplan-Meier Estimate; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Proportional Hazards Models; Treatment Outcome; Tumor Burden

2012
A phase I study of continuous hepatic arterial infusion of Irinotecan in patients with locally advanced hepatocellular carcinoma.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2011, Volume: 43, Issue:12

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Catheterization; Diarrhea; Disease-Free Survival; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Treatment Outcome

2011
Comparison of adjuvant systemic chemotherapy with or without hepatic arterial infusional chemotherapy after hepatic resection for metastatic colorectal cancer.
    Annals of surgery, 2011, Volume: 254, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Combined Modality Therapy; Dexamethasone; Disease-Free Survival; Female; Floxuridine; Follow-Up Studies; Hepatectomy; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin

2011
Phase II study of bi-weekly irinotecan for patients with previously treated HER2-negative metastatic breast cancer: KMBOG0610B.
    Breast cancer (Tokyo, Japan), 2013, Volume: 20, Issue:2

    Topics: Adult; Aged; Bone Neoplasms; Breast Neoplasms; Camptothecin; Drug Resistance, Neoplasm; Feasibility Studies; Female; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Prognosis; Receptor, ErbB-2; Salvage Therapy; Topoisomerase Inhibitors; Young Adult

2013
Trans-arterial chemoembolization of metastatic colorectal carcinoma to the liver adopting DC Bead®, drug-eluting bead loaded with irinotecan: results of a phase II clinical study.
    Anticancer research, 2011, Volume: 31, Issue:12

    Topics: Aged; Aged, 80 and over; Arteries; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Palliative Care; Prospective Studies; Quality of Life; Tomography, X-Ray Computed; Treatment Outcome

2011
Effectiveness of liver metastasectomies in patients with metastatic colorectal cancer treated with FIr-B/FOx triplet chemotherapy plus bevacizumab.
    Clinical colorectal cancer, 2012, Volume: 11, Issue:2

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Combined Modality Therapy; Disease-Free Survival; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Metastasectomy; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Treatment Outcome

2012
Treatment of unresectable cholangiocarcinoma: conventional transarterial chemoembolization compared with drug eluting bead-transarterial chemoembolization and systemic chemotherapy.
    European journal of gastroenterology & hepatology, 2012, Volume: 24, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Camptothecin; Chemoembolization, Therapeutic; Cholangiocarcinoma; Deoxycytidine; Epidemiologic Methods; Female; Gelatin Sponge, Absorbable; Gemcitabine; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Male; Microspheres; Middle Aged; Mitomycin; Organoplatinum Compounds; Oxaliplatin; Treatment Outcome

2012
Cetuximab rechallenge in metastatic colorectal cancer patients: how to come away from acquired resistance?
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Disease-Free Survival; Drug Resistance, Neoplasm; Exanthema; Female; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Treatment Outcome

2012
Intra-arterial infusion of irinotecan-loaded drug-eluting beads (DEBIRI) versus intravenous therapy (FOLFIRI) for hepatic metastases from colorectal cancer: final results of a phase III study.
    Anticancer research, 2012, Volume: 32, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Female; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Prospective Studies

2012
Irinotecan drug-eluting beads in the treatment of chemo-naive unresectable colorectal liver metastasis with concomitant systemic fluorouracil and oxaliplatin: results of pharmacokinetics and phase I trial.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2012, Volume: 16, Issue:8

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Drug Delivery Systems; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Prospective Studies; Survival Analysis; Treatment Outcome

2012
Yttrium-90 microsphere-selective internal radiation therapy with chemotherapy (chemo-SIRT) for colorectal cancer liver metastases: an in vivo double-arm-controlled phase II trial.
    American journal of clinical oncology, 2013, Volume: 36, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Camptothecin; Chemoradiotherapy; Colorectal Neoplasms; Female; Fluorodeoxyglucose F18; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Microspheres; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Positron-Emission Tomography; Prognosis; Prospective Studies; Radiopharmaceuticals; Tomography, X-Ray Computed; Yttrium Radioisotopes

2013
Transarterial chemoembolization with drug-eluting beads preloaded with irinotecan as a first-line approach in uveal melanoma liver metastases: tumor response and predictive value of diffusion-weighted MR imaging in five patients.
    Journal of vascular and interventional radiology : JVIR, 2012, Volume: 23, Issue:7

    Topics: Aged; Antineoplastic Agents; Camptothecin; Chemoembolization, Therapeutic; Chemotherapy, Adjuvant; Delayed-Action Preparations; Diffusion Magnetic Resonance Imaging; Female; Humans; Irinotecan; Liver Neoplasms; Magnetic Resonance Angiography; Male; Melanoma; Microspheres; Middle Aged; Prognosis; Treatment Outcome; Uveal Neoplasms

2012
Efficacy of irinotecan single drug treatment in children with refractory or recurrent hepatoblastoma--a phase II trial of the childhood liver tumour strategy group (SIOPEL).
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:18

    Topics: Adolescent; alpha-Fetoproteins; Antineoplastic Agents, Alkylating; Biomarkers, Tumor; Camptothecin; Child; Child, Preschool; Combined Modality Therapy; Diarrhea; Female; Hepatectomy; Hepatoblastoma; Humans; Infant; Irinotecan; Liver Neoplasms; Liver Transplantation; Lung Neoplasms; Male; Neoplasm Recurrence, Local; Neutropenia; Prospective Studies; Salvage Therapy; Treatment Outcome

2012
Treatment with bevacizumab and FOLFOXIRI in patients with advanced colorectal cancer: presentation of two novel trials (CHARTA and PERIMAX) and review of the literature.
    BMC cancer, 2012, Aug-16, Volume: 12

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Disease-Free Survival; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Multicenter Studies as Topic; Organoplatinum Compounds; Randomized Controlled Trials as Topic

2012
Phase I/II study of radiologic hepatic arterial infusion of fluorouracil plus systemic irinotecan for unresectable hepatic metastases from colorectal cancer: Japan Clinical Oncology Group Trial 0208-DI.
    Journal of vascular and interventional radiology : JVIR, 2012, Volume: 23, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Feasibility Studies; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Japan; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Radiography, Interventional; Time Factors; Treatment Outcome

2012
Hepatic arterial infusion with irinotecan, oxaliplatin, and floxuridine plus systemic chemotherapy as first-line treatment of unresectable liver metastases from colorectal cancer.
    Onkologie, 2012, Volume: 35, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Floxuridine; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Survival Rate; Treatment Outcome

2012
Segmental and lobar administration of drug-eluting beads delivering irinotecan leads to tumour destruction: a case-control series.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2013, Volume: 15, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Carriers; Europe; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Time Factors; Treatment Outcome

2013
Systemic irinotecan or regional floxuridine chemotherapy prolongs survival after hepatic cryosurgery in patients with metastatic colon cancer refractory to 5-fluorouracil.
    Clinical colorectal cancer, 2001, Volume: 1, Issue:1

    Topics: Antimetabolites, Antineoplastic; Camptothecin; Chemotherapy, Adjuvant; Chemotherapy, Cancer, Regional Perfusion; Colorectal Neoplasms; Cryosurgery; Disease-Free Survival; Floxuridine; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Neoplasm Recurrence, Local; Prodrugs; Survival Analysis; Tomography, X-Ray Computed; Topoisomerase I Inhibitors; Treatment Outcome

2001
Phase III comparison of two irinotecan dosing regimens in second-line therapy of metastatic colorectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Mar-01, Volume: 21, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Phytogenic; Bilirubin; Biomarkers, Tumor; Camptothecin; Colorectal Neoplasms; Disease Progression; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Prospective Studies; Quality of Life; Salvage Therapy; Survival Rate; Topoisomerase I Inhibitors; Treatment Outcome

2003
[Cytoreductive surgery of liver metastasis from colorectal cancer: principles of intra-arterial regional chemotherapy].
    Khirurgiia, 2003, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Chemotherapy, Cancer, Regional Perfusion; Colorectal Neoplasms; Female; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Male; Middle Aged; Treatment Outcome

2003
Bimonthly leucovorin, infusion 5-fluorouracil, hydroxyurea, and irinotecan (FOLFIRI-2) for pretreated metastatic colorectal cancer.
    American journal of clinical oncology, 2003, Volume: 26, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Hydroxyurea; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Survival Analysis

2003
Phase I/II study of hepatic arterial therapy with floxuridine and dexamethasone in combination with intravenous irinotecan as adjuvant treatment after resection of hepatic metastases from colorectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dexamethasone; Disease-Free Survival; Female; Floxuridine; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Male; Middle Aged; Statistics, Nonparametric; Survival Rate; Treatment Outcome

2003
Multimodal therapy with intravenous biweekly leucovorin, 5-fluorouracil and irinotecan combined with hepatic arterial infusion pirarubicin in non-resectable hepatic metastases from colorectal cancer (a European Association for Research in Oncology trial).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neutropenia

2003
Irinotecan (CPT-11) in metastatic colorectal cancer patients resistant to 5-fluorouracil (5-FU): a phase II study.
    Methods and findings in experimental and clinical pharmacology, 2003, Volume: 25, Issue:8

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Alopecia; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Diarrhea; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neutropenia; Spain; Treatment Outcome; Vomiting

2003
Continuous infusion of hepatic arterial irinotecan in pretreated patients with colorectal cancer metastatic to the liver.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2004, Volume: 15, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Topoisomerase I Inhibitors; Treatment Outcome

2004
Pilot study of low-dose, divided maximum tolerated dose of CPT-11 in 21 consecutive patients with metastatic colorectal or gastric cancer.
    Surgery today, 2004, Volume: 34, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Disease Progression; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Pilot Projects; Stomach Neoplasms

2004
Prospective multicenter phase II study of irinotecan as third-line therapy in metastatic colorectal cancer and progression after bolus and infusional 5-fluorouracil.
    Anti-cancer drugs, 2004, Volume: 15, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Prospective Studies; Treatment Outcome

2004
Oxaliplatin plus irinotecan and FU-FOL combination and pharmacokinetic analysis in advanced colorectal cancer patients.
    American journal of clinical oncology, 2004, Volume: 27, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Interactions; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Survival Analysis

2004
Phase II study of neoadjuvant 5-FU + leucovorin + CPT-11 in patients with resectable liver metastases from colorectal adenocarcinoma.
    BMC cancer, 2004, Jul-10, Volume: 4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cause of Death; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Neoplasm, Residual; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Quality of Life

2004
Irinotecan plus folinic acid/continuous 5-fluorouracil as simplified bimonthly FOLFIRI regimen for first-line therapy of metastatic colorectal cancer.
    BMC cancer, 2004, Jul-20, Volume: 4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Diarrhea; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Hematologic Diseases; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Nausea; Quality of Life; Remission Induction; Treatment Outcome

2004
Elderly patients with fluoropyrimidine and thymidylate synthase inhibitor-resistant advanced colorectal cancer derive similar benefit without excessive toxicity when treated with irinotecan monotherapy.
    British journal of cancer, 2004, Oct-18, Volume: 91, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Peritoneal Neoplasms; Prospective Studies; Quinazolines; Salvage Therapy; Survival Rate; Thiophenes; Thymidylate Synthase; Treatment Outcome

2004
Phase I dose-escalation trial of irinotecan with continuous infusion 5-FU first line, in metastatic colorectal cancer.
    British journal of cancer, 2004, Oct-18, Volume: 91, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Prognosis; Survival Rate; Treatment Outcome

2004
Sequential treatment with irinotecan and doxifluridine: optimal dosing schedule in murine models and in a phase I study for metastatic colorectal cancer.
    Chemotherapy, 2005, Volume: 51, Issue:1

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Floxuridine; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Transplantation, Heterologous

2005
Oxaliplatin combined with irinotecan and 5-fluorouracil/leucovorin (OCFL) in metastatic colorectal cancer: a phase I-II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2005, Volume: 16, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Prognosis; Survival Analysis; Treatment Outcome

2005
Phase II study of irinotecan, 5-fluorouracil and leucovorin as first-line therapy for advanced colorectal cancer.
    Japanese journal of clinical oncology, 2005, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Leukopenia; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Middle Aged; Rectal Neoplasms; Survival Analysis; Treatment Outcome

2005
Irinotecan combined with docetaxel in pre-treated metastatic breast cancer patients: a phase II study.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:5

    Topics: Adult; Aged; Anemia; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Camptothecin; Disease Progression; Disease-Free Survival; Docetaxel; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Middle Aged; Neutropenia; Taxoids

2005
Phase I study of etoposide, cisplatin and irinotecan triplet in patients with advanced-stage small-cell lung cancer.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Camptothecin; Carcinoma, Small Cell; Cisplatin; Etoposide; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Survival Analysis

2005
Phase I trial of systemic oxaliplatin combination chemotherapy with hepatic arterial infusion in patients with unresectable liver metastases from colorectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Aug-01, Volume: 23, Issue:22

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Survival Analysis; Treatment Outcome

2005
Liver resection after irinotecan, 5-fluorouracil, and folinic acid for patients with unresectable colorectal liver metastases: a multicenter phase II study by the Cancer Therapeutic Research Group.
    Medical oncology (Northwood, London, England), 2005, Volume: 22, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Disease Progression; Female; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neutropenia; Survival Analysis

2005
Phase I/II combined chemoimmunotherapy with carcinoembryonic antigen-derived HLA-A2-restricted CAP-1 peptide and irinotecan, 5-fluorouracil, and leucovorin in patients with primary metastatic colorectal cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Aug-15, Volume: 11, Issue:16

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoembryonic Antigen; CD3 Complex; CD4 Antigens; CD8 Antigens; Colorectal Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Flow Cytometry; Fluorouracil; Granulocyte-Macrophage Colony-Stimulating Factor; HLA-A2 Antigen; Humans; Immunodominant Epitopes; Immunotherapy; Interferon-gamma; Interleukin-2; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Oligopeptides; Prospective Studies; T-Lymphocytes; Treatment Outcome

2005
[Clinical evaluation of chemotherapy with irinotecan (CPT-11), l-leucovorin (l-LV), 5-fluorouracil (5-FU), and UFT for metastatic or recurrent colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Nausea; Rectal Neoplasms; Survival Rate; Tegafur; Uracil; Vomiting, Anticipatory

2005
A multicenter phase II study of "adjuvant" irinotecan following resection of colorectal hepatic metastases.
    American journal of clinical oncology, 2005, Volume: 28, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Combined Modality Therapy; Cyclin-Dependent Kinase Inhibitor p27; Disease-Free Survival; DNA, Neoplasm; Female; Fluorouracil; Gastrointestinal Diseases; Hepatectomy; Humans; Irinotecan; Life Tables; Liver Neoplasms; Male; Microsatellite Repeats; Middle Aged; Neoplasm Proteins; Neutropenia; Survival Analysis; Treatment Outcome; Tumor Suppressor Protein p53

2005
Irinotecan (CPT-11) and mitomycin-C (MMC) as second-line therapy in advanced gastric cancer: a phase II study of the Gruppo Oncologico dell' Italia Meridionale (prot. 2106).
    American journal of clinical oncology, 2005, Volume: 28, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Disease-Free Survival; Drug Synergism; Female; Granulocyte Colony-Stimulating Factor; Humans; Irinotecan; Italy; Life Tables; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Neutropenia; Peritoneal Neoplasms; Salvage Therapy; Stomach Neoplasms; Survival Analysis; Treatment Outcome

2005
Treatment with 5-fluorouracil/folinic acid, oxaliplatin, and irinotecan enables surgical resection of metastases in patients with initially unresectable metastatic colorectal cancer.
    Annals of surgical oncology, 2006, Volume: 13, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Disease Progression; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Prognosis; Survival Analysis; Treatment Outcome

2006
Irinotecan as first-line chemotherapy in patients with advanced hepatocellular carcinoma: a multicenter phase II study with dose adjustment according to baseline serum bilirubin level.
    European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Bilirubin; Biomarkers; Camptothecin; Carcinoma, Hepatocellular; Disease Progression; Dose-Response Relationship, Drug; Female; Humans; Irinotecan; Liver Cirrhosis; Liver Neoplasms; Male

2006
Increased tolerability of bimonthly 12-hour timed flat infusion 5-fluorouracil/irinotecan regimen in advanced colorectal cancer: A dose-finding study.
    Oncology reports, 2006, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Middle Aged; Time Factors

2006
Phase II study of docetaxel and irinotecan combination chemotherapy in metastatic gastric carcinoma.
    British journal of cancer, 2006, May-22, Volume: 94, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Docetaxel; Dose-Response Relationship, Drug; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Ovarian Neoplasms; Peritoneal Neoplasms; Stomach Neoplasms; Survival Rate; Taxoids

2006
Phase II study of capecitabine and irinotecan combination chemotherapy in patients with advanced gastric cancer.
    British journal of cancer, 2006, May-22, Volume: 94, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Deoxycytidine; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Ovarian Neoplasms; Peritoneal Neoplasms; Stomach Neoplasms; Survival Rate

2006
A phase II trial of S-1 monotherapy in metastatic colorectal cancer after failure of irinotecan- and oxaliplatin-containing regimens.
    British journal of cancer, 2006, Dec-18, Volume: 95, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Combinations; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Salvage Therapy; Survival Rate; Tegafur; Treatment Outcome

2006
[Combination chemotherapy with hepatic arterial infusion of 5-fluorouracil (5-FU) and systemic irinotecan (CPT-11) in patients with unresectable liver metastases from colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:13

    Topics: Adult; Aged; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neutropenia; Survival Rate

2006
Capecitabine plus oxaliplatin and irinotecan regimen every other week: a phase I/II study in first-line treatment of metastatic colorectal cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Camptothecin; Capecitabine; Colorectal Neoplasms; Confidence Intervals; Deoxycytidine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Humans; Immunohistochemistry; Irinotecan; Liver Neoplasms; Male; Maximum Tolerated Dose; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Risk Assessment; Survival Analysis; Treatment Outcome

2007
Final analysis of colorectal cancer patients treated with irinotecan and 5-fluorouracil plus folinic acid neoadjuvant chemotherapy for unresectable liver metastases.
    British journal of cancer, 2007, Oct-22, Volume: 97, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Survival Analysis; Treatment Outcome

2007
Tritherapy with fluorouracil/leucovorin, irinotecan and oxaliplatin (FOLFIRINOX): a phase II study in colorectal cancer patients with non-resectable liver metastases.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin

2008
Colorectal cancer metastasis resectability after treatment with the combination of oxaliplatin, irinotecan and 5-fluorouracil. Final results of a phase II study.
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease Progression; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Time Factors; Treatment Outcome

2008
Effect of preoperative chemotherapy on liver resection for colorectal liver metastases.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2008, Volume: 34, Issue:7

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Survival Analysis

2008
U.S. Food and Drug Administration approval: panitumumab for epidermal growth factor receptor-expressing metastatic colorectal carcinoma with progression following fluoropyrimidine-, oxaliplatin-, and irinotecan-containing chemotherapy regimens.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Mar-01, Volume: 14, Issue:5

    Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease Progression; Disease-Free Survival; Drug Approval; ErbB Receptors; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Panitumumab; Survival Rate; United States; United States Food and Drug Administration

2008
[Effect of chemotherapy using irinotecan (CPT-11) against recurrent colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Colonic Neoplasms; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Rectal Neoplasms

1995
[Late phase II study of irinotecan hydrochloride (CPT-11) in advanced gastric cancer. CPT-11 Gastrointestinal Cancer Study Group].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Irinotecan; Leukopenia; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Stomach Neoplasms

1994
[A late phase II study of CPT-11, irinotecan hydrochloride, in patients with advanced pancreatic cancer. CPT-11 Study Group on Gastrointestinal Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:7

    Topics: Adult; Aged; Alopecia; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Irinotecan; Leukopenia; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms

1994
Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer. CPT-11 Gastrointestinal Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Female; Humans; Irinotecan; Leukopenia; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Nausea; Organ Specificity; Vomiting

1993
Phase II study of a combination of irinotecan and cisplatin against metastatic gastric cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Stomach Neoplasms; Survival Rate

1999
Radioimmunotherapy of small volume disease of colorectal cancer metastatic to the liver: preclinical evaluation in comparison to standard chemotherapy and initial results of a phase I clinical study.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:10 Suppl

    Topics: Adult; Aged; Animals; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Mice; Mice, Nude; Middle Aged; Radioimmunotherapy

1999
Colorectal cancer: dilemmas regarding patient selection and toxicity prediction.
    Journal of chemotherapy (Florence, Italy), 2000, Volume: 12, Issue:3

    Topics: Adult; Antineoplastic Agents, Phytogenic; Blood Proteins; Camptothecin; Colorectal Neoplasms; Creatinine; Diarrhea; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neutropenia; Patient Selection; Risk Factors; Urea

2000
Phase II study of second-line oxaliplatin, irinotecan and mitomycin C in patients with advanced or metastatic colorectal cancer.
    Anti-cancer drugs, 2000, Volume: 11, Issue:8

    Topics: Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Mitomycin; Organoplatinum Compounds; Oxaliplatin; Treatment Outcome

2000
A phase II study of irinotecan in patients with advanced hepatocellular carcinoma.
    Cancer, 2001, Jan-01, Volume: 91, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Diarrhea; Fatigue; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Nausea; Neutropenia; Prognosis; Treatment Outcome; Vomiting

2001
Phase I study of hepatic arterial infusion of floxuridine and dexamethasone with systemic irinotecan for unresectable hepatic metastases from colorectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, May-15, Volume: 19, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Camptothecin; Carcinoma; Colonic Neoplasms; Cryosurgery; Dexamethasone; Female; Floxuridine; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Tomography, X-Ray Computed

2001
Continuous administration of irinotecan by hepatic arterial infusion: a phase I and pharmacokinetic study.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Female; Glucuronates; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Time Factors

2002
Raltitrexed (Tomudex) administration in patients with relapsed metastatic colorectal cancer after weekly irinotecan/5-Fluorouracil/Leucovorin chemotherapy.
    BMC cancer, 2002, Volume: 2

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Peritoneal Neoplasms; Quinazolines; Salvage Therapy; Secondary Prevention; Thiophenes; Treatment Outcome

2002
Systemic irinotecan and regional floxuridine after hepatic cytoreduction in 185 patients with unresectable colorectal cancer metastases.
    Annals of surgical oncology, 2002, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; California; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Cryosurgery; Disease-Free Survival; Floxuridine; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Multivariate Analysis; Proportional Hazards Models; Survival Rate

2002

Other Studies

476 other study(ies) available for irinotecan and Cancer of Liver

ArticleYear
Novel indolo-sophoridinic scaffold as Topo I inhibitors: Design, synthesis and biological evaluation as anticancer agents.
    European journal of medicinal chemistry, 2018, Aug-05, Volume: 156

    Topics: Animals; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Proliferation; Drug Design; Female; Hep G2 Cells; Humans; Indoles; Liver Neoplasms; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Structure-Activity Relationship; Topoisomerase I Inhibitors

2018
Improved Survival over Time After Resection of Colorectal Liver Metastases and Clinical Impact of Multigene Alteration Testing in Patients with Metastatic Colorectal Cancer.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2022, Volume: 26, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Colorectal Neoplasms; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Mutation; Oxaliplatin; Prognosis; Rectal Neoplasms; Survival Rate

2022
Combination Therapy of Hepatocellular Carcinoma by GPC3-Targeted Bispecific Antibody and Irinotecan is Potent in Suppressing Tumor Growth in Mice.
    Molecular cancer therapeutics, 2022, Volume: 21, Issue:1

    Topics: Animals; Antibodies, Bispecific; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Humans; Immunotherapy; Irinotecan; Liver Neoplasms; Mice; Survival Analysis

2022
Sensitizing tumors to anti-PD-1 therapy by promoting NK and CD8+ T cells via pharmacological activation of FOXO3.
    Journal for immunotherapy of cancer, 2021, Volume: 9, Issue:12

    Topics: Animals; Apoptosis; B7-H1 Antigen; Breast Neoplasms; Carcinoma, Hepatocellular; CD8-Positive T-Lymphocytes; Cell Proliferation; Female; Forkhead Box Protein O3; Gene Expression Regulation, Neoplastic; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Irinotecan; Killer Cells, Natural; Liver Neoplasms; Mice; Mice, Inbred C57BL; Ovarian Neoplasms; Prognosis; Programmed Cell Death 1 Receptor; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Tumor Microenvironment

2021
Small-size (40 µm) Beads Loaded with Irinotecan in the Treatment of Patients with Colorectal Liver Metastases.
    Cardiovascular and interventional radiology, 2022, Volume: 45, Issue:6

    Topics: Chemoembolization, Therapeutic; Colorectal Neoplasms; Humans; Irinotecan; Liver Neoplasms; Male; Microspheres; Middle Aged; Survival Rate; Treatment Outcome

2022
Small Particle DEBIRI TACE as Salvage Therapy in Patients with Liver Dominant Colorectal Cancer Metastasis: Retrospective Analysis of Safety and Outcomes.
    Current oncology (Toronto, Ont.), 2022, 01-06, Volume: 29, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Humans; Irinotecan; Liver Neoplasms; Retrospective Studies; Salvage Therapy; Treatment Outcome

2022
Correlation between Immunohistochemical Markers in Hepatocellular Carcinoma Cells and
    Canadian journal of gastroenterology & hepatology, 2022, Volume: 2022

    Topics: alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Oxaliplatin

2022
Drug-Drug Interactions and Disease Status Are Associated With Irinotecan-Induced Hepatotoxicity: A Cross-Sectional Study in Shanghai.
    Journal of clinical pharmacology, 2022, Volume: 62, Issue:9

    Topics: Antineoplastic Agents; Chemical and Drug Induced Liver Injury; China; Cross-Sectional Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Drug Interactions; Humans; Irinotecan; Liver Neoplasms

2022
Treatment of unresectable intrahepatic cholangiocarcinoma using transarterial chemoembolisation with irinotecan-eluting beads: analysis of efficacy and safety.
    Cardiovascular and interventional radiology, 2022, Volume: 45, Issue:8

    Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cholangiocarcinoma; Humans; Irinotecan; Liver Neoplasms; Retrospective Studies; Topoisomerase I Inhibitors; Treatment Outcome

2022
The Efficacy and Safety of Hepatic Arterial Infusion Chemotherapy Based on FOLFIRI for Advanced Intrahepatic Cholangiocarcinoma as Second-Line and Successive Treatment: A Real-World Study.
    Canadian journal of gastroenterology & hepatology, 2022, Volume: 2022

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cholangiocarcinoma; Cisplatin; Fluorouracil; Humans; Immune Checkpoint Inhibitors; Irinotecan; Leucovorin; Liver Neoplasms; Treatment Outcome

2022
Clinical application of irinotecan combined with first-line chemotherapeutics against pediatric hepatoblastoma with pulmonary metastasis.
    Pakistan journal of pharmaceutical sciences, 2022, Volume: 35, Issue:5

    Topics: alpha-Fetoproteins; Child; Cisplatin; Hepatoblastoma; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Vincristine

2022
Survival of Patients with Colorectal Liver Metastases after Transarterial Chemoembolization Using Irinotecan-Eluting Microspheres: A Single-Center Retrospective Analysis Comparing RECIST 1.1 and Choi Criteria.
    Journal of vascular and interventional radiology : JVIR, 2023, Volume: 34, Issue:6

    Topics: Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Colorectal Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms; Male; Microspheres; Middle Aged; Response Evaluation Criteria in Solid Tumors; Retrospective Studies; Treatment Outcome

2023
Drug-eluting beads loaded with irinotecan to treat synchronous liver-only metastases of colorectal cancer non-responsive to bevacizumab-based chemotherapy.
    The British journal of radiology, 2023, Apr-01, Volume: 96, Issue:1145

    Topics: Antineoplastic Agents, Phytogenic; Bevacizumab; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Humans; Irinotecan; Liver Neoplasms; Treatment Outcome

2023
A "Trojan Horse" Strategy: The Preparation of Bile Acid-Modifying Irinotecan Hydrochloride Nanoliposomes for Liver-Targeted Anticancer Drug Delivery System Study.
    Molecules (Basel, Switzerland), 2023, Feb-07, Volume: 28, Issue:4

    Topics: Animals; Antineoplastic Agents; Bile Acids and Salts; Carcinoma, Hepatocellular; Cholic Acids; Drug Delivery Systems; Irinotecan; Liposomes; Liver Neoplasms; Mice

2023
CT-based radiomics for the identification of colorectal cancer liver metastases sensitive to first-line irinotecan-based chemotherapy.
    Medical physics, 2023, Volume: 50, Issue:5

    Topics: Colorectal Neoplasms; Humans; Irinotecan; Liver Neoplasms; Retrospective Studies; Tomography, X-Ray Computed

2023
Vincristine/irinotecan/temsirolimus upfront window treatment of high-risk hepatoblastoma: A report from the Children's Oncology Group AHEP0731 Study Committee.
    Pediatric blood & cancer, 2023, Volume: 70, Issue:7

    Topics: alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Child; Hepatoblastoma; Humans; Irinotecan; Liver Neoplasms; Treatment Outcome; Vincristine

2023
Hepatic arterial infusion with nanoliposomal irinotecan leads to significant regression of tumor size of colorectal liver metastases in a CC531 rat model.
    Clinical & experimental metastasis, 2023, Volume: 40, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Colonic Neoplasms; Colorectal Neoplasms; Fluorouracil; Hepatic Artery; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Rats

2023
Prospective Series of Transarterial Chemoembolization of Metastatic Colorectal Cancer to the Liver with 30-60 μm Microspheres Loaded with Irinotecan.
    Cardiovascular and interventional radiology, 2023, Volume: 46, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Colonic Neoplasms; Colorectal Neoplasms; Humans; Irinotecan; Liver Neoplasms; Microspheres; Middle Aged; Prospective Studies; Rectal Neoplasms

2023
Risk factors for irinotecan-induced liver injury: a retrospective multicentre cross-sectional study in China.
    BMJ open, 2023, 06-22, Volume: 13, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemical and Drug Induced Liver Injury, Chronic; Cross-Sectional Studies; Humans; Irinotecan; Liver Neoplasms; Retrospective Studies; Risk Factors

2023
Prognostic Value of TACE With Irinotecan-loaded Drug-eluting Beads (DEBIRI) in Patients With Liver Metastases from Unresectable Colorectal Cancer.
    Anticancer research, 2023, Volume: 43, Issue:8

    Topics: Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Colorectal Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms; Male; Prognosis; Topoisomerase I Inhibitors; Treatment Outcome

2023
Feasibility and Safety of CT-Guided High-Dose-Rate Brachytherapy Combined with Transarterial Chemoembolization Using Irinotecan-Loaded Microspheres for the Treatment of Large, Unresectable Colorectal Liver Metastases.
    Journal of vascular and interventional radiology : JVIR, 2020, Volume: 31, Issue:2

    Topics: Aged; Aged, 80 and over; Brachytherapy; Chemoembolization, Therapeutic; Chemoradiotherapy; Colorectal Neoplasms; Feasibility Studies; Female; Humans; Irinotecan; Liver Neoplasms; Male; Microspheres; Middle Aged; Predictive Value of Tests; Progression-Free Survival; Prospective Studies; Radiation Dosage; Time Factors; Tomography, X-Ray Computed; Topoisomerase I Inhibitors; Tumor Burden

2020
Dramatic response of FOLFIRINOX regimen in a collision pancreatic adenocarcinoma patient with a germline BRCA2 mutation: a case report.
    Japanese journal of clinical oncology, 2019, Dec-18, Volume: 49, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; BRCA2 Protein; Carcinoma, Ductal, Breast; Carcinoma, Pancreatic Ductal; Female; Fluorouracil; Genetic Testing; Germ Cells; Germ-Line Mutation; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymph Node Excision; Middle Aged; Mutation; Oxaliplatin; Pancreatic Neoplasms; Pancreaticoduodenectomy

2019
The Significance of Sidedness in Patients with Metastatic Colorectal Cancer Treated with Triplet First-line Chemotherapy.
    Asian Pacific journal of cancer prevention : APJCP, 2019, Oct-01, Volume: 20, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Colorectal Neoplasms; Female; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Oxaliplatin; Prognosis; Prospective Studies; Retrospective Studies; Survival Rate; Young Adult

2019
Modeling Tumor Evolutionary Dynamics to Predict Clinical Outcomes for Patients with Metastatic Colorectal Cancer: A Retrospective Analysis.
    Cancer research, 2020, 02-01, Volume: 80, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biological Evolution; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Disease Progression; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Longitudinal Studies; Male; Middle Aged; Models, Theoretical; Multicenter Studies as Topic; Panitumumab; Prognosis; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Rate

2020
Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or PALB2 mutation.
    British journal of cancer, 2020, Volume: 122, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Albumins; Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; BRCA2 Protein; Carcinoma, Pancreatic Ductal; Case-Control Studies; Cisplatin; Deoxycytidine; Fanconi Anemia Complementation Group N Protein; Female; Fluorouracil; Gemcitabine; Germ-Line Mutation; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Pancreatic Neoplasms; Prognosis; Progression-Free Survival; Retrospective Studies

2020
The Proteomic Landscape of Pancreatic Ductal Adenocarcinoma Liver Metastases Identifies Molecular Subtypes and Associations with Clinical Response.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 03-01, Volume: 26, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Molecular Typing; Oxaliplatin; Pancreatic Neoplasms; Proteome; Proteomics; Survival Rate; Treatment Outcome

2020
Radiomics Response Signature for Identification of Metastatic Colorectal Cancer Sensitive to Therapies Targeting EGFR Pathway.
    Journal of the National Cancer Institute, 2020, 09-01, Volume: 112, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Biomarkers, Tumor; Cetuximab; Cohort Studies; Colorectal Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Image Processing, Computer-Assisted; Irinotecan; Leucovorin; Liver Neoplasms; Male; Molecular Targeted Therapy; Neoplasm Metastasis; Response Evaluation Criteria in Solid Tumors; Retrospective Studies; Signal Transduction; Tomography, X-Ray Computed; Transcriptome

2020
Steatohepatitis due to FOLFIRINOX regimen in adjuvant pancreas cancer treatment mimicking liver metastasis.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2020, Volume: 26, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Fatty Liver; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Middle Aged; Oxaliplatin; Pancreatic Neoplasms

2020
Does Bead Size Affect Patient Outcome in Irinotecan-Loaded Beads Chemoembolization Plus Systemic Chemotherapy Regimens for Liver-Dominant Colorectal Cancer? Results of an Observational Study.
    Cardiovascular and interventional radiology, 2020, Volume: 43, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Chemoembolization, Therapeutic; Colorectal Neoplasms; Combined Modality Therapy; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Topoisomerase I Inhibitors; Treatment Outcome

2020
A patient-derived xenograft and a cell line derived from it form a useful preclinical model for small bowel adenocarcinoma.
    Cancer medicine, 2020, Volume: 9, Issue:10

    Topics: Adenocarcinoma; Aged; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Evaluation, Preclinical; Female; Fluorouracil; Gemcitabine; Heterografts; HT29 Cells; Humans; Inhibitory Concentration 50; Irinotecan; Jejunal Neoplasms; Leucovorin; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Peritoneal Neoplasms; Treatment Failure; Trifluridine; Xenograft Model Antitumor Assays

2020
Stepwise targeting and responsive lipid-coated nanoparticles for enhanced tumor cell sensitivity and hepatocellular carcinoma therapy.
    Theranostics, 2020, Volume: 10, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Carriers; Drug Liberation; Humans; Irinotecan; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Rats; Rats, Sprague-Dawley; Silicon Dioxide; Tumor Microenvironment

2020
Stressing the need for prolonged immediate surveillance after chemoembolization for liver metastases using drug-eluted beads with irinotecan.
    Diagnostic and interventional imaging, 2020, Volume: 101, Issue:11

    Topics: Chemoembolization, Therapeutic; Colorectal Neoplasms; Humans; Irinotecan; Liver Neoplasms; Microspheres; Pharmaceutical Preparations; Treatment Outcome

2020
Clinical utility of polyethylene glycol conjugated granulocyte colony-stimulating factor (PEG-G-CSF) for preventing severe neutropenia in metastatic colorectal cancer patients treated with FOLFOXIRI plus bevacizumab: a single-center retrospective study.
    BMC cancer, 2020, Apr-28, Volume: 20, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neutropenia; Oxaliplatin; Peritoneal Neoplasms; Polyethylene Glycols; Prognosis; Retrospective Studies; Survival Rate

2020
Prognostic impact of immune-microenvironment in colorectal liver metastases resected after triplets plus a biologic agent: A pooled analysis of five prospective trials.
    European journal of cancer (Oxford, England : 1990), 2020, Volume: 135

    Topics: Aged; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colorectal Neoplasms; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphocytes, Tumor-Infiltrating; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies; Time Factors; Treatment Outcome; Tumor Microenvironment

2020
A multicentre, international, observational study on transarterial chemoembolisation in colorectal cancer liver metastases: Design and rationale of CIREL.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2020, Volume: 52, Issue:8

    Topics: Chemoembolization, Therapeutic; Colorectal Neoplasms; Humans; Irinotecan; Liver Neoplasms; Microspheres; Prospective Studies; Research Design

2020
Exceptional Response to A Single Cycle of Immunotherapy in a Lynch Syndrome Patient with Metastatic Pancreatic Adenocarcinoma.
    The American journal of case reports, 2020, Jul-13, Volume: 21

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms, Hereditary Nonpolyposis; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Oxaliplatin; Pancreatic Neoplasms

2020
Prognosis and personalized treatment prediction in TP53-mutant hepatocellular carcinoma: an in silico strategy towards precision oncology.
    Briefings in bioinformatics, 2021, 05-20, Volume: 22, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Computer Simulation; Disease-Free Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Irinotecan; Liver Neoplasms; Male; Mutation; Naphthoquinones; Precision Medicine; Survival Rate; Tumor Suppressor Protein p53

2021
Safety and Tolerability of Topotecan-Eluting Radiopaque Microspheres for Hepatic Chemoembolization in a Rabbit Preclinical Model.
    Cardiovascular and interventional radiology, 2020, Volume: 43, Issue:12

    Topics: Animals; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Humans; Irinotecan; Liver Neoplasms; Liver Neoplasms, Experimental; Microspheres; Rabbits; Topoisomerase I Inhibitors; Topotecan

2020
The introduction of immunosuppressor (TDO inhibitor) significantly improved the efficacy of irinotecan in treating hepatocellular carcinoma.
    Cancer immunology, immunotherapy : CII, 2021, Volume: 70, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Humans; Immunotherapy; Irinotecan; Liver Neoplasms; Mice; Topoisomerase I Inhibitors

2021
Comparison of FOLFIRINOX and Gemcitabine Plus Nab-paclitaxel for Treatment of Metastatic Pancreatic Cancer: Using Korean Pancreatic Cancer (K-PaC) Registry.
    American journal of clinical oncology, 2020, Volume: 43, Issue:9

    Topics: Aged; Albumins; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Cross-Over Studies; Deoxycytidine; Febrile Neutropenia; Female; Fluorouracil; Gemcitabine; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Oxaliplatin; Paclitaxel; Pancreatic Neoplasms; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Progression-Free Survival; Registries; Republic of Korea; Survival Rate; Treatment Outcome

2020
LifePearl microspheres loaded with irinotecan in the treatment of Liver-dominant metastatic colorectal carcinoma: feasibility, safety and pharmacokinetic study.
    Anti-cancer drugs, 2020, Volume: 31, Issue:10

    Topics: Aged; Antineoplastic Agents; Colorectal Neoplasms; Drug Delivery Systems; Embolization, Therapeutic; Feasibility Studies; Female; Humans; Irinotecan; Liver Neoplasms; Male; Microspheres; Middle Aged

2020
The CIREL Cohort: A Prospective Controlled Registry Studying the Real-Life Use of Irinotecan-Loaded Chemoembolisation in Colorectal Cancer Liver Metastases: Interim Analysis.
    Cardiovascular and interventional radiology, 2021, Volume: 44, Issue:1

    Topics: Aged; Chemoembolization, Therapeutic; Colorectal Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms; Male; Microspheres; Neoplasm Metastasis; Prospective Studies; Quality of Life; Registries; Topoisomerase I Inhibitors

2021
Extrahepatic recurrence rates in patients receiving adjuvant hepatic artery infusion and systemic chemotherapy after complete resection of colorectal liver metastases.
    Journal of surgical oncology, 2020, Volume: 122, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Hepatic Artery; Humans; Incidence; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Oxaliplatin; Prognosis; Prospective Studies; Survival Rate; United States

2020
Salinomycin-Loaded Small-Molecule Nanoprodrugs Enhance Anticancer Activity in Hepatocellular Carcinoma.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Irinotecan; Linoleic Acid; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplastic Stem Cells; Phosphatidylethanolamines; Polyethylene Glycols; Prodrugs; Pyrans; Xenograft Model Antitumor Assays

2020
Bridge to surgery after irinotecan-based liver chemoembolization for metastatic gastric adenocarcinoma: Letter to the editor.
    Clinics and research in hepatology and gastroenterology, 2021, Volume: 45, Issue:5

    Topics: Adenocarcinoma; Chemoembolization, Therapeutic; Humans; Irinotecan; Liver Neoplasms; Stomach Neoplasms

2021
Modulation of Immune Checkpoints by Chemotherapy in Human Colorectal Liver Metastases.
    Cell reports. Medicine, 2020, 12-22, Volume: 1, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Hepatitis A Virus Cellular Receptor 2; Humans; Irinotecan; Liver Neoplasms; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Programmed Cell Death 1 Receptor; Tumor Microenvironment

2020
Identification of PARP-1 in cancer stem cells of gastrointestinal cancers: A preliminary study.
    Journal of biosciences, 2021, Volume: 46

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Colonic Neoplasms; Deoxycytidine; Doxorubicin; Drug Resistance, Neoplasm; Fluorouracil; Gastrointestinal Neoplasms; Gemcitabine; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Irinotecan; Liver Neoplasms; Mice; Neoplastic Stem Cells; Pancreatic Neoplasms; Phthalazines; Piperazines; Poly (ADP-Ribose) Polymerase-1; Xenograft Model Antitumor Assays

2021
Complications Following Irinotecan-Loaded Microsphere Chemoembolization of Colorectal Metastatic Liver Lesions Associated with Hepatic-Artery Branch Temporary Stasis.
    Current oncology (Toronto, Ont.), 2021, 06-20, Volume: 28, Issue:3

    Topics: Arteries; Chemoembolization, Therapeutic; Colorectal Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms; Male; Microspheres

2021
Irinotecan eluting beads-transarterial chemoembolization using Callispheres® microspheres is an effective and safe approach in treating unresectable colorectal cancer liver metastases.
    Irish journal of medical science, 2022, Volume: 191, Issue:3

    Topics: Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Colorectal Neoplasms; Humans; Irinotecan; Liver Neoplasms; Microspheres; Treatment Outcome

2022
Overall Survival Prediction and Usefulness of Second-Line Chemotherapy in Advanced Pancreatic Adenocarcinoma.
    Journal of the National Cancer Institute, 2017, 10-01, Volume: 109, Issue:10

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Camptothecin; Cancer Pain; Carcinoma, Pancreatic Ductal; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Gemcitabine; Health Status; Humans; Irinotecan; Jaundice; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Nomograms; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Proportional Hazards Models; Prospective Studies; Retreatment; Risk Factors; Smoking; Survival Rate

2017
Resection of colorectal liver metastases after second-line chemotherapy: is it worthwhile? A LiverMetSurvey analysis of 6415 patients.
    European journal of cancer (Oxford, England : 1990), 2017, Volume: 78

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Catheter Ablation; Cetuximab; Colonic Neoplasms; Disease Progression; Disease-Free Survival; Female; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Panitumumab; Postoperative Care; Preoperative Care; Prospective Studies; Rectal Neoplasms; Registries

2017
PLGA-PEG-RA-based polymeric micelles for tumor targeted delivery of irinotecan.
    Pharmaceutical development and technology, 2018, Volume: 23, Issue:1

    Topics: Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Hep G2 Cells; HT29 Cells; Humans; Irinotecan; Lactic Acid; Liver Neoplasms; Micelles; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglactin 910; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tretinoin

2018
Modified-FOLFIRINOX in metastatic pancreatic cancer: A prospective study in Chinese population.
    Cancer letters, 2017, 10-10, Volume: 406

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; China; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Peritoneal Neoplasms; Prognosis; Prospective Studies; Survival Rate

2017
Preoperative bevacizumab and volumetric recovery after resection of colorectal liver metastases.
    Journal of surgical oncology, 2017, Volume: 116, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Female; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Liver Regeneration; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin

2017
Aggressive large-cell neuroendocrine carcinoma of the sigmoid colon in a patient with ulcerative colitis.
    BMJ case reports, 2017, Aug-07, Volume: 2017

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Carcinoma, Neuroendocrine; Colitis, Ulcerative; Fatal Outcome; Female; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Precancerous Conditions; Risk Factors; Sigmoid Neoplasms; Tomography, X-Ray Computed

2017
Prognostic Significance of Surgical Margin Size After Neoadjuvant FOLFOX and/or FOLFIRI for Colorectal Liver Metastases.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2017, Volume: 21, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Margins of Excision; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Prognosis; Treatment Outcome

2017
Characterization of Pulmonary Metastases in Children With Hepatoblastoma Treated on Children's Oncology Group Protocol AHEP0731 (The Treatment of Children With All Stages of Hepatoblastoma): A Report From the Children's Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Oct-20, Volume: 35, Issue:30

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Child; Child, Preschool; Cisplatin; Disease-Free Survival; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Hepatoblastoma; Humans; Infant; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Pneumonectomy; Prognosis; Tomography, X-Ray Computed; Treatment Outcome; Vincristine

2017
Estimation of the future remnant liver function is a better tool to predict post-hepatectomy liver failure than platelet-based liver scores.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2017, Volume: 43, Issue:12

    Topics: Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Glycine; Hepatectomy; Humans; Imino Acids; Irinotecan; Liver Failure; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Organotechnetium Compounds; Oxaliplatin; Platelet Function Tests; Predictive Value of Tests; Radiopharmaceuticals; Treatment Outcome

2017
Long-term survival in a patient with low-level inflammatory markers and liver metastasis, converted resectable by TACE.
    Immunotherapy, 2017, Volume: 9, Issue:13

    Topics: Adenocarcinoma; Adult; Biomarkers; Camptothecin; Capecitabine; Chemoembolization, Therapeutic; Colectomy; Colonic Neoplasms; Fluorouracil; Hepatectomy; Humans; Inflammation Mediators; Irinotecan; Leucovorin; Liver Neoplasms; Male; Microspheres; Organoplatinum Compounds; Oxaliplatin; Remission Induction

2017
Bronchobiliary Fistula, a Late Complication of Liver Surgery.
    Archivos de bronconeumologia, 2018, Volume: 54, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biliary Fistula; Bronchial Fistula; Cetuximab; Cholecystectomy; Combined Modality Therapy; Embolization, Therapeutic; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Postoperative Complications; Sigmoid Neoplasms; Splenectomy; Tomography, X-Ray Computed

2018
Irinotecan and Oxaliplatin Might Provide Equal Benefit as Adjuvant Chemotherapy for Patients with Resectable Synchronous Colon Cancer and Liver-confined Metastases: A Nationwide Database Study.
    Anticancer research, 2017, Volume: 37, Issue:12

    Topics: Aged; Antineoplastic Agents; Camptothecin; Chemotherapy, Adjuvant; Colonic Neoplasms; Databases, Factual; Female; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Organoplatinum Compounds; Outcome Assessment, Health Care; Oxaliplatin; Proportional Hazards Models; Retrospective Studies; Taiwan

2017
KRAS and 2 rare PI3KCA mutations coexisting in a metastatic colorectal cancer patient with aggressive and resistant disease.
    Human pathology, 2018, Volume: 74

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; DNA Mutational Analysis; ErbB Receptors; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Mutation; Nuclear Proteins; Oxaliplatin; Proto-Oncogene Proteins p21(ras); Transcription Factors; Treatment Outcome

2018
Surgical Strategy Based on Indocyanine Green Test for Chemotherapy-Associated Liver Injury and Long-Term Outcome in Colorectal Liver Metastases.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2018, Volume: 22, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Clinical Decision-Making; Colorectal Neoplasms; Coloring Agents; Disease-Free Survival; Female; Hepatectomy; Humans; Indocyanine Green; Irinotecan; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Oxaliplatin; Survival Rate; Time Factors; Tumor Burden

2018
Progression of Colorectal Liver Metastases from the End of Chemotherapy to Resection: A New Contraindication to Surgery?
    Annals of surgical oncology, 2018, Volume: 25, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Contraindications, Procedure; Disease Progression; Disease-Free Survival; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Oxaliplatin; Response Evaluation Criteria in Solid Tumors; Risk Factors; Survival Rate; Tomography, X-Ray Computed; Tumor Burden

2018
Addition of Vincristine and Irinotecan to Standard Therapy in a Patient With Refractory High-risk Hepatoblastoma Achieving Long-term Relapse-free Survival.
    Journal of pediatric hematology/oncology, 2019, Volume: 41, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cisplatin; Combined Modality Therapy; Disease-Free Survival; Doxorubicin; Female; Fluorouracil; Hepatoblastoma; Humans; Irinotecan; Liver Neoplasms; Risk; Vincristine

2019
Survival of patients with non-resectable, chemotherapy-resistant colorectal cancer liver metastases undergoing conventional lipiodol-based transarterial chemoembolization (cTACE) palliatively versus neoadjuvantly prior to percutaneous thermal ablation.
    European journal of radiology, 2018, Volume: 102

    Topics: Ablation Techniques; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoembolization, Therapeutic; Cisplatin; Colonic Neoplasms; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Ethiodized Oil; Female; Gemcitabine; Humans; Hyperthermia, Induced; Irinotecan; Laser Therapy; Liver Neoplasms; Male; Microwaves; Middle Aged; Mitomycin; Neoadjuvant Therapy; Palliative Care; Prognosis; Rectal Neoplasms; Retrospective Studies; Survival Rate; Treatment Outcome; Young Adult

2018
Pathological response of colorectal liver metastases treated after induction treatment.
    La Tunisie medicale, 2017, Volume: 95, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Cross-Sectional Studies; Disease-Free Survival; Female; Hepatectomy; Histological Techniques; Humans; Induction Chemotherapy; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Oxaliplatin; Remission Induction; Treatment Outcome; Tumor Burden; Young Adult

2017
Transarterial Embolization with Small-Size Particles Loaded with Irinotecan for the Treatment of Colorectal Liver Metastases: Results of the MIRACLE III Study.
    Cardiovascular and interventional radiology, 2018, Volume: 41, Issue:11

    Topics: Aged; Aged, 80 and over; Chemoembolization, Therapeutic; Colorectal Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms; Male; Microspheres; Middle Aged; Pilot Projects; Progression-Free Survival; Prospective Studies; Treatment Outcome

2018
Transarterial Chemoembolization (TACE) Using Mitomycin with or without Irinotecan for Hepatocellular Carcinoma in European Patients.
    Oncology research and treatment, 2018, Volume: 41, Issue:7-8

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Disease-Free Survival; Ethiodized Oil; Female; Humans; Irinotecan; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Mitomycin; Outcome Assessment, Health Care; Starch

2018
Chemoembolization in Conjunction with Bevacizumab: Preliminary Results.
    Journal of vascular and interventional radiology : JVIR, 2018, Volume: 29, Issue:9

    Topics: Administration, Intravenous; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Female; Humans; Irinotecan; Italy; Liver Neoplasms; Male; Middle Aged; Preliminary Data; Prospective Studies; Quality of Life; Tomography, X-Ray Computed; Treatment Outcome

2018
Bevacizumab-based Chemotherapy for Poorly-differentiated Neuroendocrine Tumors.
    Anticancer research, 2018, Volume: 38, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neuroendocrine Tumors; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies; Survival Rate; Treatment Outcome

2018
Prognostic Effect of Adenosine-related Genetic Variants in Metastatic Colorectal Cancer Treated With Bevacizumab-based Chemotherapy.
    Clinical colorectal cancer, 2019, Volume: 18, Issue:1

    Topics: 5'-Nucleotidase; Adenosine; Antineoplastic Combined Chemotherapy Protocols; Apyrase; Bevacizumab; Biomarkers, Tumor; Camptothecin; Cetuximab; Cohort Studies; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; GPI-Linked Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Polymorphism, Single Nucleotide; Prognosis; Receptors, Purinergic P1; Survival Rate

2019
Pilot Study Comparing Systemic and Tissue Pharmacokinetics of Irinotecan and Metabolites after Hepatic Drug-Eluting Chemoembolization.
    Journal of vascular and interventional radiology : JVIR, 2019, Volume: 30, Issue:1

    Topics: Adult; Aged; Chemoembolization, Therapeutic; Drug Monitoring; Female; Genotype; Glucuronosyltransferase; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Models, Biological; Mutation; Pharmacogenomic Testing; Pharmacogenomic Variants; Phenotype; Pilot Projects; Prospective Studies; Topoisomerase I Inhibitors; Treatment Outcome

2019
Second-line treatment efficacy and toxicity in older vs. non-older patients with advanced gastric cancer: A multicentre real-world study.
    Journal of geriatric oncology, 2019, Volume: 10, Issue:4

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma; Chemotherapy, Adjuvant; Cohort Studies; Disease Progression; Docetaxel; Female; Fluorouracil; Humans; Irinotecan; Italy; Kaplan-Meier Estimate; L-Lactate Dehydrogenase; Liver Neoplasms; Lymph Nodes; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Paclitaxel; Peritoneal Neoplasms; Platinum Compounds; Progression-Free Survival; Proportional Hazards Models; Receptor, ErbB-2; Retrospective Studies; Stomach Neoplasms; Treatment Failure

2019
The clinical conundrum of managing relapsed small cell lung cancer.
    Cancer, 2019, 04-01, Volume: 125, Issue:7

    Topics: Anthracyclines; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Benzodiazepinones; Carboplatin; Clinical Decision-Making; Disease Progression; Etoposide; Humans; Immunoconjugates; Irinotecan; Liver Neoplasms; Lung Neoplasms; Molecular Targeted Therapy; Neoplasm Recurrence, Local; Nivolumab; Paclitaxel; Piperazines; Pyrimidines; Salvage Therapy; Small Cell Lung Carcinoma; Temozolomide; Thiourea; Topotecan

2019
[A Case of Successful Treatment of Recurrent Liver Metastases from Mixed Adenoneuroendocrine Carcinoma of the Pancreas with Everolimus Administration].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:12

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Everolimus; Humans; Irinotecan; Liver Neoplasms; Male; Pancreatic Neoplasms; Positron Emission Tomography Computed Tomography

2018
Hepatic arterial infusion of irinotecan and EmboCept
    Clinical & experimental metastasis, 2019, Volume: 36, Issue:1

    Topics: Animals; Apoptosis; Cell Proliferation; Colorectal Neoplasms; Hepatic Artery; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Rats; Starch; Topoisomerase I Inhibitors; Tumor Cells, Cultured

2019
[A Case of Choriocarcinoma of the Small Intestine with Multiple Lung and Liver Metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cisplatin; Humans; Intestinal Neoplasms; Irinotecan; Liver Neoplasms; Male

2018
Response to preoperative chemotherapy: impact of change in total burden score and mutational tumor status on prognosis of patients undergoing resection for colorectal liver metastases.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2019, Volume: 21, Issue:9

    Topics: Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Mutation; Neoadjuvant Therapy; Neoplasm Staging; Oxaliplatin; Prognosis; Retrospective Studies; Tumor Burden

2019
Long-term control with chemoradiation of initially metastatic mixed adenoneuroendocrine carcinoma of the rectum: a case report.
    Journal of medical case reports, 2019, Mar-23, Volume: 13, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Neuroendocrine; Chemoradiotherapy; Cisplatin; Female; Humans; Irinotecan; Liver Neoplasms; Magnetic Resonance Imaging; Middle Aged; Neoplasm Staging; Rectal Neoplasms; Remission Induction; Tomography, X-Ray Computed; Topoisomerase I Inhibitors

2019
Conversion surgery for initially unresectable pancreatic ductal adenocarcinoma with synchronous liver metastasis after treatment with FOLFIRINOX.
    Clinical journal of gastroenterology, 2019, Volume: 12, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Oxaliplatin; Pancreatic Neoplasms; Treatment Outcome

2019
Transarterial Chemoembolisation of Colorectal Liver Metastases with Irinotecan-Loaded Beads: A Bi-institutional Analysis of 125 Treatments in 53 Patients.
    Cardiovascular and interventional radiology, 2019, Volume: 42, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Chemoembolization, Therapeutic; Colorectal Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Retrospective Studies; Survival Analysis; Topoisomerase I Inhibitors; Treatment Outcome

2019
Predicting pharmacokinetic behaviour of drug release from drug-eluting embolization beads using in vitro elution methods.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Aug-01, Volume: 136

    Topics: Animals; Chemoembolization, Therapeutic; Doxorubicin; Drug Delivery Systems; Drug Liberation; In Vitro Techniques; Irinotecan; Liver; Liver Neoplasms; Piperidines; Quinazolines; Swine

2019
Spontaneous regression of pancreatic cancer with liver metastases.
    BMJ case reports, 2019, May-31, Volume: 12, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lupus Erythematosus, Discoid; Middle Aged; Neoplasm Metastasis; Neoplasm Regression, Spontaneous; Oxaliplatin; Pancreatic Neoplasms

2019
Comparison of Response and Outcomes of Drug-eluting Bead Chemoembolization (DEB-TACE)
    Anticancer research, 2019, Volume: 39, Issue:6

    Topics: Aged; Antineoplastic Agents; Chemoembolization, Therapeutic; Colorectal Neoplasms; Disease Progression; Doxorubicin; Drug Carriers; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Progression-Free Survival; Radiopharmaceuticals; Retrospective Studies; Risk Factors; Time Factors

2019
The seemingly innocuous presentation of metastatic pancreatic tail cancer: a case report.
    Journal of medical case reports, 2019, Jun-11, Volume: 13, Issue:1

    Topics: Abdominal Pain; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Diabetes Mellitus; Diagnosis, Differential; Early Detection of Cancer; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Oxaliplatin; Pancreas; Pancreatic Neoplasms; Risk Factors

2019
Sustained Remission After Maintenance Irinotecan in Patient With Multiply Relapsed Hepatoblastoma.
    Journal of pediatric hematology/oncology, 2020, Volume: 42, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Chemotherapy, Adjuvant; Disease-Free Survival; Etoposide; Hepatoblastoma; Humans; Ifosfamide; Infant; Irinotecan; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Remission Induction

2020
Activity of the mTOR inhibitor RAD001, the dual mTOR and PI3-kinase inhibitor BEZ235 and the PI3-kinase inhibitor BKM120 in hepatocellular carcinoma.
    Liver international : official journal of the International Association for the Study of the Liver, 2013, Volume: 33, Issue:5

    Topics: Aminopyridines; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Camptothecin; Carcinoma, Hepatocellular; Cell Cycle; Cell Line; Cell Respiration; Cisplatin; Doxorubicin; Everolimus; Humans; Imidazoles; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; Irinotecan; Liver Neoplasms; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Quinolines; Sirolimus; TOR Serine-Threonine Kinases

2013
Transarterial chemoembolization using DEBIRI for treatment of hepatic metastases from colorectal cancer.
    Anticancer research, 2013, Volume: 33, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Female; Follow-Up Studies; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Microspheres; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate

2013
Transcatheter arterial chemoembolization (TACE) of colorectal cancer liver metastases by irinotecan-eluting microspheres in a salvage patient population.
    Cardiovascular and interventional radiology, 2014, Volume: 37, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Drug Carriers; Female; Humans; Irinotecan; Liver Neoplasms; Male; Microspheres; Middle Aged; Polymers; Prospective Studies; Salvage Therapy; Tomography, X-Ray Computed; Treatment Outcome

2014
XELIRI plus bevacizumab compared with FOLFIRI plus bevacizumab as first-line setting in patients with metastatic colorectal cancer: experiences at two-institutions.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:4

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate; Young Adult

2013
Adjuvant systemic chemotherapy after putative curative resection of colorectal liver and lung metastases.
    Clinical colorectal cancer, 2013, Volume: 12, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Metastasectomy; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate

2013
Investigation of the mechanisms governing doxorubicin and irinotecan release from drug-eluting beads: mathematical modeling and experimental verification.
    Journal of materials science. Materials in medicine, 2013, Volume: 24, Issue:10

    Topics: Antineoplastic Agents; Camptothecin; Diffusion; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Evaluation, Preclinical; Humans; Hydrogels; Irinotecan; Kinetics; Liver Neoplasms; Models, Theoretical; Particle Size; Time Factors; Water

2013
[A case of synchronous liver metastasis originating from advanced gastric cancer treated with combination chemotherapy involving S-1 and surgical intervention].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Combined Modality Therapy; Drug Combinations; Gastrectomy; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Oxonic Acid; Stomach Neoplasms; Tegafur; Tomography, X-Ray Computed

2013
[A case of metastatic colon cancer effectively treated by XELOX and IRIS].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Colonic Neoplasms; Deoxycytidine; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Oxaloacetates; Oxonic Acid; Tegafur; Tomography, X-Ray Computed

2013
[Preliminary study on the efficacy of irinotecan in the treatment of childhood relapsed hepatoblastoma].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2013, Volume: 15, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Child; Child, Preschool; Female; Hepatoblastoma; Humans; Irinotecan; Liver Neoplasms; Male; Neoplasm Recurrence, Local

2013
Analysis of UGT1A1*28 genotype and SN-38 pharmacokinetics for irinotecan-based chemotherapy in patients with advanced colorectal cancer: results from a multicenter, retrospective study in Shanghai.
    Journal of cancer research and clinical oncology, 2013, Volume: 139, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Camptothecin; China; Colorectal Neoplasms; Female; Follow-Up Studies; Genotype; Glucuronosyltransferase; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Polymorphism, Genetic; Prognosis; Retrospective Studies; Survival Rate; Tissue Distribution

2013
Efficacy of postoperative oxaliplatin- or irinotecan-based chemotherapy after curative resection of synchronous liver metastases from colorectal cancer.
    Anticancer research, 2013, Volume: 33, Issue:8

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Demography; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Organoplatinum Compounds; Oxaliplatin; Postoperative Care; Recurrence; Survival Analysis; Treatment Outcome

2013
Partial response after transcatheter arterial infusion chemotherapy in a patient with systemic chemotherapy-resistant unresectable colon cancer and hepatic metastasis: (case report).
    World journal of surgical oncology, 2013, Aug-17, Volume: 11, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colonic Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Failure; Liver Neoplasms; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Prognosis; Remission Induction; Tomography, X-Ray Computed

2013
[Analysis of therapeutic effect and prognosis in patients with metastatic colorectal cancer and different K-ras status].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2013, Volume: 35, Issue:4

    Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Disease-Free Survival; ErbB Receptors; Female; Follow-Up Studies; Genes, ras; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Mutation; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies; Survival Rate

2013
Modern chemotherapy mitigates adverse prognostic effect of regional nodal metastases in stage IV colorectal cancer.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2014, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Hepatectomy; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Peritoneal Neoplasms; Prognosis; Retrospective Studies; Young Adult

2014
Prognostic significance of visible cardiophrenic angle lymph nodes in the presence of peritoneal metastases from colorectal cancers.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2013, Volume: 39, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Digestive System Surgical Procedures; Female; Humans; Hyperthermia, Induced; Infusions, Parenteral; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Lymph Nodes; Male; Mediastinum; Middle Aged; Multivariate Analysis; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Peritoneal Neoplasms; Predictive Value of Tests; Prognosis; Retrospective Studies; Tomography, X-Ray Computed

2013
Liver resection for colorectal metastases after chemotherapy: impact of chemotherapy-related liver injuries, pathological tumor response, and micrometastases on long-term survival.
    Annals of surgery, 2013, Volume: 258, Issue:5

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Combined Modality Therapy; Fatty Liver; Female; Hepatectomy; Hepatic Veno-Occlusive Disease; Humans; Irinotecan; Liver Neoplasms; Male; Neoplasm Invasiveness; Neoplasm Micrometastasis; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Survival Rate; Treatment Outcome

2013
Liver only metastatic disease in patients with metastatic colorectal cancer: impact of surgery and chemotherapy.
    Acta oncologica (Stockholm, Sweden), 2013, Volume: 52, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Survival Rate

2013
[Preoperative chemotherapy in the surgical treatment of colorectal liver metastases].
    Magyar sebeszet, 2013, Volume: 66, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Folic Acid; Hepatectomy; Hospitals, General; Humans; Irinotecan; Kaplan-Meier Estimate; Length of Stay; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Operative Time; Organoplatinum Compounds; Oxaliplatin; Surgery Department, Hospital; Treatment Outcome

2013
[Multiple hepatic metastases from colon cancer successfully treated with irinotecan and S-1 plus panitumumab as second-line therapy-a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:12

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Drug Combinations; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Panitumumab; Salvage Therapy; Sigmoid Neoplasms; Tegafur

2013
Complete pathological response (ypT0N0M0) after preoperative chemotherapy alone for stage IV rectal cancer.
    BMC surgery, 2014, Jan-17, Volume: 14

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Rectal Neoplasms; Rectum

2014
Interstitial pneumonia during bevacizumab-based chemotherapy for colorectal cancer.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Diseases, Interstitial; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prednisolone; Prognosis; Radiography, Thoracic; Retrospective Studies

2014
Marked antitumor effect of NK012, a SN-38-incorporating micelle formulation, in a newly developed mouse model of liver metastasis resulting from gastric cancer.
    Therapeutic delivery, 2014, Volume: 5, Issue:2

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Female; Genes, Reporter; Humans; Irinotecan; Liver Neoplasms; Luciferases; Luminescent Measurements; Mice; Mice, SCID; Micelles; Stomach Neoplasms; Time Factors; Transfection; Tumor Burden; Xenograft Model Antitumor Assays

2014
Curable patient with metastatic colorectal cancer: balancing effective therapies and toxicities.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Apr-01, Volume: 32, Issue:10

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colectomy; Colonic Neoplasms; Colonoscopy; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Magnetic Resonance Imaging; Neoadjuvant Therapy; Positron-Emission Tomography

2014
Usefulness of contrast-enhanced intraoperative ultrasound in identifying disappearing liver metastases from colorectal carcinoma after chemotherapy.
    Annals of surgical oncology, 2014, Volume: 21 Suppl 3

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colorectal Neoplasms; Combined Modality Therapy; Contrast Media; Female; Follow-Up Studies; Gadolinium DTPA; Hepatectomy; Humans; Intraoperative Care; Irinotecan; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Staging; Neoplasm, Residual; Organoplatinum Compounds; Oxaliplatin; Panitumumab; Prognosis; Retrospective Studies; Survival Rate; Tomography, X-Ray Computed; Ultrasonography, Interventional

2014
[Chemotherapy and targeted therapy in liver metastasis from gastric cancer].
    Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2014, Volume: 17, Issue:2

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Docetaxel; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Molecular Targeted Therapy; Stomach Neoplasms; Taxoids; Trastuzumab

2014
Transarterial treatment of colorectal cancer liver metastases with irinotecan-loaded drug-eluting beads: technical recommendations.
    Journal of vascular and interventional radiology : JVIR, 2014, Volume: 25, Issue:3

    Topics: Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Therapy; Drug-Eluting Stents; Humans; Injections, Intra-Arterial; Internationality; Irinotecan; Liver Neoplasms; Practice Guidelines as Topic

2014
IL-1Ra selectively protects intestinal crypt epithelial cells, but not tumor cells, from chemotoxicity via p53-mediated upregulation of p21(WAF1) and p27(KIP1.).
    Pharmacological research, 2014, Volume: 82

    Topics: Animals; Antimetabolites, Antineoplastic; Camptothecin; Cell Line; Cell Line, Tumor; Colon; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Epithelial Cells; Fluorouracil; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Irinotecan; Jejunum; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mucositis; Protective Agents; Recombinant Proteins; Tumor Suppressor Protein p53; Up-Regulation

2014
Biweekly cetuximab plus FOLFIRI/irinotecan as first/second-line chemotherapy for patients with KRAS wild-type metastatic colorectal cancer: a retrospective analysis in Southwest Chinese population.
    Medical oncology (Northwood, London, England), 2014, Volume: 31, Issue:5

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Asian People; Camptothecin; Cetuximab; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prognosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Retrospective Studies; Salvage Therapy; Survival Rate

2014
A multimarker panel for circulating tumor cells detection predicts patient outcome and therapy response in metastatic colorectal cancer.
    International journal of cancer, 2014, Dec-01, Volume: 135, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Camptothecin; Capecitabine; Cetuximab; Colorectal Neoplasms; Deoxycytidine; Epithelial-Mesenchymal Transition; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Neoplastic Cells, Circulating; Organoplatinum Compounds; Oxaliplatin; Prognosis; Survival Rate

2014
[Trastuzumab combined with chemotherapy in patients with HER2-positive chemo-refractory advanced gastric or gastro-esophageal junction adenocarcinoma].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2014, Volume: 36, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Anorexia; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Disease Progression; Disease-Free Survival; Drug Resistance, Neoplasm; Esophagogastric Junction; Fatigue; Female; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neutropenia; Paclitaxel; Pyrimidines; Receptor, ErbB-2; Remission Induction; Retrospective Studies; Stomach Neoplasms; Survival Rate; Trastuzumab

2014
Biomarkers of reactive resistance and early disease progression during chemotherapy plus bevacizumab treatment for colorectal carcinoma.
    Oncotarget, 2014, May-15, Volume: 5, Issue:9

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Camptothecin; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Disease Progression; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Prognosis; Survival Rate

2014
FOLFIRINOX bevacizumab is a promising therapy for chemorefractory metastatic colorectal cancer.
    Oncology, 2014, Volume: 87, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Prospective Studies; Salvage Therapy; Survival Rate

2014
Progression-free survival remains poor over sequential lines of systemic therapy in patients with BRAF-mutated colorectal cancer.
    Clinical colorectal cancer, 2014, Volume: 13, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Cetuximab; Colorectal Neoplasms; Disease-Free Survival; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Metastasectomy; Microsatellite Instability; Middle Aged; Mutation; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Panitumumab; Peritoneal Neoplasms; Proto-Oncogene Proteins B-raf; Survival Rate

2014
[Neuroendocrine gallbladder cancer treated with cisplatin plus irinotecan - a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Neuroendocrine; Cisplatin; Diagnosis, Differential; Female; Gallbladder Neoplasms; Humans; Irinotecan; Liver Neoplasms; Middle Aged

2014
Fatal outcome of posterior "reversible" encephalopathy syndrome in metastatic colorectal carcinoma after irinotecan and fluoropyrimidine chemotherapy regimen.
    World journal of surgical oncology, 2014, Aug-20, Volume: 12

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Fatal Outcome; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Middle Aged; Neoplasm Staging; Posterior Leukoencephalopathy Syndrome

2014
[Antitumor efficacy of irinotecan-loaded galactosyl modified lipid bilayer-coated mesoporous silica nanoparticles against hepatocellular carcinoma cells].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2014, Volume: 49, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Carcinoma, Hepatocellular; Drug Carriers; Drug Delivery Systems; Humans; Irinotecan; Lipid Bilayers; Liver Neoplasms; Nanoparticles; Particle Size; Silicon Dioxide

2014
Chemotherapy for transarterial chemoembolization in patients with unresectable hepatocellular carcinoma.
    World journal of gastroenterology, 2014, Aug-21, Volume: 20, Issue:31

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Deoxycytidine; Disease Progression; Doxorubicin; Female; Fluorouracil; Gemcitabine; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome

2014
The power of genes: a case of unusually severe systemic toxicity after localized hepatic chemoembolization with irinotecan-eluted microspheres for metastatic colon cancer.
    The Annals of pharmacotherapy, 2014, Volume: 48, Issue:12

    Topics: Aged, 80 and over; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Colonic Neoplasms; Female; Glucuronosyltransferase; Humans; Irinotecan; Liver Neoplasms; Microspheres; Mutation; Neutropenia; Polymorphism, Genetic

2014
CEA change after neoadjuvant chemotherapy including bevacizumab and clinical outcome in patients undergoing liver resection for colorectal liver metastases.
    Annals of surgical oncology, 2015, Volume: 22, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Camptothecin; Carcinoembryonic Antigen; Colorectal Neoplasms; Combined Modality Therapy; Female; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Prospective Studies; Survival Rate

2015
An on-chip small intestine-liver model for pharmacokinetic studies.
    Journal of laboratory automation, 2015, Volume: 20, Issue:3

    Topics: Animals; Caco-2 Cells; Camptothecin; Computer Simulation; Cyclophosphamide; Drug Screening Assays, Antitumor; Epirubicin; Hep G2 Cells; Humans; Intestine, Small; Irinotecan; Lab-On-A-Chip Devices; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Organ Culture Techniques; Stomach Neoplasms

2015
Concomitant capecitabine with hepatic delivery of drug eluting beads in metastatic colorectal cancer.
    Anticancer research, 2014, Volume: 34, Issue:12

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Carriers; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Liver; Liver Neoplasms; Male; Microspheres; Middle Aged

2014
A retrospective analysis of 141 patients with liver metastases from uveal melanoma: a two-cohort study comparing transarterial chemoembolization with CPT-11 charged microbeads and historical treatments.
    Melanoma research, 2015, Volume: 25, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Chemoembolization, Therapeutic; Databases, Factual; Feasibility Studies; Female; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Male; Melanoma; Middle Aged; Proportional Hazards Models; Retrospective Studies; Risk Factors; Treatment Outcome; Uveal Neoplasms; Young Adult

2015
[Complete resection of liver metastases of colorectal cancer after high efficacy bevacizumab, S-1, and CPT -11 combination chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:1

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Combined Modality Therapy; Drug Combinations; Humans; Irinotecan; Liver Neoplasms; Male; Oxonic Acid; Sigmoid Neoplasms; Tegafur

2015
[A case of disease-free, long survival in a patient with mixed adenoneuroendocrine carcinoma of the gallbladder treated with induction CDDP/CPT-11 chemotherapy and resection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Neuroendocrine; Cisplatin; Combined Modality Therapy; Female; Gallbladder Neoplasms; Humans; Irinotecan; Liver Neoplasms; Middle Aged; Time Factors; Treatment Outcome

2015
Targeting cyclin dependent kinase 5 in hepatocellular carcinoma--A novel therapeutic approach.
    Journal of hepatology, 2015, Volume: 63, Issue:1

    Topics: Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Hepatocellular; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Female; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Liver Neoplasms; Mice; Mice, SCID; Purines; RNA, Neoplasm; Roscovitine; Treatment Outcome

2015
Evaluation of the plasmatic and parenchymal elution kinetics of two different irinotecan-loaded drug-eluting embolics in a pig model.
    Journal of vascular and interventional radiology : JVIR, 2015, Volume: 26, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Disease Models, Animal; Female; Irinotecan; Liver Neoplasms; Swine

2015
Hypersensitivity and tumor lysis syndrome associated with cetuximab treatment: should we be afraid?
    Tumori, 2015, Apr-28, Volume: 101, Issue:2

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Bone Neoplasms; Camptothecin; Cetuximab; Colorectal Neoplasms; Drug Hypersensitivity; Emergency Treatment; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Positron-Emission Tomography; Tomography, X-Ray Computed; Treatment Outcome; Tumor Lysis Syndrome

2015
[Mixed adenoneuroendocrine carcinoma with multiple liver metastases successfully treated by cetuximab/CPT-11 chemotherapy followed by curative resection - a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Combined Modality Therapy; Humans; Irinotecan; Liver Neoplasms; Male; Rectal Neoplasms

2014
The Influence of Aging on Hepatic Regeneration and Early Outcome after Portal Vein Occlusion: A Case-Control Study.
    Annals of surgical oncology, 2015, Volume: 22, Issue:12

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biliary Tract Neoplasms; Camptothecin; Case-Control Studies; Chemotherapy, Adjuvant; Diabetes Complications; Embolization, Therapeutic; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Regeneration; Male; Middle Aged; Neoadjuvant Therapy; Organ Size; Organoplatinum Compounds; Oxaliplatin; Portal Vein; Preoperative Care; Radiography; Sex Factors; Young Adult

2015
Transarterial Chemoembolization of Liver Metastases from Uveal Melanoma Using Irinotecan-Loaded Beads: Treatment Response and Complications.
    Cardiovascular and interventional radiology, 2015, Volume: 38, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Contrast Media; Drug Delivery Systems; Female; Humans; Irinotecan; Liver; Liver Neoplasms; Male; Melanoma; Middle Aged; Radiographic Image Enhancement; Retrospective Studies; Therapeutics; Tomography, X-Ray Computed; Uveal Neoplasms; Young Adult

2015
Analyses of multiple factors for determination of "selected patients" who should receive rechallenge treatment in metastatic colorectal cancer: a retrospective study from Turkey.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Patient Selection; Prognosis; Retreatment; Retrospective Studies; Survival Rate; Turkey

2015
Efficacy of bevacizumab and chemotherapy in the first-line treatment of metastatic colorectal cancer: broadening KRAS-focused clinical view.
    BMC gastroenterology, 2015, Mar-24, Volume: 15

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Mutation; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Retrospective Studies; Survival Rate; Young Adult

2015
[Long-term survival and effective treatment of synchronous liver metastases in a case of primary gastric choriocarcinoma by using hepatic arterial infusion chemotherapy, irinotecan, and cisplatin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Choriocarcinoma; Cisplatin; Fatal Outcome; Gastrectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Stomach Neoplasms

2015
Transarterial hepatic chemoembolization with 70-150 µm drug-eluting beads: assessment of clinical safety and liver toxicity profile.
    Journal of vascular and interventional radiology : JVIR, 2015, Volume: 26, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bile Duct Diseases; Camptothecin; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Doxorubicin; Drug Carriers; Female; Humans; Infarction; Irinotecan; Liver Neoplasms; Male; Middle Aged; Particle Size; Patient Safety; Portal Vein; Retrospective Studies; Risk Assessment; Risk Factors; Texas; Time Factors; Treatment Outcome; Tumor Burden; Venous Thrombosis

2015
The use of neo-adjuvant chemotherapy in patients with resectable colorectal liver metastases: Clinical risk score as possible discriminator.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2015, Volume: 41, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Colorectal Neoplasms; Deoxycytidine; Digestive System Surgical Procedures; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Kaplan-Meier Estimate; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Multiple Primary; Organoplatinum Compounds; Oxaliplatin; Predictive Value of Tests; Prognosis; Propensity Score; Retrospective Studies; Risk Assessment; Risk Factors; Treatment Outcome

2015
Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Adult; Camptothecin; Carcinoma, Hepatocellular; Genistein; Glucuronosyltransferase; Humans; Inactivation, Metabolic; Irinotecan; Liver Neoplasms; Male; Metabolic Clearance Rate; Microsomes, Liver; Middle Aged; Propofol; Tamoxifen; Zidovudine

2015
Metastasized pancreatic carcinoma with neoadjuvant FOLFIRINOX therapy and R0 resection.
    World journal of gastroenterology, 2015, May-28, Volume: 21, Issue:20

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Carcinoma, Pancreatic Ductal; Chemotherapy, Adjuvant; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Magnetic Resonance Imaging; Male; Middle Aged; Multimodal Imaging; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Pancreatectomy; Pancreatic Neoplasms; Positron-Emission Tomography; Remission Induction; Tomography, X-Ray Computed; Treatment Outcome; Tumor Burden

2015
Complete pathological response of unresectable liver metastases from colorectal cancer after trans-arterial chemoembolization with drug-eluting beads loaded with irinotecan (DEBIRI) and concomitant systemic FOLFOX: A case report from the FFCD 1201 trial.
    Clinics and research in hepatology and gastroenterology, 2015, Volume: 39, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Drug Carriers; Fluorouracil; Hepatic Artery; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Microspheres; Middle Aged; Organoplatinum Compounds; Prospective Studies; Remission Induction

2015
Defining Eligibility of FOLFIRINOX for First-Line Metastatic Pancreatic Adenocarcinoma (MPC) in the Province of British Columbia: A Population-based Retrospective Study.
    American journal of clinical oncology, 2017, Volume: 40, Issue:6

    Topics: Activities of Daily Living; Adenocarcinoma; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; British Columbia; Camptothecin; Eligibility Determination; Female; Fluorouracil; Humans; Hyperbilirubinemia; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Peritoneal Neoplasms; Renal Insufficiency; Retrospective Studies

2017
Secondary Metastases Resection After Bevacizumab Plus Irinotecan-Based Chemotherapy in First-Line Therapy of Metastatic Colorectal Cancer in a Real-Life Setting: Results of the ETNA Cohort.
    Targeted oncology, 2016, Volume: 11, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cohort Studies; Colorectal Neoplasms; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Male; Metastasectomy; Middle Aged; Neoplasm Staging; Prognosis; Survival Rate

2016
[Occurrence, intratumoral heterogeneity, prognostic and predictive potential of microsatellite instability following surgical resection of primary colorectal carcinomas and corresponding liver metastases].
    Orvosi hetilap, 2015, Sep-06, Volume: 156, Issue:36

    Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Camptothecin; Cetuximab; Colorectal Neoplasms; Disease-Free Survival; DNA Mismatch Repair; Female; Fluorouracil; Genetic Markers; Humans; Irinotecan; Liver Neoplasms; Male; Microsatellite Instability; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Panitumumab; Predictive Value of Tests; Prognosis; Survival Analysis

2015
Long-term survival in small-cell carcinoma of the endometrium with liver and brain metastases.
    Anti-cancer drugs, 2016, Volume: 27, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Carcinoma, Small Cell; Cisplatin; Endometrial Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms

2016
Association of CD133 polymorphisms and response to bevacizumab in patients with metastatic colorectal cancer.
    Cancer biomarkers : section A of Disease markers, 2015, Volume: 15, Issue:6

    Topics: AC133 Antigen; Adult; Aged; Aged, 80 and over; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Camptothecin; Cetuximab; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Glycoproteins; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Peptides; Polymorphism, Genetic; Prognosis; Survival Rate

2015
Fluctuation in Plasma 5-Fluorouracil Concentration During Continuous 5-Fluorouracil Infusion for Colorectal Cancer.
    Anticancer research, 2015, Volume: 35, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Infusions, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Prospective Studies; Survival Rate

2015
Efficacy and Toxicity of Hepatic Intra-Arterial Drug-Eluting (Irinotecan) Bead (DEBIRI) Therapy in Irinotecan-Refractory Unresectable Colorectal Liver Metastases.
    World journal of surgery, 2016, Volume: 40, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Drug Delivery Systems; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver; Liver Neoplasms; Male; Middle Aged; Retrospective Studies; Survival Rate; Treatment Outcome; United States

2016
[Anticancer effect of SN-38 combined with sorafenib on hepatocellular carcinoma in vitro and its mechanism].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2015, Volume: 44, Issue:5

    Topics: Apoptosis; Camptothecin; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Histones; Humans; Irinotecan; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Poly(ADP-ribose) Polymerases; Sorafenib; Tumor Suppressor Protein p53

2015
Gefitinib Synergizes with Irinotecan to Suppress Hepatocellular Carcinoma via Antagonizing Rad51-Mediated DNA-Repair.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA Repair; Drug Resistance, Neoplasm; Drug Synergism; Gefitinib; Hep G2 Cells; Humans; Irinotecan; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Quinazolines; Rad51 Recombinase; RNA, Small Interfering; Topoisomerase I Inhibitors

2016
Singapore Cancer Network (SCAN) Guidelines for Systemic Therapy of Colorectal Cancer.
    Annals of the Academy of Medicine, Singapore, 2015, Volume: 44, Issue:10

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Chemotherapy, Adjuvant; Colectomy; Colorectal Neoplasms; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Metastasectomy; Microsatellite Instability; Organoplatinum Compounds; Oxaliplatin; Panitumumab; Singapore

2015
Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells.
    Oncotarget, 2016, Feb-09, Volume: 7, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Camptothecin; Carcinoma, Hepatocellular; Cell Nucleus; Cell Proliferation; Drug Resistance, Neoplasm; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Immunoenzyme Techniques; Irinotecan; Liver Neoplasms; Mice; Mice, Nude; Phosphoproteins; Protein Transport; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transcription Factors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; YAP-Signaling Proteins

2016
[Pre-Operative Treatment with Transcatheter Arterial Chemoembolization (TACE) and Hepatic Arterial Infusion (HAI) for Liver Metastasis from Gastric Cancer--A Case Report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoembolization, Therapeutic; Combined Modality Therapy; Fluorouracil; Gastrectomy; Hepatectomy; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Stomach Neoplasms

2015
[A Case of Successful Treatment of Metachronous Liver Metastasis from Gastric Cancer with Hepatectomy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Combinations; Gastrectomy; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Oxonic Acid; Stomach Neoplasms; Tegafur; Treatment Outcome

2015
Updated long-term survival for patients with metastatic colorectal cancer treated with liver resection followed by hepatic arterial infusion and systemic chemotherapy.
    Journal of surgical oncology, 2016, Volume: 113, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Dexamethasone; Disease-Free Survival; Female; Floxuridine; Fluorouracil; Follow-Up Studies; Hepatectomy; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Survival Rate; Young Adult

2016
Digital Glissonectomy: A Safe Perihepatic Peritonectomy.
    Annals of surgical oncology, 2016, Volume: 23, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Cytoreduction Surgical Procedures; Female; Humans; Hyperthermia, Induced; Irinotecan; Liver; Liver Neoplasms; Male; Middle Aged; Mitomycin; Organoplatinum Compounds; Oxaliplatin; Peritoneal Neoplasms; Peritoneum; Pseudomyxoma Peritonei; Young Adult

2016
Early Experience with 70-150 μm Irinotecan Drug-eluting Beads (M1-DEBIRI) for the Treatment of Unresectable Hepatic Colorectal Metastases.
    Anticancer research, 2016, Volume: 36, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Delayed-Action Preparations; Disease-Free Survival; Female; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Male; Microspheres; Middle Aged; Retrospective Studies; Treatment Outcome

2016
Hepatic Arterial Infusion of Polyethylene Glycol Drug-eluting Beads for Primary and Metastatic Liver Cancer Therapy.
    Anticancer research, 2016, Volume: 36, Issue:7

    Topics: Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Cholangiocarcinoma; Colorectal Neoplasms; Delayed-Action Preparations; Disease-Free Survival; Doxorubicin; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Microspheres; Middle Aged; Polyethylene Glycols; Retrospective Studies; Treatment Outcome

2016
Hepatic Arterial Infusion in Combination with Modern Systemic Chemotherapy is Associated with Improved Survival Compared with Modern Systemic Chemotherapy Alone in Patients with Isolated Unresectable Colorectal Liver Metastases: A Case-Control Study.
    Annals of surgical oncology, 2017, Volume: 24, Issue:1

    Topics: Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Case-Control Studies; Colorectal Neoplasms; Female; Floxuridine; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Survival Rate; Treatment Outcome

2017
Fractal Dimension of Tc-99m DTPA GSA Estimates Pathologic Liver Injury due to Chemotherapy in Liver Cancer Patients.
    Annals of surgical oncology, 2016, Volume: 23, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Fluorouracil; Fractals; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Predictive Value of Tests; Radionuclide Imaging; Radiopharmaceuticals; Risk Factors; ROC Curve; Technetium Tc 99m Aggregated Albumin; Technetium Tc 99m Pentetate

2016
Chemoembolization with drug eluting beads preloaded with irinotecan (DEBIRI) vs doxorubicin (DEBDOX) as a second line treatment for liver metastases from cholangiocarcinoma: a preliminary study.
    The British journal of radiology, 2016, Volume: 89, Issue:1067

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Bile Duct Neoplasms; Camptothecin; Chemoembolization, Therapeutic; Cholangiocarcinoma; Contrast Media; Doxorubicin; Drug Delivery Systems; Female; Humans; Irinotecan; Liver Neoplasms; Male; Tomography, X-Ray Computed; Treatment Outcome

2016
Effectiveness and safety of aflibercept for metastatic colorectal cancer: retrospective review within an early access program in Spain.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2017, Volume: 19, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease Progression; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Peritoneal Neoplasms; Prognosis; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Retrospective Studies; Spain; Survival Rate

2017
The role of thymidylate synthase in non-small cell lung cancer treated with pemetrexed continuation maintenance therapy.
    Journal of chemotherapy (Florence, Italy), 2017, Volume: 29, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cetuximab; Cisplatin; Disease Progression; Female; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Pemetrexed; Phenylurea Compounds; Prognosis; Pyridines; Retrospective Studies; Survival Rate; Thymidylate Synthase

2017
Chemotherapy rechallenge after regorafenib treatment in metastatic colorectal cancer: still hope after the last hope?
    Journal of chemotherapy (Florence, Italy), 2017, Volume: 29, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colorectal Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Phenylurea Compounds; Prognosis; Pyridines; Retrospective Studies; Survival Rate

2017
ERK activation and autophagy impairment are central mediators of irinotecan-induced steatohepatitis.
    Gut, 2018, Volume: 67, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Autophagy; Camptothecin; Disease Models, Animal; Fatty Liver; Hepatocytes; Humans; In Vitro Techniques; Irinotecan; Liver Neoplasms; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Preoperative Care

2018
Cetuximab strongly enhances immune cell infiltration into liver metastatic sites in colorectal cancer.
    Cancer science, 2017, Volume: 108, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; CD3 Complex; CD56 Antigen; CD8 Antigens; Cetuximab; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Humans; Inflammation; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaloacetates

2017
Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer.
    BMC cancer, 2017, 01-11, Volume: 17, Issue:1

    Topics: Aged; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; DNA Topoisomerases, Type I; Female; Gene Dosage; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Treatment Outcome

2017
[A Case of Multiple Liver Metastasis from Gastric Cancer Successfully Treated with CPT-11 as Third-Line Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Combined Modality Therapy; Fatal Outcome; Gastrectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Stomach Neoplasms; Time Factors

2016
Third-line treatment of colorectal liver metastases using DEBIRI chemoembolization.
    Medical oncology (Northwood, London, England), 2017, Volume: 34, Issue:3

    Topics: Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Retrospective Studies

2017
Characterization of a novel intrinsically radiopaque Drug-eluting Bead for image-guided therapy: DC Bead LUMI™.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, 03-28, Volume: 250

    Topics: Animals; Antineoplastic Agents; Benzaldehydes; Camptothecin; Cell Line, Tumor; Chemoembolization, Therapeutic; Delayed-Action Preparations; Doxorubicin; Drug Carriers; Drug Liberation; Female; Humans; Iodobenzenes; Ion Exchange; Irinotecan; Liver Neoplasms; Microspheres; Optical Imaging; Particle Size; Polyvinyl Alcohol; Rabbits; Surface Properties; Tomography, X-Ray Computed

2017
Dasatinib synergises with irinotecan to suppress hepatocellular carcinoma via inhibiting the protein synthesis of PLK1.
    British journal of cancer, 2017, Apr-11, Volume: 116, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Camptothecin; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Proliferation; Dasatinib; Drug Synergism; Female; Flow Cytometry; Humans; Irinotecan; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Polo-Like Kinase 1; Protein Biosynthesis; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2017
Molecular subtypes of metastatic colorectal cancer are associated with patient response to irinotecan-based therapies.
    European journal of cancer (Oxford, England : 1990), 2017, Volume: 76

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Prognosis; Survival Rate; Transcriptome; Treatment Outcome

2017
[A case of interstitial pneumonia induced by S-1/irinotecan combination therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Combinations; Humans; Irinotecan; Liver Neoplasms; Lung Diseases, Interstitial; Male; Oxonic Acid; Tegafur; Tomography, X-Ray Computed; Treatment Failure

2008
[A case of Stage IV gastric cancer with liver and peritoneal metastases responding completely to tailored S-1/CPT- 11 combination therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Drug Combinations; Gastroscopy; Humans; Irinotecan; Liver Neoplasms; Male; Neoplasm Staging; Oxonic Acid; Peritoneal Neoplasms; Stomach Neoplasms; Tegafur; Tomography, X-Ray Computed

2008
Multiagent chemotherapy for isolated colorectal liver metastases: a single-centered retrospective study.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2009, Volume: 13, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colorectal Neoplasms; Disease-Free Survival; ErbB Receptors; Female; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Prodrugs; Retrospective Studies; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Vascular Endothelial Growth Factor A

2009
An autopsy case of acute pulmonary toxicity related to irinotecan.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2008, Volume: 10, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Phytogenic; Autopsy; Camptothecin; Carcinoma, Squamous Cell; Fatal Outcome; Humans; Irinotecan; Laryngeal Neoplasms; Liver Neoplasms; Lung; Lung Neoplasms; Male; Neoplasm Staging; Radiography, Thoracic; Respiratory Distress Syndrome; Sigmoid Neoplasms; Tomography, X-Ray Computed

2008
[Three cases with liver metastasis from gastric or colon cancer successfully treated with S-1 combined with CPT- 11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:9

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Combinations; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Stomach Neoplasms; Tegafur; Tomography, X-Ray Computed

2008
A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer.
    Cancer chemotherapy and pharmacology, 2009, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Disease-Free Survival; Dose-Response Relationship, Drug; Feasibility Studies; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Pleural Neoplasms; Survival Rate; Treatment Outcome; Young Adult

2009
Impact of baseline sum of longest diameter in target lesions by RECIST on survival of patients with metastatic colorectal cancer.
    Japanese journal of clinical oncology, 2008, Volume: 38, Issue:10

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Peritoneal Neoplasms; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome

2008
Pathologic response to preoperative chemotherapy: a new outcome end point after resection of hepatic colorectal metastases.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Nov-20, Volume: 26, Issue:33

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Survival Rate

2008
Preoperative chemotherapy does not increase morbidity or mortality of hepatic resection for colorectal cancer metastases.
    Annals of surgical oncology, 2009, Volume: 16, Issue:1

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Colectomy; Colorectal Neoplasms; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Morbidity; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Prognosis; Prospective Studies; Retrospective Studies; Survival Rate; Thalidomide; Treatment Outcome

2009
[A case of metastatic lung and liver tumors from rectal cancer treated with oral UFT and CPT-11 by hepatic arterial infusion followed by FOLFOX and FOLFIRI].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:11

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Rectal Neoplasms; Tegafur; Tomography, X-Ray Computed; Uracil

2008
Synchronous hepatic metastases from colon cancer: changing treatment strategies and results of surgical intervention.
    Annals of surgical oncology, 2009, Volume: 16, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Carcinoembryonic Antigen; Colonic Neoplasms; Combined Modality Therapy; Female; Humans; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome

2009
Repeated transarterial chemoembolization in the treatment of liver metastases of colorectal cancer: prospective study.
    Radiology, 2009, Volume: 250, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Deoxycytidine; Disease Progression; Female; Gemcitabine; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Mitomycin; Palliative Care; Prospective Studies; Survival Rate; Tomography, Spiral Computed

2009
A dilemma in geriatric oncology: malignant bowel obstruction in an 81-year-old man.
    Cancer treatment reviews, 2008, Volume: 34 Suppl 2

    Topics: Adenocarcinoma; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Fluorouracil; Humans; Intestinal Obstruction; Irinotecan; Liver Neoplasms; Male; Organoplatinum Compounds; Oxaliplatin

2008
[Third-line treatment of intermittent hepatic arterial infusion for unresectable liver metastases from colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Salvage Therapy

2008
[A case of unresectable advanced gastric cancer successfully treated with continuous S-1 + CPT-11 chemotherapy accompanied by dose reduction against grade 4 hematological adverse event].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Blood Cell Count; Camptothecin; Cell Proliferation; Drug Combinations; Gastroscopy; Humans; Irinotecan; Liver Neoplasms; Magnetic Resonance Imaging; Male; Neoplasm Staging; Oxonic Acid; Stomach Neoplasms; Tegafur

2008
[A case of advanced sigmoid colon cancer performed resection of liver metastases after long-term control by S-1 and CPT-11 combination chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoembryonic Antigen; Drug Combinations; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Oxonic Acid; Positron-Emission Tomography; Sigmoid Neoplasms; Tegafur; Time Factors; Tomography, X-Ray Computed

2008
[A case of simultaneous double cancers with multiple liver metastases responding to S-1+CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Carcinoembryonic Antigen; Drug Combinations; Endoscopy, Gastrointestinal; Humans; Irinotecan; Liver Neoplasms; Male; Neoplasms, Multiple Primary; Oxonic Acid; Rectal Neoplasms; Stomach Neoplasms; Tegafur; Tomography, X-Ray Computed; Treatment Outcome

2009
Can cetuximab affect paraneoplastic myopathy?
    Journal of neuro-oncology, 2009, Volume: 93, Issue:3

    Topics: Adenocarcinoma; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Candidiasis; Cetuximab; Colonic Neoplasms; Humans; Irinotecan; Klebsiella Infections; Liver Neoplasms; Male; Methylprednisolone; Middle Aged; Muscular Diseases; Paraneoplastic Syndromes; Tuberculosis

2009
[A case of recurrence after curative total gastrectomy for gastric cancer successfully treated by combination chemotherapy with CPT-11 and CDDP].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Gastrectomy; Humans; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Male; Neoplasm Staging; Positron-Emission Tomography; Recurrence; Remission Induction; Stomach Neoplasms; Tomography, X-Ray Computed

2009
Is there a survival benefit to neoadjuvant versus adjuvant chemotherapy, combined with surgery for resectable colorectal liver metastases?
    World journal of surgery, 2009, Volume: 33, Issue:5

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Hepatectomy; Humans; Irinotecan; Liver; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies; Survival Analysis; Treatment Outcome

2009
Successful and well-tolerated second line therapy with cetuximab, irinotecan, and raltitrexed in progressive liver disease due to metastatic colon cancer.
    Journal of gastrointestinal cancer, 2008, Volume: 39, Issue:1-4

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colonic Neoplasms; Humans; Irinotecan; Liver Diseases; Liver Neoplasms; Male; Quinazolines; Thiophenes

2008
Conversion to resectability using hepatic artery infusion plus systemic chemotherapy for the treatment of unresectable liver metastases from colorectal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Jul-20, Volume: 27, Issue:21

    Topics: Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Dexamethasone; Female; Floxuridine; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Mastectomy, Segmental; Organoplatinum Compounds; Oxaliplatin; Treatment Outcome

2009
Radiofrequency ablation of colorectal liver metastases downstaged by chemotherapy.
    Acta radiologica (Stockholm, Sweden : 1987), 2009, Volume: 50, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Catheter Ablation; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies; Survival Rate; Time Factors; Tomography, X-Ray Computed; Treatment Outcome

2009
[Two cases of KRAS wild-type unresectable or recurrent colorectal cancer effectively treated by cetuximab after progression of prior chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:6

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Cetuximab; Colorectal Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins

2009
Radioembolization of liver metastases in patients with colorectal cancer: a nonsurgical treatment with combined modality potential.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Antimetabolites, Antineoplastic; Brachytherapy; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Enzyme Inhibitors; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Maximum Tolerated Dose; Microspheres; Radiopharmaceuticals; Radiotherapy, Adjuvant; Time Factors; Topoisomerase I Inhibitors; Treatment Outcome; Yttrium Isotopes

2009
[Clinical significance of a transient increase in carcinoembryonic antigen and carbohydrate antigen 19-9 in patients with metastatic colorectal cancer receiving chemotherapy].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:9

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Camptothecin; Capecitabine; Carcinoembryonic Antigen; Child; Colonic Neoplasms; Deoxycytidine; Disease Progression; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Rectal Neoplasms; Remission Induction; Young Adult

2009
Long-term outcome of unresectable metastatic colorectal cancer: does "adjuvant" chemotherapy play a role after resection?
    Annals of surgery, 2009, Volume: 250, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Pneumonectomy; Survival Rate; Treatment Outcome

2009
[A case of recurrent gastric cancer during adjuvant chemotherapy with S-1, treated by S-1 combination chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:10

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Cisplatin; Drug Combinations; Fatal Outcome; Gastrectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Oxonic Acid; Paclitaxel; Recurrence; Stomach Neoplasms; Tegafur; Tomography, X-Ray Computed

2009
Advanced hepatocellular carcinoma treated effectively with irinotecan via hepatic arterial infusion followed by proton beam therapy.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2009, Volume: 15, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Combined Modality Therapy; Humans; Hyperthermia, Induced; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Proton Therapy; Survivors

2009
MDR1 polymorphism role in patients treated with cetuximab and irinotecan in irinotecan refractory colorectal cancer.
    Medical oncology (Northwood, London, England), 2010, Volume: 27, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Cetuximab; Colorectal Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Female; Humans; Immunoenzyme Techniques; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Polymorphism, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Survival Rate; Treatment Outcome

2010
[A successful two-stage treatment with CDDP and CPT-11 for pancreatic neuroendocrine carcinoma with liver metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:11

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Neuroendocrine; Cisplatin; Combined Modality Therapy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms

2009
Irinotecan and mismatch repair deficiency.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Camptothecin; Carcinoma; Colorectal Neoplasms; DNA Mismatch Repair; DNA Repair-Deficiency Disorders; Drug Resistance, Neoplasm; Humans; Irinotecan; Liver Neoplasms; Postoperative Period; Prognosis

2010
[Efficacy of cetuximab combined with chemotherapy on advanced colorectal cancer: a report of 53 cases].
    Ai zheng = Aizheng = Chinese journal of cancer, 2009, Volume: 28, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colonic Neoplasms; Combined Modality Therapy; Diarrhea; Exanthema; Female; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neutropenia; Organoplatinum Compounds; Oxaliplatin; Prognosis; Proportional Hazards Models; Rectal Neoplasms; Remission Induction; Retrospective Studies

2009
[A case of interstitial pneumonitis induced by FOLFIRI+bevacizumab combination therapy for liver and lung metastasis of colon cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:13

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Diseases, Interstitial; Lung Neoplasms; Middle Aged; Sigmoid Neoplasms

2009
Evidence of heterogeneity within colorectal liver metastases for allelic losses, mRNA level expression and in vitro response to chemotherapeutic agents.
    International journal of cancer, 2010, Sep-01, Volume: 127, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Genetic Variation; Humans; In Vitro Techniques; Irinotecan; Liver Neoplasms; Loss of Heterozygosity; Polyhydroxyethyl Methacrylate; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Topoisomerase I Inhibitors

2010
[A case report of metastatic liver tumor from rectosigmoid colon cancer demonstrating a pathological complete response with FOLFOX and FOLFIRI treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Organoplatinum Compounds; Rectal Neoplasms; Sigmoid Neoplasms

2009
[Intermittent hepatic arterial infusion with systemic chemotherapy for metastatic colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Hepatic Artery; Humans; Infusions, Intra-Arterial; Injections, Intravenous; Irinotecan; Liver Neoplasms; Middle Aged

2009
[A case report of multiple liver metastases from colorectal cancer effectively treated with systemic chemotherapy and hepatic arterial infusion].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Hepatectomy; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Sigmoid Neoplasms; Tegafur; Uracil

2009
[A curative resection with the combination of portal vein branch embolization and systemic chemotherapy in a patient with synchronous multiple and bilobar colorectal liver metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Embolization, Therapeutic; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Portal Vein

2009
Tumor marker evolution: comparison with imaging for assessment of response to chemotherapy in patients with colorectal liver metastases.
    Annals of surgical oncology, 2010, Volume: 17, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; CA-19-9 Antigen; Camptothecin; Carcinoembryonic Antigen; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Survival Rate; Tomography, X-Ray Computed; Treatment Outcome

2010
Irinotecan as maintenance therapy in high-risk hepatoblastoma.
    Pediatric blood & cancer, 2010, Volume: 54, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Child, Preschool; Disease-Free Survival; Hepatoblastoma; Humans; Infant; Irinotecan; Liver Neoplasms

2010
Coexpression of biological key modulators in primary colorectal carcinomas and related metastatic sites: implications for treatment with cetuximab.
    Bulletin du cancer, 2010, Volume: 97, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Biomarkers, Tumor; Camptothecin; Cetuximab; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; ErbB Receptors; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Vascular Endothelial Growth Factor A

2010
[Successful treatment with S-1 + CPT-11 for hepatic metastasis from gastric cancer--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Combinations; Gastrectomy; Humans; Irinotecan; Liver Neoplasms; Male; Oxonic Acid; Stomach Neoplasms; Tegafur

2010
[A case of advanced rectal cancer with liver and lung metastasis showing a complete response by neo-adjuvant FOLFOX4 chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Rectal Neoplasms

2010
[Liver metastasis from sigmoid colon cancer showed a complete response to S-1 after recurrence with FOLFOX6 treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Combinations; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Oxonic Acid; Sigmoid Neoplasms; Tegafur

2010
[Prognostic analysis of patients with liver metastases from colorectal cancer treated with different modes of therapy].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2010, Volume: 32, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Female; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Proportional Hazards Models; Retrospective Studies; Survival Rate; Young Adult

2010
Chemotherapy of advanced small-bowel adenocarcinoma: a multicenter AGEO study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Duodenal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Ileal Neoplasms; Intestine, Small; Irinotecan; Jejunal Neoplasms; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Peritoneal Neoplasms; Prognosis; Retrospective Studies; Survival Rate

2010
[A case of small cell lung cancer (extensive disease) with liver metastasis acquiring stable disease by hepatic arterial infusion chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Cisplatin; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Small Cell Lung Carcinoma

2010
[Prognostic factors and survival of metastatic colorectal cancer in the Sousse University Hospital (Tunisia): comparative study of two treatment period of 200 patients].
    Bulletin du cancer, 2010, Volume: 97, Issue:4

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Ovarian Neoplasms; Peritoneal Neoplasms; Prognosis; Retrospective Studies; Survival Rate; Tunisia; Young Adult

2010
Choroidal metastases from esophageal adenocarcinoma responding to chemotherapy with cisplatin and irinotecan.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Aug-01, Volume: 28, Issue:22

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Choroid Neoplasms; Cisplatin; Esophageal Neoplasms; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged

2010
Neoadjuvant chemotherapy in patients with stage IV colorectal cancer: a comparison of histological response in liver metastases, primary tumors, and regional lymph nodes.
    Annals of surgical oncology, 2010, Volume: 17, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Survival Rate; Treatment Outcome

2010
[A case of fluoropyrimidine-resistant recurrent colon cancer successfully treated with weekly administration of irinotecan].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoembryonic Antigen; Colonic Neoplasms; Drug Resistance, Neoplasm; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Neoplasm Staging; Recurrence; Tegafur; Tomography, X-Ray Computed; Uracil

2010
Chemotherapy-induced liver injury in metastatic colorectal cancer: semiquantitative histologic analysis of 334 resected liver specimens shows that vascular injury but not steatohepatitis is associated with preoperative chemotherapy.
    The American journal of surgical pathology, 2010, Volume: 34, Issue:6

    Topics: Antineoplastic Agents; Camptothecin; Chemical and Drug Induced Liver Injury; Colorectal Neoplasms; Fatty Liver; Female; Humans; Irinotecan; Liver Circulation; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies

2010
Recovery of liver function after the cessation of preoperative chemotherapy for colorectal liver metastasis.
    Annals of surgical oncology, 2010, Volume: 17, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Hepatectomy; Humans; Indocyanine Green; Irinotecan; Leucovorin; Liver; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Prospective Studies; Recovery of Function; Survival Rate; Time Factors; Treatment Outcome

2010
Surgical downstaging and neo-adjuvant therapy in metastatic colorectal carcinoma with irinotecan drug-eluting beads: a multi-institutional study.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2010, Volume: 12, Issue:1

    Topics: Adult; Aged; Alabama; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma; Catheter Ablation; Chemoembolization, Therapeutic; Chemotherapy, Adjuvant; Chi-Square Distribution; Colorectal Neoplasms; Czech Republic; Female; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Kentucky; Liver Neoplasms; Male; Microspheres; Middle Aged; Neoadjuvant Therapy; Positron-Emission Tomography; Proportional Hazards Models; Prospective Studies; Registries; Tomography, X-Ray Computed; Treatment Outcome

2010
Perioperative chemotherapy with bevacizumab and liver resection for colorectal cancer liver metastasis.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2010, Volume: 12, Issue:1

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Hepatectomy; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Positron-Emission Tomography; Quebec; Retrospective Studies; Time Factors; Tomography, X-Ray Computed; Treatment Outcome

2010
Adjuvant oxaliplatin- or irinotecan-containing chemotherapy improves overall survival following resection of metachronous colorectal liver metastases.
    International journal of colorectal disease, 2010, Volume: 25, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies; Survival Rate; Treatment Outcome

2010
Tumor thickness at the tumor-normal interface: a novel pathologic indicator of chemotherapy response in hepatic colorectal metastases.
    The American journal of surgical pathology, 2010, Volume: 34, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Retrospective Studies

2010
[A case of gastric adenosquamous carcinoma successfully treated with second-line chemotherapy (CPT-11 and CDDP)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Adenosquamous; Cisplatin; Gastrectomy; Humans; Irinotecan; Liver Neoplasms; Male; Neoadjuvant Therapy; Positron-Emission Tomography; Remission Induction; Stomach Neoplasms; Tomography, X-Ray Computed

2010
Hepatic intra-arterial injection of drug-eluting bead, irinotecan (DEBIRI) in unresectable colorectal liver metastases refractory to systemic chemotherapy: results of multi-institutional study.
    Annals of surgical oncology, 2011, Volume: 18, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Cohort Studies; Colorectal Neoplasms; Drug Delivery Systems; Feasibility Studies; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Salvage Therapy; Survival Rate; Treatment Outcome

2011
Acute thrombocytopenia: an unusual complication occurring after drug-eluting microspheres transcatheter hepatic chemoembolization.
    Cardiovascular and interventional radiology, 2011, Volume: 34 Suppl 2

    Topics: Acute Disease; Adenocarcinoma; Antineoplastic Agents; Camptothecin; Chemoembolization, Therapeutic; Colonic Neoplasms; Follow-Up Studies; Humans; Irinotecan; Leukocyte Count; Liver Neoplasms; Male; Microspheres; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Platelet Count; Sigmoid Neoplasms; Thrombocytopenia

2011
Cetuximab plus chronomodulated irinotecan, 5-fluorouracil, leucovorin and oxaliplatin as neoadjuvant chemotherapy in colorectal liver metastases: POCHER trial.
    British journal of cancer, 2010, Nov-09, Volume: 103, Issue:10

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Diarrhea; Disease-Free Survival; ErbB Receptors; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Research Design; Survival Rate; Tomography, X-Ray Computed

2010
Regenerative nodular hyperplasia of the liver related to chemotherapy: impact on outcome of liver surgery for colorectal metastases.
    Annals of surgical oncology, 2011, Volume: 18, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Focal Nodular Hyperplasia; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Survival Rate; Treatment Outcome

2011
[Efficacy of cetuximab combined with chemotherapy for patients with advanced colorectal cancer and unclear K-ras status].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2010, Volume: 32, Issue:10

    Topics: Acneiform Eruptions; Adenocarcinoma; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colonic Neoplasms; Diarrhea; Disease-Free Survival; Female; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neutropenia; Organoplatinum Compounds; Oxaliplatin; ras Proteins; Rectal Neoplasms; Remission Induction; Survival Rate

2010
Evaluation of chemotherapy-associated liver injury in patients with colorectal cancer liver metastases using indocyanine green clearance testing.
    Annals of surgical oncology, 2011, Volume: 18, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemical and Drug Induced Liver Injury; Colorectal Neoplasms; Female; Fluorouracil; Humans; Indocyanine Green; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Survival Rate; Treatment Outcome

2011
A patient with metastatic colon cancer to the liver presenting with cardiac arrest status post receiving combination irinotecan-panitumumab: a case report.
    Journal of experimental therapeutics & oncology, 2010, Volume: 8, Issue:4

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Heart Arrest; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Panitumumab

2010
[A case of gastric endocrine cell carcinoma with liver metastases treated with S-1/CDDP].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Combinations; Endocrine Gland Neoplasms; Gastrectomy; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Oxonic Acid; Stomach Neoplasms; Tegafur; Treatment Outcome

2010
[A case of multiple lung and liver metastases from colon cancer treated with clinical benefit by hepatic arterial infusion chemotherapy plus cetuximab mono-therapy after standard chemotherapy failure].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Carcinoembryonic Antigen; Cetuximab; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Middle Aged; Organoplatinum Compounds; Sigmoid Neoplasms

2010
[A case of recurrent sigmoid colon cancer with adrenal and para-aortic lymph node metastasis successfully treated by operation and chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Aorta; Bevacizumab; Camptothecin; Combined Modality Therapy; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Sigmoid Neoplasms; Tegafur; Uracil

2010
[Hepatic resection after systemic chemotherapy for liver metastasis of colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colorectal Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Hepatectomy; Humans; Irinotecan; Length of Stay; Liver Neoplasms; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Tegafur; Uracil

2010
[A case of unresectable multiple hepatic metastases from colorectal cancer successfully treated with IRIS (S-1, CPT-11) therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Combinations; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Oxonic Acid; Tegafur; Tumor Burden

2010
Transcatheter arterial chemoembolization with docetaxel-loaded microspheres controls heavily pretreated unresectable liver metastases from colorectal cancer: a case study.
    International journal of clinical oncology, 2011, Volume: 16, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Docetaxel; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Microspheres; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Taxoids

2011
R1 resection for aggressive or advanced colorectal liver metastases is justified in combination with effective prehepatectomy chemotherapy.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2011, Volume: 37, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Cisplatin; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies; Survival Analysis; Treatment Outcome

2011
Retrospective cohort study on the safety and efficacy of bevacizumab with chemotherapy for metastatic colorectal cancer patients: the HGCSG0801 study.
    Japanese journal of clinical oncology, 2011, Volume: 41, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cohort Studies; Colorectal Neoplasms; Confidence Intervals; Disease-Free Survival; Drug Administration Schedule; Drug Combinations; Epistaxis; Female; Fluorouracil; Gastrointestinal Hemorrhage; Humans; Hypertension; Irinotecan; Japan; Kaplan-Meier Estimate; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxonic Acid; Proteinuria; Retrospective Studies; Tegafur; Thrombosis; Treatment Outcome

2011
Capecitabine monotherapy as salvage treatment after failure of chemotherapy containing oxaliplatin and irinotecan in patients with metastatic colorectal cancer.
    Asia-Pacific journal of clinical oncology, 2011, Volume: 7, Issue:1

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Capecitabine; Child; Child, Preschool; Colorectal Neoplasms; Deoxycytidine; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Infant; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Peritoneal Neoplasms; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Rate; Treatment Outcome; Young Adult

2011
Improvement of oral intake following chemotherapy in gastric cancer patients with an inability to eat.
    Oncology, 2010, Volume: 79, Issue:3-4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Feeding and Eating Disorders; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Male; Peritoneal Neoplasms; Retrospective Studies; Stomach Neoplasms; Survival Rate; Taxoids; Treatment Outcome

2010
Is resection of colorectal liver metastases after a second-line chemotherapy regimen justified?
    Cancer, 2011, Oct-01, Volume: 117, Issue:19

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Postoperative Complications; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome

2011
Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan.
    Gastroenterology, 2011, Volume: 141, Issue:1

    Topics: Adenocarcinoma; Aldehyde Dehydrogenase; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers, Tumor; Blotting, Western; Camptothecin; Cell Differentiation; Colonic Neoplasms; Cyclosporins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Irinotecan; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Spheroids, Cellular; Time Factors; Topoisomerase I Inhibitors; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2011
Bevacizumab in combination with cetuximab and irinotecan after failure of cetuximab and irinotecan in patients with metastatic colorectal cancer.
    Acta oncologica (Stockholm, Sweden), 2011, Volume: 50, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colorectal Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Retrospective Studies; Survival Rate; Treatment Outcome

2011
[A resected case of advanced gastric cancer with multiple liver metastasis successfully treated by preoperative and postoperative S-1/CPT-11 combination chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Combined Modality Therapy; Drug Combinations; Humans; Irinotecan; Liver Neoplasms; Lymph Node Excision; Male; Oxonic Acid; Remission Induction; Stomach Neoplasms; Tegafur; Tomography, X-Ray Computed

2011
Safe use of FOLFOX in two patients with metastatic colorectal carcinoma and severe hepatic dysfunction.
    Clinical colorectal cancer, 2011, Mar-01, Volume: 10, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bilirubin; Camptothecin; Colorectal Neoplasms; Disease Progression; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Organoplatinum Compounds; Oxaliplatin

2011
Bevacizumab in first-line therapy of metastatic colorectal cancer: a retrospective comparison of FOLFIRI and XELIRI.
    Anticancer research, 2011, Volume: 31, Issue:5

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Disease Progression; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Retrospective Studies; Survival Rate; Treatment Outcome; Vascular Endothelial Growth Factor A

2011
The status of EGFR-associated genes could predict the outcome and tumor response of chemo-refractory metastatic colorectal patients using cetuximab and chemotherapy.
    Journal of surgical oncology, 2011, Nov-01, Volume: 104, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Class I Phosphatidylinositol 3-Kinases; Colorectal Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Mutation; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins B-raf; PTEN Phosphohydrolase; Retrospective Studies; Salvage Therapy; Survival Rate; Treatment Outcome

2011
Quinacrine sensitizes hepatocellular carcinoma cells to TRAIL and chemotherapeutic agents.
    Cancer biology & therapy, 2011, Aug-01, Volume: 12, Issue:3

    Topics: Animals; Antineoplastic Agents; Benzenesulfonates; Camptothecin; Carcinoma, Hepatocellular; Cell Death; Cell Nucleus; Cytoplasm; Deoxycytidine; Doxorubicin; Drug Synergism; Etoposide; Female; Fluorouracil; Gemcitabine; Genes, p53; Humans; Irinotecan; Liver Neoplasms; Mice; Microtubule-Associated Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Niacinamide; Phenylurea Compounds; Proto-Oncogene Proteins c-bcl-2; Pyridines; Quinacrine; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA, Small Interfering; Sorafenib; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2011
[A case of advanced gastric cancer with multiple liver metastasis responding to S-1 and irinotecan combination therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Drug Combinations; Fatal Outcome; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Oxonic Acid; Stomach Neoplasms; Tegafur

2011
Durable complete responses in metastatic colorectal cancer treated with chemotherapy alone.
    Clinical colorectal cancer, 2011, Volume: 10, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cohort Studies; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Remission Induction; Retrospective Studies; Survival Rate; Treatment Outcome

2011
Outcome and natural history of patients with stage IV colorectal cancer receiving chemotherapy without primary tumor resection.
    Annals of surgical oncology, 2012, Volume: 19, Issue:2

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Peritoneal Neoplasms; Prospective Studies; Retrospective Studies; Survival Rate; Treatment Outcome

2012
Outcome of second-line treatment after first-line chemotherapy with the GONO FOLFOXIRI regimen.
    Clinical colorectal cancer, 2012, Volume: 11, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Mitomycin; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Salvage Therapy; Survival Rate; Treatment Outcome

2012
Chemotherapy between the first and second stages of a two-stage hepatectomy for colorectal liver metastases: should we routinely recommend it?
    Annals of surgical oncology, 2012, Volume: 19, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Premedication; Survival Rate

2012
Peri-operative chemotherapy for resectable colorectal liver metastasis: does timing of systemic therapy matter?
    Journal of surgical oncology, 2012, Volume: 105, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Female; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Matched-Pair Analysis; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Postoperative Complications; Propensity Score; Young Adult

2012
Whole abdominopelvic intensity-modulated radiation therapy for desmoplastic small round cell tumor after surgery.
    International journal of radiation oncology, biology, physics, 2012, May-01, Volume: 83, Issue:1

    Topics: Abdominal Neoplasms; Adolescent; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Desmoplastic Small Round Cell Tumor; Erythrocyte Transfusion; Feasibility Studies; Humans; Hyperthermia, Induced; Interferons; Irinotecan; Liver Neoplasms; Male; Pelvic Neoplasms; Peritoneal Neoplasms; Radiation-Sensitizing Agents; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Retrospective Studies; Temozolomide; Thrombocytopenia; Vinblastine; Vinorelbine; Young Adult

2012
Analysis of HER-3, insulin growth factor-1, nuclear factor-kB and epidermal growth factor receptor gene copy number in the prediction of clinical outcome for K-RAS wild-type colorectal cancer patients receiving irinotecan-cetuximab.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; Disease-Free Survival; DNA Mutational Analysis; ErbB Receptors; Female; Gene Dosage; Humans; Insulin-Like Growth Factor I; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Logistic Models; Male; Middle Aged; Multivariate Analysis; NF-kappa B; Proportional Hazards Models; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Receptor, ErbB-3; Retrospective Studies; Treatment Outcome

2012
Contrast-enhanced ultrasonography with intraarterial administration of SonoVue for guidance of transarterial chemoembolization: an initial experience.
    Medical ultrasonography, 2011, Volume: 13, Issue:4

    Topics: Aged; Aged, 80 and over; Angiography, Digital Subtraction; Camptothecin; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cholangiocarcinoma; Contrast Media; Doxorubicin; Feasibility Studies; Female; Humans; Injections, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Microspheres; Middle Aged; Phospholipids; Prospective Studies; Sulfur Hexafluoride; Treatment Outcome; Ultrasonography, Interventional

2011
Outcomes of resection for colorectal cancer hepatic metastases stratified by evolving eras of treatment.
    World journal of surgical oncology, 2011, Dec-30, Volume: 9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Prognosis; Retrospective Studies; Survival Rate; Time Factors; Treatment Outcome; Young Adult

2011
Development of a combination drug-eluting bead: towards enhanced efficacy for locoregional tumour therapies.
    Anti-cancer drugs, 2012, Volume: 23, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Doxorubicin; Humans; Irinotecan; Liver Neoplasms; Mice; Mice, Nude; Pancreatic Neoplasms; Prostheses and Implants; Sirolimus; Topotecan; Xenograft Model Antitumor Assays

2012
Viewing metastatic colorectal cancer as a curable chronic disease.
    American journal of clinical oncology, 2012, Volume: 35, Issue:1

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Attitude of Health Personnel; Bevacizumab; Camptothecin; Cetuximab; Chronic Disease; Colorectal Neoplasms; Humans; Irinotecan; Liver Neoplasms; Metastasectomy; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Patient Selection; Recurrence; Reoperation; Survival Rate

2012
Hypoxia-inducible factor-1α and excision repair cross-complementing 1 in patients with small cell lung cancer who received front-line platinum-based chemotherapy: a retrospective study.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2012, Volume: 7, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Brain Neoplasms; Camptothecin; Carboplatin; Cisplatin; DNA-Binding Proteins; Endonucleases; Etoposide; Female; Follow-Up Studies; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoenzyme Techniques; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Small Cell Lung Carcinoma; Survival Rate

2012
Intraoperative detection of disappearing colorectal liver metastases as a predictor of residual disease.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2012, Volume: 16, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma; Chi-Square Distribution; Colorectal Neoplasms; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Multivariate Analysis; Neoplasm, Residual; Organoplatinum Compounds; Oxaliplatin; Positron-Emission Tomography; Proportional Hazards Models; Retrospective Studies; Tomography, X-Ray Computed; Ultrasonography

2012
What is a safe future liver remnant size in patients undergoing major hepatectomy for colorectal liver metastases and treated by intensive preoperative chemotherapy?
    Annals of surgical oncology, 2012, Volume: 19, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Female; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Postoperative Complications; Preoperative Care; Prognosis; Survival Rate

2012
Liver injury due to chemotherapy-induced sinusoidal obstruction syndrome is associated with sinusoidal capillarization.
    Annals of surgical oncology, 2012, Volume: 19, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Chemical and Drug Induced Liver Injury; Colorectal Neoplasms; Combined Modality Therapy; Female; Follow-Up Studies; Hepatectomy; Hepatic Veno-Occlusive Disease; Humans; Indocyanine Green; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Organoplatinum Compounds; Oxaliplatin; Prognosis; Risk Factors; Survival Rate

2012
Pathologic response to preoperative chemotherapy in colorectal liver metastases: fibrosis, not necrosis, predicts outcome.
    Annals of surgical oncology, 2012, Volume: 19, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Fibrosis; Hepatectomy; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Mucins; Multivariate Analysis; Necrosis; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Prognosis; Retrospective Studies; Single-Blind Method

2012
[Successful management of liver metastasis from gastric adenosquamous carcinoma with adjuvant chemotherapy and radiofrequency ablation].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2012, Volume: 109, Issue:4

    Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Adenosquamous; Catheter Ablation; Cisplatin; Combined Modality Therapy; Humans; Irinotecan; Liver Neoplasms; Male; Stomach Neoplasms

2012
Detailed liver-specific imaging prior to pre-operative chemotherapy for colorectal liver metastases reduces intra-hepatic recurrence and the need for a repeat hepatectomy.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2012, Volume: 14, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; England; Female; Hepatectomy; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Predictive Value of Tests; Proportional Hazards Models; Reoperation; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome

2012
[A case of remnant liver metastases after resection of liver metastases from rectal cancer following treatment with 5-FU, L-OHP and CPT-11, with markedly effective treatment by cetuximab plus S-1].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:5

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Combined Modality Therapy; Drug Combinations; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Male; Mutation; Organoplatinum Compounds; Oxaliplatin; Oxonic Acid; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Rectal Neoplasms; Recurrence; Salvage Therapy; Tegafur; Tomography, X-Ray Computed

2012
Progression while receiving preoperative chemotherapy should not be an absolute contraindication to liver resection for colorectal metastases.
    Annals of surgical oncology, 2012, Volume: 19, Issue:9

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Carcinoembryonic Antigen; Cetuximab; Colorectal Neoplasms; Contraindications; Disease Progression; Disease-Free Survival; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Kaplan-Meier Estimate; Liver Neoplasms; Male; Multivariate Analysis; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Proportional Hazards Models; Retrospective Studies; Risk Factors; Survival Rate; Tumor Burden

2012
Combined portal vein embolization and preoperative chemotherapy prior to liver resection for colorectal cancer metastases.
    Scandinavian journal of gastroenterology, 2012, Volume: 47, Issue:8-9

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Blood Loss, Surgical; Blood Volume; Camptothecin; Carcinoma; Cetuximab; Chemotherapy, Adjuvant; Colorectal Neoplasms; Embolization, Therapeutic; Female; Hepatectomy; Humans; Irinotecan; Kaplan-Meier Estimate; Length of Stay; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Operative Time; Organoplatinum Compounds; Oxaliplatin; Portal Vein; Retrospective Studies; Statistics, Nonparametric

2012
Comparing time to disease progression of irinotecan and oxaliplatin-based chemotherapies in colorectal cancer patients with liver only metastasis.
    American journal of clinical oncology, 2013, Volume: 36, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cohort Studies; Colorectal Neoplasms; Databases, Factual; Disease Progression; Disease-Free Survival; Female; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies; Risk Assessment; Survival Analysis; Time Factors; Treatment Outcome

2013
Bradycardia associated with drug-eluting beads loaded with irinotecan (DEBIRI) infusion for colorectal liver metastases.
    Cardiovascular and interventional radiology, 2013, Volume: 36, Issue:3

    Topics: Aged; Antineoplastic Agents, Phytogenic; Bradycardia; Camptothecin; Colorectal Neoplasms; Cone-Beam Computed Tomography; Drug Delivery Systems; Electrocardiography; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged

2013
First human study in treatment of unresectable liver metastases from colorectal cancer with irinotecan-loaded beads (DEBIRI).
    International journal of oncology, 2012, Volume: 41, Issue:4

    Topics: Aged; Aged, 80 and over; Camptothecin; Chemoembolization, Therapeutic; Colorectal Neoplasms; Drug Delivery Systems; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Treatment Outcome

2012
[A case of poorly-differentiated neuroendocrine carcinoma of the ascending colon with multiple liver metastases successfully treated with cisplatin and irinotecan].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Neuroendocrine; Cell Differentiation; Cisplatin; Colon, Ascending; Fatal Outcome; Female; Humans; Irinotecan; Liver Neoplasms; Tomography, X-Ray Computed

2012
Perioperative chemotherapy with or without bevacizumab in patients with metastatic colorectal cancer undergoing liver resection.
    Clinical colorectal cancer, 2013, Volume: 12, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Colorectal Neoplasms; Combined Modality Therapy; Deoxycytidine; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Perioperative Care; Postoperative Complications; Prognosis; Retrospective Studies; Survival Rate

2013
Bevacizumab plus chemotherapy in metastatic colorectal cancer patients treated in clinical practice.
    Future oncology (London, England), 2012, Volume: 8, Issue:9

    Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; DNA Mutational Analysis; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Retrospective Studies; Survival Analysis; Treatment Outcome

2012
Preoperative chemotherapy and the risk of hepatotoxicity and morbidity after liver resection for metastatic colorectal cancer: a single institution experience.
    Journal of the American College of Surgeons, 2013, Volume: 216, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemical and Drug Induced Liver Injury; Chemotherapy, Adjuvant; Cohort Studies; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Postoperative Complications; Retrospective Studies; Risk Factors; Treatment Outcome

2013
BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistance in vitro and in vivo.
    Molecular pharmaceutics, 2012, Nov-05, Volume: 9, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Breast Neoplasms; Calcium Channel Blockers; Camptothecin; Carcinoma, Hepatocellular; Cell Proliferation; Cells, Cultured; Cisplatin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Fluorescent Antibody Technique; Humans; In Vitro Techniques; Irinotecan; KB Cells; Liver Neoplasms; Male; Mice; Mice, Nude; Models, Molecular; Molecular Docking Simulation; Paclitaxel; Piperidines; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triterpenes; Verapamil

2012
Impact of STAT3 phosphorylation on the clinical effectiveness of anti-EGFR-based therapy in patients with metastatic colorectal cancer.
    Clinical colorectal cancer, 2013, Volume: 12, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colorectal Neoplasms; ErbB Receptors; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Irinotecan; Liver Neoplasms; Male; Middle Aged; Mutation; Organoplatinum Compounds; Oxaliplatin; Phosphorylation; Prognosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Retrospective Studies; Signal Transduction; STAT3 Transcription Factor; Survival Rate

2013
A survival analysis of the liver-first reversed management of advanced simultaneous colorectal liver metastases: a LiverMetSurvey-based study.
    Annals of surgery, 2012, Volume: 256, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chi-Square Distribution; Colorectal Neoplasms; Combined Modality Therapy; Female; Humans; Irinotecan; Liver Neoplasms; Logistic Models; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Propensity Score; Proportional Hazards Models; Registries; Retrospective Studies; Survival Analysis; Treatment Outcome

2012
Optimal morphologic response to preoperative chemotherapy: an alternate outcome end point before resection of hepatic colorectal metastases.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Dec-20, Volume: 30, Issue:36

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; Cohort Studies; Colorectal Neoplasms; Female; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome

2012
Hepatic arterial infusion of irinotecan, 5-Fluorouracil and leucovorin in patients with liver metastases from colorectal carcinoma.
    Anticancer research, 2012, Volume: 32, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Retrospective Studies; Survival Rate

2012
Adjuvant chemotherapy after resection of colorectal liver metastases in patients at high risk of hepatic recurrence: a comparative study between hepatic arterial infusion of oxaliplatin and modern systemic chemotherapy.
    Annals of surgery, 2013, Volume: 257, Issue:1

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Studies; Hepatectomy; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies; Survival Analysis; Treatment Outcome

2013
Validation study of a prognostic classification in patients with metastatic colorectal cancer who received irinotecan-based second-line chemotherapy.
    Journal of cancer research and clinical oncology, 2013, Volume: 139, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cohort Studies; Colorectal Neoplasms; Female; Fluorouracil; Follow-Up Studies; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Peritoneal Neoplasms; Prognosis; Survival Rate

2013
Irinotecan during pregnancy in metastatic colon cancer.
    Tumori, 2012, Volume: 98, Issue:6

    Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cesarean Section; Colectomy; Colonic Neoplasms; Disease Progression; Female; Fluorouracil; Gestational Age; Humans; Infant, Newborn; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Treatment Failure

2012
[CPT-11 hepatic arterial injection plus oral UFT administration for liver metastasis of rectal cancer--report of two cases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:8

    Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Drug Combinations; Hepatic Artery; Humans; Injections, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Rectal Neoplasms; Tegafur; Uracil

2002
Irinotecan, cisplatin and mitomycin in inoperable gastro-oesophageal and pancreatic cancers - a new active regimen.
    British journal of cancer, 2002, Oct-07, Volume: 87, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Squamous Cell; Cisplatin; Disease Progression; Esophageal Neoplasms; Female; Gastrointestinal Diseases; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Mitomycin; Neutropenia; Pancreatic Neoplasms; Stomach Neoplasms; Treatment Outcome

2002
Augmented anti-metastatic efficacy of a selective matrix metalloproteinase inhibitor, MMI-166, in combination with CPT-11.
    Clinical & experimental metastasis, 2002, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Agents; Camptothecin; Colonic Neoplasms; Disease Models, Animal; Humans; Irinotecan; Liver Neoplasms; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Sulfonamides; Transplantation, Heterologous

2002
Novel therapeutic approaches in the treatment of children with hepatoblastoma.
    Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Child; Child, Preschool; Hepatoblastoma; Humans; Irinotecan; Liver Neoplasms; Neoplasm Recurrence, Local

2002
[A case of postoperative liver metastasis of alpha-fetoprotein producing gastric cancer successfully treated with intrahepatic chemotherapy (adriamycin, cisplatin, irinotecan hydrochloride)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:12

    Topics: alpha-Fetoproteins; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Doxorubicin; Gastrectomy; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Stomach Neoplasms

2002
[Hepatic arterial infusion with irinotecan for the colorectal cancer patient with liver metastasis--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Female; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Middle Aged; Rectal Neoplasms

2002
[A case of gastric cancer associated with synchronous liver metastasis successfully treated with combination therapy of systemic and hepatic arterial infusion chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:12

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Methotrexate; Middle Aged; Stomach Neoplasms

2002
Irinotecan plus low-dose cisplatin for alpha-fetoprotein-producing gastric carcinoma with multiple liver metastases: report of two cases.
    Surgery today, 2002, Volume: 32, Issue:12

    Topics: Aged; alpha-Fetoproteins; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Male; Middle Aged; Stomach Neoplasms; Tomography, X-Ray Computed

2002
Safety and efficacy of outpatient treatment with CPT-11 plus bolus folinic acid/5-fluorouracil as first-line chemotherapy for metastatic colorectal cancer.
    Anti-cancer drugs, 2003, Volume: 14, Issue:1

    Topics: Adult; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Survival Rate

2003
Hepatic artery infusion for liver metastases from colorectal cancer.
    Lancet (London, England), 2003, Feb-01, Volume: 361, Issue:9355

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Survival Analysis; Treatment Outcome

2003
[A case of metastatic liver tumor of colorectal cancer responding to low-dose CPT-11 chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged

2003
Weekly hepatic arterial infusion of 5-fluorouracil and subsequent systemic chemotherapy for liver metastases from colorectal cancer.
    Japanese journal of clinical oncology, 2003, Volume: 33, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Colonic Neoplasms; Drug Administration Schedule; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leukopenia; Liver Neoplasms; Male; Middle Aged; Nausea; Rectal Neoplasms; Retrospective Studies; Survival Analysis; Thrombocytopenia; Vomiting, Anticipatory

2003
[A case of irinotecan-resistant colon cancer responding to chronotherapy with oxaliplatin, 5-FU, l-LV].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Chronotherapy; Colonic Neoplasms; Drug Evaluation; Drug Resistance, Neoplasm; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Organoplatinum Compounds; Oxaliplatin

2003
Dramatic response of multiply relapsed hepatoblastoma to irinotecan (CPT-11).
    Medical and pediatric oncology, 2003, Volume: 41, Issue:1

    Topics: Adolescent; alpha-Fetoproteins; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Administration Schedule; Hepatoblastoma; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Multiple Primary

2003
[A case of colon cancer with liver metastases and lymph node metastases successfully treated with surgery followed by CPT-11 and 5-FU chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Aorta, Abdominal; Camptothecin; Colonic Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Gastrectomy; Humans; Irinotecan; Liver Neoplasms; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Middle Aged

2003
Phlebitis due to irinotecan.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2003, Volume: 15, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Arm; Camptothecin; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Male; Middle Aged; Phlebitis; Rectal Neoplasms

2003
Is liver disease an octreotide side effect?
    Journal of clinical gastroenterology, 2003, Volume: 37, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Hepatocellular; Drug Administration Schedule; Female; Fluorouracil; Gastrointestinal Agents; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Octreotide

2003
[A case of gastric cancer with multiple liver metastasis responding to combination therapy of CPT-11 and CDDP].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Administration Schedule; Gastrectomy; Humans; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Stomach Neoplasms

2003
Epidermal growth factor receptor inhibition induces trichomegaly.
    Acta oncologica (Stockholm, Sweden), 2003, Volume: 42, Issue:4

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colonic Neoplasms; Diagnosis, Differential; ErbB Receptors; Eyelashes; Female; Humans; Irinotecan; Liver Neoplasms; Neoplasm Metastasis

2003
[A case of effective weekly paclitaxel administration for metastatic gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Resistance, Neoplasm; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Paclitaxel; Stomach Neoplasms

2003
[Experimental study on intraperitoneal versus intravenous CPT-11 for peritoneal seeding and liver metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Colonic Neoplasms; Female; Infusions, Intravenous; Injections, Intraperitoneal; Irinotecan; Liver Neoplasms; Mice; Mice, Inbred BALB C; Peritoneal Neoplasms

2003
[A case of resected spinal metastasis following colectomy and hepatectomy for descending colon carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Spinal Neoplasms

2003
[A case of hepatic metastasis and local recurrence from rectal cancer responding to hepatic arterial infusion and systemic chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Drug Combinations; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Rectal Neoplasms; Tegafur; Uracil

2003
[A case of unresectable liver metastases from rectosigmoid colon cancer with survival for over 3 years after multidisciplinary treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Mitomycin; Rectal Neoplasms; Sigmoid Neoplasms

2003
[A case of spinal infarction related to hepatic arterial infusion chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Cecal Neoplasms; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Infarction; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Spine

2003
[A case of advanced cancer with liver metastasis and paraaortic lymph node metastasis responding remarkably to combination chemotherapy of low-dose CDDP, 5-FU and CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta; Camptothecin; Cisplatin; Drug Administration Schedule; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Stomach Neoplasms

2003
Perioperative complications in patients undergoing major liver resection with or without neoadjuvant chemotherapy.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2003, Volume: 7, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Colonic Neoplasms; Female; Fluorouracil; Folic Acid; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Postoperative Complications; Retrospective Studies

2003
[A case of isolated hepatic malignant lymphoma representing characteristic findings on radiological imaging].
    Fukuoka igaku zasshi = Hukuoka acta medica, 2003, Volume: 94, Issue:11

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Irinotecan; L-Lactate Dehydrogenase; Liver Neoplasms; Lymphoma; Magnetic Resonance Imaging; Male; Neoplasm Recurrence, Local; Prednisolone; Tomography, X-Ray Computed; Treatment Outcome; Vincristine

2003
First-line hepatic infusion of pirarubicin in patients with isolated liver metastases: is it really promising?
    Annals of oncology : official journal of the European Society for Medical Oncology, 2004, Volume: 15, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Clinical Trials as Topic; Colorectal Neoplasms; Doxorubicin; Fluorouracil; Health Care Costs; Hepatic Artery; Humans; Immunosuppressive Agents; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Patient Selection; Treatment Outcome

2004
ABCG2 overexpression in colon cancer cells resistant to SN38 and in irinotecan-treated metastases.
    International journal of cancer, 2004, May-10, Volume: 109, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Colon; Colonic Neoplasms; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Liver Neoplasms; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm

2004
[Two cases of metastatic or recurrent rectal cancer responding to combined chemotherapy of low-dose CPT-11 and 5'-DFUR as second-line chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Dose-Response Relationship, Drug; Drug Administration Schedule; Floxuridine; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Male; Middle Aged; Quality of Life; Rectal Neoplasms

2004
[A case report of colon cancer with liver and lung metastases responding to combination chemotherapy with l-LV, 5-fluorouracil and CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Administration Schedule; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Tumor Cells, Cultured

2004
[A case of highly advanced ascending colon cancer with multiple bone and liver metastases and pleuritis carcinomatosa treated with pharmacokinetic modulating chemotherapy and low-dose CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Pleurisy; Quality of Life; Tegafur; Uracil

2004
[A case of colon carcinoma with unresectable multiple liver metastases responding to various combined chemotherapies centering on hepatic arterial infusion therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:5

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Quality of Life

2004
[Retrospective study of irinotecan plus fluorouracil and l-leucovorin chemotherapy for advanced and metastatic colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Leukopenia; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Retrospective Studies; Treatment Outcome

2004
[Resection of liver metastasis of colorectal origin following chemotherapy with irinotecan].
    Annales de chirurgie, 2004, Volume: 129 Spec No 2

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Survival Rate

2004
Activity of irinotecan, cisplatin and dacarbazine (CPD) combination in previously treated patients with advanced colorectal carcinoma.
    Experimental oncology, 2004, Volume: 26, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Cisplatin; Colorectal Neoplasms; Dacarbazine; Disease-Free Survival; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Survival Rate; Treatment Outcome

2004
Extent of hepatic resection does not correlate with toxicity following adjuvant chemotherapy.
    Journal of surgical oncology, 2004, Aug-01, Volume: 87, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Diarrhea; Drug Administration Schedule; Female; Fluorouracil; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Leukopenia; Liver; Liver Neoplasms; Male; Middle Aged; Neutropenia; Retrospective Studies

2004
Treatment issues in pediatric gastric adenocarcinoma.
    Journal of pediatric surgery, 2004, Volume: 39, Issue:8

    Topics: Anastomosis, Roux-en-Y; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Signet Ring Cell; Catheter Ablation; Chemotherapy, Adjuvant; Child; Cisplatin; Combined Modality Therapy; Docetaxel; Female; Fluorouracil; Gastrectomy; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Irinotecan; Liver Neoplasms; Lymph Node Excision; Neoplasm Recurrence, Local; Neoplastic Syndromes, Hereditary; Pancreatectomy; Prognosis; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Remission Induction; Reoperation; Splenectomy; Stomach Neoplasms; Taxoids

2004
[A case of hepatic metastasis from colon cancer successfully treated with 5-FU, levofolinate (l-LV) and low-dose CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colectomy; Colonic Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Remission Induction

2004
[A successfully resected case of colorectal cancer with multiple liver metastases treated with systemic chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:8

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colon, Sigmoid; Combined Modality Therapy; Drug Administration Schedule; Electrocoagulation; Fluorouracil; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Microwaves; Middle Aged; Sigmoid Neoplasms; Survivors

2004
Development of a chemoresistant orthotopic human nonsmall cell lung carcinoma model in nude mice: analyses of tumor heterogenity in relation to the immunohistochemical levels of expression of cyclooxygenase-2, ornithine decarboxylase, lung-related resista
    Cancer, 2004, Oct-15, Volume: 101, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Brain Neoplasms; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cyclooxygenase 2; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Intramolecular Oxidoreductases; Irinotecan; Isoenzymes; Liver Neoplasms; Lung Neoplasms; Membrane Proteins; Mice; Mice, Nude; Neoplasm Proteins; Organoplatinum Compounds; Ornithine Decarboxylase; Oxaliplatin; Paclitaxel; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Survival Rate; Transplantation, Heterologous; Vault Ribonucleoprotein Particles

2004
[A case of metastatic liver tumor from colorectal carcinoma--continued arterial infusion chemotherapy through a microcatheter located in replaced right hepatic artery].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Catheters, Indwelling; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male

2004
Liposomal irinotecan: formulation development and therapeutic assessment in murine xenograft models of colorectal cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Oct-01, Volume: 10, Issue:19

    Topics: Animals; Camptothecin; Capsules; Cell Line, Tumor; Colorectal Neoplasms; Dose-Response Relationship, Drug; Humans; Injections, Intravenous; Irinotecan; Liposomes; Liver Neoplasms; Male; Mice; Mice, SCID; Survival Analysis; Time Factors; Treatment Outcome; Xenograft Model Antitumor Assays

2004
[Successful treatment of liver metastasis and extrahepatic metastasis with hepatic arterial infusion of CDDP, CPT-11, and 5-FU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colonic Neoplasms; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Rectal Neoplasms

2004
[Case report--Complete response of liver metastasis of rectal cancer after combination chemotherapy of CPT-11 + UFT-E].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Rectal Neoplasms; Tegafur; Uracil

2004
[CPT-11 hepatic arterial infusion chemotherapy for metastatic liver tumor from gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11

    Topics: Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Stomach Neoplasms

2004
Tumor progression while on chemotherapy: a contraindication to liver resection for multiple colorectal metastases?
    Annals of surgery, 2004, Volume: 240, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Contraindications; Enzyme Inhibitors; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies; Topoisomerase I Inhibitors

2004
[A case of liver metastatic recurrence of gastric cancer effectively treated by combined chemotherapy of CPT-11 and CDDP].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Female; Gastrectomy; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Quality of Life; Stomach Neoplasms

2004
Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL.
    Cancer research, 2004, Dec-15, Volume: 64, Issue:24

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Camptothecin; Colonic Neoplasms; Drug Synergism; Female; HCT116 Cells; Humans; Irinotecan; Janus Kinase 2; Liver Neoplasms; Membrane Glycoproteins; Mice; Mice, Nude; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; TNF-Related Apoptosis-Inducing Ligand; Topoisomerase I Inhibitors; Transfection; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; X-Linked Inhibitor of Apoptosis Protein; Xenograft Model Antitumor Assays

2004
Limited potential of hepatic arterial infusion of irinotecan.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16 Suppl 5

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms

2004
Effects of nonselective cyclooxygenase inhibition with low-dose ibuprofen on tumor growth, angiogenesis, metastasis, and survival in a mouse model of colorectal cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Feb-15, Volume: 11, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Camptothecin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Fluorouracil; HT29 Cells; Humans; Ibuprofen; Irinotecan; Lactones; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Prostaglandin-Endoperoxide Synthases; Sulfones; Survival Analysis; Xenograft Model Antitumor Assays

2005
The histone-deacetylase inhibitor SAHA potentiates proapoptotic effects of 5-fluorouracil and irinotecan in hepatoma cells.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Caspases; Down-Regulation; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Fluorouracil; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Irinotecan; Liver Neoplasms; Membrane Potentials; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Skin; Tumor Cells, Cultured; Vorinostat

2005
Is there a new drug beyond floxuridine for intra-arterial hepatic chemotherapy in liver metastases from colorectal cancer?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Mar-20, Volume: 23, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dexamethasone; Floxuridine; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms

2005
Blocking of PI3K/Akt pathway enhances apoptosis induced by SN-38, an active form of CPT-11, in human hepatoma cells.
    International journal of oncology, 2005, Volume: 26, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Carcinoma, Hepatocellular; Drug Resistance, Neoplasm; Humans; Irinotecan; Liver Neoplasms; NF-kappa B; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tumor Cells, Cultured

2005
Isolated hepatic perfusion for the treatment of patients with colorectal cancer liver metastases after irinotecan-based therapy.
    Annals of surgical oncology, 2005, Volume: 12, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Camptothecin; Chemotherapy, Cancer, Regional Perfusion; Colorectal Neoplasms; Disease Progression; Female; Humans; Hyperthermia, Induced; Irinotecan; Liver Neoplasms; Male; Melphalan; Middle Aged; Neoplasm Staging; Treatment Failure; Treatment Outcome

2005
Drg1 expression in 131 colorectal liver metastases: correlation with clinical variables and patient outcomes.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, May-01, Volume: 11, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Cycle Proteins; Colorectal Neoplasms; Female; Fluorouracil; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Irinotecan; Liver Neoplasms; Male; Middle Aged; Prognosis; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome

2005
Combined systemic chronotherapy and hepatic artery infusion for the treatment of metastatic colorectal cancer confined to the liver.
    Chemotherapy, 2005, Volume: 51, Issue:2-3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Chronotherapy; Colorectal Neoplasms; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Quality of Life

2005
[Systemic therapy for colorectal cancer].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2005, Volume: 76, Issue:6

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Cetuximab; Colorectal Neoplasms; Drug Synergism; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Prodrugs; Randomized Controlled Trials as Topic; Treatment Outcome

2005
Effect of steatohepatitis associated with irinotecan or oxaliplatin pretreatment on resectability of hepatic colorectal metastases.
    Journal of the American College of Surgeons, 2005, Volume: 200, Issue:6

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Fatty Liver; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Prospective Studies; Risk Factors; Topoisomerase I Inhibitors

2005
A mouse model for developing treatment for secondary liver tumors.
    International journal of oncology, 2005, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Humans; Immunohistochemistry; Irinotecan; Liver; Liver Neoplasms; Magnetic Resonance Imaging; Male; Mice; Mice, Nude; Neoplasm Metastasis; Time Factors

2005
Synthesis and antitumor activity of A-ring modified hexacyclic analogues of camptothecin.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:3

    Topics: Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Female; Humans; Irinotecan; Liver Neoplasms; Mice; Neoplasm Transplantation; Polycyclic Compounds

2005
[Follicular drug reaction from cetuximab: a common side effect in the treatment of metastatic colon carcinoma].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2006, Volume: 57, Issue:8

    Topics: Anaphylaxis; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colonic Neoplasms; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Eruptions; Folliculitis; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Male; Middle Aged; Skin

2006
[New oncolytic agents and immunomodulators and their application].
    Nederlands tijdschrift voor geneeskunde, 2005, Jun-25, Volume: 149, Issue:26

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Camptothecin; Colorectal Neoplasms; Drug Therapy, Combination; Humans; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Survival Analysis; Treatment Outcome

2005
Pharmacokinetic changes of irinotecan by intestinal alkalinization in an advanced colorectal cancer patient.
    Therapeutic drug monitoring, 2005, Volume: 27, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Area Under Curve; Camptothecin; Colorectal Neoplasms; Diarrhea; Humans; Hydrogen-Ion Concentration; Intestines; Irinotecan; Liver Neoplasms; Male; Middle Aged

2005
[Second-line chemotherapy with bi-weekly CPT-11 and cisplatin for recurrent colorectal cancer resistant to 5-FU based chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:7

    Topics: Adult; Aged; Alopecia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colonic Neoplasms; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Nausea; Neoplasm Recurrence, Local; Rectal Neoplasms

2005
[Combination chemotherapy with oral TS-1 and low-dose CPT-11 by hepatic arterial infusion for multiple hepatic metastases from colon cancer--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:7

    Topics: Adenocarcinoma; Administration, Oral; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Oxonic Acid; Pyridines; Tegafur

2005
[Application of adenosine triphosphate tumor chemosensitive assay system to individual chemotherapy for hepatocellular carcinoma].
    Ai zheng = Aizheng = Chinese journal of cancer, 2005, Volume: 24, Issue:8

    Topics: Adenosine Triphosphate; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Deoxycytidine; Disease-Free Survival; Drug Screening Assays, Antitumor; Female; Gemcitabine; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Paclitaxel; Postoperative Period; Remission Induction; Sensitivity and Specificity; Survival Rate

2005
Regression of colorectal adenomas with intravenous cytotoxic chemotherapy in a patient with familial adenomatous polyposis.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Sep-01, Volume: 23, Issue:25

    Topics: Adenoma; Adenomatous Polyposis Coli; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Middle Aged; Treatment Outcome

2005
Good tolerance of weekly irinotecan in a patient with metastatic colorectal cancer on chronic hemodialysis.
    Journal of chemotherapy (Florence, Italy), 2005, Volume: 17, Issue:4

    Topics: Adenocarcinoma; Camptothecin; Colorectal Neoplasms; Diabetic Nephropathies; Drug Administration Schedule; Follow-Up Studies; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Renal Dialysis; Risk Assessment; Treatment Outcome

2005
[A case of colon cancer with liver and lung metastases-efficacy of CPT-11/5-FU/l-LV (IFL) as part of ambulatory treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:9

    Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colectomy; Drug Administration Schedule; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymph Node Excision; Male; Middle Aged; Quality of Life; Sigmoid Neoplasms

2005
[A case of advanced gastric cancer with obstructive jaundice that responded to TS-1/CPT-11 combination therapy after percutaneous transhepatic cholangio drainage].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biliary Tract; Camptothecin; Combined Modality Therapy; Drainage; Drug Administration Schedule; Drug Combinations; Gastroscopy; Humans; Irinotecan; Jaundice, Obstructive; Liver Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Oxonic Acid; Pyridines; Stomach Neoplasms; Tegafur

2005
[A case of small cell carcinoma of the stomach].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Gastrectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Invasiveness; Pancreatic Neoplasms; Rupture, Spontaneous; Stomach Neoplasms; Stomach Rupture

2005
[A case of colon cancer with multiple liver, lung and bone metastases successfully treated with combined weekly high-dose 5-FU (WHF) chemotherapy with UFT and CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Fluorouracil; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Lung Neoplasms; Middle Aged; Tegafur; Uracil

2005
[A case of cecal cancer with multiple liver metastases responding to irinotecan (CPT-11)/cisplatin (CDDP) combination therapy for elevation of CA19-9 after complete response (CR) by l-leucovorin(LV)/5-fluorouracil(5-FU) therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Camptothecin; Cecal Neoplasms; Cisplatin; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps, Implantable; Irinotecan; Leucovorin; Liver Neoplasms; Middle Aged

2005
[Chemotherapy for liver metastasis of colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:11

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged

2005
[A case of metastatic colon cancer treated with oxaliplatin combination chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:11

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Floxuridine; Humans; Irinotecan; Liver Neoplasms; Male; Organoplatinum Compounds; Oxaliplatin; Quality of Life

2005
[A case report of recurrence of liver metastases from colorectal cancer, which seemed to have vanished for a time by intra-aortic chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:11

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Fluorouracil; Hepatectomy; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Neoplasm Recurrence, Local

2005
Novel two-step resection for lesions between the middle hepatic vein and vena cava which allows the middle hepatic vein to be preserved.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Chemotherapy, Adjuvant; Colonic Neoplasms; Fluorouracil; Follow-Up Studies; Hepatectomy; Hepatic Veins; Humans; Irinotecan; Leucovorin; Liver; Liver Neoplasms; Liver Regeneration; Male; Rectal Neoplasms; Vena Cava, Inferior

2006
Unresectable hepatic colorectal metastases: need for new surgical strategies.
    Annals of surgical oncology, 2006, Volume: 13, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin; Treatment Outcome

2006
[A case report of poorly-differentiated adenocarcinoma in sigmoid colon cancer with liver and pulmonary metastasis responding to TS-1 and CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:1

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Drug Combinations; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Oxonic Acid; Pyridines; Sigmoid Neoplasms; Tegafur; Tomography, X-Ray Computed

2006
PET/CT in the evaluation of response to treatment of liver metastases from colorectal cancer with bevacizumab and irinotecan.
    Technology in cancer research & treatment, 2006, Volume: 5, Issue:1

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Female; Fluorodeoxyglucose F18; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, X-Ray Computed; Treatment Outcome

2006
Central nervous system toxicity induced by irinotecan.
    Journal of the National Cancer Institute, 2006, Feb-01, Volume: 98, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Central Nervous System; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Male; Middle Aged; Sigmoid Neoplasms; Tachyphylaxis

2006
Transarterial chemoembolization with degradable starch microspheres, irinotecan, and mitomycin-C in patients with liver metastases.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoembolization, Therapeutic; Colonic Neoplasms; Disease Progression; Hepatic Artery; Humans; Injections, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Microspheres; Middle Aged; Mitomycin; Rectal Neoplasms; Remission Induction; Starch; Stomach Neoplasms; Topoisomerase I Inhibitors

2006
A case of esophageal small cell carcinoma with multiple liver metastases responding to chemotherapy with irinotecan plus cisplatin.
    Journal of experimental & clinical cancer research : CR, 2005, Volume: 24, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Esophageal Neoplasms; Humans; Irinotecan; Liver Neoplasms; Male; Tomography, X-Ray Computed

2005
[The results of cetuximab treatment of a patient with multiple pretreated, irinotecan resistant metastatic colorectal cancer].
    Magyar onkologia, 2005, Volume: 49, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma; Cetuximab; Colorectal Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Signal Transduction; Tomography, X-Ray Computed; Treatment Outcome

2005
[A case of gastric cancer with multiple liver metastases resistant to TS-1 responding to chemotherapy with paclitaxel plus doxifluridine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:4

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Drug Combinations; Drug Resistance, Neoplasm; Floxuridine; Humans; Irinotecan; Liver Neoplasms; Male; Oxonic Acid; Paclitaxel; Pyridines; Stomach Neoplasms; Tegafur

2006
Postchemotherapy characteristics of hepatic colorectal metastases: remnants of uncertain malignant potential.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Colonic Neoplasms; DNA Repair; Follow-Up Studies; Gene Silencing; Hepatectomy; Humans; Irinotecan; Liver; Liver Neoplasms; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; O(6)-Methylguanine-DNA Methyltransferase; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Rectal Neoplasms; Remission Induction; Retrospective Studies; Topoisomerase I Inhibitors

2006
[A patient with hepatic, pulmonary, and nodal metastases of colon cancer responding to CPT-11/TS-1 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Oxonic Acid; Pyridines; Quality of Life; Tegafur

2006
[Advanced rectal cancer in an older patient, in whom metastatic liver lesions were effectively controlled with oral UFT+LV and venous CPT-11 administration--case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:6

    Topics: Adenocarcinoma; Administration, Oral; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colon, Sigmoid; Colostomy; Drug Administration Schedule; Drug Combinations; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Omentum; Peritoneal Neoplasms; Rectal Neoplasms; Remission Induction; Tegafur; Uracil

2006
Response of heavily treated and relapsed hepatoblastoma in the transplanted liver to single-agent therapy with irinotecan.
    Pediatric transplantation, 2006, Volume: 10, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Child; Hepatoblastoma; Humans; Irinotecan; Liver Neoplasms; Liver Transplantation; Living Donors; Male; Neoplasm Recurrence, Local

2006
Potential application of GSTT1-null genotype in predicting toxicity associated to 5-fluouracil irinotecan and leucovorin regimen in advanced stage colorectal cancer patients.
    Oncology reports, 2006, Volume: 16, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Genotype; Glutathione Transferase; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length

2006
Irinotecan combined with infusional 5-fluorouracil and high-dose leucovorin for the treatment of advanced gastric carcinoma as the first-line chemotherapy.
    Chemotherapy, 2006, Volume: 52, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Disease-Free Survival; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Peritoneal Neoplasms; Stomach Neoplasms; Survival Rate

2006
[Multiple hepatic metastases of colon cancer responding to combined therapy with TS-1 and CPT-11--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Administration Schedule; Drug Combinations; Female; Humans; Irinotecan; Liver Neoplasms; Oxonic Acid; Remission Induction; Tegafur

2006
Chemotherapy and regional therapy of hepatic colorectal metastases: expert consensus statement by Bartlett et al.
    Annals of surgical oncology, 2006, Volume: 13, Issue:10

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin

2006
Chemotherapy and regional therapy of hepatic colorectal metastases: expert consensus statement.
    Annals of surgical oncology, 2006, Volume: 13, Issue:10

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Hepatectomy; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Organoplatinum Compounds; Oxaliplatin

2006
[Evaluation of weekly low-dose CPT-11 combined with 5-FU/l-LV therapy for advanced and recurrent colorectal cancer--preliminary study].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:9

    Topics: Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Leukopenia; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Quality of Life; Rectal Neoplasms

2006
[A case of advanced gastric cancer with liver metastasis completely responding to CPT-11+low-dose 5-FU+CDDP chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:9

    Topics: Adenocarcinoma; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cardia; Cisplatin; Drug Administration Schedule; Drug Combinations; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Oxonic Acid; Remission Induction; Stomach Neoplasms; Tegafur

2006
[A case of non-curatively resected colon cancer with liver and lymph node metastases treated by TS-1/CPT-11 combination therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoembryonic Antigen; Colectomy; Colonic Neoplasms; Drug Administration Schedule; Drug Combinations; Humans; Irinotecan; Liver Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Oxonic Acid; Tegafur

2006
Hepatic transport, metabolism and biliary excretion of irinotecan in a cancer patient with an external bile drain.
    Cancer biology & therapy, 2006, Volume: 5, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Phytogenic; Bile Ducts; Biliary Tract; Camptothecin; Drainage; Feces; Humans; Irinotecan; Liver; Liver Neoplasms; Male; Pancreatic Neoplasms; Prodrugs

2006
[A case of advanced gastric cancer with long-term survival treated by chemotherapy and surgical cytoreduction].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:10

    Topics: Adenocarcinoma, Mucinous; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Gastrectomy; Humans; Irinotecan; Liver Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Oxonic Acid; Quality of Life; Stomach Neoplasms; Survivors; Tegafur

2006
[Case report of a liver metastasis from rectal cancer achieving complete response (CR) by a combination of intra-hepatic arterial infusion of irinotecan (CPT-11) with degradable starch microspheres (DSM) and weekly high-dose intra-hepatic arterial chemoth
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:10

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Mitomycin; Rectal Neoplasms; Starch

2006
Importance of histological tumor response assessment in predicting the outcome in patients with colorectal liver metastases treated with neo-adjuvant chemotherapy followed by liver surgery.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Combined Modality Therapy; Disease-Free Survival; Female; Fibrosis; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Survival Rate; Treatment Outcome

2007
Chemotherapy for colorectal cancer prior to liver resection for colorectal cancer hepatic metastases does not adversely affect peri-operative outcomes.
    Journal of surgical oncology, 2007, Jan-01, Volume: 95, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Cohort Studies; Colorectal Neoplasms; Drug Administration Schedule; Fatty Liver; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Preoperative Care; Retrospective Studies; Treatment Outcome

2007
[A recurrent endocrine cell cancer of the stomach showing almost complete remission after chemotherapy for 1 year].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:13

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Camptothecin; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Gastrectomy; Humans; Irinotecan; Liver Neoplasms; Male; Remission Induction; Stomach Neoplasms

2006
A case report--The marked response to gemcitabine combined with irinotecan and low-dose cisplatin chemotherapy for advanced gastric cancer with multiple liver metastases.
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; Irinotecan; Liver Neoplasms; Male; Remission Induction; Stomach Neoplasms; Treatment Outcome

2006
[A case of successfully treated unresectable multiple liver metastases from colon cancer by hepatic arterial infusion chemotherapy and systemic chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:12

    Topics: Aged; Camptothecin; Carcinoma; Colectomy; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Remission Induction; Sigmoid Neoplasms

2006
[Successful CPT-11 treatment in a patient with pancreatic cancer associated with multiple liver metastases and chronic renal failure].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Administration Schedule; Female; Humans; Irinotecan; Kidney Failure, Chronic; Liver Neoplasms; Middle Aged; Pancreatic Neoplasms; Remission Induction

2007
[CR of rectal cancer and synchronous liver and lung metastases obtained with TS-1 plus CPT-11 combination therapy--case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:1

    Topics: Adenomatous Polyposis Coli; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Diabetes Complications; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Combinations; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Neoplasms, Multiple Primary; Oxonic Acid; Rectal Neoplasms; Remission Induction; Tegafur

2007
[A retrospective study of irinotecan plus fluorouracil and l-leucovorin chemotherapy for advanced and metastatic colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Rectal Neoplasms; Retrospective Studies

2007
[A case of advanced gastric cancer with obstructive jaundice due to multiple liver metastasis successfully treated with the following combination therapy of CPT-11 and cisplatin after combination therapy of paclitaxel and TS-1].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Administration Schedule; Drug Combinations; Humans; Irinotecan; Jaundice, Obstructive; Liver Neoplasms; Male; Middle Aged; Oxonic Acid; Paclitaxel; Stomach Neoplasms; Survivors; Tegafur

2007
[A case of TS-1 resistant recurrent gastric cancer with lung metastasis responding to TS-1 and irinotecan combination therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Drug Resistance, Neoplasm; Gastrectomy; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Oxonic Acid; Pancreas; Splenectomy; Stomach Neoplasms; Tegafur

2007
Developing strategies for liver metastases from colorectal cancer.
    Seminars in oncology, 2007, Volume: 34, Issue:2 Suppl 1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Catheter Ablation; Chemotherapy, Adjuvant; Colonic Neoplasms; Cryosurgery; Embolization, Therapeutic; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Portal Vein; Rectal Neoplasms; Remission Induction; Survival Rate; Time Factors; Topoisomerase I Inhibitors

2007
Panitumumab in metastatic colorectal cancer.
    Clinical advances in hematology & oncology : H&O, 2007, Volume: 5, Issue:1 Suppl 1

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Epidermal Growth Factor; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Panitumumab

2007
Reversible grade 4 hyperbilirubinemia in a patient with UGT1A1 7/7 genotype treated with irinotecan and cetuximab.
    Clinical colorectal cancer, 2007, Volume: 6, Issue:6

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Colonic Neoplasms; Fluorouracil; Genotype; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Irinotecan; Leucovorin; Liver Neoplasms; Male; Organoplatinum Compounds; Polymorphism, Genetic

2007
Interleukin-6 alters the cellular responsiveness to clopidogrel, irinotecan, and oseltamivir by suppressing the expression of carboxylesterases HCE1 and HCE2.
    Molecular pharmacology, 2007, Volume: 72, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antiviral Agents; Camptothecin; Carboxylesterase; Carboxylic Ester Hydrolases; Carcinoma, Hepatocellular; Cell Line, Tumor; Cells, Cultured; Clopidogrel; Dose-Response Relationship, Drug; Female; Hepatocytes; Humans; Interleukin-6; Irinotecan; Liver Neoplasms; Male; Middle Aged; Oseltamivir; Platelet Aggregation Inhibitors; RNA, Messenger; Ticlopidine

2007
[Long survival of a colon cancer case with multiple liver metastases cured by multidisciplinary therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Catheter Ablation; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Drug Combinations; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Organoplatinum Compounds; Oxonic Acid; Sigmoid Neoplasms; Survivors; Tegafur

2007
Role of repeated hepatectomy in the multimodal treatment of hepatic colorectal metastases.
    Archives of surgery (Chicago, Ill. : 1960), 2007, Volume: 142, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Female; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Reoperation; Retrospective Studies; Risk Factors; Survival Rate; Treatment Outcome

2007
Irinotecan activates p53 with its active metabolite, resulting in human hepatocellular carcinoma apoptosis.
    Journal of pharmacological sciences, 2007, Volume: 104, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; DNA Probes; Electrophoretic Mobility Shift Assay; Humans; In Situ Nick-End Labeling; Irinotecan; Liver Neoplasms; Oligonucleotides; Tumor Suppressor Protein p53

2007
[Complete remission of hepatic metastasis of gastric cancer with CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:7

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Administration Schedule; Drug Combinations; Gastrectomy; Humans; Irinotecan; Liver Neoplasms; Male; Oxonic Acid; Remission Induction; Stomach Neoplasms; Tegafur

2007
Irinotecan-induced apoptosis is inhibited by increased P-glycoprotein expression and decreased p53 in human hepatocellular carcinoma cells.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; In Situ Nick-End Labeling; Irinotecan; Liver Neoplasms; Microscopy, Fluorescence; Oligonucleotides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Tumor Suppressor Protein p53

2007
[A case of small cell carcinoma of the esophagus with remarkable response to chemotherapy with CPT-11 and CDDP].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2007, Volume: 104, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Small Cell; Cisplatin; Drug Administration Schedule; Esophageal Neoplasms; Humans; Irinotecan; Liver Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Remission Induction

2007
[Neuroendocrine carcinoma of the prostate effectively treated by cisplatin and irinotecan--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:8

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Neuroendocrine; Cisplatin; Drug Administration Schedule; Humans; Irinotecan; Liver Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Prostate-Specific Antigen; Prostatic Neoplasms

2007
[Efficacy of CPT-11 combined 5-FU/CF (FOLFIRI) regimen on advanced colorectal cancer].
    Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Diarrhea; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Nausea; Neoplasm Staging; Neutropenia; Rectal Neoplasms; Remission Induction; Retrospective Studies; Survival Rate; Young Adult

2007
Evaluation of irinotecan drug-eluting beads: a new drug-device combination product for the chemoembolization of hepatic metastases.
    Journal of controlled release : official journal of the Controlled Release Society, 2006, Nov-28, Volume: 116, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chemoembolization, Therapeutic; Drug Delivery Systems; Hepatic Artery; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Swine

2006
Resection of small bowel adenocarcinoma liver metastasis combined with neoadjuvant and adjuvant chemotherapy results in extended disease-free period--a case report.
    International journal of gastrointestinal cancer, 2006, Volume: 37, Issue:2-3

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Fluorouracil; Hepatectomy; Humans; Ileal Neoplasms; Irinotecan; Jejunal Neoplasms; Leucovorin; Liver Neoplasms; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Prognosis

2006
Development and characterization of a model of liver metastasis using human colon cancer HCT-116 cells.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:9

    Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Adhesion; Cell Line, Tumor; Collagen Type II; Colonic Neoplasms; Female; Fibronectins; Floxuridine; Fluorouracil; Humans; Irinotecan; Laminin; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Nude; Models, Biological; Neoplasm Metastasis; Paclitaxel

2007
Improved long-term outcome of surgery for advanced colorectal liver metastases: reasons and implications for management on the basis of a severity score.
    Annals of surgical oncology, 2008, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Postoperative Complications; Prospective Studies; Risk Factors; Survival Rate; Treatment Outcome

2008
Hepatic resection after rescue cetuximab treatment for colorectal liver metastases previously refractory to conventional systemic therapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Oct-10, Volume: 25, Issue:29

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Camptothecin; Cetuximab; Cohort Studies; Colorectal Neoplasms; Disease-Free Survival; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Treatment Outcome

2007
Hepatic arterial infusion plus systemic irinotecan in patients with unresectable hepatic metastases from colorectal cancer previously treated with systemic oxaliplatin: a retrospective analysis.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies

2007
[A case report--combination chemotherapy with oral UFT and CPT-11, 5-FU, l-LV by hepatic arterial infusion for multiple hepatic metastasis from sigmoid colon cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:13

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Middle Aged; Sigmoid Neoplasms; Tegafur; Uracil

2007
Addition of bevacizumab to irinotecan- and oxaliplatin-based preoperative chemotherapy regimens does not increase morbidity after resection of colorectal liver metastases.
    Journal of the American College of Surgeons, 2008, Volume: 206, Issue:1

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bevacizumab; Camptothecin; Colorectal Neoplasms; Drug Therapy, Combination; Female; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Morbidity; Organoplatinum Compounds; Oxaliplatin; Preoperative Care; Prodrugs; Treatment Outcome; United States; Vascular Endothelial Growth Factor A

2008
[Transarterial chemoembolization with irinotecan (CPT-11) and degradable starch microspheres (DSM) in patients with liver metastases from colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Camptothecin; Colorectal Neoplasms; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Middle Aged; Neoplasm Staging; Starch; Survival Rate

2007
[A case of multiple liver metastases from rectal cancer in poor performance status successfully treated with hepatic arterial infusion chemotherapy plus CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Male; Middle Aged; Rectal Neoplasms; Tomography, X-Ray Computed

2007
Preservation of the active lactone form of irinotecan using drug eluting beads for the treatment of colorectal cancer metastases.
    Journal of controlled release : official journal of the Controlled Release Society, 2008, Apr-07, Volume: 127, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Drug Delivery Systems; Drug Stability; Humans; Hydrogels; Hydrogen-Ion Concentration; Irinotecan; Kinetics; Lactones; Liver Neoplasms; Microspheres; Models, Chemical; Particle Size; Solubility

2008
Chemosensitivity determinants of irinotecan hydrochloride in hepatocellular carcinoma cell lines.
    Basic & clinical pharmacology & toxicology, 2008, Volume: 102, Issue:4

    Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Flavanones; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; Humans; Inhibitory Concentration 50; Irinotecan; Liver Neoplasms; Neoplasm Proteins; RNA, Messenger; Tetrahydroisoquinolines; Transfection

2008
Chemoembolisation of rat colorectal liver metastases with drug eluting beads loaded with irinotecan or doxorubicin.
    Clinical & experimental metastasis, 2008, Volume: 25, Issue:3

    Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; beta-Galactosidase; Blotting, Western; Camptothecin; Cell Proliferation; Chemoembolization, Therapeutic; Colorectal Neoplasms; Doxorubicin; Drug Delivery Systems; Irinotecan; Liver Neoplasms; Male; Microspheres; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Prodrugs; Rats

2008
Chronic myeloid leukemia following the treatment of rectal adenocarcinoma.
    Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:4

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Deoxycytidine; Fluorouracil; Fusion Proteins, bcr-abl; Humans; In Situ Hybridization, Fluorescence; Irinotecan; Leucovorin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Neoplasms; Male; Neoplasms, Second Primary; Organoplatinum Compounds; Oxaliplatin; Philadelphia Chromosome; Quinazolines; Rectal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Thiophenes

2008
[Multiple hepatic metastases and ovarian metastases of colon cancer responding to combined therapy with S-1 and CPT-11--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Combinations; Female; Humans; Irinotecan; Liver Neoplasms; Middle Aged; Ovarian Neoplasms; Oxonic Acid; Tegafur; Tomography, X-Ray Computed

2008
Assessing the optimal duration of chemotherapy in patients with colorectal liver metastases.
    Journal of surgical oncology, 2008, Jun-01, Volume: 97, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dexamethasone; Female; Floxuridine; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Retrospective Studies; Time Factors; Treatment Outcome

2008
[Recurrent gallbladder carcinoma treated with combination chemotherapy with gemcitabine, CPT-11 and S-1--a successful case with metastatic tumors replaced by marked calcification].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:5

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Calcinosis; Camptothecin; Deoxycytidine; Drug Combinations; Female; Gallbladder Neoplasms; Gemcitabine; Humans; Irinotecan; Liver Neoplasms; Neoplasm Recurrence, Local; Oxonic Acid; Tegafur

2008
Pathologic complete response to neoadjuvant FOLFOX in combination with bevacizumab in unresectable metastatic colorectal carcinoma.
    Clinical colorectal cancer, 2008, Volume: 7, Issue:2

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Neoadjuvant Therapy; Organoplatinum Compounds; Treatment Outcome

2008
Primary small cell carcinoma of the breast.
    Breast cancer (Tokyo, Japan), 2009, Volume: 16, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Camptothecin; Carboplatin; Carcinoma, Small Cell; Etoposide; Fatal Outcome; Female; Humans; Irinotecan; Liver Neoplasms; Mastectomy; Middle Aged; Neoplasm Recurrence, Local; Thoracic Wall

2009
[Antitumor effect of camptothecin analog on liver metastatic model of human colon cancer in nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Division; Colonic Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Tumor Cells, Cultured

1994
Chemotherapeutic agent CPT-11 induces the new expression of the apoptosis initiator to the cytoplasm.
    Experimental cell research, 1996, Aug-25, Volume: 227, Issue:1

    Topics: Amino Acid Sequence; Animals; Apoptosis; Camptothecin; Carcinoma, Hepatocellular; Caspase 1; Cell Extracts; Cell Nucleus; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoplasm; Dactinomycin; DNA; Humans; Irinotecan; Liver; Liver Neoplasms; Male; Molecular Sequence Data; Oligopeptides; Protein Synthesis Inhibitors; Rats; Tumor Cells, Cultured

1996
Antitumor effect of DX-8951, a novel camptothecin analog, on human pancreatic tumor cells and their CPT-11-resistant variants cultured in vitro and xenografted into nude mice.
    Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; DNA Fragmentation; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Irinotecan; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasm Proteins; Neoplasm Transplantation; Pancreatic Neoplasms; Prodrugs; Splenic Neoplasms; Topoisomerase I Inhibitors; Topotecan; Transplantation, Heterologous; Tumor Cells, Cultured

1997
A canalicular multispecific organic anion transporter (cMOAT) antisense cDNA enhances drug sensitivity in human hepatic cancer cells.
    Cancer research, 1997, Dec-15, Volume: 57, Issue:24

    Topics: Anion Transport Proteins; Antineoplastic Agents; ATP-Binding Cassette Transporters; Blotting, Western; Camptothecin; Carrier Proteins; Cisplatin; DNA, Antisense; DNA, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Glutathione Transferase; Humans; Irinotecan; Liver Neoplasms; Multidrug Resistance-Associated Proteins; Transfection; Tumor Cells, Cultured; Vincristine

1997
Irinotecan-induced immune thrombocytopenia.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Camptothecin; Colonic Neoplasms; Fluorouracil; Humans; Immunoglobulin G; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Thrombocytopenia

1998
[Effect of combination chemotherapy of low-dose CDDP. Continuous infusion of 5-FU, and intermittent CPT-11 administration for 2 advanced pancreatic cancer cases with liver metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:11

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Administration Schedule; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Pancreatic Neoplasms

1998
Irinotecan (CPT-11) metabolites in human bile and urine.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Bile; Camptothecin; Colonic Neoplasms; Female; Humans; Irinotecan; Liver Neoplasms; Mass Spectrometry; Middle Aged; Neoplasm Metastasis

1996
Diffuse mucosal damage in the large intestine associated with Irinotecan (CPT-11).
    Digestive diseases and sciences, 1998, Volume: 43, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Camptothecin; Colon; Colonic Neoplasms; Fatal Outcome; Humans; Intestinal Mucosa; Irinotecan; Liver Neoplasms; Male; Middle Aged

1998
4-[3,5-Bis(trimethylsilyl)benzamido] benzoic acid (TAC-101) inhibits the intrahepatic spread of hepatocellular carcinoma and prolongs the life-span of tumor-bearing animals.
    Clinical & experimental metastasis, 1998, Volume: 16, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Benzoates; Body Weight; Camptothecin; Carcinoma, Hepatocellular; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Nude; Molecular Structure; Neoplasm Invasiveness; Proto-Oncogene Proteins c-met; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; Specific Pathogen-Free Organisms; Survival Rate; Trimethylsilyl Compounds; Tumor Cells, Cultured

1998
Second line therapies move to the forefront in colorectal cancer.
    Journal of the National Cancer Institute, 1999, Jun-16, Volume: 91, Issue:12

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Cancer, Regional Perfusion; Clinical Trials, Phase III as Topic; Colorectal Neoplasms; Disease Progression; Disease-Free Survival; Fluorouracil; Hepatic Artery; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Multicenter Studies as Topic; Organoplatinum Compounds; Oxaliplatin; Time Factors; Treatment Outcome

1999
CPT-11 converting carboxylesterase and topoisomerase activities in tumour and normal colon and liver tissues.
    British journal of cancer, 1999, Volume: 80, Issue:3-4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Camptothecin; Carboxylic Ester Hydrolases; Colon; Colonic Neoplasms; DNA Topoisomerases, Type I; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Irinotecan; Liver; Liver Neoplasms; Male; Middle Aged; Rectal Neoplasms; Topoisomerase I Inhibitors

1999
[Three cases of multiple liver metastases of gastric cancer responding to tegafur/low-dose CDDP/CPT-11 combination chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:11

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Administration Schedule; Humans; Infusions, Intravenous; Injections, Intravenous; Irinotecan; Liver Neoplasms; Male; Stomach Neoplasms; Tegafur

1999
[Experimental study on intraperitoneal and intravenous administration of anti-tumor agents for liver metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:12

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cisplatin; Colonic Neoplasms; Fluorouracil; Infusions, Intravenous; Infusions, Parenteral; Irinotecan; Liver Neoplasms; Mice; Mice, Inbred BALB C; Tumor Cells, Cultured

1999
Hepatic tumor rupture following effectual treatment with irinotecan in a patient with highly refractory malignant lymphoma.
    International journal of hematology, 1999, Volume: 70, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Fatal Outcome; Humans; Irinotecan; Liver; Liver Neoplasms; Lymphoma, B-Cell; Male; Middle Aged; Rupture; Tumor Lysis Syndrome

1999
Therapy of human pancreatic carcinoma implants by irinotecan and the oral immunomodulator JBT 3002 is associated with enhanced expression of inducible nitric oxide synthase in tumor-infiltrating macrophages.
    Cancer research, 2000, Jan-01, Volume: 60, Issue:1

    Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Drug Therapy, Combination; Humans; In Situ Nick-End Labeling; Injections, Intralesional; Irinotecan; Lipopeptides; Lipoproteins; Liver Neoplasms; Lymph Nodes; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pancreatic Neoplasms; Proliferating Cell Nuclear Antigen; Transplantation, Heterologous; Tumor Cells, Cultured

2000
[A case of advanced gastric cancer with lung and liver metastasis responding remarkably to combination chemotherapy with CDDP and CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Drug Administration Schedule; Humans; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Stomach Neoplasms

2000
Dramatic tumor response of bulky liver metastases following treatment with CPT-11 and a chronomodulated 4-day infusion of 5-fluorouracil, folinic acid and oxaliplatin every 2 weeks in a colorectal cancer patient.
    Anti-cancer drugs, 2000, Volume: 11, Issue:4

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chronotherapy; Female; Fluorouracil; Humans; Infusions, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Sigmoid Neoplasms; Tomography, X-Ray Computed; Treatment Outcome

2000
[A case of metastatic colon carcinoma in which a continuous intrahepatic artery-infusion of 5-FU leucovorin and cisplatin, and systemic chemotherapy with CPT-11 was very effective].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colonic Neoplasms; Drug Administration Schedule; Fluorouracil; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged

2000
Complete remission of unresectable hepatocellular carcinoma on healthy liver by the combination of aggressive surgery and high-dose-intensity chemotherapy by CPT-11.
    Anti-cancer drugs, 2000, Volume: 11, Issue:8

    Topics: alpha-Fetoproteins; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma, Hepatocellular; Combined Modality Therapy; DNA Topoisomerases, Type I; Female; Hepatectomy; Humans; Irinotecan; Liver Neoplasms; Middle Aged; Remission Induction

2000
[Experimental study on intraperitoneal versus intravenous CPT-11 for peritoneal seeding and liver metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Colonic Neoplasms; Female; Infusions, Intravenous; Infusions, Parenteral; Irinotecan; Liver Neoplasms; Mice; Mice, Inbred BALB C; Peritoneal Neoplasms

2000
[Three cases of liver metastasis of colon cancer responding to systemic combination chemotherapy utilizing CPT-11].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:14

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Humans; Irinotecan; Liver Neoplasms; Male; Tegafur; Uracil

2000
Pharmacokinetics of orally administered camptothecins.
    Annals of the New York Academy of Sciences, 2000, Volume: 922

    Topics: Administration, Oral; Anion Transport Proteins; Antineoplastic Agents, Phytogenic; Biological Transport, Active; Biotransformation; Caco-2 Cells; Camptothecin; Carrier Proteins; Cell Membrane Permeability; Colonic Neoplasms; Enzyme Inhibitors; Humans; Hydrolysis; Intestinal Absorption; Intestinal Mucosa; Irinotecan; Liver; Liver Neoplasms; Probenecid; Prodrugs; Rectal Neoplasms

2000
[Chemotherapy by combination of low-dose CPT-11 and PSK in an elderly man with liver metastasis from gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Humans; Immunologic Factors; Irinotecan; Liver Neoplasms; Male; Proteoglycans; Stomach Neoplasms

2001
Safe administration of irinotecan, oxaliplatin and raltitrexed in a DPD-deficient patient with metastatic colon cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Humans; Irinotecan; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxidoreductases; Quinazolines; Thiophenes

2001
Toxicity of irinotecan (CPT-11) and hepato-renal dysfunction.
    Anti-cancer drugs, 2001, Volume: 12, Issue:7

    Topics: Adenocarcinoma; Adenomatous Polyposis Coli Protein; Antineoplastic Agents, Phytogenic; Camptothecin; Cecal Neoplasms; Chemical and Drug Induced Liver Injury; Humans; Irinotecan; Kidney; Kidney Diseases; Liver; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Topoisomerase I Inhibitors

2001
Non-operative management of the primary tumour in patients with incurable stage IV colorectal cancer.
    The British journal of surgery, 2001, Volume: 88, Issue:10

    Topics: Abdominal Pain; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Humans; Intestinal Obstruction; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Survival Analysis; Tomography, X-Ray Computed

2001
[Sigmoid colon cancer with multiple liver metastasis (H3) effectively treated with CPT-11 and DSM (degradable starch microsphere) HAI therapy and intensive high dosage 5-FU HAI therapy--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Irinotecan; Liver Neoplasms; Middle Aged; Sigmoid Neoplasms; Starch

2001
[Four cases of multiple liver metastasis of colorectal cancer treated with hepatic resection after chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Colorectal Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Prognosis; Survival Rate

2001
[Two cases of multiple liver metastases of colon cancer with systemic irinotecan and hepatic arterial injection of 5-FU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Drug Administration Schedule; Fluorouracil; Humans; Irinotecan; Liver Neoplasms; Male

2001
[A case of lung metastasis from colon cancer treated successfully with combined chemotherapy of CPT-11 and 5'-DFUR].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Administration Schedule; Female; Floxuridine; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Middle Aged

2001
Fighting wars, winning battles.
    Annals of surgical oncology, 2002, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Combined Modality Therapy; Cryosurgery; Disease-Free Survival; Floxuridine; Humans; Irinotecan; Liver Neoplasms

2002
Weekly irinotecan in a patient with metastatic colorectal cancer on hemodialysis due to chronic renal failure.
    Onkologie, 2002, Volume: 25, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Chemotherapy, Adjuvant; Colectomy; Colorectal Neoplasms; Combined Modality Therapy; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Humans; Infusions, Intra-Arterial; Irinotecan; Kidney Failure, Chronic; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Renal Dialysis

2002
[A case of hepatic metastasis from rectal carcinoma successfully treated with pharmacokinetic modulating chemotherapy (PMC)-CPT-11 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Camptothecin; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil; Hepatic Artery; Humans; Hysterectomy; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Middle Aged; Neoplasm Invasiveness; Rectal Neoplasms; Sigmoid Neoplasms

2002
Anaphylactic shock secondary to intravenous administration of folinic acid: a first report.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:3

    Topics: Aged; Aged, 80 and over; Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Fluorouracil; Humans; Injections, Intravenous; Irinotecan; Leucovorin; Liver Neoplasms; Lung Neoplasms; Male; Treatment Outcome

2002
[A case of rectal cancer with multiple liver metastases that responded dramatically to pharmacokinetic modulating chemotherapy/CPT-11 therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Hepatic Artery; Humans; Infusion Pumps, Implantable; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms; Male; Rectal Neoplasms; Tegafur; Uracil

2002
[Inhibitory effects of CPT-11 on liver metastases in nude mice injected with human pancreatic tumor cells into their spleens].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Division; Depression, Chemical; Drug Screening Assays, Antitumor; Female; Humans; Irinotecan; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Spleen; Tumor Cells, Cultured

1990