Page last updated: 2024-08-24

irinotecan and Cancer of Intestines

irinotecan has been researched along with Cancer of Intestines in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's6 (35.29)29.6817
2010's8 (47.06)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Ando, M; Bando, H; Hara, K; Honda, K; Kadowaki, S; Kato, K; Kumanishi, R; Masuishi, T; Matsubara, Y; Muro, K; Nakazawa, T; Narita, Y; Nozawa, K; Ogata, T; Tajika, M1
Afchain, P; Baudin, E; Desgrippes, R; Hadoux, J; Hautefeuille, V; Lepage, C; Lorgis, V; Monterymard, C; Scoazec, JY; Thuillier, F; Tougeron, D; Walter, T1
Ames, MM; Foster, NR; Goetz, MP; Hobday, TJ; Horvath, LE; Jatoi, A; Mahoney, MR; McWilliams, RR; Meyers, JP; Murray, JA; Schneider, DJ; Smyrk, TC1
Boku, N; Hamaguchi, T; Higuchi, K; Honma, Y; Iwasa, S; Kato, K; Shoji, H; Takashima, A; Yamaguchi, T1
Boudreaux, JP; Ramirez, RA; Thiagarajan, R; Thomas, KEH; Voros, BA; Woltering, EA1
Ajioka, Y; Aoki, M; Fukunari, H; Hayashi, T; Saito, S; Shitara, K; Tani, Y; Watanabe, A1
Gao, J; Gong, J; Li, J; Li, Y; Li, Z; Liu, Y; Lu, M; Lu, Z; Shen, L; Wang, X; Yang, L; Zhang, X; Zhou, J1
Abe, T; Fukushima, T; Hamaguchi, Y; Masui, H; Mogaki, M; Nagahori, K; Nagahori, Y1
Chin, K; Hatake, K; Konishi, F; Matsusaka, S; Mizunuma, N; Muto, T; Oya, M; Shinozaki, E; Suenaga, M; Ueno, M; Yamaguchi, T1
Eguchi-Nakajima, T; Hamaguchi, T; Hirashima, Y; Kato, K; Morizane, C; Okita, N; Ono, M; Shimada, Y; Shirao, K; Takahari, D; Takashima, A; Yamada, Y1
Dasanu, CA; Trikudanathan, G1
Fratto, ME; Galluzzo, S; Russo, A; Santini, D; Spoto, C; Tonini, G; Vincenzi, B; Zoccoli, A1
Boku, N; Honma, Y; Kato, S; Kawai, H; Morita, S; Nishina, T; Suenaga, M; Taguri, M; Takahashi, H; Tamura, F; Tsushima, T; Ueda, S1
Zhang, L1
Dubois, RN; Hatakeyama, N; Horikawa, Y; Jin, M; Komatsu, K; Matsuhashi, T; Odashima, M; Ohba, R; Otaka, M; Oyake, J; Wada, I; Watanabe, S1
Caron, P; Liu, D; Patel, S; Seiter, K1
Erlichman, C; Kaufmann, SH; Mullany, S; Svingen, PA1

Reviews

2 review(s) available for irinotecan and Cancer of Intestines

ArticleYear
Current Treatment Options in Gastroenteropancreatic Neuroendocrine Carcinoma.
    The oncologist, 2019, Volume: 24, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Neuroendocrine; Cisplatin; Clinical Trials as Topic; Etoposide; Humans; Intestinal Neoplasms; Irinotecan; Neuroendocrine Tumors; Pancreatic Neoplasms; Prognosis; Progression-Free Survival; Radiopharmaceuticals; Stomach Neoplasms

2019
Evolving pharmacotherapeutic strategies for small bowel adenocarcinoma.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:10

    Topics: Adenocarcinoma; Camptothecin; Clinical Trials as Topic; Fluorouracil; Humans; Intestinal Neoplasms; Intestine, Small; Irinotecan

2010

Trials

3 trial(s) available for irinotecan and Cancer of Intestines

ArticleYear
FOLFIRINEC: a randomized phase II trial of mFOLFIRINOX vs platinum-etoposide for metastatic neuroendocrine carcinoma of gastroenteropancreatic or unknown origin.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2021, Volume: 53, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Carcinoma, Neuroendocrine; Etoposide; Female; Fluorouracil; Humans; Intestinal Neoplasms; Irinotecan; Leucovorin; Male; Neoplasm Metastasis; Neoplasms, Unknown Primary; Neuroendocrine Tumors; Oxaliplatin; Pancreatic Neoplasms; Platinum Compounds; Progression-Free Survival; Prospective Studies; Quality of Life; Stomach Neoplasms; Survival Rate; Treatment Outcome

2021
North Central Cancer Treatment Group N0543 (Alliance): A phase 2 trial of pharmacogenetic-based dosing of irinotecan, oxaliplatin, and capecitabine as first-line therapy for patients with advanced small bowel adenocarcinoma.
    Cancer, 2017, Sep-15, Volume: 123, Issue:18

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cancer Care Facilities; Capecitabine; Databases, Factual; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Genotype; Glucuronosyltransferase; Humans; Intestinal Neoplasms; Intestine, Small; Irinotecan; Kaplan-Meier Estimate; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Pharmacogenetics; Prognosis; Proportional Hazards Models; Retrospective Studies; Survival Analysis

2017
Irinotecan plus cisplatin followed by octreotide long-acting release maintenance treatment in advanced gastroenteropancreatic neuroendocrine carcinoma: IPO-NEC study.
    Oncotarget, 2017, Apr-11, Volume: 8, Issue:15

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Camptothecin; Cisplatin; Female; Humans; Induction Chemotherapy; Intestinal Neoplasms; Irinotecan; Maintenance Chemotherapy; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Neuroendocrine Tumors; Octreotide; Pancreatic Neoplasms; Stomach Neoplasms; Survival Rate; Treatment Outcome

2017

Other Studies

12 other study(ies) available for irinotecan and Cancer of Intestines

ArticleYear
Second-line Chemotherapy for Previously Treated Metastatic Small Bowel Adenocarcinoma: A Retrospective Analysis.
    Anticancer research, 2021, Volume: 41, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Follow-Up Studies; Humans; Intestinal Neoplasms; Intestine, Small; Irinotecan; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Retrospective Studies; Survival Rate; Taxoids

2021
Association between UGT1A1 gene polymorphism and safety and efficacy of irinotecan monotherapy as the third-line treatment for advanced gastric cancer.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2019, Volume: 22, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Female; Follow-Up Studies; Glucuronosyltransferase; Humans; Intestinal Neoplasms; Irinotecan; Lymphatic Metastasis; Male; Middle Aged; Polymorphism, Genetic; Prognosis; Retrospective Studies; Salvage Therapy; Stomach Neoplasms; Survival Rate

2019
[A Case of Choriocarcinoma of the Small Intestine with Multiple Lung and Liver Metastases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2018, Volume: 45, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Cisplatin; Humans; Intestinal Neoplasms; Irinotecan; Liver Neoplasms; Male

2018
[Efficacy of low-dose CDDP and CPT-11 for patients with intestinal type of gastric adenocarcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Gastroscopy; Humans; Intestinal Neoplasms; Irinotecan; Male; Middle Aged; Stomach Neoplasms; Tomography, X-Ray Computed; Treatment Failure

2008
Chemotherapy for small-bowel Adenocarcinoma at a single institution.
    Surgery today, 2009, Volume: 39, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Disease Progression; Female; Fluorouracil; Follow-Up Studies; Humans; Intestinal Neoplasms; Intestine, Small; Irinotecan; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Retrospective Studies; Survival Rate; Tomography, X-Ray Computed; Vitamin B Complex

2009
Combination chemotherapy with cisplatin and irinotecan in patients with adenocarcinoma of the small intestine.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2008, Volume: 11, Issue:4

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Duodenal Neoplasms; Female; Humans; Ileal Neoplasms; Intestinal Neoplasms; Irinotecan; Jejunal Neoplasms; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Metastasis

2008
Cetuximab in small bowel adenocarcinoma: a new friend?
    British journal of cancer, 2010, Oct-12, Volume: 103, Issue:8

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cetuximab; Combined Modality Therapy; Female; Humans; Immunotherapy; Intestinal Neoplasms; Intestine, Small; Irinotecan; Male; Middle Aged; Survival

2010
Multicenter retrospective study of 132 patients with unresectable small bowel adenocarcinoma treated with chemotherapy.
    The oncologist, 2012, Volume: 17, Issue:9

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Disease-Free Survival; Female; Humans; Intestinal Neoplasms; Intestine, Small; Irinotecan; Japan; Male; Middle Aged; Multivariate Analysis; Organoplatinum Compounds; Oxaliplatin; Pyrimidines; Retrospective Studies

2012
[Campto (CPT-11) treatment of advanced large intestinal cancer: clinical experience].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2003, Volume: 25, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Camptothecin; Female; Humans; Intestinal Neoplasms; Irinotecan; Male; Middle Aged

2003
MEK activation suppresses CPT11-induced apoptosis in rat intestinal epithelial cells through a COX-2-dependent mechanism.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:10

    Topics: Animals; Apoptosis; Blotting, Western; Camptothecin; Cell Survival; Cyclooxygenase 2; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Intestinal Mucosa; Intestinal Neoplasms; Irinotecan; Mitogen-Activated Protein Kinase Kinases; Neoplasms, Experimental; Rats; Signal Transduction; Tumor Cells, Cultured

2007
Acute myelogenous leukemia following irinotecan-based chemotherapy for adenocarcinoma of the small intestine.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:5

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Fluorouracil; Humans; Intestinal Neoplasms; Intestine, Small; Irinotecan; Leucovorin; Leukemia, Myeloid, Acute; Male; Prognosis; Recurrence; Remission Induction

2007
Effect of adding the topoisomerase I poison 7-ethyl-10-hydroxycamptothecin (SN-38) to 5-fluorouracil and folinic acid in HCT-8 cells: elevated dTTP pools and enhanced cytotoxicity.
    Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Cycle; Cell Survival; Deoxyuracil Nucleotides; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Fluorouracil; Humans; Intestinal Neoplasms; Irinotecan; Leucovorin; Thymidylate Synthase; Thymine Nucleotides; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1998