iridoids has been researched along with Wounds-and-Injuries* in 2 studies
2 other study(ies) available for iridoids and Wounds-and-Injuries
| Article | Year |
|---|---|
A genipin-crosslinked gelatin membrane as wound-dressing material: in vitro and in vivo studies.
A naturally occurring crosslinking agent (genipin) was used in this study to crosslink gelatin hydrogel to develop a wound-dressing membrane. The study was to investigate the in vitro characteristics of the genipin-crosslinked gelatin membrane. The glutaraldehyde-crosslinked counterpart, at a similar crosslinking degree, was used as control. Additionally, an in vivo experiment was undertaken to study the wound healings covered with the glutaraldehyde- and genipin-crosslinked dressings in a rat model. The in vitro results obtained suggested that crosslinking of gelatin membranes with glutaraldehyde or genipin may produce distinct crosslinking structures. The differences in crosslinking structure can significantly affect the mechanical property, water-vapor-transmission rate, swelling ratio, degradation against enzyme and cellular compatibility of the crosslinked membranes. In the in vivo study, it was found that the degree of inflammatory reaction for the wound treated with the genipin-crosslinked dressing was significantly less severe than that covered with the glutaraldehyde-crosslinked dressing throughout the entire course of the study. Additionally, the healing rate for the wound treated with the genipin-crosslinked dressing was notably faster than its glutaraldehyde-crosslinked counterpart. Topics: Animals; Bandages; Biocompatible Materials; Cell Line; Cross-Linking Reagents; Fibroblasts; Gelatin; Glutaral; Humans; Inflammation; Iridoid Glycosides; Iridoids; Male; Membranes, Artificial; Microscopy, Electron, Scanning; Pyrans; Rats; Rats, Wistar; Tensile Strength; Water; Wound Healing; Wounds and Injuries | 2003 |
[Screening studies on anti-inflammatory function of traditional Chinese herb Gardenia jasminoides Ellis and its possibility in treating soft tissue injuries in animals].
This paper reports the study of six fractions and one chemical constituent isolated from the traditional Chinese herb Gardenia jasminoides. The results showed that two fractions (G5.G6,), alcohol extract (G1) and genipoiside(A) had obvious anti-inflammatory effects and were comparatively effective in treating soft tissue injuries in animals. Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Buttocks; Drugs, Chinese Herbal; Iridoids; Male; Mice; Pyrans; Rabbits; Rats; Wounds and Injuries | 1991 |