iridoids has been researched along with Leukemia-P388* in 3 studies
3 other study(ies) available for iridoids and Leukemia-P388
| Article | Year |
|---|---|
Two phenylpropanoid glycosides from Neopicrorhiza scrophulariiflora.
Two new phenylpropanoid glycosides, scrophulosides A (1) and B (2), were isolated from the rhizomes of Neopicrorhiza scrophulariiflora (Scrophulariaceae), along with two known compounds, androsin (3) and picroside I. Their structures were elucidated on the basis of both chemical and spectroscopic data. Topics: Animals; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Cinnamates; Drug Screening Assays, Antitumor; Glycosides; Iridoid Glucosides; Iridoids; Leukemia P388; Mice; Plant Extracts; Plant Roots; Scrophulariaceae; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 2006 |
Traditional medicinal plants of Thailand. XVII. Biologically active constituents of Plumeria rubra.
The compounds 1-6 were isolated from the heartwood of Plumeria rubra, following bioactivity-directed fractionation. Plumericin 1 and isoplumericin 2 displayed molluscicidal, cytotoxic and antibacterial activity, 4-hydroxyacetophenone 3 was weakly cytotoxic, whereas the remaining glycosidic isolates (plumieride, 4; 13-O-coumaroylplumieride, 5; protoplumericine A, 6) were inactive in all test systems. Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Indenes; Iridoids; Leukemia P388; Medicine, Traditional; Microbial Sensitivity Tests; Structure-Activity Relationship; Thailand | 1991 |
Studies on iridoid-related compounds. V. Antitumor activity of iridoid dervs. periodate oxidation products.
In the course of a modification study of iridoid glucosides to investigate their antitumor and antimicrobial activity, we found that about all metaperiodate oxidation products of iridoid glucosides which had no antitumor activity showed potent activity against the leukemia P388 in mice. They were found to be more active than the corresponding aglycones obtained by enzymic hydrolysis of iridoid glucosides. Among them, periodate oxidation product of sweroside showed the most potent activity, of which the maximum total/control (T/C) value was 198% at 200 mg/kg. Topics: Animals; Bacteria; Glucosides; Glycosides; Iridoids; Leukemia P388; Leukemia, Experimental; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Oxidation-Reduction; Periodic Acid; Pyrans; Structure-Activity Relationship | 1988 |