Compounds > iproniazid
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iproniazid and Acute Liver Injury, Drug-Induced

iproniazid has been researched along with Acute Liver Injury, Drug-Induced in 37 studies

Research Excerpts

ExcerptRelevanceReference
"Drug-induced autoimmune diseases have two immunological peculiarities."2.37[Autoimmunity induced by drugs. Immunological characteristics and etiopathogenic hypotheses]. ( Homberg, JC, 1984)
" We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts."1.37FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011)
" An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems."1.36Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199021 (56.76)18.7374
1990's4 (10.81)18.2507
2000's1 (2.70)29.6817
2010's11 (29.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Greene, N1
Fisk, L1
Naven, RT1
Note, RR1
Patel, ML1
Pelletier, DJ1
Morgan, RE2
Trauner, M1
van Staden, CJ2
Lee, PH1
Ramachandran, B1
Eschenberg, M1
Afshari, CA2
Qualls, CW1
Lightfoot-Dunn, R1
Hamadeh, HK2
Ekins, S1
Williams, AJ1
Xu, JJ1
Chen, M2
Vijay, V1
Shi, Q2
Liu, Z2
Fang, H2
Tong, W3
Dawson, S1
Stahl, S2
Paul, N1
Barber, J1
Kenna, JG2
Ding, D1
Kelly, R1
Sakatis, MZ1
Reese, MJ1
Harrell, AW1
Taylor, MA1
Baines, IA1
Chen, L1
Bloomer, JC1
Yang, EY1
Ellens, HM1
Ambroso, JL1
Lovatt, CA1
Ayrton, AD1
Clarke, SE1
Warner, DJ1
Chen, H1
Cantin, LD1
Walker, CL1
Noeske, T1
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
BERNSTEIN, A1
SIMON, F1
SCHALM, L1
SAPHIER, E1
COOK, GC1
SHERLOCK, S1
WOROBEC, T1
Rubio Barbón, S1
León Durán, D1
Arias Miranda, I1
Homberg, JC4
Danan, G1
Bernuau, J2
Roche-Sicot, J1
Pessayre, D2
Stelly, N1
Andreis, I1
Abuaf, N1
Saadoun, F1
Andre, J1
Valerdiz Casasola, S1
Linares Rodríguez, A1
Recarte Alvarez, J1
Rodrigo Sáez, L1
Capron, JP1
Gineston, JL1
Opolon, P1
Dupas, JL1
Denis, J1
Quénum, C1
Lorriaux, A1
Matsuki, Y1
Bandou, R1
Kiwada, H1
Maeda, H1
Goromaru, T1
Pons, C1
Dansette, PM1
Gregeois, J1
Billett, EE1
Mansuy, D1
Maille, F1
Duvoux, C1
Cherqui, D1
Radier, C1
Zafrani, ES1
Dhumeaux, D1
Nelson, SD1
Mitchell, JR2
Timbrell, JA2
Snodgrass, WR2
Corcoran, GB1
de Saint-Louvent, P1
Degott, C1
Rueff, B1
Benhamou, JP1
Gillette, JR1
Gollini, C1
Dallari, R1
Cervi, F1
Mengoli, M1
Schläppi, B1
Ruckebusch, Y1
Grivel, ML1
Lajeunesse, BS1
Babior, BM1
Davidson, CS1
Zimmerman, HJ2
Bondar', ZA1
Podymova, SD1

Reviews

4 reviews available for iproniazid and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016
[Autoimmunity induced by drugs. Immunological characteristics and etiopathogenic hypotheses].
    Presse medicale (Paris, France : 1983), 1984, Dec-15, Volume: 13, Issue:45

    Topics: Animals; Autoimmune Diseases; Cardiac Glycosides; Chemical and Drug Induced Liver Injury; Drug Combi

1984
The role of metabolism in the hepatotoxicity of isoniazid and iproniazid.
    Drug metabolism reviews, 1979, Volume: 10, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cobalt; Humans; Hydrazines; Iproniazid; Isoniazid;

1979
[Drug-induced hepatitis].
    Terapevticheskii arkhiv, 1970, Volume: 42, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Antimetabolites; Chemical and Drug Induced Liver Injury; Contraceptive

1970

Other Studies

33 other studies available for iproniazid and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship;

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
Chlorpromazine and iproniazid toxic hepatitis in the same patient.
    A.M.A. archives of internal medicine, 1959, Volume: 103, Issue:6

    Topics: Chemical and Drug Induced Liver Injury; Chlorpromazine; Hepatitis; Hepatitis A; Iproniazid; Niacin;

1959
[LIVER DAMAGE BY DRUGS].
    Nederlands tijdschrift voor geneeskunde, 1963, Dec-07, Volume: 107

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Arsphenamine; Chemical and Drug Induced Liver Injury; Chl

1963
ANTIDEPRESSANT DRUGS AND LIVER DAMAGE.
    British medical journal, 1964, Apr-11, Volume: 1, Issue:5388

    Topics: Antidepressive Agents; Chemical and Drug Induced Liver Injury; Chlorpromazine; Hepatitis; Hepatitis

1964
JAUNDICE AND ITS RELATION TO THERAPEUTIC AGENTS.
    Lancet (London, England), 1965, Jan-23, Volume: 1, Issue:7378

    Topics: Alkaline Phosphatase; Antidepressive Agents; Aspartate Aminotransferases; Bilirubin; Chemical and Dr

1965
BLOOD DYSCRASIAS ASSOCIATED WITH ANTITUBERCULOSIS AND/OR TRANQUILIZING CHEMOTHERAPY. A LONG-TERM CLINICAL OBSERVATION.
    Diseases of the chest, 1965, Volume: 47

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver In

1965
[Antidepressant-induced toxic hepatitis].
    Gastroenterologia y hepatologia, 2008, Volume: 31, Issue:1

    Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Iproniazid; Monoamine Oxidase Inhibit

2008
[Iproniazid-induced hepatitis. The diagnostic value of a new antimitochondrial antibody anti-M6].
    Gastroenterologie clinique et biologique, 1983, Volume: 7, Issue:5

    Topics: Adult; Antibodies; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female; Humans

1983
A new antimitochondria antibody (anti-M6) in iproniazid-induced hepatitis.
    Clinical and experimental immunology, 1982, Volume: 47, Issue:1

    Topics: Adult; Aged; Animals; Autoantibodies; Chemical and Drug Induced Liver Injury; Female; Fluorescent An

1982
[Hepatitis caused by drugs. 4].
    Revista espanola de las enfermedades del aparato digestivo, 1982, Volume: 62, Issue:4

    Topics: Adult; Aminosalicylic Acid; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Halothane

1982
[Iproniazid-prochlorperazine fulminant hepatitis (author's transl)].
    Gastroenterologie clinique et biologique, 1980, Volume: 4, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination;

1980
Effects of ascorbic acid on iproniazid-induced hepatitis in phenobarbital-treated rats.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:8

    Topics: Alanine Transaminase; Aminopyrine; Animals; Ascorbic Acid; Aspartate Aminotransferases; Chemical and

1994
Human anti-mitochondria autoantibodies appearing in iproniazid-induced immunoallergic hepatitis recognize human liver monoamine oxidase B.
    Biochemical and biophysical research communications, 1996, Jan-05, Volume: 218, Issue:1

    Topics: Antibody Specificity; Antigen-Antibody Reactions; Autoantibodies; Chemical and Drug Induced Liver In

1996
[Auxiliary hepatic transplantation in iproniazid-induced subfulminant hepatitis. Should iproniazid still be sold in France?].
    Gastroenterologie clinique et biologique, 1999, Volume: 23, Issue:10

    Topics: Adult; Antidepressive Agents; Chemical and Drug Induced Liver Injury; Female; Follow-Up Studies; Hum

1999
Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat.
    Science (New York, N.Y.), 1976, Sep-03, Volume: 193, Issue:4256

    Topics: Animals; Chemical and Drug Induced Liver Injury; Humans; Hydrazines; Iproniazid; Isoniazid; Microsom

1976
Iproclozide fulminant hepatitis. Possible role of enzyme induction.
    Gastroenterology, 1978, Volume: 75, Issue:3

    Topics: Adult; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Consciousness Disorder

1978
The role of biotransformation in chemical-induced liver injury.
    Environmental health perspectives, 1976, Volume: 15

    Topics: Acetaminophen; Animals; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; Cr

1976
[Iproniazid-induced acute hepatitis].
    Recenti progressi in medicina, 1992, Volume: 83, Issue:6

    Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Humans; Iproniazid; Male; Prognosis

1992
The lack of hepatotoxicity in the rat with the new and reversible MAO-A inhibitor moclobemide in contrast to iproniazid.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:5

    Topics: Animals; Benzamides; Body Weight; Chemical and Drug Induced Liver Injury; Iproniazid; Liver; Male; M

1985
[Hepatic insufficiency and neurotropic medicinal activity].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1966, Volume: 160, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Dogs; Drug Synergism; Female; Hexobarbital; Ipronia

1966
[True and false adverse effects of thymoanaleptic medications].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1968, Dec-08, Volume: 44, Issue:51

    Topics: Amitriptyline; Antidepressive Agents; Chemical and Drug Induced Liver Injury; Cholestasis; Depressio

1968
Hepatitis: drug or viral?
    The American journal of medicine, 1966, Volume: 41, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Halothane; Hepatitis A; Humans; Ipr

1966
The spectrum of hepatotoxicity.
    Perspectives in biology and medicine, 1968,Autumn, Volume: 12, Issue:1

    Topics: Aminosalicylic Acids; Anti-Bacterial Agents; Antimetabolites; Benzene Derivatives; Carbon Tetrachlor

1968
Toxic hepatopathy.
    The American journal of gastroenterology, 1968, Volume: 49, Issue:1

    Topics: Aminosalicylic Acids; Anabolic Agents; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Arseni

1968