ipriflavone has been researched along with Otosclerosis in 3 studies
ipriflavone : A member of the class of isoflavones that is isoflavone in which the hydrogen at position 7 is replaced by an isopropoxy group. A synthetic isoflavone, it was formerly used for the treatment of osteoporosis, although a randomised controlled study failed to show any benefit. It is still used to prevent osteoporosis in post-menopausal women.
Otosclerosis: Formation of spongy bone in the labyrinth capsule which can progress toward the STAPES (stapedial fixation) or anteriorly toward the COCHLEA leading to conductive, sensorineural, or mixed HEARING LOSS. Several genes are associated with familial otosclerosis with varied clinical signs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ipriflavone, an isoflavone synthesized from the soy isoflavone daidzein, holds great promise in the prevention and treatment of osteoporosis and other metabolic bone diseases." | 4.80 | Ipriflavone: an important bone-building isoflavone. ( Head, KA, 1999) |
| "Quercetin, which has a better than Ipriflavone water-solubility seems as promising as Ipriflavone in the control of the otosclerotic bone-remodelling disturbance." | 1.29 | Flavonoids alter bone-remodelling in auditory ossicle organ cultures. ( Ribári, O; Sziklai, I, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sziklai, I | 2 |
| Ribári, O | 2 |
| Head, KA | 1 |
1 review available for ipriflavone and Otosclerosis
| Article | Year |
|---|---|
Ipriflavone: an important bone-building isoflavone.
Topics: Bone Remodeling; Drug Therapy, Combination; Female; Humans; Hyperparathyroidism; Isoflavones; Osteit | 1999 |
2 other studies available for ipriflavone and Otosclerosis
| Article | Year |
|---|---|
Flavonoids alter bone-remodelling in auditory ossicle organ cultures.
Topics: Animals; Bone Resorption; Collagen; Culture Techniques; Dinoprostone; Flavonoids; Guinea Pigs; Isofl | 1995 |
The effect of flavone treatment on human otosclerotic ossicle organ cultures.
Topics: Adult; Collagen; Culture Techniques; Female; Flavonoids; Humans; Isoflavones; Male; Middle Aged; Oto | 1985 |