ipodate has been researched along with Basedow Disease in 19 studies
Ipodate: Ionic monomeric contrast media. Usually the sodium or calcium salts are used for examination of the gall bladder and biliary tract. (From Martindale, The Extra Pharmacopoeia, 30th ed, p704)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Consecutive patients with hyperthyroidism caused by Graves' disease or by multinodular toxic goiter were randomized to be treated with high-dose propylthiouracil (PTU) to block D1, PTU plus KI, or PTU plus sodium ipodate to additionally block D2." | 9.12 | Sources of circulating 3,5,3'-triiodothyronine in hyperthyroidism estimated after blocking of type 1 and type 2 iodothyronine deiodinases. ( Christensen, SE; Helleberg, K; Laurberg, P; Nielsen, S; Pedersen, KM; Seefeldt, T; Vestergaard, H, 2007) |
| "We describe the effect of administration of repeated doses of sodium ipodate in a newborn infant with hyperthyroidism due to transient Graves' disease." | 7.67 | Treatment of neonatal hyperthyroidism due to Graves' disease with sodium ipodate. ( Filetti, S; Fisher, DA; Karpman, BA; Rapoport, B, 1987) |
| "A dose (3 g) of sodium ipodate used routinely in oral cholecystography caused a fall in serum 3,5,3'-triiodothyronine and a rise in serum 3,3',5'-triiodothyronine in three patients taking thyroxine (T4), four euthyroid subjects,and four hyperthyroid patients." | 7.66 | Changes in circulating iodothyronines in euthyroid and hyperthyroid subjects given ipodate (Oragrafin), an agent for oral cholecystography. ( Bennett, LR; Chopra, IJ; Solomon, DH; Wu, SY, 1978) |
| "No ipodate was discontinued in the eight patients who did not respond, and they were then treated with MMI." | 5.29 | Sodium ipodate and methimazole in the long-term treatment of hyperthyroid Graves' disease. ( Bianconi, L; Braverman, LE; Gardini, E; Minelli, R; Roti, E, 1993) |
| "Patients with thyrotoxic Graves' disease were treated daily for 10 d with 1 g sodium ipodate, an iodine rich X-ray contrast agent which impairs outer ring (5'-) deiodination of T4 to T3, or with 12 drops of a saturated solution of potassium iodide (SSKI)." | 5.27 | Comparative effects of sodium ipodate and iodide on serum thyroid hormone concentrations in patients with Graves' disease. ( Barlli, AL; Braverman, LE; D'Amato, L; Gardini, E; Gnudi, A; Manfredi, A; Montermini, M; Robuschi, G; Roti, E; Salvi, M, 1985) |
| "Consecutive patients with hyperthyroidism caused by Graves' disease or by multinodular toxic goiter were randomized to be treated with high-dose propylthiouracil (PTU) to block D1, PTU plus KI, or PTU plus sodium ipodate to additionally block D2." | 5.12 | Sources of circulating 3,5,3'-triiodothyronine in hyperthyroidism estimated after blocking of type 1 and type 2 iodothyronine deiodinases. ( Christensen, SE; Helleberg, K; Laurberg, P; Nielsen, S; Pedersen, KM; Seefeldt, T; Vestergaard, H, 2007) |
| "We describe the effect of administration of repeated doses of sodium ipodate in a newborn infant with hyperthyroidism due to transient Graves' disease." | 3.67 | Treatment of neonatal hyperthyroidism due to Graves' disease with sodium ipodate. ( Filetti, S; Fisher, DA; Karpman, BA; Rapoport, B, 1987) |
| "A dose (3 g) of sodium ipodate used routinely in oral cholecystography caused a fall in serum 3,5,3'-triiodothyronine and a rise in serum 3,3',5'-triiodothyronine in three patients taking thyroxine (T4), four euthyroid subjects,and four hyperthyroid patients." | 3.66 | Changes in circulating iodothyronines in euthyroid and hyperthyroid subjects given ipodate (Oragrafin), an agent for oral cholecystography. ( Bennett, LR; Chopra, IJ; Solomon, DH; Wu, SY, 1978) |
| "No ipodate was discontinued in the eight patients who did not respond, and they were then treated with MMI." | 1.29 | Sodium ipodate and methimazole in the long-term treatment of hyperthyroid Graves' disease. ( Bianconi, L; Braverman, LE; Gardini, E; Minelli, R; Roti, E, 1993) |
| " Its advantages over conventional therapy are a rapid fall in thyroid hormones and control of symptoms with a simple dosage regime." | 1.28 | Resistant hyperthyroidism induced by sodium iopodate used as treatment for Graves' disease. ( Caldwell, G; Errington, M; Toft, AD, 1989) |
| "Patients with thyrotoxic Graves' disease were treated daily for 10 d with 1 g sodium ipodate, an iodine rich X-ray contrast agent which impairs outer ring (5'-) deiodination of T4 to T3, or with 12 drops of a saturated solution of potassium iodide (SSKI)." | 1.27 | Comparative effects of sodium ipodate and iodide on serum thyroid hormone concentrations in patients with Graves' disease. ( Barlli, AL; Braverman, LE; D'Amato, L; Gardini, E; Gnudi, A; Manfredi, A; Montermini, M; Robuschi, G; Roti, E; Salvi, M, 1985) |
| " We conclude that 1) ipodate (500 mg daily) reduces serum T4 and T3 levels as fast and as much as does the 1-g daily dose studied previously; 2) long term use (for 23-31 weeks) of ipodate for the treatment of Graves' hyperthyroidism is clinically feasible; no adverse effects occurred during or after ipodate treatment; and 3) RAI uptake returns to pretreatment levels as early as 7 days after the discontinuation of ipodate." | 1.27 | Long term treatment of Graves' hyperthyroidism with sodium ipodate. ( Bian, TY; Chopra, IJ; Huang, HW; Jeng, CY; Shen, DC; Shian, LR; Solomon, DH; Wu, SY, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (63.16) | 18.7374 |
| 1990's | 6 (31.58) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laurberg, P | 1 |
| Vestergaard, H | 1 |
| Nielsen, S | 1 |
| Christensen, SE | 1 |
| Seefeldt, T | 1 |
| Helleberg, K | 1 |
| Pedersen, KM | 1 |
| Arteaga, E | 1 |
| López, JM | 1 |
| Rodríguez, JA | 1 |
| Michaud, P | 1 |
| López, G | 1 |
| Sharp, B | 1 |
| Reed, AW | 1 |
| Tamagra, EI | 1 |
| Geffner, DL | 1 |
| Hershman, JM | 1 |
| Wu, SY | 6 |
| Shyh, TP | 1 |
| Chopra, IJ | 5 |
| Solomon, DH | 5 |
| Huang, HW | 2 |
| Chu, PC | 1 |
| Joshi, R | 1 |
| Kulin, HE | 1 |
| Roti, E | 4 |
| Gardini, E | 4 |
| Minelli, R | 1 |
| Bianconi, L | 1 |
| Braverman, LE | 4 |
| Tomaski, SM | 1 |
| Mahoney, EM | 1 |
| Burgess, LP | 1 |
| Raines, KB | 1 |
| Bornemann, M | 1 |
| Johnson, DE | 1 |
| Bennett, LR | 1 |
| Huang, WS | 1 |
| Polk, D | 1 |
| Florsheim, WH | 1 |
| Green, WL | 1 |
| Fisher, DA | 2 |
| Martino, E | 1 |
| Balzano, S | 1 |
| Bartalena, L | 1 |
| Loviselli, A | 1 |
| Sica, V | 1 |
| Petrini, L | 1 |
| Grasso, L | 1 |
| Piga, M | 1 |
| Shen, DC | 2 |
| Shian, LR | 2 |
| Florsheim, W | 1 |
| Berghout, A | 1 |
| Wiersinga, WM | 1 |
| Brummelkamp, WH | 1 |
| Caldwell, G | 1 |
| Errington, M | 1 |
| Toft, AD | 1 |
| Robuschi, G | 3 |
| Montermini, M | 3 |
| Salvi, M | 3 |
| Manfredi, A | 3 |
| Gnudi, A | 3 |
| d'Amato, L | 2 |
| Borciani, E | 1 |
| Negrotti, L | 1 |
| Karpman, BA | 1 |
| Rapoport, B | 1 |
| Filetti, S | 1 |
| Barlli, AL | 1 |
| Bian, TY | 1 |
| Jeng, CY | 1 |
5 trials available for ipodate and Basedow Disease
| Article | Year |
|---|---|
Sources of circulating 3,5,3'-triiodothyronine in hyperthyroidism estimated after blocking of type 1 and type 2 iodothyronine deiodinases.
Topics: Adolescent; Adult; Antithyroid Agents; Child; Drug Therapy, Combination; Female; Goiter, Nodular; Gr | 2007 |
Therapy of Graves' disease with sodium ipodate is associated with a high recurrence rate of hyperthyroidism.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Autoantibodies; Female; Graves Disease; Humans; Immun | 1991 |
Further studies on the long-term treatment of Graves' hyperthyroidism with ipodate: assessment of a minimal effective dose.
Topics: Adult; Dose-Response Relationship, Drug; Female; Graves Disease; Humans; Hyperthyroidism; Ipodate; M | 1991 |
Comparison of methimazole, methimazole and sodium ipodate, and methimazole and saturated solution of potassium iodide in the early treatment of hyperthyroid Graves' disease.
Topics: Adult; Blood Pressure; Drug Evaluation; Drug Therapy, Combination; Female; Graves Disease; Heart Rat | 1988 |
Effect of sodium ipodate and iodide on free T4 and free T3 concentrations in patients with Graves' disease.
Topics: Adult; Clinical Trials as Topic; Female; Graves Disease; Humans; Ipodate; Male; Middle Aged; Potassi | 1986 |
14 other studies available for ipodate and Basedow Disease
| Article | Year |
|---|---|
Effect of the combination of dexamethasone and sodium ipodate on serum thyroid hormones in Graves' disease.
Topics: Adolescent; Adult; Dexamethasone; Drug Therapy, Combination; Female; Graves Disease; Humans; Ipodate | 1983 |
Treatment of hyperthyroidism with sodium ipodate (oragrafin) in addition to propylthiouracil and propranolol.
Topics: Female; Graves Disease; Humans; Ipodate; Kinetics; Male; Propranolol; Propylthiouracil; Thyroxine; T | 1981 |
Comparison sodium ipodate (oragrafin) and propylthiouracil in early treatment of hyperthyroidism.
Topics: Adult; Blood Pressure; Body Weight; Female; Graves Disease; Humans; Ipodate; Kinetics; Male; Middle | 1982 |
Treatment of neonatal Graves' disease with sodium ipodate. A case report.
Topics: Drug Therapy, Combination; Graves Disease; Humans; Infant, Newborn; Infant, Premature, Diseases; Ipo | 1993 |
Sodium ipodate and methimazole in the long-term treatment of hyperthyroid Graves' disease.
Topics: Adult; Autoantibodies; Body Weight; Female; Graves Disease; Heart Rate; Humans; Ipodate; Male; Methi | 1993 |
Sodium ipodate (oragrafin) in the preoperative preparation of Graves' hyperthyroidism.
Topics: Adrenergic beta-Antagonists; Adult; Antithyroid Agents; Blood Loss, Surgical; Female; Graves Disease | 1997 |
The effect of repeated administration of ipodate (Oragrafin) in hyperthyroidism.
Topics: Adolescent; Adult; Body Weight; Drug Evaluation; Female; Graves Disease; Humans; Ipodate; Male; Midd | 1978 |
Changes in circulating iodothyronines in euthyroid and hyperthyroid subjects given ipodate (Oragrafin), an agent for oral cholecystography.
Topics: Graves Disease; Humans; Hyperthyroidism; Ipodate; Kinetics; Male; Reference Values; Thyroiditis, Aut | 1978 |
Identification of thyroxine-sulfate (T4S) in human serum and amniotic fluid by a novel T4S radioimmunoassay.
Topics: Amniotic Fluid; Analysis of Variance; Female; Graves Disease; Humans; Ipodate; Pregnancy; Propylthio | 1992 |
Sodium ipodate in the preparation of Graves' hyperthyroid patients for thyroidectomy.
Topics: Adult; Body Weight; Female; Graves Disease; Humans; Ipodate; Male; Middle Aged; Preanesthetic Medica | 1989 |
Resistant hyperthyroidism induced by sodium iopodate used as treatment for Graves' disease.
Topics: Adult; Female; Graves Disease; Humans; Hyperthyroidism; Ipodate; Time Factors | 1989 |
Treatment of neonatal hyperthyroidism due to Graves' disease with sodium ipodate.
Topics: Antibodies; Female; Graves Disease; Humans; Hyperthyroidism; Infant, Newborn; Ipodate; Thyroid Gland | 1987 |
Comparative effects of sodium ipodate and iodide on serum thyroid hormone concentrations in patients with Graves' disease.
Topics: Adult; Female; Graves Disease; Humans; Ipodate; Male; Potassium Iodide; Thyroid Hormones; Thyroxine; | 1985 |
Long term treatment of Graves' hyperthyroidism with sodium ipodate.
Topics: Adult; Female; Graves Disease; Humans; Ipodate; Long-Term Care; Male; Middle Aged; Thyroxine; Triiod | 1985 |