Page last updated: 2024-10-29

ioxaglate and Pain

ioxaglate has been researched along with Pain in 25 studies

Ioxaglic Acid: A low-osmolar, ionic contrast medium used in various radiographic procedures.
ioxaglic acid : A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an acetyl(methyl)amino group at the 5-position.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"The degree of albuminuria induced by renal arteriography with the monoacid dimeric contrast medium ioxaglate was studied in 19 patients."7.66Subjective responses and albuminuria induced by ioxaglate during renal angiography in man. ( Holtås, SL; Nilsson, PE; Tejler, LT, 1982)
"Two low-osmolality contrast agents, ioxaglate meglumine/sodium and iohexol were compared with diatrizoate meglumine/sodium in a controlled double blind study of 126 patients undergoing arteriography for peripheral vascular disease to determine which caused the least pain."5.06Pain in peripheral arteriography: an assessment of conventional versus ionic and non-ionic low-osmolality contrast agents. ( Campbell, DR; Fraser, DB; Murphy, G, 1988)
"The degree of albuminuria induced by renal arteriography with the monoacid dimeric contrast medium ioxaglate was studied in 19 patients."3.66Subjective responses and albuminuria induced by ioxaglate during renal angiography in man. ( Holtås, SL; Nilsson, PE; Tejler, LT, 1982)
"Heat and pain were scored on visual analog scales."2.68Iohexol vs. ioxaglate in lower extremity angiography: a comparative randomized double-blind study in 80 patients. ( Guit, GL; Krouwels, MM; Overbosch, EH, 1996)
"17 patients had indirect inguinal hernias and 7 had direct inguinal hernias (which are claimed to be extremely rare in women)."1.30Herniography in women under 40 years old with chronic groin pain. ( Ekberg, O; Kesek, P, 1999)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199020 (80.00)18.7374
1990's4 (16.00)18.2507
2000's1 (4.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Valk, J1
Crezée, F1
Olislagers-de Slegte, RG1
Sacks, BA1
Ellison, HP1
Bartek, S1
Vine, HS1
Palestrant, AM1
Kumazaki, T2
Hosoi, S1
Sugawara, K1
Honda, K1
Hagen, B2
Clauss, W1
Heystraten, FM1
van den Berg, FG1
Mulderije, ED1
Meijenhorst, GC1
de Bruin, JN1
Nilsson, PE2
Holtås, SL1
Tejler, LT1
Nyman, U1
Nilsson, P1
Westergren, A1
Schütte, HE1
Straub, H1
Wiebe, V1
Jensen, KK1
Freiberg, H1
Erikson, U1
Hemmingsson, A1
Moreau, JF1
Dana, A1
Sterin, P1
Schmit, P1
Michel, JR1
Krouwels, MM1
Overbosch, EH1
Guit, GL1
Kesek, P1
Ekberg, O2
Gerber, SL1
Duprat, G1
Schmitt, HE1
Da Silva, A1
Gomi, N1
Lindequist, S1
Justesen, P1
Larsen, C1
Rasmussen, F1
Pathria, M1
Somers, S1
Gill, G1
Murphy, G1
Campbell, DR1
Fraser, DB1
Kokubo, T1
Iio, M1
Hiramatsu, K1
Takamiya, M1
Yamada, R1
Takahashi, M1
Katzberg, RW1
Miller, TL1
Hayakawa, K1
Manzione, JV1
Tallents, RH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Can Contrast Infused Sonography Using Air Bubbles Replace Hysterosalpingogram as the Diagnostic Evaluation of Fallopian Tube Patency Following Hysteroscopic Sterilization Using Essure[NCT02628873]21 participants (Actual)Interventional2015-12-31Terminated (stopped due to Essure no longer sold in the US after Dec 2018; Sponsor requested trial be ended)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Physician Evaluation of Uterine Cavity

"Observed image of uterus (normal or not normal). Assessor commented on uterine cavity to determine whether cavity was normal versus abnormal, e.g., bicornuate uterus or any notable uterine deformity. Data were coded as normal' or not normal." (NCT02628873)
Timeframe: At time of HyCoSy procedure

InterventionParticipants (Count of Participants)
Arm 1 (HyCoSy Followed by HSG)13
Arm 2 (HSG Followed by HyCoSy)6

Fallopian Tube Patency - HyCoSy vs HSG

Observed flow of fluid/bubbles through fallopian tubes. (NCT02628873)
Timeframe: At time of procedure

,
Interventionfallopian tubes observed to be closed (Count of Units)
Number of tubes closed per first procedureNumber of tubes closed per second procedure
Arm 1 (HyCoSy Followed by HSG)2425
Arm 2 (HSG Followed by HyCoSy)1212

Pain Scores

Patient reported pain scale score on visual pain scale (rated 0 for no pain to 10 for severe pain with corresponding faces) (NCT02628873)
Timeframe: At time of procedures

,
Interventionunits on a scale (Mean)
HSG post procedure pain scoreHyCoSy post procedure pain score
Arm 1 (HyCoSy Followed by HSG)1.42.4
Arm 2 (HSG Followed by HyCoSy)1.82.3

Trials

13 trials available for ioxaglate and Pain

ArticleYear
Comparison of iohexol 300 mg I/ml and Hexabrix 320 mg I/ml in central angiography. A double-blind trial.
    Neuroradiology, 1984, Volume: 26, Issue:3

    Topics: Adult; Blood Pressure; Cerebral Angiography; Clinical Trials as Topic; Contrast Media; Double-Blind

1984
A comparison of hexabrix and Renografin 60 in peripheral arteriography.
    AJR. American journal of roentgenology, 1983, Volume: 140, Issue:5

    Topics: Angiography; Arterial Occlusive Diseases; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Double

1983
[Contrast media and pain in peripheral arteriography. Randomized, intra-individual double-blind trial: ioglicinate, ioglicinate-lidocaine, ioxaglate].
    Der Radiologe, 1982, Volume: 22, Issue:10

    Topics: Angiography; Arterial Occlusive Diseases; Clinical Trials as Topic; Contrast Media; Double-Blind Met

1982
Comparison of pain and heat sensation of contrast media in aortofemoral angiography: meglumine-amidotrizoate (Angiografin) mixed with lidocaine versus sodium-meglumine-ioxaglate (Hexabrix).
    Diagnostic imaging, 1983, Volume: 52, Issue:2-3

    Topics: Aortography; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Double-Blind Method; Female; Humans

1983
Hexabrix (ioxaglate), a new low osmolality contrast agent for lumbar epidural double-catheter venography.
    Neuroradiology, 1980, Volume: 20, Issue:1

    Topics: Clinical Trials as Topic; Contrast Media; Epidural Space; Humans; Iliac Vein; Intervertebral Disc Di

1980
Pain and hemodynamic effects in aortofemoral angiography. Clinical comparison of iohexol, ioxaglate and metrizamide.
    Acta radiologica: diagnosis, 1982, Volume: 23, Issue:4

    Topics: Aged; Aortography; Blood Pressure; Contrast Media; Female; Femoral Artery; Heart Rate; Hemodynamics;

1982
Experiences with ioxaglate (Hexabrix) in cardioangiography and peripheral angiography.
    Acta radiologica: diagnosis, 1981, Volume: 22, Issue:6

    Topics: Angiocardiography; Angiography; Aortography; Blood Pressure; Diatrizoate Meglumine; Female; Heart Ra

1981
Iohexol vs. ioxaglate in lower extremity angiography: a comparative randomized double-blind study in 80 patients.
    European journal of radiology, 1996, Volume: 22, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Angiography; Contrast Media; Double-Blind Method; Female; Humans; Io

1996
Diagnostic quality and complications of hysterosalpingography: oil- versus water-soluble contrast media--a randomized prospective study.
    Radiology, 1991, Volume: 179, Issue:1

    Topics: Contrast Media; Diatrizoate Meglumine; Ethiodized Oil; Extravasation of Diagnostic and Therapeutic M

1991
Pain during angiography: a randomized double-blind trial comparing ioxaglate and diatrizoate.
    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 1987, Volume: 38, Issue:1

    Topics: Adult; Aged; Angiography; Clinical Trials as Topic; Diatrizoate; Diatrizoate Meglumine; Double-Blind

1987
Pain in peripheral arteriography: an assessment of conventional versus ionic and non-ionic low-osmolality contrast agents.
    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 1988, Volume: 39, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Angiography; Clinical Trials as Topic; Contrast Media; Diatrizoate M

1988
Herniography: comparison of morbidity and image quality after use of high and low osmolality contrast media.
    Investigative radiology, 1986, Volume: 21, Issue:5

    Topics: Adult; Aged; Contrast Media; Female; Hernia, Inguinal; Humans; Iodobenzoates; Ioxaglic Acid; Male; M

1986
Temporomandibular joint arthrography: comparison of morbidity with ionic and low osmolality contrast media.
    Radiology, 1985, Volume: 155, Issue:1

    Topics: Adult; Clinical Trials as Topic; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Double-Blind Me

1985

Other Studies

12 other studies available for ioxaglate and Pain

ArticleYear
Bronchial and intercostal angiography with ioxaglate and diatrizoate in man. A comparative investigation.
    Acta radiologica: diagnosis, 1984, Volume: 25, Issue:1

    Topics: Aged; Blood Pressure; Bronchial Arteries; Contrast Media; Cough; Diatrizoate; Diatrizoate Meglumine;

1984
Subjective responses and albuminuria induced by ioxaglate during renal angiography in man.
    Radiology, 1982, Volume: 144, Issue:3

    Topics: Adult; Aged; Albuminuria; Angiography; Contrast Media; Hot Temperature; Humans; Iodobenzoates; Ioxag

1982
[Iopamidol, a new non-ionic roentgen contrast medium. Results of angiographic studies in more than 300 patients, with special reference to pain reactions].
    Der Radiologe, 1982, Volume: 22, Issue:12

    Topics: Angiography; Double-Blind Method; Drug Tolerance; Hot Temperature; Humans; Iopamidol; Iothalamic Aci

1982
Comparative study: Endografine (diatrizoate), Vasurix polyvidone (acetrizoate), Dimer-X (iocarmate) and Hexabrix (ioxaglate) in hysterosalpingography.
    Diagnostic imaging, 1982, Volume: 51, Issue:6

    Topics: Abdomen; Acetrizoic Acid; Adult; Contrast Media; Diatrizoate; Female; Humans; Hysterosalpingography;

1982
[Reduction of side effects in aortofemoral angiography: low-osmolar contrast medium compared with conventional contrast medium plus local anaesthetic (author's transl)].
    Rontgen-Blatter; Zeitschrift fur Rontgen-Technik und medizinisch-wissenschaftliche Photographie, 1981, Volume: 34, Issue:4

    Topics: Aged; Aortography; Blood Pressure; Double-Blind Method; Female; Femoral Artery; Heart Rate; Hot Temp

1981
[Arteriography with ioxaglate (Hexabrix), a new low-osmolar contrast medium. A comparative study on amidotrizoate (Urografin-meglumine) with regard to subjective discomforts].
    Ugeskrift for laeger, 1981, Mar-15, Volume: 143, Issue:11

    Topics: Angiography; Contrast Media; Diatrizoate; Humans; Iodobenzoates; Ioxaglic Acid; Osmolar Concentratio

1981
[Painless angiography of arteriovenous shunts for hemodialysis. Value of ioxaglic acid].
    La Nouvelle presse medicale, 1980, Mar-15, Volume: 9, Issue:13

    Topics: Adult; Angiography; Arteriovenous Shunt, Surgical; Contrast Media; Humans; Iodobenzoates; Ioxaglic A

1980
Herniography in women under 40 years old with chronic groin pain.
    The European journal of surgery = Acta chirurgica, 1999, Volume: 165, Issue:6

    Topics: Adolescent; Adult; Chronic Disease; Contrast Media; Female; Hernia, Inguinal; Humans; Ioxaglic Acid;

1999
Orbital compression syndrome after orbital extravasation of X-ray contrast material.
    American journal of ophthalmology, 2000, Volume: 130, Issue:4

    Topics: Compartment Syndromes; Contrast Media; Exophthalmos; Extravasation of Diagnostic and Therapeutic Mat

2000
[About pain during peripheral arteriography].
    VASA. Zeitschrift fur Gefasskrankheiten, 1979, Volume: 8, Issue:4

    Topics: Adult; Aged; Aortography; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Female; Humans; Ioxagl

1979
Vasoconstriction by angiographic contrast media in isolated canine arteries.
    The British journal of radiology, 1992, Volume: 65, Issue:779

    Topics: Animals; Arteries; Contrast Media; Diatrizoate; Dogs; Female; Iopamidol; Ioxaglic Acid; Male; Mannit

1992
[Clinical usefulness of ioxaglate (isotonic contrast material, ER-61) in digital subtraction angiography].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1988, Jan-25, Volume: 48, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiography; Child; Female; Humans; Ioxaglic Acid; Male;

1988