Page last updated: 2024-10-29

ioxaglate and Kidney Diseases

ioxaglate has been researched along with Kidney Diseases in 20 studies

Ioxaglic Acid: A low-osmolar, ionic contrast medium used in various radiographic procedures.
ioxaglic acid : A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an acetyl(methyl)amino group at the 5-position.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
" Gentamicin (GE) acts mainly in proximal tubular cells, where it is uptake via organic anion transport system and it induces a high incidence of nephrotoxicity, which is characterized by tubular necrosis [5] leading to acute renal failure in 10 to 50% of patients."3.71Effects of gentamicin, lipopolysaccharide, and contrast media on immortalized proximal tubular cells. ( Cunha, MA; Schor, N, 2002)
"Nephrotoxicity of radio-opaque contrast media (CM) is generally believed to involve toxic injury of proximal tubular cells."2.66Nephrotoxicity of high- and low-osmolality contrast media. ( Avila, A; Dennis, B; Finnie, KJ; Jevnikar, AM; Linton, AL; Plummer, DT, 1988)
"Ozone treatment was applied for 5 days after the contrast agent was introduced in Group V."1.48An experimental study on the preventive effects of N-acetyl cysteine and ozone treatment against contrast-induced nephropathy. ( Adali, Y; Eroglu, HA; Kuzucu, M; Ozturk, O; Ustebay, S, 2018)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19904 (20.00)18.7374
1990's2 (10.00)18.2507
2000's9 (45.00)29.6817
2010's4 (20.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Freitas, RAP1
Tanajura, LF1
Mehran, R3
Chamié, D1
Chaves, A1
Centemero, M1
Braga, S1
Costa, R1
Cao, D1
Sousa, A1
Feres, F1
Costa, JR1
Ozturk, O1
Eroglu, HA1
Ustebay, S1
Kuzucu, M1
Adali, Y1
Nikolsky, E2
Kirtane, AJ1
Caixeta, A1
Wong, SC1
Teirstein, PS1
Downey, WE1
Batchelor, WB1
Casterella, PJ1
Kim, YH1
Fahy, M1
Dangas, GD1
Reed, M1
Meier, P1
Tamhane, UU1
Welch, KB1
Moscucci, M1
Gurm, HS1
Angoulvant, D1
Cucherat, M1
Rioufol, G1
Finet, G1
Beaune, J1
Revel, D1
Laville, M1
Ovize, M1
André-Fouët, X1
Sendeski, M1
Patzak, A1
Persson, PB1
Barlak, A1
Akar, H1
Yenicerioglu, Y1
Yenisey, C1
Meteoğlu, I1
Yilmaz, O1
Aslanger, E1
Uslu, B1
Akdeniz, C1
Polat, N1
Cizgici, Y1
Oflaz, H1
Cunha, MA1
Schor, N1
Dangas, G1
Iakovou, I1
Aymong, ED1
Mintz, GS1
Kipshidze, NN1
Lansky, AJ1
Moussa, I1
Stone, GW1
Moses, JW1
Leon, MB1
Gomes, VO1
Poli de Figueredo, CE1
Caramori, P1
Lasevitch, R1
Bodanese, LC1
Araújo, A1
Röedel, AP1
Caramori, AP1
Brito, FS1
Bezerra, HG1
Nery, P1
Brizolara, A1
Dussol, B1
Morange, S1
Loundoun, A1
Auquier, P1
Berland, Y1
Reed, PS1
Dixon, SR1
Boura, JA1
O'Neill, WW1
Kahn, JK1
Jo, SH1
Koo, BK1
Youn, TJ1
Kim, HS1
Heep, HW1
Müller-Lüdecke, H1
Reither, M1
Klingmüller, V1
Vlietstra, RE1
Nunn, CM1
Narvarte, J1
Browne, KF1
Ogle, GD1
Swinburn, MJ1
McCredie, RM1
Hoogewoud, HM1
Petropoulos, P1
Jevnikar, AM1
Finnie, KJ1
Dennis, B1
Plummer, DT1
Avila, A1
Linton, AL1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Benefit of Transradial Approach in Chronic Kidney Disease Population Undergoing Cardiac Catheterization, A Single Center Randomized Controlled Trial[NCT02933892]Phase 4100 participants (Anticipated)Interventional2016-10-31Recruiting
Efficacy of Oral Sodium Chloride vs iv Sodium Chloride in the Prevention of Contrast Nephropathy in Outpatients[NCT03476460]Phase 2269 participants (Actual)Interventional2014-03-01Completed
Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease (ENRICH): A Randomized Controlled Trial[NCT05283512]254 participants (Anticipated)Interventional2022-04-20Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ioxaglate and Kidney Diseases

ArticleYear
The relative renal safety of iodixanol compared with low-osmolar contrast media: a meta-analysis of randomized controlled trials.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:7

    Topics: Aged; Aged, 80 and over; Consumer Product Safety; Contrast Media; Evidence-Based Medicine; Female; H

2009

Trials

9 trials available for ioxaglate and Kidney Diseases

ArticleYear
Ioxaglate Versus IoDixanol for the Prevention of Contrast-Induced Nephropathy: The IDPC Trial.
    The Journal of invasive cardiology, 2023, Volume: 35, Issue:6

    Topics: Aged; Contrast Media; Coronary Angiography; Creatinine; Humans; Ioxaglic Acid; Kidney Diseases; Risk

2023
Ionic low-osmolar versus nonionic iso-osmolar contrast media to obviate worsening nephropathy after angioplasty in chronic renal failure patients: the ICON (Ionic versus non-ionic Contrast to Obviate worsening Nephropathy after angioplasty in chronic rena
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:5

    Topics: Aged; Angioplasty, Balloon; Contrast Media; Coronary Angiography; Coronary Artery Disease; Creatinin

2009
Preventing acute decrease in renal function induced by coronary angiography (PRECORD): a prospective randomized trial.
    Archives of cardiovascular diseases, 2009, Volume: 102, Issue:11

    Topics: Acute Disease; Biomarkers; Contrast Media; Coronary Angiography; Creatinine; Female; Fluid Therapy;

2009
Intrarenal application of N-acetylcysteine for the prevention of contrast medium-induced nephropathy in primary angioplasty.
    Coronary artery disease, 2012, Volume: 23, Issue:4

    Topics: Acetylcysteine; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Female;

2012
N-acetylcysteine does not prevent contrast induced nephropathy after cardiac catheterisation with an ionic low osmolality contrast medium: a multicentre clinical trial.
    Heart (British Cardiac Society), 2005, Volume: 91, Issue:6

    Topics: Acetylcysteine; Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Cardiac Catheterization;

2005
A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:8

    Topics: Administration, Oral; Aged; Contrast Media; Creatinine; Diabetic Nephropathies; Diuretics; Drug Syne

2006
A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:8

    Topics: Administration, Oral; Aged; Contrast Media; Creatinine; Diabetic Nephropathies; Diuretics; Drug Syne

2006
A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:8

    Topics: Administration, Oral; Aged; Contrast Media; Creatinine; Diabetic Nephropathies; Diuretics; Drug Syne

2006
A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:8

    Topics: Administration, Oral; Aged; Contrast Media; Creatinine; Diabetic Nephropathies; Diuretics; Drug Syne

2006
[Use of hypo-osmolar contrast media in urography--results of an interindividual, randomized double-blind study].
    Rontgenpraxis; Zeitschrift fur radiologische Technik, 1984, Volume: 37, Issue:6

    Topics: Adult; Aged; Clinical Trials as Topic; Contrast Media; Double-Blind Method; Female; Humans; Iodobenz

1984
[Initial trials using Hexabrix in excretory urography in childhood].
    Fortschritte der Medizin, 1981, May-28, Volume: 99, Issue:20

    Topics: Child; Child, Preschool; Contrast Media; Diagnosis, Differential; Humans; Infant; Iodobenzoates; Iox

1981
Nephrotoxicity of high- and low-osmolality contrast media.
    Nephron, 1988, Volume: 48, Issue:4

    Topics: Adult; Aged; Contrast Media; Coronary Angiography; Diatrizoate; Female; Humans; Iohexol; Ioxaglic Ac

1988

Other Studies

10 other studies available for ioxaglate and Kidney Diseases

ArticleYear
An experimental study on the preventive effects of N-acetyl cysteine and ozone treatment against contrast-induced nephropathy.
    Acta cirurgica brasileira, 2018, Volume: 33, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Contrast Media; Creatinine; Ioxaglic Acid; Kidney; Kidney Dis

2018
Constriction of the vasa recta, the vessels supplying the area at risk for acute kidney injury, by four different iodinated contrast media, evaluating ionic, nonionic, monomeric and dimeric agents.
    Investigative radiology, 2010, Volume: 45, Issue:8

    Topics: Analysis of Variance; Angiotensin II; Animals; Contrast Media; Diatrizoate; Humans; Iohexol; Ioxagli

2010
Effect of sodium bicarbonate in an experimental model of radiocontrast nephropathy.
    Renal failure, 2010, Volume: 32, Issue:8

    Topics: Animals; Contrast Media; Disease Models, Animal; Female; Infusions, Intravenous; Ioxaglic Acid; Kidn

2010
Effects of gentamicin, lipopolysaccharide, and contrast media on immortalized proximal tubular cells.
    Renal failure, 2002, Volume: 24, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Apoptosis; Calcium; Contrast Media; Disease Models, Animal; Gentamic

2002
Contrast-induced nephropathy after percutaneous coronary interventions in relation to chronic kidney disease and hemodynamic variables.
    The American journal of cardiology, 2005, Jan-01, Volume: 95, Issue:1

    Topics: Aged; Chronic Disease; Contrast Media; Coronary Disease; Female; Follow-Up Studies; Hemodynamics; Hu

2005
Comparison of the usefulness of gadodiamide and iodine mixture versus iodinated contrast alone for prevention of contrast-induced nephropathy in patients with chronic kidney disease undergoing coronary angiography.
    The American journal of cardiology, 2007, Oct-01, Volume: 100, Issue:7

    Topics: Aged; Aged, 80 and over; Chronic Disease; Contrast Media; Coronary Angiography; Female; Gadolinium D

2007
Conclusion of recent 'osmolality trials' in preventing contrast-induced nephropathy by NAC--what is the standard?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:7

    Topics: Angiography; Contrast Media; Cystatin C; Cystatins; Glomerular Filtration Rate; Humans; Iohexol; Iox

2008
Contrast nephropathy after coronary angioplasty in chronic renal insufficiency.
    American heart journal, 1996, Volume: 132, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Disease; Cr

1996
Ioxaglate in paediatric angiocardiography.
    Journal of paediatrics and child health, 1991, Volume: 27, Issue:5

    Topics: Adolescent; Angiocardiography; Child; Child, Preschool; Drug Evaluation; Female; Humans; Infant; Inf

1991
Renal embolization: a study of the interaction of contrast media and ethanol.
    Cardiovascular and interventional radiology, 1987, Volume: 10, Issue:4

    Topics: Aged; Drug Interactions; Embolization, Therapeutic; Ethanol; Humans; Iohexol; Iopamidol; Ioxaglic Ac

1987