Page last updated: 2024-10-29

ioxaglate and Hemolysis

ioxaglate has been researched along with Hemolysis in 4 studies

Ioxaglic Acid: A low-osmolar, ionic contrast medium used in various radiographic procedures.
ioxaglic acid : A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an acetyl(methyl)amino group at the 5-position.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Krause, W1
Niehues, D1
Mikkonen, R1
Lehto, T1
Koistinen, V1
Aronen, HJ1
Kivisaari, L1
Meri, S1
Hayakawa, K1
Nakamura, T1
Shimizu, Y1
Brezinski, M1
Saunders, K1
Jesser, C1
Li, X1
Fujimoto, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Optical Imaging Measurement of Intravascular Solution Efficacy Trial[NCT01743872]23 participants (Actual)Interventional2012-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Quality of Images

The metric of image quality was the clear imaging field (CIF), which was defined as a cross section in which ≥270° of the vessel wall architecture was visualized. This has been used previously to quantify adequacy of clearance in OCT image comparison. Two independent observers, blinded to the flush medium used, analyzed all OCT frames in each pullback sequence. Any disagreement >10% was resolved with a consensus re-evaluation at a later time point by the same reviewers. Each individual cross section was assigned a designation of quality or insufficient quality; thus, a quality image proportion was generated for each run by taking the mean of each observer's determinations (NCT01743872)
Timeframe: 1 month

InterventionClear imaging field (CIF) proportion (Mean)
Contrast Injection.702
Dextran Injection.872
CO2 Injection.10
Heparinized Saline.743

Superficial Femoral Artery Plaque Composition by Flush Medium

(NCT01743872)
Timeframe: 1 month

,,,
Interventionpercentage of plaque composition (Number)
Fibrotic, %Calcific, %Lipid, %Normal, %
Contrast Injection57.96.99.124.4
Dextran Injection62.15.56.325.6
Heparinized Saline63.05.46.522.9
Overall61.06.07.324.3

Other Studies

4 other studies available for ioxaglate and Hemolysis

ArticleYear
Biochemical characterization of x-ray contrast media.
    Investigative radiology, 1996, Volume: 31, Issue:1

    Topics: 1-Butanol; Animals; Biochemical Phenomena; Biochemistry; Butanols; Chemical Precipitation; Complemen

1996
Suppression of alternative complement pathway activity by radiographic contrast media.
    Scandinavian journal of immunology, 1997, Volume: 45, Issue:4

    Topics: Complement C3-C5 Convertases; Complement C3a; Complement C3b; Complement Factor B; Complement Factor

1997
Role of hemolysis in potassium release by iodinated contrast medium.
    European radiology, 1999, Volume: 9, Issue:7

    Topics: Aged; Aged, 80 and over; Angiography; Contrast Media; Diatrizoate Meglumine; Female; Haptoglobins; H

1999
Index matching to improve optical coherence tomography imaging through blood.
    Circulation, 2001, Apr-17, Volume: 103, Issue:15

    Topics: Blood; Blood Flow Velocity; Blood Physiological Phenomena; Contrast Media; Coronary Disease; Dextran

2001