ioxaglate has been researched along with Coronary Heart Disease in 43 studies
Ioxaglic Acid: A low-osmolar, ionic contrast medium used in various radiographic procedures.
ioxaglic acid : A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an acetyl(methyl)amino group at the 5-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The acute effects of diltiazem on coronary reactive hyperemia were studied in 12 patients with flow-limiting coronary stenosis." | 7.67 | Effect of diltiazem on coronary reactive hyperemia in patients with flow-limiting coronary artery stenosis. ( Blanchet, F; Foult, JM; Nitenberg, A; Zouiouèche, S, 1986) |
| "A contrast medium-induced coronary reactive hyperemia (HPR) evidenced an increased hyperemic volume from 9." | 5.27 | Alterations in contrast medium-induced coronary reactive hyperemia after bepridil in patients with coronary artery disease. ( Blanchet, F; Foult, JM; Huyghebaert, MF; Nitenberg, A; Zouiouèche, S, 1985) |
| "The incidence of cardiac arrhythmias in patients with coronary artery disease receiving intravenous contrast medium has been studied and comparison made between a conventional ionic medium (meglumine iothalamate) and a low osmolar medium (sodium meglumine ioxaglate)." | 5.06 | A comparison of the incidence of cardiac arrhythmias produced by two intravenous contrast media in coronary artery disease. ( Foster, CJ; Griffin, JF, 1987) |
| "The acute effects of diltiazem on coronary reactive hyperemia were studied in 12 patients with flow-limiting coronary stenosis." | 3.67 | Effect of diltiazem on coronary reactive hyperemia in patients with flow-limiting coronary artery stenosis. ( Blanchet, F; Foult, JM; Nitenberg, A; Zouiouèche, S, 1986) |
| "In eighty patients with different cardiac diseases the theoretically claimed reduced cardiovascular side effects in ionic and non-ionic low osmolar contrast media compared to those in conventional ionic and high-osmolar contrast media were tested during heart catheterization." | 2.65 | [Early hemodynamic reactions of an ionic low osmolar and a nonionic contrast medium]. ( Heinrich, R; Wink, K, 1984) |
| "Anti-ioxaglate IgE-RIA was positive in only one patient from group 1." | 1.31 | The increased histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by specific IgE. ( Aimone-Gastin, I; Amoghly, F; Bellou, A; Danchin, N; Faure, G; Gérard, P; Guéant, JL; Jullière, Y; Rodriguez, RM; Romano, A, 2002) |
| "Ioxaglate did not cause any major adverse effects; side effects were rare and mild." | 1.27 | Clinical experience with ioxaglate (Hexabrix) in selective coronary arteriography. ( Bonan, R; Bourassa, MG; Corcos, T; David, PR; Lespérance, J; Paquet, E, 1984) |
| "A contrast medium-induced coronary reactive hyperemia (HPR) evidenced an increased hyperemic volume from 9." | 1.27 | Alterations in contrast medium-induced coronary reactive hyperemia after bepridil in patients with coronary artery disease. ( Blanchet, F; Foult, JM; Huyghebaert, MF; Nitenberg, A; Zouiouèche, S, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (48.84) | 18.7374 |
| 1990's | 14 (32.56) | 18.2507 |
| 2000's | 8 (18.60) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rodriguez, RM | 1 |
| Guéant, JL | 1 |
| Aimone-Gastin, I | 1 |
| Gérard, P | 1 |
| Amoghly, F | 1 |
| Bellou, A | 1 |
| Jullière, Y | 1 |
| Faure, G | 1 |
| Danchin, N | 1 |
| Romano, A | 1 |
| Esplugas, E | 2 |
| Cequier, A | 1 |
| Gomez-Hospital, JA | 1 |
| Del Blanco, BG | 1 |
| Jara, F | 2 |
| Danzi, GB | 1 |
| Capuano, C | 1 |
| Sesana, M | 1 |
| Predolini, S | 1 |
| Baglini, R | 1 |
| Dangas, G | 1 |
| Iakovou, I | 1 |
| Nikolsky, E | 1 |
| Aymong, ED | 1 |
| Mintz, GS | 1 |
| Kipshidze, NN | 1 |
| Lansky, AJ | 1 |
| Moussa, I | 1 |
| Stone, GW | 1 |
| Moses, JW | 1 |
| Leon, MB | 1 |
| Mehran, R | 1 |
| Deray, G | 1 |
| Persson, P | 1 |
| Liss, P | 1 |
| Hansell, P | 1 |
| Lyons, J | 1 |
| Brooks, N | 1 |
| Cattell, M | 1 |
| Isolani-Smyth, E | 1 |
| Balcon, R | 1 |
| Fraser, AG | 1 |
| Culling, W | 1 |
| Singh, H | 1 |
| Ruttley, MS | 1 |
| Newcombe, RG | 1 |
| Wink, K | 1 |
| Heinrich, R | 1 |
| Corcos, T | 1 |
| David, PR | 1 |
| Bonan, R | 1 |
| Paquet, E | 1 |
| Lespérance, J | 1 |
| Bourassa, MG | 1 |
| Dübel, HP | 1 |
| Tschapek, A | 1 |
| Crochet, D | 1 |
| Petitier, H | 2 |
| de Laguerenne, J | 1 |
| Wanlin, P | 1 |
| Bourdon, A | 1 |
| Grossetête, R | 1 |
| Bonoron-Adele, S | 1 |
| Sicart, M | 1 |
| Ohayon, J | 1 |
| Colle, JP | 1 |
| Ledain, L | 1 |
| Tariosse, L | 1 |
| Besse, P | 1 |
| Selin, K | 1 |
| Björk, L | 1 |
| Zipfel, J | 1 |
| Baller, D | 1 |
| Blanke, H | 1 |
| Karsch, KR | 1 |
| Wolpers, HG | 1 |
| Hellige, G | 1 |
| Rentrop, P | 1 |
| Tveit, K | 1 |
| Bolz, KD | 1 |
| Bolstad, B | 1 |
| Haugland, T | 1 |
| Berg, KJ | 1 |
| Skjaerpe, T | 1 |
| Kloster, YF | 1 |
| Marchese, A | 1 |
| Galiuto, L | 1 |
| Cavallari, D | 1 |
| Iliceto, S | 1 |
| Rizzon, P | 1 |
| Grabowski, EF | 2 |
| Rodriguez, M | 1 |
| McDonnell, SL | 1 |
| Piessens, JH | 1 |
| Stammen, F | 1 |
| Vrolix, MC | 1 |
| Glazier, JJ | 1 |
| Benit, E | 1 |
| De Geest, H | 1 |
| Willems, JL | 1 |
| Fransson, SG | 1 |
| Stenport, G | 1 |
| Andersson, M | 1 |
| Boor, SE | 1 |
| Rodino, LJ | 1 |
| Jang, IK | 1 |
| Gold, H | 1 |
| Michelson, AD | 1 |
| Vlietstra, RE | 2 |
| Nunn, CM | 1 |
| Narvarte, J | 1 |
| Browne, KF | 1 |
| Nishino, M | 1 |
| Tanouchi, J | 1 |
| Kawabata, M | 1 |
| Tanaka, K | 1 |
| Ito, T | 1 |
| Kato, J | 1 |
| Yamada, Y | 1 |
| Kamada, T | 1 |
| Davidson, CJ | 1 |
| Laskey, WK | 1 |
| Hermiller, JB | 1 |
| Harrison, JK | 1 |
| Matthai, W | 1 |
| Brinker, JA | 1 |
| Kereiakes, DJ | 1 |
| Muhlestein, JB | 1 |
| Lansky, A | 1 |
| Popma, JJ | 1 |
| Buchbinder, M | 1 |
| Hirshfeld, JW | 1 |
| Brezinski, M | 1 |
| Saunders, K | 1 |
| Jesser, C | 1 |
| Li, X | 1 |
| Fujimoto, J | 1 |
| Miller, RM | 1 |
| Knox, M | 1 |
| Robicsek, F | 1 |
| Masters, TN | 1 |
| Thomley, AM | 1 |
| Rice, HE | 1 |
| Morales-Reyna, J | 1 |
| Kløw, NE | 1 |
| Mortensen, E | 1 |
| Refsum, H | 1 |
| Piscione, F | 1 |
| Focaccio, A | 1 |
| Santinelli, V | 1 |
| De Paola, M | 1 |
| Villari, B | 1 |
| Spinazzi, A | 1 |
| Condorelli, M | 1 |
| Chiariello, M | 1 |
| Vik-Mo, H | 1 |
| Følling, M | 1 |
| Barth, P | 2 |
| Nordrehaug, JE | 1 |
| Bjørkhaug, A | 1 |
| Rosland, GA | 1 |
| Neiss, AC | 1 |
| Chastin, I | 1 |
| Erdmann, E | 1 |
| Torrents, A | 1 |
| Mauri, J | 1 |
| Piao, ZE | 2 |
| Murdock, DK | 2 |
| Hwang, MH | 2 |
| Raymond, RM | 1 |
| Scanlon, PJ | 2 |
| Giardina, JJ | 1 |
| Pacold, I | 1 |
| Loeb, HS | 1 |
| Reyes, CV | 1 |
| Feldman, RL | 1 |
| Jalowiec, DA | 1 |
| Hill, JA | 1 |
| Lambert, CR | 1 |
| Baudouy, PY | 1 |
| Lasry, JL | 2 |
| Lagneau, P | 2 |
| Abassade, P | 1 |
| Valleteau de Moulliac, M | 1 |
| Baudouy, P | 1 |
| Foster, CJ | 1 |
| Griffin, JF | 1 |
| Foult, JM | 2 |
| Nitenberg, A | 2 |
| Blanchet, F | 2 |
| Zouiouèche, S | 2 |
| Huyghebaert, MF | 1 |
| Fast, JH | 1 |
| Uyen, GJ | 1 |
| Heystraten, FM | 1 |
| de Boo, TM | 1 |
| Lemmens, WA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Benefit of Transradial Approach in Chronic Kidney Disease Population Undergoing Cardiac Catheterization, A Single Center Randomized Controlled Trial[NCT02933892] | Phase 4 | 100 participants (Anticipated) | Interventional | 2016-10-31 | Recruiting | ||
| Optical Imaging Measurement of Intravascular Solution Efficacy Trial[NCT01743872] | 23 participants (Actual) | Interventional | 2012-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The metric of image quality was the clear imaging field (CIF), which was defined as a cross section in which ≥270° of the vessel wall architecture was visualized. This has been used previously to quantify adequacy of clearance in OCT image comparison. Two independent observers, blinded to the flush medium used, analyzed all OCT frames in each pullback sequence. Any disagreement >10% was resolved with a consensus re-evaluation at a later time point by the same reviewers. Each individual cross section was assigned a designation of quality or insufficient quality; thus, a quality image proportion was generated for each run by taking the mean of each observer's determinations (NCT01743872)
Timeframe: 1 month
| Intervention | Clear imaging field (CIF) proportion (Mean) |
|---|---|
| Contrast Injection | .702 |
| Dextran Injection | .872 |
| CO2 Injection | .10 |
| Heparinized Saline | .743 |
(NCT01743872)
Timeframe: 1 month
| Intervention | percentage of plaque composition (Number) | |||
|---|---|---|---|---|
| Fibrotic, % | Calcific, % | Lipid, % | Normal, % | |
| Contrast Injection | 57.9 | 6.9 | 9.1 | 24.4 |
| Dextran Injection | 62.1 | 5.5 | 6.3 | 25.6 |
| Heparinized Saline | 63.0 | 5.4 | 6.5 | 22.9 |
| Overall | 61.0 | 6.0 | 7.3 | 24.3 |
2 reviews available for ioxaglate and Coronary Heart Disease
| Article | Year |
|---|---|
Comparative tolerability of contrast media used for coronary interventions.
Topics: Cardiovascular Diseases; Cardiovascular Surgical Procedures; Cardiovascular System; Clinical Trials | 2002 |
The protective effect of coronary collateral circulation on myocardial viability: a case of acute coronary occlusion.
Topics: Acute Disease; Angina, Unstable; Collateral Circulation; Coronary Angiography; Coronary Circulation; | 1994 |
18 trials available for ioxaglate and Coronary Heart Disease
| Article | Year |
|---|---|
Nonionic low-osmolar contrast media have no impact on major adverse cardiac events in patients undergoing coronary stenting with appropriate antiplatelet therapy.
Topics: Analysis of Variance; Angioplasty, Balloon, Coronary; Chi-Square Distribution; Contrast Media; Coron | 2003 |
Comparison of Hexabrix 320 and Conray 420 for left ventriculography in patients with coronary artery disease.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Contrast Media; Coronary Disease; Female; Hea | 1984 |
The haemodynamic effects of left ventriculography in coronary artery disease and mitral valve disease: a comparison of high and low osmolality contrast media.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Contrast Media; Coronary Angiography; Coronar | 1984 |
[Early hemodynamic reactions of an ionic low osmolar and a nonionic contrast medium].
Topics: Adult; Aged; Angiography; Cardiomyopathies; Contrast Media; Coronary Angiography; Coronary Disease; | 1984 |
Iodixanol in cardioangiography. A double-blind parallel comparison between iodixanol 320 mg I/ml and ioxaglate 320 mg I/ml.
Topics: Adult; Aged; Angiocardiography; Contrast Media; Coronary Disease; Double-Blind Method; Female; Human | 1994 |
Effects of an ionic versus a nonionic low osmolar contrast agent on the thrombotic complications of coronary angioplasty.
Topics: Angioplasty, Balloon, Coronary; Cardiac Catheterization; Coronary Angiography; Coronary Disease; Cor | 1993 |
Immediate and late adverse reactions in coronary angiography. A comparison between iodixanol and ioxaglate.
Topics: Contrast Media; Coronary Angiography; Coronary Disease; Double-Blind Method; Female; Hemodynamics; H | 1996 |
[A differentiated contrast medium in interventional cardiology. Strategy for the reduction of thromboembolic complications].
Topics: Angioplasty; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Coronary Disease; | 1998 |
Randomized trial of contrast media utilization in high-risk PTCA: the COURT trial.
Topics: Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Disease; Double-Blind Method; Female; | 2000 |
Are ioxaglate and iopamidol equally safe and well tolerated in cardiac angiography? A randomized, double-blind clinical study.
Topics: Adult; Aged; Angiography; Coronary Angiography; Coronary Disease; Double-Blind Method; Drug Toleranc | 1990 |
Influence of low osmolality contrast media on electrophysiology and hemodynamics in coronary angiography: differences between an ionic (ioxaglate) and a nonionic (iohexol) agent.
Topics: Adult; Aged; Blood Pressure; Coronary Angiography; Coronary Disease; Double-Blind Method; Electrocar | 1990 |
Comparison of sodium-meglumine ioxaglate and iopromide in coronary angiography.
Topics: Angiography; Clinical Trials as Topic; Contrast Media; Coronary Angiography; Coronary Disease; Doubl | 1989 |
[Iopromide 370 in coronaroventriculography, versus ioxaglate 320 mg/ml].
Topics: Angiocardiography; Contrast Media; Coronary Disease; Double-Blind Method; Female; Humans; Iohexol; I | 1989 |
[Comparative studies of diatrizoate, ioxaglate and iohexol as angiocardiographic contrast media].
Topics: Angiocardiography; Bradycardia; Coronary Disease; Diatrizoate; Female; Humans; Hypotension; Iohexol; | 1989 |
Contrast media-related complications during cardiac catheterization using Hexabrix or Renografin in high-risk patients.
Topics: Angiocardiography; Cardiac Catheterization; Clinical Trials as Topic; Contrast Media; Coronary Disea | 1988 |
[Evaluation of the myocardial ischemic and arrhythmogenic risk of digitalized angiography by venous route. Apropos of a comparative trial of ioxaglate and iopamidol].
Topics: Adult; Aged; Aged, 80 and over; Angiography; Arrhythmias, Cardiac; Coronary Disease; Female; Humans; | 1988 |
[Evaluation of cardiac tolerance of intravenous digital angiography].
Topics: Adolescent; Adult; Aged; Angiography; Arrhythmias, Cardiac; Coronary Disease; Electrocardiography; F | 1987 |
A comparison of the incidence of cardiac arrhythmias produced by two intravenous contrast media in coronary artery disease.
Topics: Arrhythmias, Cardiac; Coronary Disease; Humans; Infusions, Intravenous; Iothalamate Meglumine; Ioxag | 1987 |
23 other studies available for ioxaglate and Coronary Heart Disease
| Article | Year |
|---|---|
The increased histamine release in ischaemic heart disease patients undergoing coronaroangiography is not mediated by specific IgE.
Topics: Complement C3c; Complement C4; Contrast Media; Coronary Angiography; Coronary Disease; Drug Hypersen | 2002 |
Contrast-induced nephropathy after percutaneous coronary interventions in relation to chronic kidney disease and hemodynamic variables.
Topics: Aged; Chronic Disease; Contrast Media; Coronary Disease; Female; Follow-Up Studies; Hemodynamics; Hu | 2005 |
Visipaque (iodixanol) and hexabrix (ioxaglate) in renal insufficiency.
Topics: Acute Kidney Injury; Contrast Media; Coronary Angiography; Coronary Disease; Humans; Incidence; Ioxa | 2007 |
Evaluation and comparison between visipaque (iodixanol) and hexabrix (ioxaglate) in coronary angiography.
Topics: Acute Kidney Injury; Contrast Media; Coronary Angiography; Coronary Disease; Humans; Ioxaglic Acid; | 2007 |
Clinical experience with ioxaglate (Hexabrix) in selective coronary arteriography.
Topics: Adult; Aged; Angiocardiography; Cardiomyopathy, Dilated; Contrast Media; Coronary Angiography; Coron | 1984 |
[Comparison of amidotrizoate and ioxaglate in angiocardiography of chronic ischemic heart disease].
Topics: Angiocardiography; Contrast Media; Coronary Disease; Diatrizoate; Female; Humans; Iodobenzoates; Iox | 1983 |
[Comparative effects on left ventricular function in coronary patients of various contrast media used in coronarography: iopamidol, diatrizoate, ioxaglate].
Topics: Adult; Contrast Media; Coronary Angiography; Coronary Disease; Diatrizoate; Female; Heart Ventricles | 1983 |
Effects of contrast media used in angiocardiography on the mechanical performance and the relaxation of normal and ischaemic myocardium.
Topics: Angiocardiography; Animals; Cats; Contrast Media; Coronary Disease; In Vitro Techniques; Iopamidol; | 1984 |
Two new contrast media in coronary angiography.
Topics: Adult; Aged; Angiography; Blood Pressure; Contrast Media; Coronary Disease; Double-Blind Method; Dru | 1983 |
[Coronary angiography in chronic and acute coronary artery disease. Advantages of a low osmolality contrast medium].
Topics: Aged; Angiography; Blood Pressure; Contrast Media; Coronary Angiography; Coronary Disease; Diatrizoa | 1982 |
Platelet adhesion/aggregation in an in vitro model of coronary artery stenosis.
Topics: Aspirin; Contrast Media; Coronary Disease; Coronary Thrombosis; Diatrizoate; Diatrizoate Meglumine; | 1993 |
Platelets are degranulated by some, but not all, contrast media.
Topics: Aspirin; Cells, Cultured; Contrast Media; Coronary Angiography; Coronary Disease; Diatrizoate; Flow | 1996 |
Contrast nephropathy after coronary angioplasty in chronic renal insufficiency.
Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Disease; Cr | 1996 |
Evaluation of contrast agents for delineation of vessel wall boundary by intracoronary ultrasound after coronary angioplasty in human.
Topics: Aged; Albumins; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Disease; Coronary Vessels; | 1999 |
Index matching to improve optical coherence tomography imaging through blood.
Topics: Blood; Blood Flow Velocity; Blood Physiological Phenomena; Contrast Media; Coronary Disease; Dextran | 2001 |
Patient tolerance of ioxaglate and iopamidol in internal mammary artery arteriography.
Topics: Adult; Aged; Angiography; Coronary Artery Bypass; Coronary Disease; Diatrizoate; Female; Humans; Iop | 1992 |
Bench coronary cineangiography. A possible way to increase the number of hearts available for transplantation.
Topics: Animals; Autopsy; Cineangiography; Coronary Disease; Dogs; Evaluation Studies as Topic; Heart Transp | 1992 |
Left ventricular systolic and diastolic function during coronary arteriography before and after acute left ventricular failure in dogs. A comparison between iodixanol, iohexol and ioxaglate.
Topics: Acute Disease; Animals; Blood Pressure; Cardiac Output; Cardiac Output, Low; Contrast Media; Coronar | 1991 |
Hemodynamic abnormalities during coronary angiography: comparison of Hypaque-76, Hexabrix, and Omnipaque-350.
Topics: Angiography; Animals; Contrast Media; Coronary Angiography; Coronary Disease; Diatrizoate; Diatrizoa | 1989 |
The potential risk of thrombosis during coronary angiography using nonionic contrast media.
Topics: Angiography; Animals; Blood Coagulation; Contrast Media; Coronary Angiography; Coronary Disease; Cor | 1989 |
Effect of diltiazem on coronary reactive hyperemia in patients with flow-limiting coronary artery stenosis.
Topics: Adult; Cardiac Catheterization; Contrast Media; Coronary Angiography; Coronary Circulation; Coronary | 1986 |
Alterations in contrast medium-induced coronary reactive hyperemia after bepridil in patients with coronary artery disease.
Topics: Adult; Bepridil; Coronary Circulation; Coronary Disease; Female; Humans; Hyperemia; Ioxaglic Acid; M | 1985 |
Short-term hemodynamic effects of diatrizoate and ioxaglate contrast media in left ventriculography.
Topics: Adult; Aged; Blood Pressure; Cineangiography; Contrast Media; Coronary Disease; Diatrizoate; Diatriz | 1985 |