Page last updated: 2024-10-29

ioxaglate and Blood Clot

ioxaglate has been researched along with Blood Clot in 26 studies

Ioxaglic Acid: A low-osmolar, ionic contrast medium used in various radiographic procedures.
ioxaglic acid : A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an acetyl(methyl)amino group at the 5-position.

Research Excerpts

ExcerptRelevanceReference
" The nonionic CM iohexol triggers platelet beta-thromboglobulin (beta-TG) secretion, and thus may activate the platelets and promote thrombosis."7.70Iohexol, platelet activation and thrombosis. II. Iohexol-induced platelet secretion does not affect collagen-induced or tissue-factor-induced thrombus formation in blood that is anticoagulated with heparin and aspirin. ( Buchmann, M; Hamers, MJ; Sakariassen, KS; Stormorken, H, 1998)
"Ioxaglate and iodixanol were virtually inert."5.30Iohexol, platelet activation and thrombosis. I. Iohexol-induced platelet secretion does not affect thrombus formation in native blood. ( Barstad, RM; Hamers, MJ; Sakariassen, KS; Stormorken, H, 1998)
"Low-osmolar ionic (ioxaglate) or nonionic (iohexol) contrast material was administered to 14 patients undergoing pulmonary angiography for suspected pulmonary embolism."5.07Increased plasma levels of PAI-1 after administration of nonionic contrast medium in patients undergoing pulmonary angiography. ( Büller, HR; Hack, CE; Levi, M; Reekers, JA; ten Cate, JW; Van Beek, EJ, 1994)
" The nonionic CM iohexol triggers platelet beta-thromboglobulin (beta-TG) secretion, and thus may activate the platelets and promote thrombosis."3.70Iohexol, platelet activation and thrombosis. II. Iohexol-induced platelet secretion does not affect collagen-induced or tissue-factor-induced thrombus formation in blood that is anticoagulated with heparin and aspirin. ( Buchmann, M; Hamers, MJ; Sakariassen, KS; Stormorken, H, 1998)
"Thrombosis was measured over a blood exposure period of 2 hours by gamma camera imaging of 111In-platelets and by gamma counting of deposited 125I-fibrin."1.31Antithrombotic effects of ionic and non-ionic contrast media in nonhuman primates. ( Chronos, NA; Hanson, SR; Markou, CP, 2001)
"Ioxaglate and iodixanol were virtually inert."1.30Iohexol, platelet activation and thrombosis. I. Iohexol-induced platelet secretion does not affect thrombus formation in native blood. ( Barstad, RM; Hamers, MJ; Sakariassen, KS; Stormorken, H, 1998)
"Ioxaglate significantly inhibited thrombus growth (60% inhibition, P less than 0."1.28Effect on thrombus growth and thrombolysis of two types of osmolar contrast media in rabbits. ( Agnelli, G; Hoek, J; Levi, M; Pascucci, C; Sturk, A; Wouter ten Cate, J, 1990)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.69)18.7374
1990's14 (53.85)18.2507
2000's8 (30.77)29.6817
2010's2 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shah, B1
Berger, JS1
Allen, N1
Guo, Y1
Sedlis, SP1
Xu, J1
Perez, A1
Attubato, M1
Slater, J1
Feit, F1
Seto, AH1
Kern, MJ1
Esplugas, E2
Cequier, A2
Gomez-Hospital, JA1
Del Blanco, BG1
Jara, F2
Al Dieri, R1
Béguin, S1
Hemker, HC1
Jones, CI1
Goodall, AH1
Le Feuvre, C1
Batisse, A1
Collet, JP1
Batisse, JP1
Choussat, R1
Beygui, F1
Helft, G1
Montalescot, G1
Metzger, JP1
Abeyama, K1
Oh, S1
Kawano, K1
Nakajima, T1
Soejima, Y1
Nakano, K1
Maruyama, I1
Corot, C2
Stucker, O1
Duverger, JP1
Pons, C1
Vicaut, E1
Van Beek, EJ1
Levi, M2
Reekers, JA1
Hack, CE1
Büller, HR1
ten Cate, JW1
Mauri, J1
Soler, T1
Sala, J1
Sabate, X1
Sato, E1
Saito, I1
Barstad, RM2
Buchmann, MS1
Hamers, MJ3
Orning, L1
Orvim, U1
Stormorken, H3
Sakariassen, KS3
Buchmann, M1
Fay, WP2
Parker, AC1
Chronos, N1
Blanco, J1
Aguejouf, O1
Malfatti, E1
Doutremepuich, F1
Doutremepuich, C1
Markou, CP1
Chronos, NA1
Hanson, SR1
Schräder, R1
Zhu, Y1
Tomasiak, R1
Cornillac, A1
Belleville, J1
Eloy, R1
Mamon, JF1
Fareed, J1
Hoppensteadt, D1
Moncada, R1
Hwang, MH1
Piao, ZE1
Murdock, DK1
Messmore, HL1
Giardina, JJ1
Scanlon, PJ1
Pascucci, C1
Agnelli, G1
Sturk, A1
Hoek, J1
Wouter ten Cate, J1
Hoogewoud, HM1
Petropoulos, P1
Benichou, M1
Camilleri, JF1
Bernard, PJ1
Sarrat, P1
Habib, G1
Delaforte, C1
Serradimigni, A1

Reviews

1 review available for ioxaglate and Blood Clot

ArticleYear
Comparative tolerability of contrast media used for coronary interventions.
    Drug safety, 2002, Volume: 25, Issue:15

    Topics: Cardiovascular Diseases; Cardiovascular Surgical Procedures; Cardiovascular System; Clinical Trials

2002

Trials

5 trials available for ioxaglate and Blood Clot

ArticleYear
The assessment of thrombotic markers utilizing ionic versus non-ionic contrast during coronary angiography and intervention trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016, Volume: 88, Issue:5

    Topics: Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease; Female; Fibrinolysi

2016
Cardiac events after low osmolar ionic or isosmolar nonionic contrast media utilization in the current era of coronary angioplasty.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2006, Volume: 67, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Contrast Media; Coronary Angio

2006
Increased plasma levels of PAI-1 after administration of nonionic contrast medium in patients undergoing pulmonary angiography.
    Radiology, 1994, Volume: 193, Issue:3

    Topics: Antithrombin III; Contrast Media; Female; Humans; Iohexol; Ioxaglic Acid; Male; Middle Aged; Osmolar

1994
Contrast media influence on thrombotic risk during coronary angioplasty.
    Seminars in thrombosis and hemostasis, 1993, Volume: 19 Suppl 1

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Double-Blind Method; Drug Costs; Female

1993
Risk of clot formation with ionic and nonionic contrast media in cerebral angiography. Tama Contrast Media Study Group.
    Academic radiology, 1996, Volume: 3, Issue:11

    Topics: Blood Coagulation; Cerebral Angiography; Contrast Media; Female; Humans; Iohexol; Iopamidol; Ioxagli

1996

Other Studies

20 other studies available for ioxaglate and Blood Clot

ArticleYear
Does the AToMIC trial explode concerns of contrast coagulopathy?
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016, Volume: 88, Issue:5

    Topics: Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease; Fibrinolysis; Humans; Iox

2016
The ionic contrast medium ioxaglate interferes with thrombin-mediated feedback activation of factor V, factor VIII and platelets.
    Journal of thrombosis and haemostasis : JTH, 2003, Volume: 1, Issue:2

    Topics: Abciximab; Angiography; Antibodies, Monoclonal; Contrast Media; Drug Interactions; Factor V; Factor

2003
Differential effects of the iodinated contrast agents Ioxaglate, Iohexol and Iodixanol on thrombus formation and fibrinolysis.
    Thrombosis research, 2003, Volume: 112, Issue:1-2

    Topics: Blood Platelets; Contrast Media; Dose-Response Relationship, Drug; Fibrinolysis; Humans; Iohexol; Io

2003
Nonionic contrast agents produce thrombotic effect by inducing adhesion of leukocytes on human endothelium.
    Biochemical and biophysical research communications, 1995, Jul-26, Volume: 212, Issue:3

    Topics: Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Contrast Media; Diatrizoate; E-Selectin; En

1995
Effects of iodinated contrast agents on the formation of platelet thrombi in rat arterioles.
    Investigative radiology, 1994, Volume: 29 Suppl 2

    Topics: Animals; Arterioles; Contrast Media; Iohexol; Ioxaglic Acid; Mesenteric Arteries; Microscopy, Video;

1994
Effects of ionic and nonionic contrast media on endothelium and on arterial thrombus formation.
    Acta radiologica (Stockholm, Sweden : 1987), 1996, Volume: 37, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Cells, Cultured; Contrast Media; Endothelium, Vascular; Female; Huma

1996
Iohexol, platelet activation and thrombosis. I. Iohexol-induced platelet secretion does not affect thrombus formation in native blood.
    Acta radiologica (Stockholm, Sweden : 1987), 1998, Volume: 39, Issue:4

    Topics: beta-Thromboglobulin; Blood Donors; Blood Platelets; Collagen; Contrast Media; Dose-Response Relatio

1998
Iohexol, platelet activation and thrombosis. II. Iohexol-induced platelet secretion does not affect collagen-induced or tissue-factor-induced thrombus formation in blood that is anticoagulated with heparin and aspirin.
    Acta radiologica (Stockholm, Sweden : 1987), 1998, Volume: 39, Issue:4

    Topics: Anticoagulants; Aspirin; beta-Thromboglobulin; Blood Platelets; Collagen; Contrast Media; Drug Inter

1998
Effects of radiographic contrast agents on thrombin formation and activity.
    Thrombosis and haemostasis, 1998, Volume: 80, Issue:2

    Topics: Cardiac Catheterization; Contrast Media; Diatrizoate; Enzyme Inhibitors; Fibrin; Humans; Ioxaglic Ac

1998
Thrombogenic potential of non-ionic contrast media--fact or fiction? By Rainer Schrader.
    European journal of radiology, 1998, Volume: 28, Issue:1

    Topics: Contrast Media; Humans; Iohexol; Ioxaglic Acid; Risk Factors; Thrombosis

1998
Thrombogenic potential of contrast media in an experimental model of laser-induced thrombosis.
    Thrombosis research, 2000, Nov-01, Volume: 100, Issue:3

    Topics: Animals; Contrast Media; Diatrizoate; Disease Models, Animal; Dose-Response Relationship, Drug; Iohe

2000
Antithrombotic effects of ionic and non-ionic contrast media in nonhuman primates.
    Thrombosis and haemostasis, 2001, Volume: 85, Issue:3

    Topics: Animals; Arteriovenous Shunt, Surgical; Blood Flow Velocity; Contrast Media; Disease Models, Animal;

2001
Ionic or non-ionic contrast media in stent placement.
    European heart journal, 2001, Volume: 22, Issue:21

    Topics: Cohort Studies; Contrast Media; Coronary Angiography; Heart Diseases; Humans; Ioxaglic Acid; Stents;

2001
Do clinically relevant circulating concentrations of radiographic contrast agents inhibit platelet-dependent arterial thrombosis?
    Thrombosis research, 2002, Mar-01, Volume: 105, Issue:5

    Topics: Animals; Arterial Occlusive Diseases; Blood Circulation; Blood Coagulation; Blood Flow Velocity; Car

2002
Scanning electron microscopic analysis of catheters during routine angiographic procedures. Role of the contrast agent. The European Clotting Group.
    Investigative radiology, 1991, Volume: 26 Suppl 1

    Topics: Angiocardiography; Angiography; Blood; Catheterization, Peripheral; Drug Interactions; Humans; Iohex

1991
Lack of inhibition of thrombin generation by nonionic contrast media.
    Thrombosis research, 1991, Jan-15, Volume: 61, Issue:2

    Topics: Antithrombin III; Contrast Media; Diatrizoate; Humans; In Vitro Techniques; Iohexol; Ioxaglic Acid;

1991
Risk of thromboembolism during diagnostic and interventional cardiac procedures with nonionic contrast media.
    Radiology, 1990, Volume: 174, Issue:2

    Topics: Animals; Cardiac Catheterization; Contrast Media; Coronary Angiography; Diatrizoate; Dogs; Female; H

1990
Effect on thrombus growth and thrombolysis of two types of osmolar contrast media in rabbits.
    Investigative radiology, 1990, Volume: 25, Issue:5

    Topics: Animals; Contrast Media; Iohexol; Ioxaglic Acid; Osmolar Concentration; Rabbits; Stimulation, Chemic

1990
Renal embolization: a study of the interaction of contrast media and ethanol.
    Cardiovascular and interventional radiology, 1987, Volume: 10, Issue:4

    Topics: Aged; Drug Interactions; Embolization, Therapeutic; Ethanol; Humans; Iohexol; Iopamidol; Ioxaglic Ac

1987
Comparison of two-dimensional echocardiography with scanography and indium-111 platelet scintigraphy in detection of intracardiac thrombi.
    Acta cardiologica, 1988, Volume: 43, Issue:2

    Topics: Blood Platelets; Contrast Media; Echocardiography; Female; Heart; Heart Diseases; Humans; Indium Rad

1988