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ioxaglate and Acute Kidney Injury

ioxaglate has been researched along with Acute Kidney Injury in 19 studies

Ioxaglic Acid: A low-osmolar, ionic contrast medium used in various radiographic procedures.
ioxaglic acid : A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an acetyl(methyl)amino group at the 5-position.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
" The influence of intraarterial injection of CO2 with small added amounts of ioxaglate (200 mgI/mL) or ioxaglate alone on renal function in patients with suspected renal artery stenosis was studied in a prospective, randomized study."5.11Renal effects of CO2 and iodinated contrast media in patients undergoing renovascular intervention: a prospective, randomized study. ( Bergqvist, D; Boström-Ardin, A; Eklöf, H; Eriksson, LG; Hägg, A; Hansell, P; Hellberg, O; Liss, P; Löfberg, AM; Nilsson, H; Nyman, R; Olsson, U; Orndahl, P, 2005)
"Rats received nitric oxide synthase inhibitor L-NAME (10 mg/kg) and cyclooxygenase inhibitor indomethacin (10 mg/kg) to induce the risk for developing iodinated contrast-induced acute kidney injury before receiving one of the interventions: NAC, furosemide, or placebo."3.80Efficacy of preventive interventions for iodinated contrast-induced acute kidney injury evaluated by intrarenal oxygenation as an early marker. ( Franklin, T; Li, LP; Lu, J; Papadopoulou, MV; Prasad, PV; Solomon, R; Thacker, J; Zhou, Y, 2014)
"The only predictive factor for acute renal failure was the quantity of contrast medium (316+/-141 vs 173+/-115 ml, p<0."2.71[Absence of nephro-protective effect of acetylcysteine in patients with chronic renal failure investigated by coronary angiography]. ( Batisse, JP; Beygui, F; El Mahmoud, R; Helft, G; Le Feuvre, C; Le Quan Sang, KH; Metzger, JP, 2003)
"Four patients reacting with acute renal failure despite using low osmolar contrast media are reported."1.28Acute renal failure caused by low-osmolar radiographic contrast media in patients with diabetic nephropathy. ( Larsson, R; Lundberg, M; Nikonoff, T; Nyberg, P; Skau, T; Spångberg-Viklund, B, 1989)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's9 (47.37)18.2507
2000's5 (26.32)29.6817
2010's3 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, LP2
Lu, J2
Zhou, Y2
Papadopoulou, MV2
Franklin, T2
Bokhary, U1
Solomon, R2
Sen, A1
Prasad, PV2
Thacker, J1
Giustino, G1
Baber, U1
Mastoris, I1
Vlachojannis, GJ1
Yu, J1
Teirstein, PS1
Downey, WE1
Batchelor, WB1
Casterella, PJ1
Nikolsky, E1
Wong, SC1
Theodoropoulos, KN1
Dangas, GD1
Mehran, R1
Agrawal, V1
Swami, A1
Kosuri, R1
Alsabbagh, M1
Agarwal, M1
Samarapungavan, D1
Rocher, LL1
McCullough, PA1
El Mahmoud, R1
Le Feuvre, C1
Le Quan Sang, KH1
Helft, G1
Beygui, F1
Batisse, JP1
Metzger, JP1
Liss, P3
Eklöf, H1
Hellberg, O1
Hägg, A1
Boström-Ardin, A1
Löfberg, AM1
Olsson, U1
Orndahl, P1
Nilsson, H1
Hansell, P2
Eriksson, LG1
Bergqvist, D1
Nyman, R1
Deray, G3
Persson, P1
Idée, JM2
Santus, R2
Beaufils, H2
Balut, C2
Huntsman, AM1
Bourbouze, R2
Koeltz, B1
Jouanneau, C2
Bonnemain, B2
Touati, C1
Doucet, D1
Nagappan, R1
Williams, LC1
List, AR1
Nikonoff, T2
Skau, T2
Berglund, J1
Nyberg, P2
Spångberg-Viklund, B2
Larsson, R2
Laranja, SM1
Ajzen, H1
Schor, N1
Nygren, A2
Erikson, U1
Ulfendahl, HR1
Brillet, G1
Baumelou, A1
Jacobs, C1
Campbell, DR1
Flemming, BK1
Mason, WF1
Jackson, SA1
Hirsch, DJ1
MacDonald, KJ1
Lundberg, M1
Aron, NB1
Feinfeld, DA1
Peters, AT1
Lynn, RI1

Reviews

1 review available for ioxaglate and Acute Kidney Injury

ArticleYear
Acute renal failure due to low osmolar radiographic contrast medium.
    The New Zealand medical journal, 1993, Sep-08, Volume: 106, Issue:963

    Topics: Acute Kidney Injury; Aged; Female; Femoral Artery; Humans; Intermittent Claudication; Ioxaglic Acid;

1993

Trials

5 trials available for ioxaglate and Acute Kidney Injury

ArticleYear
One-year results of the ICON (Ionic versus non-ionic Contrast to Obviate worsening Nephropathy after angioplasty in chronic renal failure patients) Study.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016, Volume: 87, Issue:4

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Contrast Media; Corona

2016
[Absence of nephro-protective effect of acetylcysteine in patients with chronic renal failure investigated by coronary angiography].
    Archives des maladies du coeur et des vaisseaux, 2003, Volume: 96, Issue:12

    Topics: Acetylcysteine; Acute Kidney Injury; Aged; Contrast Media; Coronary Angiography; Female; Humans; Iox

2003
Renal effects of CO2 and iodinated contrast media in patients undergoing renovascular intervention: a prospective, randomized study.
    Journal of vascular and interventional radiology : JVIR, 2005, Volume: 16, Issue:1

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Angiography, Digital Subtraction; Carbon Dioxid

2005
Nephrotoxicity of low-osmolality contrast media.
    Renal failure, 1997, Volume: 19, Issue:2

    Topics: Acute Kidney Injury; Analysis of Variance; Contrast Media; Humans; Incidence; Ioxaglic Acid; Kidney

1997
A comparative study of the nephrotoxicity of iohexol, iopamidol and ioxaglate in peripheral angiography.
    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 1990, Volume: 41, Issue:3

    Topics: Acute Kidney Injury; Aged; Angiography; Creatinine; Diabetes Mellitus; Double-Blind Method; Female;

1990

Other Studies

13 other studies available for ioxaglate and Acute Kidney Injury

ArticleYear
Evaluation of intrarenal oxygenation in iodinated contrast-induced acute kidney injury-susceptible rats by blood oxygen level-dependent magnetic resonance imaging.
    Investigative radiology, 2014, Volume: 49, Issue:6

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Contrast Media; Feasibility Studies;

2014
Efficacy of preventive interventions for iodinated contrast-induced acute kidney injury evaluated by intrarenal oxygenation as an early marker.
    Investigative radiology, 2014, Volume: 49, Issue:10

    Topics: Acetylcysteine; Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Contrast Media; Dise

2014
Contrast-induced acute kidney injury in renal transplant recipients after cardiac catheterization.
    Clinical nephrology, 2009, Volume: 71, Issue:6

    Topics: Acute Kidney Injury; Cardiac Catheterization; Contrast Media; Creatinine; Female; Humans; Incidence;

2009
Visipaque (iodixanol) and hexabrix (ioxaglate) in renal insufficiency.
    Journal of the American College of Cardiology, 2007, Apr-17, Volume: 49, Issue:15

    Topics: Acute Kidney Injury; Contrast Media; Coronary Angiography; Coronary Disease; Humans; Incidence; Ioxa

2007
Evaluation and comparison between visipaque (iodixanol) and hexabrix (ioxaglate) in coronary angiography.
    Journal of the American College of Cardiology, 2007, Apr-17, Volume: 49, Issue:15

    Topics: Acute Kidney Injury; Contrast Media; Coronary Angiography; Coronary Disease; Humans; Ioxaglic Acid;

2007
Comparative effects of low- and high-osmolar contrast media on the renal function during early degenerative gentamicin-induced nephropathy in rats.
    American journal of nephrology, 1995, Volume: 15, Issue:1

    Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Creatinine; Diatrizoate; Gentamicins; Glomerula

1995
Modulation of the renal effects of contrast media by endothelium-derived nitric oxide in the rat.
    Investigative radiology, 1993, Volume: 28, Issue:9

    Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Arginine; Creatinine; Iohexol; Ioxaglic Acid; K

1993
Effects of femoral arteriography and low osmolar contrast agents on renal function.
    Acta radiologica (Stockholm, Sweden : 1987), 1993, Volume: 34, Issue:1

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Angiography; Contrast Media; Diabetes Mellitus;

1993
Injection of low and iso-osmolar contrast medium decreases oxygen tension in the renal medulla.
    Kidney international, 1998, Volume: 53, Issue:3

    Topics: Acute Kidney Injury; Animals; Contrast Media; Hypoxia; Injections, Intravenous; Iohexol; Ioxaglic Ac

1998
Contrast media and regional renal blood flow. A study of the effects of ionic and non-ionic monomeric and dimeric contrast media in the rat.
    Acta radiologica. Supplementum, 1992, Volume: 378 ( Pt 3)

    Topics: Acute Kidney Injury; Animals; Contrast Media; Dehydration; Erythrocyte Aggregation; Glomerular Filtr

1992
Acute renal failure following coronary arteriography and ventriculography with ioxaglate, a low-osmolality radiocontrast agent.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1990, Volume: 16, Issue:5

    Topics: Acute Kidney Injury; Humans; Ioxaglic Acid; Osmolar Concentration

1990
Acute renal failure caused by low-osmolar radiographic contrast media in patients with diabetic nephropathy.
    Scandinavian journal of urology and nephrology, 1989, Volume: 23, Issue:4

    Topics: Acute Kidney Injury; Adult; Aged; Angiography; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Fe

1989
Acute renal failure associated with ioxaglate, a low-osmolality radiocontrast agent.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1989, Volume: 13, Issue:3

    Topics: Acute Kidney Injury; Aged; Coronary Angiography; Female; Heart Ventricles; Humans; Ioxaglic Acid; Ma

1989