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iothalamic acid and Acute Kidney Failure

iothalamic acid has been researched along with Acute Kidney Failure in 34 studies

Iothalamic Acid: A contrast medium in diagnostic radiology with properties similar to those of diatrizoic acid. It is used primarily as its sodium and meglumine (IOTHALAMATE MEGLUMINE) salts.

Research Excerpts

ExcerptRelevanceReference
"N-acetylcysteine (NAC) or sodium bicarbonate (NaHCO3), singly or combined, inconsistently prevent patients exposed to radiographic contrast media from developing contrast-induced acute kidney injury (CI-AKI)."9.19Do intravenous N-acetylcysteine and sodium bicarbonate prevent high osmolal contrast-induced acute kidney injury? A randomized controlled trial. ( Caixeta, A; Inda-Filho, AJ; Manggini, M; Schor, N, 2014)
"N-acetylcysteine (NAC) or sodium bicarbonate (NaHCO3), singly or combined, inconsistently prevent patients exposed to radiographic contrast media from developing contrast-induced acute kidney injury (CI-AKI)."5.19Do intravenous N-acetylcysteine and sodium bicarbonate prevent high osmolal contrast-induced acute kidney injury? A randomized controlled trial. ( Caixeta, A; Inda-Filho, AJ; Manggini, M; Schor, N, 2014)
" Recognizing the high incidence of RCIN in humans with severe congestive heart failure (CHF), this study was designed to test the hypotheses that dogs with experimental CHF are at increased risk for RCIN and that pharmacologic renal levels of atrial natriuretic factor (ANF) can prevent RCIN in this model."3.68Induction and prevention of radiocontrast-induced nephropathy in dogs with heart failure. ( Burnett, JC; Cavero, PG; Margulies, KB; McKinley, LJ, 1990)
" These data indicate that DA and IA are toxic to renal cortical slices, and this is a more sensitive model than previously used cell culture systems."1.35Characterization of a novel model for investigation of radiocontrast nephrotoxicity. ( Ball, JG; Duffy, SP; Harmon, RC; Terneus, MV; Valentovic, MA, 2009)
"Treatment with furosemide was used to study HIF expression under conditions of ameliorated tissue injury."1.33Up-regulation of HIF in experimental acute renal failure: evidence for a protective transcriptional response to hypoxia. ( Bachmann, S; Eckardt, KU; Frei, U; Goldfarb, M; Griethe, W; Heyman, SN; Reinke, P; Rosen, S; Rosenberger, C; Shina, A, 2005)
"In a model of radiocontrast-induced acute renal failure, DNA breaks were detected selectively along thick ascending limbs as early as 15 minutes following insult, preceding overt morphological damage."1.29Rapid DNA fragmentation from hypoxia along the thick ascending limb of rat kidneys. ( Baehr, PH; Beeri, R; Ben-Sasson, SA; Brezis, M; Rosen, S; Symon, Z; Zager, RA, 1995)
"Treatment with furosemide and/or normal saline prevented both the decline in renal function and mTAL injury."1.28Protective role of furosemide and saline in radiocontrast-induced acute renal failure in the rat. ( Brezis, M; Greenfeld, Z; Heyman, SN; Rosen, S, 1989)
"Since human acute renal failure (ARF) is frequently the result of multiple rather than single insults, we used a combination of treatments to induce ARF in rats."1.27Acute renal failure with selective medullary injury in the rat. ( Brezis, M; Epstein, FH; Greenfeld, Z; Heyman, SN; Lechene, C; Reubinoff, CA; Rosen, S, 1988)
"Prior acute renal failure (ARF) induced by either glycerol (G) or mercury provides protection against rechallenge with the same agent or the other."1.27Protection against acute renal failure by prior acute renal failure: differences between myohemoglobinuric and ischemic models. ( Hollenberg, NK; Wilkes, BM, 1987)
"This might be an aberrant form of acute renal failure with multiple wedge-shaped contrast enhancement."1.27Persistent wedge-shaped contrast enhancement of the kidney. ( Futyu, Y; Ishikawa, I; Onouchi, Z; Saito, Y; Shinoda, A; Tateishi, K; Yuri, T, 1985)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199023 (67.65)18.7374
1990's7 (20.59)18.2507
2000's2 (5.88)29.6817
2010's2 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, LP1
Lu, J1
Zhou, Y1
Papadopoulou, MV1
Franklin, T1
Bokhary, U1
Solomon, R1
Sen, A1
Prasad, PV1
Inda-Filho, AJ1
Caixeta, A1
Manggini, M1
Schor, N1
Harmon, RC1
Duffy, SP1
Terneus, MV1
Ball, JG1
Valentovic, MA1
Rosenberger, C1
Heyman, SN3
Rosen, S5
Shina, A1
Goldfarb, M1
Griethe, W1
Frei, U1
Reinke, P1
Bachmann, S1
Eckardt, KU1
Chevrot, L1
Sarrat, P1
Martin-Bouveyron, C1
Koskas, A1
Beeri, R1
Symon, Z2
Brezis, M5
Ben-Sasson, SA1
Baehr, PH1
Zager, RA1
Agmon, Y2
Peleg, H1
Greenfeld, Z3
Fuchs, S1
Weiss, O1
Nephesh, I1
Moshe, R1
Flyvbjerg, A1
Raz, I1
Older, RA1
Miller, JP1
Jackson, DC1
Johnsrude, IS1
Thompson, WM1
Byrd, LH1
Sherman, RL1
Stenzel, KH1
Rubin, AL1
Hanaway, J1
Black, J1
Swartz, RD1
Rubin, JE1
Leeming, BW1
Silva, P1
Rao, MS1
Bapna, BC1
Vaidyanathan, S1
Chugh, KS1
Sodhi, JS1
Mamdani, BH1
Mehta, PK1
Mahurkar, SD1
Sassoon, H1
Dunea, G1
Nygren, A1
Qiu, C1
Valentin, JP1
Chen, XW1
Wiedemann, E1
Humphreys, MH1
Margulies, KB2
Hildebrand, FL1
Heublein, DM1
Burnett, JC2
McKinley, LJ1
Cavero, PG1
Reubinoff, CA1
Lechene, C1
Epstein, FH1
Davies, RP1
Sage, MR1
Wilkes, BM1
Hollenberg, NK1
Ishikawa, I1
Tateishi, K1
Onouchi, Z1
Saito, Y1
Futyu, Y1
Shinoda, A1
Yuri, T1
Brown, CB1
Glancy, JJ1
Fry, IK1
Cattell, WR1
Bahlmann, J1
Gollnisch, HJ1
Port, FK1
Wagoner, RD1
Fulton, RE1
Kleinknecht, D1
Deloux, J1
Homberg, JC1
Saxton, HM1
Hinshaw, LB1
Archer, LL1
Parry, WL1
Shires, TK1
Teal, JS1
Rumbaugh, CL1
Segall, HD1
Bergeron, RT1
Scanlan, RL1
LĂ©lek, I3
Pokorny, L1
Lasser, EC1
Lang, JH1
Zawadzki, ZA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravenous High Dose of N-acetylcysteine and Sodium Bicarbonate for the Prevention of Contrast-induced Acute Injury: a Randomized Controlled Trial[NCT01612013]500 participants (Actual)Interventional2005-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for iothalamic acid and Acute Kidney Failure

ArticleYear
Review article: urography.
    The British journal of radiology, 1969, Volume: 42, Issue:497

    Topics: Acetrizoic Acid; Acute Kidney Injury; Contrast Media; Diatrizoate; Diuresis; Glomerular Filtration R

1969

Trials

3 trials available for iothalamic acid and Acute Kidney Failure

ArticleYear
Do intravenous N-acetylcysteine and sodium bicarbonate prevent high osmolal contrast-induced acute kidney injury? A randomized controlled trial.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Acetylcysteine; Acute Kidney Injury; Administration, Intravenous; Contrast Media; Coronary Angiograp

2014
[Radioclinical evaluation of a new opacifying agent during intravenous urography in renal failure patients].
    Annales de radiologie, 1983, Volume: 26, Issue:8 Pt 2

    Topics: Acute Kidney Injury; Adult; Aged; Clinical Trials as Topic; Contrast Media; Female; Humans; Injectio

1983
Angiographically induced renal failure and its radiographic detection.
    AJR. American journal of roentgenology, 1976, Volume: 126, Issue:5

    Topics: Acute Kidney Injury; Angiography; Creatinine; Diatrizoate; Humans; Iothalamic Acid; Prospective Stud

1976

Other Studies

30 other studies available for iothalamic acid and Acute Kidney Failure

ArticleYear
Evaluation of intrarenal oxygenation in iodinated contrast-induced acute kidney injury-susceptible rats by blood oxygen level-dependent magnetic resonance imaging.
    Investigative radiology, 2014, Volume: 49, Issue:6

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Contrast Media; Feasibility Studies;

2014
Characterization of a novel model for investigation of radiocontrast nephrotoxicity.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:3

    Topics: Acute Kidney Injury; Animals; Contrast Media; Diatrizoate; Disease Models, Animal; Dose-Response Rel

2009
Up-regulation of HIF in experimental acute renal failure: evidence for a protective transcriptional response to hypoxia.
    Kidney international, 2005, Volume: 67, Issue:2

    Topics: Acute Kidney Injury; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Hypoxia; Furosemide

2005
Rapid DNA fragmentation from hypoxia along the thick ascending limb of rat kidneys.
    Kidney international, 1995, Volume: 47, Issue:6

    Topics: Acute Kidney Injury; Animals; Apoptosis; Biomarkers; DNA; DNA Damage; Hypoxia; In Vitro Techniques;

1995
Nitric oxide and prostanoids protect the renal outer medulla from radiocontrast toxicity in the rat.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:3

    Topics: Acute Kidney Injury; Animals; Arginine; Humans; Indomethacin; Iothalamic Acid; Kidney Cortex; Kidney

1994
The endogenous insulin-like growth factor system in radiocontrast nephropathy.
    The American journal of physiology, 1998, Volume: 274, Issue:3

    Topics: Acute Kidney Injury; Animals; Contrast Media; Gene Expression; Insulin-Like Growth Factor Binding Pr

1998
Computerized tomography-induced acute renal failure.
    Archives of internal medicine, 1979, Volume: 139, Issue:4

    Topics: Acute Kidney Injury; Adult; Aged; Female; Humans; Iothalamic Acid; Male; Middle Aged; Tomography, X-

1979
Renal failure following contrast injection for computerized tomography.
    JAMA, 1977, Nov-07, Volume: 238, Issue:19

    Topics: Acute Kidney Injury; Aged; Female; Humans; Injections, Intravenous; Iothalamic Acid; Risk; Tomograph

1977
Renal failure following major angiography.
    The American journal of medicine, 1978, Volume: 65, Issue:1

    Topics: Acute Kidney Injury; Adult; Aged; Angiography; Contrast Media; Diatrizoate; Female; Humans; Iothalam

1978
Infusion pyelography in anuric patients.
    The Journal of urology, 1976, Volume: 116, Issue:3

    Topics: Acute Kidney Injury; Adult; Aged; Anuria; Diagnosis, Differential; Female; Humans; Infusions, Parent

1976
High-dose bolus urography. A superior technique in advanced renal failure.
    JAMA, 1975, Dec-08, Volume: 234, Issue:10

    Topics: Acute Kidney Injury; Humans; Injections; Iothalamic Acid; Kidney; Kidney Failure, Chronic; Tomograph

1975
Contrast media and regional renal blood flow. A study of the effects of ionic and non-ionic monomeric and dimeric contrast media in the rat.
    Acta radiologica. Supplementum, 1992, Volume: 378 ( Pt 3)

    Topics: Acute Kidney Injury; Animals; Contrast Media; Dehydration; Erythrocyte Aggregation; Glomerular Filtr

1992
Acute unilateral nephrectomy elicits a specific increase in plasma of peptides derived from the N-terminal region of proopiomelanocortin.
    Journal of the American Society of Nephrology : JASN, 1992, Volume: 3, Issue:5

    Topics: Acute Kidney Injury; Adrenocorticotropic Hormone; Animals; Atrial Natriuretic Factor; Blood Pressure

1992
Radiocontrast increases plasma and urinary endothelin.
    Journal of the American Society of Nephrology : JASN, 1991, Volume: 2, Issue:5

    Topics: Acute Kidney Injury; Animals; Atrial Natriuretic Factor; Contrast Media; Dogs; Drug Combinations; En

1991
Induction and prevention of radiocontrast-induced nephropathy in dogs with heart failure.
    Kidney international, 1990, Volume: 38, Issue:6

    Topics: Acute Kidney Injury; Animals; Atrial Natriuretic Factor; Cardiac Pacing, Artificial; Contrast Media;

1990
Protective role of furosemide and saline in radiocontrast-induced acute renal failure in the rat.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1989, Volume: 14, Issue:5

    Topics: Acute Kidney Injury; Animals; Furosemide; Indomethacin; Iothalamic Acid; Kidney; Male; Rats; Rats, I

1989
Acute renal failure with selective medullary injury in the rat.
    The Journal of clinical investigation, 1988, Volume: 82, Issue:2

    Topics: Acute Kidney Injury; Animals; Creatinine; Hemodynamics; In Vitro Techniques; Indomethacin; Inulin; I

1988
Contract-induced renal failure: detection by the persistent nephrogram. A case report.
    Australasian radiology, 1987, Volume: 31, Issue:4

    Topics: Acute Kidney Injury; Adult; Contrast Media; Humans; Iothalamic Acid; Kidney; Male; Radiography; Time

1987
Protection against acute renal failure by prior acute renal failure: differences between myohemoglobinuric and ischemic models.
    Nephron, 1987, Volume: 47, Issue:3

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Glycerol; Iod

1987
Persistent wedge-shaped contrast enhancement of the kidney.
    Urologic radiology, 1985, Volume: 7, Issue:1

    Topics: Acute Kidney Injury; Adult; Humans; Iothalamic Acid; Kidney; Male; Time Factors; Tomography, X-Ray C

1985
High-dose excretion urography in oliguric renal failure.
    Lancet (London, England), 1970, Nov-07, Volume: 2, Issue:7680

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Anuria; Blood Urea Nitrogen; Child, Preschool; Contras

1970
[Kidney function after infusion pyelography].
    Klinische Wochenschrift, 1973, Mar-15, Volume: 51, Issue:6

    Topics: Acute Kidney Injury; Adolescent; Adult; Blood Pressure; Blood Urea Nitrogen; Creatinine; Diuresis; F

1973
Acute renal failure after angiography.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1974, Volume: 121, Issue:3

    Topics: Acute Kidney Injury; Adult; Aged; Angiography; Anuria; Aortography; Cardiac Catheterization; Creatin

1974
Acute renal failure after intravenous urography: detection of antibodies against contrast media.
    Clinical nephrology, 1974, Volume: 2, Issue:3

    Topics: Acute Kidney Injury; Aged; Arthritis, Rheumatoid; Chemical Phenomena; Chemical Precipitation; Chemis

1974
Renal hemodynamics and function in response to renal artery occlusion in canine and primate kidneys.
    Investigative urology, 1970, Volume: 7, Issue:5

    Topics: Acute Kidney Injury; Animals; Blood Flow Velocity; Blood Pressure; Dogs; Glomerular Filtration Rate;

1970
Acute renal failure following spinal angiography with methylglucamine iothalamate. Case report.
    Radiology, 1972, Volume: 104, Issue:3

    Topics: Acute Kidney Injury; Amino Sugars; Angiography; Aortography; Blood Urea Nitrogen; Creatinine; Humans

1972
[Acute kidney damage caused by aortography. Experiments with dogs].
    Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1971, Volume: 114, Issue:6

    Topics: Acute Kidney Injury; Albuminuria; Angiography; Animals; Aortography; Contrast Media; Diatrizoate; Do

1971
[Animal experiment studies on acute renal injury due to selective renal arteriography].
    Radiologia diagnostica, 1971, Volume: 12, Issue:6

    Topics: Acute Kidney Injury; Angiography; Animals; Child, Preschool; Contrast Media; Diatrizoate; Dogs; Hemo

1971
[Studies on the nephrotoxicity of iothalamate containing contrast media (conray, angio-conray) by means of experimental renal angiographies].
    Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1967, Volume: 106, Issue:2

    Topics: Acute Kidney Injury; Angiography; Animals; Contrast Media; Dogs; Iothalamic Acid; Kidney; Kidney Glo

1967
Contrast media. Myeloma protein precipitates in urography.
    JAMA, 1966, Nov-21, Volume: 198, Issue:8

    Topics: Acute Kidney Injury; Cholangiography; Contrast Media; Diatrizoate; Humans; In Vitro Techniques; Inje

1966