iothalamate-meglumine and Muscle-Cramp

In 570 patients an examination of the subarachnoideal space was performed. In 77 of them oily contrast media, in 93 oxygen and in the remaining 400 patients different water-soluble contrast media were used, including Conray 60, Dimer X and Amipaque. Neurotoxic spinal complications occurred in 12 of the 400 patients investigated with hydrosoluble agents (i.e. in 3%). In one of them after investigation with Dimer X, intense cramps in the lower extremities caused a fracture of the femoral neck within a few hours after the investigation. In another patient, investigated with Amipaque, a psychotic reaction with amentia and paranoid symptoms developed, which disappeared completely after 4 days.

Topics: Contrast Media; Humans; Iodized Oil; Iophendylate; Iothalamate Meglumine; Male; Metrizamide; Middle Aged; Muscle Cramp; Myelography; Paranoid Disorders; Spinal Nerve Roots; Stearates

Topics: Animals; Cats; Chemical Phenomena; Chemistry; Electromyography; Female; Hemodynamics; Iodobenzoates; Iothalamate Meglumine; Iothalamic Acid; Lumbosacral Plexus; Male; Metrizamide; Muscle Cramp; Myelography; Pressure; Spinal Nerve Roots; Urinary Bladder