iothalamate-meglumine and Hypersensitivity

After more than 2000 endoscopic retrograde cholangiopancreaticographies (ERCP) without contrast medium allergy, a case of severe allergic shock induced by contrast medium injected into the pancreatic duct is reported. The indication for ERCP in patients with known allergy to contrast media must therefore be restricted to those cases in which other examination procedures have given no useful results and yet diagnostic evaluation is vital to the interests of the patient.

Topics: Cholangiography; Endoscopy; Humans; Hypersensitivity; Iothalamate Meglumine; Middle Aged; Pancreatic Diseases

There were incidences of 0.7% severe and 5.5% mild complications in 1,971 direct puncture carotid angiograms done over a 5-year period. In 1,035 retrograde branchial angiograms, there was a 0.6% incidence of severe, and a 4.7% incidence of mild, complications. Complications tended to increase with increasing age of the patient. Brachial angiography is virtually free of life-threatening complications, and the incidence of neurological sequelae was markedly less than that shown by a comparable analysis of catheter angiography. Of patients undergoing 1,542 fractional pneumoencephalograms, 2 had severe complications.

Topics: Adolescent; Adult; Aged; Brachial Artery; Brain Injuries; Bronchial Spasm; Carotid Arteries; Cerebral Angiography; Child; Child, Preschool; Contrast Media; Female; Humans; Hypersensitivity; Infant; Infant, Newborn; Injections, Intra-Arterial; Iothalamate Meglumine; Male; Middle Aged; Pneumoencephalography; Respiration Disorders; Thrombosis