iothalamate-meglumine and Hypercalcemia

Six mediastinal parathyroid adenomas were stained by infusing contrast agent through a catheter wedged in the feeding artery. Adenomas in the first three cases were stained unintentionally with small volumes of dilute contrast media and hypercalcemia recurred within 3 to 6 months. In the next three patients, adenomas were deliberately stained with larger doses of concentrated contrast media and these patients have remained normocalcemic from 2 to 18 months following staining. The permanency of parathyroid ablation following deliberate staining with contrast media has not been established.

Topics: Adenoma; Adult; Aged; Angiography; Catheterization; Female; Humans; Hypercalcemia; Iothalamate Meglumine; Male; Mediastinal Neoplasms; Middle Aged; Parathyroid Neoplasms