iothalamate-meglumine and Adenocarcinoma

Demonstration of an air-fluid level in the body wall on a computed tomography examination usually suggests the presence of an abscess or a postoperative fluid collection. However, the small amount of air that frequently is injected during intravenous contrast administration may result in a similar computed tomography appearance.

Topics: Abscess; Adenocarcinoma; Adult; Axillary Vein; Breast Neoplasms; Diagnosis, Differential; Humans; Iothalamate Meglumine; Lymphatic Metastasis; Male; Mastectomy, Modified Radical; Postoperative Complications; Tomography, X-Ray Computed

An unusual case of iodide-induced thyrotoxicosis is documented in this article. The patient was a 64-year-old euthyroid man with acromegaly. He also had multiple follicular and papillary thyroid carcinomas with a metastatic lesion in the lumbar vertebrae. After a total thyroidectomy, he became slightly hypothyroid, and the lumbar lesion began to incorporate 131I by scintigraphy. When an iodine-containing contrast medium happened to be injected, a transient increase of serum thyroid hormone level was observed. After complete thyroid ablation with 83 mCi of 131I, the oral administration of 100 mg of potassium iodide for 7 days induced a prominent increase of serum thyroid hormone level. These findings indicated that the metastatic thyroid carcinoma could produce excess thyroid hormone insofar as a sufficient amount of iodide was given. Although this is the first report of such a case, iodide-induced thyrotoxicosis may not be rare in patients with thyroid carcinomas because the Wolff-Chaikoff effect is thought to be lost, and the organic iodinating activity and lysosomal protease activity are well-preserved.

Topics: Acromegaly; Adenocarcinoma; Contrast Media; Iodine Radioisotopes; Iothalamate Meglumine; Neoplasms, Multiple Primary; Postoperative Complications; Radionuclide Imaging; Spinal Neoplasms; Thyroid Hormones; Thyroid Neoplasms; Thyrotoxicosis

Ten patients with malignant primary neoplasms of the ear and temporal bone were examined with high-resolution computed tomography (CT) and the results correlated with the operative findings. CT was found to be highly accurate in establishing the presence and extent of tumor and is recommended as the procedure of choice for preoperative treatment planning.

Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Ear Neoplasms; Female; Humans; Iothalamate Meglumine; Male; Middle Aged; Paraganglioma; Skull Neoplasms; Temporal Bone; Tomography, X-Ray Computed

Topics: Adenocarcinoma; Evaluation Studies as Topic; Female; Humans; Iothalamate Meglumine; Male; Pancreatic Neoplasms; Radiographic Image Enhancement; Tomography, X-Ray Computed