iopromide has been researched along with Carcinoma, Hepatocellular in 41 studies
iopromide: structure given in first source
iopromide : A dicarboxylic acid diamide that consists of N-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A water soluble x-ray contrast agent for intravascular administration.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To define the percentage of small (≤2 cm) hepatocellular carcinoma (HCC) nodules showing the diagnostic enhancement pattern at CEUS, computed tomography (CT), and gadobenate dimeglumine (Gd-BOPTA)-enhanced magnetic resonance (MR) imaging." | 3.79 | Evidence of diagnostic enhancement pattern in hepatocellular carcinoma nodules ≤2 cm according to the AASLD/EASL revised criteria. ( Angileri, R; Cabibbo, B; Cova, MA; De Paoli, L; Pizzolato, R; Quaia, E, 2013) |
| "9 months) in 52 patients with hepatocellular carcinoma (HCC): An emulsion of Lipiodol and epirubicin was injected as selectively as possible in a dosage proportional to liver function and tumour size." | 3.69 | [The chemoembolization of hepatocellular carcinoma: the computed tomographic findings and clinical results in prospective repetitive therapy]. ( Brambs, HJ; Claussen, CD; Dette, S; Dietz, K; Duda, SH; Geissler, F; Huppert, PE; Lauchart, W, 1994) |
| "In contrast, among patients with hepatocellular carcinoma, mean contrast enhancement in lesions in the arterial phase was significantly superior in group A compared with group B." | 2.69 | Detection of focal liver lesions at biphasic spiral CT: randomized double-blind study of the effect of iodine concentration in contrast materials. ( Balzer, J; Clauss, W; Felfe, R; Felix, R; Hänninen, EL; Pegios, W; Vogl, TJ, 2000) |
| "Accurate assessment of viability of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is important for therapy planning." | 1.40 | Parametric response mapping of dynamic CT as an imaging biomarker to distinguish viability of hepatocellular carcinoma treated with transcatheter arterial chemoembolization. ( Choi, SJ; Kim, HS; Kim, J; Lee, JM; Park, H; Seo, J, 2014) |
| "Although hepatocellular carcinoma (HCC) demonstrates characteristic hypervascularity, some HCCs have a hypovascular pattern on computed tomography (CT)." | 1.38 | Prognostic implications of tumor vascularity and its relationship to cytokeratin 19 expression in patients with hepatocellular carcinoma. ( Chung, GE; Jang, JJ; Kim, SH; Kim, YJ; Lee, HS; Lee, JH; Lee, JM; Lee, K; Myung, SJ; Suh, KS; Yoon, JH, 2012) |
| "Most patients with HCC have coexisting liver cirrhosis (LC) at the time of diagnosis." | 1.37 | Incidence and risk factors for radiocontrast-induced nephropathy in patients with hepatocellular carcinoma undergoing transcatheter arterial chemoembolization. ( Bae, EJ; Chang, SH; Cho, HS; Kang, Y; Kim, HJ; Park, DJ; Seo, JW, 2011) |
| "In 20 patients with hepatocellular carcinomas, multiphasic liver CT scans including arterial, portal, and equilibrium phases were performed." | 1.36 | Image fusion in dual energy computed tomography for detection of hypervascular liver hepatocellular carcinoma: phantom and preliminary studies. ( Cho, SH; Choi, BI; Han, JK; Kim, KS; Kim, KW; Kim, SH; Kim, SJ; Lee, JM, 2010) |
| "Fifteen patients with either hepatocellular carcinoma (HCC, n = 8) or hypervascular liver metastases from uveal melanoma (n = 7) underwent arterial and portal venous C-arm CT of the liver using intraarterial contrast media administration directly before TACE." | 1.35 | Visualization of hypervascular liver lesions During TACE: comparison of angiographic C-arm CT and MDCT. ( Borchert, M; Frericks, BB; Justiz, J; Martus, P; Meyer, BC; Voges, M; Wacker, FK; Wolf, KJ, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (9.76) | 18.2507 |
| 2000's | 9 (21.95) | 29.6817 |
| 2010's | 27 (65.85) | 24.3611 |
| 2020's | 1 (2.44) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, HT | 1 |
| Shan, QY | 1 |
| Chen, SL | 1 |
| Li, B | 1 |
| Feng, ST | 1 |
| Xu, EJ | 1 |
| Li, X | 1 |
| Long, JY | 1 |
| Xie, XY | 1 |
| Lu, MD | 1 |
| Kuang, M | 1 |
| Shen, JX | 1 |
| Wang, W | 1 |
| Jia, GS | 1 |
| Feng, GL | 1 |
| Li, JP | 1 |
| Xu, HL | 1 |
| Wang, H | 2 |
| Cheng, YP | 1 |
| Yan, LL | 1 |
| Jiang, HJ | 1 |
| Lin, EY | 1 |
| Lee, RC | 1 |
| Guo, WY | 1 |
| Wu, FC | 1 |
| Gehrisch, S | 1 |
| Kowarschik, M | 1 |
| Zhang, L | 1 |
| Wang, N | 1 |
| Mao, J | 1 |
| Liu, X | 1 |
| Gao, Z | 1 |
| Dai, X | 1 |
| Feng, B | 1 |
| Woo, S | 2 |
| Lee, JM | 5 |
| Yoon, JH | 4 |
| Joo, I | 1 |
| Kim, SH | 4 |
| Lee, JY | 1 |
| Kim, YJ | 3 |
| Han, JK | 3 |
| Choi, BI | 3 |
| Chung, JW | 3 |
| Hur, S | 2 |
| Joo, SM | 1 |
| Kim, HC | 2 |
| Jae, HJ | 2 |
| Park, JH | 2 |
| Yu, MH | 1 |
| Baek, JH | 1 |
| Flohr, TG | 1 |
| Quaia, E | 1 |
| De Paoli, L | 1 |
| Angileri, R | 1 |
| Pizzolato, R | 1 |
| Cabibbo, B | 1 |
| Cova, MA | 1 |
| Kim, KA | 1 |
| Kim, MJ | 3 |
| Choi, JY | 1 |
| Park, MS | 2 |
| Lim, JS | 1 |
| Chung, YE | 1 |
| Kim, KW | 2 |
| Choi, SJ | 1 |
| Kim, J | 1 |
| Seo, J | 1 |
| Kim, HS | 1 |
| Park, H | 1 |
| Tan, B | 1 |
| Zhao, B | 1 |
| Gong, G | 1 |
| Xu, Z | 1 |
| Hoffmann, R | 1 |
| Rempp, H | 1 |
| Syha, R | 1 |
| Ketelsen, D | 1 |
| Pereira, PL | 2 |
| Claussen, CD | 3 |
| Clasen, S | 1 |
| Kaufmann, S | 2 |
| Schulze, M | 2 |
| Spira, D | 1 |
| Horger, M | 2 |
| Horger, T | 1 |
| Oelker, A | 1 |
| Nikolaou, K | 1 |
| Li, R | 1 |
| Cai, P | 1 |
| Ma, KS | 1 |
| Ding, SY | 1 |
| Guo, DY | 1 |
| Yan, XC | 1 |
| Zhou, Y | 1 |
| He, L | 1 |
| Huang, Y | 1 |
| Chen, S | 1 |
| Wu, P | 1 |
| Ye, W | 1 |
| Liu, Z | 1 |
| Liang, C | 1 |
| Choi, JW | 1 |
| Lee, JH | 2 |
| Yu, SJ | 1 |
| Cho, EJ | 1 |
| Kim, MU | 1 |
| Lee, M | 1 |
| Kim, EY | 1 |
| Choi, D | 5 |
| Lim, DH | 1 |
| Lee, WJ | 2 |
| Yoo, BC | 1 |
| Paik, SW | 1 |
| Balci, NC | 1 |
| Befeler, AS | 1 |
| Bieneman, BK | 1 |
| Fattahi, R | 1 |
| Saglam, S | 1 |
| Havlioglu, N | 1 |
| Park, Y | 1 |
| Kim, YS | 4 |
| Rhim, H | 4 |
| Lim, HK | 4 |
| Choi, JI | 1 |
| Choi, HJ | 1 |
| Jung, DC | 1 |
| Hong, EK | 1 |
| Park, JW | 1 |
| Jang, YJ | 1 |
| Kim, CM | 1 |
| Kim, KS | 1 |
| Kim, SJ | 1 |
| Cho, SH | 1 |
| Kim, JH | 1 |
| Yoon, HK | 1 |
| Ko, GY | 1 |
| Gwon, DI | 1 |
| Jang, CS | 1 |
| Song, HY | 1 |
| Shin, JH | 1 |
| Sung, KB | 1 |
| Kim, JE | 1 |
| Lee, MW | 3 |
| Shin, SW | 1 |
| Cho, SK | 1 |
| Chung, GE | 1 |
| Myung, SJ | 1 |
| Lee, K | 1 |
| Jang, JJ | 1 |
| Suh, KS | 1 |
| Lee, HS | 1 |
| Cho, HS | 1 |
| Seo, JW | 1 |
| Kang, Y | 1 |
| Bae, EJ | 1 |
| Kim, HJ | 1 |
| Chang, SH | 1 |
| Park, DJ | 1 |
| Yuan, Z | 1 |
| Ye, XD | 1 |
| Dong, S | 1 |
| Xu, LC | 1 |
| Xiao, XS | 1 |
| Cha, DI | 1 |
| Chung, WS | 1 |
| Lee, KH | 1 |
| Lee, YJ | 1 |
| Kwon, J | 1 |
| Baek, SE | 1 |
| Bova, V | 1 |
| Miraglia, R | 1 |
| Maruzzelli, L | 1 |
| Vizzini, GB | 1 |
| Luca, A | 1 |
| Lee, HY | 1 |
| Park, MJ | 1 |
| Kim, YK | 1 |
| Choi, YA | 1 |
| Kim, CK | 1 |
| Park, BK | 1 |
| Kim, B | 1 |
| Lin, J | 1 |
| Zhou, KR | 1 |
| Chen, ZW | 1 |
| Wang, JH | 1 |
| Yan, ZP | 1 |
| Wang, YX | 1 |
| Song, SY | 1 |
| Lim, HG | 1 |
| Meyer, BC | 1 |
| Frericks, BB | 1 |
| Voges, M | 1 |
| Borchert, M | 1 |
| Martus, P | 1 |
| Justiz, J | 1 |
| Wolf, KJ | 1 |
| Wacker, FK | 1 |
| Huppert, PE | 1 |
| Geissler, F | 1 |
| Duda, SH | 1 |
| Lauchart, W | 1 |
| Dette, S | 1 |
| Dietz, K | 1 |
| Brambs, HJ | 1 |
| Pacella, CM | 1 |
| Bizzarri, G | 1 |
| Anelli, V | 1 |
| Valle, D | 1 |
| Fabbrini, R | 1 |
| Bianchini, A | 1 |
| Fenderico, P | 1 |
| Rossi, Z | 1 |
| Luboldt, W | 1 |
| Straub, J | 1 |
| Seemann, M | 1 |
| Helmberger, T | 1 |
| Reiser, M | 1 |
| Kopka, L | 1 |
| Grabbe, E | 1 |
| Hänninen, EL | 1 |
| Vogl, TJ | 1 |
| Felfe, R | 1 |
| Pegios, W | 1 |
| Balzer, J | 1 |
| Clauss, W | 1 |
| Felix, R | 1 |
| Mehnert, F | 1 |
| Trübenbach, J | 1 |
| Kopp, AF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Artificial Intelligent Prognostic Assessment and Pathological Basis Research of Early Primary Hepatocellular Carcinoma After Minimally Invasive Treatment Based on Multimodal MRI and Clinical Big Data[NCT04299919] | 1,200 participants (Anticipated) | Observational | 2007-04-01 | Active, not recruiting | |||
| Recurrence Risk Factors of Early-Stage Hepatocellular Carcinoma After Radio Frequency Ablation: a Multi-center Prospective Case-control Study[NCT02046356] | 139 participants (Actual) | Observational [Patient Registry] | 2014-01-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for iopromide and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
CT findings of primary clear cell carcinoma of liver: with analysis of 19 cases and review of the literature.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Contrast Media; Diagnosis, Differential; Female; Humans; Ioh | 2014 |
3 trials available for iopromide and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Change in contrast enhancement of HCC on 1-month follow-up CT after local radiotherapy: an early predictor of final treatment response.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Contrast Media; Female; Humans; Iohexol; | 2009 |
Detection of focal liver lesions at biphasic spiral CT: randomized double-blind study of the effect of iodine concentration in contrast materials.
Topics: Adult; Aged; Aged, 80 and over; Aorta; Carcinoma, Hepatocellular; Contrast Media; Double-Blind Metho | 2000 |
Biphasic spiral CT of the liver: automatic bolus tracking or time delay?
Topics: Adult; Aged; Carcinoma, Hepatocellular; Contrast Media; Female; Humans; Image Processing, Computer-A | 2001 |
37 other studies available for iopromide and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
CT-based radiomics for preoperative prediction of early recurrent hepatocellular carcinoma: technical reproducibility of acquisition and scanners.
Topics: Adult; Aged; Algorithms; Biomarkers, Tumor; Carcinoma, Hepatocellular; Contrast Media; Female; Hepat | 2020 |
Using receiver operating characteristic curves to evaluate the diagnostic value of the combination of multislice spiral CT and alpha-fetoprotein levels for small hepatocellular carcinoma in cirrhotic patients.
Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Carcinoma, Hepatocellular; Case-Control Studies; C | 2017 |
Three-Dimensional Quantitative Color-Coding Analysis of Hepatic Arterial Flow Change during Chemoembolization of Hepatocellular Carcinoma.
Topics: Aged; Aged, 80 and over; Angiography; Angiography, Digital Subtraction; Blood Flow Velocity; Carcino | 2018 |
Dual-Energy CT-Derived Volumetric Iodine Concentration for the Assessment of Therapeutic Response after Microwave Ablation in a Rabbit Model with Intrahepatic VX2 Tumor.
Topics: Ablation Techniques; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Contrast Media; Iohexol; | 2018 |
Small- and medium-sized hepatocellular carcinomas: monopolar radiofrequency ablation with a multiple-electrode switching system-mid-term results.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Catheter Ablation; Contrast Media; Female | 2013 |
Liver abscess after transarterial chemoembolization in patients with bilioenteric anastomosis: frequency and risk factors.
Topics: Adult; Aged; Anastomosis, Surgical; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Contr | 2013 |
Low tube voltage intermediate tube current liver MDCT: sinogram-affirmed iterative reconstruction algorithm for detection of hypervascular hepatocellular carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Analysis of Variance; Carcinoma, Hepatocellular; Contras | 2013 |
Evidence of diagnostic enhancement pattern in hepatocellular carcinoma nodules ≤2 cm according to the AASLD/EASL revised criteria.
Topics: Aged; Biopsy; Carcinoma, Hepatocellular; Contrast Media; Diagnosis, Differential; Female; Humans; Im | 2013 |
Detection of recurrent hepatocellular carcinoma on post-operative surveillance: comparison of MDCT and gadoxetic acid-enhanced MRI.
Topics: Aged; Carcinoma, Hepatocellular; Contrast Media; Female; Gadolinium DTPA; Humans; Iohexol; Liver Neo | 2014 |
Parametric response mapping of dynamic CT as an imaging biomarker to distinguish viability of hepatocellular carcinoma treated with transcatheter arterial chemoembolization.
Topics: Aged; Area Under Curve; Biomarkers, Tumor; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic | 2014 |
Transarterial chemoembolization using drug eluting beads and subsequent percutaneous MR-guided radiofrequency ablation in the therapy of intermediate sized hepatocellular carcinoma.
Topics: Aged; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Catheter Ablation; Chemoembolization, | 2014 |
Comparison of volume perfusion computed tomography and contrast-enhanced ultrasound for assessment of therapeutic effect of transarterial chemoembolization in patients with hepatocellular carcinoma: a preliminary report.
Topics: Aged; Aged, 80 and over; Blood Volume; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Co | 2016 |
Reproducibility of VPCT parameters in the normal pancreas: comparison of two different kinetic calculation models.
Topics: Adult; Aged; Blood Volume; Carcinoma, Hepatocellular; Cone-Beam Computed Tomography; Contrast Media; | 2015 |
Dynamic enhancement patterns of intrahepatic cholangiocarcinoma in cirrhosis on contrast-enhanced computed tomography: risk of misdiagnosis as hepatocellular carcinoma.
Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cholangiocarcinoma; Contrast Media; Diagn | 2016 |
CT-based radiomics signature: a potential biomarker for preoperative prediction of early recurrence in hepatocellular carcinoma.
Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Hepatocellular; Contrast Media; Female; Hepatectomy; Huma | 2017 |
Cone Beam CT-Guided Chemoembolization of Probable Hepatocellular Carcinomas Smaller than 1 cm in Patients at High Risk of Hepatocellular Carcinoma.
Topics: Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cone-Beam Computed Tomography; Contrast M | 2017 |
Fat containing HCC: findings on CT and MRI including serial contrast-enhanced imaging.
Topics: Adipose Tissue; Adult; Aged; Carcinoma, Hepatocellular; Contrast Media; Female; Gadolinium DTPA; Hum | 2009 |
Arterial enhancement of hepatocellular carcinoma before radiofrequency ablation as a predictor of postablation local tumor progression.
Topics: Aged; Arteries; Carcinoma, Hepatocellular; Catheter Ablation; Contrast Media; Disease Progression; F | 2009 |
Diagnostic value of early-phase-enhanced computed tomography for the differentiation of pulmonary metastases from hepatocellular carcinoma and primary lung cancer.
Topics: Adolescent; Adult; Aged; Carcinoma, Hepatocellular; Contrast Media; Diagnosis, Differential; Female; | 2009 |
Image fusion in dual energy computed tomography for detection of hypervascular liver hepatocellular carcinoma: phantom and preliminary studies.
Topics: Adult; Aged; Analysis of Variance; Carcinoma, Hepatocellular; Contrast Media; Female; Humans; Iohexo | 2010 |
Nonresectable combined hepatocellular carcinoma and cholangiocarcinoma: analysis of the response and prognostic factors after transcatheter arterial chemoembolization.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cholangiocarcinoma; Cisplati | 2010 |
Outcomes of patients with hepatocellular carcinoma referred for percutaneous radiofrequency ablation at a tertiary center: analysis focused on the feasibility with the use of ultrasonography guidance.
Topics: Adult; Aged; Aged, 80 and over; Biopsy, Needle; Carcinoma, Hepatocellular; Catheter Ablation; Contra | 2011 |
Prognostic implications of tumor vascularity and its relationship to cytokeratin 19 expression in patients with hepatocellular carcinoma.
Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Chi-Square Distribution; Contrast Media; Female; Human | 2012 |
Incidence and risk factors for radiocontrast-induced nephropathy in patients with hepatocellular carcinoma undergoing transcatheter arterial chemoembolization.
Topics: Acute Kidney Injury; Aged; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Contrast Media | 2011 |
Evaluation of early imaging response after chemoembolization of hepatocellular carcinoma by phosphorus-31 magnetic resonance spectroscopy-initial experience.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Contrast Media; Ethiodized O | 2011 |
Percutaneous radiofrequency ablation of hepatocellular carcinoma: fusion imaging guidance for management of lesions with poor conspicuity at conventional sonography.
Topics: Carcinoma, Hepatocellular; Catheter Ablation; Contrast Media; Female; Humans; Image Enhancement; Ima | 2012 |
Enhancement patterns of hepatocellular carcinoma after transarterial chemoembolization using drug-eluting beads on arterial phase CT images: a pilot retrospective study.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; | 2012 |
Predictive factors of downstaging of hepatocellular carcinoma beyond the Milan criteria treated with intra-arterial therapies.
Topics: Adult; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Chi-Square Distribution; Contrast | 2013 |
Early diffuse recurrence of hepatocellular carcinoma after percutaneous radiofrequency ablation: analysis of risk factors.
Topics: Aged; Biopsy; Carcinoma, Hepatocellular; Case-Control Studies; Catheter Ablation; Contrast Media; Di | 2013 |
Evaluation of adrenal metastases from renal cell carcinoma and hepatocellular carcinoma: use of delayed contrast-enhanced CT.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Contrast Med | 2013 |
3D contrast-enhanced MR portography and direct X-ray portography: a correlation study.
Topics: Adult; Carcinoma, Hepatocellular; Contrast Media; Female; Gadolinium DTPA; Humans; Hypertension, Por | 2003 |
Nonhepatic arteries originating from the hepatic arteries: angiographic analysis in 250 patients.
Topics: Adult; Aged; Aged, 80 and over; Angiography; Angiography, Digital Subtraction; Carcinoma, Hepatocell | 2006 |
Visualization of hypervascular liver lesions During TACE: comparison of angiographic C-arm CT and MDCT.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Contrast Media; Diagnosis, D | 2008 |
[The chemoembolization of hepatocellular carcinoma: the computed tomographic findings and clinical results in prospective repetitive therapy].
Topics: Adult; Aged; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Clinical Protocols; Contrast | 1994 |
Evaluation of the vascular pattern of hepatocellular carcinoma with dynamic computed tomography and its use in identifying optimal temporal windows for helical computed tomography.
Topics: Aged; Aorta, Abdominal; Carcinoma, Hepatocellular; Contrast Media; Evaluation Studies as Topic; Fema | 1998 |
Effective contrast use in CT angiography and dual-phase hepatic CT performed with a subsecond scanner.
Topics: Angiography; Carcinoma, Hepatocellular; Contrast Media; Female; Hemangioma; Humans; Injections, Intr | 1999 |
[Biphasic liver diagnosis with multiplanar-detector spiral CT].
Topics: Adult; Carcinoma, Hepatocellular; Contrast Media; Female; Humans; Iohexol; Liver; Liver Neoplasms; M | 1999 |