Page last updated: 2024-10-29

iomeprol and Coronary Stenosis

iomeprol has been researched along with Coronary Stenosis in 29 studies

iomeprol: structure given in first source
iomeprol : A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a glycoloyl(methyl)amino group at the 5-position.

Coronary Stenosis: Narrowing or constriction of a coronary artery.

Research Excerpts

ExcerptRelevanceReference
"CCO decrease across coronary stenosis is associated with myocardial ischemia on APMR."5.42Hemodynamic significance of coronary stenosis by vessel attenuation measurement on CT compared with adenosine perfusion MRI. ( den Dekker, MAM; Oudkerk, M; Pelgrim, GJ; Pundziute, G; van den Heuvel, ER; Vliegenthart, R, 2015)
"With current CT technology, iobitridol 350 mg iodine/ml is not inferior to contrast media with higher iodine concentrations in terms of image quality for coronary stenosis assessment."5.24Comparative assessment of image quality for coronary CT angiography with iobitridol and two contrast agents with higher iodine concentrations: iopromide and iomeprol. A multicentre randomized double-blind trial. ( Achenbach, S; Andreu, J; Becker, HC; Benea, G; Cabeza, B; Cademartiri, F; Caudron, J; Jacquier, A; Knobloch, G; Laurent, F; Leschka, S; Paul, JF; Qanadli, SD; Rengo, M; Revel, D; Schlosser, T; Souto, M; Vignaux, O, 2017)
"Eighty patients with 104 intermediate coronary stenoses were prospectively and consecutively enrolled."1.42Efficacy of contrast medium induced Pd/Pa ratio in predicting functional significance of intermediate coronary artery stenosis assessed by fractional flow reserve: insights from the RINASCI study. ( Aurigemma, C; Basile, E; Burzotta, F; Cialdella, P; Clemente, F; Crea, F; De Caterina, AR; De Maria, GL; Gardi, A; Leone, AM; Niccoli, G; Porto, I; Rebuzzi, AG; Scalone, G; Tagliaferro, F; Trani, C, 2015)
"CCO decrease across coronary stenosis is associated with myocardial ischemia on APMR."1.42Hemodynamic significance of coronary stenosis by vessel attenuation measurement on CT compared with adenosine perfusion MRI. ( den Dekker, MAM; Oudkerk, M; Pelgrim, GJ; Pundziute, G; van den Heuvel, ER; Vliegenthart, R, 2015)
"Sensitivity and specificity were 94."1.36Role of 64-slice cardiac computed tomography in the evaluation of patients with non-ST-elevation acute coronary syndrome. ( Acampora, V; Arganini, C; Bazzocchi, G; De Angelis, B; Martuscelli, E; Patrei, A; Romagnoli, A; Romeo, F; Simonetti, G; Sperandio, M, 2010)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (37.93)29.6817
2010's18 (62.07)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ochs, MM1
Andre, F1
Korosoglou, G1
Fritz, T1
Seitz, S1
Bogomazov, Y1
Schlett, CL1
Sokiranski, R1
Sommer, A1
Gückel, F1
Brado, M1
Kauczor, HU1
Görich, J1
Katus, HA1
Buss, SJ1
Cerrato, E1
Tomassini, F1
Salinas, P1
Pavani, M1
Conrotto, F1
Echavarria-Pinto, M1
Macaya, F1
Quadri, G1
D'Ascenzo, F1
Quirós, A1
Varbella, F1
Escaned, J1
Huber, AM1
Leber, V1
Gramer, BM1
Muenzel, D1
Leber, A1
Rieber, J1
Schmidt, M1
Vembar, M1
Hoffmann, E1
Rummeny, E1
Vogler, N1
Meyer, M1
Fink, C1
Schoepf, UJ1
Schönberg, SO1
Henzler, T1
Park, JJ1
Chun, EJ3
Cho, YS1
Oh, IY1
Yoon, CH1
Suh, JW1
Choi, SI3
Youn, TJ1
Koo, BK1
Chae, IH1
Choi, DJ2
Leone, AM1
Scalone, G1
De Maria, GL1
Tagliaferro, F1
Gardi, A1
Clemente, F1
Basile, E1
Cialdella, P1
De Caterina, AR1
Porto, I1
Aurigemma, C1
Burzotta, F1
Niccoli, G1
Trani, C1
Rebuzzi, AG1
Crea, F1
den Dekker, MAM1
Pelgrim, GJ1
Pundziute, G1
van den Heuvel, ER1
Oudkerk, M1
Vliegenthart, R1
Ko, BS1
Wong, DT1
Nørgaard, BL1
Leong, DP1
Cameron, JD1
Gaur, S1
Marwan, M1
Achenbach, S2
Kuribayashi, S1
Kimura, T1
Meredith, IT1
Seneviratne, SK1
Paul, JF1
Laurent, F1
Becker, HC1
Rengo, M1
Caudron, J1
Leschka, S1
Vignaux, O1
Knobloch, G1
Benea, G1
Schlosser, T1
Andreu, J1
Cabeza, B1
Jacquier, A1
Souto, M1
Revel, D1
Qanadli, SD1
Cademartiri, F6
Wilhelmi, M1
Gasser, S1
Reimann, AJ2
Tsiflikas, I3
Brodoefel, H3
Scheuering, M1
Rinck, D1
Kopp, AF4
Claussen, CD4
Heuschmid, M4
Krug, KB1
Bovenschulte, H2
Geissler, HJ1
Flesch, M1
Schneider, T2
Brackrogge, D1
Reiter, H1
Heppelmann, I1
Christ, H1
Fischer, JH1
Lackner, KJ1
Steppich, BA1
Kaufmann, J1
Sepp, D1
Kunert, K1
Rutz, T1
Stratz, C1
Ott, I1
Romagnoli, A1
Martuscelli, E1
Sperandio, M1
Arganini, C1
De Angelis, B1
Acampora, V1
Patrei, A1
Bazzocchi, G1
Romeo, F1
Simonetti, G1
van Velzen, JE1
Schuijf, JD2
van Werkhoven, JM1
Herzog, BA1
Pazhenkottil, AP1
Boersma, E1
de Graaf, FR1
Scholte, AJ1
Kroft, LJ2
de Roos, A2
Stokkel, MP1
Jukema, JW1
Kaufmann, PA1
van der Wall, EE1
Bax, JJ2
Maffei, E4
Palumbo, A3
Martini, C2
Ugo, F2
Lina, D2
Aldrovandi, A4
Reverberi, C2
Manca, C1
Ardissino, D2
Crisi, G1
Hadamitzky, M1
Distler, R1
Meyer, T1
Hein, F1
Kastrati, A1
Martinoff, S1
Schömig, A1
Hausleiter, J1
van der Bijl, N1
Joemai, RM1
Geleijns, J1
Lim, S1
Shin, H1
Lee, Y1
Yoon, JW1
Kang, SM1
Choi, SH1
Park, KS1
Jang, HC1
Rossi, A1
Mollet, N2
Lario, C1
Castiglione Morelli, M1
Clemente, A1
Gentile, G1
Arcadi, T1
Seitun, S1
Catalano, O1
Yoo, DH1
Kim, JA1
Jin, KN1
Yeon, TJ1
Krug, B1
Schwabe, H1
Kabbasch, C1
Bangard, C1
Hellmich, M1
Michels, G1
Maintz, D1
Lackner, K1
Marano, R1
Luccichenti, G1
Runza, G2
Galia, M1
Belgrano, M1
Gualerzi, M1
Brambilla, L1
Coruzzi, P1
Midiri, M3
Andreini, D1
Pontone, G1
Pepi, M1
Ballerini, G1
Bartorelli, AL1
Magini, A1
Quaglia, C1
Nobili, E1
Agostoni, P1
Reimann, A2
Burgstahler, C3
Schumacher, F2
Herberts, T1
Schroeder, S2
Kuettner, A1
Klumpp, B1
Teufel, M1
Beck, T1
Schröder, S1
Malagò, R2
Alberghina, F1
Brambilla, V1
La Grutta, L1
Menozzi, A2
Vignali, L2
Casolo, G1
Mollet, NR2
Notarangelo, F1
Solinas, E1
Cervellin, G1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
HeartFlowNXT - HeartFlow Analysis of Coronary Blood Flow Using Coronary CT Angiography: NeXt sTeps[NCT01757678]276 participants (Actual)Interventional2012-09-30Completed
Artificial Intelligence for Preventing Heart Disease: Observational, Single Center, Prospective and Retrospective Study[NCT06029387]3,000 participants (Anticipated)Observational2023-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

AUC of FFRct Versus Coronary CTA for Demonstration of Ischemia (≤0.80) on a Per-patient Basis

The primary statistical measure will be the area under the receiver operating characteristic curve (AUC of ROC) of a patient-based model to detect hemodynamically significant obstruction. ROC graphs the change in sensitivity as the cut-point for positive/negative diagnosis moves from its lower to upper limit. FFR is used as the reference standard to determine the presence or absence of hemodynamic obstruction. For FFR, hemodynamically-significant obstruction of a coronary artery is defined as an FFR≤0.80 in any major epicardial coronary artery segment with diameter ≥2.0 mm during adenosine-mediated hyperemia. For cCTA, hemodynamically-significant obstruction of a coronary artery is defined as a stenosis >50% . FFRCT will be calculated for each patient as the minimum FFRCT in any coronary artery segment . cCTA stenosis will be calculated for each patient as the highest cCTA stenosis category for any vessel all measurements will take place only in segments with diameter ≥2.0 mm. (NCT01757678)
Timeframe: 1 day; Outcome measures were comparing FFRct to FFR. Incident time for FFR was dependent on the length of time on the cath procedure. FFRct was done remotely at HeartFlow's processing center in Redwood City with a turnaround time of 24 hours from CT scan.

Interventionprobablility (Number)
FFRct vs. FFR.90
cCTA vs. FFR.81

AUC of FFRct Versus Coronary CTA for Demonstration of Ischemia (≤0.80) on a Per-vessel Basis

(NCT01757678)
Timeframe: 1 day

Interventionprobability (Number)
FFRct vs. FFR.93
cCTA vs. FFR.79

Per Vessel Diagnostic Performance of FFRct, Coronary CTA, and ICA

(NCT01757678)
Timeframe: 1 day; Outcome measures were comparing FFRct to FFR. Incident time for FFR was dependent on the length of time on the cath procedure. FFRct was done remotely at HeartFlow's processing center in Redwood City with a turnaround time of 24 hours from CT scan.

Interventionpercentage of tests (Number)
Accuracy: ICA Stenosis >50%Accuracy: FFRct ≤ 0.80Accuracy: Coronary CTA Stenosis >50%Sensitivity: ICA Stenosis >50%Sensitivity: FFRct ≤ 0.80Sensitivity: Coronary CTA Stenosis >50%Specificity: ICA Stenosis >50%Specificity: FFRct ≤ 0.80Specificity: Coronary CTA Stenosis >50%Positive Predictive Value: ICA Stenosis >50%Positive Predictive Value: FFRct ≤ 0.80Positive Predictive Value: cCTA Stenosis >50%Negative Predictive Value: ICA Stenosis >50%Negative Predictive Value: FFRct ≤ 0.80Negative Predictive Value: cCTA Stenosis >50%
Standard of Care: FFR and ICA828665558483908660586133889592

Per-Patient Analysis: Diagnostic Performance of FFRct, Coronary CTA, and ICA

(NCT01757678)
Timeframe: 1 day; Outcome measures were comparing FFRct to FFR. Incident time for FFR was dependent on the length of time on the cath procedure. FFRct was done remotely at HeartFlow's processing center in Redwood City with a turnaround time of 24 hours from CT scan.

Interventionpercentage of tests (Number)
Accuracy: ICA Stenosis >50%Accuracy: FFRct ≤ 0.80Accuracy: Coronary CTA Stenosis >50%Sensitivity: ICA Stenosis >50%Sensitivity: FFRct ≤ 0.80Sensitivity: Coronary CTA Stenosis >50%Specificity: ICA Stenosis >50%Specificity: FFRct ≤ 0.80Specificity: Coronary CTA Stenosis >50%Positive Predictive Value: ICA Stenosis >50%Positive Predictive Value: FFRct ≤ 0.80Positive Predictive Value: cCTA Stenosis >50%Negative Predictive Value: ICA Stenosis >50%Negative Predictive Value: FFRct ≤ 0.80Negative Predictive Value: cCTA Stenosis >50%
Standard of Care: FFR and ICA778153648694837934636540839392

Per-Patient Diagnostic Performance of FFRct in Patients With Intermediate Stenosis Severity (30%-70%) According to Coronary CTA

(NCT01757678)
Timeframe: 1 day; Outcome measures were comparing FFRct to FFR. Incident time for FFR was dependent on the length of time on the cath procedure. FFRct was done remotely at HeartFlow's processing center in Redwood City with a turnaround time of 24 hours from CT scan.

Interventionpercentage of tests (Number)
Accuracy: FFRct ≤ 0.80Accuracy: Coronary CTA Stenosis > 50%Sensitivity: FFRct ≤ 0.80Sensitivity: Coronary CTA Stenosis >50%Specificity: FFRct ≤ 0.80Specificity: Coronary CTA Stenosis > 50%Positive Predictive Value: FFRct ≤ 0.80Positive Predictive Value: cCTA Stenosis > 50%Negative Predictive Value: FFRct ≤ 0.80Negative Predictive Value: cCTA Stenosis > 50%
Standard of Care: FFR and ICA80518593793263379291

Trials

3 trials available for iomeprol and Coronary Stenosis

ArticleYear
Comparative assessment of image quality for coronary CT angiography with iobitridol and two contrast agents with higher iodine concentrations: iopromide and iomeprol. A multicentre randomized double-blind trial.
    European radiology, 2017, Volume: 27, Issue:2

    Topics: Adult; Aged; Calcinosis; Computed Tomography Angiography; Contrast Media; Coronary Angiography; Coro

2017
Diagnostic accuracy of computed tomography coronary angiography in a high risk symptomatic population.
    Acta bio-medica : Atenei Parmensis, 2010, Volume: 81, Issue:1

    Topics: Aged; Cohort Studies; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Humans; Iopam

2010
Diagnostic accuracy of multidetector computed tomography coronary angiography in patients with dilated cardiomyopathy.
    Journal of the American College of Cardiology, 2007, May-22, Volume: 49, Issue:20

    Topics: Artifacts; Cardiomyopathy, Dilated; Contrast Media; Coronary Angiography; Coronary Artery Disease; C

2007

Other Studies

26 other studies available for iomeprol and Coronary Stenosis

ArticleYear
Strengths and limitations of coronary angiography with turbo high-pitch third-generation dual-source CT.
    Clinical radiology, 2017, Volume: 72, Issue:9

    Topics: Aged; Cardiac-Gated Imaging Techniques; Computed Tomography Angiography; Contrast Media; Coronary An

2017
Simplified hybrid algorithms for pressure wire interrogation exploiting advantages of a baseline and contrast Pd/Pa ratio indexes to predict stenosis significance: Insight from the SPARE multicenter prospective study.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2018, 11-15, Volume: 92, Issue:6

    Topics: Adenosine; Aged; Algorithms; Cardiac Catheterization; Cardiac Catheters; Clinical Decision-Making; C

2018
Myocardium: dynamic versus single-shot CT perfusion imaging.
    Radiology, 2013, Volume: 269, Issue:2

    Topics: Aged; Comorbidity; Contrast Media; Coronary Angiography; Coronary Stenosis; Exercise Test; Female; F

2013
Predictive value of zero calcium score and low-end percentiles for the presence of significant coronary artery stenosis in stable patients with suspected coronary artery disease.
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2013, Volume: 185, Issue:8

    Topics: Aged; Aged, 80 and over; Body Mass Index; Calcinosis; Cardiac Catheterization; Cardiac-Gated Imaging

2013
Potential predictors of side-branch occlusion in bifurcation lesions after percutaneous coronary intervention: a coronary CT angiography study.
    Radiology, 2014, Volume: 271, Issue:3

    Topics: Cardiac-Gated Imaging Techniques; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; H

2014
Efficacy of contrast medium induced Pd/Pa ratio in predicting functional significance of intermediate coronary artery stenosis assessed by fractional flow reserve: insights from the RINASCI study.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2015, Volume: 11, Issue:4

    Topics: Adenosine; Aged; Area Under Curve; Cardiac Catheterization; Contrast Media; Coronary Angiography; Co

2015
Hemodynamic significance of coronary stenosis by vessel attenuation measurement on CT compared with adenosine perfusion MRI.
    European journal of radiology, 2015, Volume: 84, Issue:1

    Topics: Adenosine; Adult; Aged; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Hemodynamic

2015
Diagnostic Performance of Transluminal Attenuation Gradient and Noninvasive Fractional Flow Reserve Derived from 320-Detector Row CT Angiography to Diagnose Hemodynamically Significant Coronary Stenosis: An NXT Substudy.
    Radiology, 2016, Volume: 279, Issue:1

    Topics: Blood Flow Velocity; Cardiac-Gated Imaging Techniques; Contrast Media; Coronary Angiography; Coronar

2016
[Recurrent parotid enlargement following coronary angiography].
    Praxis, 2008, May-14, Volume: 97, Issue:10

    Topics: Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Coronary Stenosis; Diagnosis,

2008
Efficacy of computer aided analysis in detection of significant coronary artery stenosis in cardiac using dual source computed tomography.
    The international journal of cardiovascular imaging, 2009, Volume: 25, Issue:2

    Topics: Aged; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Humans; Imaging, Three-Dimens

2009
In-vivo measurements of coronary blood flow using 16-slice multidetector spiral computed tomography (MDCT) in a porcine model.
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2009, Volume: 181, Issue:3

    Topics: Animals; Blood Flow Velocity; Blood Volume; Contrast Media; Coronary Angiography; Coronary Circulati

2009
Increased circulating placental growth factor during percutaneous coronary intervention is associated with applied radiocontrast agent.
    Coronary artery disease, 2009, Volume: 20, Issue:2

    Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Anticoagulants; Biomarkers; Case-Control Studies; C

2009
Role of 64-slice cardiac computed tomography in the evaluation of patients with non-ST-elevation acute coronary syndrome.
    La Radiologia medica, 2010, Volume: 115, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Analysis of Variance; Chi-Square Distribution; Contrast Media; Corona

2010
Predictive value of multislice computed tomography variables of atherosclerosis for ischemia on stress-rest single-photon emission computed tomography.
    Circulation. Cardiovascular imaging, 2010, Volume: 3, Issue:6

    Topics: Atherosclerosis; Contrast Media; Coronary Angiography; Coronary Stenosis; Coronary Vessels; Exercise

2010
Prognostic value of coronary computed tomographic angiography in comparison with calcium scoring and clinical risk scores.
    Circulation. Cardiovascular imaging, 2011, Volume: 4, Issue:1

    Topics: Aged; Calcinosis; Contrast Media; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis;

2011
Assessment of Agatston coronary artery calcium score using contrast-enhanced CT coronary angiography.
    AJR. American journal of roentgenology, 2010, Volume: 195, Issue:6

    Topics: Calcinosis; Contrast Media; Coronary Angiography; Coronary Stenosis; Electrocardiography; Female; Hu

2010
Effect of metabolic syndrome on coronary artery stenosis and plaque characteristics as assessed with 64-detector row cardiac CT.
    Radiology, 2011, Volume: 261, Issue:2

    Topics: Adult; Aged; Anthropometry; Calcinosis; Chi-Square Distribution; Contrast Media; Coronary Artery Dis

2011
Diagnostic accuracy of second-generation dual-source computed tomography coronary angiography with iterative reconstructions: a real-world experience.
    La Radiologia medica, 2012, Volume: 117, Issue:5

    Topics: Algorithms; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Humans; Iopamidol; Like

2012
Significance of noncalcified coronary plaque in asymptomatic subjects with low coronary artery calcium score: assessment with coronary computed tomography angiography.
    The international journal of cardiovascular imaging, 2011, Volume: 27 Suppl 1

    Topics: Calcinosis; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Follow-Up Studies; Huma

2011
CT coronary angiography: coronary CT-flow quantification supplements morphological stenosis analysis.
    European journal of radiology, 2013, Volume: 82, Issue:4

    Topics: Aged; Blood Flow Velocity; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Humans;

2013
Image assessment with multislice CT coronary angiography.
    La Radiologia medica, 2005, Volume: 109, Issue:3

    Topics: Contrast Media; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Female; Humans; Im

2005
Noninvasive coronary angiography using 64-slice spiral computed tomography in an unselected patient collective: effect of heart rate, heart rate variability and coronary calcifications on image quality and diagnostic accuracy.
    European journal of radiology, 2008, Volume: 66, Issue:1

    Topics: Body Mass Index; Calcinosis; Chi-Square Distribution; Contrast Media; Coronary Angiography; Coronary

2008
Late enhancement using multidetector row computer tomography: a feasibility study with low dose 80 kV protocol.
    European journal of radiology, 2008, Volume: 66, Issue:1

    Topics: Adult; Aged; Contrast Media; Coronary Angiography; Coronary Stenosis; Feasibility Studies; Female; G

2008
Diagnostic accuracy of 64-slice computed tomography coronary angiography in patients with low-to-intermediate risk.
    La Radiologia medica, 2007, Volume: 112, Issue:7

    Topics: Algorithms; Chest Pain; Contrast Media; Coronary Angiography; Coronary Disease; Coronary Stenosis; D

2007
Dual-source CT: effect of heart rate, heart rate variability, and calcification on image quality and diagnostic accuracy.
    Radiology, 2008, Volume: 247, Issue:2

    Topics: Algorithms; Calcinosis; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Heart Rate;

2008
64-slice computed tomography coronary angiography: diagnostic accuracy in the real world.
    La Radiologia medica, 2008, Volume: 113, Issue:2

    Topics: Aged; Contrast Media; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Female; Huma

2008