iomeprol has been researched along with Coronary Stenosis in 29 studies
iomeprol: structure given in first source
iomeprol : A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a glycoloyl(methyl)amino group at the 5-position.
Coronary Stenosis: Narrowing or constriction of a coronary artery.
Excerpt | Relevance | Reference |
---|---|---|
"CCO decrease across coronary stenosis is associated with myocardial ischemia on APMR." | 5.42 | Hemodynamic significance of coronary stenosis by vessel attenuation measurement on CT compared with adenosine perfusion MRI. ( den Dekker, MAM; Oudkerk, M; Pelgrim, GJ; Pundziute, G; van den Heuvel, ER; Vliegenthart, R, 2015) |
"With current CT technology, iobitridol 350 mg iodine/ml is not inferior to contrast media with higher iodine concentrations in terms of image quality for coronary stenosis assessment." | 5.24 | Comparative assessment of image quality for coronary CT angiography with iobitridol and two contrast agents with higher iodine concentrations: iopromide and iomeprol. A multicentre randomized double-blind trial. ( Achenbach, S; Andreu, J; Becker, HC; Benea, G; Cabeza, B; Cademartiri, F; Caudron, J; Jacquier, A; Knobloch, G; Laurent, F; Leschka, S; Paul, JF; Qanadli, SD; Rengo, M; Revel, D; Schlosser, T; Souto, M; Vignaux, O, 2017) |
"Eighty patients with 104 intermediate coronary stenoses were prospectively and consecutively enrolled." | 1.42 | Efficacy of contrast medium induced Pd/Pa ratio in predicting functional significance of intermediate coronary artery stenosis assessed by fractional flow reserve: insights from the RINASCI study. ( Aurigemma, C; Basile, E; Burzotta, F; Cialdella, P; Clemente, F; Crea, F; De Caterina, AR; De Maria, GL; Gardi, A; Leone, AM; Niccoli, G; Porto, I; Rebuzzi, AG; Scalone, G; Tagliaferro, F; Trani, C, 2015) |
"CCO decrease across coronary stenosis is associated with myocardial ischemia on APMR." | 1.42 | Hemodynamic significance of coronary stenosis by vessel attenuation measurement on CT compared with adenosine perfusion MRI. ( den Dekker, MAM; Oudkerk, M; Pelgrim, GJ; Pundziute, G; van den Heuvel, ER; Vliegenthart, R, 2015) |
"Sensitivity and specificity were 94." | 1.36 | Role of 64-slice cardiac computed tomography in the evaluation of patients with non-ST-elevation acute coronary syndrome. ( Acampora, V; Arganini, C; Bazzocchi, G; De Angelis, B; Martuscelli, E; Patrei, A; Romagnoli, A; Romeo, F; Simonetti, G; Sperandio, M, 2010) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 11 (37.93) | 29.6817 |
2010's | 18 (62.07) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Ochs, MM | 1 |
Andre, F | 1 |
Korosoglou, G | 1 |
Fritz, T | 1 |
Seitz, S | 1 |
Bogomazov, Y | 1 |
Schlett, CL | 1 |
Sokiranski, R | 1 |
Sommer, A | 1 |
Gückel, F | 1 |
Brado, M | 1 |
Kauczor, HU | 1 |
Görich, J | 1 |
Katus, HA | 1 |
Buss, SJ | 1 |
Cerrato, E | 1 |
Tomassini, F | 1 |
Salinas, P | 1 |
Pavani, M | 1 |
Conrotto, F | 1 |
Echavarria-Pinto, M | 1 |
Macaya, F | 1 |
Quadri, G | 1 |
D'Ascenzo, F | 1 |
Quirós, A | 1 |
Varbella, F | 1 |
Escaned, J | 1 |
Huber, AM | 1 |
Leber, V | 1 |
Gramer, BM | 1 |
Muenzel, D | 1 |
Leber, A | 1 |
Rieber, J | 1 |
Schmidt, M | 1 |
Vembar, M | 1 |
Hoffmann, E | 1 |
Rummeny, E | 1 |
Vogler, N | 1 |
Meyer, M | 1 |
Fink, C | 1 |
Schoepf, UJ | 1 |
Schönberg, SO | 1 |
Henzler, T | 1 |
Park, JJ | 1 |
Chun, EJ | 3 |
Cho, YS | 1 |
Oh, IY | 1 |
Yoon, CH | 1 |
Suh, JW | 1 |
Choi, SI | 3 |
Youn, TJ | 1 |
Koo, BK | 1 |
Chae, IH | 1 |
Choi, DJ | 2 |
Leone, AM | 1 |
Scalone, G | 1 |
De Maria, GL | 1 |
Tagliaferro, F | 1 |
Gardi, A | 1 |
Clemente, F | 1 |
Basile, E | 1 |
Cialdella, P | 1 |
De Caterina, AR | 1 |
Porto, I | 1 |
Aurigemma, C | 1 |
Burzotta, F | 1 |
Niccoli, G | 1 |
Trani, C | 1 |
Rebuzzi, AG | 1 |
Crea, F | 1 |
den Dekker, MAM | 1 |
Pelgrim, GJ | 1 |
Pundziute, G | 1 |
van den Heuvel, ER | 1 |
Oudkerk, M | 1 |
Vliegenthart, R | 1 |
Ko, BS | 1 |
Wong, DT | 1 |
Nørgaard, BL | 1 |
Leong, DP | 1 |
Cameron, JD | 1 |
Gaur, S | 1 |
Marwan, M | 1 |
Achenbach, S | 2 |
Kuribayashi, S | 1 |
Kimura, T | 1 |
Meredith, IT | 1 |
Seneviratne, SK | 1 |
Paul, JF | 1 |
Laurent, F | 1 |
Becker, HC | 1 |
Rengo, M | 1 |
Caudron, J | 1 |
Leschka, S | 1 |
Vignaux, O | 1 |
Knobloch, G | 1 |
Benea, G | 1 |
Schlosser, T | 1 |
Andreu, J | 1 |
Cabeza, B | 1 |
Jacquier, A | 1 |
Souto, M | 1 |
Revel, D | 1 |
Qanadli, SD | 1 |
Cademartiri, F | 6 |
Wilhelmi, M | 1 |
Gasser, S | 1 |
Reimann, AJ | 2 |
Tsiflikas, I | 3 |
Brodoefel, H | 3 |
Scheuering, M | 1 |
Rinck, D | 1 |
Kopp, AF | 4 |
Claussen, CD | 4 |
Heuschmid, M | 4 |
Krug, KB | 1 |
Bovenschulte, H | 2 |
Geissler, HJ | 1 |
Flesch, M | 1 |
Schneider, T | 2 |
Brackrogge, D | 1 |
Reiter, H | 1 |
Heppelmann, I | 1 |
Christ, H | 1 |
Fischer, JH | 1 |
Lackner, KJ | 1 |
Steppich, BA | 1 |
Kaufmann, J | 1 |
Sepp, D | 1 |
Kunert, K | 1 |
Rutz, T | 1 |
Stratz, C | 1 |
Ott, I | 1 |
Romagnoli, A | 1 |
Martuscelli, E | 1 |
Sperandio, M | 1 |
Arganini, C | 1 |
De Angelis, B | 1 |
Acampora, V | 1 |
Patrei, A | 1 |
Bazzocchi, G | 1 |
Romeo, F | 1 |
Simonetti, G | 1 |
van Velzen, JE | 1 |
Schuijf, JD | 2 |
van Werkhoven, JM | 1 |
Herzog, BA | 1 |
Pazhenkottil, AP | 1 |
Boersma, E | 1 |
de Graaf, FR | 1 |
Scholte, AJ | 1 |
Kroft, LJ | 2 |
de Roos, A | 2 |
Stokkel, MP | 1 |
Jukema, JW | 1 |
Kaufmann, PA | 1 |
van der Wall, EE | 1 |
Bax, JJ | 2 |
Maffei, E | 4 |
Palumbo, A | 3 |
Martini, C | 2 |
Ugo, F | 2 |
Lina, D | 2 |
Aldrovandi, A | 4 |
Reverberi, C | 2 |
Manca, C | 1 |
Ardissino, D | 2 |
Crisi, G | 1 |
Hadamitzky, M | 1 |
Distler, R | 1 |
Meyer, T | 1 |
Hein, F | 1 |
Kastrati, A | 1 |
Martinoff, S | 1 |
Schömig, A | 1 |
Hausleiter, J | 1 |
van der Bijl, N | 1 |
Joemai, RM | 1 |
Geleijns, J | 1 |
Lim, S | 1 |
Shin, H | 1 |
Lee, Y | 1 |
Yoon, JW | 1 |
Kang, SM | 1 |
Choi, SH | 1 |
Park, KS | 1 |
Jang, HC | 1 |
Rossi, A | 1 |
Mollet, N | 2 |
Lario, C | 1 |
Castiglione Morelli, M | 1 |
Clemente, A | 1 |
Gentile, G | 1 |
Arcadi, T | 1 |
Seitun, S | 1 |
Catalano, O | 1 |
Yoo, DH | 1 |
Kim, JA | 1 |
Jin, KN | 1 |
Yeon, TJ | 1 |
Krug, B | 1 |
Schwabe, H | 1 |
Kabbasch, C | 1 |
Bangard, C | 1 |
Hellmich, M | 1 |
Michels, G | 1 |
Maintz, D | 1 |
Lackner, K | 1 |
Marano, R | 1 |
Luccichenti, G | 1 |
Runza, G | 2 |
Galia, M | 1 |
Belgrano, M | 1 |
Gualerzi, M | 1 |
Brambilla, L | 1 |
Coruzzi, P | 1 |
Midiri, M | 3 |
Andreini, D | 1 |
Pontone, G | 1 |
Pepi, M | 1 |
Ballerini, G | 1 |
Bartorelli, AL | 1 |
Magini, A | 1 |
Quaglia, C | 1 |
Nobili, E | 1 |
Agostoni, P | 1 |
Reimann, A | 2 |
Burgstahler, C | 3 |
Schumacher, F | 2 |
Herberts, T | 1 |
Schroeder, S | 2 |
Kuettner, A | 1 |
Klumpp, B | 1 |
Teufel, M | 1 |
Beck, T | 1 |
Schröder, S | 1 |
Malagò, R | 2 |
Alberghina, F | 1 |
Brambilla, V | 1 |
La Grutta, L | 1 |
Menozzi, A | 2 |
Vignali, L | 2 |
Casolo, G | 1 |
Mollet, NR | 2 |
Notarangelo, F | 1 |
Solinas, E | 1 |
Cervellin, G | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
HeartFlowNXT - HeartFlow Analysis of Coronary Blood Flow Using Coronary CT Angiography: NeXt sTeps[NCT01757678] | 276 participants (Actual) | Interventional | 2012-09-30 | Completed | |||
Artificial Intelligence for Preventing Heart Disease: Observational, Single Center, Prospective and Retrospective Study[NCT06029387] | 3,000 participants (Anticipated) | Observational | 2023-07-31 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
The primary statistical measure will be the area under the receiver operating characteristic curve (AUC of ROC) of a patient-based model to detect hemodynamically significant obstruction. ROC graphs the change in sensitivity as the cut-point for positive/negative diagnosis moves from its lower to upper limit. FFR is used as the reference standard to determine the presence or absence of hemodynamic obstruction. For FFR, hemodynamically-significant obstruction of a coronary artery is defined as an FFR≤0.80 in any major epicardial coronary artery segment with diameter ≥2.0 mm during adenosine-mediated hyperemia. For cCTA, hemodynamically-significant obstruction of a coronary artery is defined as a stenosis >50% . FFRCT will be calculated for each patient as the minimum FFRCT in any coronary artery segment . cCTA stenosis will be calculated for each patient as the highest cCTA stenosis category for any vessel all measurements will take place only in segments with diameter ≥2.0 mm. (NCT01757678)
Timeframe: 1 day; Outcome measures were comparing FFRct to FFR. Incident time for FFR was dependent on the length of time on the cath procedure. FFRct was done remotely at HeartFlow's processing center in Redwood City with a turnaround time of 24 hours from CT scan.
Intervention | probablility (Number) |
---|---|
FFRct vs. FFR | .90 |
cCTA vs. FFR | .81 |
(NCT01757678)
Timeframe: 1 day
Intervention | probability (Number) |
---|---|
FFRct vs. FFR | .93 |
cCTA vs. FFR | .79 |
(NCT01757678)
Timeframe: 1 day; Outcome measures were comparing FFRct to FFR. Incident time for FFR was dependent on the length of time on the cath procedure. FFRct was done remotely at HeartFlow's processing center in Redwood City with a turnaround time of 24 hours from CT scan.
Intervention | percentage of tests (Number) | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Accuracy: ICA Stenosis >50% | Accuracy: FFRct ≤ 0.80 | Accuracy: Coronary CTA Stenosis >50% | Sensitivity: ICA Stenosis >50% | Sensitivity: FFRct ≤ 0.80 | Sensitivity: Coronary CTA Stenosis >50% | Specificity: ICA Stenosis >50% | Specificity: FFRct ≤ 0.80 | Specificity: Coronary CTA Stenosis >50% | Positive Predictive Value: ICA Stenosis >50% | Positive Predictive Value: FFRct ≤ 0.80 | Positive Predictive Value: cCTA Stenosis >50% | Negative Predictive Value: ICA Stenosis >50% | Negative Predictive Value: FFRct ≤ 0.80 | Negative Predictive Value: cCTA Stenosis >50% | |
Standard of Care: FFR and ICA | 82 | 86 | 65 | 55 | 84 | 83 | 90 | 86 | 60 | 58 | 61 | 33 | 88 | 95 | 92 |
(NCT01757678)
Timeframe: 1 day; Outcome measures were comparing FFRct to FFR. Incident time for FFR was dependent on the length of time on the cath procedure. FFRct was done remotely at HeartFlow's processing center in Redwood City with a turnaround time of 24 hours from CT scan.
Intervention | percentage of tests (Number) | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Accuracy: ICA Stenosis >50% | Accuracy: FFRct ≤ 0.80 | Accuracy: Coronary CTA Stenosis >50% | Sensitivity: ICA Stenosis >50% | Sensitivity: FFRct ≤ 0.80 | Sensitivity: Coronary CTA Stenosis >50% | Specificity: ICA Stenosis >50% | Specificity: FFRct ≤ 0.80 | Specificity: Coronary CTA Stenosis >50% | Positive Predictive Value: ICA Stenosis >50% | Positive Predictive Value: FFRct ≤ 0.80 | Positive Predictive Value: cCTA Stenosis >50% | Negative Predictive Value: ICA Stenosis >50% | Negative Predictive Value: FFRct ≤ 0.80 | Negative Predictive Value: cCTA Stenosis >50% | |
Standard of Care: FFR and ICA | 77 | 81 | 53 | 64 | 86 | 94 | 83 | 79 | 34 | 63 | 65 | 40 | 83 | 93 | 92 |
(NCT01757678)
Timeframe: 1 day; Outcome measures were comparing FFRct to FFR. Incident time for FFR was dependent on the length of time on the cath procedure. FFRct was done remotely at HeartFlow's processing center in Redwood City with a turnaround time of 24 hours from CT scan.
Intervention | percentage of tests (Number) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Accuracy: FFRct ≤ 0.80 | Accuracy: Coronary CTA Stenosis > 50% | Sensitivity: FFRct ≤ 0.80 | Sensitivity: Coronary CTA Stenosis >50% | Specificity: FFRct ≤ 0.80 | Specificity: Coronary CTA Stenosis > 50% | Positive Predictive Value: FFRct ≤ 0.80 | Positive Predictive Value: cCTA Stenosis > 50% | Negative Predictive Value: FFRct ≤ 0.80 | Negative Predictive Value: cCTA Stenosis > 50% | |
Standard of Care: FFR and ICA | 80 | 51 | 85 | 93 | 79 | 32 | 63 | 37 | 92 | 91 |
3 trials available for iomeprol and Coronary Stenosis
Article | Year |
---|---|
Comparative assessment of image quality for coronary CT angiography with iobitridol and two contrast agents with higher iodine concentrations: iopromide and iomeprol. A multicentre randomized double-blind trial.
Topics: Adult; Aged; Calcinosis; Computed Tomography Angiography; Contrast Media; Coronary Angiography; Coro | 2017 |
Diagnostic accuracy of computed tomography coronary angiography in a high risk symptomatic population.
Topics: Aged; Cohort Studies; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Humans; Iopam | 2010 |
Diagnostic accuracy of multidetector computed tomography coronary angiography in patients with dilated cardiomyopathy.
Topics: Artifacts; Cardiomyopathy, Dilated; Contrast Media; Coronary Angiography; Coronary Artery Disease; C | 2007 |
26 other studies available for iomeprol and Coronary Stenosis
Article | Year |
---|---|
Strengths and limitations of coronary angiography with turbo high-pitch third-generation dual-source CT.
Topics: Aged; Cardiac-Gated Imaging Techniques; Computed Tomography Angiography; Contrast Media; Coronary An | 2017 |
Simplified hybrid algorithms for pressure wire interrogation exploiting advantages of a baseline and contrast Pd/Pa ratio indexes to predict stenosis significance: Insight from the SPARE multicenter prospective study.
Topics: Adenosine; Aged; Algorithms; Cardiac Catheterization; Cardiac Catheters; Clinical Decision-Making; C | 2018 |
Myocardium: dynamic versus single-shot CT perfusion imaging.
Topics: Aged; Comorbidity; Contrast Media; Coronary Angiography; Coronary Stenosis; Exercise Test; Female; F | 2013 |
Predictive value of zero calcium score and low-end percentiles for the presence of significant coronary artery stenosis in stable patients with suspected coronary artery disease.
Topics: Aged; Aged, 80 and over; Body Mass Index; Calcinosis; Cardiac Catheterization; Cardiac-Gated Imaging | 2013 |
Potential predictors of side-branch occlusion in bifurcation lesions after percutaneous coronary intervention: a coronary CT angiography study.
Topics: Cardiac-Gated Imaging Techniques; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; H | 2014 |
Efficacy of contrast medium induced Pd/Pa ratio in predicting functional significance of intermediate coronary artery stenosis assessed by fractional flow reserve: insights from the RINASCI study.
Topics: Adenosine; Aged; Area Under Curve; Cardiac Catheterization; Contrast Media; Coronary Angiography; Co | 2015 |
Hemodynamic significance of coronary stenosis by vessel attenuation measurement on CT compared with adenosine perfusion MRI.
Topics: Adenosine; Adult; Aged; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Hemodynamic | 2015 |
Diagnostic Performance of Transluminal Attenuation Gradient and Noninvasive Fractional Flow Reserve Derived from 320-Detector Row CT Angiography to Diagnose Hemodynamically Significant Coronary Stenosis: An NXT Substudy.
Topics: Blood Flow Velocity; Cardiac-Gated Imaging Techniques; Contrast Media; Coronary Angiography; Coronar | 2016 |
[Recurrent parotid enlargement following coronary angiography].
Topics: Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Coronary Stenosis; Diagnosis, | 2008 |
Efficacy of computer aided analysis in detection of significant coronary artery stenosis in cardiac using dual source computed tomography.
Topics: Aged; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Humans; Imaging, Three-Dimens | 2009 |
In-vivo measurements of coronary blood flow using 16-slice multidetector spiral computed tomography (MDCT) in a porcine model.
Topics: Animals; Blood Flow Velocity; Blood Volume; Contrast Media; Coronary Angiography; Coronary Circulati | 2009 |
Increased circulating placental growth factor during percutaneous coronary intervention is associated with applied radiocontrast agent.
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Anticoagulants; Biomarkers; Case-Control Studies; C | 2009 |
Role of 64-slice cardiac computed tomography in the evaluation of patients with non-ST-elevation acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Analysis of Variance; Chi-Square Distribution; Contrast Media; Corona | 2010 |
Predictive value of multislice computed tomography variables of atherosclerosis for ischemia on stress-rest single-photon emission computed tomography.
Topics: Atherosclerosis; Contrast Media; Coronary Angiography; Coronary Stenosis; Coronary Vessels; Exercise | 2010 |
Prognostic value of coronary computed tomographic angiography in comparison with calcium scoring and clinical risk scores.
Topics: Aged; Calcinosis; Contrast Media; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; | 2011 |
Assessment of Agatston coronary artery calcium score using contrast-enhanced CT coronary angiography.
Topics: Calcinosis; Contrast Media; Coronary Angiography; Coronary Stenosis; Electrocardiography; Female; Hu | 2010 |
Effect of metabolic syndrome on coronary artery stenosis and plaque characteristics as assessed with 64-detector row cardiac CT.
Topics: Adult; Aged; Anthropometry; Calcinosis; Chi-Square Distribution; Contrast Media; Coronary Artery Dis | 2011 |
Diagnostic accuracy of second-generation dual-source computed tomography coronary angiography with iterative reconstructions: a real-world experience.
Topics: Algorithms; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Humans; Iopamidol; Like | 2012 |
Significance of noncalcified coronary plaque in asymptomatic subjects with low coronary artery calcium score: assessment with coronary computed tomography angiography.
Topics: Calcinosis; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Follow-Up Studies; Huma | 2011 |
CT coronary angiography: coronary CT-flow quantification supplements morphological stenosis analysis.
Topics: Aged; Blood Flow Velocity; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Humans; | 2013 |
Image assessment with multislice CT coronary angiography.
Topics: Contrast Media; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Female; Humans; Im | 2005 |
Noninvasive coronary angiography using 64-slice spiral computed tomography in an unselected patient collective: effect of heart rate, heart rate variability and coronary calcifications on image quality and diagnostic accuracy.
Topics: Body Mass Index; Calcinosis; Chi-Square Distribution; Contrast Media; Coronary Angiography; Coronary | 2008 |
Late enhancement using multidetector row computer tomography: a feasibility study with low dose 80 kV protocol.
Topics: Adult; Aged; Contrast Media; Coronary Angiography; Coronary Stenosis; Feasibility Studies; Female; G | 2008 |
Diagnostic accuracy of 64-slice computed tomography coronary angiography in patients with low-to-intermediate risk.
Topics: Algorithms; Chest Pain; Contrast Media; Coronary Angiography; Coronary Disease; Coronary Stenosis; D | 2007 |
Dual-source CT: effect of heart rate, heart rate variability, and calcification on image quality and diagnostic accuracy.
Topics: Algorithms; Calcinosis; Contrast Media; Coronary Angiography; Coronary Stenosis; Female; Heart Rate; | 2008 |
64-slice computed tomography coronary angiography: diagnostic accuracy in the real world.
Topics: Aged; Contrast Media; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Female; Huma | 2008 |