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iohexol and Ventricular Fibrillation

iohexol has been researched along with Ventricular Fibrillation in 24 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.

Research Excerpts

ExcerptRelevanceReference
"We investigated whether addition of a balanced electrolyte supplement and oxygen to the nonionic contrast medium iohexol reduces the risk of ventricular fibrillation (VF), and studied regional electrophysiology prior to the VF event."7.69Cardiac effects of adding electrolytes and oxygen to iohexol in a dog model of contrast media-induced ventricular fibrillation. ( Jacobsen, EA; Kløw, NE; Pedersen, HK; Refsum, H, 1995)
"The influence on contractile force (CF) and the propensity for ventricular fibrillation (VF) from infusing the non-ionic contrast medium iohexol during normal (75 cm H2O) and reduced perfusion pressure (35 cm H2O) were investigated in the isolated rabbit heart."7.68Sodium addition and/or oxygen saturation of iohexol during normal and reduced perfusion pressure. Effects on contractile force and risk of ventricular fibrillation in the isolated rabbit heart. ( Bååth, L, 1990)
"The incidence of major ECG changes, particularly ventricular fibrillation, was evaluated in rabbits during prolonged, selective right coronary injection of sodium/meglumine ioxaglate (Hexabrix 160) and iohexol (Omnipaque 140), two isotonic contrast media."7.67Incidence of ventricular fibrillation during coronary arteriography in the rabbit. A comparative study of isotonic ioxaglate and iohexol. ( Bonnemain, B; Cardinal, A; Donadieu, AM; Hartl, C, 1987)
"Ioxilan has the least arrythmogenic property among the current low-osmolality nonionic CMs."5.31The risk of contrast media-induced ventricular fibrillation is low in canine coronary arteriography with ioxilan. ( Fujiki, M; Misumi, K; Miura, N; Sakamoto, H; Tateno, O, 2000)
"The effect of addition of calcium, potassium and magnesium to iohexol (350 mg I/ml) enriched with 30 mM sodium was investigated with regard to ventricular fibrillation (VF) in isolated rabbit hearts."3.68Reduced risk of ventricular fibrillation by balancing sodium, calcium, potassium and magnesium added to nonionic contrast media. An investigation in the isolated rabbit heart. ( Almén, T; Bååth, L; Besjakov, J; Oksendal, AN, 1993)
"Ioxilan has the least arrythmogenic property among the current low-osmolality nonionic CMs."1.31The risk of contrast media-induced ventricular fibrillation is low in canine coronary arteriography with ioxilan. ( Fujiki, M; Misumi, K; Miura, N; Sakamoto, H; Tateno, O, 2000)
"Ventricular fibrillation was difficult to induce with standard solutions of these agents (even with three extra stimuli), but became progressively easier to induce when NaCl was added."1.27The effect of sodium on the fibrillatory propensity of nonionic contrast media. ( Hwang, MH; Murdock, DK; Piao, ZE; Raymond, RM; Scanlon, PJ, 1987)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19907 (29.17)18.7374
1990's12 (50.00)18.2507
2000's5 (20.83)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pinès, E1
Zamia, P1
Idée, JM2
Gayet, JL1
Lefevre, T2
Kao, HW1
Wu, CJ1
Lo, CP1
Chang, WC1
Chen, CY1
Chai, CM2
Karlsson, JO1
Almén, T6
Jacobsen, EA3
Pedersen, HK3
Kløw, NE2
Refsum, H3
Besjakov, J3
Bååth, L7
Oksendal, A3
Oksendal, AN1
Matalon, C1
Koeltz, B1
Bonnemain, B2
Mortensen, E1
Misumi, K1
Tateno, O1
Fujiki, M1
Miura, N1
Sakamoto, H1
Carey, D1
Hurst, JW1
Silverman, ME1
Pinto, IM1
Kou, WH1
McGillem, MJ1
DeBoe, SF1
Mickelson, JK1
Mancini, GB1
Morris, TW2
Piao, ZE2
Murdock, DK2
Hwang, MH2
Raymond, RM2
Scanlon, PJ2
Hayakawa, K1
Sahler, LG1
Ekholm, S1
Donadieu, AM1
Hartl, C1
Cardinal, A1

Other Studies

24 other studies available for iohexol and Ventricular Fibrillation

ArticleYear
In response to: K. Vijayalakshmi, et al, vol. 16, no. 12, pp. 707-711: A prospective, randomized trial to determine the early and late reactions after the use of iopamidol 340 (Niopam) and iobitridol 350 (Xenetix) in cardiac catheterization.
    The Journal of invasive cardiology, 2005, Volume: 17, Issue:2

    Topics: Cardiac Catheterization; Contrast Media; Double-Blind Method; Electrocardiography; Humans; Incidence

2005
In response to: K. Vijayalakshmi, et al, vol. 16, no. 12, pp. 707-711: A prospective, randomized trial to determine the early and late reactions after the use of iopamidol 340 (Niopam) and iobitridol 350 (Xenetix) in cardiac catheterization.
    The Journal of invasive cardiology, 2005, Volume: 17, Issue:2

    Topics: Cardiac Catheterization; Contrast Media; Double-Blind Method; Electrocardiography; Humans; Incidence

2005
Computed tomographic features of circulatory arrest.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2006, Volume: 105, Issue:4

    Topics: Adult; Aged; Contrast Media; Fatal Outcome; Heart Arrest; Humans; Iohexol; Male; Tomography, X-Ray C

2006
Incidence of ventricular fibrillation during left coronary arteriography in pigs: comparison of a solution of the nonionic dimer iodixanol with solutions of five different nonionic monomers.
    Acta radiologica (Stockholm, Sweden : 1987), 2008, Volume: 49, Issue:2

    Topics: Animals; Catheterization; Contrast Media; Coronary Angiography; Coronary Vessels; Electrolytes; Fema

2008
Cardiac effects of adding electrolytes and oxygen to iohexol in a dog model of contrast media-induced ventricular fibrillation.
    Acta radiologica (Stockholm, Sweden : 1987), 1995, Volume: 36, Issue:1

    Topics: Action Potentials; Animals; Dogs; Electrocardiography; Electrolytes; Female; Heart; Iohexol; Male; O

1995
Comparison between oxygenated iohexol solution enriched with electrolytes and other low-osmotic contrast media. Electrophysiologic and hemodynamic effects during perfusion of the left coronary artery in the pig.
    Investigative radiology, 1994, Volume: 29 Suppl 2

    Topics: Animals; Contrast Media; Coronary Vessels; Electrocardiography; Electrolytes; Heart; Injections, Int

1994
Sodium-calcium balance in nonionic contrast media. Effects on the risk of ventricular fibrillation in the isolated rabbit heart.
    Investigative radiology, 1993, Volume: 28, Issue:3

    Topics: Animals; Calcium; Contrast Media; Coronary Angiography; In Vitro Techniques; Iohexol; Rabbits; Risk

1993
Reduced risk of ventricular fibrillation by balancing sodium, calcium, potassium and magnesium added to nonionic contrast media. An investigation in the isolated rabbit heart.
    Acta radiologica (Stockholm, Sweden : 1987), 1993, Volume: 34, Issue:3

    Topics: Animals; Calcium; Electrolytes; Female; Heart; In Vitro Techniques; Iohexol; Magnesium; Male; Potass

1993
Electrolyte addition to nonionic contrast media. Cardiac effects during experimental coronary arteriography.
    Acta radiologica. Supplementum, 1996, Volume: 405

    Topics: Animals; Anti-Arrhythmia Agents; Contrast Media; Coronary Angiography; Dogs; Electrolytes; Heart; He

1996
Contrast-medium-induced ventricular fibrillation: arrhythmogenic mechanisms and the role of antiarrhythmic drugs in dogs.
    Academic radiology, 1996, Volume: 3, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Contrast Media; Dogs; Electrocardiography; Iohexol; Ioxaglic Acid;

1996
Role of sodium addition to nonionic contrast medium in preventing ventricular fibrillation during coronary arteriography in dogs.
    Academic radiology, 1994, Volume: 1, Issue:3

    Topics: Action Potentials; Analysis of Variance; Animals; Chi-Square Distribution; Contrast Media; Coronary

1994
Contrast-medium-induced ventricular fibrillation: arrhythmogenic mechanisms and the role of antiarrhythmic drugs in dogs.
    Academic radiology, 1995, Volume: 2, Issue:12

    Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Catheterization; Contrast Media; Cor

1995
The risk of contrast media-induced ventricular fibrillation is low in canine coronary arteriography with ioxilan.
    The Journal of veterinary medical science, 2000, Volume: 62, Issue:4

    Topics: Animals; Contrast Media; Coronary Angiography; Dog Diseases; Dogs; Female; Iohexol; Iopamidol; Male;

2000
Coronary spasm and cardiac arrest after coronary arteriography in unsuspected thyrotoxicosis.
    The American journal of cardiology, 1992, Sep-15, Volume: 70, Issue:7

    Topics: Coronary Angiography; Coronary Vasospasm; Female; Heart Arrest; Humans; Iohexol; Middle Aged; Thyrot

1992
Oxygen saturation of the low osmolar contrast media iohexol, ioxaglate and iodixanol. Effects on contractile force and frequency of ventricular fibrillation in the isolated rabbit heart.
    Acta radiologica (Stockholm, Sweden : 1987), 1990, Volume: 31, Issue:5

    Topics: Animals; Female; Heart; Hypoxia; Iohexol; Ioxaglic Acid; Male; Myocardial Contraction; Myocardium; O

1990
Sodium addition and/or oxygen saturation of iohexol during normal and reduced perfusion pressure. Effects on contractile force and risk of ventricular fibrillation in the isolated rabbit heart.
    Acta radiologica (Stockholm, Sweden : 1987), 1990, Volume: 31, Issue:5

    Topics: Animals; Blood Pressure; Contrast Media; Female; Heart; Iohexol; Male; Myocardial Contraction; Oxyge

1990
Cardiac effects from addition of sodium ions to nonionic contrast media for coronary arteriography. An investigation of the isolated rabbit heart.
    Investigative radiology, 1990, Volume: 25 Suppl 1

    Topics: Animals; Contrast Media; Coronary Angiography; In Vitro Techniques; Iohexol; Ions; Myocardial Contra

1990
Induction of ventricular arrhythmia by high and low osmolarity ionic and nonionic contrast media.
    American heart journal, 1989, Volume: 117, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Diatrizoate; Dogs; Electrocardiography;

1989
Selective injection of iopentol, iohexol and metrizoate into the left coronary artery of the dog. Induction of ventricular fibrillation and decrease of aortic pressure.
    Acta radiologica. Supplementum, 1987, Volume: 370

    Topics: Animals; Aorta; Blood Pressure; Contrast Media; Coronary Angiography; Dogs; Electrocardiography; Fem

1987
Ventricular fibrillation during right coronary arteriography with ioxaglate, iohexol and iopamidol in dogs.
    Investigative radiology, 1988, Volume: 23, Issue:3

    Topics: Animals; Coronary Angiography; Dogs; Female; Iohexol; Iopamidol; Ioxaglic Acid; Male; Ventricular Fi

1988
Contrast media-induced ventricular fibrillation. A comparison of Hypaque-76, Hexabrix, and Omnipaque.
    Investigative radiology, 1988, Volume: 23, Issue:6

    Topics: Angiography; Animals; Contrast Media; Coronary Angiography; Diatrizoate; Diatrizoate Meglumine; Dogs

1988
The effect of sodium on the fibrillatory propensity of nonionic contrast media.
    Investigative radiology, 1987, Volume: 22, Issue:11

    Topics: Animals; Contrast Media; Coronary Angiography; Dogs; Drug Antagonism; Drug Synergism; Female; Humans

1987
Incidence of fibrillation with isotonic contrast media for intra-arterial coronary digital subtraction angiography.
    Diagnostic imaging in clinical medicine, 1986, Volume: 55, Issue:3

    Topics: Angiography; Animals; Contrast Media; Coronary Angiography; Diatrizoate; Diatrizoate Meglumine; Dogs

1986
Incidence of ventricular fibrillation during coronary arteriography in the rabbit. A comparative study of isotonic ioxaglate and iohexol.
    Investigative radiology, 1987, Volume: 22, Issue:2

    Topics: Animals; Blood Pressure; Coronary Angiography; Electrocardiography; Heart Rate; Injections, Intra-Ar

1987