Page last updated: 2024-10-29

iohexol and Thrombosis

iohexol has been researched along with Thrombosis in 38 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.

Research Excerpts

ExcerptRelevanceReference
" The nonionic CM iohexol triggers platelet beta-thromboglobulin (beta-TG) secretion, and thus may activate the platelets and promote thrombosis."7.70Iohexol, platelet activation and thrombosis. II. Iohexol-induced platelet secretion does not affect collagen-induced or tissue-factor-induced thrombus formation in blood that is anticoagulated with heparin and aspirin. ( Buchmann, M; Hamers, MJ; Sakariassen, KS; Stormorken, H, 1998)
"Ioxaglate and iodixanol were virtually inert."5.30Iohexol, platelet activation and thrombosis. I. Iohexol-induced platelet secretion does not affect thrombus formation in native blood. ( Barstad, RM; Hamers, MJ; Sakariassen, KS; Stormorken, H, 1998)
"Low-osmolar ionic (ioxaglate) or nonionic (iohexol) contrast material was administered to 14 patients undergoing pulmonary angiography for suspected pulmonary embolism."5.07Increased plasma levels of PAI-1 after administration of nonionic contrast medium in patients undergoing pulmonary angiography. ( Büller, HR; Hack, CE; Levi, M; Reekers, JA; ten Cate, JW; Van Beek, EJ, 1994)
"Comparing iohexol 240 mg I/ml, iohexol 300 mg I/ml and meglumine-Ca metrizoate 200 mg I/ml in phlebography of the leg in patients on or without anticoagulants, no sign of post-phlebographic thrombosis was found using the 125I-fibrinogen uptake test and repeat phlebography."5.05Iohexol in phlebography of the leg. A comparative investigation with meglumine metrizoate. ( Andrew, E; Enge, I; Gjølberg, T, 1983)
" The nonionic CM iohexol triggers platelet beta-thromboglobulin (beta-TG) secretion, and thus may activate the platelets and promote thrombosis."3.70Iohexol, platelet activation and thrombosis. II. Iohexol-induced platelet secretion does not affect collagen-induced or tissue-factor-induced thrombus formation in blood that is anticoagulated with heparin and aspirin. ( Buchmann, M; Hamers, MJ; Sakariassen, KS; Stormorken, H, 1998)
"Endoleaks, intraluminal thrombus and limb stenoses, contrast agent use, and radiation exposure were recorded for all modalities."1.43Intraoperative contrast-enhanced cone beam computed tomography to assess technical success during endovascular aneurysm repair. ( Böckler, D; Geisbüsch, P; Schmitt, M; Schulz, CJ, 2016)
"False lumen thrombosis after aortic dissection is a major predictor of prognosis."1.37A new method for quantification of false lumen thrombosis in aortic dissection using magnetic resonance imaging and a blood pool contrast agent. ( Clough, RE; Greil, GF; Hussain, T; Razavi, R; Schaeffter, T; Taylor, PR; Uribe, S; Waltham, M, 2011)
"Thrombosis was measured over a blood exposure period of 2 hours by gamma camera imaging of 111In-platelets and by gamma counting of deposited 125I-fibrin."1.31Antithrombotic effects of ionic and non-ionic contrast media in nonhuman primates. ( Chronos, NA; Hanson, SR; Markou, CP, 2001)
"Helical CT scans depicted thrombus in nine (90%) of 10 patients (95% confidence interval = 0."1.30Portal venous system thrombosis: helical CT angiography before transjugular intrahepatic portosystemic shunt creation. ( Fishman, EK; Heath, DG; Kuszyk, BS; Osterman, FA; Smith, PA; Urban, BA; Venbrux, AC, 1998)
"Ioxaglate and iodixanol were virtually inert."1.30Iohexol, platelet activation and thrombosis. I. Iohexol-induced platelet secretion does not affect thrombus formation in native blood. ( Barstad, RM; Hamers, MJ; Sakariassen, KS; Stormorken, H, 1998)
"Recurrent pulmonary embolism was not suspected in any of these patients, and five autopsies revealed no caval thrombosis."1.29Follow-up after insertion of Bird's Nest inferior vena caval filters. ( Common, AA; Starok, MS, 1996)
"Ioxaglate significantly inhibited thrombus growth (60% inhibition, P less than 0."1.28Effect on thrombus growth and thrombolysis of two types of osmolar contrast media in rabbits. ( Agnelli, G; Hoek, J; Levi, M; Pascucci, C; Sturk, A; Wouter ten Cate, J, 1990)
"Coronary thrombus or embolus occurred in 7 patients, a thromboembolus from the ventricular catheter occurred in 1 patients and transient ischemic attack or stroke occurred in 7 patients."1.28Thrombotic and cardiovascular complications related to nonionic contrast media during cardiac catheterization: analysis of 8,517 patients. ( Bashore, TM; Davidson, CJ; Gabriel, DA; Hlatky, MA; Kisslo, KB; Mark, DB; Pieper, KS, 1990)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.26)18.7374
1990's19 (50.00)18.2507
2000's9 (23.68)29.6817
2010's8 (21.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gellada, NH1
Mieses, D1
Pimentel, R1
Yeo, LLL1
Holmin, S1
Andersson, T1
Lundström, E1
Gopinathan, A1
Lim, EL1
Leong, BSH1
Kuan, WS1
Ting, E1
Tan, BYQ1
Eide, SE1
Tay, ELK1
Zhang, LM1
Zhang, GY1
Liu, YL1
Wu, J1
Cheng, J1
Wang, Y1
Schulz, CJ1
Schmitt, M1
Böckler, D1
Geisbüsch, P1
Sueyoshi, E1
Onizuka, H1
Nagayama, H1
Sakamoto, I1
Uetani, M1
Park, EA1
Lee, W1
Chung, SY1
Yin, YH1
Chung, JW1
Park, JH1
Wang, YL1
Ding, PX1
Li, YD1
Han, XW1
Wu, G1
Clough, RE1
Hussain, T1
Uribe, S1
Greil, GF1
Razavi, R1
Taylor, PR1
Schaeffter, T1
Waltham, M1
Esplugas, E2
Cequier, A2
Gomez-Hospital, JA1
Del Blanco, BG1
Jara, F2
Lin, J1
Zhou, KR1
Chen, ZW1
Wang, JH1
Yan, ZP1
Wang, YX1
Jones, CI1
Goodall, AH1
Ruhl, KM1
Koos, R1
Mahnken, AH1
Servaes, S1
El-Haddad, G1
Zhuang, H1
Gjølberg, T1
Andrew, E1
Enge, I1
Abeyama, K1
Oh, S1
Kawano, K1
Nakajima, T1
Soejima, Y1
Nakano, K1
Maruyama, I1
Corot, C2
Stucker, O1
Duverger, JP1
Pons, C1
Vicaut, E1
Van Beek, EJ1
Levi, M2
Reekers, JA1
Hack, CE1
Büller, HR1
ten Cate, JW1
Mauri, J1
Soler, T1
Sala, J1
Sabate, X1
Starok, MS1
Common, AA1
Orme, RI1
Guest, PJ1
Sato, E1
Saito, I1
Barstad, RM2
Buchmann, MS1
Hamers, MJ3
Orning, L1
Orvim, U1
Stormorken, H3
Sakariassen, KS3
Hardee, MS1
Bashore, TM2
Kuszyk, BS1
Osterman, FA1
Venbrux, AC1
Heath, DG1
Urban, BA1
Smith, PA1
Fishman, EK1
Buchmann, M1
Chronos, N1
Blanco, J1
Aguejouf, O1
Malfatti, E1
Doutremepuich, F1
Doutremepuich, C1
Markou, CP1
Chronos, NA1
Hanson, SR1
Ogawa, T1
Fujii, S1
Urasawa, K1
Kitabatake, A1
Zhu, Y1
Tomasiak, R1
Fay, WP1
Hentschel, F1
Rieber, A1
Claussen, CD1
Cornillac, A1
Belleville, J1
Eloy, R1
Mamon, JF1
Fareed, J1
Hoppensteadt, D1
Moncada, R1
Hwang, MH1
Piao, ZE1
Murdock, DK1
Messmore, HL1
Giardina, JJ1
Scanlon, PJ1
Pascucci, C1
Agnelli, G1
Sturk, A1
Hoek, J1
Wouter ten Cate, J1
Davidson, CJ1
Mark, DB1
Pieper, KS1
Kisslo, KB1
Hlatky, MA1
Gabriel, DA1
Hoogewoud, HM1
Petropoulos, P1

Reviews

1 review available for iohexol and Thrombosis

ArticleYear
Comparative tolerability of contrast media used for coronary interventions.
    Drug safety, 2002, Volume: 25, Issue:15

    Topics: Cardiovascular Diseases; Cardiovascular Surgical Procedures; Cardiovascular System; Clinical Trials

2002

Trials

5 trials available for iohexol and Thrombosis

ArticleYear
Comparative study of predilation with stent filter for Budd-Chiari syndrome with old IVC thrombosis: a nonrandomized prospective trial.
    European journal of radiology, 2012, Volume: 81, Issue:6

    Topics: Adult; Aged; Angiography; Budd-Chiari Syndrome; Catheterization; Contrast Media; Female; Fluoroscopy

2012
Iohexol in phlebography of the leg. A comparative investigation with meglumine metrizoate.
    Acta radiologica. Supplementum, 1983, Volume: 366

    Topics: Adult; Aged; Anticoagulants; Clinical Trials as Topic; Contrast Media; Drug Tolerance; Female; Human

1983
Increased plasma levels of PAI-1 after administration of nonionic contrast medium in patients undergoing pulmonary angiography.
    Radiology, 1994, Volume: 193, Issue:3

    Topics: Antithrombin III; Contrast Media; Female; Humans; Iohexol; Ioxaglic Acid; Male; Middle Aged; Osmolar

1994
Contrast media influence on thrombotic risk during coronary angioplasty.
    Seminars in thrombosis and hemostasis, 1993, Volume: 19 Suppl 1

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Double-Blind Method; Drug Costs; Female

1993
Risk of clot formation with ionic and nonionic contrast media in cerebral angiography. Tama Contrast Media Study Group.
    Academic radiology, 1996, Volume: 3, Issue:11

    Topics: Blood Coagulation; Cerebral Angiography; Contrast Media; Female; Humans; Iohexol; Iopamidol; Ioxagli

1996

Other Studies

32 other studies available for iohexol and Thrombosis

ArticleYear
Computed Tomography 4-D Valve Leaflet Assessment.
    Radiologic technology, 2019, Volume: 91, Issue:1

    Topics: Computed Tomography Angiography; Contrast Media; Echocardiography; Four-Dimensional Computed Tomogra

2019
Nongated Cardiac Computed Tomographic Angiograms for Detection of Embolic Sources in Acute Ischemic Stroke.
    Stroke, 2017, Volume: 48, Issue:5

    Topics: Aged; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Atrial Appendage; Brain Ischemia; Compute

2017
Ultrasonography and computed tomography diagnostic evaluation of Budd-Chiari syndrome based on radical resection exploration results.
    Ultrasound quarterly, 2015, Volume: 31, Issue:2

    Topics: Adult; Budd-Chiari Syndrome; Contrast Media; Female; Hepatic Veins; Humans; Iohexol; Liver; Male; Ra

2015
Intraoperative contrast-enhanced cone beam computed tomography to assess technical success during endovascular aneurysm repair.
    Journal of vascular surgery, 2016, Volume: 64, Issue:3

    Topics: Angiography, Digital Subtraction; Aortic Aneurysm, Abdominal; Aortography; Blood Vessel Prosthesis I

2016
Clinical importance of minimal enhancement of type B intramural hematoma of the aorta on computed tomography imaging.
    Journal of vascular surgery, 2017, Volume: 65, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aortic Aneurysm; Aortic Dissection; Aortography; Chi-Square Distribu

2017
Optimal scan timing and intravenous route for contrast-enhanced computed tomography in patients after Fontan operation.
    Journal of computer assisted tomography, 2010, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Artifacts; Child; Child, Preschool; Contrast Media; Female; Fontan Procedure; Hum

2010
A new method for quantification of false lumen thrombosis in aortic dissection using magnetic resonance imaging and a blood pool contrast agent.
    Journal of vascular surgery, 2011, Volume: 54, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aortic Aneurysm; Aortic Dissection; Aortography; Chronic Disease; Co

2011
3D contrast-enhanced MR portography and direct X-ray portography: a correlation study.
    European radiology, 2003, Volume: 13, Issue:6

    Topics: Adult; Carcinoma, Hepatocellular; Contrast Media; Female; Gadolinium DTPA; Humans; Hypertension, Por

2003
Differential effects of the iodinated contrast agents Ioxaglate, Iohexol and Iodixanol on thrombus formation and fibrinolysis.
    Thrombosis research, 2003, Volume: 112, Issue:1-2

    Topics: Blood Platelets; Contrast Media; Dose-Response Relationship, Drug; Fibrinolysis; Humans; Iohexol; Io

2003
Echocardiogram-gated multislice spiral CT in functionally univentricular heart following long-lasting Waterston-Cooley anastomosis.
    Australasian radiology, 2006, Volume: 50, Issue:5

    Topics: Adult; Anastomosis, Surgical; Anticoagulants; Contrast Media; Electrocardiography; Female; Heart; He

2006
Intense octreotide activity in a thrombus.
    Clinical nuclear medicine, 2008, Volume: 33, Issue:2

    Topics: Adult; Contrast Media; Female; Humans; Iohexol; Mediastinal Diseases; Octreotide; Radionuclide Imagi

2008
Nonionic contrast agents produce thrombotic effect by inducing adhesion of leukocytes on human endothelium.
    Biochemical and biophysical research communications, 1995, Jul-26, Volume: 212, Issue:3

    Topics: Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Contrast Media; Diatrizoate; E-Selectin; En

1995
Effects of iodinated contrast agents on the formation of platelet thrombi in rat arterioles.
    Investigative radiology, 1994, Volume: 29 Suppl 2

    Topics: Animals; Arterioles; Contrast Media; Iohexol; Ioxaglic Acid; Mesenteric Arteries; Microscopy, Video;

1994
Follow-up after insertion of Bird's Nest inferior vena caval filters.
    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 1996, Volume: 47, Issue:3

    Topics: Cause of Death; Contrast Media; Cost-Benefit Analysis; Critical Care; Equipment Design; Equipment Fa

1996
Resident's corner. Answer to case of the month #43. Mesenteric venous thrombosis with small-bowel infarction.
    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 1996, Volume: 47, Issue:6

    Topics: Adult; Contrast Media; Female; Humans; Infarction; Intestine, Small; Iohexol; Mesenteric Vascular Oc

1996
Effects of ionic and nonionic contrast media on endothelium and on arterial thrombus formation.
    Acta radiologica (Stockholm, Sweden : 1987), 1996, Volume: 37, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Cells, Cultured; Contrast Media; Endothelium, Vascular; Female; Huma

1996
Dealing with the highs and lows of contrast agents in left main disease.
    Catheterization and cardiovascular diagnosis, 1997, Volume: 42, Issue:4

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Contrast Media; Coronary Angiography; Coronary Disease; Diatr

1997
Portal venous system thrombosis: helical CT angiography before transjugular intrahepatic portosystemic shunt creation.
    Radiology, 1998, Volume: 206, Issue:1

    Topics: Contraindications; Contrast Media; Female; Humans; Image Processing, Computer-Assisted; Iohexol; Mal

1998
Iohexol, platelet activation and thrombosis. I. Iohexol-induced platelet secretion does not affect thrombus formation in native blood.
    Acta radiologica (Stockholm, Sweden : 1987), 1998, Volume: 39, Issue:4

    Topics: beta-Thromboglobulin; Blood Donors; Blood Platelets; Collagen; Contrast Media; Dose-Response Relatio

1998
Iohexol, platelet activation and thrombosis. II. Iohexol-induced platelet secretion does not affect collagen-induced or tissue-factor-induced thrombus formation in blood that is anticoagulated with heparin and aspirin.
    Acta radiologica (Stockholm, Sweden : 1987), 1998, Volume: 39, Issue:4

    Topics: Anticoagulants; Aspirin; beta-Thromboglobulin; Blood Platelets; Collagen; Contrast Media; Drug Inter

1998
Thrombogenic potential of non-ionic contrast media--fact or fiction? By Rainer Schrader.
    European journal of radiology, 1998, Volume: 28, Issue:1

    Topics: Contrast Media; Humans; Iohexol; Ioxaglic Acid; Risk Factors; Thrombosis

1998
Thrombogenic potential of contrast media in an experimental model of laser-induced thrombosis.
    Thrombosis research, 2000, Nov-01, Volume: 100, Issue:3

    Topics: Animals; Contrast Media; Diatrizoate; Disease Models, Animal; Dose-Response Relationship, Drug; Iohe

2000
Antithrombotic effects of ionic and non-ionic contrast media in nonhuman primates.
    Thrombosis and haemostasis, 2001, Volume: 85, Issue:3

    Topics: Animals; Arteriovenous Shunt, Surgical; Blood Flow Velocity; Contrast Media; Disease Models, Animal;

2001
Effects of nonionic contrast media on platelet aggregation: assessment by particle counting with laser-light scattering.
    Japanese heart journal, 2001, Volume: 42, Issue:1

    Topics: Angiography; Contrast Media; Female; Flow Cytometry; Humans; Iohexol; Iopamidol; Male; Osmolar Conce

2001
Do clinically relevant circulating concentrations of radiographic contrast agents inhibit platelet-dependent arterial thrombosis?
    Thrombosis research, 2002, Mar-01, Volume: 105, Issue:5

    Topics: Animals; Arterial Occlusive Diseases; Blood Circulation; Blood Coagulation; Blood Flow Velocity; Car

2002
[Pseudothrombosis of the vena cava superior and other flow artifacts in high-resolution rapid computed tomography of the thorax].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1992, Volume: 157, Issue:5

    Topics: Artifacts; Contrast Media; Diagnosis, Differential; Diagnostic Errors; Humans; Iohexol; Middle Aged;

1992
Scanning electron microscopic analysis of catheters during routine angiographic procedures. Role of the contrast agent. The European Clotting Group.
    Investigative radiology, 1991, Volume: 26 Suppl 1

    Topics: Angiocardiography; Angiography; Blood; Catheterization, Peripheral; Drug Interactions; Humans; Iohex

1991
Lack of inhibition of thrombin generation by nonionic contrast media.
    Thrombosis research, 1991, Jan-15, Volume: 61, Issue:2

    Topics: Antithrombin III; Contrast Media; Diatrizoate; Humans; In Vitro Techniques; Iohexol; Ioxaglic Acid;

1991
Risk of thromboembolism during diagnostic and interventional cardiac procedures with nonionic contrast media.
    Radiology, 1990, Volume: 174, Issue:2

    Topics: Animals; Cardiac Catheterization; Contrast Media; Coronary Angiography; Diatrizoate; Dogs; Female; H

1990
Effect on thrombus growth and thrombolysis of two types of osmolar contrast media in rabbits.
    Investigative radiology, 1990, Volume: 25, Issue:5

    Topics: Animals; Contrast Media; Iohexol; Ioxaglic Acid; Osmolar Concentration; Rabbits; Stimulation, Chemic

1990
Thrombotic and cardiovascular complications related to nonionic contrast media during cardiac catheterization: analysis of 8,517 patients.
    The American journal of cardiology, 1990, Jun-15, Volume: 65, Issue:22

    Topics: Aged; Cardiac Catheterization; Cardiovascular Diseases; Cerebrovascular Disorders; Embolism; Female;

1990
Renal embolization: a study of the interaction of contrast media and ethanol.
    Cardiovascular and interventional radiology, 1987, Volume: 10, Issue:4

    Topics: Aged; Drug Interactions; Embolization, Therapeutic; Ethanol; Humans; Iohexol; Iopamidol; Ioxaglic Ac

1987