iohexol has been researched along with Sciatica in 6 studies
Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.
Sciatica: A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of SCIATIC NEUROPATHY; RADICULOPATHY (involving the SPINAL NERVE ROOTS; L4, L5, S1, or S2, often associated with INTERVERTEBRAL DISK DISPLACEMENT); or lesions of the CAUDA EQUINA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grönneröd, TA | 1 |
| Eldevik, OP | 1 |
| Hindmarsh, T | 1 |
| Kendall, B | 1 |
| Nakstad, PH | 1 |
| Nakstad, P | 1 |
| Aaserud, O | 1 |
| Sortland, O | 1 |
| Nyberg-Hansen, R | 1 |
| Louwaege, A | 1 |
| Goubau, J | 1 |
| Deldycke, H | 1 |
| Brugman, E | 1 |
| Friberg, J | 1 |
| Gheysen, F | 1 |
| Deryckere, P | 1 |
| Herpels, V | 1 |
| Pedersen, ON | 1 |
| Vad, VB | 1 |
| Bhat, AL | 1 |
| Lutz, GE | 1 |
| Cammisa, F | 1 |
| Floras, P | 1 |
| Deliac, P | 1 |
| Gross, C | 1 |
| Jouet, P | 1 |
| Paty, J | 1 |
| Caille, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of the Efficacy Between Transforaminal Steroid Epidural Injection and Epidural Neuroplasty for the Treatment of Herniated Lumbar Disc：A Single Center, Controlled Clinical Trial[NCT03101033] | 92 participants (Actual) | Interventional | 2015-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at one-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 29.11 |
| Transforaminal Steroid Injection Group | 35.02 |
ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at six-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 30.52 |
| Transforaminal Steroid Injection Group | 46.39 |
ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at three-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 28.93 |
| Transforaminal Steroid Injection Group | 39.82 |
ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: before treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 53.85 |
| Transforaminal Steroid Injection Group | 57.84 |
VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at one-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 2.37 |
| Transforaminal Steroid Injection Group | 2.35 |
VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at six-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 2.81 |
| Transforaminal Steroid Injection Group | 4.06 |
VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at three-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 2.19 |
| Transforaminal Steroid Injection Group | 3.25 |
VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: before treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 5.63 |
| Transforaminal Steroid Injection Group | 5.92 |
3 trials available for iohexol and Sciatica
| Article | Year |
|---|---|
Documentation of a new contrast medium for the subarachnoid space. Demands, design and results from the first multicentre trial with iohexol.
Topics: Adult; Aged; Blood Cell Count; Clinical Trials as Topic; Contrast Media; Electroencephalography; Hea | 1983 |
Use of a 22-gauge Whitacre needle to reduce the incidence of side effects after lumbar myelography: a prospective randomised study comparing Whitacre and Quincke spinal needles.
Topics: Adult; Aged; Contrast Media; Dizziness; Dura Mater; Equipment Design; Female; Headache; Humans; Inci | 1996 |
Transforaminal epidural steroid injections in lumbosacral radiculopathy: a prospective randomized study.
Topics: Adult; Anesthetics, Local; Betamethasone; Contrast Media; Fluoroscopy; Follow-Up Studies; Hospitals, | 2002 |
3 other studies available for iohexol and Sciatica
| Article | Year |
|---|---|
Functional lumbar myelography with iohexol.
Topics: Adult; Aged; Contrast Media; Drug Evaluation; Female; Headache; Humans; Intervertebral Disc Displace | 1983 |
Efficiency of discography followed by chemonucleolysis in the treatment of sciatica.
Topics: Adolescent; Adult; Aged; Chymopapain; Contrast Media; Female; Humans; Intervertebral Disc; Intervert | 1996 |
Neurotoxicity of iohexol vs iopamidol in lumbar myelography. Clinical, electrophysiological and brain CT scan correlations.
Topics: Brain; Electroencephalography; Female; Headache; Humans; Iohexol; Iopamidol; Lumbosacral Region; Mal | 1990 |