Page last updated: 2024-10-29

iohexol and Sciatica

iohexol has been researched along with Sciatica in 6 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Sciatica: A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of SCIATIC NEUROPATHY; RADICULOPATHY (involving the SPINAL NERVE ROOTS; L4, L5, S1, or S2, often associated with INTERVERTEBRAL DISK DISPLACEMENT); or lesions of the CAUDA EQUINA.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grönneröd, TA1
Eldevik, OP1
Hindmarsh, T1
Kendall, B1
Nakstad, PH1
Nakstad, P1
Aaserud, O1
Sortland, O1
Nyberg-Hansen, R1
Louwaege, A1
Goubau, J1
Deldycke, H1
Brugman, E1
Friberg, J1
Gheysen, F1
Deryckere, P1
Herpels, V1
Pedersen, ON1
Vad, VB1
Bhat, AL1
Lutz, GE1
Cammisa, F1
Floras, P1
Deliac, P1
Gross, C1
Jouet, P1
Paty, J1
Caille, JM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Efficacy Between Transforaminal Steroid Epidural Injection and Epidural Neuroplasty for the Treatment of Herniated Lumbar Disc:A Single Center, Controlled Clinical Trial[NCT03101033]92 participants (Actual)Interventional2015-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Functional Status Assessed by Oswestry Disability Index

ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at one-month post-treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group29.11
Transforaminal Steroid Injection Group35.02

Functional Status Assessed by Oswestry Disability Index

ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at six-month post-treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group30.52
Transforaminal Steroid Injection Group46.39

Functional Status Assessed by Oswestry Disability Index

ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at three-month post-treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group28.93
Transforaminal Steroid Injection Group39.82

Functional Status Assessed by Oswestry Disability Index

ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: before treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group53.85
Transforaminal Steroid Injection Group57.84

Pain Assessed by Visual Analogue Scale

VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at one-month post-treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group2.37
Transforaminal Steroid Injection Group2.35

Pain Assessed by Visual Analogue Scale

VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at six-month post-treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group2.81
Transforaminal Steroid Injection Group4.06

Pain Assessed by Visual Analogue Scale

VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at three-month post-treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group2.19
Transforaminal Steroid Injection Group3.25

Pain Assessed by Visual Analogue Scale

VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: before treatment

Interventionunits on a scale (Mean)
Epidural Neuroplasty Group5.63
Transforaminal Steroid Injection Group5.92

Trials

3 trials available for iohexol and Sciatica

ArticleYear
Documentation of a new contrast medium for the subarachnoid space. Demands, design and results from the first multicentre trial with iohexol.
    Acta radiologica: diagnosis, 1983, Volume: 24, Issue:6

    Topics: Adult; Aged; Blood Cell Count; Clinical Trials as Topic; Contrast Media; Electroencephalography; Hea

1983
Use of a 22-gauge Whitacre needle to reduce the incidence of side effects after lumbar myelography: a prospective randomised study comparing Whitacre and Quincke spinal needles.
    European radiology, 1996, Volume: 6, Issue:2

    Topics: Adult; Aged; Contrast Media; Dizziness; Dura Mater; Equipment Design; Female; Headache; Humans; Inci

1996
Transforaminal epidural steroid injections in lumbosacral radiculopathy: a prospective randomized study.
    Spine, 2002, Jan-01, Volume: 27, Issue:1

    Topics: Adult; Anesthetics, Local; Betamethasone; Contrast Media; Fluoroscopy; Follow-Up Studies; Hospitals,

2002

Other Studies

3 other studies available for iohexol and Sciatica

ArticleYear
Functional lumbar myelography with iohexol.
    Acta radiologica: diagnosis, 1983, Volume: 24, Issue:6

    Topics: Adult; Aged; Contrast Media; Drug Evaluation; Female; Headache; Humans; Intervertebral Disc Displace

1983
Efficiency of discography followed by chemonucleolysis in the treatment of sciatica.
    Journal belge de radiologie, 1996, Volume: 79, Issue:2

    Topics: Adolescent; Adult; Aged; Chymopapain; Contrast Media; Female; Humans; Intervertebral Disc; Intervert

1996
Neurotoxicity of iohexol vs iopamidol in lumbar myelography. Clinical, electrophysiological and brain CT scan correlations.
    Journal of neuroradiology = Journal de neuroradiologie, 1990, Volume: 17, Issue:3

    Topics: Brain; Electroencephalography; Female; Headache; Humans; Iohexol; Iopamidol; Lumbosacral Region; Mal

1990