Page last updated: 2024-10-29

iohexol and Proteinuria

iohexol has been researched along with Proteinuria in 9 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"Histologic, functional (creatinine clearance), and biochemical (proteinuria and enzymuria) profiles of iohexol and iobitridol (both at 350 mg I/mL) were compared in the uninephrectomized rat."3.69Iobitridol, a new nonionic low-osmolality contrast agent, and iohexol. Impact on renal histology in the rat. ( Balut, C; Beaufils, H; Berthommier, C; Bonnemain, B; Bourbouze, R; Chicandre-Jouanneau, C; Idée, JM; Nimier, K, 1995)
"Pretreatment with nitrendipine did not reduce enzyme excretion, although AAP levels were lower in general in the group assigned to the 20-mg dose."2.68Dose effect of nitrendipine on urinary enzymes and microproteins following non-ionic radiocontrast administration. ( Artero, M; Carraro, M; Cova, M; Faccini, L; Grotto, M; Mancini, W; Stacul, F, 1996)
"In patients with liver cirrhosis a urine protein:creatinine ratio >30 predicts AKI."1.39Predicting the development of acute kidney injury in liver cirrhosis--an analysis of glomerular filtration rate, proteinuria and kidney injury biomarkers. ( Auzinger, G; Bernal, W; Bruce, M; Dew, T; Heneghan, MA; McPhail, MJ; Moore, K; Musto, R; O'Grady, J; Ostermann, M; Sherwood, R; Slack, AJ; Wendon, JA, 2013)
"Proteinuria was in the nephrotic range in 44 and the BMI exceeded the 95th percentile in 57 patients of this cohort."1.36Dyslipidemia in children with chronic kidney disease. ( Flynn, JT; Furth, SL; Goebel, J; Kupferman, JC; Mitsnefes, MM; Pierce, CB; Saland, JM; Warady, BA, 2010)
"Proteinuria is associated with chronic kidney disease (CKD), and heavy proteinuria predicts a rapid decline in kidney function."1.35Association of proteinuria with race, cause of chronic kidney disease, and glomerular filtration rate in the chronic kidney disease in children study. ( Benador, NM; Cole, SR; Furth, SL; Kaskel, F; Mak, RH; Pierce, CB; Schwartz, GJ; Warady, BA; Wong, CS, 2009)
"Hypertension was present in 38% of the donors but the age-adjusted prevalence of hypertension among donors was not higher than in the general population."1.31No evidence of accelerated loss of kidney function in living kidney donors: results from a cross-sectional follow-up. ( Brink, B; Dunér, F; Elinder, CG; Fehrman-Ekholm, I; Tydén, G, 2001)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's2 (22.22)18.2507
2000's4 (44.44)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Slack, AJ1
McPhail, MJ1
Ostermann, M1
Bruce, M1
Sherwood, R1
Musto, R1
Dew, T1
Auzinger, G1
Bernal, W1
O'Grady, J1
Heneghan, MA1
Moore, K1
Wendon, JA1
Wong, CS1
Pierce, CB2
Cole, SR1
Warady, BA2
Mak, RH1
Benador, NM1
Kaskel, F1
Furth, SL2
Schwartz, GJ1
Schaefer, F1
Saland, JM1
Mitsnefes, MM1
Flynn, JT1
Goebel, J1
Kupferman, JC1
Gruber, SJ1
Shapiro, CJ1
Beaufils, H1
Idée, JM1
Berthommier, C1
Balut, C1
Bourbouze, R1
Nimier, K1
Chicandre-Jouanneau, C1
Bonnemain, B1
Carraro, M1
Mancini, W1
Artero, M1
Stacul, F1
Grotto, M1
Cova, M1
Faccini, L1
Fehrman-Ekholm, I1
Dunér, F1
Brink, B1
Tydén, G1
Elinder, CG1
Kennedy, C1
Rickards, D1
Lee, S1
Sharp, MB1
Dawson, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)[NCT00327860]1,100 participants (Actual)Observational2003-10-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for iohexol and Proteinuria

ArticleYear
Dose effect of nitrendipine on urinary enzymes and microproteins following non-ionic radiocontrast administration.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:3

    Topics: Acetylglucosaminidase; Acute Kidney Injury; Aged; Albuminuria; Alpha-Globulins; Angiography, Digital

1996
A double-blind study comparing the efficiency, tolerance and renal effects of iopromide and iopamidol.
    The British journal of radiology, 1988, Volume: 61, Issue:724

    Topics: Clinical Trials as Topic; Contrast Media; Double-Blind Method; Female; Humans; Iohexol; Iopamidol; K

1988

Other Studies

7 other studies available for iohexol and Proteinuria

ArticleYear
Predicting the development of acute kidney injury in liver cirrhosis--an analysis of glomerular filtration rate, proteinuria and kidney injury biomarkers.
    Alimentary pharmacology & therapeutics, 2013, Volume: 37, Issue:10

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Adult; Aged; Biomarkers; Cohort Studies; Contrast Media;

2013
Association of proteinuria with race, cause of chronic kidney disease, and glomerular filtration rate in the chronic kidney disease in children study.
    Clinical journal of the American Society of Nephrology : CJASN, 2009, Volume: 4, Issue:4

    Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Black

2009
Proteinuria: not a small problem in the little ones.
    Clinical journal of the American Society of Nephrology : CJASN, 2009, Volume: 4, Issue:4

    Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Black

2009
Dyslipidemia in children with chronic kidney disease.
    Kidney international, 2010, Volume: 78, Issue:11

    Topics: Adolescent; Age Factors; Biomarkers; Body Mass Index; Chi-Square Distribution; Child; Child, Prescho

2010
Nephropathy induced by contrast medium.
    The New England journal of medicine, 2003, May-29, Volume: 348, Issue:22

    Topics: Angiotensin-Converting Enzyme Inhibitors; Confounding Factors, Epidemiologic; Contrast Media; Creati

2003
Iobitridol, a new nonionic low-osmolality contrast agent, and iohexol. Impact on renal histology in the rat.
    Investigative radiology, 1995, Volume: 30, Issue:1

    Topics: Acetylglucosaminidase; Animals; Contrast Media; Creatinine; Iohexol; Kidney; Male; Proteinuria; Rats

1995
No evidence of accelerated loss of kidney function in living kidney donors: results from a cross-sectional follow-up.
    Transplantation, 2001, Aug-15, Volume: 72, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Cross-Sectional Studies; Female; Follow-Up Studies;

2001