Page last updated: 2024-10-29

iohexol and Pancreatitis

iohexol has been researched along with Pancreatitis in 31 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.

Research Excerpts

ExcerptRelevanceReference
"We previously described the association of pancreatitis with the use of iodixanol radiocontrast in two patients on hemodialysis."9.14Pancreatitis following administration of iodixanol in patients on hemodialysis: a pilot study. ( Brenner, L; Kheda, M; Kota, V; Riggans, D; Szerlip, HM, 2010)
"Post-ERCP pancreatitis was diagnosed in 2 patients in the iopromid group and in 5 patients in the iotrolan group."6.69Frequency of pancreatitis after endoscopic retrograde cholangiopancreatography with iopromid or iotrolan: a randomized trial. ( Doppl, W; Goebel, C; Hackstein, N; Hardt, P; Klör, HU; Temme, H, 2000)
"We previously described the association of pancreatitis with the use of iodixanol radiocontrast in two patients on hemodialysis."5.14Pancreatitis following administration of iodixanol in patients on hemodialysis: a pilot study. ( Brenner, L; Kheda, M; Kota, V; Riggans, D; Szerlip, HM, 2010)
"We exposed mouse and human acinar cells to the radiocontrast agent iohexol (Omnipaque; GE Healthcare, Princeton, NJ) and measured intracellular release of Ca(2+), calcineurin activation (using a luciferase reporter), activation of nuclear factor-κB (NF-κB, using a luciferase reporter), and cell necrosis (via propidium iodide uptake)."3.81Exposure to Radiocontrast Agents Induces Pancreatic Inflammation by Activation of Nuclear Factor-κB, Calcium Signaling, and Calcineurin. ( Bottino, R; Eisses, JF; Husain, SZ; Javed, TA; Jin, S; Le, T; Molkentin, JD; Orabi, AI; Sah, S, 2015)
", with graft pancreatitis, were injected with iopromide."3.74Hemodynamic effect of iopromide in pancreas-duodenum transplanted rats. ( Carlsson, PO; Hansell, P; Jansson, L; Källskog, Ö; Linder, G; Riesenfeld Källskog, V, 2007)
"Post-ERCP pancreatitis was diagnosed in 2 patients in the iopromid group and in 5 patients in the iotrolan group."2.69Frequency of pancreatitis after endoscopic retrograde cholangiopancreatography with iopromid or iotrolan: a randomized trial. ( Doppl, W; Goebel, C; Hackstein, N; Hardt, P; Klör, HU; Temme, H, 2000)
"Pancreatitis is a major cause of morbidity and mortality secondary to endoscopic retrograde pancreatography (ERP)."2.67A comparative study of contrast agents for endoscopic retrograde pancreatography. ( Barkin, JS; Casal, GL; Goldberg, RI; Kaplan, S; Phillips, RS; Reiner, DK, 1991)
"Seventy patients with acute pancreatitis (AP) confirmed by clinical examination were included in this study."1.62The value of a dual-energy spectral CT quantitative analysis technique in acute pancreatitis. ( Hu, X; Wei, W; Zhang, L, 2021)
"All patients had early multiple organ failure and subsequently died."1.34Intense adrenal enhancement in patients with acute pancreatitis and early organ failure. ( Besselink, MG; Bollen, TL; Gooszen, HG; van Es, HW; van Ramshorst, B; van Santvoort, HC, 2007)
"Pancreatitis is the most frequent complication of endoscopic retrograde cholangiopancreatography."1.33Comparison of the effect of non-ionic and ionic contrast agents on pancreatic histology in a canine model. ( Eckoff, D; Fischer, MC; Gopal, DV; Lee, FT; Mosley, RG; Oberley, T; Pfau, PR; Reichelderfer, M; Said, A; Weiss, J, 2006)
"We report a 30-year-old patient with the acquired immunodeficiency syndrome in whom pancreatitis was exacerbated by oral and IV contrast medium and also by IV lipid emulsion in the absence of hypertriglyceridemia."1.32Association of pancreatitis with administration of contrast medium and intravenous lipid emulsion in a patient with the acquired immunodeficiency syndrome. ( Estrada, CA; Kasi, VS; Wiese, W, 2003)
"When histologic fibrosis is uniformly present through the pancreas in patients with chronic pancreatitis, there is no demarcation of masses due to chronic pancreatitis."1.31Pancreatic mass due to chronic pancreatitis: correlation of CT and MR imaging features with pathologic findings. ( Hori, M; Kim, T; Murakami, T; Nakamori, S; Nakamura, H; Sakon, M; Takahashi, S; Takamura, M; Tanji, Y; Wakasa, K, 2001)
"Most studies of the adverse effects of x-ray contrast media used in ERCP have focused on post-ERCP pancreatitis."1.31Comparative cytotoxicity of low-osmolar nonionic and high-osmolar ionic contrast media to dog gallbladder epithelial cells. ( Ju, YM; Kim, JY; Kim, MH; Lee, SK; Min, YI; Seo, DW, 2002)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.45)18.7374
1990's8 (25.81)18.2507
2000's9 (29.03)29.6817
2010's9 (29.03)24.3611
2020's3 (9.68)2.80

Authors

AuthorsStudies
Gupta, P1
Dawra, S1
Chandel, K1
Samanta, J1
Mandavdhare, H1
Sharma, V1
Sinha, SK1
Dutta, U1
Kochhar, R1
Ren, S1
Zhao, R1
Zhang, J1
Guo, K1
Gu, X1
Duan, S1
Wang, Z1
Chen, R1
Hu, X1
Wei, W1
Zhang, L1
Choi, HW1
Park, HJ1
Choi, SY1
Do, JH1
Yoon, NY1
Ko, A1
Lee, ES1
Tsuji, Y1
Takahashi, N1
Fletcher, JG1
Hough, DM1
McMenomy, BP1
Lewis, DM1
Vege, SS1
Chari, ST1
McCollough, CH1
Grant, KL1
Klotz, E1
Woods, RW1
Akshintala, VS1
Singh, VK1
Almulla, A1
Khan, VN1
Cader, R1
Fishman, EK1
Zaheer, A1
Jin, S1
Orabi, AI1
Le, T1
Javed, TA1
Sah, S1
Eisses, JF1
Bottino, R1
Molkentin, JD1
Husain, SZ1
Yamada, Y1
Mori, H1
Matsumoto, S1
Kiyosue, H1
Hori, Y1
Hongo, N1
Testoni, PA1
Mariani, A1
Giussani, A1
Vailati, C1
Masci, E1
Macarri, G1
Ghezzo, L1
Familiari, L1
Giardullo, N1
Mutignani, M1
Lombardi, G1
Talamini, G1
Spadaccini, A1
Briglia, R1
Piazzi, L1
Kheda, M1
Brenner, L1
Riggans, D1
Kota, V1
Szerlip, HM1
Schott, P1
Kurtz, B1
Asayama, Y1
Fang, W1
Stolpen, A1
Kuehn, D1
Kasi, VS1
Estrada, CA1
Wiese, W1
George, S1
Kulkarni, AA1
Stevens, G1
Forsmark, CE1
Draganov, P1
Pfau, PR1
Mosley, RG1
Said, A1
Gopal, DV1
Fischer, MC1
Oberley, T1
Weiss, J1
Lee, FT1
Eckoff, D1
Reichelderfer, M1
Bollen, TL1
van Santvoort, HC1
Besselink, MG1
van Ramshorst, B1
van Es, HW1
Gooszen, HG1
Linder, G1
Carlsson, PO1
Källskog, Ö1
Hansell, P1
Jansson, L1
Riesenfeld Källskog, V1
Manfredi, R1
Graziani, R1
Cicero, C1
Frulloni, L1
Carbognin, G1
Mantovani, W1
Mucelli, RP1
Zeitler, E1
Böhnlein, K1
Gailer, H1
Lindner, R1
Richter, EI1
Goebel, C1
Hardt, P1
Doppl, W1
Temme, H1
Hackstein, N1
Klör, HU1
Kim, T1
Murakami, T1
Takamura, M1
Hori, M1
Takahashi, S1
Nakamori, S1
Sakon, M1
Tanji, Y1
Wakasa, K1
Nakamura, H1
Ju, YM1
Kim, MH1
Lee, SK1
Seo, DW1
Min, YI1
Kim, JY1
Poulton, TB1
Rauchenstein, JN1
Murphy, WD1
Tervahartiala, P2
Kivisaari, L2
Kivisaari, R2
Virtanen, I2
Short, TP1
Thomas, E1
Cotton, PB1
Brazer, SR1
Banerjee, A1
Barkin, JS1
Casal, GL1
Reiner, DK1
Goldberg, RI1
Phillips, RS1
Kaplan, S1
Banerjee, AK1
Grainger, SL1
Thompson, RP1
Saari, A1
Standertskjöld-Nordenstam, CG1
Brackett, K1
Schröder, T1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Different Length of Time for Trainees to Attempt Cannulation on Success Rate of Selective Cannulation During hands-on ERCP Training[NCT01851226]256 participants (Actual)Interventional2013-05-31Completed
A Randomized Trial Comparing Rectal Indomethacin Alone Versus a Combination of Rectal Indomethacin and Oral Tacrolimus for Post-ERCP Pancreatitis Prophylaxis[NCT05252754]Phase 34,874 participants (Anticipated)Interventional2023-01-18Recruiting
Effects of High Intra-procedural Oxygen Fraction on Post-ERCP Pancreatitis: A Randomized Clinical Trial[NCT04876768]25 participants (Actual)Interventional2021-05-18Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for iohexol and Pancreatitis

ArticleYear
Role of osmolality of contrast media in the development of post-ERCP pancreatitis: a metanalysis.
    Digestive diseases and sciences, 2004, Volume: 49, Issue:3

    Topics: Cholangiopancreatography, Endoscopic Retrograde; Contrast Media; Humans; Iohexol; Ioxaglic Acid; Log

2004

Trials

4 trials available for iohexol and Pancreatitis

ArticleYear
Pancreatitis following administration of iodixanol in patients on hemodialysis: a pilot study.
    Clinical nephrology, 2010, Volume: 73, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Amylases; Contrast Media; Female; Humans; Iohexol; Kidney Failure, C

2010
Frequency of pancreatitis after endoscopic retrograde cholangiopancreatography with iopromid or iotrolan: a randomized trial.
    European radiology, 2000, Volume: 10, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Cholangiopancreatography, Endoscopic Retrograde; Contrast Media; Dou

2000
A comparative study of contrast agents for endoscopic retrograde pancreatography.
    The American journal of gastroenterology, 1991, Volume: 86, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cholangiopancreatography, Endoscopic Retrograde; Diatriz

1991
Trial of low versus high osmolar contrast media in endoscopic retrograde cholangiopancreatography.
    The British journal of clinical practice, 1990, Volume: 44, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Cholangiopancreatography, Endoscopic Retrograde; Contrast Media; Dia

1990

Other Studies

26 other studies available for iohexol and Pancreatitis

ArticleYear
Fat-modified computed tomography severity index (CTSI) is a better predictor of severity and outcome in patients with acute pancreatitis compared with modified CTSI.
    Abdominal radiology (New York), 2020, Volume: 45, Issue:5

    Topics: Adult; Contrast Media; Drainage; Female; Humans; Intra-Abdominal Fat; Iohexol; Length of Stay; Male;

2020
Diagnostic accuracy of unenhanced CT texture analysis to differentiate mass-forming pancreatitis from pancreatic ductal adenocarcinoma.
    Abdominal radiology (New York), 2020, Volume: 45, Issue:5

    Topics: Adult; Aged; Algorithms; Carcinoma, Pancreatic Ductal; Contrast Media; Diagnosis, Differential; Fema

2020
The value of a dual-energy spectral CT quantitative analysis technique in acute pancreatitis.
    Clinical radiology, 2021, Volume: 76, Issue:7

    Topics: Adult; Aged; Contrast Media; Female; Humans; Iohexol; Male; Middle Aged; Pancreatitis; Retrospective

2021
Early Prediction of the Severity of Acute Pancreatitis Using Radiologic and Clinical Scoring Systems With Classification Tree Analysis.
    AJR. American journal of roentgenology, 2018, Volume: 211, Issue:5

    Topics: Acute Disease; APACHE; Contrast Media; Decision Trees; Female; Humans; Iohexol; Iopamidol; Male; Mid

2018
Subtraction color map of contrast-enhanced and unenhanced CT for the prediction of pancreatic necrosis in early stage of acute pancreatitis.
    AJR. American journal of roentgenology, 2014, Volume: 202, Issue:4

    Topics: APACHE; Color; Contrast Media; Female; Humans; Imaging, Three-Dimensional; Iohexol; Length of Stay;

2014
CT severity of post-ERCP pancreatitis: results from a single tertiary medical center.
    Abdominal imaging, 2014, Volume: 39, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Cholangiopancreatography, Endoscopic Retrograd

2014
Exposure to Radiocontrast Agents Induces Pancreatic Inflammation by Activation of Nuclear Factor-κB, Calcium Signaling, and Calcineurin.
    Gastroenterology, 2015, Volume: 149, Issue:3

    Topics: Animals; Calcineurin; Calcineurin Inhibitors; Calcium Signaling; Chlorocebus aethiops; Contrast Medi

2015
Pancreatic adenocarcinoma versus chronic pancreatitis: differentiation with triple-phase helical CT.
    Abdominal imaging, 2010, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Chronic Disease; Contrast M

2010
Risk factors for post-ERCP pancreatitis in high- and low-volume centers and among expert and non-expert operators: a prospective multicenter study.
    The American journal of gastroenterology, 2010, Volume: 105, Issue:8

    Topics: Adult; Aged; Chi-Square Distribution; Cholangiopancreatography, Endoscopic Retrograde; Clinical Comp

2010
Risk factors for post-ERCP pancreatitis in high- and low-volume centers and among expert and non-expert operators: a prospective multicenter study.
    The American journal of gastroenterology, 2010, Volume: 105, Issue:8

    Topics: Adult; Aged; Chi-Square Distribution; Cholangiopancreatography, Endoscopic Retrograde; Clinical Comp

2010
Risk factors for post-ERCP pancreatitis in high- and low-volume centers and among expert and non-expert operators: a prospective multicenter study.
    The American journal of gastroenterology, 2010, Volume: 105, Issue:8

    Topics: Adult; Aged; Chi-Square Distribution; Cholangiopancreatography, Endoscopic Retrograde; Clinical Comp

2010
Risk factors for post-ERCP pancreatitis in high- and low-volume centers and among expert and non-expert operators: a prospective multicenter study.
    The American journal of gastroenterology, 2010, Volume: 105, Issue:8

    Topics: Adult; Aged; Chi-Square Distribution; Cholangiopancreatography, Endoscopic Retrograde; Clinical Comp

2010
Risk factors for post-ERCP pancreatitis in high- and low-volume centers and among expert and non-expert operators: a prospective multicenter study.
    The American journal of gastroenterology, 2010, Volume: 105, Issue:8

    Topics: Adult; Aged; Chi-Square Distribution; Cholangiopancreatography, Endoscopic Retrograde; Clinical Comp

2010
Risk factors for post-ERCP pancreatitis in high- and low-volume centers and among expert and non-expert operators: a prospective multicenter study.
    The American journal of gastroenterology, 2010, Volume: 105, Issue:8

    Topics: Adult; Aged; Chi-Square Distribution; Cholangiopancreatography, Endoscopic Retrograde; Clinical Comp

2010
Risk factors for post-ERCP pancreatitis in high- and low-volume centers and among expert and non-expert operators: a prospective multicenter study.
    The American journal of gastroenterology, 2010, Volume: 105, Issue:8

    Topics: Adult; Aged; Chi-Square Distribution; Cholangiopancreatography, Endoscopic Retrograde; Clinical Comp

2010
Risk factors for post-ERCP pancreatitis in high- and low-volume centers and among expert and non-expert operators: a prospective multicenter study.
    The American journal of gastroenterology, 2010, Volume: 105, Issue:8

    Topics: Adult; Aged; Chi-Square Distribution; Cholangiopancreatography, Endoscopic Retrograde; Clinical Comp

2010
Risk factors for post-ERCP pancreatitis in high- and low-volume centers and among expert and non-expert operators: a prospective multicenter study.
    The American journal of gastroenterology, 2010, Volume: 105, Issue:8

    Topics: Adult; Aged; Chi-Square Distribution; Cholangiopancreatography, Endoscopic Retrograde; Clinical Comp

2010
[Lipoma of the spleen].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2011, Volume: 183, Issue:9

    Topics: Acute Disease; Cholangiopancreatography, Magnetic Resonance; Contrast Media; Diagnosis, Differential

2011
Detectability of pancreas divisum in patients with acute pancreatitis on multi-detector row computed tomography.
    Emergency radiology, 2012, Volume: 19, Issue:2

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Cholangiopancreatography, Endoscopic Retrograde; Cont

2012
Association of pancreatitis with administration of contrast medium and intravenous lipid emulsion in a patient with the acquired immunodeficiency syndrome.
    Southern medical journal, 2003, Volume: 96, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; Contrast Media; Fat Emulsions, Intravenous

2003
Comparison of the effect of non-ionic and ionic contrast agents on pancreatic histology in a canine model.
    JOP : Journal of the pancreas, 2006, Jan-11, Volume: 7, Issue:1

    Topics: Amylases; Animals; Cholangiopancreatography, Endoscopic Retrograde; Contrast Media; Diatrizoate; Dog

2006
Intense adrenal enhancement in patients with acute pancreatitis and early organ failure.
    Emergency radiology, 2007, Volume: 14, Issue:5

    Topics: Acute Disease; Adrenal Glands; Aged; Contrast Media; Female; Humans; Iohexol; Multiple Organ Failure

2007
Hemodynamic effect of iopromide in pancreas-duodenum transplanted rats.
    Acta radiologica (Stockholm, Sweden : 1987), 2007, Volume: 48, Issue:10

    Topics: Animals; Contrast Media; Duodenum; Iohexol; Male; Pancreas; Pancreas Transplantation; Pancreatitis;

2007
Autoimmune pancreatitis: CT patterns and their changes after steroid treatment.
    Radiology, 2008, Volume: 247, Issue:2

    Topics: Adult; Aged; Autoimmune Diseases; Contrast Media; Diatrizoate Meglumine; Female; Glucocorticoids; Hu

2008
Experiences with rayvist and iopromid in head and body CT.
    Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. Erganzungsband, 1983, Volume: 118

    Topics: Acute Disease; Contrast Media; Humans; Iodobenzoates; Iohexol; Iothalamic Acid; Kidney Neoplasms; Pa

1983
Pancreatic mass due to chronic pancreatitis: correlation of CT and MR imaging features with pathologic findings.
    AJR. American journal of roentgenology, 2001, Volume: 177, Issue:2

    Topics: Adenocarcinoma; Chronic Disease; Contrast Media; Diagnosis, Differential; Female; Fibrosis; Humans;

2001
Comparative cytotoxicity of low-osmolar nonionic and high-osmolar ionic contrast media to dog gallbladder epithelial cells.
    Gastrointestinal endoscopy, 2002, Volume: 55, Issue:3

    Topics: Aneuploidy; Animals; Cell Count; Cell Cycle; Cholangiopancreatography, Endoscopic Retrograde; Cholan

2002
Diffuse liver and splenic activity with Tc-99m MDP associated with iohexol injection. A case report.
    Clinical nuclear medicine, 1992, Volume: 17, Issue:11

    Topics: Aged; Bone and Bones; Colloids; Female; Humans; Iohexol; Liver; Pancreatitis; Radiography, Abdominal

1992
Contrast media-induced renal morphologic lesions during experimental hemorrhagic necrotizing pancreatitis.
    Investigative radiology, 1992, Volume: 27, Issue:12

    Topics: Animals; Contrast Media; Diatrizoate; Female; Gadolinium DTPA; Hemorrhage; Iohexol; Kidney; Male; Ne

1992
Different contrast agents and development of pancreatitis after endoscopic retrograde pancreatography.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:5

    Topics: Cholangiopancreatography, Endoscopic Retrograde; Contrast Media; Diatrizoate; Humans; Iohexol; Ioxag

1992
Different contrast agents and development of pancreatitis after endoscopic retrograde pancreatography.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:5

    Topics: Cholangiopancreatography, Endoscopic Retrograde; Contrast Media; Diatrizoate; Humans; Iohexol; Pancr

1992
Different contrast agents and development of pancreatitis after endoscopic retrograde pancreatography.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:5

    Topics: Cholangiopancreatography, Endoscopic Retrograde; Contrast Media; Diatrizoate Meglumine; Humans; Iohe

1992
Contrast media-induced renal morphologic changes in rats with acute edematous pancreatitis.
    Investigative radiology, 1992, Volume: 27, Issue:7

    Topics: Acute Disease; Animals; Contrast Media; Diatrizoate; Female; Gadolinium DTPA; Injections, Intravenou

1992
Experimental pancreatography: a comparison of three contrast media.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:1

    Topics: Animals; Cholangiopancreatography, Endoscopic Retrograde; Diatrizoate Meglumine; Iohexol; Ioxaglic A

1988