iohexol has been researched along with Pain in 31 studies
Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two low-osmolality contrast agents, ioxaglate meglumine/sodium and iohexol were compared with diatrizoate meglumine/sodium in a controlled double blind study of 126 patients undergoing arteriography for peripheral vascular disease to determine which caused the least pain." | 5.06 | Pain in peripheral arteriography: an assessment of conventional versus ionic and non-ionic low-osmolality contrast agents. ( Campbell, DR; Fraser, DB; Murphy, G, 1988) |
| "Comparing iohexol 240 mg I/ml, iohexol 300 mg I/ml and meglumine-Ca metrizoate 200 mg I/ml in phlebography of the leg in patients on or without anticoagulants, no sign of post-phlebographic thrombosis was found using the 125I-fibrinogen uptake test and repeat phlebography." | 5.05 | Iohexol in phlebography of the leg. A comparative investigation with meglumine metrizoate. ( Andrew, E; Enge, I; Gjølberg, T, 1983) |
| "Two non-ionic contrast media, iohexol and metrizamide, were compared in a double-blind clinical trial which included 50 patients who underwent lumbar myelography for disc herniation or spinal stenosis." | 5.05 | Lumbar myelography with iohexol and metrizamide. A double-blind clinical trial. ( Ekholm, SE; Hindmarsh, T; Kido, DK; Sahler, L; Sands, M, 1984) |
| "), elicit a pain response comparable to that caused by bradykinin (BK) or capsaicin (CAP)." | 3.68 | Mechanism of pain induced by radiocontrast media. ( Antunes, E; Ballejo, G; Corrado, AP; de Nucci, G, 1992) |
| "Lumbar myelography with iohexol (Omnipaque) was performed in 103 consecutive adult patients with low back pain or sciatica." | 3.67 | Lumbar myelography with Omnipaque (iohexol). ( Bach-Gansmo, T; Lilleås, F; Weber, H, 1986) |
| "Heat and pain were scored on visual analog scales." | 2.68 | Iohexol vs. ioxaglate in lower extremity angiography: a comparative randomized double-blind study in 80 patients. ( Guit, GL; Krouwels, MM; Overbosch, EH, 1996) |
| " Safety was assessed by monitoring vital signs (blood pressure, pulse and respiration), clinical laboratory studies and observation of adverse effects prior to and after injection of contrast medium." | 2.67 | A double blind clinical study comparing the safety, tolerance and efficacy of ioversol 240 and iohexol 240 (Omnipaque 240) in ascending venography. ( Spinks, BC; Wilkins, RA, 1990) |
| "Iohexol was well tolerated in renal and visceral angiography." | 2.65 | Iohexol in lower extremity, renal and visceral angiography. Survey and present state. ( Kolbenstvedt, A, 1983) |
| "The incidence of post-myelogram headache was similar to that reported for inpatients." | 1.28 | Outpatient myelography: an acceptable and cost-effective technique. ( Barber, CJ; Choudhri, AH; Johnson, J; Rowlands, PC; Stevens, JM, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (48.39) | 18.7374 |
| 1990's | 14 (45.16) | 18.2507 |
| 2000's | 1 (3.23) | 29.6817 |
| 2010's | 1 (3.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kok, M | 1 |
| Mihl, C | 1 |
| Hendriks, BM | 1 |
| Altintas, S | 1 |
| Eijsvoogel, NG | 1 |
| Kietselaer, BL | 1 |
| Wildberger, JE | 1 |
| Das, M | 1 |
| D'Onofrio, M | 1 |
| Caffarri, S | 1 |
| Zamboni, G | 1 |
| Falconi, M | 1 |
| Mansueto, G | 1 |
| Valk, J | 1 |
| Crezée, F | 1 |
| Olislagers-de Slegte, RG | 1 |
| Kolbenstvedt, A | 1 |
| Cronqvist, S | 1 |
| Wolf, GL | 1 |
| Lea Thomas, M | 1 |
| Briggs, GM | 1 |
| Keeling, FP | 1 |
| Gjølberg, T | 1 |
| Andrew, E | 1 |
| Enge, I | 1 |
| Sackett, JF | 1 |
| Bergsjordet, B | 1 |
| Seeger, JF | 1 |
| Kieffer, SA | 1 |
| Hindmarsh, T | 1 |
| Ekholm, SE | 1 |
| Kido, DK | 2 |
| Sahler, L | 1 |
| Sands, M | 1 |
| Morris, TW | 1 |
| Ekholm, S | 1 |
| Plassche, W | 1 |
| Erickson, JL | 1 |
| Nyman, U | 1 |
| Nilsson, P | 1 |
| Westergren, A | 1 |
| Krause, W | 1 |
| Press, WR | 1 |
| Frenzel, T | 1 |
| Harding, JR | 1 |
| Bertazzoli, M | 1 |
| Spinazzi, A | 1 |
| Shinomiya, K | 1 |
| Nakao, K | 1 |
| Shindoh, S | 1 |
| Mochida, K | 1 |
| Furuya, K | 1 |
| Krouwels, MM | 1 |
| Overbosch, EH | 1 |
| Guit, GL | 1 |
| Cohan, RH | 1 |
| Bullard, MA | 1 |
| Ellis, JH | 1 |
| Jan, SC | 1 |
| Francis, IR | 1 |
| Garner, WL | 1 |
| Dunnick, NR | 1 |
| Corrado, AP | 1 |
| Ballejo, G | 1 |
| Antunes, E | 1 |
| de Nucci, G | 1 |
| Rieser, R | 1 |
| Beinborn, W | 1 |
| Ney, N | 1 |
| Wang, H | 1 |
| Kumar, AJ | 1 |
| Zinreich, SJ | 1 |
| Higgins, YM | 1 |
| Long, DM | 1 |
| Bryan, RN | 1 |
| Tallroth, K | 1 |
| Soini, J | 1 |
| Antti-Poika, I | 1 |
| Konttinen, YT | 1 |
| Honkanen, V | 1 |
| Yrjönen, T | 1 |
| Lindequist, S | 1 |
| Justesen, P | 1 |
| Larsen, C | 1 |
| Rasmussen, F | 1 |
| Ida, M | 1 |
| Kurabayashi, T | 1 |
| Ohbayashi, N | 1 |
| Honda, E | 1 |
| Sasaki, T | 1 |
| Berde, CB | 1 |
| Sethna, NF | 1 |
| Fisher, DE | 1 |
| Kahn, CH | 1 |
| Chandler, P | 1 |
| Grier, HE | 1 |
| Wilkins, RA | 1 |
| Spinks, BC | 1 |
| Billström, A | 1 |
| Hietala, SO | 1 |
| Sunnegårdh, O | 1 |
| Sjödin, JG | 1 |
| Wirell, S | 1 |
| Choudhri, AH | 1 |
| Rowlands, PC | 1 |
| Barber, CJ | 1 |
| Johnson, J | 1 |
| Stevens, JM | 1 |
| Murphy, G | 1 |
| Campbell, DR | 1 |
| Fraser, DB | 1 |
| Sovak, M | 1 |
| Halkovich, CA | 1 |
| Foster, SJ | 1 |
| Tajima, N | 1 |
| Lilleås, F | 1 |
| Bach-Gansmo, T | 1 |
| Weber, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Can Contrast Infused Sonography Using Air Bubbles Replace Hysterosalpingogram as the Diagnostic Evaluation of Fallopian Tube Patency Following Hysteroscopic Sterilization Using Essure[NCT02628873] | 21 participants (Actual) | Interventional | 2015-12-31 | Terminated (stopped due to Essure no longer sold in the US after Dec 2018; Sponsor requested trial be ended) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Observed image of uterus (normal or not normal). Assessor commented on uterine cavity to determine whether cavity was normal versus abnormal, e.g., bicornuate uterus or any notable uterine deformity. Data were coded as normal' or not normal." (NCT02628873)
Timeframe: At time of HyCoSy procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Arm 1 (HyCoSy Followed by HSG) | 13 |
| Arm 2 (HSG Followed by HyCoSy) | 6 |
Observed flow of fluid/bubbles through fallopian tubes. (NCT02628873)
Timeframe: At time of procedure
| Intervention | fallopian tubes observed to be closed (Count of Units) | |
|---|---|---|
| Number of tubes closed per first procedure | Number of tubes closed per second procedure | |
| Arm 1 (HyCoSy Followed by HSG) | 24 | 25 |
| Arm 2 (HSG Followed by HyCoSy) | 12 | 12 |
Patient reported pain scale score on visual pain scale (rated 0 for no pain to 10 for severe pain with corresponding faces) (NCT02628873)
Timeframe: At time of procedures
| Intervention | units on a scale (Mean) | |
|---|---|---|
| HSG post procedure pain score | HyCoSy post procedure pain score | |
| Arm 1 (HyCoSy Followed by HSG) | 1.4 | 2.4 |
| Arm 2 (HSG Followed by HyCoSy) | 1.8 | 2.3 |
18 trials available for iohexol and Pain
| Article | Year |
|---|---|
Patient Comfort During Contrast Media Injection in Coronary Computed Tomographic Angiography Using Varying Contrast Media Concentrations and Flow Rates: Results From the EICAR Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Computed Tomography Angiography; Contrast Media; Coronar | 2016 |
Comparison of iohexol 300 mg I/ml and Hexabrix 320 mg I/ml in central angiography. A double-blind trial.
Topics: Adult; Blood Pressure; Cerebral Angiography; Clinical Trials as Topic; Contrast Media; Double-Blind | 1984 |
Iohexol in lower extremity, renal and visceral angiography. Survey and present state.
Topics: Angiography; Blood Pressure; Clinical Trials as Topic; Contrast Media; Heart Rate; Humans; Iodobenzo | 1983 |
Iohexol in cerebral angiography. Survey and present state.
Topics: Blood Pressure; Central Nervous System Diseases; Cerebral Angiography; Clinical Trials as Topic; Con | 1983 |
Adult peripheral angiography. Results from four North American randomized clinical trials of ionic media versus iohexol.
Topics: Angiography; Blood Pressure; Clinical Trials as Topic; Contrast Media; Diatrizoate; Diatrizoate Megl | 1983 |
Iohexol and meglumine iothalamate in phlebography of the leg. Comparison of the tolerance.
Topics: Adult; Aged; Clinical Trials as Topic; Contrast Media; Double-Blind Method; Drug Tolerance; Edema; F | 1983 |
Iohexol in phlebography of the leg. A comparative investigation with meglumine metrizoate.
Topics: Adult; Aged; Anticoagulants; Clinical Trials as Topic; Contrast Media; Drug Tolerance; Female; Human | 1983 |
Digital subtraction angiography. Comparison of meglumine-Na diatrizoate with iohexol.
Topics: Adult; Aged; Angiography; Carotid Arteries; Clinical Trials as Topic; Contrast Media; Diatrizoate; D | 1983 |
Lumbar myelography with iohexol and metrizamide. A double-blind clinical trial.
Topics: Adolescent; Adult; Aged; Contrast Media; Double-Blind Method; Drug Evaluation; Female; Headache; Hum | 1984 |
Pain and hemodynamic effects in aortofemoral angiography. Clinical comparison of iohexol, ioxaglate and metrizamide.
Topics: Aged; Aortography; Blood Pressure; Contrast Media; Female; Femoral Artery; Heart Rate; Hemodynamics; | 1982 |
A randomized, double-blind, parallel group trial of iomeprol, iohexol and iopamidol in intravenous urography.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Contrast Media; Double-Blind Method; Female; Humans; Inj | 1995 |
Iohexol vs. ioxaglate in lower extremity angiography: a comparative randomized double-blind study in 80 patients.
Topics: Adult; Aged; Aged, 80 and over; Angiography; Contrast Media; Double-Blind Method; Female; Humans; Io | 1996 |
A double-blind comparative study on the contrast quality, tolerance and safety of ioversol 300 versus iohexol 300 in central venous angiography (C.V. DSA).
Topics: Adult; Aged; Aged, 80 and over; Angiography; Contrast Media; Double-Blind Method; Female; Humans; Hy | 1992 |
Diagnostic quality and complications of hysterosalpingography: oil- versus water-soluble contrast media--a randomized prospective study.
Topics: Contrast Media; Diatrizoate Meglumine; Ethiodized Oil; Extravasation of Diagnostic and Therapeutic M | 1991 |
Radiographic quality and patient discomfort in sialography: comparison of iohexol with iothalamate.
Topics: Adult; Chi-Square Distribution; Contrast Media; Double-Blind Method; Female; Humans; Iohexol; Iothal | 1991 |
A double blind clinical study comparing the safety, tolerance and efficacy of ioversol 240 and iohexol 240 (Omnipaque 240) in ascending venography.
Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Double-Blind Method; Female; Hot Temperature; Humans | 1990 |
Contrast media and pain in patients with acute ureteral stone obstruction. A comparative study with iohexol and metrizoate.
Topics: Adult; Aged; Female; Humans; Iohexol; Male; Metrizoic Acid; Middle Aged; Pain; Radiography; Ureteral | 1990 |
Pain in peripheral arteriography: an assessment of conventional versus ionic and non-ionic low-osmolality contrast agents.
Topics: Adult; Aged; Aged, 80 and over; Angiography; Clinical Trials as Topic; Contrast Media; Diatrizoate M | 1988 |
13 other studies available for iohexol and Pain
| Article | Year |
|---|---|
Contrast-enhanced ultrasonography in the characterization of pancreatic mucinous cystadenoma.
Topics: Adult; Contrast Media; Cystadenoma, Mucinous; Diagnosis, Differential; Female; Humans; Iohexol; Micr | 2004 |
Comparison of iohexol and meglumine-Na diatrizoate in cerebral angiography.
Topics: Blood Pressure; Cerebral Angiography; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Double-Bli | 1983 |
Preclinical testing of iopromide. 1st communication: pharmacological evaluation.
Topics: Animals; Bleeding Time; Complement Activation; Contrast Media; Dogs; Erythrocytes; Hemolysis; Histam | 1994 |
Evaluation of cervical diskography in pain origin and provocation.
Topics: Adult; Aged; Atrophy; Cervical Vertebrae; Contrast Media; Epidural Space; Female; Humans; Interverte | 1993 |
Local reactions after injection of iodinated contrast material: detection, management, and outcome.
Topics: Blister; Catheterization; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Equipment Design; Extr | 1997 |
Mechanism of pain induced by radiocontrast media.
Topics: Animals; Bradykinin; Contrast Media; Dogs; Female; Iohexol; Iothalamic Acid; Male; Pain; Ruthenium R | 1992 |
Iohexol cervical myelography in adult outpatients.
Topics: Ambulatory Care; Cervical Vertebrae; Evaluation Studies as Topic; Female; Headache; Humans; Incidenc | 1991 |
Premedication and short term complications in iohexol discography.
Topics: Adult; Back Pain; Diazepam; Female; Glycopyrrolate; Headache; Humans; Injections, Spinal; Interverte | 1991 |
Celiac plexus blockade for a 3-year-old boy with hepatoblastoma and refractory pain.
Topics: Bupivacaine; Carcinoma, Hepatocellular; Celiac Plexus; Child, Preschool; Ethanol; Humans; Iohexol; L | 1990 |
Outpatient myelography: an acceptable and cost-effective technique.
Topics: Adult; Aged; Back Pain; Female; Headache; Humans; Iohexol; Male; Middle Aged; Myelography; Nausea; O | 1989 |
Current contrast media and ioxilan. Comparative evaluation of vascular pain by aversion conditioning.
Topics: Animals; Conditioning, Psychological; Contrast Media; Female; Iohexol; Iopamidol; Osmolar Concentrat | 1988 |
[Experimental and clinical studies of non-ionic isoosmolality contrast medium (iohexol 140)--II. IADSA in clinical practice].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiography; Child; Contrast Media; Drug Evaluation; Hem | 1986 |
Lumbar myelography with Omnipaque (iohexol).
Topics: Electroencephalography; Headache; Humans; Iohexol; Lumbar Vertebrae; Myelography; Pain | 1986 |