Page last updated: 2024-10-29

iohexol and Liver Cirrhosis

iohexol has been researched along with Liver Cirrhosis in 25 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"To define the percentage of small (≤2 cm) hepatocellular carcinoma (HCC) nodules showing the diagnostic enhancement pattern at CEUS, computed tomography (CT), and gadobenate dimeglumine (Gd-BOPTA)-enhanced magnetic resonance (MR) imaging."3.79Evidence of diagnostic enhancement pattern in hepatocellular carcinoma nodules ≤2 cm according to the AASLD/EASL revised criteria. ( Angileri, R; Cabibbo, B; Cova, MA; De Paoli, L; Pizzolato, R; Quaia, E, 2013)
"CT portography was performed in 118 cirrhosis patients with body mass index (BMI) less than 25 kg/m under 2 protocols: Protocol A, tube voltage of 90 kVp/395 mAs and contrast agent dosage of 1."2.87Computed tomography portography of patients with cirrhosis with normal body mass index: Comparison between low-tube-voltage CT with low contrast agent dose and conventional CT. ( Fan, J; He, J; Li, W; Liu, S; Sheng, H; Shi, H; Sun, H, 2018)
"Purpose To stage liver fibrosis by using 5-minute delayed DECT and compare findings with those of transient elastography (TE), shear-wave elastography (SWE), and histologic examination."1.62Noninvasive Staging of Liver Fibrosis Using 5-Minute Delayed Dual-Energy CT: Comparison with US Elastography and Correlation with Histologic Findings. ( Das, P; Kalaivani, M; Madhusudhan, KS; Marri, UK; Srivastava, DN, 2021)
"Owing to nonspecific clinical symptoms, Wilson disease (WD) diagnosis is often missed or delayed; hence, many patients reach end-stage liver disease."1.56Assessment of the Hallmarks of Wilson Disease in CT Scan Imaging. ( Haseli, S; Iranpour, P; Jafari, SH; Kaffashan, S; Saeedi-Moghadam, M; Zeinali-Rafsanjani, B, 2020)
"Endoscopy is recommended to screen for esophageal varices in patients with cirrhosis."1.40Esophageal varices on computed tomography and subsequent variceal hemorrhage. ( Ali, M; Aslam, R; Inadomi, JM; Monto, A; Somsouk, M; To'o, K; Vittinghoff, E; Yee, J; Yeh, BM, 2014)
"In patients with liver cirrhosis a urine protein:creatinine ratio >30 predicts AKI."1.39Predicting the development of acute kidney injury in liver cirrhosis--an analysis of glomerular filtration rate, proteinuria and kidney injury biomarkers. ( Auzinger, G; Bernal, W; Bruce, M; Dew, T; Heneghan, MA; McPhail, MJ; Moore, K; Musto, R; O'Grady, J; Ostermann, M; Sherwood, R; Slack, AJ; Wendon, JA, 2013)
"Most patients with HCC have coexisting liver cirrhosis (LC) at the time of diagnosis."1.37Incidence and risk factors for radiocontrast-induced nephropathy in patients with hepatocellular carcinoma undergoing transcatheter arterial chemoembolization. ( Bae, EJ; Chang, SH; Cho, HS; Kang, Y; Kim, HJ; Park, DJ; Seo, JW, 2011)
"In the rabbits with liver fibrosis, the mean transit time of the high-molecular-mass agent was shorter than that of the low-molecular-mass agent (10."1.31Dynamic computed tomography with low- and high-molecular-mass contrast agents to assess microvascular permeability modifications in a model of liver fibrosis. ( Annet, L; Corot, C; Dechambre, S; Horsmans, Y; Materne, R; Sempoux, C; Smith, AM; Van Beers, BE, 2002)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.00)18.2507
2000's3 (12.00)29.6817
2010's18 (72.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Jafari, SH1
Haseli, S1
Kaffashan, S1
Saeedi-Moghadam, M1
Iranpour, P1
Zeinali-Rafsanjani, B1
Gerova, VA1
Svinarov, DA1
Nakov, RV1
Stoynov, SG1
Tankova, LT1
Nakov, VN1
Marri, UK1
Das, P1
Kalaivani, M1
Srivastava, DN1
Madhusudhan, KS1
Jia, GS1
Feng, GL1
Li, JP1
Xu, HL1
Wang, H1
Cheng, YP1
Yan, LL1
Jiang, HJ1
Liu, S1
Sheng, H1
Shi, H1
Li, W1
Fan, J1
He, J1
Sun, H1
Slack, AJ1
McPhail, MJ1
Ostermann, M1
Bruce, M1
Sherwood, R1
Musto, R1
Dew, T1
Auzinger, G1
Bernal, W1
O'Grady, J1
Heneghan, MA1
Moore, K2
Wendon, JA1
Slack, A1
Tredger, M1
Brown, N1
Corcoran, B1
Zhao, LQ1
He, W1
Yan, B1
Wang, HY1
Wang, J1
Sauter, AW1
Spira, D1
Schulze, M1
Horger, MS1
Quaia, E1
De Paoli, L1
Angileri, R1
Pizzolato, R1
Cabibbo, B1
Cova, MA1
Francoz, C2
Nadim, MK1
Baron, A1
Prié, D2
Antoine, C1
Belghiti, J2
Valla, D2
Moreau, R2
Durand, F2
Zissen, MH1
Wang, ZJ1
Yee, J2
Aslam, R2
Monto, A2
Yeh, BM2
Somsouk, M1
To'o, K1
Ali, M1
Vittinghoff, E1
Inadomi, JM1
Lee, S1
Choi, D1
Jeong, WK1
Kim, YK1
Lim, JH1
Choi, MS1
Park, CK1
Bandula, S1
Punwani, S1
Rosenberg, WM1
Jalan, R1
Hall, AR1
Dhillon, A1
Moon, JC1
Taylor, SA1
Lewin, M1
Gelu-Simeon, M1
Ostos, M1
Boufassa, F1
Sobesky, R1
Teicher, E1
Meyer, L1
Fontaine, H1
Salmon-Céron, D1
Samuel, D1
Seror, O1
Trinchet, JC1
Duclos-Vallée, JC1
Li, R1
Cai, P1
Ma, KS1
Ding, SY1
Guo, DY1
Yan, XC1
Nakai, M1
Sato, M1
Ikoma, A1
Nakata, K1
Sahara, S1
Takasaka, I1
Minamiguchi, H1
Kawai, N1
Sonomura, T1
Kishi, K1
Ronot, M1
Asselah, T1
Paradis, V1
Michoux, N1
Dorvillius, M1
Baron, G1
Marcellin, P1
Van Beers, BE3
Vilgrain, V1
Abdelrazek, W1
Mandot, A1
Cho, HS1
Seo, JW1
Kang, Y1
Bae, EJ1
Kim, HJ1
Chang, SH1
Park, DJ1
Materne, R2
Annet, L1
Dechambre, S1
Sempoux, C1
Smith, AM2
Corot, C1
Horsmans, Y2
Hayashi, M1
Matsui, O1
Ueda, K1
Kawamori, Y1
Gabata, T1
Kadoya, M1
Lee, HM1
Lu, DS1
Krasny, RM1
Busuttil, R1
Kadell, B1
Lucas, J1
Leconte, I1
Jamart, J1

Trials

1 trial available for iohexol and Liver Cirrhosis

ArticleYear
Computed tomography portography of patients with cirrhosis with normal body mass index: Comparison between low-tube-voltage CT with low contrast agent dose and conventional CT.
    Medicine, 2018, Volume: 97, Issue:48

    Topics: Adult; Aged; Body Mass Index; Contrast Media; Dose-Response Relationship, Drug; Female; Humans; Iohe

2018

Other Studies

24 other studies available for iohexol and Liver Cirrhosis

ArticleYear
Assessment of the Hallmarks of Wilson Disease in CT Scan Imaging.
    Journal of medical imaging and radiation sciences, 2020, Volume: 51, Issue:1

    Topics: Adolescent; Adult; Child; Contrast Media; Female; Hepatolenticular Degeneration; Humans; Iohexol; Li

2020
Intestinal barrier dysfunction in liver cirrhosis assessed by iohexol test.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:1

    Topics: Adult; Aged; Female; Healthy Volunteers; Humans; Intestinal Diseases; Iohexol; Liver Cirrhosis; Male

2020
Noninvasive Staging of Liver Fibrosis Using 5-Minute Delayed Dual-Energy CT: Comparison with US Elastography and Correlation with Histologic Findings.
    Radiology, 2021, Volume: 298, Issue:3

    Topics: Adult; Biopsy; Contrast Media; Elasticity Imaging Techniques; Female; Humans; Iohexol; Liver Cirrhos

2021
Using receiver operating characteristic curves to evaluate the diagnostic value of the combination of multislice spiral CT and alpha-fetoprotein levels for small hepatocellular carcinoma in cirrhotic patients.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2017, Volume: 16, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Carcinoma, Hepatocellular; Case-Control Studies; C

2017
Predicting the development of acute kidney injury in liver cirrhosis--an analysis of glomerular filtration rate, proteinuria and kidney injury biomarkers.
    Alimentary pharmacology & therapeutics, 2013, Volume: 37, Issue:10

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Adult; Aged; Biomarkers; Cohort Studies; Contrast Media;

2013
Application of an isocratic methanol-based HPLC method for the determination of iohexol concentrations and glomerular filtration rate in patients with cirrhosis.
    Annals of clinical biochemistry, 2014, Volume: 51, Issue:Pt 1

    Topics: Adult; Aged; Ascitic Fluid; Chromatography, High Pressure Liquid; Chromium Radioisotopes; Creatinine

2014
The evaluation of haemodynamics in cirrhotic patients with spectral CT.
    The British journal of radiology, 2013, Volume: 86, Issue:1028

    Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Female; Hemodynamics; Humans; Hypertension, Portal;

2013
Explanations for the heterogeneity of splenic enhancement derived from blood flow kinetic measurements using dynamic contrast-enhanced CT (DCE-CT).
    Acta radiologica (Stockholm, Sweden : 1987), 2014, Volume: 55, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Blood Volume; Contrast Media; Female; Humans; I

2014
Evidence of diagnostic enhancement pattern in hepatocellular carcinoma nodules ≤2 cm according to the AASLD/EASL revised criteria.
    Abdominal imaging, 2013, Volume: 38, Issue:6

    Topics: Aged; Biopsy; Carcinoma, Hepatocellular; Contrast Media; Diagnosis, Differential; Female; Humans; Im

2013
Glomerular filtration rate equations for liver-kidney transplantation in patients with cirrhosis: validation of current recommendations.
    Hepatology (Baltimore, Md.), 2014, Volume: 59, Issue:4

    Topics: Adult; Aged; Comorbidity; Disease Management; Female; Glomerular Filtration Rate; Humans; Iohexol; K

2014
Contrast-enhanced CT quantification of the hepatic fractional extracellular space: correlation with diffuse liver disease severity.
    AJR. American journal of roentgenology, 2013, Volume: 201, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Contrast Media; Extracellular Space; Female; H

2013
Esophageal varices on computed tomography and subsequent variceal hemorrhage.
    Abdominal imaging, 2014, Volume: 39, Issue:2

    Topics: Case-Control Studies; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Esophageal and Gastric Var

2014
Frequency, CT findings, and fate of multiple infarcted regenerative nodules in liver cirrhosis after variceal bleeding or septic shock.
    Abdominal imaging, 2015, Volume: 40, Issue:4

    Topics: Aged; Comorbidity; Contrast Media; Esophageal and Gastric Varices; Female; Follow-Up Studies; Gastro

2015
Equilibrium contrast-enhanced CT imaging to evaluate hepatic fibrosis: initial validation by comparison with histopathologic sampling.
    Radiology, 2015, Volume: 275, Issue:1

    Topics: Adult; Aged; Biopsy; Contrast Media; Female; Humans; Iohexol; Liver Cirrhosis; Male; Middle Aged; Pr

2015
Imaging Features and Prognosis of Hepatocellular Carcinoma in Patients with Cirrhosis Who Are Coinfected with Human Immunodeficiency Virus and Hepatitis C Virus.
    Radiology, 2015, Volume: 277, Issue:2

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Coinfection; Contrast Media; Diagnostic Imaging; Female; Fra

2015
Dynamic enhancement patterns of intrahepatic cholangiocarcinoma in cirrhosis on contrast-enhanced computed tomography: risk of misdiagnosis as hepatocellular carcinoma.
    Scientific reports, 2016, 05-26, Volume: 6

    Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cholangiocarcinoma; Contrast Media; Diagn

2016
Triple-phase computed tomography during arterial portography with bolus tracking for hepatic tumors.
    Japanese journal of radiology, 2010, Volume: 28, Issue:2

    Topics: Aged; Carcinoma, Hepatocellular; Contrast Media; Digestive System Neoplasms; Female; Hepatitis C; Hu

2010
Liver fibrosis in chronic hepatitis C virus infection: differentiating minimal from intermediate fibrosis with perfusion CT.
    Radiology, 2010, Volume: 256, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Biopsy; Contrast Media; Female; Hepatitis C, Chronic; Humans; Iohexo

2010
Inaccuracies of creatinine and creatinine-based equations in candidates for liver transplantation with low creatinine: impact on the model for end-stage liver disease score.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2010, Volume: 16, Issue:10

    Topics: Adult; Aged; Biomarkers; Contrast Media; Creatinine; Female; France; Glomerular Filtration Rate; Hea

2010
Incidence and risk factors for radiocontrast-induced nephropathy in patients with hepatocellular carcinoma undergoing transcatheter arterial chemoembolization.
    Clinical and experimental nephrology, 2011, Volume: 15, Issue:5

    Topics: Acute Kidney Injury; Aged; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Contrast Media

2011
Dynamic computed tomography with low- and high-molecular-mass contrast agents to assess microvascular permeability modifications in a model of liver fibrosis.
    Clinical science (London, England : 1979), 2002, Volume: 103, Issue:2

    Topics: Animals; Capillary Permeability; Contrast Media; Iohexol; Liver; Liver Cirrhosis; Male; Molecular We

2002
Progression to hypervascular hepatocellular carcinoma: correlation with intranodular blood supply evaluated with CT during intraarterial injection of contrast material.
    Radiology, 2002, Volume: 225, Issue:1

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Contrast Media; Disease Progression; Female; Hepatic Artery;

2002
Hepatic lesion characterization in cirrhosis: significance of arterial hypervascularity on dual-phase helical CT.
    AJR. American journal of roentgenology, 1997, Volume: 169, Issue:1

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Contrast Media; Female; Humans; Iohexol; Liver; Liver Cirrho

1997
Hepatic perfusion parameters in chronic liver disease: dynamic CT measurements correlated with disease severity.
    AJR. American journal of roentgenology, 2001, Volume: 176, Issue:3

    Topics: Case-Control Studies; Chronic Disease; Contrast Media; Female; Humans; Iohexol; Liver Circulation; L

2001