iohexol and Kidney Diseases studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Research Excerpts

Excerpt	Relevance	Reference
"The aim of this clinical trial is to compare iodixanol with iohexol for the incidence of contrast-induced nephropathy in patients with chronic heart failure with reduced ejection fraction who are currently undergoing coronary angiography or angioplasty."	9.24	Comparison of the nephrotoxic effects of iodixanol versus iohexol in patients with chronic heart failure undergoing coronary angiography or angioplasty. ( Ge, Z; Li, Y; Shi, P; Song, M; Song, T; Sun, M, 2017)
"In order to compare the effects of iopromide and isoxazole on postoperative contrast-induced nephropathy in patients with renal insufficiency, the paper searches for randomized controlled trials and retrospective cohort studies comparing the effects of iopromide and iodixanol on renal function in patients with renal insufficiency after surgery."	9.22	Iopromide and Iodixanol in the Development of Postoperative Contrast Nephropathy in Patients with Renal Insufficiency: A Meta-Analysis. ( Duan, Z; Feng, Y; Hu, W; Li, P; Qiu, G; Wang, L; Wang, M; Xu, C; Zhou, H, 2022)
"This study aims to investigate the preventive effect of oral nicorandil on contrast-induced nephropathy (CIN) in patients with renal insufficiency undergoing elective cardiac catheterization."	9.22	Preventive effect of oral nicorandil on contrast-induced nephropathy in patients with renal insufficiency undergoing elective cardiac catheterization. ( Cai, J; Du, R; Fan, Y; Li, Y; Lin, S; Lv, J; Shi, Y; Wang, X; Wei, Q; Yao, L; Zhang, Y; Zhou, B, 2016)
" The objective of our meta-analysis was to compare the clinical safety of iso-osmolar contrast medium iodixanol to low-osmolar contrast medium iopromide in patients with renal insufficiency undergoing coronary angiography with or without percutaneous coronary intervention (PCI)."	8.98	Iodixanol versus iopromide in patients with renal insufficiency undergoing coronary angiography with or without PCI. ( Chen, M; Jiang, Y; Rui, Q; Yang, H; Zhang, J; Zhang, N; Zhou, Y, 2018)
"In children and young adults with haemato-oncological disease and infection, renal function is best described by iohexol clearance from three-compartment pharmacokinetic model, while eGFR equations and single- and two-point mGFR formulas overestimate iGFR."	8.12	Glomerular filtration rate in children and young adults with haemato-oncological disease and infection is best described by three-compartment iohexol model. ( Karu, M; Kõrgvee, LT; Lass, J; Lutsar, I; Noortoots, A; Saks, K; Soeorg, H, 2022)
"To compare the performance of iohexol plasma clearance and creatinine-based renal function estimating equations in monitoring longitudinal renal function changes in chronic heart failure (CHF) patients, and to assess the effects of body composition on the equation performance."	7.81	Iohexol clearance is superior to creatinine-based renal function estimating equations in detecting short-term renal function decline in chronic heart failure. ( Anker, SD; Cvan Trobec, K; Kerec Kos, M; Lainscak, M; Macdougall, IC; Ponikowski, P; von Haehling, S, 2015)
"The aim of this clinical trial is to compare iodixanol with iohexol for the incidence of contrast-induced nephropathy in patients with chronic heart failure with reduced ejection fraction who are currently undergoing coronary angiography or angioplasty."	5.24	Comparison of the nephrotoxic effects of iodixanol versus iohexol in patients with chronic heart failure undergoing coronary angiography or angioplasty. ( Ge, Z; Li, Y; Shi, P; Song, M; Song, T; Sun, M, 2017)
"In order to compare the effects of iopromide and isoxazole on postoperative contrast-induced nephropathy in patients with renal insufficiency, the paper searches for randomized controlled trials and retrospective cohort studies comparing the effects of iopromide and iodixanol on renal function in patients with renal insufficiency after surgery."	5.22	Iopromide and Iodixanol in the Development of Postoperative Contrast Nephropathy in Patients with Renal Insufficiency: A Meta-Analysis. ( Duan, Z; Feng, Y; Hu, W; Li, P; Qiu, G; Wang, L; Wang, M; Xu, C; Zhou, H, 2022)
"This study aims to investigate the preventive effect of oral nicorandil on contrast-induced nephropathy (CIN) in patients with renal insufficiency undergoing elective cardiac catheterization."	5.22	Preventive effect of oral nicorandil on contrast-induced nephropathy in patients with renal insufficiency undergoing elective cardiac catheterization. ( Cai, J; Du, R; Fan, Y; Li, Y; Lin, S; Lv, J; Shi, Y; Wang, X; Wei, Q; Yao, L; Zhang, Y; Zhou, B, 2016)
" In 562 evaluable patients (of 592 recruited), the contrast volume, presence of diabetes mellitus, mean baseline SCr and estimated glomerular filtration rate (eGFR) were comparable between the iopromide- and iodixanol-treated groups."	5.16	Renal tolerability of iopromide and iodixanol in 562 renally impaired patients undergoing cardiac catheterisation: the DIRECT study. ( Chen, Y; Fu, G; Gao, C; Gao, W; He, B; He, Q; Hu, S; Liu, H; Liu, S; Liu, Y; Qi, X; Qiu, C; Su, X; Wang, J; Wang, L; Wang, M; Yang, P; Zhao, R; Zheng, X; Zheng, Y; Zhou, S, 2012)
" The objective of our meta-analysis was to compare the clinical safety of iso-osmolar contrast medium iodixanol to low-osmolar contrast medium iopromide in patients with renal insufficiency undergoing coronary angiography with or without percutaneous coronary intervention (PCI)."	4.98	Iodixanol versus iopromide in patients with renal insufficiency undergoing coronary angiography with or without PCI. ( Chen, M; Jiang, Y; Rui, Q; Yang, H; Zhang, J; Zhang, N; Zhou, Y, 2018)
"In children and young adults with haemato-oncological disease and infection, renal function is best described by iohexol clearance from three-compartment pharmacokinetic model, while eGFR equations and single- and two-point mGFR formulas overestimate iGFR."	4.12	Glomerular filtration rate in children and young adults with haemato-oncological disease and infection is best described by three-compartment iohexol model. ( Karu, M; Kõrgvee, LT; Lass, J; Lutsar, I; Noortoots, A; Saks, K; Soeorg, H, 2022)
"To compare the performance of iohexol plasma clearance and creatinine-based renal function estimating equations in monitoring longitudinal renal function changes in chronic heart failure (CHF) patients, and to assess the effects of body composition on the equation performance."	3.81	Iohexol clearance is superior to creatinine-based renal function estimating equations in detecting short-term renal function decline in chronic heart failure. ( Anker, SD; Cvan Trobec, K; Kerec Kos, M; Lainscak, M; Macdougall, IC; Ponikowski, P; von Haehling, S, 2015)
"The study investigated plasma clearance of exogenous creatinine (PECCT), exo-iohexol (PexICT) and endo-iohexol (PenICT) in six healthy cats, four cats with chronic kidney disease (CKD) and six hyperthyroid (HT) cats to assess potential differences in glomerular filtration rate (GFR) measurement over a wide range of GFR values."	3.75	Comparison of plasma clearance of exogenous creatinine, exo-iohexol, and endo-iohexol over a range of glomerular filtration rates expected in cats. ( Biourge, V; Croubels, S; Daminet, S; Lefebvre, HP; Paepe, D; van Hoek, IM, 2009)
"Iodixanol was cost-effective compared with iohexol, with both lower costs and better effects related to fewer adverse drug reactions."	2.71	Cost-effectiveness of iodixanol in patients at high risk of contrast-induced nephropathy. ( Aspelin, P; Aubry, P; Fransson, SG; Lundkvist, J; Strasser, R; Willenbrock, R, 2005)
" The main outcome measures were diagnostic utility, incidence of alternative diagnoses, requirement for further imaging, length of hospital stay, urological intervention rates, radiation dosage and costs."	2.71	Renal colic: a prospective evaluation of non-enhanced spiral CT versus intravenous pyelography. ( Anderson, JE; Arnold-Reed, DE; Bulsara, MK; Kuan, M; Mander, J; Mendelson, RM; Sweetman, G; Wedderburn, AW, 2003)
"Iohexol was given as a single iv dose, and blood samples were drawn up to 600 min after the administration."	2.68	Plasma clearance of nonradioactive iohexol as a measure of glomerular filtration rate. ( Amuchastegui, CS; Daina, E; Gaspari, F; Guerini, E; Mosconi, L; Perico, N; Remuzzi, G; Ruggenenti, P, 1995)
"Nephrotoxicity of radio-opaque contrast media (CM) is generally believed to involve toxic injury of proximal tubular cells."	2.66	Nephrotoxicity of high- and low-osmolality contrast media. ( Avila, A; Dennis, B; Finnie, KJ; Jevnikar, AM; Linton, AL; Plummer, DT, 1988)
"To determine whether there are significant differences among low-osmolality CM (LOCM) in the incidence of contrast-induced nephropathy (CIN), we reviewed published studies of CIN in renally impaired patients and conducted statistical data mining using databases of adverse events maintained by the U."	2.43	Contrast media and nephropathy: findings from systematic analysis and Food and Drug Administration reports of adverse effects. ( Dumouchel, W; Solomon, R, 2006)
" Assuming a varying number of random effects, we re-estimated previously developed population pharmacokinetic two- and three-compartment models in a model development group comprising 546 patients with iohexol concentration data up to 300 min post injection."	1.62	Advancement of pharmacokinetic models of iohexol in patients aged 70 years or older with impaired kidney function. ( Ebert, N; Fuhr, U; Lösment, A; Martus, P; Schaeffner, E; Taubert, M; van der Giet, M, 2021)
"The iohexol measurements were also compared with blood samples collected simultaneously on filter paper."	1.42	Estimating GFR in adult patients with hematopoietic cell transplant: comparison of estimating equations with an iohexol reference standard. ( Gooley, T; Hingorani, S; Pao, E; Schoch, G; Schwartz, GJ, 2015)
"7 mL/min/kg) and a significantly lower mean volume of distribution at steady state (250 ± 37 mL/kg vs 539 ± 73 mL/kg), mean residence time (80 ± 31 minutes vs 195 ± 73 minutes), and mean elimination half-life (74 ± 20 minutes vs 173 ± 53 minutes)."	1.38	Comparison of pharmacokinetic variables for creatinine and iohexol in dogs with various degrees of renal function. ( Balouka, D; Biourge, V; Collignon, CM; Concordet, D; Craig, AJ; Eliassen, KA; Faucher, MR; Harran, NX; Heiene, R; Lefebvre, HP; Queau, Y; Reynolds, BS; Risøen, U, 2012)
"Iodine concentration was calculated and compared with known iodine concentration."	1.37	Iodine quantification with dual-energy CT: phantom study and preliminary experience with renal masses. ( Chandarana, H; Cohen, BA; Kim, D; Leidecker, C; Macari, M; Megibow, AJ; Srinivasan, R, 2011)
"Proteinuria was in the nephrotic range in 44 and the BMI exceeded the 95th percentile in 57 patients of this cohort."	1.36	Dyslipidemia in children with chronic kidney disease. ( Flynn, JT; Furth, SL; Goebel, J; Kupferman, JC; Mitsnefes, MM; Pierce, CB; Saland, JM; Warady, BA, 2010)
" This prospective study determined the incidence of CIN for two nonionic contrast media (CM), iopromide and iohexol, among 80 patients younger than 18 years and compared the rates for this complication in relation to the type and dosage of CM and the presence of cyanosis."	1.36	Risk of nephropathy after consumption of nonionic contrast media by children undergoing cardiac angiography: a prospective study. ( Abtahi, S; Ajami, G; Amoozgar, H; Basiratnia, M; Borzouee, M; Cheriki, S; Derakhshan, A; Mohamadi, M; Soltani, M, 2010)
" LOCM was less toxic to rat kidneys than HOCM."	1.35	The protective role of telmisartan against nephrotoxicity induced by X-ray contrast media in rat model. ( Duan, SB; Liu, FY; Peng, YM; Wang, P; Wang, YH; Xu, XQ; Zou, Q, 2009)
"Lung cancer is treatable with platinum-based cytostatic drugs, which can be nephrotoxic."	1.35	[Delay in implementation of international guidelines for computed tomographies with iodinated contrast media]. ( Holländer, C, 2009)
"Proteinuria is associated with chronic kidney disease (CKD), and heavy proteinuria predicts a rapid decline in kidney function."	1.35	Association of proteinuria with race, cause of chronic kidney disease, and glomerular filtration rate in the chronic kidney disease in children study. ( Benador, NM; Cole, SR; Furth, SL; Kaskel, F; Mak, RH; Pierce, CB; Schwartz, GJ; Warady, BA; Wong, CS, 2009)
"Insulin resistance was estimated by quantitative insulin-sensitivity check index (QUICKI) and homeostasis model assessment for insulin resistance (HOMA-IR) and body composition by dual-energy X-ray absorptiometry."	1.33	Elevated resistin levels in chronic kidney disease are associated with decreased glomerular filtration rate and inflammation, but not with insulin resistance. ( Alvestrand, A; Axelsson, J; Bárány, P; Bergsten, A; Heimbürger, O; Lindholm, B; Lönnqvist, F; Nordfors, L; Qureshi, AR; Stenvinkel, P, 2006)
"Iohexol (5 ml) was administered intravenously and blood samples were obtained at 10, 20, 30, 60, 120, 240, 300, and 360 min after injection (N=29) and assayed by high performance liquid chromatography."	1.33	Glomerular filtration rate via plasma iohexol disappearance: pilot study for chronic kidney disease in children. ( Cole, SR; Furth, S; Muñoz, A; Schwartz, GJ; Warady, B, 2006)
"Iohexol molecules were less nephrotoxic than the Gd-CM molecules and contain three-times the number of attenuating atoms per molecule."	1.33	Gadolinium contrast media are more nephrotoxic than iodine media. The importance of osmolality in direct renal artery injections. ( Almén, T; Björk, J; Chai, CM; Elmståhl, B; Golman, K; Leander, P; Nyman, U, 2006)
"Hypertension was present in 38% of the donors but the age-adjusted prevalence of hypertension among donors was not higher than in the general population."	1.31	No evidence of accelerated loss of kidney function in living kidney donors: results from a cross-sectional follow-up. ( Brink, B; Dunér, F; Elinder, CG; Fehrman-Ekholm, I; Tydén, G, 2001)
"Two renal cell carcinomas were overlooked by the interpreters of the helical scans in group 1."	1.30	Dual-phase helical CT of the kidney: value of the corticomedullary and nephrographic phase for evaluation of renal lesions and preoperative staging of renal cell carcinoma. ( Fischer, U; Grabbe, E; Kopka, L; Ringert, RH; Schmidt, C; Zoeller, G, 1997)
"Reflux nephropathy i."	1.30	15-year follow-up of reflux nephropathy by imaging. ( Dillon, MJ; Goonasekera, CD; Gordon, I, 1998)
"Eighteen renal cell carcinomas and 8 other tumours were found; 78 kidneys had cysts, 12 polycystic kidneys and 10 fibrotic kidneys were detected, 20 kidneys showed other findings."	1.30	Renal masses--evaluation by amplitude coded colour Doppler sonography and multiphasic contrast-enhanced CT. ( Dörfler, O; Kugler, C; Preidler, K; Riccabona, M; Schreyer, HH; Szolar, D; Uggowitzer, M, 1999)
"In glycerol treated rats, a peak in serum creatinine was seen on day 2 which returned to normal level by day 4."	1.28	Contrast media-induced lipid peroxidation in the rat kidney. ( Moncada, R; Parvez, Z; Rahman, MA, 1989)

Research

Studies (187)

Authors

Clinical Trials (12)

Trial Overview

Trial Outcomes

Number of Participants Who Develop Delayed Cerebral Vasospasm

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (2.67)	18.7374
1990's	32 (17.11)	18.2507
2000's	72 (38.50)	29.6817
2010's	70 (37.43)	24.3611
2020's	8 (4.28)	2.80

Authors	Studies
Soeorg, H	1
Noortoots, A	1
Karu, M	1
Saks, K	1
Lass, J	1
Lutsar, I	1
Kõrgvee, LT	1
Fang, D	1
Wang, Y	2
Zhang, Z	1
Yang, D	1
Gu, D	2
He, B	2
Zhang, X	1
He, D	2
Wang, H	1
Jose, PA	1
Han, Y	2
Zeng, C	2
Taubert, M	1
Schaeffner, E	1
Martus, P	1
van der Giet, M	1
Fuhr, U	1
Lösment, A	1
Ebert, N	1
Fujino, S	1
Sun, J	1
Nakayama, S	1
Horikoshi, Y	1
Kinugasa, Y	1
Ishida, M	1
Sakai, C	1
Ike, T	1
Doi, S	1
Masaki, T	1
Tashiro, S	1
Feng, Y	1
Qiu, G	1
Xu, C	1
Duan, Z	1
Wang, M	2
Wang, L	2
Hu, W	1
Li, P	1
Zhou, H	1
Ognissanti, D	1
Andresen Bergström, M	1
Theodorsson, E	1
Larsson, A	2
Nordin, G	1
Hammarsten, O	1
Hajji, M	1
Jebali, H	1
Chaabouni, E	1
Mzoughi, K	1
Zairi, I	1
Kraiem, S	1
Raies, L	1
Hamida, FB	1
Fatma, LB	1
Zouaghi, MK	1
Abdallah, TB	1
Chardon, L	1
Dubourg, L	1
Barin-Le Guellec, C	1
Guinard, F	1
Hannedouche, T	1
Halimi, JM	1
Mariat, C	1
Gasthuys, E	1
Montesinos, A	1
Caekebeke, N	1
Devreese, M	1
De Baere, S	1
Ardiaca, M	1
Paepe, D	2
Croubels, S	2
Antonissen, G	1
Shi, Y	2
Gong, Z	1
Xia, T	1
Ren, H	1
Yang, J	2
Sundin, PO	1
Sjöström, P	1
Jones, I	1
Olsson, LA	1
Udumyan, R	1
Grubb, A	4
Lindström, V	2
Montgomery, S	1
Song, T	1
Song, M	1
Ge, Z	1
Li, Y	2
Shi, P	1
Sun, M	1
Lee, D	1
Cho, ES	1
Kim, JH	1
Kim, YP	1
Lee, HK	1
Yu, JS	1
Chung, JJ	1
Pandya, VK	1
Sutariya, HC	1
Gandhi, SP	1
Khemchandani, SI	1
Patel, HV	1
Shah, MK	1
Tsamouri, MM	1
Rapti, M	1
Kouka, P	1
Nepka, C	1
Tsarouhas, K	1
Soumelidis, A	1
Koukoulis, G	1
Tsatsakis, A	1
Kouretas, D	1
Tsitsimpikou, C	1
Terrenato, I	1
Sperati, F	1
Musicco, F	1
Pozzi, AF	1
di Turi, A	1
Caterino, M	1
de Lutio di Castelguidone, E	1
Setola, SV	1
Bellomi, M	1
Neumaier, CE	1
Conti, L	1
Cigliana, G	1
Merola, R	1
Antenucci, A	1
Orlandi, G	1
Giordano, A	1
Barba, M	1
Canitano, S	1
Luis-Lima, S	1
Gaspari, F	3
Negrín-Mena, N	1
Carrara, F	1
Díaz-Martín, L	1
Jiménez-Sosa, A	1
González-Rinne, F	1
Torres, A	1
Porrini, E	1
Zhang, J	2
Jiang, Y	1
Rui, Q	1
Chen, M	1
Zhang, N	1
Yang, H	1
Zhou, Y	1
Yang, SF	1
Chou, RH	1
Li, SY	1
Huang, SS	1
Huang, PH	1
Krishna, S	1
Sadoughi, N	1
McInnes, MDF	1
Chatelain, R	1
MacDonald, DB	1
Schieda, N	1
Kim, JE	1
Bae, SY	1
Ahn, SY	1
Kwon, YJ	1
Ko, GJ	1
Zhao, HW	1
Zhang, XJ	1
Chen, BJ	1
Yu, GN	1
Hou, AJ	1
Luan, B	1
Becker, J	1
Babb, J	1
Serrano, M	1
Chousterman, BG	1
Bouadma, L	1
Moutereau, S	1
Loric, S	1
Alvarez-Gonzalez, A	1
Mekontso-Dessap, A	1
Laissy, JP	1
Rahmouni, A	1
Katsahian, S	1
Brochard, L	1
Schortgen, F	1
Murakami, R	1
Kumita, S	1
Hayashi, H	1
Sugizaki, K	1
Okazaki, E	1
Kiriyama, T	1
Hakozaki, K	1
Tani, H	1
Miki, I	1
Takeda, M	1
Nakamura, A	1
Miura, S	1
Sugihara, M	1
Miyase, Y	1
Norimatsu, K	1
Shiga, Y	1
Nishikawa, H	1
Saku, K	1
Cicin, I	1
Erdogan, B	1
Gulsen, E	1
Uzunoglu, S	1
Sut, N	1
Turkmen, E	1
Kodaz, H	1
Ustundag, S	1
Kama, A	1
Yılmaz, S	1
Yaka, E	1
Dervişoğlu, E	1
Doğan, NÖ	1
Erimşah, E	1
Pekdemir, M	1
Prasad, V	1
Gandhi, D	1
Stokum, C	1
Miller, T	1
Jindal, G	1
Finch, N	1
Yeganehkhah, MR	1
Iranirad, L	1
Dorri, F	1
Pazoki, S	1
Akbari, H	1
Miryounesi, M	1
Vahedian, M	1
Nazeri, A	1
Hosseinzadeh, F	1
Vafaeimanesh, J	1
Acikel, S	1
Akdemir, R	1
Kilic, H	1
Cagirci, G	1
Dogan, M	1
Yesilay, AB	1
Yeter, E	1
Osman, Ö	1
Ayee Deniz, O	1
Abdülkadir, E	1
Cihat, Ş	1
Hüsnü Oğuz, S	1
Avse Banu, Ç	1
Hingorani, S	1
Pao, E	1
Schoch, G	1
Gooley, T	1
Schwartz, GJ	6
Kunak, CS	1
Ugan, RA	1
Cadirci, E	1
Karakus, E	1
Polat, B	1
Un, H	1
Halici, Z	1
Saritemur, M	1
Atmaca, HT	1
Karaman, A	1
Cvan Trobec, K	1
Kerec Kos, M	1
von Haehling, S	1
Anker, SD	1
Macdougall, IC	1
Ponikowski, P	1
Lainscak, M	1
Fananapazir, G	1
Troppmann, C	1
Corwin, MT	1
Bent, CK	1
Vu, CT	1
Lamba, R	1
Fan, Y	1
Wei, Q	1
Cai, J	1
Zhang, Y	1
Yao, L	1
Wang, X	1
Lin, S	1
Lv, J	1
Zhou, B	1
Du, R	1
Sayarlioglu, H	1
Okuyucu, A	1
Bedir, A	1
Salis, O	1
Yenen, E	1
Bekfilavioglu, G	1
Kaya, C	1
Bakoush, O	1
Rippe, B	1
Billings, FT	1
Chen, SW	1
Kim, M	2
Park, SW	1
Song, JH	1
Wang, S	1
Herman, J	1
D'Agati, V	1
Lee, HT	2
Juergens, CP	1
Winter, JP	1
Nguyen-Do, P	1
Lo, S	1
French, JK	1
Hallani, H	1
Fernandes, C	1
Jepson, N	1
Leung, DY	1
Nie, B	1
Cheng, WJ	1
Li, YF	1
Cao, Z	1
Yang, Q	1
Zhao, YX	1
Guo, YH	1
Zhou, YJ	1
Peters, AM	3
Bird, NJ	3
Halsall, I	1
Peters, C	2
Michell, AR	3
Jost, G	1
Pietsch, H	1
Sommer, J	1
Sandner, P	1
Lengsfeld, P	1
Seidensticker, P	1
Lehr, S	1
Hütter, J	1
Sieber, MA	1
Shakourirad, A	1
Ataeefar, M	1
Jozaghi, S	1
Budhiraja, P	1
Chen, Z	1
Popovtzer, M	1
Bruce, RJ	1
Djamali, A	1
Shinki, K	1
Michel, SJ	1
Fine, JP	1
Pozniak, MA	2
Mahadevia, S	1
Rozenblit, A	1
Milikow, D	1
Marinovich, A	1
Sterner, G	4
Björk, J	3
Carlson, J	1
Nyman, U	5
Wong, CS	1
Pierce, CB	2
Cole, SR	2
Warady, BA	4
Mak, RH	1
Benador, NM	1
Kaskel, F	1
Furth, SL	4
Schaefer, F	1
Cohen, MD	1
Holländer, C	1
Duan, SB	1
Wang, YH	1
Liu, FY	1
Xu, XQ	1
Wang, P	1
Zou, Q	1
Peng, YM	1
Rajani, R	1
Haworth, P	1
Hildick-Smith, D	1
Jabara, R	1
Gadesam, RR	1
Pendyala, LK	1
Knopf, WD	1
Chronos, N	1
Chen, JP	1
Viel, K	1
King, SB	1
Manoukian, SV	1
Reed, M	1
Meier, P	1
Tamhane, UU	1
Welch, KB	1
Moscucci, M	1
Gurm, HS	1
van Hoek, IM	1
Lefebvre, HP	2
Biourge, V	2
Daminet, S	1
Shamkhalova, MSh	1
Zaĭtseva, NV	1
Kurumova, KO	1
Shestakova, MV	1
Deev, AD	1
Matskeplishvili, ST	1
Tugeeva, EF	1
Buziashvili, IuI	1
Abraham, AG	1
Muñoz, A	3
Miyagawa, Y	2
Takemura, N	2
Hirose, H	2
Maple-Brown, LJ	1
Lawton, PD	1
Hughes, JT	1
Sharma, SK	2
Jones, GR	1
Ellis, AG	1
Hoy, W	1
Cass, A	1
Macisaac, RJ	1
Sinha, AK	1
Thomas, MA	1
Piers, LS	1
Ward, LC	1
Drabsch, K	1
Panagiotopoulos, S	1
McDermott, R	1
Warr, K	1
Cherian, S	1
Brown, A	1
Jerums, G	1
O'Dea, K	1
Ajami, G	1
Derakhshan, A	1
Amoozgar, H	1
Mohamadi, M	1
Borzouee, M	1
Basiratnia, M	1
Abtahi, S	1
Cheriki, S	1
Soltani, M	1
Sendeski, M	1
Patzak, A	1
Persson, PB	2
Glass, DM	1
Sochman, J	1
Peregrin, JH	1
Bürgelová, M	1
Kopkan, L	1
Kramer, HJ	1
Cervenka, L	1
Rezai, P	1
Tochetto, S	1
Galizia, M	1
Yaghmai, V	1
Sox, EM	1
Chiotti, R	1
Goldstein, RE	1
Saland, JM	1
Mitsnefes, MM	1
Flynn, JT	1
Goebel, J	1
Kupferman, JC	1
Kim, KS	1
Kim, K	1
Hwang, SS	1
Jo, YH	1
Lee, CC	1
Kim, TY	1
Rhee, JE	1
Suh, GJ	1
Singer, AJ	1
Kim, HD	1
Berg, UB	1
Bäck, R	1
Celsi, G	1
Halling, SE	1
Homberg, I	1
Krmar, RT	1
Monemi, KÅ	1
Oborn, H	1
Herthelius, M	1
Francoz, C	1
Prié, D	1
Abdelrazek, W	1
Moreau, R	1
Mandot, A	1
Belghiti, J	1
Valla, D	1
Durand, F	1
Mager, A	1
Vaknin Assa, H	1
Lev, EI	1
Bental, T	1
Assali, A	1
Kornowski, R	1
Karpishchenko, SN	1
Zheregelia, SN	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Impact of Body Composition Changes and Cachexia on Bisoprolol and Ramipril Pharmacokinetics and Renal Function Estimation in Patients With Chronic Heart Failure[NCT01829880]		60 participants (Anticipated)	Observational	2011-10-31	Recruiting
C-arm Cone Beam CTA and CTP With Acetazolamide Challenge in Aneurysmal Subarachnoid Hemorrhage: Evaluating Predictability for Early Ischemia in Cerebral Vasospasm[NCT03377049]	Phase 4	11 participants (Actual)	Interventional	2019-07-28	Completed
Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)[NCT00327860]		1,100 participants (Actual)	Observational	2003-10-31	Active, not recruiting
Prediction of Excretion and Toxicity of High Dose Methotrexate in Children and Adolescents With Acute Lymphoblastic Leukemia and Lymphoma[NCT02133599]		23 participants (Actual)	Interventional	2014-07-24	Completed
Chinese People's Liberation Army General Hospital[NCT02718521]		400 participants (Anticipated)	Interventional	2016-03-31	Active, not recruiting
Chinese People's Liberation Army General Hospital[NCT02405377]		264 participants (Actual)	Interventional	2014-02-28	Completed
A Randomized, Double-blinded Comparison of Iopromide and Iodixanol in Renally Impaired Patients Undergoing Cardiac Catheterization[NCT00926562]	Phase 4	592 participants (Actual)	Interventional	2009-02-28	Completed
A Single Center Observational Study- Incidence and Risk Factors of Acute Kidney Injury After Intravenous Contrast Enhanced Computed Tomography Scans[NCT04606056]		5,000 participants (Anticipated)	Observational	2020-05-31	Recruiting
Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease (ENRICH): A Randomized Controlled Trial[NCT05283512]		254 participants (Anticipated)	Interventional	2022-04-20	Recruiting
Efficacy of Oral Sodium Chloride vs iv Sodium Chloride in the Prevention of Contrast Nephropathy in Outpatients[NCT03476460]	Phase 2	269 participants (Actual)	Interventional	2014-03-01	Completed
Renal Insufficiency Following Contrast Media Administration Trial II (Remedial II): The RenalGuard System in High-Risk Patients for Contrast-Induced Acute Kidney Injury[NCT01098032]	Phase 3	294 participants (Actual)	Interventional	2009-01-31	Completed
Perioperative Use of N-acetylcysteine to Prevent Acute Kidney Injury in Patients With Pre-existing Moderate Renal Insufficiency Following Cardiac Surgery[NCT05555511]		46 participants (Anticipated)	Interventional	2022-08-26	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Clinical neurological deterioration not attributable to other causes, mores specifically not due to re-bleeding, hydrocephalus, or metabolic changes. (NCT03377049)
Timeframe: Day 1-14 during the hospitalization

Percent Change in Left Hemisphere Brain Imaging Maps

Intervention	Participants (Count of Participants)
Acetazolamide Challenge	2

Using perfusion map values, relative percent change will be calculated (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour

Percent Change in Right Hemisphere Brain Imaging Maps

Intervention	percent change (Mean)
Acetazolamide Challenge	19.785

Using perfusion map values, relative percent change will be calculated (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour

Relative Percent Change in Cerebral Blood Flow

Intervention	percent change (Mean)
Acetazolamide Challenge	21.659

The data that will be statistically compared is the pre-diamox perfusion in comparison to the post-diamox perfusion. A statistically significant change increase in CBF represents an appropriate response to Diamox. Lack of change in CBF or decrease in CBF could be suggestive of potential for developing vasospasm. (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour

Number of Participants With Contrast-induced Acute Kidney Injury

Intervention	percent change (Mean)
Acetazolamide Challenge	20.722

The primary outcome measure will be the rate of development of CI-AKI in the 2 study arms (number of participants). CI-AKI is defined as an increase in the serum creatinine concentration >=0.3 mg/dL from the baseline value at 48 hours after administration of the contrast media or the need for dialysis. (NCT01098032)
Timeframe: at 48 hours following contrast exposure

Intervention	participants (Number)
Systemic Alone Therapy Group	146
RenalGuard System Group	146

Article	Year
Iopromide and Iodixanol in the Development of Postoperative Contrast Nephropathy in Patients with Renal Insufficiency: A Meta-Analysis. Journal of healthcare engineering, 2022, Volume: 2022 Topics: Contrast Media; Creatinine; Female; Humans; Iohexol; Kidney Diseases; Male; Renal Insufficiency; Ret	2022
[Measurement of glomerular filtration rate using a reference method]. Annales de biologie clinique, 2019, 08-01, Volume: 77, Issue:4 Topics: Biomarkers; Creatinine; France; Glomerular Filtration Rate; Humans; Internationality; Iohexol; Kidne	2019
Iodixanol versus iopromide in patients with renal insufficiency undergoing coronary angiography with or without PCI. Medicine, 2018, Volume: 97, Issue:18 Topics: Contrast Media; Coronary Angiography; Creatinine; Humans; Iohexol; Kidney Diseases; Percutaneous Cor	2018
Measurement of glomerular filtration rate in cats: methods and advantages over routine markers of renal function. Journal of feline medicine and surgery, 2014, Volume: 16, Issue:9 Topics: Animals; Biomarkers; Cat Diseases; Cats; Creatinine; Glomerular Filtration Rate; Humans; Iohexol; Ki	2014
The relative renal safety of iodixanol compared with low-osmolar contrast media: a meta-analysis of randomized controlled trials. JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:7 Topics: Aged; Aged, 80 and over; Consumer Product Safety; Contrast Media; Evidence-Based Medicine; Female; H	2009
[Glomerular filtration markers in pediatrics]. Revue medicale de la Suisse romande, 2002, Volume: 122, Issue:12 Topics: Age Factors; beta 2-Microglobulin; Biomarkers; Child; Creatinine; Cystatin C; Cystatins; Female; Glo	2002
[Evaluation of glomerular filtration rate in clinical practice]. Revue medicale de Liege, 2003, Volume: 58, Issue:2 Topics: Chromium Radioisotopes; Contrast Media; Creatinine; Glomerular Filtration Rate; Humans; Inulin; Iohe	2003
Effect of nonionic radiocontrast agents on the occurrence of contrast-induced nephropathy in patients with mild-moderate chronic renal insufficiency: pooled analysis of the randomized trials. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2005, Volume: 65, Issue:3 Topics: Contrast Media; Humans; Iohexol; Iopamidol; Kidney Diseases; Randomized Controlled Trials as Topic;	2005
Contrast media and nephropathy: findings from systematic analysis and Food and Drug Administration reports of adverse effects. Investigative radiology, 2006, Volume: 41, Issue:8 Topics: Bayes Theorem; Contrast Media; Humans; Iohexol; Iopamidol; Kidney Diseases; Logistic Models; Odds Ra	2006
Estimating and measuring glomerular filtration rate in children. Current opinion in nephrology and hypertension, 2008, Volume: 17, Issue:3 Topics: Biomarkers; Child; Cimetidine; Creatinine; Cystatin C; Cystatins; Glomerular Filtration Rate; Humans	2008

Article	Year
Comparison of the nephrotoxic effects of iodixanol versus iohexol in patients with chronic heart failure undergoing coronary angiography or angioplasty. Journal of interventional cardiology, 2017, Volume: 30, Issue:3 Topics: Adult; Angioplasty, Balloon, Coronary; China; Contrast Media; Coronary Angiography; Double-Blind Met	2017
Optimization of Split-Bolus CT Urography: Effect of Differences in Allocation of Contrast Medium and Prolongation of Imaging Delay. AJR. American journal of roentgenology, 2017, Volume: 209, Issue:1 Topics: Adult; Aged; Contrast Media; Female; Humans; Iohexol; Kidney Cortex; Kidney Diseases; Male; Middle A	2017
Iodixanol versus iopromide in cancer patients: Evidence from a randomized clinical trial. Journal of cellular physiology, 2018, Volume: 233, Issue:3 Topics: Adolescent; Adult; Aged; Contrast Media; Female; Glomerular Filtration Rate; Humans; Iohexol; Italy;	2018
Contrast between innovator drug- and generic drug-induced renal dysfunction on coronary angiography (CONTRAST study). Heart and vessels, 2014, Volume: 29, Issue:5 Topics: Aged; Albuminuria; Biomarkers; C-Reactive Protein; Contrast Media; Coronary Angiography; Creatinine;	2014
Comparison of short-term infusion regimens of N-acetylcysteine plus intravenous fluids, sodium bicarbonate plus intravenous fluids, and intravenous fluids alone for prevention of contrast-induced nephropathy in the emergency department. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2014, Volume: 21, Issue:6 Topics: Acetylcysteine; Adolescent; Adult; Aged; Aged, 80 and over; Contrast Media; Drug Administration Sche	2014
Comparison between three supportive treatments for prevention of contrast-induced nephropathy in high-risk patients undergoing coronary angiography. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2014, Volume: 25, Issue:6 Topics: Acetylcysteine; Aged; Antioxidants; Biomarkers; Blood Urea Nitrogen; Contrast Media; Coronary Angiog	2014
Diastolic dysfunction and contrast-induced nephropathy in patients undergoing coronary angiography. Herz, 2015, Volume: 40 Suppl 3 Topics: Contrast Media; Coronary Angiography; Echocardiography; Female; Humans; Iohexol; Kidney Diseases; Ma	2015
Preventive effect of oral nicorandil on contrast-induced nephropathy in patients with renal insufficiency undergoing elective cardiac catheterization. Heart and vessels, 2016, Volume: 31, Issue:11 Topics: Administration, Oral; Aged; Biomarkers; Cardiac Catheterization; Chi-Square Distribution; China; Con	2016
Nephrotoxic effects of iodixanol and iopromide in patients with abnormal renal function receiving N-acetylcysteine and hydration before coronary angiography and intervention: a randomized trial. Internal medicine journal, 2009, Volume: 39, Issue:1 Topics: Acetylcysteine; Aged; Angioplasty, Balloon; Contrast Media; Coronary Angiography; Creatinine; Double	2009
A prospective, double-blind, randomized, controlled trial on the efficacy and cardiorenal safety of iodixanol vs. iopromide in patients with chronic kidney disease undergoing coronary angiography with or without percutaneous coronary intervention. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, Dec-01, Volume: 72, Issue:7 Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Contrast Media;	2008
Assessment of the effect of radio contrast media on resistive index of renal artery by color doppler sonography. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2009, Volume: 20, Issue:1 Topics: Adult; Contrast Media; Female; Humans; Iohexol; Kidney Diseases; Male; Renal Artery; Triiodobenzoic	2009
High incidence of nephropathy in neurosurgical patients after intra-arterial administration of low-osmolar and iso-osmolar contrast media. Acta radiologica (Stockholm, Sweden : 1987), 2011, May-01, Volume: 52, Issue:4 Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Contrast Media; Diabetes Complications; Double-	2011
Comparison of contrast-induced nephrotoxicity of iodixanol and iopromide in patients with renal insufficiency undergoing coronary angiography. The American journal of cardiology, 2011, Jul-15, Volume: 108, Issue:2 Topics: Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Creatinine; Double-Blind	2011
Renal safety in pediatric imaging: randomized, double-blind phase IV clinical trial of iobitridol 300 versus iodixanol 270 in multidetector CT. Pediatric radiology, 2011, Volume: 41, Issue:11 Topics: Adolescent; Child; Child, Preschool; Contrast Media; Double-Blind Method; Female; Humans; Infant; Io	2011
[Effectiveness of nephroprotection by the selection of contrast media used during vascular interventions in patients with chronic renal failure?]. Zentralblatt fur Chirurgie, 2011, Volume: 136, Issue:5 Topics: Aged; Aged, 80 and over; Angiography; Angioplasty, Balloon; Contrast Media; Cost-Benefit Analysis; C	2011
Comparative investigation of i.v. iohexol and iopamidol: effect on renal function in low-risk outpatients undergoing CT. AJR. American journal of roentgenology, 2012, Volume: 198, Issue:2 Topics: Chi-Square Distribution; Contrast Media; Double-Blind Method; Female; Humans; Injections, Intravenou	2012
N-acetylcysteine for the prevention of contrast-induced nephropathy in the emergency department. Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:19 Topics: Acetylcysteine; Aged; Aged, 80 and over; Contrast Media; Emergency Medical Services; Emergency Servi	2012
Renal tolerability of iopromide and iodixanol in 562 renally impaired patients undergoing cardiac catheterisation: the DIRECT study. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2012, Nov-22, Volume: 8, Issue:7 Topics: Aged; Biomarkers; Cardiac Catheterization; China; Contrast Media; Coronary Angiography; Coronary Art	2012
Renal tolerability of iopromide and iodixanol in 562 renally impaired patients undergoing cardiac catheterisation: the DIRECT study. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2012, Nov-22, Volume: 8, Issue:7 Topics: Aged; Biomarkers; Cardiac Catheterization; China; Contrast Media; Coronary Angiography; Coronary Art	2012
Renal tolerability of iopromide and iodixanol in 562 renally impaired patients undergoing cardiac catheterisation: the DIRECT study. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2012, Nov-22, Volume: 8, Issue:7 Topics: Aged; Biomarkers; Cardiac Catheterization; China; Contrast Media; Coronary Angiography; Coronary Art	2012
Renal tolerability of iopromide and iodixanol in 562 renally impaired patients undergoing cardiac catheterisation: the DIRECT study. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2012, Nov-22, Volume: 8, Issue:7 Topics: Aged; Biomarkers; Cardiac Catheterization; China; Contrast Media; Coronary Angiography; Coronary Art	2012
Two-center clinical study on the effect of chronic renal impairment on safety of iopromide 300 mg iodine/ml. Academic radiology, 2002, Volume: 9 Suppl 2 Topics: Contrast Media; Creatinine; Humans; Iohexol; Kidney Diseases; Physical Examination; Tomography, X-Ra	2002
Nephrotoxic effects in high-risk patients undergoing angiography. The New England journal of medicine, 2003, Feb-06, Volume: 348, Issue:6 Topics: Aged; Angiography; Contrast Media; Creatinine; Diabetes Mellitus; Double-Blind Method; Female; Human	2003
Renal colic: a prospective evaluation of non-enhanced spiral CT versus intravenous pyelography. Australasian radiology, 2003, Volume: 47, Issue:1 Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Colic; Contrast Media; Humans; Injections	2003
Using a saline chaser to decrease contrast media in abdominal CT. AJR. American journal of roentgenology, 2003, Volume: 180, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Cost Savings; Female; Humans; Iohexol; Kidney Diseas	2003
Standard vs double dose of N-acetylcysteine to prevent contrast agent associated nephrotoxicity. European heart journal, 2004, Volume: 25, Issue:3 Topics: Acetylcysteine; Aged; Contrast Media; Drug Administration Schedule; Female; Free Radical Scavengers;	2004
Cost-effectiveness of iodixanol in patients at high risk of contrast-induced nephropathy. American heart journal, 2005, Volume: 149, Issue:2 Topics: Acute Kidney Injury; Angiography; Contrast Media; Coronary Angiography; Cost-Benefit Analysis; Healt	2005
Prehydration alone is sufficient to prevent contrast-induced nephropathy after day-only angiography procedures--a randomised controlled trial. Heart, lung & circulation, 2005, Volume: 14, Issue:4 Topics: Acetylcysteine; Aged; Aged, 80 and over; Angiography; Cardiovascular Diseases; Contrast Media; Cost-	2005
A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:8 Topics: Administration, Oral; Aged; Contrast Media; Creatinine; Diabetic Nephropathies; Diuretics; Drug Syne	2006
A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:8 Topics: Administration, Oral; Aged; Contrast Media; Creatinine; Diabetic Nephropathies; Diuretics; Drug Syne	2006
A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:8 Topics: Administration, Oral; Aged; Contrast Media; Creatinine; Diabetic Nephropathies; Diuretics; Drug Syne	2006
A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:8 Topics: Administration, Oral; Aged; Contrast Media; Creatinine; Diabetic Nephropathies; Diuretics; Drug Syne	2006
Trimetazidine in the prevention of contrast-induced nephropathy after coronary procedures. Heart (British Cardiac Society), 2007, Volume: 93, Issue:6 Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Cardiac Catheterization; Contrast Media; Coron	2007
Nephrotoxicity of iso-osmolar versus low-osmolar contrast media is equal in low risk patients. Clinical nephrology, 2006, Volume: 66, Issue:5 Topics: Acetylglucosaminidase; Chi-Square Distribution; Contrast Media; Coronary Angiography; Creatinine; Do	2006
Prophylactic hemodialysis for the prevention of contrast-induced nephropathy after coronary angiography. Nature clinical practice. Nephrology, 2008, Volume: 4, Issue:3 Topics: Adult; Contrast Media; Coronary Angiography; Humans; Iohexol; Kidney Diseases; Prospective Studies;	2008
Iso-osmolality versus low-osmolality iodinated contrast medium at intravenous contrast-enhanced CT: effect on kidney function. Radiology, 2008, Volume: 248, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Contrast Media; Creatinine; Female; Glomerular Filtratio	2008
Plasma clearance of nonradioactive iohexol as a measure of glomerular filtration rate. Journal of the American Society of Nephrology : JASN, 1995, Volume: 6, Issue:2 Topics: Adult; Contrast Media; Female; Glomerular Filtration Rate; Humans; Inulin; Iohexol; Kidney; Kidney D	1995
Adverse reactions to contrast media: factors that determine the cost of treatment. AJR. American journal of roentgenology, 1993, Volume: 161, Issue:5 Topics: Adult; Aged; Cardiovascular Diseases; Contrast Media; Coronary Angiography; Diatrizoate Meglumine; D	1993
Does prophylactic treatment with felodipine, a calcium antagonist, prevent low-osmolar contrast-induced renal dysfunction in hydrated diabetic and nondiabetic patients with normal or moderately reduced renal function? Scandinavian journal of urology and nephrology, 1996, Volume: 30, Issue:1 Topics: Aged; Aged, 80 and over; Angiography; Calcium Channel Blockers; Contrast Media; Creatinine; Diabetes	1996
Determination of glomerular filtration rate with Visipaque in patients with severely reduced renal function. European radiology, 1996, Volume: 6, Issue:6 Topics: Adult; Aged; Contrast Media; Glomerular Filtration Rate; Humans; Iodine; Iohexol; Iothalamic Acid; K	1996
Comparison of the nephrotoxicity between ioversol and iohexol. International urology and nephrology, 1996, Volume: 28, Issue:5 Topics: Contrast Media; Female; Humans; Infusions, Intravenous; Iohexol; Kidney; Kidney Diseases; Kidney Fun	1996
Precision of plasma clearance of iohexol for estimation of GFR in patients with renal disease. Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:2 Topics: Adult; Chronic Disease; Female; Glomerular Filtration Rate; Humans; Iohexol; Kidney Diseases; Male;	1998
The renal effect of low-dose dopamine in high-risk patients undergoing coronary angiography. Journal of the American College of Cardiology, 1999, Nov-15, Volume: 34, Issue:6 Topics: Cardiotonic Agents; Contrast Media; Coronary Angiography; Creatinine; Diabetes Complications; Dopami	1999
Comparison of iodixanol and iohexol in renal impairment. The British journal of radiology, 1999, Volume: 72, Issue:859 Topics: Aged; Contrast Media; Creatinine; Female; Humans; Iohexol; Kidney; Kidney Diseases; Male; Middle Age	1999
Low- versus high-osmolality contrast media. Acta radiologica (Stockholm, Sweden : 1987), 2000, Volume: 41, Issue:5 Topics: Adult; Aorta; Aortic Diseases; Aortography; Contrast Media; Female; Humans; Iliac Artery; Injections	2000
Lopromide one-sample clearance as a measure of glomerular filtration rate. Clinical physiology and functional imaging, 2002, Volume: 22, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Body Surface Area; Contrast Media; Female; Glomerular Filtration Rat	2002
Diagnostic efficacy of excretory urography with low-dose, nonionic contrast media. Radiology, 1992, Volume: 182, Issue:3 Topics: Contrast Media; Costs and Cost Analysis; Diatrizoate; Evaluation Studies as Topic; Humans; Iohexol;	1992
Clinical experience with iohexol versus iopromide in excretory urography. Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. Erganzungsband, 1989, Volume: 128 Topics: Adolescent; Adult; Aged; Contrast Media; Female; Humans; Iohexol; Kidney Diseases; Male; Middle Aged	1989
Nephrotoxicity of high- and low-osmolality contrast media. Nephron, 1988, Volume: 48, Issue:4 Topics: Adult; Aged; Contrast Media; Coronary Angiography; Diatrizoate; Female; Humans; Iohexol; Ioxaglic Ac	1988

Article	Year
Glomerular filtration rate in children and young adults with haemato-oncological disease and infection is best described by three-compartment iohexol model. Pediatric blood & cancer, 2022, Volume: 69, Issue:1 Topics: Adolescent; Adult; Child; Glomerular Filtration Rate; Humans; Infections; Iohexol; Kidney Diseases;	2022
Calorie Restriction Protects against Contrast-Induced Nephropathy via SIRT1/GPX4 Activation. Oxidative medicine and cellular longevity, 2021, Volume: 2021 Topics: Animals; Apoptosis; Caloric Restriction; Contrast Media; Cytokines; Disease Models, Animal; Enzyme A	2021
Advancement of pharmacokinetic models of iohexol in patients aged 70 years or older with impaired kidney function. Scientific reports, 2021, 11-22, Volume: 11, Issue:1 Topics: Aged; Bayes Theorem; Contrast Media; Creatinine; Female; Glomerular Filtration Rate; Humans; Iohexol	2021
A Combination of Iohexol Treatment and Ionizing Radiation Exposure Enhances Kidney Injury in Contrast-Induced Nephropathy by Increasing DNA Damage. Radiation research, 2022, 04-01, Volume: 197, Issue:4 Topics: Animals; Contrast Media; DNA Damage; Iohexol; Kidney; Kidney Diseases; Mice; Radiation, Ionizing	2022
Estimating Analytical Errors of Glomerular Filtration Rate Measurement. Clinical chemistry, 2022, 09-01, Volume: 68, Issue:9 Topics: Biomarkers; Glomerular Filtration Rate; Humans; Iohexol; Kidney Diseases; Kidney Function Tests	2022
Contrast media-induced nephropathy in Tunisia: prospective case-control study with cardio-nephrological monitoring. The Pan African medical journal, 2023, Volume: 45 Topics: Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Case-Control Studies; Contrast Media	2023
Comparative physiology of glomerular filtration rate by plasma clearance of exogenous creatinine and exo-iohexol in six different avian species. Scientific reports, 2019, 12-23, Volume: 9, Issue:1 Topics: Animals; Biomarkers; Bird Diseases; Birds; Chickens; Columbidae; Creatinine; Ducks; Early Diagnosis;	2019
AdipoRon, an adiponectin receptor agonist, protects contrast-induced nephropathy by suppressing oxidative stress and inflammation via activation of the AMPK pathway. Clinical and experimental nephrology, 2020, Volume: 24, Issue:11 Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Blood Urea Nitrogen; Cell Adhesion Molecules; Cel	2020
Measured glomerular filtration rate does not improve prediction of mortality by cystatin C and creatinine. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2017, Apr-01, Volume: 32, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Comorbidity; Creatinine; Cystatin C; Female;	2017
Role of CT scan in diagnosis of renal lymphangiectasia: our single-center experience. Renal failure, 2017, Volume: 39, Issue:1 Topics: Adult; Aged; Contrast Media; Female; Humans; Iohexol; Kidney Diseases; Lymphangiectasis; Male; Middl	2017
Histopathological evaluation and redox assessment in blood and kidney tissues in a rabbit contrast-induced nephrotoxicity model. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 108, Issue:Pt A Topics: Animals; Biomarkers; Contrast Media; Creatinine; Iohexol; Kidney; Kidney Diseases; Male; Oxidation-R	2017
Iohexol plasma clearance simplified by dried blood spot testing. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2018, 09-01, Volume: 33, Issue:9 Topics: Dried Blood Spot Testing; Female; Glomerular Filtration Rate; Humans; Iohexol; Kidney; Kidney Diseas	2018
Serum Corin Level Is Associated With Subsequent Decline in Renal Function in Patients With Suspected Coronary Artery Disease. Journal of the American Heart Association, 2018, 05-04, Volume: 7, Issue:10 Topics: Aged; Aged, 80 and over; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease;	2018
Attenuation and Degree of Enhancement With Conventional 120-kVp Polychromatic CT and 70-keV Monochromatic Rapid Kilovoltage-Switching Dual-Energy CT in Cystic and Solid Renal Masses. AJR. American journal of roentgenology, 2018, Volume: 211, Issue:4 Topics: Aged; Contrast Media; Diagnosis, Differential; Female; Humans; Iohexol; Iopamidol; Kidney Diseases;	2018
The role of nuclear factor erythroid-2-related factor 2 expression in radiocontrast-induced nephropathy. Scientific reports, 2019, 02-22, Volume: 9, Issue:1 Topics: Animals; Caspase 3; Cell Death; Cell Line; Cell Survival; Contrast Media; Creatinine; Cytochromes c;	2019
CHA2DS2-VASC score as a preprocedural predictor of contrast-induced nephropathy among patients with chronic total occlusion undergoing percutaneous coronary intervention: a single-center experience. BMC cardiovascular disorders, 2019, 03-29, Volume: 19, Issue:1 Topics: Aged; Biomarkers; Blood Pressure; China; Chronic Disease; Contrast Media; Coronary Angiography; Coro	2019
Glomerular filtration rate in evaluation of the effect of iodinated contrast media on renal function. AJR. American journal of roentgenology, 2013, Volume: 200, Issue:4 Topics: Adult; Aged; Contrast Media; Creatinine; Female; Glomerular Filtration Rate; Humans; Injections, Int	2013
Prevention of contrast-induced nephropathy by N-acetylcysteine in critically ill patients: different definitions, different results. Journal of critical care, 2013, Volume: 28, Issue:5 Topics: Acetylcysteine; Adult; Aged; Contrast Media; Creatinine; Critical Illness; Cystatin C; Female; Free	2013
Anemia and the risk of contrast-induced nephropathy in patients with renal insufficiency undergoing contrast-enhanced MDCT. European journal of radiology, 2013, Volume: 82, Issue:10 Topics: Acute Kidney Injury; Aged; Anemia; Causality; Comorbidity; Contrast Media; Drug-Related Side Effects	2013
Incidence of contrast-induced nephropathy in hospitalised patients with cancer. European radiology, 2014, Volume: 24, Issue:1 Topics: Adult; Contrast Media; Female; Humans; Incidence; Inpatients; Iohexol; Kidney Diseases; Male; Middle	2014
Incidence of contrast material-induced nephropathy after neuroendovascular procedures. Radiology, 2014, Volume: 273, Issue:3 Topics: Contrast Media; Creatinine; Endovascular Procedures; Female; Glomerular Filtration Rate; Humans; Inc	2014
Cystatin C as biomarker of contrast-induced nephropathy in pediatric cardiac angiography. Turkish journal of medical sciences, 2014, Volume: 44, Issue:2 Topics: Acute-Phase Proteins; Adolescent; Biomarkers; Case-Control Studies; Child; Child, Preschool; Contras	2014
Estimating GFR in adult patients with hematopoietic cell transplant: comparison of estimating equations with an iohexol reference standard. Clinical journal of the American Society of Nephrology : CJASN, 2015, Apr-07, Volume: 10, Issue:4 Topics: Adult; Aged; Biomarkers; Contrast Media; Creatinine; Cystatin C; Female; Glomerular Filtration Rate;	2015
Nephroprotective potential of carnitine against glycerol and contrast-induced kidney injury in rats through modulation of oxidative stress, proinflammatory cytokines, and apoptosis. The British journal of radiology, 2016, Volume: 89, Issue:1058 Topics: Animals; Apoptosis; Blood Urea Nitrogen; Carnitine; Contrast Media; Creatinine; Cytokines; Glycerol;	2016
Iohexol clearance is superior to creatinine-based renal function estimating equations in detecting short-term renal function decline in chronic heart failure. Croatian medical journal, 2015, Volume: 56, Issue:6 Topics: Aged; Aged, 80 and over; Chronic Disease; Creatinine; Female; Glomerular Filtration Rate; Heart Fail	2015
Incidence of Contrast-Induced Nephropathy After Renal Graft Catheter Arteriography Using Iodine-Based Contrast Medium. AJR. American journal of roentgenology, 2016, Volume: 206, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiography; Contrast Media; Creatinine; Female; Graft R	2016
Is there any role of epithelial to mesenchymal transition in the pathogenesis of contrast nephropathy? Renal failure, 2016, Volume: 38, Issue:8 Topics: Cell Differentiation; Cell Line; Collagen Type I; Collagen Type I, alpha 1 Chain; Connective Tissue	2016
Inaccuracy of GFR predictions by plasma cystatin C in patients without kidney dysfunction and in advanced kidney disease. Clinical nephrology, 2008, Volume: 69, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Child; Child, Preschool; Cystatin C; Cystati	2008
alpha2-Adrenergic agonists protect against radiocontrast-induced nephropathy in mice. American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:3 Topics: Adrenergic alpha-Agonists; Animals; Cell Line; Clonidine; Contrast Media; Dexmedetomidine; Iohexol;	2008
Evaluation of the Modification of Diet in Renal Disease equation (eGFR) against simultaneous, dual-marker multi-sample measurements of glomerular filtration rate. Annals of clinical biochemistry, 2009, Volume: 46, Issue:Pt 1 Topics: Adult; Aged; Edetic Acid; Glomerular Filtration Rate; Humans; Iohexol; Kidney Diseases; Middle Aged	2009
Retention of iodine and expression of biomarkers for renal damage in the kidney after application of iodinated contrast media in rats. Investigative radiology, 2009, Volume: 44, Issue:2 Topics: Animals; Cell Adhesion Molecules; Contrast Media; Dose-Response Relationship, Drug; Heme Oxygenase (	2009
Sodium bicarbonate versus normal saline for protection against contrast nephropathy. Renal failure, 2009, Volume: 31, Issue:2 Topics: Aged; Cardiac Catheterization; Contrast Media; Coronary Angiography; Creatinine; Electrolytes; Glome	2009
Background fluctuation of kidney function versus contrast-induced nephrotoxicity. AJR. American journal of roentgenology, 2009, Volume: 192, Issue:3 Topics: Analysis of Variance; Contrast Media; Creatinine; Female; Glomerular Filtration Rate; Humans; Incide	2009
Renal-adrenal fusion: instance of an adrenal adenoma mimicking a solid renal mass at CT--case report. Radiology, 2009, Volume: 251, Issue:3 Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aged; Contrast Media; Diagnosis, Differential; Fem	2009
Validation of a new plasma cystatin C-based formula and the Modification of Diet in Renal Disease creatinine-based formula for determination of glomerular filtration rate. Scandinavian journal of urology and nephrology, 2009, Volume: 43, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Algorithms; Biomarkers; Contrast Media; Creatinine; Cystatin C; Fema	2009
Association of proteinuria with race, cause of chronic kidney disease, and glomerular filtration rate in the chronic kidney disease in children study. Clinical journal of the American Society of Nephrology : CJASN, 2009, Volume: 4, Issue:4 Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Black	2009
Proteinuria: not a small problem in the little ones. Clinical journal of the American Society of Nephrology : CJASN, 2009, Volume: 4, Issue:4 Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Black	2009
Is the use of intravenous contrast material truly safe in patients with impaired renal function? Radiology, 2009, Volume: 251, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Contrast Media; Creatinine; Female; Glomerular Filtratio	2009
[Delay in implementation of international guidelines for computed tomographies with iodinated contrast media]. Ugeskrift for laeger, 2009, Apr-20, Volume: 171, Issue:17 Topics: Antineoplastic Agents; Carboplatin; Cisplatin; Contrast Media; Creatinine; Guideline Adherence; Huma	2009
The protective role of telmisartan against nephrotoxicity induced by X-ray contrast media in rat model. Acta radiologica (Stockholm, Sweden : 1987), 2009, Volume: 50, Issue:7 Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; B	2009
The incidence of nephropathy in patients undergoing transcatheter aortic valve implantation. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009, Oct-01, Volume: 74, Issue:4 Topics: Aortic Valve Stenosis; Cardiac Catheterization; Contrast Media; Glomerular Filtration Rate; Heart Va	2009
Impact of the definition utilized on the rate of contrast-induced nephropathy in percutaneous coronary intervention. The American journal of cardiology, 2009, Jun-15, Volume: 103, Issue:12 Topics: Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Coronary Disease; Female; Foll	2009
Comparison of plasma clearance of exogenous creatinine, exo-iohexol, and endo-iohexol over a range of glomerular filtration rates expected in cats. Journal of feline medicine and surgery, 2009, Volume: 11, Issue:12 Topics: Analysis of Variance; Animals; Cat Diseases; Cats; Creatinine; Female; Glomerular Filtration Rate; H	2009
[Contrast-induced nephropathy in coronarography of patients with type 2 diabetes mellitus: risk factors, prognostic significance, prophylactic approaches]. Terapevticheskii arkhiv, 2009, Volume: 81, Issue:8 Topics: Contrast Media; Coronary Angiography; Creatinine; Diabetes Mellitus, Type 2; Female; Glomerular Filt	2009
Optimizing iohexol plasma disappearance curves to measure the glomerular filtration rate in children with chronic kidney disease. Kidney international, 2010, Volume: 77, Issue:1 Topics: Adolescent; Child; Chronic Disease; Female; Glomerular Filtration Rate; Humans; Iohexol; Kidney Dise	2010
Evaluation of a single sampling method for estimation of plasma iohexol clearance in dogs and cats with various kidney functions. The Journal of veterinary medical science, 2010, Volume: 72, Issue:3 Topics: Animals; Animals, Laboratory; Biomarkers; Cat Diseases; Cats; Colorimetry; Dog Diseases; Dogs; Glome	2010
Study Protocol--accurate assessment of kidney function in Indigenous Australians: aims and methods of the eGFR study. BMC public health, 2010, Feb-19, Volume: 10 Topics: Adult; Australia; Body Composition; Body Size; Contrast Media; Cross-Sectional Studies; Databases, F	2010
Risk of nephropathy after consumption of nonionic contrast media by children undergoing cardiac angiography: a prospective study. Pediatric cardiology, 2010, Volume: 31, Issue:5 Topics: Adolescent; Chi-Square Distribution; Child; Child, Preschool; Contrast Media; Coronary Angiography;	2010
Assessments of factors that affect glomerular filtration rate and indirect markers of renal function in dogs and cats. The Journal of veterinary medical science, 2010, Volume: 72, Issue:9 Topics: Aging; Animals; Biomarkers; Body Weight; Cat Diseases; Cats; Creatinine; Dog Diseases; Dogs; Glomeru	2010
Constriction of the vasa recta, the vessels supplying the area at risk for acute kidney injury, by four different iodinated contrast media, evaluating ionic, nonionic, monomeric and dimeric agents. Investigative radiology, 2010, Volume: 45, Issue:8 Topics: Analysis of Variance; Angiotensin II; Animals; Contrast Media; Diatrizoate; Humans; Iohexol; Ioxagli	2010
Slope-only glomerular filtration rate and single-sample glomerular filtration rate as measurements of the ratio of glomerular filtration rate to extracellular fluid volume. Nephrology (Carlton, Vic.), 2010, Volume: 15, Issue:3 Topics: Body Surface Area; Edetic Acid; Extracellular Fluid; Female; Glomerular Filtration Rate; Humans; Ioh	2010
N-acetylcysteine attenuates iodine contrast agent-induced nephropathy in 5/6-nephrectomized rats. Kidney & blood pressure research, 2010, Volume: 33, Issue:2 Topics: Acetylcysteine; Animals; Contrast Media; Iodine; Iohexol; Iothalamate Meglumine; Kidney Diseases; Ne	2010
Perinephric hematoma: semi-automated quantification of volume on MDCT: a feasibility study. Abdominal imaging, 2011, Volume: 36, Issue:2 Topics: Abdominal Injuries; Adult; Aged; Aged, 80 and over; Contrast Media; Feasibility Studies; Female; Hem	2011
Use of gadolinium diethylene triamine penta-acetic acid, as measured by ELISA, in the determination of glomerular filtration rates in cats. Journal of feline medicine and surgery, 2010, Volume: 12, Issue:10 Topics: Animals; Blood Urea Nitrogen; Cat Diseases; Cats; Chronic Disease; Contrast Media; Creatinine; Enzym	2010
Dyslipidemia in children with chronic kidney disease. Kidney international, 2010, Volume: 78, Issue:11 Topics: Adolescent; Age Factors; Biomarkers; Body Mass Index; Chi-Square Distribution; Child; Child, Prescho	2010
Risk stratification nomogram for nephropathy after abdominal contrast-enhanced computed tomography. The American journal of emergency medicine, 2011, Volume: 29, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Creatinine; Emergency Service, Hospital; Female; Hum	2011
Comparison of plasma clearance of iohexol and urinary clearance of inulin for measurement of GFR in children. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2011, Volume: 57, Issue:1 Topics: Child; Contrast Media; Creatinine; Glomerular Filtration Rate; Humans; Inulin; Iohexol; Kidney; Kidn	2011
Inaccuracies of creatinine and creatinine-based equations in candidates for liver transplantation with low creatinine: impact on the model for end-stage liver disease score. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2010, Volume: 16, Issue:10 Topics: Adult; Aged; Biomarkers; Contrast Media; Creatinine; Female; France; Glomerular Filtration Rate; Hea	2010
The ratio of contrast volume to glomerular filtration rate predicts outcomes after percutaneous coronary intervention for ST-segment elevation acute myocardial infarction. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2011, Aug-01, Volume: 78, Issue:2 Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Biomarkers; Chi-Square Distribution; Contra	2011
[Using cytoflavin for correcting x-ray contrasting agent-induced nephropathy]. Eksperimental'naia i klinicheskaia farmakologiia, 2010, Volume: 73, Issue:10 Topics: Animals; Contrast Media; Cytoprotection; Drug Combinations; Flavin Mononucleotide; Inosine Diphospha	2010
Iodine quantification with dual-energy CT: phantom study and preliminary experience with renal masses. AJR. American journal of roentgenology, 2011, Volume: 196, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Contrast Media; Female; Humans; Image Processi	2011
Renal effects of bicarbonate versus saline infusion for iso- and lowosmolar contrast media in rats. Investigative radiology, 2011, Volume: 46, Issue:11 Topics: Analysis of Variance; Animals; Bicarbonates; Contrast Media; Dose-Response Relationship, Drug; Glome	2011
Universal GFR determination based on two time points during plasma iohexol disappearance. Kidney international, 2011, Volume: 80, Issue:4 Topics: Adolescent; Age Factors; Body Size; Body Surface Area; Canada; Child; Contrast Media; Female; Glomer	2011
GFR normalized to total body water allows comparisons across genders and body sizes. Journal of the American Society of Nephrology : JASN, 2011, Volume: 22, Issue:8 Topics: Body Size; Body Surface Area; Body Water; Body Weight; Cohort Studies; Female; Glomerular Filtration	2011
Assessing glomerular filtration rate in hospitalized patients: a comparison between CKD-EPI and four cystatin C-based equations. Clinical journal of the American Society of Nephrology : CJASN, 2011, Volume: 6, Issue:10 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Body Surface Area; Chi-Square Distribution;	2011
Spontaneous suburothelial hemorrhage in coagulopathic patients: CT diagnosis. AJR. American journal of roentgenology, 2011, Volume: 197, Issue:5 Topics: Adult; Aged; Anticoagulants; Contrast Media; Female; Hematoma; Hematuria; Hemorrhage; Humans; Iohexo	2011
Occurrence and value of the color Doppler "line sign" after radiofrequency ablation of solid abdominal organs. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2011, Volume: 30, Issue:11 Topics: Aged; Aged, 80 and over; Catheter Ablation; Contrast Media; Female; Humans; Iohexol; Kidney Diseases	2011
Contrast-induced nephropathy: controlled study by differential GFR measurement in hospitalized patients. Acta radiologica (Stockholm, Sweden : 1987), 2012, Mar-01, Volume: 53, Issue:2 Topics: Blood Urea Nitrogen; Contrast Media; Creatinine; Female; Glomerular Filtration Rate; Humans; Inpatie	2012
"CIN" no more: the use of contrast volume to e-GFR ratio to predict and prevent contrast-induced acute kidney injury. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2012, Jun-01, Volume: 79, Issue:7 Topics: Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Female; Glomerular Filtration	2012
Epidemiology of contrast material-induced nephropathy in the era of hydration. Radiology, 2012, Volume: 263, Issue:3 Topics: Aged; Contrast Media; Female; Glomerular Filtration Rate; Humans; Incidence; Iohexol; Iopamidol; Kid	2012
Epidemiology of contrast material-induced nephropathy in the era of hydration. Radiology, 2012, Volume: 263, Issue:3 Topics: Aged; Contrast Media; Female; Glomerular Filtration Rate; Humans; Incidence; Iohexol; Iopamidol; Kid	2012
Epidemiology of contrast material-induced nephropathy in the era of hydration. Radiology, 2012, Volume: 263, Issue:3 Topics: Aged; Contrast Media; Female; Glomerular Filtration Rate; Humans; Incidence; Iohexol; Iopamidol; Kid	2012
Epidemiology of contrast material-induced nephropathy in the era of hydration. Radiology, 2012, Volume: 263, Issue:3 Topics: Aged; Contrast Media; Female; Glomerular Filtration Rate; Humans; Incidence; Iohexol; Iopamidol; Kid	2012
Pathophysiology of the contrast media-induced nephropathy (CIN) in patients undergoing coronary interventions. Clinical hemorheology and microcirculation, 2013, Volume: 53, Issue:1-2 Topics: Animals; Contrast Media; Coronary Angiography; Humans; Iohexol; Kidney; Kidney Diseases; Kidney Fail	2013
Kidney injury biomarkers in hypertensive, diabetic, and nephropathy rat models treated with contrast media. Toxicologic pathology, 2013, Volume: 41, Issue:4 Topics: Animals; Biomarkers; Blood Urea Nitrogen; Contrast Media; Diabetes Mellitus; Hypertension; Iohexol;	2013
Simvastatin attenuates contrast-induced nephropathy through modulation of oxidative stress, proinflammatory myeloperoxidase, and nitric oxide. Oxidative medicine and cellular longevity, 2012, Volume: 2012 Topics: Administration, Oral; Animals; Blood Urea Nitrogen; Calcium; Contrast Media; Creatinine; Glutathione	2012
Measuring the glomerular filtration rate in different age groups using iohexol, the protocol from the Belgian iohexol study. Clinical biochemistry, 2013, Volume: 46, Issue:1-2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Contrast Media; Creatinine; Cystatin C; Female; Glomerul	2013
Comparison of pharmacokinetic variables for creatinine and iohexol in dogs with various degrees of renal function. American journal of veterinary research, 2012, Volume: 73, Issue:11 Topics: Animals; Contrast Media; Creatinine; Dog Diseases; Dogs; Female; Glomerular Filtration Rate; Iohexol	2012
Contrast material-induced nephrotoxicity and intravenous low-osmolality iodinated contrast material. Radiology, 2013, Volume: 267, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Contrast Media; Female; Humans;	2013
Contrast material-induced nephrotoxicity and intravenous low-osmolality iodinated contrast material. Radiology, 2013, Volume: 267, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Contrast Media; Female; Humans;	2013
Contrast material-induced nephrotoxicity and intravenous low-osmolality iodinated contrast material. Radiology, 2013, Volume: 267, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Contrast Media; Female; Humans;	2013
Contrast material-induced nephrotoxicity and intravenous low-osmolality iodinated contrast material. Radiology, 2013, Volume: 267, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Contrast Media; Female; Humans;	2013
Predictive performance of renal function equations for patients with chronic kidney disease and normal serum creatinine levels. Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:8 Topics: Adult; Chronic Disease; Contrast Media; Creatinine; Female; Glomerular Filtration Rate; Humans; Iohe	2002
Establishing safeguards for the use of imaging-related drugs. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2002, Aug-01, Volume: 59, Issue:15 Topics: Aged; Contrast Media; Documentation; Humans; Iohexol; Joint Commission on Accreditation of Healthcar	2002
Nephrotoxicity after renal angiography using iodine and gadolinium contrast media in pigs with renal damage. Academic radiology, 2002, Volume: 9 Suppl 2 Topics: Animals; Contrast Media; Gadolinium DTPA; Iohexol; Kidney Diseases; Magnetic Resonance Angiography;	2002
Contrast-agent-induced acute renal dysfunction--is iodixanol the answer? The New England journal of medicine, 2003, Feb-06, Volume: 348, Issue:6 Topics: Contrast Media; Diabetes Mellitus; Humans; Iohexol; Kidney; Kidney Diseases; Triiodobenzoic Acids	2003
Et-A receptor antagonist BQ123 prevents radiocontrast media-induced renal medullary hypoxia. Acta radiologica (Stockholm, Sweden : 1987), 2003, Volume: 44, Issue:1 Topics: Animals; Antihypertensive Agents; Contrast Media; Disease Models, Animal; Endothelin Receptor Antago	2003
Nephropathy induced by contrast medium. The New England journal of medicine, 2003, May-29, Volume: 348, Issue:22 Topics: Angiotensin-Converting Enzyme Inhibitors; Confounding Factors, Epidemiologic; Contrast Media; Creati	2003
[Reduced risk of nepropathy with isoosmolar contrast media]. Lakartidningen, 2003, Jun-05, Volume: 100, Issue:23 Topics: Angiography; Contrast Media; Humans; Iohexol; Kidney; Kidney Diseases; Risk Factors; Triiodobenzoic	2003
[Lowering of nephropathy risk during angiography procedure. What are choice criteria for the radiocontrast media?]. Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2003, Volume: 9, Issue:4 Topics: Aged; Angiography; Contrast Media; Health Status; Humans; Intraoperative Complications; Iohexol; Kid	2003
Radiocontrast nephropathy: is it dose related or not? JPMA. The Journal of the Pakistan Medical Association, 2004, Volume: 54, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Coronary Angiography; Creatinine; Female; Humans; Io	2004
Incidence of contrast nephropathy from cerebral CT angiography and CT perfusion imaging. Neurology, 2005, May-24, Volume: 64, Issue:10 Topics: Cohort Studies; Contrast Media; Creatinine; Humans; Incidence; Infusions, Intravenous; Iohexol; Kidn	2005
Improved estimation of GFR by serum cystatin C in patients undergoing cardiac catheterization. International journal of cardiology, 2005, Jul-10, Volume: 102, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cardiac Catheterization; Contrast Media; Creatinine; Cys	2005
A cystatin C-based formula without anthropometric variables estimates glomerular filtration rate better than creatinine clearance using the Cockcroft-Gault formula. Scandinavian journal of clinical and laboratory investigation, 2005, Volume: 65, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Anthropometry; Biomarkers; Clinical Laboratory Techniques; Contrast	2005
Elevated resistin levels in chronic kidney disease are associated with decreased glomerular filtration rate and inflammation, but not with insulin resistance. Kidney international, 2006, Volume: 69, Issue:3 Topics: Adult; Aged; Biomarkers; Body Composition; Body Mass Index; Case-Control Studies; Chronic Disease; C	2006
A1 adenosine receptor knockout mice are protected against acute radiocontrast nephropathy in vivo. American journal of physiology. Renal physiology, 2006, Volume: 290, Issue:6 Topics: Acute Kidney Injury; Adenosine A1 Receptor Antagonists; Animals; Apoptosis; Cells, Cultured; Contras	2006
Renal function and cardiac angiography. Indian journal of pediatrics, 2006, Volume: 73, Issue:1 Topics: Adolescent; Cardiac Catheterization; Child; Child, Preschool; Contrast Media; Cyanosis; Heart Diseas	2006
Glomerular filtration rate via plasma iohexol disappearance: pilot study for chronic kidney disease in children. Kidney international, 2006, Volume: 69, Issue:11 Topics: Adolescent; Adult; Child; Child, Preschool; Chronic Disease; Glomerular Filtration Rate; Humans; Ioh	2006
Gadolinium contrast media are more nephrotoxic than iodine media. The importance of osmolality in direct renal artery injections. European radiology, 2006, Volume: 16, Issue:12 Topics: Animals; Contrast Media; Gadolinium DTPA; Glomerular Filtration Rate; Half-Life; Injections; Iohexol	2006
Extracellular distribution volumes of hydrophilic solutes used to measure the glomerular filtration rate: comparison between chromium-51-EDTA and iohexol. Physiological measurement, 2007, Volume: 28, Issue:2 Topics: Adult; Aged; Algorithms; Contrast Media; Data Interpretation, Statistical; Diabetes Mellitus; Eating	2007
A review of the natural progression of medullary sponge kidney and a novel grading system based on intravenous urography findings. Urologia internationalis, 2007, Volume: 78, Issue:3 Topics: Adolescent; Adult; Child; Contrast Media; Dilatation, Pathologic; Disease Progression; Female; Human	2007
A practical method of measuring glomerular filtration rate by iohexol clearance using dried capillary blood spots. Nephron. Clinical practice, 2007, Volume: 106, Issue:3 Topics: Adult; Capillaries; Creatinine; Female; Glomerular Filtration Rate; Humans; Iohexol; Kidney Diseases	2007
Case 117: actinomycosis of left kidney with sinus tracts. Radiology, 2007, Volume: 244, Issue:1 Topics: Actinomycosis; Adult; Contrast Media; Diagnosis, Differential; Diatrizoate Meglumine; Humans; Iohexo	2007
Evaluation of Gentian cystatin C reagent on Abbott Ci8200 and calculation of glomerular filtration rate expressed in mL/min/1.73 m(2) from the cystatin C values in mg/L. Scandinavian journal of clinical and laboratory investigation, 2007, Volume: 67, Issue:5 Topics: Clinical Laboratory Techniques; Cystatin C; Cystatins; Glomerular Filtration Rate; Humans; Iohexol;	2007
Comparison of the usefulness of gadodiamide and iodine mixture versus iodinated contrast alone for prevention of contrast-induced nephropathy in patients with chronic kidney disease undergoing coronary angiography. The American journal of cardiology, 2007, Oct-01, Volume: 100, Issue:7 Topics: Aged; Aged, 80 and over; Chronic Disease; Contrast Media; Coronary Angiography; Female; Gadolinium D	2007
New data on the intraindividual variation of cystatin C. Nephron. Clinical practice, 2008, Volume: 108, Issue:4 Topics: Adult; Analysis of Variance; Biomarkers; Creatinine; Cystatin C; Cystatins; Female; Glomerular Filtr	2008
Iodixanol compared to iohexol for contrast procedures: a case-matched retrospective cohort study. Acta radiologica (Stockholm, Sweden : 1987), 2008, Volume: 49, Issue:4 Topics: Aged; Angiography; Case-Control Studies; Chi-Square Distribution; Contrast Media; Creatinine; Female	2008
Conclusion of recent 'osmolality trials' in preventing contrast-induced nephropathy by NAC--what is the standard? Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:7 Topics: Angiography; Contrast Media; Cystatin C; Cystatins; Glomerular Filtration Rate; Humans; Iohexol; Iox	2008
Hemodialysis for elimination of the nonionic contrast medium iohexol after angiography in patients with impaired renal function. Nephron, 1995, Volume: 70, Issue:4 Topics: Adult; Aged; Angiography; Contrast Media; Female; Humans; Iohexol; Kidney Diseases; Male; Middle Age	1995
Renal masses: assessment of corticomedullary-phase and nephrographic-phase CT scans. Radiology, 1995, Volume: 196, Issue:2 Topics: False Positive Reactions; Female; Humans; Image Processing, Computer-Assisted; Iohexol; Kidney Corte	1995
Estimation of glomerular filtration rate in dogs with 99M-Tc-DTPA and iohexol. Research in veterinary science, 1995, Volume: 58, Issue:2 Topics: Animals; Dog Diseases; Dogs; Female; Glomerular Filtration Rate; Iohexol; Kidney Diseases; Male; Tec	1995
[Study on free enzymes and proteins in the urine. Report IV: The effects of Iohexol on elderly patients with renal function disorder]. Hinyokika kiyo. Acta urologica Japonica, 1994, Volume: 40, Issue:6 Topics: Acetylglucosaminidase; Aged; Aged, 80 and over; Aging; Albuminuria; beta 2-Microglobulin; Female; ga	1994
Effects of iotrolan, iopamidol, and iopromide in rats with and without experimental nephropathy. Investigative radiology, 1994, Volume: 29 Suppl 2 Topics: Acetylglucosaminidase; Animals; Contrast Media; Doxorubicin; gamma-Glutamyltransferase; Gentamicins;	1994
Determination of low glomerular filtration rate using iohexol clearance. Investigative radiology, 1994, Volume: 29 Suppl 2 Topics: Glomerular Filtration Rate; Humans; Iohexol; Kidney Diseases	1994
Renal actions of endothelin. Kidney international, 1993, Volume: 44, Issue:2 Topics: Aged; Aged, 80 and over; Amino Acid Sequence; Endothelins; Humans; Iohexol; Kidney; Kidney Diseases;	1993
Administration and dosage of iohexol, a nonionic contrast medium, for dynamic renal computed tomography. Hinyokika kiyo. Acta urologica Japonica, 1993, Volume: 39, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Artifacts; Female; Humans; Infusions, Intravenous; Injections, Intra	1993
Renal effects and nephrotoxicity of contrast media in renal patients. Contributions to nephrology, 1993, Volume: 101 Topics: Adolescent; Adult; Aged; Diatrizoate Meglumine; Female; Hemodynamics; Humans; Injections, Intravenou	1993
Evaluation of iohexol as a marker for the clinical measurement of glomerular filtration rate in dogs. Research in veterinary science, 1996, Volume: 60, Issue:2 Topics: Animals; Automation; Contrast Media; Dog Diseases; Dogs; Glomerular Filtration Rate; Humans; Iohexol	1996
Helical CT of renal masses: the value of delayed scans. AJR. American journal of roentgenology, 1996, Volume: 167, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Image Processing, Computer-Assisted;	1996
Unilateral tubular obstruction: an unusual complication of urographic contrast media. AJR. American journal of roentgenology, 1997, Volume: 169, Issue:6 Topics: Adult; Colic; Contrast Media; Female; Humans; Iohexol; Kidney Diseases; Kidney Tubules; Male; Radiog	1997
Dual-phase helical CT of the kidney: value of the corticomedullary and nephrographic phase for evaluation of renal lesions and preoperative staging of renal cell carcinoma. AJR. American journal of roentgenology, 1997, Volume: 169, Issue:6 Topics: Adult; Carcinoma, Renal Cell; Contrast Media; Female; Humans; Image Processing, Computer-Assisted; I	1997
Urine profiles and kidney histology after ionic and nonionic radiologic and magnetic resonance contrast media in rats with cisplatin nephropathy. Academic radiology, 1995, Volume: 2, Issue:8 Topics: Animals; Antineoplastic Agents; Cisplatin; Contrast Media; Diatrizoate; Disease Models, Animal; Dose	1995
15-year follow-up of reflux nephropathy by imaging. Clinical nephrology, 1998, Volume: 50, Issue:4 Topics: Adult; Albuminuria; Blood Pressure; Cicatrix; Cohort Studies; Contrast Media; Creatinine; Diagnostic	1998
Renal masses--evaluation by amplitude coded colour Doppler sonography and multiphasic contrast-enhanced CT. Acta radiologica (Stockholm, Sweden : 1987), 1999, Volume: 40, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Renal Cell; Contrast Media; Diagnosis, Differential; Fema	1999
Spontaneous renal artery dissection revealed by helical CT angiography. European radiology, 2000, Volume: 10, Issue:5 Topics: Abscess; Aneurysm, False; Angiography; Aortic Dissection; Contrast Media; Diagnosis, Differential; H	2000
Comparison of nephrographic with excretory phase helical computed tomography for detecting and characterizing renal masses. Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 2000, Volume: 51, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Artifacts; Contrast Media; Diatrizoate Meglumine; Female	2000
Effect of dopamine on excretory urographic image quality and the prevention of contrast-induced nephropathy in dogs. The Journal of veterinary medical science, 2001, Volume: 63, Issue:4 Topics: Animals; Blood Urea Nitrogen; Contrast Media; Creatinine; Dog Diseases; Dogs; Dopamine; Iohexol; Kid	2001
No evidence of accelerated loss of kidney function in living kidney donors: results from a cross-sectional follow-up. Transplantation, 2001, Aug-15, Volume: 72, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Cross-Sectional Studies; Female; Follow-Up Studies;	2001
Contrast media clearance in a single kidney measured on multiphasic helical CT: results in 50 patients without acute renal disorder. AJR. American journal of roentgenology, 2002, Volume: 178, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Injections, Intravenous; Iohexol; Ki	2002
Radiographic contrast media induced nephropathy: experimental observations and the protective effect of calcium channel blockers. The British journal of radiology, 2001, Volume: 74, Issue:888 Topics: Animals; Calcium Channel Blockers; Chromium; Contrast Media; Diatrizoate; Diltiazem; Dose-Response R	2001
Nephrotoxicity and tubular effects of contrast media. Contributions to nephrology, 1990, Volume: 83 Topics: Adult; Aged; Alpha-Globulins; Animals; Diatrizoate Meglumine; Humans; Iodine Radioisotopes; Iohexol;	1990
Use of urographic contrast media to determine glomerular filtration rate. Determining the glomerular filtration rate of each kidney with computed tomography and scintigraphy. Investigative radiology, 1991, Volume: 26 Suppl 1 Topics: Adult; Aged; Female; Gamma Cameras; Glomerular Filtration Rate; Humans; Iohexol; Kidney; Kidney Dise	1991
Gentamicin nephropathy and contrast media. A comparison between diatrizoate and iohexol in rats. Acta radiologica (Stockholm, Sweden : 1987), 1990, Volume: 31, Issue:4 Topics: Acetylglucosaminidase; Albuminuria; Animals; Diatrizoate; gamma-Glutamyltransferase; Gentamicins; Gl	1990
Effect of three non-ionic contrast media on rats and rabbits with regard to renal changes. Interspecies comparison. Arzneimittel-Forschung, 1990, Volume: 40, Issue:7 Topics: Animals; Blood Urea Nitrogen; Contrast Media; Creatinine; gamma-Glutamyltransferase; Iohexol; Iopami	1990
Effects on renal hemodynamics and tubular function of the contrast medium iohexol in renal patients. Renal failure, 1990, Volume: 12, Issue:3 Topics: Acetylglucosaminidase; Adult; Aged; Alkaline Phosphatase; Aminopeptidases; CD13 Antigens; Female; ga	1990
Contrast media- and pharmacologic-induced nephropathies. Effects of diatrizoate and iohexol on urine profiles in rats. Investigative radiology, 1990, Volume: 25 Suppl 1 Topics: Albuminuria; Animals; Contrast Media; Diatrizoate; Enzymes; Iohexol; Kidney Diseases; Male; Rats	1990
Adriamycin nephrosis and contrast media. A comparison between diatrizoate and iohexol in rats. Acta radiologica (Stockholm, Sweden : 1987), 1990, Volume: 31, Issue:1 Topics: Animals; Diatrizoate; Doxorubicin; Iohexol; Kidney; Kidney Diseases; Male; Radiography; Rats; Rats,	1990
Contrast media-induced lipid peroxidation in the rat kidney. Investigative radiology, 1989, Volume: 24, Issue:9 Topics: Animals; Contrast Media; Creatinine; Diatrizoate; Glycerol; Iohexol; Kidney; Kidney Diseases; Lipid	1989
Renal embolization: a study of the interaction of contrast media and ethanol. Cardiovascular and interventional radiology, 1987, Volume: 10, Issue:4 Topics: Aged; Drug Interactions; Embolization, Therapeutic; Ethanol; Humans; Iohexol; Iopamidol; Ioxaglic Ac	1987
Comparison of two strengths of iohexol and iothalamate in urography. Urologic radiology, 1987, Volume: 9, Issue:1 Topics: Adult; Aged; Female; Humans; Iohexol; Iothalamate Meglumine; Kidney; Kidney Diseases; Male; Middle A	1987

iohexol and Kidney Diseases