Page last updated: 2024-10-29

iohexol and Ischemia

iohexol has been researched along with Ischemia in 26 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
" This study aimed to determine the effect of an HMG-CoA reductase inhibitor, simvastatin (Zocor), on renal function in rats after ischemia/reperfusion injury (I/R) with concomitant CyA treatment."7.72Simvastatin attenuates renal ischemia/reperfusion injury in rats administered cyclosporine A. ( Davis, NA; Inman, SR; Lukaszek, VA; Olson, KM, 2003)
" infusions of mannitol and iohexol were studied in untreated mice as well as in mice after temporary renal ischemia."7.68In vivo fluorescence microscopy of microcirculation in the renal cortex of mice. Part IV. Effects of mannitol and iohexol infusions after temporary renal ischemia. ( Hietala, SO; Högström, B; Rooth, P, 1993)
" This study aimed to determine the effect of an HMG-CoA reductase inhibitor, simvastatin (Zocor), on renal function in rats after ischemia/reperfusion injury (I/R) with concomitant CyA treatment."3.72Simvastatin attenuates renal ischemia/reperfusion injury in rats administered cyclosporine A. ( Davis, NA; Inman, SR; Lukaszek, VA; Olson, KM, 2003)
"The use of MRX-320 as an oral contrast agent with an intravenous bolus of iohexol at CT increased reader confidence for the diagnosis of intestinal ischemia and improved subjective measures of image quality."3.70Evaluation of an experimental low-attenuation gastrointestinal contrast agent for CT imaging of intestinal ischemia in an animal model. ( Chosy, SG; Krupinski, EA; Kuhlman, JE; Lee, FT; Spilde, JM; Yandow, DR, 1999)
"This study evaluates the use of iohexol as a radiographic diagnostic contrast agent in normal animals and those with experimental bowel ischemia and obstruction."3.67Use of iohexol in the radiographic diagnosis of ischemic bowel. ( Billmire, DF; Block, T; Cohen, M; Grosfeld, JL; Gunter, M; Schwartzentruber, DJ, 1986)
"Transient cortical blindness is a rare complication of angiographic contrast use."1.31Cortical blindness after subclavian arteriography. ( Boyes, LA; Tew, K, 2000)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's5 (19.23)18.2507
2000's9 (34.62)29.6817
2010's5 (19.23)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Patel, A1
Irani, FG1
Pua, U1
Tay, KH1
Chong, TT1
Leong, S1
Chan, ES1
Tan, GWL1
Burgmans, MC1
Zhuang, KD1
Quek, LHH1
Kwan, J1
Damodharan, K1
Gogna, A1
Tan, BP1
Too, CW1
Chan, SXJM1
Chng, SP1
Yuan, W1
Tan, BS1
Lourenco, PDM1
Rawski, R1
Mohammed, MF1
Khosa, F1
Nicolaou, S1
McLaughlin, P1
Lv, P1
Liu, J1
Wu, R1
Hou, P1
Hu, L1
Gao, J1
Potretzke, TA1
Brace, CL1
Lubner, MG1
Sampson, LA1
Willey, BJ1
Lee, FT2
Chang, WC1
Sun, Y1
Wu, EH1
Kim, SY1
Wang, ZJ1
Huang, GS1
Yeh, BM1
Blachar, A1
Barnes, S1
Adam, SZ1
Levy, G1
Weinstein, I1
Precel, R1
Federle, MP1
Sosna, J1
Gaggl, A1
Penka, B1
Schultes, G1
Kärcher, H1
Esplugas, E1
Cequier, A1
Gomez-Hospital, JA1
Del Blanco, BG1
Jara, F1
Spilde, JM1
Chosy, SG1
Krupinski, EA1
Kuhlman, JE1
Yandow, DR1
Kirkpatrick, ID1
Kroeker, MA1
Greenberg, HM1
Inman, SR1
Davis, NA1
Olson, KM1
Lukaszek, VA1
Bell, KW1
Heng, RC1
Atallah, J1
Chaitowitz, I1
Sheedy, SP1
Earnest, F1
Fletcher, JG1
Fidler, JL1
Hoskin, TL1
Möckel, M1
Radovic, M1
Kühnle, Y1
Combé, V1
Waigand, J1
Schröder, S1
Dietz, R1
Frei, U1
Eckardt, KU1
Wootton, SL1
Coley, BD1
Hilton, SV1
Edwards, DK1
Amberg, JR1
Mattrey, RF1
Högström, B1
Hietala, SO1
Rooth, P1
Savader, SJ1
Williams, GM1
Trerotola, SO1
Perler, BA1
Wang, MC1
Venbrux, AC1
Lund, GB1
Osterman, FA1
Linkous, MD1
Nelson, MT1
Mulvihill, SJ1
Goldberg, HI1
Boyes, LA1
Tew, K1
Wintersperger, BJ1
Huber, A1
Preissler, G1
Holzknecht, N1
Helmberger, T1
Petsch, R1
Billing, A1
Scheidler, J1
Reiser, M1
Stordahl, A4
Laerum, F2
Erpicum, P1
Davies, MR1
Schwartzentruber, DJ1
Billmire, DF1
Cohen, M1
Block, T1
Gunter, M1
Grosfeld, JL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Controlled Trial of MAGIcTouch - Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease[NCT06182397]368 participants (Anticipated)Interventional2024-01-15Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for iohexol and Ischemia

ArticleYear
Comparative tolerability of contrast media used for coronary interventions.
    Drug safety, 2002, Volume: 25, Issue:15

    Topics: Cardiovascular Diseases; Cardiovascular Surgical Procedures; Cardiovascular System; Clinical Trials

2002

Trials

1 trial available for iohexol and Ischemia

ArticleYear
Randomized Controlled Trial Comparing Drug-coated Balloon Angioplasty versus Conventional Balloon Angioplasty for Treating Below-the-Knee Arteries in Critical Limb Ischemia: The SINGA-PACLI Trial.
    Radiology, 2021, Volume: 300, Issue:3

    Topics: Angiography; Angioplasty, Balloon; Contrast Media; Double-Blind Method; Drug Delivery Systems; Femal

2021

Other Studies

24 other studies available for iohexol and Ischemia

ArticleYear
Dual-Energy CT Iodine Mapping and 40-keV Monoenergetic Applications in the Diagnosis of Acute Bowel Ischemia.
    AJR. American journal of roentgenology, 2018, Volume: 211, Issue:3

    Topics: Acute Disease; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Image Processing, Computer-A

2018
Use of non-linear image blending with dual-energy CT improves vascular visualization in abdominal angiography.
    Clinical radiology, 2014, Volume: 69, Issue:2

    Topics: Abdomen; Adult; Aged; Analysis of Variance; Angiography; Contrast Media; Female; Humans; Iohexol; Is

2014
Early small-bowel ischemia: dual-energy CT improves conspicuity compared with conventional CT in a swine model.
    Radiology, 2015, Volume: 275, Issue:1

    Topics: Animals; Contrast Media; Cross-Over Studies; Disease Models, Animal; Intestine, Small; Iohexol; Isch

2015
CT Findings for Detecting the Presence of Gangrenous Ischemia in Cholecystitis.
    AJR. American journal of roentgenology, 2016, Volume: 207, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Cholecystitis; Contrast Media; Diagnosis, Differe

2016
Radiologists' performance in the diagnosis of acute intestinal ischemia, using MDCT and specific CT findings, using a variety of CT protocols.
    Emergency radiology, 2011, Volume: 18, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Clinical Competence

2011
Assessment of perfusion of facial microvascular transplants and early detection of ischemia by perfusion-CT scan.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2002, Volume: 94, Issue:4

    Topics: Bone Transplantation; Carcinoma, Squamous Cell; Chi-Square Distribution; Contrast Media; Facial Neop

2002
Evaluation of an experimental low-attenuation gastrointestinal contrast agent for CT imaging of intestinal ischemia in an animal model.
    Academic radiology, 1999, Volume: 6, Issue:2

    Topics: Administration, Oral; Analysis of Variance; Animals; Contrast Media; Disease Models, Animal; Dogs; F

1999
Biphasic CT with mesenteric CT angiography in the evaluation of acute mesenteric ischemia: initial experience.
    Radiology, 2003, Volume: 229, Issue:1

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Angiography; Contrast Media; Female; Humans; Intestin

2003
Simvastatin attenuates renal ischemia/reperfusion injury in rats administered cyclosporine A.
    The American journal of the medical sciences, 2003, Volume: 326, Issue:3

    Topics: Analysis of Variance; Animals; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Glomerul

2003
Use of intra-arterial multi-detector row CT angiography for the evaluation of an ischaemic limb in a patient with renal impairment.
    Australasian radiology, 2006, Volume: 50, Issue:4

    Topics: Aged; Angiography, Digital Subtraction; Contraindications; Contrast Media; Female; Humans; Image Int

2006
CT of small-bowel ischemia associated with obstruction in emergency department patients: diagnostic performance evaluation.
    Radiology, 2006, Volume: 241, Issue:3

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Child; Child, P

2006
Acute renal haemodynamic effects of radiocontrast media in patients undergoing left ventricular and coronary angiography.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:5

    Topics: Acute Kidney Injury; Aged; Blood Flow Velocity; Contrast Media; Coronary Angiography; Creatinine; Fe

2008
Value of brominated fluorocarbons for the radiographic diagnosis of small-bowel obstruction: comparison with other contrast agents in rats.
    AJR. American journal of roentgenology, 1993, Volume: 161, Issue:2

    Topics: Absorption; Animals; Barium Sulfate; Contrast Media; Diatrizoate Meglumine; Female; Fluorocarbons; G

1993
In vivo fluorescence microscopy of microcirculation in the renal cortex of mice. Part IV. Effects of mannitol and iohexol infusions after temporary renal ischemia.
    Acta radiologica (Stockholm, Sweden : 1987), 1993, Volume: 34, Issue:5

    Topics: Animals; Female; Infusions, Intravenous; Iohexol; Ischemia; Kidney; Kidney Cortex; Mannitol; Mice; M

1993
Preoperative spinal artery localization and its relationship to postoperative neurologic complications.
    Radiology, 1993, Volume: 189, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Angiography; Angiography, Digital Subtraction; Aortic Aneurysm, Abdo

1993
Noninvasive method for the detection of bowel ischemia: computed tomography detection of absorbed iodinated contrast material.
    Academic radiology, 1994, Volume: 1, Issue:1

    Topics: Animals; Contrast Media; Intestine, Small; Iohexol; Ischemia; Male; Random Allocation; Rats; Time Fa

1994
Cortical blindness after subclavian arteriography.
    Australasian radiology, 2000, Volume: 44, Issue:3

    Topics: Angiography; Blindness, Cortical; Contrast Media; Graft Occlusion, Vascular; Humans; Injections, Int

2000
[MR angiography of the supraaortic vessels].
    Der Radiologe, 2000, Volume: 40, Issue:9

    Topics: Adult; Aged; Angiography, Digital Subtraction; Aorta, Thoracic; Arm; Carotid Arteries; Carotid Steno

2000
Urinary excretion of iohexol administered enterally in rats with intestinal ischaemia. A transmural and transperitoneal route of transport.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:6

    Topics: Animals; Intestinal Absorption; Intestine, Small; Iohexol; Ischemia; Male; Rats; Rats, Inbred Strain

1988
Comparison of water-soluble contrast media and barium in rats with small bowel obstruction or ischemia.
    Investigative radiology, 1988, Volume: 23 Suppl 1

    Topics: Animals; Barium Sulfate; Contrast Media; Diatrizoate; Intestinal Obstruction; Intestine, Small; Iohe

1988
Urinary excretion of enteral iohexol in rats with intestinal ischaemia. The influence of size of ischaemic area and duration of exposure to contrast medium.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:8

    Topics: Animals; Intestines; Iohexol; Ischemia; Male; Radiography; Rats; Rats, Inbred Strains; Time Factors

1988
Water-soluble contrast media compared with barium in enteric follow-through. Urinary excretion and radiographic efficacy in rats with intestinal ischemia.
    Investigative radiology, 1988, Volume: 23, Issue:6

    Topics: Animals; Barium Sulfate; Contrast Media; Diatrizoate Meglumine; Intestine, Small; Iohexol; Ioxaglic

1988
Use of Iohexol in the radiographic diagnosis of ischemic bowel.
    Journal of pediatric surgery, 1987, Volume: 22, Issue:5

    Topics: Child; Child, Preschool; Humans; Intestines; Iohexol; Ischemia; Radiography

1987
Use of iohexol in the radiographic diagnosis of ischemic bowel.
    Journal of pediatric surgery, 1986, Volume: 21, Issue:6

    Topics: Animals; Contrast Media; Diagnosis, Differential; Diatrizoate Meglumine; Disease Models, Animal; Dru

1986