iohexol has been researched along with Intervertebral Disc Displacement in 24 studies
Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.
Intervertebral Disc Displacement: An INTERVERTEBRAL DISC in which the NUCLEUS PULPOSUS has protruded through surrounding ANNULUS FIBROSUS. This occurs most frequently in the lower lumbar region.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Whether a history of headache or "early" versus "late" ambulation (no bed rest or bed rest for 24 h) influence the occurrence of headache after lumbar iohexol myelography was studied by blinded interviews in 158 consecutive patients referred for elective lumbar myelography (LM) because of suspected lumbar disc prolapse or spinal stenosis." | 7.68 | Headache after lumbar iohexol myelography: the influence of a history of headaches and early ambulation. ( Ahlgren, P; Hallam, DM; Jensen, GS; Sonne, NM, 1993) |
| "Two non-ionic contrast media, iohexol and metrizamide, were compared in a double-blind clinical trial which included 50 patients who underwent lumbar myelography for disc herniation or spinal stenosis." | 5.05 | Lumbar myelography with iohexol and metrizamide. A double-blind clinical trial. ( Ekholm, SE; Hindmarsh, T; Kido, DK; Sahler, L; Sands, M, 1984) |
| "Whether a history of headache or "early" versus "late" ambulation (no bed rest or bed rest for 24 h) influence the occurrence of headache after lumbar iohexol myelography was studied by blinded interviews in 158 consecutive patients referred for elective lumbar myelography (LM) because of suspected lumbar disc prolapse or spinal stenosis." | 3.68 | Headache after lumbar iohexol myelography: the influence of a history of headaches and early ambulation. ( Ahlgren, P; Hallam, DM; Jensen, GS; Sonne, NM, 1993) |
| "Discogenic low back pain is believed to result from the degeneration and disruption of outer fibers of the intervertebral disc annulus, leading to a cycle of persistent inflammation, damage to the disc matrix, and sensitization of developed annular nociceptors." | 1.37 | Percutaneous diode laser irradiation for lumbar discogenic pain: a clinical study. ( Ishihara, M; Iwatsuki, K; Moriwaki, T; Ohnishi, Y; Umegaki, M; Yoshimine, T; Yoshimura, K, 2011) |
| " The patients were questioned about adverse effects, and they underwent psychometric assessment and EEG-recordings: 11 had adverse effects, chiefly mild and exclusively transient, without sequelae." | 1.28 | Intracranial iohexol-distribution following cervical myelography, postmyelographic registration of adverse effects, psychometric assessment and electroencephalographic recording. ( Eriksen, FB; Madsen, HH; Olsen, NK; Svare, U; Zeeberg, I, 1990) |
| " Terminal elimination half-life was 4." | 1.27 | Pharmacokinetics and excretion of iohexol after lumbar myelography in man. ( Kido, DK; Palace, GP; Sahler, L; Shaw, DD; Stroshane, RM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (37.50) | 18.7374 |
| 1990's | 9 (37.50) | 18.2507 |
| 2000's | 3 (12.50) | 29.6817 |
| 2010's | 3 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, RS | 1 |
| Wu, JS | 1 |
| Lu, HD | 1 |
| Zhu, HG | 1 |
| Li, X | 1 |
| Dong, J | 1 |
| Yuan, FL | 1 |
| Friedman, MV | 1 |
| Park, A | 1 |
| Bumpass, D | 1 |
| Jennings, JW | 1 |
| Matava, MJ | 1 |
| Myung, JS | 1 |
| Lee, JW | 1 |
| Park, GW | 1 |
| Yeom, JS | 1 |
| Choi, JY | 1 |
| Hong, SH | 1 |
| Kang, HS | 1 |
| Iwatsuki, K | 1 |
| Yoshimine, T | 1 |
| Umegaki, M | 1 |
| Yoshimura, K | 1 |
| Ohnishi, Y | 1 |
| Ishihara, M | 1 |
| Moriwaki, T | 1 |
| Hindmarsh, T | 2 |
| Ekholm, SE | 1 |
| Kido, DK | 2 |
| Sahler, L | 2 |
| Sands, M | 1 |
| Cronqvist, SE | 1 |
| Holtås, SL | 1 |
| Laike, T | 1 |
| Ozolins, A | 1 |
| Nakstad, P | 2 |
| Aaserud, O | 2 |
| Sortland, O | 1 |
| Nyberg-Hansen, R | 2 |
| Ericson, K | 1 |
| Hannerz, J | 1 |
| Helgetveit, A | 1 |
| Ganes, T | 1 |
| Bach-Gansmo, T | 1 |
| Dullerud, R | 1 |
| Schellhas, KP | 1 |
| Pollei, SR | 1 |
| Dorwart, RH | 1 |
| Shinomiya, K | 1 |
| Nakao, K | 1 |
| Shindoh, S | 1 |
| Mochida, K | 1 |
| Furuya, K | 1 |
| Hallam, DM | 1 |
| Sonne, NM | 1 |
| Jensen, GS | 1 |
| Ahlgren, P | 1 |
| Carragee, EJ | 1 |
| Chen, Y | 1 |
| Tanner, CM | 1 |
| Truong, T | 1 |
| Lau, E | 1 |
| Brito, JL | 1 |
| Vad, VB | 1 |
| Bhat, AL | 1 |
| Lutz, GE | 1 |
| Cammisa, F | 1 |
| Tervonen, O | 1 |
| Lähde, S | 1 |
| Vanharanta, H | 1 |
| Olsen, NK | 2 |
| Madsen, HH | 2 |
| Eriksen, FB | 1 |
| Svare, U | 2 |
| Zeeberg, I | 2 |
| Sand, T | 1 |
| Myhr, G | 1 |
| Stovner, LJ | 1 |
| Dale, LG | 1 |
| Milette, PC | 1 |
| Raymond, J | 1 |
| Fontaine, S | 1 |
| Donaghy, M | 1 |
| Fletcher, NA | 1 |
| Schott, GD | 1 |
| Shaw, DD | 1 |
| Stroshane, RM | 1 |
| Palace, GP | 1 |
| Jia, LS | 1 |
| Pon, A | 1 |
| Seifert, J | 1 |
| Schlegel, KF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of the Efficacy Between Transforaminal Steroid Epidural Injection and Epidural Neuroplasty for the Treatment of Herniated Lumbar Disc：A Single Center, Controlled Clinical Trial[NCT03101033] | 92 participants (Actual) | Interventional | 2015-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at one-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 29.11 |
| Transforaminal Steroid Injection Group | 35.02 |
ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at six-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 30.52 |
| Transforaminal Steroid Injection Group | 46.39 |
ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: at three-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 28.93 |
| Transforaminal Steroid Injection Group | 39.82 |
ODI (Oswestry disability index) consists of 10 subscales, which evaluates pain intensity, and functional satus of personal care, lifting, walking, sitting, standing, sleeping, sex, social life, traveling. Each subscales range from 0 to 5, with the higher score indicating more severe functional damage. the ODI score ranges from 0 to 100. it equals the sum of all the subscales and divided by 50. If the patients answers 9 subscale questions, then the total sum should be divided by 45, and by this analogy. (NCT03101033)
Timeframe: before treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 53.85 |
| Transforaminal Steroid Injection Group | 57.84 |
VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at one-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 2.37 |
| Transforaminal Steroid Injection Group | 2.35 |
VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at six-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 2.81 |
| Transforaminal Steroid Injection Group | 4.06 |
VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: at three-month post-treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 2.19 |
| Transforaminal Steroid Injection Group | 3.25 |
VAS (Visual analogue scale), with the highest score of 10, representing the most severe pain one could experience, and the lowest score of 0, representing no pain at all. The higher score means more severe pain. (NCT03101033)
Timeframe: before treatment
| Intervention | units on a scale (Mean) |
|---|---|
| Epidural Neuroplasty Group | 5.63 |
| Transforaminal Steroid Injection Group | 5.92 |
4 trials available for iohexol and Intervertebral Disc Displacement
| Article | Year |
|---|---|
Lumbar myelography with iohexol and metrizamide. A double-blind clinical trial.
Topics: Adolescent; Adult; Aged; Contrast Media; Double-Blind Method; Drug Evaluation; Female; Headache; Hum | 1984 |
Psychic changes following myelography with metrizamide and iohexol. A comparative investigation with psychologic tests.
Topics: Cognition Disorders; Contrast Media; Double-Blind Method; Drug Evaluation; Female; Humans; Intervert | 1984 |
Provocative discography in patients after limited lumbar discectomy: A controlled, randomized study of pain response in symptomatic and asymptomatic subjects.
Topics: Adult; Case-Control Studies; Contrast Media; Diskectomy; Female; Humans; Injections, Spinal; Interve | 2000 |
Transforaminal epidural steroid injections in lumbosacral radiculopathy: a prospective randomized study.
Topics: Adult; Anesthetics, Local; Betamethasone; Contrast Media; Fluoroscopy; Follow-Up Studies; Hospitals, | 2002 |
20 other studies available for iohexol and Intervertebral Disc Displacement
| Article | Year |
|---|---|
A Radiographic Measurement of the Anterior Epidural Space at L
Topics: Adult; Contrast Media; Epidural Space; Female; Fluoroscopy; Humans; Intervertebral Disc Displacement | 2017 |
Percutaneous discal cyst rupture in a professional football player using sublaminar epidural injection for thecal sac displacement.
Topics: Adult; Anti-Inflammatory Agents; Contrast Media; Cysts; Dexamethasone; Football; Humans; Injections, | 2015 |
MR diskography and CT diskography with gadodiamide-iodinated contrast mixture for the diagnosis of foraminal impingement.
Topics: Adult; Aged; Cefazolin; Contrast Media; Drug Combinations; Female; Gadolinium DTPA; Humans; Image En | 2008 |
Percutaneous diode laser irradiation for lumbar discogenic pain: a clinical study.
Topics: Contrast Media; Disability Evaluation; Female; Humans; Intervertebral Disc Displacement; Iohexol; La | 2011 |
Functional lumbar myelography with iohexol.
Topics: Adult; Aged; Contrast Media; Drug Evaluation; Female; Headache; Humans; Intervertebral Disc Displace | 1983 |
Experience with iohexol in lumbar myelography.
Topics: Adult; Aged; Cerebrospinal Fluid; Contrast Media; Drug Evaluation; Electroencephalography; Female; H | 1983 |
Cervical myelography with iohexol.
Topics: Adult; Aged; Contrast Media; Drug Evaluation; Electroencephalography; Female; Headache; Humans; Inte | 1984 |
Percutaneous automated nucleotomy and imaging with CT, MR and diskography in lumbar disk herniation.
Topics: Diskectomy, Percutaneous; Evaluation Studies as Topic; Follow-Up Studies; Humans; Intervertebral Dis | 1995 |
Thoracic discography. A safe and reliable technique.
Topics: Adolescent; Adult; Evaluation Studies as Topic; Female; Humans; Intervertebral Disc; Intervertebral | 1994 |
Evaluation of cervical diskography in pain origin and provocation.
Topics: Adult; Aged; Atrophy; Cervical Vertebrae; Contrast Media; Epidural Space; Female; Humans; Interverte | 1993 |
Headache after lumbar iohexol myelography: the influence of a history of headaches and early ambulation.
Topics: Adolescent; Adult; Early Ambulation; Female; Headache; Humans; Intervertebral Disc Displacement; Ioh | 1993 |
Ultrasound diagnosis of lumbar disc degeneration. Comparison with computed tomography/discography.
Topics: Adult; Female; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Iohexol; Lumbar Verteb | 1991 |
Intracranial iohexol-distribution following cervical myelography, postmyelographic registration of adverse effects, psychometric assessment and electroencephalographic recording.
Topics: Adult; Aged; Cervical Vertebrae; Electroencephalography; Female; Humans; Intervertebral Disc Displac | 1990 |
Side effects after lumbar iohexol myelography. Relation to radiological diagnosis, sex and age.
Topics: Adult; Age Factors; Aged; Female; Headache; Humans; Intervertebral Disc Displacement; Iohexol; Lumbo | 1990 |
Comparison of high-resolution computed tomography with discography in the evaluation of lumbar disc herniations.
Topics: Adult; Contrast Media; Female; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Iohexo | 1990 |
[Intrathecal distribution of iohexol after cervical myelography].
Topics: Adult; Aged; Brain; Cervical Vertebrae; Female; Humans; Injections, Spinal; Intervertebral Disc Disp | 1990 |
Encephalopathy after iohexol myelography.
Topics: Brain Diseases; Humans; Intervertebral Disc Displacement; Iodobenzoates; Iohexol; Male; Middle Aged; | 1985 |
Pharmacokinetics and excretion of iohexol after lumbar myelography in man.
Topics: Adult; Aged; Back Pain; Cauda Equina; Contrast Media; Female; Half-Life; Humans; Intervertebral Disc | 1985 |
[Omnipaque myelography in diagnosis of lumbar spinal disorders].
Topics: Adolescent; Adult; Aged; Female; Humans; Intervertebral Disc Displacement; Iohexol; Male; Middle Age | 1988 |
[Significance of diskography and contrast medium/enzyme interaction].
Topics: Chymopapain; Extravasation of Diagnostic and Therapeutic Materials; Humans; Intervertebral Disc Chem | 1986 |