iohexol has been researched along with Heart Failure in 14 studies
Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this clinical trial is to compare iodixanol with iohexol for the incidence of contrast-induced nephropathy in patients with chronic heart failure with reduced ejection fraction who are currently undergoing coronary angiography or angioplasty." | 9.24 | Comparison of the nephrotoxic effects of iodixanol versus iohexol in patients with chronic heart failure undergoing coronary angiography or angioplasty. ( Ge, Z; Li, Y; Shi, P; Song, M; Song, T; Sun, M, 2017) |
| "To compare the performance of iohexol plasma clearance and creatinine-based renal function estimating equations in monitoring longitudinal renal function changes in chronic heart failure (CHF) patients, and to assess the effects of body composition on the equation performance." | 7.81 | Iohexol clearance is superior to creatinine-based renal function estimating equations in detecting short-term renal function decline in chronic heart failure. ( Anker, SD; Cvan Trobec, K; Kerec Kos, M; Lainscak, M; Macdougall, IC; Ponikowski, P; von Haehling, S, 2015) |
| "The aim of this clinical trial is to compare iodixanol with iohexol for the incidence of contrast-induced nephropathy in patients with chronic heart failure with reduced ejection fraction who are currently undergoing coronary angiography or angioplasty." | 5.24 | Comparison of the nephrotoxic effects of iodixanol versus iohexol in patients with chronic heart failure undergoing coronary angiography or angioplasty. ( Ge, Z; Li, Y; Shi, P; Song, M; Song, T; Sun, M, 2017) |
| "To compare the performance of iohexol plasma clearance and creatinine-based renal function estimating equations in monitoring longitudinal renal function changes in chronic heart failure (CHF) patients, and to assess the effects of body composition on the equation performance." | 3.81 | Iohexol clearance is superior to creatinine-based renal function estimating equations in detecting short-term renal function decline in chronic heart failure. ( Anker, SD; Cvan Trobec, K; Kerec Kos, M; Lainscak, M; Macdougall, IC; Ponikowski, P; von Haehling, S, 2015) |
| " Iohexol supplemented with electrolytes (iohexol + electrolytes = IPE), oxygenated IPE (IPE+O), Ringer acetate, and oxygenated Ringer acetate were injected into the left coronary artery." | 3.69 | Coronary arteriography with an oxygenated contrast medium: cardiac effects in dogs with and without acute ischemic heart failure. ( Jacobsen, EA; Pedersen, HK; Refsum, H, 1996) |
| "We investigated the cardiac effects of single and repeated contrast media injections in dogs with heart failure and compared the effects of iohexol with iohexol supplemented with electrolytes (30 mmol/l NaCl, 0." | 3.69 | Additive hemodynamic and electrophysiologic effects of repeated intracoronary contrast media injections in dogs with heart failure. ( Jacobsen, EA; Mortensen, E; Pedersen, HK; Refsum, H, 1995) |
| "The relative incidence of long-term adverse effects between low-osmolar contrast media (LOCM) and iso-osmolar contrast media (IOCM) after coronary angiography is still unclear." | 1.43 | Long-Term Adverse Effects of Low-Osmolar Compared With Iso-Osmolar Contrast Media After Coronary Angiography. ( Chang, D; Ju, S; Lu, CQ; Tang, A; Wang, YC; Zhang, SJ, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qian, G | 1 |
| Yang, YQ | 1 |
| Dong, W | 1 |
| Cao, F | 1 |
| Chen, YD | 1 |
| Song, T | 1 |
| Song, M | 1 |
| Ge, Z | 1 |
| Li, Y | 1 |
| Shi, P | 1 |
| Sun, M | 1 |
| Bakos, Z | 1 |
| Markstad, H | 1 |
| Ostenfeld, E | 1 |
| Carlsson, M | 1 |
| Roijer, A | 1 |
| Borgquist, R | 1 |
| Lin, KY | 1 |
| Furth, SL | 1 |
| Schwartz, GJ | 1 |
| Shaddy, RE | 1 |
| Ruebner, RL | 1 |
| Cvan Trobec, K | 1 |
| Kerec Kos, M | 1 |
| von Haehling, S | 1 |
| Anker, SD | 1 |
| Macdougall, IC | 1 |
| Ponikowski, P | 1 |
| Lainscak, M | 1 |
| Salmon-Gandonnière, C | 1 |
| Benz-de Bretagne, I | 1 |
| Mercier, E | 1 |
| Joret, A | 1 |
| Halimi, JM | 1 |
| Ehrmann, S | 1 |
| Barin-Le Guellec, C | 1 |
| Wang, YC | 1 |
| Tang, A | 1 |
| Chang, D | 1 |
| Lu, CQ | 1 |
| Zhang, SJ | 1 |
| Ju, S | 1 |
| Knackstedt, C | 1 |
| Mühlenbruch, G | 1 |
| Mischke, K | 1 |
| Schimpf, T | 1 |
| Spüntrup, E | 1 |
| Günther, RW | 1 |
| Sanli, B | 1 |
| Kelm, M | 1 |
| Schauerte, P | 1 |
| Mahnken, AH | 1 |
| Yu, H | 1 |
| Zhang, D | 1 |
| Haller, S | 1 |
| Kanjwal, K | 1 |
| Colyer, W | 1 |
| Brewster, P | 1 |
| Steffes, M | 1 |
| Shapiro, JI | 1 |
| Cooper, CJ | 1 |
| Stückle, CA | 1 |
| Kickuth, R | 1 |
| Kirchner, EM | 1 |
| Liermann, D | 1 |
| Kirchner, J | 1 |
| Pedersen, HK | 3 |
| Jacobsen, EA | 2 |
| Refsum, H | 2 |
| Mortensen, E | 1 |
| Elliott, C | 1 |
| Reger, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Body Composition Changes and Cachexia on Bisoprolol and Ramipril Pharmacokinetics and Renal Function Estimation in Patients With Chronic Heart Failure[NCT01829880] | 60 participants (Anticipated) | Observational | 2011-10-31 | Recruiting | |||
| Evaluation of Glomerular Filtration Rate Using Iohexol Plasma Clearance in Critically Ill Patients With Augmented Renal Creatinine Clearance[NCT04776486] | 90 participants (Anticipated) | Interventional | 2020-09-03 | Recruiting | |||
| A Prospective Randomized Multicenter Study Comparing the Safety and Efficacy of Renal Artery Stenting With/Without Distal Protection Device (AngioGuard) and With/Without the Use of a Platelet Aggregator Inhibitor (Abciximab-Reopro) (RESIST)[NCT00234585] | Phase 2 | 100 participants | Interventional | 2002-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for iohexol and Heart Failure
| Article | Year |
|---|---|
Comparison of Iodixanol and Iopromide in Patients With Renal Insufficiency and Congestive Heart Failure Undergoing Coronary Angiography by Hemodynamic Monitoring.
Topics: Contrast Media; Coronary Angiography; Female; Heart Failure; Hemodynamic Monitoring; Humans; Iohexol | 2017 |
Comparison of the nephrotoxic effects of iodixanol versus iohexol in patients with chronic heart failure undergoing coronary angiography or angioplasty.
Topics: Adult; Angioplasty, Balloon, Coronary; China; Contrast Media; Coronary Angiography; Double-Blind Met | 2017 |
Determinants of renal function in patients with renal artery stenosis.
Topics: Abciximab; Aged; Aged, 80 and over; Antibodies, Monoclonal; Creatinine; Cystatin C; Double-Blind Met | 2011 |
11 other studies available for iohexol and Heart Failure
| Article | Year |
|---|---|
Combined preoperative information using a bullseye plot from speckle tracking echocardiography, cardiac CT scan, and MRI scan: targeted left ventricular lead implantation in patients receiving cardiac resynchronization therapy.
Topics: Aged; Cardiac Resynchronization Therapy; Contrast Media; Echocardiography; Feasibility Studies; Fema | 2014 |
Renal function assessment in child and adolescent heart transplant recipients during routine cardiac catheterization.
Topics: Adolescent; Cardiac Catheterization; Child; Child, Preschool; Cohort Studies; Cross-Sectional Studie | 2014 |
Iohexol clearance is superior to creatinine-based renal function estimating equations in detecting short-term renal function decline in chronic heart failure.
Topics: Aged; Aged, 80 and over; Chronic Disease; Creatinine; Female; Glomerular Filtration Rate; Heart Fail | 2015 |
Iohexol clearance in unstable critically ill patients: a tool to assess glomerular filtration rate.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Creatinine; Critical Illness; Female; Glomerular Filtr | 2016 |
Long-Term Adverse Effects of Low-Osmolar Compared With Iso-Osmolar Contrast Media After Coronary Angiography.
Topics: Aged; Cause of Death; China; Contrast Media; Coronary Angiography; Female; Heart Failure; Humans; In | 2016 |
Imaging of the coronary venous system in patients with congestive heart failure: comparison of 16 slice MSCT and retrograde coronary sinus venography: comparative imaging of coronary venous system.
Topics: Aged; Contrast Media; Coronary Angiography; Coronary Sinus; Coronary Vessels; Female; Heart Failure; | 2008 |
[Observing the density increase curve after intravenous contrast medium administration using a bolus triggering system: a method for detection cardiovascular disorders?].
Topics: Absorptiometry, Photon; Aged; Aorta, Abdominal; Contrast Media; Drug Administration Schedule; Female | 2002 |
Electrolyte addition to nonionic contrast media. Cardiac effects during experimental coronary arteriography.
Topics: Animals; Anti-Arrhythmia Agents; Contrast Media; Coronary Angiography; Dogs; Electrolytes; Heart; He | 1996 |
Coronary arteriography with an oxygenated contrast medium: cardiac effects in dogs with and without acute ischemic heart failure.
Topics: Animals; Contrast Media; Coronary Angiography; Coronary Disease; Dogs; Electrolytes; Heart Failure; | 1996 |
Additive hemodynamic and electrophysiologic effects of repeated intracoronary contrast media injections in dogs with heart failure.
Topics: Animals; Contrast Media; Coronary Vessels; Dogs; Electrocardiography; Electrolytes; Heart Failure; H | 1995 |
Acute renal failure following low osmolality radiocontrast dye.
Topics: Acute Kidney Injury; Cardiac Catheterization; Female; Heart Failure; Heart Valve Diseases; Humans; I | 1988 |