Page last updated: 2024-10-29

iohexol and Heart Failure

iohexol has been researched along with Heart Failure in 14 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"The aim of this clinical trial is to compare iodixanol with iohexol for the incidence of contrast-induced nephropathy in patients with chronic heart failure with reduced ejection fraction who are currently undergoing coronary angiography or angioplasty."9.24Comparison of the nephrotoxic effects of iodixanol versus iohexol in patients with chronic heart failure undergoing coronary angiography or angioplasty. ( Ge, Z; Li, Y; Shi, P; Song, M; Song, T; Sun, M, 2017)
"To compare the performance of iohexol plasma clearance and creatinine-based renal function estimating equations in monitoring longitudinal renal function changes in chronic heart failure (CHF) patients, and to assess the effects of body composition on the equation performance."7.81Iohexol clearance is superior to creatinine-based renal function estimating equations in detecting short-term renal function decline in chronic heart failure. ( Anker, SD; Cvan Trobec, K; Kerec Kos, M; Lainscak, M; Macdougall, IC; Ponikowski, P; von Haehling, S, 2015)
"The aim of this clinical trial is to compare iodixanol with iohexol for the incidence of contrast-induced nephropathy in patients with chronic heart failure with reduced ejection fraction who are currently undergoing coronary angiography or angioplasty."5.24Comparison of the nephrotoxic effects of iodixanol versus iohexol in patients with chronic heart failure undergoing coronary angiography or angioplasty. ( Ge, Z; Li, Y; Shi, P; Song, M; Song, T; Sun, M, 2017)
"To compare the performance of iohexol plasma clearance and creatinine-based renal function estimating equations in monitoring longitudinal renal function changes in chronic heart failure (CHF) patients, and to assess the effects of body composition on the equation performance."3.81Iohexol clearance is superior to creatinine-based renal function estimating equations in detecting short-term renal function decline in chronic heart failure. ( Anker, SD; Cvan Trobec, K; Kerec Kos, M; Lainscak, M; Macdougall, IC; Ponikowski, P; von Haehling, S, 2015)
" Iohexol supplemented with electrolytes (iohexol + electrolytes = IPE), oxygenated IPE (IPE+O), Ringer acetate, and oxygenated Ringer acetate were injected into the left coronary artery."3.69Coronary arteriography with an oxygenated contrast medium: cardiac effects in dogs with and without acute ischemic heart failure. ( Jacobsen, EA; Pedersen, HK; Refsum, H, 1996)
"We investigated the cardiac effects of single and repeated contrast media injections in dogs with heart failure and compared the effects of iohexol with iohexol supplemented with electrolytes (30 mmol/l NaCl, 0."3.69Additive hemodynamic and electrophysiologic effects of repeated intracoronary contrast media injections in dogs with heart failure. ( Jacobsen, EA; Mortensen, E; Pedersen, HK; Refsum, H, 1995)
"The relative incidence of long-term adverse effects between low-osmolar contrast media (LOCM) and iso-osmolar contrast media (IOCM) after coronary angiography is still unclear."1.43Long-Term Adverse Effects of Low-Osmolar Compared With Iso-Osmolar Contrast Media After Coronary Angiography. ( Chang, D; Ju, S; Lu, CQ; Tang, A; Wang, YC; Zhang, SJ, 2016)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's3 (21.43)18.2507
2000's2 (14.29)29.6817
2010's8 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Qian, G1
Yang, YQ1
Dong, W1
Cao, F1
Chen, YD1
Song, T1
Song, M1
Ge, Z1
Li, Y1
Shi, P1
Sun, M1
Bakos, Z1
Markstad, H1
Ostenfeld, E1
Carlsson, M1
Roijer, A1
Borgquist, R1
Lin, KY1
Furth, SL1
Schwartz, GJ1
Shaddy, RE1
Ruebner, RL1
Cvan Trobec, K1
Kerec Kos, M1
von Haehling, S1
Anker, SD1
Macdougall, IC1
Ponikowski, P1
Lainscak, M1
Salmon-Gandonnière, C1
Benz-de Bretagne, I1
Mercier, E1
Joret, A1
Halimi, JM1
Ehrmann, S1
Barin-Le Guellec, C1
Wang, YC1
Tang, A1
Chang, D1
Lu, CQ1
Zhang, SJ1
Ju, S1
Knackstedt, C1
Mühlenbruch, G1
Mischke, K1
Schimpf, T1
Spüntrup, E1
Günther, RW1
Sanli, B1
Kelm, M1
Schauerte, P1
Mahnken, AH1
Yu, H1
Zhang, D1
Haller, S1
Kanjwal, K1
Colyer, W1
Brewster, P1
Steffes, M1
Shapiro, JI1
Cooper, CJ1
Stückle, CA1
Kickuth, R1
Kirchner, EM1
Liermann, D1
Kirchner, J1
Pedersen, HK3
Jacobsen, EA2
Refsum, H2
Mortensen, E1
Elliott, C1
Reger, M1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Body Composition Changes and Cachexia on Bisoprolol and Ramipril Pharmacokinetics and Renal Function Estimation in Patients With Chronic Heart Failure[NCT01829880]60 participants (Anticipated)Observational2011-10-31Recruiting
Evaluation of Glomerular Filtration Rate Using Iohexol Plasma Clearance in Critically Ill Patients With Augmented Renal Creatinine Clearance[NCT04776486]90 participants (Anticipated)Interventional2020-09-03Recruiting
A Prospective Randomized Multicenter Study Comparing the Safety and Efficacy of Renal Artery Stenting With/Without Distal Protection Device (AngioGuard) and With/Without the Use of a Platelet Aggregator Inhibitor (Abciximab-Reopro) (RESIST)[NCT00234585]Phase 2100 participants Interventional2002-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for iohexol and Heart Failure

ArticleYear
Comparison of Iodixanol and Iopromide in Patients With Renal Insufficiency and Congestive Heart Failure Undergoing Coronary Angiography by Hemodynamic Monitoring.
    Angiology, 2017, Volume: 68, Issue:10

    Topics: Contrast Media; Coronary Angiography; Female; Heart Failure; Hemodynamic Monitoring; Humans; Iohexol

2017
Comparison of the nephrotoxic effects of iodixanol versus iohexol in patients with chronic heart failure undergoing coronary angiography or angioplasty.
    Journal of interventional cardiology, 2017, Volume: 30, Issue:3

    Topics: Adult; Angioplasty, Balloon, Coronary; China; Contrast Media; Coronary Angiography; Double-Blind Met

2017
Determinants of renal function in patients with renal artery stenosis.
    Vascular medicine (London, England), 2011, Volume: 16, Issue:5

    Topics: Abciximab; Aged; Aged, 80 and over; Antibodies, Monoclonal; Creatinine; Cystatin C; Double-Blind Met

2011

Other Studies

11 other studies available for iohexol and Heart Failure

ArticleYear
Combined preoperative information using a bullseye plot from speckle tracking echocardiography, cardiac CT scan, and MRI scan: targeted left ventricular lead implantation in patients receiving cardiac resynchronization therapy.
    European heart journal. Cardiovascular Imaging, 2014, Volume: 15, Issue:5

    Topics: Aged; Cardiac Resynchronization Therapy; Contrast Media; Echocardiography; Feasibility Studies; Fema

2014
Renal function assessment in child and adolescent heart transplant recipients during routine cardiac catheterization.
    Pediatric transplantation, 2014, Volume: 18, Issue:7

    Topics: Adolescent; Cardiac Catheterization; Child; Child, Preschool; Cohort Studies; Cross-Sectional Studie

2014
Iohexol clearance is superior to creatinine-based renal function estimating equations in detecting short-term renal function decline in chronic heart failure.
    Croatian medical journal, 2015, Volume: 56, Issue:6

    Topics: Aged; Aged, 80 and over; Chronic Disease; Creatinine; Female; Glomerular Filtration Rate; Heart Fail

2015
Iohexol clearance in unstable critically ill patients: a tool to assess glomerular filtration rate.
    Clinical chemistry and laboratory medicine, 2016, Nov-01, Volume: 54, Issue:11

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Creatinine; Critical Illness; Female; Glomerular Filtr

2016
Long-Term Adverse Effects of Low-Osmolar Compared With Iso-Osmolar Contrast Media After Coronary Angiography.
    The American journal of cardiology, 2016, Oct-01, Volume: 118, Issue:7

    Topics: Aged; Cause of Death; China; Contrast Media; Coronary Angiography; Female; Heart Failure; Humans; In

2016
Imaging of the coronary venous system in patients with congestive heart failure: comparison of 16 slice MSCT and retrograde coronary sinus venography: comparative imaging of coronary venous system.
    The international journal of cardiovascular imaging, 2008, Volume: 24, Issue:8

    Topics: Aged; Contrast Media; Coronary Angiography; Coronary Sinus; Coronary Vessels; Female; Heart Failure;

2008
[Observing the density increase curve after intravenous contrast medium administration using a bolus triggering system: a method for detection cardiovascular disorders?].
    Der Radiologe, 2002, Volume: 42, Issue:6

    Topics: Absorptiometry, Photon; Aged; Aorta, Abdominal; Contrast Media; Drug Administration Schedule; Female

2002
Electrolyte addition to nonionic contrast media. Cardiac effects during experimental coronary arteriography.
    Acta radiologica. Supplementum, 1996, Volume: 405

    Topics: Animals; Anti-Arrhythmia Agents; Contrast Media; Coronary Angiography; Dogs; Electrolytes; Heart; He

1996
Coronary arteriography with an oxygenated contrast medium: cardiac effects in dogs with and without acute ischemic heart failure.
    Academic radiology, 1996, Volume: 3, Issue:6

    Topics: Animals; Contrast Media; Coronary Angiography; Coronary Disease; Dogs; Electrolytes; Heart Failure;

1996
Additive hemodynamic and electrophysiologic effects of repeated intracoronary contrast media injections in dogs with heart failure.
    Academic radiology, 1995, Volume: 2, Issue:11

    Topics: Animals; Contrast Media; Coronary Vessels; Dogs; Electrocardiography; Electrolytes; Heart Failure; H

1995
Acute renal failure following low osmolality radiocontrast dye.
    Clinical cardiology, 1988, Volume: 11, Issue:6

    Topics: Acute Kidney Injury; Cardiac Catheterization; Female; Heart Failure; Heart Valve Diseases; Humans; I

1988