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iohexol and Heart Diseases

iohexol has been researched along with Heart Diseases in 16 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.

Research Excerpts

ExcerptRelevanceReference
" The secondary endpoints are absolute and relative increases in sCr of at least 50%, thrombolysis in myocardial infarction (TIMI) perfusion grade, and major adverse cardiac events at 1, 6, and 12 months."2.75The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study. ( Angioli, P; Bolognese, L; Carrera, A; Ducci, K; Falsini, G; Grotti, S; Liistro, F; Limbruno, U; Picchi, A; Pierli, C, 2010)
"Gadolinium-based contrast agents can be used in diagnostic and interventional angiography, and are safe in recommended doses in patients with impaired renal function, but the image quality is usually unsatisfactory."2.72Safety of gadodiamide mixed with a small quantity of iohexol in patients with impaired renal function undergoing coronary angiography. ( Barcin, C; Isik, E; Iyisoy, A; Kose, S; Kursaklioglu, H; Tore, HF, 2006)
"This rare pulmonary embolism complication can be easily detected on multidetector computed tomography using a wider scan range."1.36Pulmonary embolism associated with inferior vena cava interruption: multidetector computed tomography findings. ( Chae, EJ; Hyun, DH; Kim, M; Lee, CW; Lee, HJ; Seo, JB; Song, JW, 2010)
"The incidence of renal failure (as a percentage of total reports) was approximately 3."1.30Reports on contrast media reactions: analysis of data from reports to the U.S. Food and Drug Administration. ( Berry, CC; Lasser, EC; Lyon, SG, 1997)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's3 (18.75)18.2507
2000's4 (25.00)29.6817
2010's8 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yeo, LLL1
Holmin, S1
Andersson, T1
Lundström, E1
Gopinathan, A1
Lim, EL1
Leong, BSH1
Kuan, WS1
Ting, E1
Tan, BYQ1
Eide, SE1
Tay, ELK1
McCullough, PA1
Todoran, TM1
Brilakis, ES1
Ryan, MP1
Gunnarsson, C1
Masuda, T1
Nakaura, T1
Funama, Y1
Sato, T1
Nitta, T1
Higaki, T1
Baba, Y1
Matsumoto, Y1
Imada, N1
Awai, K1
Inokuchi, G1
Yajima, D1
Hayakawa, M1
Motomura, A1
Chiba, F1
Torimitsu, S1
Makino, Y1
Iwase, H1
Treweeke, AT1
Maskrey, BH1
Hickson, K1
Miller, JH1
Leslie, SJ1
Megson, IL1
Bolognese, L1
Falsini, G1
Grotti, S1
Limbruno, U1
Liistro, F1
Carrera, A1
Angioli, P1
Picchi, A1
Ducci, K1
Pierli, C1
Hyun, DH1
Seo, JB1
Chae, EJ1
Lee, CW1
Lee, HJ1
Kim, M1
Song, JW1
Tsai, HY1
Chen, MC1
Tsai, IC1
Chen, CC1
Artunc, FH1
Fischer, IU1
Risler, T1
Erley, CM1
Niboshi, A1
Nishida, M1
Itoi, T1
Shiraishi, I1
Hamaoka, K1
Barcin, C1
Kursaklioglu, H1
Iyisoy, A1
Kose, S1
Tore, HF1
Isik, E1
Nyman, U1
Elmståhl, B1
Nilsson, M1
Mancini, GB1
Atwood, JE1
Bhargava, V1
Slutsky, RA1
Grover, M1
Higgins, CB1
Hill, JA1
Winniford, M1
Cohen, MB1
Van Fossen, DB1
Murphy, MJ1
Halpern, EF1
Ludbrook, PA1
Wexler, L1
Rudnick, MR1
Goldfarb, S1
Lasser, EC1
Lyon, SG1
Berry, CC1
Gare, M1
Haviv, YS1
Ben-Yehuda, A1
Rubinger, D1
Bdolah-Abram, T1
Fuchs, S1
Gat, O1
Popovtzer, MM1
Gotsman, MS1
Mosseri, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Contrast Media and Nephrotoxicity Following Coronary Revascularization by Primary Angioplasty for Acute Myocardial Infarction. The CONTRAST-AMI Study.[NCT00827788]Phase 4432 participants (Anticipated)Interventional2008-12-31Completed
Department of Geriatrics[NCT02575092]Phase 2/Phase 34,000 participants (Actual)Interventional2015-11-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for iohexol and Heart Diseases

ArticleYear
Iodixanol Has a Favourable Fibrinolytic Profile Compared to Iohexol in Cardiac Patients Undergoing Elective Angiography: A Double-Blind, Randomized, Parallel Group Study.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Aged; Angiography; Contrast Media; Double-Blind Method; Heart Diseases; Humans; Iohexol; Male; Middl

2016
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
Safety of gadodiamide mixed with a small quantity of iohexol in patients with impaired renal function undergoing coronary angiography.
    Heart and vessels, 2006, Volume: 21, Issue:3

    Topics: Aged; Azotemia; Comorbidity; Contrast Media; Coronary Angiography; Creatinine; Drug Combinations; Fe

2006
Multicenter trial of ionic versus nonionic contrast media for cardiac angiography. The Iohexol Cooperative Study.
    The American journal of cardiology, 1993, Oct-01, Volume: 72, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Angiocardiography; Cardiovascular Diseases; Contrast Media; Creatini

1993
The renal effect of low-dose dopamine in high-risk patients undergoing coronary angiography.
    Journal of the American College of Cardiology, 1999, Nov-15, Volume: 34, Issue:6

    Topics: Cardiotonic Agents; Contrast Media; Coronary Angiography; Creatinine; Diabetes Complications; Dopami

1999

Other Studies

11 other studies available for iohexol and Heart Diseases

ArticleYear
Nongated Cardiac Computed Tomographic Angiograms for Detection of Embolic Sources in Acute Ischemic Stroke.
    Stroke, 2017, Volume: 48, Issue:5

    Topics: Aged; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Atrial Appendage; Brain Ischemia; Compute

2017
Rate of major adverse renal or cardiac events with iohexol compared to other low osmolar contrast media during interventional cardiovascular procedures.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2019, 02-01, Volume: 93, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Cardiac Catheterization; Cerebrovas

2019
Effect of Patient Characteristics on Vessel Enhancement in Pediatric Chest Computed Tomography Angiography.
    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 2019, Volume: 70, Issue:2

    Topics: Age Factors; Aorta; Body Height; Body Surface Area; Body Weight; Cardiac Output; Computed Tomography

2019
The utility of postmortem computed tomography selective coronary angiography in parallel with autopsy.
    Forensic science, medicine, and pathology, 2013, Volume: 9, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Animals; Autopsy; Cause of Death; Contrast Media; Coronary Angiograp

2013
Pulmonary embolism associated with inferior vena cava interruption: multidetector computed tomography findings.
    Journal of thoracic imaging, 2010, Volume: 25, Issue:4

    Topics: Aged; Anticoagulants; Contrast Media; Diagnosis, Differential; Heart Diseases; Heparin; Humans; Iohe

2010
Partial ring artifact on cardiac CT: image presentation and clinical implication.
    The international journal of cardiovascular imaging, 2011, Volume: 27, Issue:5

    Topics: Aged; Artifacts; Contrast Media; Equipment Failure; Female; Heart Diseases; Humans; Iohexol; Predict

2011
Improved estimation of GFR by serum cystatin C in patients undergoing cardiac catheterization.
    International journal of cardiology, 2005, Jul-10, Volume: 102, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cardiac Catheterization; Contrast Media; Creatinine; Cys

2005
Renal function and cardiac angiography.
    Indian journal of pediatrics, 2006, Volume: 73, Issue:1

    Topics: Adolescent; Cardiac Catheterization; Child; Child, Preschool; Contrast Media; Cyanosis; Heart Diseas

2006
The dogma that gadolinium contrast media are less nephrotoxic than iodine agents for X-ray angiography is a misconception.
    Heart and vessels, 2007, Volume: 22, Issue:3

    Topics: Aged; Azotemia; Comorbidity; Contrast Media; Coronary Angiography; Creatinine; Drug Combinations; Fe

2007
Comparative effects of ionic and nonionic contrast materials on indexes of isovolumic contraction and relaxation in humans.
    The American journal of cardiology, 1984, Jan-01, Volume: 53, Issue:1

    Topics: Coronary Angiography; Diatrizoate; Diatrizoate Meglumine; Double-Blind Method; Heart Diseases; Hemod

1984
Reports on contrast media reactions: analysis of data from reports to the U.S. Food and Drug Administration.
    Radiology, 1997, Volume: 203, Issue:3

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Cause of Death;

1997