iohexol has been researched along with Glioma in 5 studies
Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The validated method has been successfully applied to a pharmacokinetic study of thermosensitive liposome-encapsulated lomustine containing iohexol and lomustine solution after intravenous administration to C6 glioma rats." | 7.77 | HPLC method validation for the quantification of lomustine to study pharmacokinetics of thermosensitive liposome-encapsulated lomustine containing iohexol for CT imaging in C6 glioma rats. ( Derendorf, H; Gao, J; Li, M; Liu, C; Yu, F; Zeng, Y; Zhang, B; Zhuang, L, 2011) |
| " The validated method has been successfully applied to a pharmacokinetic study of thermosensitive liposome-encapsulated lomustine containing iohexol and lomustine solution after intravenous administration to C6 glioma rats." | 3.77 | HPLC method validation for the quantification of lomustine to study pharmacokinetics of thermosensitive liposome-encapsulated lomustine containing iohexol for CT imaging in C6 glioma rats. ( Derendorf, H; Gao, J; Li, M; Liu, C; Yu, F; Zeng, Y; Zhang, B; Zhuang, L, 2011) |
| " Therefore, the pharmacokinetic properties of the CA possess a central role: iodinated x-ray CAs are small molecules that distribute rapidly within the extravascular extracellular space, whereas larger macromolecular compounds have a prolonged vascular phase and a restricted volume of distribution." | 1.39 | Dynamic contrast-enhanced computed tomography to assess antitumor treatment effects: comparison of two contrast agents with different pharmacokinetics. ( Grenacher, L; Jost, G; Pietsch, H, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shankar, JJ | 1 |
| Woulfe, J | 1 |
| Silva, VD | 1 |
| Nguyen, TB | 1 |
| Jost, G | 1 |
| Pietsch, H | 1 |
| Grenacher, L | 1 |
| Zhuang, L | 1 |
| Gao, J | 1 |
| Zeng, Y | 1 |
| Yu, F | 1 |
| Zhang, B | 1 |
| Li, M | 1 |
| Derendorf, H | 1 |
| Liu, C | 1 |
| Yeung, TP | 1 |
| Yartsev, S | 1 |
| Bauman, G | 1 |
| He, W | 1 |
| Fainardi, E | 1 |
| Lee, TY | 1 |
| Stiller, W | 1 |
| Kobayashi, M | 1 |
| Koike, K | 1 |
| Stampfl, U | 1 |
| Richter, GM | 1 |
| Semmler, W | 1 |
| Kiessling, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| CT Perfusion in the Prognostication of Cerebral High Grade Glioma[NCT01923922] | 100 participants (Anticipated) | Interventional | 2013-09-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for iohexol and Glioma
| Article | Year |
|---|---|
Evaluation of perfusion CT in grading and prognostication of high-grade gliomas at diagnosis: a pilot study.
Topics: Brain Neoplasms; Cerebral Angiography; Contrast Media; Female; Glioma; Humans; Iohexol; Male; Middle | 2013 |
Dynamic contrast-enhanced computed tomography to assess antitumor treatment effects: comparison of two contrast agents with different pharmacokinetics.
Topics: Algorithms; Animals; Antineoplastic Agents; Cell Line, Tumor; Contrast Media; Gadolinium; Glioma; Io | 2013 |
HPLC method validation for the quantification of lomustine to study pharmacokinetics of thermosensitive liposome-encapsulated lomustine containing iohexol for CT imaging in C6 glioma rats.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Calibration; Cell Line, Tumor; Ch | 2011 |
The effect of scan duration on the measurement of perfusion parameters in CT perfusion studies of brain tumors.
Topics: Brain Neoplasms; Cerebrovascular Circulation; Contrast Media; Female; Glioma; Humans; Iohexol; Male; | 2013 |
Initial Experience with a Novel Low-Dose Micro-CT System.
Topics: Animals; Coated Materials, Biocompatible; Contrast Media; Coronary Angiography; Coronary Restenosis; | 2007 |