Page last updated: 2024-10-29

iohexol and Glial Cell Tumors

iohexol has been researched along with Glial Cell Tumors in 5 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Research Excerpts

ExcerptRelevanceReference
" The validated method has been successfully applied to a pharmacokinetic study of thermosensitive liposome-encapsulated lomustine containing iohexol and lomustine solution after intravenous administration to C6 glioma rats."7.77HPLC method validation for the quantification of lomustine to study pharmacokinetics of thermosensitive liposome-encapsulated lomustine containing iohexol for CT imaging in C6 glioma rats. ( Derendorf, H; Gao, J; Li, M; Liu, C; Yu, F; Zeng, Y; Zhang, B; Zhuang, L, 2011)
" The validated method has been successfully applied to a pharmacokinetic study of thermosensitive liposome-encapsulated lomustine containing iohexol and lomustine solution after intravenous administration to C6 glioma rats."3.77HPLC method validation for the quantification of lomustine to study pharmacokinetics of thermosensitive liposome-encapsulated lomustine containing iohexol for CT imaging in C6 glioma rats. ( Derendorf, H; Gao, J; Li, M; Liu, C; Yu, F; Zeng, Y; Zhang, B; Zhuang, L, 2011)
" Therefore, the pharmacokinetic properties of the CA possess a central role: iodinated x-ray CAs are small molecules that distribute rapidly within the extravascular extracellular space, whereas larger macromolecular compounds have a prolonged vascular phase and a restricted volume of distribution."1.39Dynamic contrast-enhanced computed tomography to assess antitumor treatment effects: comparison of two contrast agents with different pharmacokinetics. ( Grenacher, L; Jost, G; Pietsch, H, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shankar, JJ1
Woulfe, J1
Silva, VD1
Nguyen, TB1
Jost, G1
Pietsch, H1
Grenacher, L1
Zhuang, L1
Gao, J1
Zeng, Y1
Yu, F1
Zhang, B1
Li, M1
Derendorf, H1
Liu, C1
Yeung, TP1
Yartsev, S1
Bauman, G1
He, W1
Fainardi, E1
Lee, TY1
Stiller, W1
Kobayashi, M1
Koike, K1
Stampfl, U1
Richter, GM1
Semmler, W1
Kiessling, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
CT Perfusion in the Prognostication of Cerebral High Grade Glioma[NCT01923922]100 participants (Anticipated)Interventional2013-09-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

5 other studies available for iohexol and Glial Cell Tumors

ArticleYear
Evaluation of perfusion CT in grading and prognostication of high-grade gliomas at diagnosis: a pilot study.
    AJR. American journal of roentgenology, 2013, Volume: 200, Issue:5

    Topics: Brain Neoplasms; Cerebral Angiography; Contrast Media; Female; Glioma; Humans; Iohexol; Male; Middle

2013
Dynamic contrast-enhanced computed tomography to assess antitumor treatment effects: comparison of two contrast agents with different pharmacokinetics.
    Investigative radiology, 2013, Volume: 48, Issue:10

    Topics: Algorithms; Animals; Antineoplastic Agents; Cell Line, Tumor; Contrast Media; Gadolinium; Glioma; Io

2013
HPLC method validation for the quantification of lomustine to study pharmacokinetics of thermosensitive liposome-encapsulated lomustine containing iohexol for CT imaging in C6 glioma rats.
    European journal of drug metabolism and pharmacokinetics, 2011, Volume: 36, Issue:2

    Topics: Animals; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Calibration; Cell Line, Tumor; Ch

2011
The effect of scan duration on the measurement of perfusion parameters in CT perfusion studies of brain tumors.
    Academic radiology, 2013, Volume: 20, Issue:1

    Topics: Brain Neoplasms; Cerebrovascular Circulation; Contrast Media; Female; Glioma; Humans; Iohexol; Male;

2013
Initial Experience with a Novel Low-Dose Micro-CT System.
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2007, Volume: 179, Issue:7

    Topics: Animals; Coated Materials, Biocompatible; Contrast Media; Coronary Angiography; Coronary Restenosis;

2007