iohexol has been researched along with Diabetic Nephropathies in 8 studies
Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Iohexol was tolerated well in patients with NRF and in patients with IRF without significant overall nephrotoxic effects." | 2.69 | Assessment of possible nephrotoxicity from iohexol in patients with normal and impaired renal function. ( Hietala, SO; Holmberg, G; Jakobsson, G; Lithner, F; Lundqvist, S; Skinningsrud, K; Stegmayr, B, 1998) |
| "Iohexol clearance was used as the "true GFR"." | 1.32 | Metabolic status in diabetes mellitus affects markers for glomerular filtration rate. ( Holmquist, P; Sjöblad, S; Torffvit, O, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gaspari, F | 1 |
| Ruggenenti, P | 1 |
| Porrini, E | 1 |
| Motterlini, N | 1 |
| Cannata, A | 1 |
| Carrara, F | 1 |
| Jiménez Sosa, A | 1 |
| Cella, C | 1 |
| Ferrari, S | 1 |
| Stucchi, N | 1 |
| Parvanova, A | 1 |
| Iliev, I | 1 |
| Trevisan, R | 1 |
| Bossi, A | 1 |
| Zaletel, J | 1 |
| Remuzzi, G | 1 |
| Shema-Didi, L | 1 |
| Kristal, B | 1 |
| Eizenberg, S | 1 |
| Marzuq, N | 1 |
| Sussan, M | 1 |
| Feldman-Idov, Y | 1 |
| Ofir, P | 1 |
| Atar, S | 1 |
| Holmquist, P | 1 |
| Torffvit, O | 2 |
| Sjöblad, S | 1 |
| Dussol, B | 1 |
| Morange, S | 1 |
| Loundoun, A | 1 |
| Auquier, P | 1 |
| Berland, Y | 1 |
| Spångberg-Viklund, B | 1 |
| Berglund, J | 1 |
| Nikonoff, T | 1 |
| Nyberg, P | 1 |
| Skau, T | 1 |
| Larsson, R | 1 |
| Apelqvist, J | 1 |
| Agardh, CD | 1 |
| Lundqvist, S | 1 |
| Holmberg, G | 1 |
| Jakobsson, G | 1 |
| Lithner, F | 1 |
| Skinningsrud, K | 1 |
| Stegmayr, B | 1 |
| Hietala, SO | 1 |
| Chowdhury, TA | 1 |
| Dyer, PH | 1 |
| Bartlett, WA | 1 |
| Legge, ES | 1 |
| Durbin, SM | 1 |
| Barnett, AH | 1 |
| Bain, SC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prediction of Excretion and Toxicity of High Dose Methotrexate in Children and Adolescents With Acute Lymphoblastic Leukemia and Lymphoma[NCT02133599] | 23 participants (Actual) | Interventional | 2014-07-24 | Completed | |||
| Efficacy of Oral Sodium Chloride vs iv Sodium Chloride in the Prevention of Contrast Nephropathy in Outpatients[NCT03476460] | Phase 2 | 269 participants (Actual) | Interventional | 2014-03-01 | Completed | ||
| Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease (ENRICH): A Randomized Controlled Trial[NCT05283512] | 254 participants (Anticipated) | Interventional | 2022-04-20 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for iohexol and Diabetic Nephropathies
| Article | Year |
|---|---|
Prevention of contrast-induced nephropathy with single bolus erythropoietin in patients with diabetic kidney disease: A randomized controlled trial.
Topics: Acetylcysteine; Acute Kidney Injury; Aged; Aged, 80 and over; Biomarkers; Contrast Media; Coronary A | 2016 |
A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients.
Topics: Administration, Oral; Aged; Contrast Media; Creatinine; Diabetic Nephropathies; Diuretics; Drug Syne | 2006 |
A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients.
Topics: Administration, Oral; Aged; Contrast Media; Creatinine; Diabetic Nephropathies; Diuretics; Drug Syne | 2006 |
A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients.
Topics: Administration, Oral; Aged; Contrast Media; Creatinine; Diabetic Nephropathies; Diuretics; Drug Syne | 2006 |
A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients.
Topics: Administration, Oral; Aged; Contrast Media; Creatinine; Diabetic Nephropathies; Diuretics; Drug Syne | 2006 |
Does prophylactic treatment with felodipine, a calcium antagonist, prevent low-osmolar contrast-induced renal dysfunction in hydrated diabetic and nondiabetic patients with normal or moderately reduced renal function?
Topics: Aged; Aged, 80 and over; Angiography; Calcium Channel Blockers; Contrast Media; Creatinine; Diabetes | 1996 |
Assessment of possible nephrotoxicity from iohexol in patients with normal and impaired renal function.
Topics: Adult; Aged; Contrast Media; Diabetic Nephropathies; Female; Humans; Iohexol; Kidney; Linear Models; | 1998 |
4 other studies available for iohexol and Diabetic Nephropathies
| Article | Year |
|---|---|
The GFR and GFR decline cannot be accurately estimated in type 2 diabetics.
Topics: Aged; Aged, 80 and over; Biomarkers; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; | 2013 |
Metabolic status in diabetes mellitus affects markers for glomerular filtration rate.
Topics: Acute Disease; Adolescent; Biomarkers; Child; Child, Preschool; Contrast Media; Creatinine; Cystatin | 2003 |
The effect of the non-ionic contrast medium iohexol on glomerular and tubular function in diabetic patients.
Topics: Age of Onset; Aged; Blood Glucose; Blood Pressure; Contrast Media; Creatinine; Diabetes Mellitus, Ty | 1996 |
Glomerular filtration rate determination in diabetic patients using iohexol clearance--comparison of single and multiple plasma sampling methods.
Topics: Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Humans; Injec | 1998 |