iohexol has been researched along with Diabetes Mellitus in 15 studies
Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In 562 evaluable patients (of 592 recruited), the contrast volume, presence of diabetes mellitus, mean baseline SCr and estimated glomerular filtration rate (eGFR) were comparable between the iopromide- and iodixanol-treated groups." | 5.16 | Renal tolerability of iopromide and iodixanol in 562 renally impaired patients undergoing cardiac catheterisation: the DIRECT study. ( Chen, Y; Fu, G; Gao, C; Gao, W; He, B; He, Q; Hu, S; Liu, H; Liu, S; Liu, Y; Qi, X; Qiu, C; Su, X; Wang, J; Wang, L; Wang, M; Yang, P; Zhao, R; Zheng, X; Zheng, Y; Zhou, S, 2012) |
| "5 mmol/L) and high-glucose (30 and 55 mmol/L) conditions for 24 hours to mimic hyperglycemia in diabetes mellitus and then were exposed to diatrizoate (40 and 80 mg I/mL) and iohexol (80, 120, 160 mg I/mL) for 2 hours." | 3.71 | Glucose alters the susceptibility of mesangial cells to contrast media. ( Shirota, K; Sugimoto, J; Wasaki, M, 2001) |
| "Sodium bicarbonate has been suggested as a possible strategy for prevention of contrast medium-induced nephropathy, a common cause of renal failure associated with prolonged hospitalization, increased health care costs, and substantial morbidity and mortality." | 2.73 | Sodium bicarbonate vs sodium chloride for the prevention of contrast medium-induced nephropathy in patients undergoing coronary angiography: a randomized trial. ( Aharonian, VJ; Brar, SS; Burchette, RJ; Desai, N; Jorgensen, MB; Kotlewski, A; Ree, M; Shah, AI; Shen, AY, 2008) |
| "In conclusion, diabetics have more atherosclerotic plaque burden and more severe coronary atherosclerosis than nondiabetics." | 1.37 | Comparison of atherosclerotic plaque by computed tomography angiography in patients with and without diabetes mellitus and with known or suspected coronary artery disease. ( Budoff, MJ; Cao, HL; Chen, Y; Gao, Y; Hou, ZH; Jiang, SL; Lu, B; Sun, ML; Yang, YJ; Yu, FF, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 7 (46.67) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Fu, EL | 1 |
| Levey, AS | 1 |
| Coresh, J | 1 |
| Elinder, CG | 1 |
| Rotmans, JI | 1 |
| Dekker, FW | 1 |
| Paik, JM | 1 |
| Barany, P | 1 |
| Grams, ME | 1 |
| Inker, LA | 1 |
| Carrero, JJ | 1 |
| Hudzik, B | 1 |
| Szkodziński, J | 1 |
| Korzonek-Szlacheta, I | 1 |
| Wilczek, K | 1 |
| Gierlotka, M | 1 |
| Lekston, A | 1 |
| Zubelewicz-Szkodzińska, B | 1 |
| Gąsior, M | 1 |
| Brar, SS | 1 |
| Shen, AY | 1 |
| Jorgensen, MB | 1 |
| Kotlewski, A | 1 |
| Aharonian, VJ | 1 |
| Desai, N | 1 |
| Ree, M | 1 |
| Shah, AI | 1 |
| Burchette, RJ | 1 |
| Gao, Y | 1 |
| Lu, B | 1 |
| Sun, ML | 1 |
| Hou, ZH | 1 |
| Yu, FF | 1 |
| Cao, HL | 1 |
| Chen, Y | 2 |
| Yang, YJ | 1 |
| Jiang, SL | 1 |
| Budoff, MJ | 1 |
| Hu, S | 1 |
| Liu, Y | 1 |
| Zhao, R | 1 |
| Wang, L | 1 |
| Fu, G | 1 |
| He, Q | 1 |
| Su, X | 1 |
| Zheng, Y | 1 |
| Qi, X | 1 |
| Liu, H | 1 |
| Wang, J | 1 |
| Gao, W | 1 |
| Wang, M | 1 |
| Liu, S | 1 |
| Zheng, X | 1 |
| He, B | 1 |
| Yang, P | 1 |
| Zhou, S | 1 |
| Gao, C | 1 |
| Qiu, C | 1 |
| Rouse, RL | 1 |
| Stewart, SR | 1 |
| Thompson, KL | 1 |
| Zhang, J | 1 |
| Aspelin, P | 1 |
| Aubry, P | 1 |
| Fransson, SG | 1 |
| Strasser, R | 1 |
| Willenbrock, R | 1 |
| Berg, KJ | 1 |
| Sandler, CM | 1 |
| Nicholson, T | 1 |
| Downes, M | 1 |
| Toprak, O | 1 |
| Cirit, M | 1 |
| Yesil, M | 1 |
| Bayata, S | 1 |
| Tanrisev, M | 1 |
| Varol, U | 1 |
| Ersoy, R | 1 |
| Esi, E | 1 |
| Bird, NJ | 1 |
| Peters, C | 1 |
| Michell, AR | 1 |
| Peters, AM | 1 |
| Nikonoff, T | 1 |
| Skau, T | 1 |
| Berglund, J | 1 |
| Nyberg, P | 1 |
| Spångberg-Viklund, B | 1 |
| Larsson, R | 1 |
| Houlihan, C | 1 |
| Jenkins, M | 1 |
| Osicka, T | 1 |
| Scott, A | 1 |
| Parkin, D | 1 |
| Jerums, G | 1 |
| Wasaki, M | 1 |
| Sugimoto, J | 1 |
| Shirota, K | 1 |
| Campbell, DR | 1 |
| Flemming, BK | 1 |
| Mason, WF | 1 |
| Jackson, SA | 1 |
| Hirsch, DJ | 1 |
| MacDonald, KJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Trial for Prevention of Contrast Nephropathy With Sodium Bicarbonate[NCT00312117] | Phase 3 | 300 participants | Interventional | 2006-01-31 | Completed | ||
| Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253] | Phase 3 | 400 participants (Anticipated) | Interventional | 2015-05-05 | Recruiting | ||
| Chinese People's Liberation Army General Hospital[NCT02718521] | 400 participants (Anticipated) | Interventional | 2016-03-31 | Active, not recruiting | |||
| A Randomized, Double-blinded Comparison of Iopromide and Iodixanol in Renally Impaired Patients Undergoing Cardiac Catheterization[NCT00926562] | Phase 4 | 592 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| Efficacy of Oral Sodium Chloride vs iv Sodium Chloride in the Prevention of Contrast Nephropathy in Outpatients[NCT03476460] | Phase 2 | 269 participants (Actual) | Interventional | 2014-03-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for iohexol and Diabetes Mellitus
| Article | Year |
|---|---|
Sodium bicarbonate vs sodium chloride for the prevention of contrast medium-induced nephropathy in patients undergoing coronary angiography: a randomized trial.
Topics: Aged; Contrast Media; Coronary Angiography; Diabetes Mellitus; Female; Glomerular Filtration Rate; H | 2008 |
Sodium bicarbonate vs sodium chloride for the prevention of contrast medium-induced nephropathy in patients undergoing coronary angiography: a randomized trial.
Topics: Aged; Contrast Media; Coronary Angiography; Diabetes Mellitus; Female; Glomerular Filtration Rate; H | 2008 |
Sodium bicarbonate vs sodium chloride for the prevention of contrast medium-induced nephropathy in patients undergoing coronary angiography: a randomized trial.
Topics: Aged; Contrast Media; Coronary Angiography; Diabetes Mellitus; Female; Glomerular Filtration Rate; H | 2008 |
Sodium bicarbonate vs sodium chloride for the prevention of contrast medium-induced nephropathy in patients undergoing coronary angiography: a randomized trial.
Topics: Aged; Contrast Media; Coronary Angiography; Diabetes Mellitus; Female; Glomerular Filtration Rate; H | 2008 |
Renal tolerability of iopromide and iodixanol in 562 renally impaired patients undergoing cardiac catheterisation: the DIRECT study.
Topics: Aged; Biomarkers; Cardiac Catheterization; China; Contrast Media; Coronary Angiography; Coronary Art | 2012 |
Renal tolerability of iopromide and iodixanol in 562 renally impaired patients undergoing cardiac catheterisation: the DIRECT study.
Topics: Aged; Biomarkers; Cardiac Catheterization; China; Contrast Media; Coronary Angiography; Coronary Art | 2012 |
Renal tolerability of iopromide and iodixanol in 562 renally impaired patients undergoing cardiac catheterisation: the DIRECT study.
Topics: Aged; Biomarkers; Cardiac Catheterization; China; Contrast Media; Coronary Angiography; Coronary Art | 2012 |
Renal tolerability of iopromide and iodixanol in 562 renally impaired patients undergoing cardiac catheterisation: the DIRECT study.
Topics: Aged; Biomarkers; Cardiac Catheterization; China; Contrast Media; Coronary Angiography; Coronary Art | 2012 |
Nephrotoxic effects in high-risk patients undergoing angiography.
Topics: Aged; Angiography; Contrast Media; Creatinine; Diabetes Mellitus; Double-Blind Method; Female; Human | 2003 |
A comparison of the plasma disappearance of iohexol and 99mTc-DTPA for the measurement of glomerular filtration rate (GFR) in diabetes.
Topics: Adult; Aged; Contrast Media; Diabetes Mellitus; Electrophoresis, Capillary; Female; Glomerular Filtr | 1999 |
A comparative study of the nephrotoxicity of iohexol, iopamidol and ioxaglate in peripheral angiography.
Topics: Acute Kidney Injury; Aged; Angiography; Creatinine; Diabetes Mellitus; Double-Blind Method; Female; | 1990 |
10 other studies available for iohexol and Diabetes Mellitus
| Article | Year |
|---|---|
Accuracy of GFR Estimating Equations in Patients with Discordances between Creatinine and Cystatin C-Based Estimations.
Topics: Adult; Cardiovascular Diseases; Creatinine; Cystatin C; Diabetes Mellitus; Glomerular Filtration Rat | 2023 |
Platelet-to-lymphocyte ratio predicts contrast-induced acute kidney injury in diabetic patients with ST-elevation myocardial infarction.
Topics: Acute Kidney Injury; Aged; Area Under Curve; Blood Platelets; Contrast Media; Coronary Angiography; | 2017 |
Comparison of atherosclerotic plaque by computed tomography angiography in patients with and without diabetes mellitus and with known or suspected coronary artery disease.
Topics: Contrast Media; Coronary Angiography; Coronary Stenosis; Diabetes Mellitus; Diabetes Mellitus, Type | 2011 |
Kidney injury biomarkers in hypertensive, diabetic, and nephropathy rat models treated with contrast media.
Topics: Animals; Biomarkers; Blood Urea Nitrogen; Contrast Media; Diabetes Mellitus; Hypertension; Iohexol; | 2013 |
Contrast-agent-induced acute renal dysfunction--is iodixanol the answer?
Topics: Contrast Media; Diabetes Mellitus; Humans; Iohexol; Kidney; Kidney Diseases; Triiodobenzoic Acids | 2003 |
Contrast nephrotoxicity and iso-osmolar contrast agents: implications of NEPHRIC.
Topics: Aged; Angiography, Digital Subtraction; Anti-Inflammatory Agents, Non-Steroidal; Contrast Media; Cre | 2003 |
Impact of diabetic and pre-diabetic state on development of contrast-induced nephropathy in patients with chronic kidney disease.
Topics: Blood Glucose; Contrast Media; Coronary Angiography; Coronary Disease; Creatinine; Diabetes Mellitus | 2007 |
Extracellular distribution volumes of hydrophilic solutes used to measure the glomerular filtration rate: comparison between chromium-51-EDTA and iohexol.
Topics: Adult; Aged; Algorithms; Contrast Media; Data Interpretation, Statistical; Diabetes Mellitus; Eating | 2007 |
Effects of femoral arteriography and low osmolar contrast agents on renal function.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Angiography; Contrast Media; Diabetes Mellitus; | 1993 |
Glucose alters the susceptibility of mesangial cells to contrast media.
Topics: Animals; Cell Survival; Contrast Media; Diabetes Mellitus; Diatrizoate; Glomerular Mesangium; Glucos | 2001 |