iohexol has been researched along with Delayed Hypersensitivity in 19 studies
Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This presented a management challenge as the patient had experienced 2 episodes of delayed anaphylaxis to Omnipaque (iohexol) RCM, and based on a literature review, there was no known or established precedent on a safe procedure in these situations." | 7.88 | Successful Graded Dose Challenge to Iodixanol Radiocontrast Media in a Patient With Delayed Anaphylaxis to Iohexol. ( Cohen, B; Edelman, D; Garg, K; Jariwala, S; Soffer, G; Toh, J, 2018) |
| " We report a case in which delayed hypersensitivity to iohexol, a nonionic intravenous contrast agent commonly used in excretory urography, resulted in a bi-phasic allergic response." | 4.79 | Delayed hypersensitivity reaction after infusion of nonionic intravenous contrast material for an excretory urogram: a case report and review of the literature. ( Resnick, MI; Seftel, AD; Stovsky, MD, 1995) |
| " This presented a management challenge as the patient had experienced 2 episodes of delayed anaphylaxis to Omnipaque (iohexol) RCM, and based on a literature review, there was no known or established precedent on a safe procedure in these situations." | 3.88 | Successful Graded Dose Challenge to Iodixanol Radiocontrast Media in a Patient With Delayed Anaphylaxis to Iohexol. ( Cohen, B; Edelman, D; Garg, K; Jariwala, S; Soffer, G; Toh, J, 2018) |
| "Cross-reactivity was assessed by skin testing and measurement of T-cell activation (CD69 upregulation) and proliferation ((3)H-thymidine uptake, 5,6-carboxyfluorescein diacetate succinimidyl ester staining) of PBMCs, T-cell lines, and T-cell clones of 2 patients with delayed hypersensitivity reactions to iohexol and iomeprol, respectively." | 3.74 | Cross-reactivity patterns of T cells specific for iodinated contrast media. ( Beeler, A; Bircher, AJ; Britschgi, M; Christiansen, C; Gerber, BO; Kanny, G; Keller, M; Lerch, M; Luethi, M; Pichler, WJ; Schmid, DA; Tache, V, 2007) |
| "To prospectively evaluate adverse events (AEs) in patients who underwent nonionic monomeric or dimeric contrast media-enhanced computed tomography (CT) and to compare these effects with AEs in patients who underwent unenhanced CT." | 2.72 | Adverse events after unenhanced and monomeric and dimeric contrast-enhanced CT: a prospective randomized controlled trial. ( Böhm, I; Hübner-Steiner, U; Kuhl, CK; Schild, HH; Speck, U, 2006) |
| "In Japan, drug eruptions to nonionic iodinated contrast media have been reported since the products appeared on the market in 1986." | 1.33 | Drug eruptions to contrast media in Japan. ( Akiyama, M; Iijima, M; Kato, A; Maibach, HI; Nakada, T, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 9 (47.37) | 29.6817 |
| 2010's | 6 (31.58) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soffer, G | 1 |
| Cohen, B | 1 |
| Toh, J | 1 |
| Edelman, D | 1 |
| Garg, K | 1 |
| Jariwala, S | 1 |
| Corbaux, C | 1 |
| Seneschal, J | 1 |
| Taïeb, A | 1 |
| Cornelis, F | 1 |
| Martinet, J | 1 |
| Milpied, B | 1 |
| Chuang, FR | 1 |
| Chen, TC | 1 |
| Wang, IK | 1 |
| Chuang, CH | 1 |
| Chang, HW | 1 |
| Ting-Yu Chiou, T | 1 |
| Cheng, YF | 1 |
| Lee, WC | 1 |
| Chen, WC | 1 |
| Yang, KD | 1 |
| Lee, CH | 1 |
| Loh, S | 1 |
| Bagheri, S | 1 |
| Katzberg, RW | 1 |
| Fung, MA | 1 |
| Li, CS | 1 |
| Hasdenteufel, F | 1 |
| Waton, J | 1 |
| Cordebar, V | 1 |
| Studer, M | 1 |
| Collignon, O | 1 |
| Luyasu, S | 1 |
| Beaudouin, E | 1 |
| Renaudin, JM | 1 |
| Morisset, M | 1 |
| Kanny, G | 2 |
| Barbaud, A | 1 |
| Gracia Bara, MT | 2 |
| Moreno, E | 2 |
| Laffond, E | 2 |
| Muñoz, FJ | 2 |
| Macias, E | 2 |
| Davila, I | 2 |
| Romano, A | 1 |
| Artesani, MC | 1 |
| Andriolo, M | 1 |
| Viola, M | 1 |
| Pettinato, R | 1 |
| Vecchioli-Scaldazza, A | 1 |
| Munechika, H | 3 |
| Hiramatsu, Y | 2 |
| Kudo, S | 2 |
| Sugimura, K | 2 |
| Hamada, C | 2 |
| Yamaguchi, K | 2 |
| Katayama, H | 2 |
| Shionoya, H | 1 |
| Sugihara, Y | 1 |
| Okano, K | 1 |
| Sagami, F | 1 |
| Mikami, T | 1 |
| Katayama, K | 1 |
| Nakada, T | 1 |
| Akiyama, M | 1 |
| Iijima, M | 1 |
| Kato, A | 1 |
| Maibach, HI | 1 |
| Schild, HH | 1 |
| Kuhl, CK | 1 |
| Hübner-Steiner, U | 1 |
| Böhm, I | 1 |
| Speck, U | 1 |
| Lerch, M | 1 |
| Keller, M | 1 |
| Britschgi, M | 1 |
| Tache, V | 1 |
| Schmid, DA | 1 |
| Beeler, A | 1 |
| Gerber, BO | 1 |
| Luethi, M | 1 |
| Bircher, AJ | 2 |
| Christiansen, C | 1 |
| Pichler, WJ | 1 |
| Stovsky, MD | 1 |
| Seftel, AD | 1 |
| Resnick, MI | 1 |
| Yasuda, R | 1 |
| Pedersen, SH | 1 |
| Svaland, MG | 1 |
| Reiss, AL | 1 |
| Andrew, E | 1 |
| Courvoisier, S | 1 |
| Sedano, E | 1 |
| Vega, JM | 1 |
| Rebollo, S | 1 |
| Callejo, A | 1 |
| Asensio, T | 1 |
| Almendros, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Clinical Trial to Investigate Adverse Reactions to MR and CT-examinations (Enhanced and Unenhanced)[NCT01132339] | 1,467 participants (Actual) | Observational | 2010-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for iohexol and Delayed Hypersensitivity
| Article | Year |
|---|---|
Delayed hypersensitivity reaction after infusion of nonionic intravenous contrast material for an excretory urogram: a case report and review of the literature.
Topics: Aged; Contrast Media; Drug Eruptions; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Iohe | 1995 |
Late allergy-like reactions following vascular administration of radiography contrast media.
Topics: Contrast Media; Drug Hypersensitivity; Europe; Humans; Hypersensitivity, Delayed; Hypersensitivity, | 1998 |
3 trials available for iohexol and Delayed Hypersensitivity
| Article | Year |
|---|---|
Comparison of iodixanol and iohexol in patients undergoing intravenous pyelography: a prospective controlled study.
Topics: Acute Kidney Injury; Adult; Aged; Contrast Media; Creatinine; Cytokines; Double-Blind Method; Drug E | 2009 |
Adverse events after unenhanced and monomeric and dimeric contrast-enhanced CT: a prospective randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Hypersensitivity, Delayed; Iohexol; | 2006 |
Late allergy-like reactions following vascular administration of radiography contrast media.
Topics: Contrast Media; Drug Hypersensitivity; Europe; Humans; Hypersensitivity, Delayed; Hypersensitivity, | 1998 |
15 other studies available for iohexol and Delayed Hypersensitivity
| Article | Year |
|---|---|
Successful Graded Dose Challenge to Iodixanol Radiocontrast Media in a Patient With Delayed Anaphylaxis to Iohexol.
Topics: Aged, 80 and over; Anaphylaxis; Angiography; Anti-Allergic Agents; Contrast Media; Drug Administrati | 2018 |
Delayed cutaneous hypersensitivity reactions to iodinated contrast media.
Topics: Aged; Contrast Media; Cross Reactions; Delayed Diagnosis; Drug Hypersensitivity; Humans; Hypersensit | 2017 |
Delayed adverse reaction to contrast-enhanced CT: a prospective single-center study comparison to control group without enhancement.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Chi-Square Distribution; Contrast Media; Femal | 2010 |
Delayed hypersensitivity reactions caused by iodixanol: an assessment of cross-reactivity in 22 patients.
Topics: Contrast Media; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; Iohexol; Iopamidol | 2011 |
Selection of contrast media in patients with delayed reactions should be based on challenge test results.
Topics: Contrast Media; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; Iohexol; Iopamidol | 2012 |
Reply: Selection of contrast media in patients with delayed reactions should be based on challenge test results.
Topics: Contrast Media; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; Iohexol; Iopamidol | 2012 |
Effective prophylactic protocol in delayed hypersensitivity to contrast media: report of a case involving lymphocyte transformation studies with different compounds.
Topics: Adult; Cerebral Angiography; Contrast Media; Cyclosporine; Drug Eruptions; Embolization, Therapeutic | 2002 |
A prospective survey of delayed adverse reactions to iohexol in urography and computed tomography.
Topics: Contrast Media; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; Injections, Intrav | 2003 |
Studies on experimental iodine allergy: 2. Iodinated protein antigens and their generation from inorganic and organic iodine-containing chemicals.
Topics: Adoptive Transfer; Albumins; Animals; Antigens; Antioxidants; Ascitic Fluid; Contrast Media; Disease | 2004 |
Drug eruptions to contrast media in Japan.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochon | 2006 |
Cross-reactivity patterns of T cells specific for iodinated contrast media.
Topics: Aged; Cell Line; Clone Cells; Contrast Media; Female; Humans; Hypersensitivity, Delayed; Iohexol; Io | 2007 |
Delayed adverse reactions to nonionic monomeric contrast-enhanced media.
Topics: Chi-Square Distribution; Contrast Media; Female; Humans; Hypersensitivity, Delayed; Iohexol; Iopamid | 1998 |
Delayed-type hypersensitivity to a nonionic, radiopaque contrast medium.
Topics: Angioplasty, Balloon, Coronary; Contrast Media; Humans; Hypersensitivity, Delayed; Iohexol; Iopamido | 1998 |
Delayed exanthema to nonionic contrast medium.
Topics: Aged; Contrast Media; Exanthema; Female; Humans; Hypersensitivity, Delayed; Iohexol; Male; Middle Ag | 2001 |
Delayed adverse reactions to nonionic contrast medium (iohexol) in IV use: multicentric study.
Topics: Contrast Media; Humans; Hypersensitivity, Delayed; Injections, Intravenous; Iohexol; Prevalence; Ris | 2002 |