Page last updated: 2024-10-29

iohexol and Brain Neoplasms

iohexol has been researched along with Brain Neoplasms in 23 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
" The validated method has been successfully applied to a pharmacokinetic study of thermosensitive liposome-encapsulated lomustine containing iohexol and lomustine solution after intravenous administration to C6 glioma rats."7.77HPLC method validation for the quantification of lomustine to study pharmacokinetics of thermosensitive liposome-encapsulated lomustine containing iohexol for CT imaging in C6 glioma rats. ( Derendorf, H; Gao, J; Li, M; Liu, C; Yu, F; Zeng, Y; Zhang, B; Zhuang, L, 2011)
" The validated method has been successfully applied to a pharmacokinetic study of thermosensitive liposome-encapsulated lomustine containing iohexol and lomustine solution after intravenous administration to C6 glioma rats."3.77HPLC method validation for the quantification of lomustine to study pharmacokinetics of thermosensitive liposome-encapsulated lomustine containing iohexol for CT imaging in C6 glioma rats. ( Derendorf, H; Gao, J; Li, M; Liu, C; Yu, F; Zeng, Y; Zhang, B; Zhuang, L, 2011)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19904 (17.39)18.7374
1990's7 (30.43)18.2507
2000's4 (17.39)29.6817
2010's8 (34.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zu, Z1
Li, H1
Jiang, X1
Gore, JC1
Chae, SY1
Suh, S1
Ryoo, I1
Park, A1
Noh, KJ1
Shim, H1
Seol, HY1
Shankar, JJ1
Woulfe, J1
Silva, VD1
Nguyen, TB1
Chen, T1
Guo, D1
Fang, Z1
Zhong, W1
Zhao, J1
Jiang, Y1
Zhuang, L1
Gao, J1
Zeng, Y1
Yu, F1
Zhang, B1
Li, M1
Derendorf, H1
Liu, C1
Zipp, L1
Schwartz, KM1
Hewer, E1
Yu, Y1
Stippich, C1
Slopis, JM1
Yeung, TP1
Yartsev, S1
Bauman, G1
He, W1
Fainardi, E1
Lee, TY2
Huang, WY1
Zhang, BY1
Geng, DY1
Zhang, J1
Roberts, HC1
Roberts, TP1
Dillon, WP1
Koh, TS2
Tan, CK1
Cheong, LH1
Lim, CC2
Hayakawa, K1
Shiozaki, T1
Yamamoto, A1
Kubo, S1
Osako, T1
Bisdas, S1
Yang, X1
Vogl, TJ1
Thron, A1
Ratzka, M1
Voigt, K1
Nadjmi, M1
Nakstad, P1
Sortland, O1
Aaserud, O1
Nicoletti, GF1
Barone, F1
Passanisi, M1
Mancuso, P1
Albanese, V1
Albert, FK1
Forsting, M1
Sartor, K1
Adams, HP1
Kunze, S1
Allen, ED1
Byrd, SE1
Darling, CF1
Tomita, T1
Wilczynski, MA1
Puskás, Z1
Schuierer, G1
Sighvatsson, V1
Ericson, K1
Tómasson, H1
Fujiwara, T1
Tanohata, K1
Onishi, T1
Matsui, K1
Grzyska, U1
Freitag, J1
Zeumer, H1
Langer, M1
Felix, R1
Behrends, B1
Eichstädt, H1
Fike, JR1
Cann, CE1
Turowski, K1
Norman, D1
Ax, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
CT Perfusion in the Prognostication of Cerebral High Grade Glioma[NCT01923922]100 participants (Anticipated)Interventional2013-09-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for iohexol and Brain Neoplasms

ArticleYear
Comparative study of vascular enhancement on post-contrast CT using three dosages of iodinated contrast media for the aim of detecting brain metastasis in patients with lung cancer.
    Radiation medicine, 2006, Volume: 24, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Brain Neoplasms; Contrast Media; Double-Blind Method; Female; Hum

2006
Iohexol and ioxaglate in cerebral angiography.
    Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. Erganzungsband, 1983, Volume: 118

    Topics: Adult; Aged; Brain Injuries; Brain Neoplasms; Cerebral Angiography; Cerebrovascular Disorders; Clini

1983
Iohexol compared to meglumine-Ca-metrizoate in common carotid angiography. A randomized double blind cross-over study in man.
    Neuroradiology, 1983, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Aged; Brain Diseases; Brain Neoplasms; Cerebral Angiography; Contrast Media; Doub

1983
Early postoperative magnetic resonance imaging after resection of malignant glioma: objective evaluation of residual tumor and its influence on regrowth and prognosis.
    Neurosurgery, 1994, Volume: 34, Issue:1

    Topics: Brain Neoplasms; Combined Modality Therapy; Contrast Media; Cranial Irradiation; Female; Follow-Up S

1994

Other Studies

19 other studies available for iohexol and Brain Neoplasms

ArticleYear
Spin-lock imaging of exogenous exchange-based contrast agents to assess tissue pH.
    Magnetic resonance in medicine, 2018, Volume: 79, Issue:1

    Topics: Animals; Brain; Brain Neoplasms; Contrast Media; Glioblastoma; Hydrogen-Ion Concentration; Iohexol;

2018
A semi-automated volumetric software for segmentation and perfusion parameter quantification of brain tumors using 320-row multidetector computed tomography: a validation study.
    Neuroradiology, 2017, Volume: 59, Issue:5

    Topics: Adult; Aged; Algorithms; Blood Volume; Brain Neoplasms; Contrast Media; Female; Humans; Iohexol; Mal

2017
Evaluation of perfusion CT in grading and prognostication of high-grade gliomas at diagnosis: a pilot study.
    AJR. American journal of roentgenology, 2013, Volume: 200, Issue:5

    Topics: Brain Neoplasms; Cerebral Angiography; Contrast Media; Female; Glioma; Humans; Iohexol; Male; Middle

2013
Preliminary study of whole-brain CT perfusion imaging in patients with intracranial tumours adjacent to large blood vessels.
    Clinical radiology, 2014, Volume: 69, Issue:1

    Topics: Adult; Aged; Blood Flow Velocity; Blood Volume; Brain Neoplasms; Cerebral Angiography; Cerebrovascul

2014
HPLC method validation for the quantification of lomustine to study pharmacokinetics of thermosensitive liposome-encapsulated lomustine containing iohexol for CT imaging in C6 glioma rats.
    European journal of drug metabolism and pharmacokinetics, 2011, Volume: 36, Issue:2

    Topics: Animals; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Calibration; Cell Line, Tumor; Ch

2011
Magnetic resonance imaging and computed tomography findings in pediatric giant cell glioblastoma.
    Clinical neuroradiology, 2012, Volume: 22, Issue:4

    Topics: Biomarkers, Tumor; Biopsy; Brain Neoplasms; Cerebral Ventricles; Child; Contrast Media; Diffusion Ma

2012
The effect of scan duration on the measurement of perfusion parameters in CT perfusion studies of brain tumors.
    Academic radiology, 2013, Volume: 20, Issue:1

    Topics: Brain Neoplasms; Cerebrovascular Circulation; Contrast Media; Female; Glioma; Humans; Iohexol; Male;

2013
Computed tomography and magnetic resonance features of extraventricular neurocytoma: a study of eight cases.
    Clinical radiology, 2013, Volume: 68, Issue:4

    Topics: Adolescent; Adult; Age Distribution; Brain; Brain Mapping; Brain Neoplasms; Calcinosis; Child; Contr

2013
Dynamic contrast-enhanced computed tomography (CT) for quantitative estimation of microvascular permeability in human brain tumors.
    Academic radiology, 2002, Volume: 9 Suppl 2

    Topics: Adenocarcinoma; Aged; Blood Volume; Brain Neoplasms; Capillary Permeability; Contrast Media; Female;

2002
Cerebral perfusion mapping using a robust and efficient method for deconvolution analysis of dynamic contrast-enhanced images.
    NeuroImage, 2006, Aug-15, Volume: 32, Issue:2

    Topics: Adenoma; Aged; Artifacts; Blood Flow Velocity; Blood Volume; Brain; Brain Neoplasms; Contrast Media;

2006
Delineation and segmentation of cerebral tumors by mapping blood-brain barrier disruption with dynamic contrast-enhanced CT and tracer kinetics modeling-a feasibility study.
    European radiology, 2008, Volume: 18, Issue:1

    Topics: Blood Volume; Blood-Brain Barrier; Brain Neoplasms; Cerebrovascular Circulation; Contrast Media; Fea

2008
Linear contrast enhancement at the operative site on early post-operative CT after removal of brain tumors.
    Journal of neurosurgical sciences, 1994, Volume: 38, Issue:2

    Topics: Adolescent; Adult; Aged; Astrocytoma; Brain; Brain Neoplasms; Cerebellar Neoplasms; Combined Modalit

1994
The clinical and radiological evaluation of primary brain neoplasms in children, Part II: Radiological evaluation.
    Journal of the National Medical Association, 1993, Volume: 85, Issue:7

    Topics: Brain; Brain Neoplasms; Cerebral Angiography; Child; Child, Preschool; Gadolinium; Humans; Infant; I

1993
[Determination of blood circulation time for optimizing contrast medium administration in CT angiography].
    Der Radiologe, 1996, Volume: 36, Issue:9

    Topics: Adult; Aged; Blood Flow Velocity; Brain; Brain Neoplasms; Carotid Stenosis; Cerebral Angiography; Co

1996
Optimising contrast-enhanced cranial CT for detection of brain metastases.
    Acta radiologica (Stockholm, Sweden : 1987), 1998, Volume: 39, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Contrast Media; Follow-Up Studies; Humans; Injectio

1998
Extravasation of contrast medium into the subdural space during cavernous sinus venography: a rare complication.
    Neuroradiology, 1992, Volume: 34, Issue:4

    Topics: Brain Neoplasms; Cavernous Sinus; Cerebral Angiography; Extravasation of Diagnostic and Therapeutic

1992
Selective cerebral intraarterial DSA. Complication rate and control of risk factors.
    Neuroradiology, 1990, Volume: 32, Issue:4

    Topics: Adult; Aged; Angiography, Digital Subtraction; Brain Neoplasms; Cerebral Angiography; Cerebrovascula

1990
[Use of nonionic contrast media in computerized tomography].
    Digitale Bilddiagnostik, 1987, Volume: 7, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Brain Diseases; Brain Neoplasms; Female; Humans; Iohexol; Male; Midd

1987
Contrast enhancement of brain tumors and irradiated normal brain: a comparison of iohexol and iothalamate.
    Neuroradiology, 1986, Volume: 28, Issue:1

    Topics: Animals; Brain; Brain Neoplasms; Dogs; Ependymoma; Iodine Radioisotopes; Iodobenzoates; Iohexol; Iot

1986