Page last updated: 2024-10-29

iohexol and Benign Neoplasms

iohexol has been researched along with Benign Neoplasms in 29 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Research Excerpts

ExcerptRelevanceReference
"In children and young adults with haemato-oncological disease and infection, renal function is best described by iohexol clearance from three-compartment pharmacokinetic model, while eGFR equations and single- and two-point mGFR formulas overestimate iGFR."8.12Glomerular filtration rate in children and young adults with haemato-oncological disease and infection is best described by three-compartment iohexol model. ( Karu, M; Kõrgvee, LT; Lass, J; Lutsar, I; Noortoots, A; Saks, K; Soeorg, H, 2022)
"In children and young adults with haemato-oncological disease and infection, renal function is best described by iohexol clearance from three-compartment pharmacokinetic model, while eGFR equations and single- and two-point mGFR formulas overestimate iGFR."4.12Glomerular filtration rate in children and young adults with haemato-oncological disease and infection is best described by three-compartment iohexol model. ( Karu, M; Kõrgvee, LT; Lass, J; Lutsar, I; Noortoots, A; Saks, K; Soeorg, H, 2022)
"Sixty patients with different malignant tumors were randomized into 4 different PET/CT protocols."2.72Optimized contrast-enhanced CT protocols for diagnostic whole-body 18F-FDG PET/CT: technical aspects of single-phase versus multiphase CT imaging. ( Aschoff, P; Bares, R; Beyer, T; Brechtel, K; Claussen, CD; Eschmann, SM; Klein, M; Mueller, M; Pfannenberg, AC; Vogel, M, 2006)
"We recommend that patients with cancer be implanted with a high-pressure resistant central venous catheter and receive effective measures to timely detect and reduce extravasation."1.91Contrast media extravasation injury: a prospective observational cohort study. ( Guan, H; He, L; Liu, W; Qiu, Y; Tang, H; Wang, C; Wang, P; Wang, X; Zhu, H, 2023)
"27% patients had colon cancer, 18% lung cancer."1.42Contrast enhanced chest-MDCT in oncologic patients. Prospective evaluation of the prevalence of incidental pulmonary embolism and added value of thin reconstructions. ( Colombo, B; Cornalba, G; Flor, N; Lombardi, MA; Luciani, A; Tresoldi, S, 2015)
"An elevated initial GFR in a child with cancer, which normalizes after chemotherapy may indicate chemotherapy-induced decreased renal function, but can be due to normalization of an initially high GFR."1.37Hyperfiltration evaluated by glomerular filtration rate at diagnosis in children with cancer. ( Hjorth, L; Karpman, D; Wiebe, T, 2011)
"VCT shows the vessel architecture of tumors and animals with greater detail and plasticity than has previously been achieved, and is superior to contrast-enhanced magnetic resonance (MR) angiography."1.32Volumetric computed tomography (VCT): a new technology for noninvasive, high-resolution monitoring of tumor angiogenesis. ( Bock, M; Fink, C; Fusenig, NE; Greschus, S; Kiessling, F; Lichy, MP; Moll, J; Mueller, MM; Semmler, W; Traupe, H; Vosseler, S, 2004)
"Iohexol clearance is an accepted, but time-consuming assay for the measurement of glomerular filtration rate (GFR)."1.31Correct evaluation of renal glomerular filtration rate requires clearance assays. ( Hjorth, L; Karpman, D; Wiebe, T, 2002)
"Iomeprol 400 was the strongest inhibitor and Gadopenteic acid the weakest inhibitor for each IRMA of the contrast agents employed."1.30In vitro effect of contrast agents during immunoradiometric assay for tumour-associated antigens. ( Endo, K; Fukushima, Y; Higuchi, T; Hirano, T; Inoue, T; Oriuchi, N; Tomiyoshi, K; Watanabe, N; Yukihiro, M, 1998)
"Of the 81 inpatients with cancer, seven (9%) had unsuspected PE."1.30Unsuspected pulmonary embolism: prospective detection on routine helical CT scans. ( Gosselin, MV; Huang, J; Leung, AN; Rizk, NW; Rubin, GD, 1998)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's2 (6.90)18.2507
2000's9 (31.03)29.6817
2010's15 (51.72)24.3611
2020's2 (6.90)2.80

Authors

AuthorsStudies
Soeorg, H1
Noortoots, A1
Karu, M1
Saks, K1
Lass, J1
Lutsar, I1
Kõrgvee, LT1
Liu, W1
Wang, P1
Zhu, H1
Tang, H1
Guan, H1
Wang, X1
Wang, C1
Qiu, Y1
He, L1
Terrenato, I1
Sperati, F1
Musicco, F1
Pozzi, AF1
di Turi, A1
Caterino, M1
de Lutio di Castelguidone, E1
Setola, SV1
Bellomi, M1
Neumaier, CE1
Conti, L1
Cigliana, G1
Merola, R1
Antenucci, A1
Orlandi, G1
Giordano, A1
Barba, M1
Canitano, S1
Rossi, F1
Körner, M1
Suárez, J1
Carozzi, G1
Meier, VS1
Roos, M1
Rohrer Bley, C1
Nagayama, Y1
Nakaura, T1
Oda, S1
Tsuji, A1
Urata, J1
Furusawa, M1
Tanoue, S1
Utsunomiya, D1
Yamashita, Y1
Wang, S1
Wang, H1
Song, C1
Li, Z1
Wang, Z1
Xu, H1
Yu, W1
Peng, C1
Li, M1
Chen, Z1
Katsoulakis, E1
Solomon, SB1
Maybody, M1
Housman, D1
Niyazov, G1
Riaz, N1
Lovelock, M1
Spratt, DE1
Erinjeri, JP1
Thornton, RH1
Yamada, Y1
Verburg, FA2
Apitzsch, J1
Lensing, C1
Kuhl, CK2
Pietsch, H2
Mottaghy, FM2
Behrendt, FF2
Cicin, I1
Erdogan, B1
Gulsen, E1
Uzunoglu, S1
Sut, N1
Turkmen, E1
Kodaz, H1
Ustundag, S1
Giglio, D1
Tresoldi, S1
Flor, N1
Luciani, A1
Lombardi, MA1
Colombo, B1
Cornalba, G1
Scialpi, M1
Palumbo, I1
Gravante, S1
Buresta, T1
D'Andrea, A1
Pierotti, L1
Palumbo, B1
Sun, JS1
Park, KJ1
Kang, DK1
Hjorth, L2
Wiebe, T2
Karpman, D2
Lee, JH1
Kim, J1
Moon, HJ1
Cho, A1
Yun, M1
Lee, JD1
Kang, WJ1
Rebière, M1
Palmowski, M1
Krohn, T1
Messiou, C1
Orton, M1
Ang, JE1
Collins, DJ1
Morgan, VA1
Mears, D1
Castellano, I1
Papadatos-Pastos, D1
Brunetto, A1
Tunariu, N1
Mann, H1
Tessier, J1
Young, H1
Ghiorghiu, D1
Marley, S1
Kaye, SB1
deBono, JS1
Leach, MO1
deSouza, NM1
Antoch, G1
Freudenberg, LS1
Egelhof, T1
Stattaus, J1
Jentzen, W1
Debatin, JF1
Bockisch, A1
Kiessling, F1
Greschus, S1
Lichy, MP1
Bock, M1
Fink, C1
Vosseler, S1
Moll, J1
Mueller, MM1
Fusenig, NE1
Traupe, H1
Semmler, W1
Brechtel, K1
Klein, M1
Vogel, M1
Mueller, M1
Aschoff, P1
Beyer, T1
Eschmann, SM1
Bares, R1
Claussen, CD1
Pfannenberg, AC1
Vogel, WV1
van Dalen, JA1
Oyen, WJ1
Bird, NJ1
Peters, C1
Michell, AR1
Peters, AM1
Purcell, DD1
Coakley, FV1
Franc, BL1
Hawkins, RA1
Boddington, SE1
Yeh, BM1
King, V1
Vaze, AA1
Moskowitz, CS1
Smith, LJ1
Ginsberg, MS1
Watanabe, N1
Oriuchi, N1
Higuchi, T1
Yukihiro, M1
Fukushima, Y1
Tomiyoshi, K1
Hirano, T1
Inoue, T1
Endo, K1
Gosselin, MV1
Rubin, GD1
Leung, AN1
Huang, J1
Rizk, NW1
Wisner, ER1
Weichert, JP1
Longino, MA1
Counsell, RE1
Weisbrode, SE1
Sjøgren, P1
Gefke, K1
Banning, AM1
Parslov, M1
Overgaard Olsen, LB1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Exploratory Open-Label, Non-randomised, Single Centre Methodology Study Comparing DCE-CT and DCE-MRI as Markers of Changes in Vascular Activity Mediated by a Positive Control Agent [Cediranib (Recentin™; AZD2171), a Potent Inhibitor of VEGF-driven Angioge[NCT00748891]Phase 135 participants (Anticipated)Interventional2008-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for iohexol and Benign Neoplasms

ArticleYear
Iodixanol versus iopromide in cancer patients: Evidence from a randomized clinical trial.
    Journal of cellular physiology, 2018, Volume: 233, Issue:3

    Topics: Adolescent; Adult; Aged; Contrast Media; Female; Glomerular Filtration Rate; Humans; Iohexol; Italy;

2018
Body surface area adapted iopromide 300 mg/ml versus 370 mg/ml contrast medium injection protocol: influence on quantitative and clinical assessment in combined PET/CT.
    European journal of radiology, 2013, Volume: 82, Issue:12

    Topics: Algorithms; Body Surface Area; Contrast Media; Dose-Response Relationship, Drug; Female; Humans; Ima

2013
Multiphase CT scanning and different intravenous contrast media concentrations in combined F-18-FDG PET/CT: Effect on quantitative and clinical assessment.
    European journal of radiology, 2012, Volume: 81, Issue:8

    Topics: Contrast Media; Dose-Response Relationship, Drug; Female; Fluorodeoxyglucose F18; Humans; Infusions,

2012
Advanced solid tumors treated with cediranib: comparison of dynamic contrast-enhanced MR imaging and CT as markers of vascular activity.
    Radiology, 2012, Volume: 265, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Contrast Media; Dose-Response Relations

2012
Optimized contrast-enhanced CT protocols for diagnostic whole-body 18F-FDG PET/CT: technical aspects of single-phase versus multiphase CT imaging.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:3

    Topics: Artifacts; Biotechnology; Contrast Media; Feasibility Studies; Female; Fluorodeoxyglucose F18; Human

2006

Other Studies

24 other studies available for iohexol and Benign Neoplasms

ArticleYear
Glomerular filtration rate in children and young adults with haemato-oncological disease and infection is best described by three-compartment iohexol model.
    Pediatric blood & cancer, 2022, Volume: 69, Issue:1

    Topics: Adolescent; Adult; Child; Glomerular Filtration Rate; Humans; Infections; Iohexol; Kidney Diseases;

2022
Contrast media extravasation injury: a prospective observational cohort study.
    European journal of medical research, 2023, Oct-25, Volume: 28, Issue:1

    Topics: Adult; Contrast Media; Extravasation of Diagnostic and Therapeutic Materials; Humans; Iohexol; Neopl

2023
Computed tomographic-lymphography as a complementary technique for lymph node staging in dogs with malignant tumors of various sites.
    Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association, 2018, Volume: 59, Issue:2

    Topics: Animals; Contrast Media; Dog Diseases; Dogs; Female; Injections; Iohexol; Lymph Nodes; Lymphography;

2018
Value of 100 kVp scan with sinogram-affirmed iterative reconstruction algorithm on a single-source CT system during whole-body CT for radiation and contrast medium dose reduction: an intra-individual feasibility study.
    Clinical radiology, 2018, Volume: 73, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Contrast Media; Feasibility Studies; Female; Humans; Ima

2018
Synthesis of Bi
    Nanoscale, 2019, Aug-15, Volume: 11, Issue:32

    Topics: Animals; Bismuth; Cell Line, Tumor; Cell Survival; Infrared Rays; Iohexol; Mice; Nanostructures; Neo

2019
Temporary organ displacement coupled with image-guided, intensity-modulated radiotherapy for paraspinal tumors.
    Radiation oncology (London, England), 2013, Jun-24, Volume: 8

    Topics: Adult; Aged; Aged, 80 and over; Catheters; Contrast Media; Female; Humans; Iohexol; Male; Middle Age

2013
Incidence of contrast-induced nephropathy in hospitalised patients with cancer.
    European radiology, 2014, Volume: 24, Issue:1

    Topics: Adult; Contrast Media; Female; Humans; Incidence; Inpatients; Iohexol; Kidney Diseases; Male; Middle

2014
A new equation for estimating glomerular filtration rate in cancer patients.
    Chemotherapy, 2014, Volume: 60, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Anthropometry; Area Under Curve; Chromium Ra

2014
Contrast enhanced chest-MDCT in oncologic patients. Prospective evaluation of the prevalence of incidental pulmonary embolism and added value of thin reconstructions.
    European radiology, 2015, Volume: 25, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Contrast Media; False Negative Reactions; False P

2015
FDG PET and Split-Bolus Multi-Detector Row CT Fusion Imaging in Oncologic Patients: Preliminary Results.
    Radiology, 2016, Volume: 278, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Female; Fluorodeoxyglucose F18; Humans; Iohexol; Iop

2016
CT findings in patients with pericardial effusion: differentiation of malignant and benign disease.
    AJR. American journal of roentgenology, 2010, Volume: 194, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Biopsy; Chi-Square Distribution; Contrast Media; Diagnosis, Differen

2010
Hyperfiltration evaluated by glomerular filtration rate at diagnosis in children with cancer.
    Pediatric blood & cancer, 2011, Volume: 56, Issue:5

    Topics: Adolescent; Age Factors; Bone Marrow; Child; Child, Preschool; Contrast Media; Female; Glomerular Fi

2011
Supraclavicular lymph nodes detected by 18F-FDG PET/CT in cancer patients: assessment with 18F-FDG PET/CT and sonography.
    AJR. American journal of roentgenology, 2012, Volume: 198, Issue:1

    Topics: Adult; Aged; Biopsy, Fine-Needle; Clavicle; Contrast Media; Diagnosis, Differential; Female; Fluorod

2012
Focal tracer uptake: a potential artifact in contrast-enhanced dual-modality PET/CT scans.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2002, Volume: 43, Issue:10

    Topics: Artifacts; Body Surface Area; Contrast Media; Fluorodeoxyglucose F18; Humans; Image Processing, Comp

2002
Correct evaluation of renal glomerular filtration rate requires clearance assays.
    Pediatric nephrology (Berlin, Germany), 2002, Volume: 17, Issue:10

    Topics: Adolescent; Albuminuria; Body Surface Area; Child; Child, Preschool; Contrast Media; Creatinine; Fem

2002
Volumetric computed tomography (VCT): a new technology for noninvasive, high-resolution monitoring of tumor angiogenesis.
    Nature medicine, 2004, Volume: 10, Issue:10

    Topics: Animals; Barium Sulfate; Histological Techniques; Iohexol; Iopamidol; Magnetic Resonance Imaging; Mi

2004
Adequate evaluation of image registration in hybrid PET/CT.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:9

    Topics: Artifacts; Biotechnology; Contrast Media; Feasibility Studies; Female; Fluorodeoxyglucose F18; Human

2006
Extracellular distribution volumes of hydrophilic solutes used to measure the glomerular filtration rate: comparison between chromium-51-EDTA and iohexol.
    Physiological measurement, 2007, Volume: 28, Issue:2

    Topics: Adult; Aged; Algorithms; Contrast Media; Data Interpretation, Statistical; Diabetes Mellitus; Eating

2007
Anterior layering of excreted 18F-FDG in the bladder on PET/CT: frequency and cause.
    AJR. American journal of roentgenology, 2007, Volume: 189, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Contrast Media; Female; Fluorodeoxyglucose F18; Humans;

2007
D-dimer assay to exclude pulmonary embolism in high-risk oncologic population: correlation with CT pulmonary angiography in an urgent care setting.
    Radiology, 2008, Volume: 247, Issue:3

    Topics: Adult; Angiography; Contrast Media; Emergencies; Female; Fibrin Fibrinogen Degradation Products; Hum

2008
In vitro effect of contrast agents during immunoradiometric assay for tumour-associated antigens.
    Nuclear medicine communications, 1998, Volume: 19, Issue:1

    Topics: Aged; Aged, 80 and over; Antigens, Neoplasm; Antigens, Tumor-Associated, Carbohydrate; Biomarkers, T

1998
Unsuspected pulmonary embolism: prospective detection on routine helical CT scans.
    Radiology, 1998, Volume: 208, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiography; Arteries; Cineradiography; Computer Systems

1998
Percutaneous CT lymphography using a new polyiodinated biomimetic microemulsion.
    Academic radiology, 2002, Volume: 9 Suppl 1

    Topics: Animals; Chylomicrons; Contrast Media; Dogs; Iodine; Iohexol; Liposomes; Lymph Nodes; Lymphography;

2002
Lumbar epidurography and epidural analgesia in cancer patients.
    Pain, 1989, Volume: 36, Issue:3

    Topics: Adult; Analgesia, Epidural; Bupivacaine; Epidural Space; Female; Humans; Iohexol; Lumbosacral Region

1989