Page last updated: 2024-10-29

iohexol and Angiogenesis, Pathologic

iohexol has been researched along with Angiogenesis, Pathologic in 31 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Research Excerpts

ExcerptRelevanceReference
"Dual-energy dynamic multiphase CT can measure iodine content in lung adenocarcinoma."7.83Dual-energy dynamic CT of lung adenocarcinoma: correlation of iodine uptake with tumor gene expression. ( Fujiwara, M; Gyobu, T; Hata, A; Honda, O; Morii, E; Tomiyama, N; Ueda, K; Yanagawa, M, 2016)
"Dual-energy dynamic multiphase CT can measure iodine content in lung adenocarcinoma."3.83Dual-energy dynamic CT of lung adenocarcinoma: correlation of iodine uptake with tumor gene expression. ( Fujiwara, M; Gyobu, T; Hata, A; Honda, O; Morii, E; Tomiyama, N; Ueda, K; Yanagawa, M, 2016)
"69 patients with metastatic renal cell carcinoma had dynamic contrast-enhanced CT scans at baseline and after 5 and 10 weeks of treatment."1.48Use of patient outcome endpoints to identify the best functional CT imaging parameters in metastatic renal cell carcinoma patients. ( Donskov, F; Madsen, HHT; Mains, JR; Pedersen, EM; Rasmussen, F; Thorup, K; Thygesen, J, 2018)
"Although hepatocellular carcinoma (HCC) demonstrates characteristic hypervascularity, some HCCs have a hypovascular pattern on computed tomography (CT)."1.38Prognostic implications of tumor vascularity and its relationship to cytokeratin 19 expression in patients with hepatocellular carcinoma. ( Chung, GE; Jang, JJ; Kim, SH; Kim, YJ; Lee, HS; Lee, JH; Lee, JM; Lee, K; Myung, SJ; Suh, KS; Yoon, JH, 2012)
"Thirty-two patients with oesophageal squamous cell carcinomas underwent first-pass perfusion with 64-section MDCT at 50 mAs."1.38Quantitative assessment of first-pass perfusion using a low-dose method at multidetector CT in oesophageal squamous cell carcinoma: correlation with VEGF expression. ( Chen, HJ; Chen, TW; Dong, ZH; He, D; Li, Y; Tang, SS; Yang, ZG; Yao, J, 2012)
"In 20 patients with hepatocellular carcinomas, multiphasic liver CT scans including arterial, portal, and equilibrium phases were performed."1.36Image fusion in dual energy computed tomography for detection of hypervascular liver hepatocellular carcinoma: phantom and preliminary studies. ( Cho, SH; Choi, BI; Han, JK; Kim, KS; Kim, KW; Kim, SH; Kim, SJ; Lee, JM, 2010)
"VCT shows the vessel architecture of tumors and animals with greater detail and plasticity than has previously been achieved, and is superior to contrast-enhanced magnetic resonance (MR) angiography."1.32Volumetric computed tomography (VCT): a new technology for noninvasive, high-resolution monitoring of tumor angiogenesis. ( Bock, M; Fink, C; Fusenig, NE; Greschus, S; Kiessling, F; Lichy, MP; Moll, J; Mueller, MM; Semmler, W; Traupe, H; Vosseler, S, 2004)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.23)18.2507
2000's7 (22.58)29.6817
2010's21 (67.74)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Manoharan, D1
Netaji, A1
Das, CJ1
Sharma, S1
Li, Q1
Li, X1
Li, XY1
Huo, JW1
Lv, FJ1
Luo, TY1
Mains, JR1
Donskov, F1
Pedersen, EM1
Madsen, HHT1
Thygesen, J1
Thorup, K1
Rasmussen, F1
Dighe, S2
Blake, H2
Jeyadevan, N2
Castellano, I2
Koh, DM1
Orton, M2
Chandler, I1
Swift, I2
Brown, G2
Ichikawa, T1
Okada, M1
Kondo, H1
Sou, H1
Murakami, T1
Kanematsu, M1
Yoshikawa, S1
Shiosakai, K1
Hayakawa, A1
Awai, K1
Yoshimitsu, K1
Yamashita, Y1
Sun, H2
Xu, Y1
Yang, Q1
Wang, W1
Kaufmann, S1
Schulze, M1
Spira, D2
Horger, M2
Chung, YE1
You, JS1
Lee, HJ2
Lim, JS1
Lee, HS2
Baek, SE1
Kim, MJ1
Kim, JI1
Goo, JM1
Kim, MA1
Chung, DH1
Yanagawa, M1
Morii, E1
Hata, A1
Fujiwara, M1
Gyobu, T1
Ueda, K1
Honda, O1
Tomiyama, N1
Anemone, A1
Consolino, L1
Longo, DL1
Harri, PA1
Chung, A1
Tridandapani, S1
Nandwana, S1
Ibraheem, OO1
Cox, K1
Murphy, F1
Mittal, P1
Small, W1
Kaneoya, K1
Ueda, T1
Suito, H1
Nanazawa, Y1
Tamaru, J1
Isobe, K1
Naya, Y1
Tobe, T1
Motoori, K1
Yamamoto, S1
Rubin, GD1
Minami, M1
Ito, H1
Hata, H1
Mori, H1
Matsumoto, S1
Yamada, Y1
Kiyosue, H1
Tanoue, S1
Hongo, N1
Kashima, K1
Akashi-Tanaka, S1
Shien, T1
Tsukagoshi, S1
Funabasama, S1
Miyagawa, K1
Terada, K1
Yoshida, M1
Hojo, T1
Kinoshita, T1
Moriyama, N2
Jiang, HJ1
Zhang, ZR1
Shen, BZ2
Wan, Y1
Guo, H1
Shu, SJ1
Kim, KS1
Lee, JM2
Kim, SH2
Kim, KW1
Kim, SJ1
Cho, SH1
Han, JK1
Choi, BI1
Chen, TW2
Yang, ZG2
Wang, QL1
Li, Y2
Qian, LL1
Chen, HJ2
Qin, HY1
Sun, HR1
Li, YJ1
Chung, GE1
Lee, JH1
Yoon, JH1
Myung, SJ1
Lee, K1
Jang, JJ1
Suh, KS1
Kim, YJ1
Tang, SS1
Yao, J1
Dong, ZH1
He, D1
Castellano, E1
Koh, MU1
Orten, M1
Adam, P1
Linder, C1
Spira, SM1
Pintoffl, J1
Claussen, CD1
Stewart, EE1
Chen, X1
Schafer, PH1
Chen, Y1
Garcia, BM1
Lee, TY2
Messiou, C1
Ang, JE1
Collins, DJ1
Morgan, VA1
Mears, D1
Papadatos-Pastos, D1
Brunetto, A1
Tunariu, N1
Mann, H1
Tessier, J1
Young, H1
Ghiorghiu, D1
Marley, S1
Kaye, SB1
deBono, JS1
Leach, MO1
deSouza, NM1
Osimani, M1
Bellini, D1
Di Cristofano, C1
Palleschi, G1
Petrozza, V1
Carbone, A1
Laghi, A1
Roberts, HC1
Roberts, TP1
Dillon, WP1
Kiessling, F1
Greschus, S1
Lichy, MP1
Bock, M1
Fink, C1
Vosseler, S1
Moll, J1
Mueller, MM1
Fusenig, NE1
Traupe, H1
Semmler, W1
Iinuma, G1
Satake, M1
Miyakawa, K1
Tateishi, U1
Uchiyama, N1
Akasu, T1
Fujii, T1
Kobayashi, T1
Dromain, C1
Balleyguier, C1
Muller, S1
Mathieu, MC1
Rochard, F1
Opolon, P1
Sigal, R1
Pacella, CM1
Bizzarri, G1
Anelli, V1
Valle, D1
Fabbrini, R1
Bianchini, A1
Fenderico, P1
Rossi, Z1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Computed Tomography Perfusion of Colorectal Cancer in Correlation With Tumor Grade[NCT03448302]50 participants (Anticipated)Observational2018-03-10Not yet recruiting
Exploratory Open-Label, Non-randomised, Single Centre Methodology Study Comparing DCE-CT and DCE-MRI as Markers of Changes in Vascular Activity Mediated by a Positive Control Agent [Cediranib (Recentin™; AZD2171), a Potent Inhibitor of VEGF-driven Angioge[NCT00748891]Phase 135 participants (Anticipated)Interventional2008-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for iohexol and Angiogenesis, Pathologic

ArticleYear
Advanced solid tumors treated with cediranib: comparison of dynamic contrast-enhanced MR imaging and CT as markers of vascular activity.
    Radiology, 2012, Volume: 265, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Contrast Media; Dose-Response Relations

2012

Other Studies

30 other studies available for iohexol and Angiogenesis, Pathologic

ArticleYear
Iodine Parameters in Triple-Bolus Dual-Energy CT Correlate With Perfusion CT Biomarkers of Angiogenesis in Renal Cell Carcinoma.
    AJR. American journal of roentgenology, 2020, Volume: 214, Issue:4

    Topics: Adult; Aged; Carcinoma, Renal Cell; Contrast Media; Female; Humans; Iohexol; Kidney Neoplasms; Male;

2020
Spectral CT in Lung Cancer: Usefulness of Iodine Concentration for Evaluation of Tumor Angiogenesis and Prognosis.
    AJR. American journal of roentgenology, 2020, Volume: 215, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Iohexol; Lung Neoplasms; Male; Middl

2020
Use of patient outcome endpoints to identify the best functional CT imaging parameters in metastatic renal cell carcinoma patients.
    The British journal of radiology, 2018, Volume: 91, Issue:1082

    Topics: Blood Flow Velocity; Blood Volume; Carcinoma, Renal Cell; Contrast Media; Four-Dimensional Computed

2018
Perfusion CT vascular parameters do not correlate with immunohistochemically derived microvessel density count in colorectal tumors.
    Radiology, 2013, Volume: 268, Issue:2

    Topics: Aged; Aged, 80 and over; Artifacts; Colorectal Neoplasms; Contrast Media; Female; Humans; Immunoenzy

2013
Recommended iodine dose for multiphasic contrast-enhanced mutidetector-row computed tomography imaging of liver for assessing hypervascular hepatocellular carcinoma: multicenter prospective study in 77 general hospitals in Japan.
    Academic radiology, 2013, Volume: 20, Issue:9

    Topics: Aged; Carcinoma, Hepatocellular; Contrast Media; Dose-Response Relationship, Drug; Female; Hospitals

2013
Assessment of tumor grade and angiogenesis in colorectal cancer: whole-volume perfusion CT.
    Academic radiology, 2014, Volume: 21, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Colon; Colorectal Neoplasms; Contrast Media; Female;

2014
Comparison of volume perfusion computed tomography and contrast-enhanced ultrasound for assessment of therapeutic effect of transarterial chemoembolization in patients with hepatocellular carcinoma: a preliminary report.
    Acta radiologica (Stockholm, Sweden : 1987), 2016, Volume: 57, Issue:1

    Topics: Aged; Aged, 80 and over; Blood Volume; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Co

2016
Possible Contrast Media Reduction with Low keV Monoenergetic Images in the Detection of Focal Liver Lesions: A Dual-Energy CT Animal Study.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Animals; Aortography; Contrast Media; Dose-Response Relationship, Drug; Feasibility Studies; Iohexol

2015
Correlation of volumetric perfusion CT parameters with hypoxia inducible factor-1 alpha expression in a rabbit VX2 tumor model.
    Acta radiologica (Stockholm, Sweden : 1987), 2016, Volume: 57, Issue:6

    Topics: Animals; Cone-Beam Computed Tomography; Contrast Media; Disease Models, Animal; Hypoxia-Inducible Fa

2016
Dual-energy dynamic CT of lung adenocarcinoma: correlation of iodine uptake with tumor gene expression.
    European journal of radiology, 2016, Volume: 85, Issue:8

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Aged, 80 and over; Contrast Media; ErbB Receptors; Fem

2016
MRI-CEST assessment of tumour perfusion using X-ray iodinated agents: comparison with a conventional Gd-based agent.
    European radiology, 2017, Volume: 27, Issue:5

    Topics: Animals; Contrast Media; Female; Gadolinium; Heterocyclic Compounds; Image Enhancement; Iohexol; Iop

2017
Extra-hepatic sarcoma metastasis surveillance in the liver: is arterial phase imaging necessary?
    Abdominal radiology (New York), 2017, Volume: 42, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Iohexol; Liver Neoplasms; Male; Midd

2017
Functional computed tomography imaging of tumor-induced angiogenesis: preliminary results of new tracer kinetic modeling using a computer discretization approach.
    Radiation medicine, 2008, Volume: 26, Issue:4

    Topics: Adult; Aged; Angiography, Digital Subtraction; Carcinoma, Renal Cell; Computer Simulation; Contrast

2008
Fibrous stroma and vascularity of pancreatic carcinoma: correlation with enhancement patterns on CT.
    Abdominal imaging, 2010, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Aged; Azo Compounds; Carcinoma, Pancreatic Ductal; Coloring Agents; Contrast Media;

2010
Whole-breast volume perfusion images using 256-row multislice computed tomography: visualization of lesions with ductal spread.
    Breast cancer (Tokyo, Japan), 2009, Volume: 16, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Ductal, Breast; Cont

2009
Functional CT for assessment of early vascular physiology in liver tumors.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2008, Volume: 7, Issue:5

    Topics: Animals; Blood Flow Velocity; Blood Volume; Capillary Permeability; Cineangiography; Contrast Media;

2008
Image fusion in dual energy computed tomography for detection of hypervascular liver hepatocellular carcinoma: phantom and preliminary studies.
    Investigative radiology, 2010, Volume: 45, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Carcinoma, Hepatocellular; Contrast Media; Female; Humans; Iohexo

2010
Whole tumour quantitative measurement of first-pass perfusion of oesophageal squamous cell carcinoma using 64-row multidetector computed tomography: correlation with microvessel density.
    European journal of radiology, 2011, Volume: 79, Issue:2

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Contrast Media; Esophageal Neoplasms; Female; Humans; Immunoe

2011
Application of CT perfusion imaging to the histological differentiation of adrenal gland tumors.
    European journal of radiology, 2012, Volume: 81, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Algorithms; Blood Volume; Contrast Media; Diagnosis, Differential;

2012
Prognostic implications of tumor vascularity and its relationship to cytokeratin 19 expression in patients with hepatocellular carcinoma.
    Abdominal imaging, 2012, Volume: 37, Issue:3

    Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Chi-Square Distribution; Contrast Media; Female; Human

2012
Quantitative assessment of first-pass perfusion using a low-dose method at multidetector CT in oesophageal squamous cell carcinoma: correlation with VEGF expression.
    Clinical radiology, 2012, Volume: 67, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Blood Volume; Carcinoma, Squamous Cell; Contrast Media; Esophageal N

2012
Perfusion CT to assess angiogenesis in colon cancer: technical limitations and practical challenges.
    The British journal of radiology, 2012, Volume: 85, Issue:1018

    Topics: Colonic Neoplasms; Contrast Media; Feasibility Studies; Humans; Iliac Artery; Iohexol; Movement; Neo

2012
Perfusion and flow extraction product as potential discriminators in untreated follicular and diffuse large B cell lymphomas using volume perfusion CT with attempt at histopathologic explanation.
    AJR. American journal of roentgenology, 2012, Volume: 198, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Blood Flow Velocity; Blood Volume; Contrast Media; Femal

2012
Effect of an angiogenesis inhibitor on hepatic tumor perfusion and the implications for adjuvant cytotoxic therapy.
    Radiology, 2012, Volume: 264, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Contrast Media; Disease Models, Animal; Immunohistochemistry; Iohe

2012
Perfusion MDCT of prostate cancer: correlation of perfusion CT parameters and immunohistochemical markers of angiogenesis.
    AJR. American journal of roentgenology, 2012, Volume: 199, Issue:5

    Topics: Aged; Biopsy; Contrast Media; Humans; Immunohistochemistry; Iohexol; Male; Middle Aged; Neovasculari

2012
Dynamic contrast-enhanced computed tomography (CT) for quantitative estimation of microvascular permeability in human brain tumors.
    Academic radiology, 2002, Volume: 9 Suppl 2

    Topics: Adenocarcinoma; Aged; Blood Volume; Brain Neoplasms; Capillary Permeability; Contrast Media; Female;

2002
Volumetric computed tomography (VCT): a new technology for noninvasive, high-resolution monitoring of tumor angiogenesis.
    Nature medicine, 2004, Volume: 10, Issue:10

    Topics: Animals; Barium Sulfate; Histological Techniques; Iohexol; Iopamidol; Magnetic Resonance Imaging; Mi

2004
Vascular virtual endoluminal visualization of invasive colorectal cancer on MDCT colonography.
    AJR. American journal of roentgenology, 2005, Volume: 184, Issue:4

    Topics: Adult; Aged; Colonography, Computed Tomographic; Colorectal Neoplasms; Contrast Media; Female; Human

2005
Evaluation of tumor angiogenesis of breast carcinoma using contrast-enhanced digital mammography.
    AJR. American journal of roentgenology, 2006, Volume: 187, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Contrast Media; Humans; Iohexol; Mammography; Midd

2006
Evaluation of the vascular pattern of hepatocellular carcinoma with dynamic computed tomography and its use in identifying optimal temporal windows for helical computed tomography.
    European radiology, 1998, Volume: 8, Issue:1

    Topics: Aged; Aorta, Abdominal; Carcinoma, Hepatocellular; Contrast Media; Evaluation Studies as Topic; Fema

1998