iohexol has been researched along with Angiogenesis, Pathologic in 31 studies
Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dual-energy dynamic multiphase CT can measure iodine content in lung adenocarcinoma." | 7.83 | Dual-energy dynamic CT of lung adenocarcinoma: correlation of iodine uptake with tumor gene expression. ( Fujiwara, M; Gyobu, T; Hata, A; Honda, O; Morii, E; Tomiyama, N; Ueda, K; Yanagawa, M, 2016) |
| "Dual-energy dynamic multiphase CT can measure iodine content in lung adenocarcinoma." | 3.83 | Dual-energy dynamic CT of lung adenocarcinoma: correlation of iodine uptake with tumor gene expression. ( Fujiwara, M; Gyobu, T; Hata, A; Honda, O; Morii, E; Tomiyama, N; Ueda, K; Yanagawa, M, 2016) |
| "69 patients with metastatic renal cell carcinoma had dynamic contrast-enhanced CT scans at baseline and after 5 and 10 weeks of treatment." | 1.48 | Use of patient outcome endpoints to identify the best functional CT imaging parameters in metastatic renal cell carcinoma patients. ( Donskov, F; Madsen, HHT; Mains, JR; Pedersen, EM; Rasmussen, F; Thorup, K; Thygesen, J, 2018) |
| "Although hepatocellular carcinoma (HCC) demonstrates characteristic hypervascularity, some HCCs have a hypovascular pattern on computed tomography (CT)." | 1.38 | Prognostic implications of tumor vascularity and its relationship to cytokeratin 19 expression in patients with hepatocellular carcinoma. ( Chung, GE; Jang, JJ; Kim, SH; Kim, YJ; Lee, HS; Lee, JH; Lee, JM; Lee, K; Myung, SJ; Suh, KS; Yoon, JH, 2012) |
| "Thirty-two patients with oesophageal squamous cell carcinomas underwent first-pass perfusion with 64-section MDCT at 50 mAs." | 1.38 | Quantitative assessment of first-pass perfusion using a low-dose method at multidetector CT in oesophageal squamous cell carcinoma: correlation with VEGF expression. ( Chen, HJ; Chen, TW; Dong, ZH; He, D; Li, Y; Tang, SS; Yang, ZG; Yao, J, 2012) |
| "In 20 patients with hepatocellular carcinomas, multiphasic liver CT scans including arterial, portal, and equilibrium phases were performed." | 1.36 | Image fusion in dual energy computed tomography for detection of hypervascular liver hepatocellular carcinoma: phantom and preliminary studies. ( Cho, SH; Choi, BI; Han, JK; Kim, KS; Kim, KW; Kim, SH; Kim, SJ; Lee, JM, 2010) |
| "VCT shows the vessel architecture of tumors and animals with greater detail and plasticity than has previously been achieved, and is superior to contrast-enhanced magnetic resonance (MR) angiography." | 1.32 | Volumetric computed tomography (VCT): a new technology for noninvasive, high-resolution monitoring of tumor angiogenesis. ( Bock, M; Fink, C; Fusenig, NE; Greschus, S; Kiessling, F; Lichy, MP; Moll, J; Mueller, MM; Semmler, W; Traupe, H; Vosseler, S, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 7 (22.58) | 29.6817 |
| 2010's | 21 (67.74) | 24.3611 |
| 2020's | 2 (6.45) | 2.80 |
| Authors | Studies |
|---|---|
| Manoharan, D | 1 |
| Netaji, A | 1 |
| Das, CJ | 1 |
| Sharma, S | 1 |
| Li, Q | 1 |
| Li, X | 1 |
| Li, XY | 1 |
| Huo, JW | 1 |
| Lv, FJ | 1 |
| Luo, TY | 1 |
| Mains, JR | 1 |
| Donskov, F | 1 |
| Pedersen, EM | 1 |
| Madsen, HHT | 1 |
| Thygesen, J | 1 |
| Thorup, K | 1 |
| Rasmussen, F | 1 |
| Dighe, S | 2 |
| Blake, H | 2 |
| Jeyadevan, N | 2 |
| Castellano, I | 2 |
| Koh, DM | 1 |
| Orton, M | 2 |
| Chandler, I | 1 |
| Swift, I | 2 |
| Brown, G | 2 |
| Ichikawa, T | 1 |
| Okada, M | 1 |
| Kondo, H | 1 |
| Sou, H | 1 |
| Murakami, T | 1 |
| Kanematsu, M | 1 |
| Yoshikawa, S | 1 |
| Shiosakai, K | 1 |
| Hayakawa, A | 1 |
| Awai, K | 1 |
| Yoshimitsu, K | 1 |
| Yamashita, Y | 1 |
| Sun, H | 2 |
| Xu, Y | 1 |
| Yang, Q | 1 |
| Wang, W | 1 |
| Kaufmann, S | 1 |
| Schulze, M | 1 |
| Spira, D | 2 |
| Horger, M | 2 |
| Chung, YE | 1 |
| You, JS | 1 |
| Lee, HJ | 2 |
| Lim, JS | 1 |
| Lee, HS | 2 |
| Baek, SE | 1 |
| Kim, MJ | 1 |
| Kim, JI | 1 |
| Goo, JM | 1 |
| Kim, MA | 1 |
| Chung, DH | 1 |
| Yanagawa, M | 1 |
| Morii, E | 1 |
| Hata, A | 1 |
| Fujiwara, M | 1 |
| Gyobu, T | 1 |
| Ueda, K | 1 |
| Honda, O | 1 |
| Tomiyama, N | 1 |
| Anemone, A | 1 |
| Consolino, L | 1 |
| Longo, DL | 1 |
| Harri, PA | 1 |
| Chung, A | 1 |
| Tridandapani, S | 1 |
| Nandwana, S | 1 |
| Ibraheem, OO | 1 |
| Cox, K | 1 |
| Murphy, F | 1 |
| Mittal, P | 1 |
| Small, W | 1 |
| Kaneoya, K | 1 |
| Ueda, T | 1 |
| Suito, H | 1 |
| Nanazawa, Y | 1 |
| Tamaru, J | 1 |
| Isobe, K | 1 |
| Naya, Y | 1 |
| Tobe, T | 1 |
| Motoori, K | 1 |
| Yamamoto, S | 1 |
| Rubin, GD | 1 |
| Minami, M | 1 |
| Ito, H | 1 |
| Hata, H | 1 |
| Mori, H | 1 |
| Matsumoto, S | 1 |
| Yamada, Y | 1 |
| Kiyosue, H | 1 |
| Tanoue, S | 1 |
| Hongo, N | 1 |
| Kashima, K | 1 |
| Akashi-Tanaka, S | 1 |
| Shien, T | 1 |
| Tsukagoshi, S | 1 |
| Funabasama, S | 1 |
| Miyagawa, K | 1 |
| Terada, K | 1 |
| Yoshida, M | 1 |
| Hojo, T | 1 |
| Kinoshita, T | 1 |
| Moriyama, N | 2 |
| Jiang, HJ | 1 |
| Zhang, ZR | 1 |
| Shen, BZ | 2 |
| Wan, Y | 1 |
| Guo, H | 1 |
| Shu, SJ | 1 |
| Kim, KS | 1 |
| Lee, JM | 2 |
| Kim, SH | 2 |
| Kim, KW | 1 |
| Kim, SJ | 1 |
| Cho, SH | 1 |
| Han, JK | 1 |
| Choi, BI | 1 |
| Chen, TW | 2 |
| Yang, ZG | 2 |
| Wang, QL | 1 |
| Li, Y | 2 |
| Qian, LL | 1 |
| Chen, HJ | 2 |
| Qin, HY | 1 |
| Sun, HR | 1 |
| Li, YJ | 1 |
| Chung, GE | 1 |
| Lee, JH | 1 |
| Yoon, JH | 1 |
| Myung, SJ | 1 |
| Lee, K | 1 |
| Jang, JJ | 1 |
| Suh, KS | 1 |
| Kim, YJ | 1 |
| Tang, SS | 1 |
| Yao, J | 1 |
| Dong, ZH | 1 |
| He, D | 1 |
| Castellano, E | 1 |
| Koh, MU | 1 |
| Orten, M | 1 |
| Adam, P | 1 |
| Linder, C | 1 |
| Spira, SM | 1 |
| Pintoffl, J | 1 |
| Claussen, CD | 1 |
| Stewart, EE | 1 |
| Chen, X | 1 |
| Schafer, PH | 1 |
| Chen, Y | 1 |
| Garcia, BM | 1 |
| Lee, TY | 2 |
| Messiou, C | 1 |
| Ang, JE | 1 |
| Collins, DJ | 1 |
| Morgan, VA | 1 |
| Mears, D | 1 |
| Papadatos-Pastos, D | 1 |
| Brunetto, A | 1 |
| Tunariu, N | 1 |
| Mann, H | 1 |
| Tessier, J | 1 |
| Young, H | 1 |
| Ghiorghiu, D | 1 |
| Marley, S | 1 |
| Kaye, SB | 1 |
| deBono, JS | 1 |
| Leach, MO | 1 |
| deSouza, NM | 1 |
| Osimani, M | 1 |
| Bellini, D | 1 |
| Di Cristofano, C | 1 |
| Palleschi, G | 1 |
| Petrozza, V | 1 |
| Carbone, A | 1 |
| Laghi, A | 1 |
| Roberts, HC | 1 |
| Roberts, TP | 1 |
| Dillon, WP | 1 |
| Kiessling, F | 1 |
| Greschus, S | 1 |
| Lichy, MP | 1 |
| Bock, M | 1 |
| Fink, C | 1 |
| Vosseler, S | 1 |
| Moll, J | 1 |
| Mueller, MM | 1 |
| Fusenig, NE | 1 |
| Traupe, H | 1 |
| Semmler, W | 1 |
| Iinuma, G | 1 |
| Satake, M | 1 |
| Miyakawa, K | 1 |
| Tateishi, U | 1 |
| Uchiyama, N | 1 |
| Akasu, T | 1 |
| Fujii, T | 1 |
| Kobayashi, T | 1 |
| Dromain, C | 1 |
| Balleyguier, C | 1 |
| Muller, S | 1 |
| Mathieu, MC | 1 |
| Rochard, F | 1 |
| Opolon, P | 1 |
| Sigal, R | 1 |
| Pacella, CM | 1 |
| Bizzarri, G | 1 |
| Anelli, V | 1 |
| Valle, D | 1 |
| Fabbrini, R | 1 |
| Bianchini, A | 1 |
| Fenderico, P | 1 |
| Rossi, Z | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Computed Tomography Perfusion of Colorectal Cancer in Correlation With Tumor Grade[NCT03448302] | 50 participants (Anticipated) | Observational | 2018-03-10 | Not yet recruiting | |||
| Exploratory Open-Label, Non-randomised, Single Centre Methodology Study Comparing DCE-CT and DCE-MRI as Markers of Changes in Vascular Activity Mediated by a Positive Control Agent [Cediranib (Recentin™; AZD2171), a Potent Inhibitor of VEGF-driven Angioge[NCT00748891] | Phase 1 | 35 participants (Anticipated) | Interventional | 2008-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for iohexol and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Advanced solid tumors treated with cediranib: comparison of dynamic contrast-enhanced MR imaging and CT as markers of vascular activity.
Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Contrast Media; Dose-Response Relations | 2012 |
30 other studies available for iohexol and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Iodine Parameters in Triple-Bolus Dual-Energy CT Correlate With Perfusion CT Biomarkers of Angiogenesis in Renal Cell Carcinoma.
Topics: Adult; Aged; Carcinoma, Renal Cell; Contrast Media; Female; Humans; Iohexol; Kidney Neoplasms; Male; | 2020 |
Spectral CT in Lung Cancer: Usefulness of Iodine Concentration for Evaluation of Tumor Angiogenesis and Prognosis.
Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Iohexol; Lung Neoplasms; Male; Middl | 2020 |
Use of patient outcome endpoints to identify the best functional CT imaging parameters in metastatic renal cell carcinoma patients.
Topics: Blood Flow Velocity; Blood Volume; Carcinoma, Renal Cell; Contrast Media; Four-Dimensional Computed | 2018 |
Perfusion CT vascular parameters do not correlate with immunohistochemically derived microvessel density count in colorectal tumors.
Topics: Aged; Aged, 80 and over; Artifacts; Colorectal Neoplasms; Contrast Media; Female; Humans; Immunoenzy | 2013 |
Recommended iodine dose for multiphasic contrast-enhanced mutidetector-row computed tomography imaging of liver for assessing hypervascular hepatocellular carcinoma: multicenter prospective study in 77 general hospitals in Japan.
Topics: Aged; Carcinoma, Hepatocellular; Contrast Media; Dose-Response Relationship, Drug; Female; Hospitals | 2013 |
Assessment of tumor grade and angiogenesis in colorectal cancer: whole-volume perfusion CT.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Colon; Colorectal Neoplasms; Contrast Media; Female; | 2014 |
Comparison of volume perfusion computed tomography and contrast-enhanced ultrasound for assessment of therapeutic effect of transarterial chemoembolization in patients with hepatocellular carcinoma: a preliminary report.
Topics: Aged; Aged, 80 and over; Blood Volume; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Co | 2016 |
Possible Contrast Media Reduction with Low keV Monoenergetic Images in the Detection of Focal Liver Lesions: A Dual-Energy CT Animal Study.
Topics: Animals; Aortography; Contrast Media; Dose-Response Relationship, Drug; Feasibility Studies; Iohexol | 2015 |
Correlation of volumetric perfusion CT parameters with hypoxia inducible factor-1 alpha expression in a rabbit VX2 tumor model.
Topics: Animals; Cone-Beam Computed Tomography; Contrast Media; Disease Models, Animal; Hypoxia-Inducible Fa | 2016 |
Dual-energy dynamic CT of lung adenocarcinoma: correlation of iodine uptake with tumor gene expression.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Aged, 80 and over; Contrast Media; ErbB Receptors; Fem | 2016 |
MRI-CEST assessment of tumour perfusion using X-ray iodinated agents: comparison with a conventional Gd-based agent.
Topics: Animals; Contrast Media; Female; Gadolinium; Heterocyclic Compounds; Image Enhancement; Iohexol; Iop | 2017 |
Extra-hepatic sarcoma metastasis surveillance in the liver: is arterial phase imaging necessary?
Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Iohexol; Liver Neoplasms; Male; Midd | 2017 |
Functional computed tomography imaging of tumor-induced angiogenesis: preliminary results of new tracer kinetic modeling using a computer discretization approach.
Topics: Adult; Aged; Angiography, Digital Subtraction; Carcinoma, Renal Cell; Computer Simulation; Contrast | 2008 |
Fibrous stroma and vascularity of pancreatic carcinoma: correlation with enhancement patterns on CT.
Topics: Adenocarcinoma; Aged; Azo Compounds; Carcinoma, Pancreatic Ductal; Coloring Agents; Contrast Media; | 2010 |
Whole-breast volume perfusion images using 256-row multislice computed tomography: visualization of lesions with ductal spread.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Ductal, Breast; Cont | 2009 |
Functional CT for assessment of early vascular physiology in liver tumors.
Topics: Animals; Blood Flow Velocity; Blood Volume; Capillary Permeability; Cineangiography; Contrast Media; | 2008 |
Image fusion in dual energy computed tomography for detection of hypervascular liver hepatocellular carcinoma: phantom and preliminary studies.
Topics: Adult; Aged; Analysis of Variance; Carcinoma, Hepatocellular; Contrast Media; Female; Humans; Iohexo | 2010 |
Whole tumour quantitative measurement of first-pass perfusion of oesophageal squamous cell carcinoma using 64-row multidetector computed tomography: correlation with microvessel density.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Contrast Media; Esophageal Neoplasms; Female; Humans; Immunoe | 2011 |
Application of CT perfusion imaging to the histological differentiation of adrenal gland tumors.
Topics: Adenoma; Adrenal Gland Neoplasms; Algorithms; Blood Volume; Contrast Media; Diagnosis, Differential; | 2012 |
Prognostic implications of tumor vascularity and its relationship to cytokeratin 19 expression in patients with hepatocellular carcinoma.
Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Chi-Square Distribution; Contrast Media; Female; Human | 2012 |
Quantitative assessment of first-pass perfusion using a low-dose method at multidetector CT in oesophageal squamous cell carcinoma: correlation with VEGF expression.
Topics: Adult; Aged; Aged, 80 and over; Blood Volume; Carcinoma, Squamous Cell; Contrast Media; Esophageal N | 2012 |
Perfusion CT to assess angiogenesis in colon cancer: technical limitations and practical challenges.
Topics: Colonic Neoplasms; Contrast Media; Feasibility Studies; Humans; Iliac Artery; Iohexol; Movement; Neo | 2012 |
Perfusion and flow extraction product as potential discriminators in untreated follicular and diffuse large B cell lymphomas using volume perfusion CT with attempt at histopathologic explanation.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Blood Flow Velocity; Blood Volume; Contrast Media; Femal | 2012 |
Effect of an angiogenesis inhibitor on hepatic tumor perfusion and the implications for adjuvant cytotoxic therapy.
Topics: Angiogenesis Inhibitors; Animals; Contrast Media; Disease Models, Animal; Immunohistochemistry; Iohe | 2012 |
Perfusion MDCT of prostate cancer: correlation of perfusion CT parameters and immunohistochemical markers of angiogenesis.
Topics: Aged; Biopsy; Contrast Media; Humans; Immunohistochemistry; Iohexol; Male; Middle Aged; Neovasculari | 2012 |
Dynamic contrast-enhanced computed tomography (CT) for quantitative estimation of microvascular permeability in human brain tumors.
Topics: Adenocarcinoma; Aged; Blood Volume; Brain Neoplasms; Capillary Permeability; Contrast Media; Female; | 2002 |
Volumetric computed tomography (VCT): a new technology for noninvasive, high-resolution monitoring of tumor angiogenesis.
Topics: Animals; Barium Sulfate; Histological Techniques; Iohexol; Iopamidol; Magnetic Resonance Imaging; Mi | 2004 |
Vascular virtual endoluminal visualization of invasive colorectal cancer on MDCT colonography.
Topics: Adult; Aged; Colonography, Computed Tomographic; Colorectal Neoplasms; Contrast Media; Female; Human | 2005 |
Evaluation of tumor angiogenesis of breast carcinoma using contrast-enhanced digital mammography.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Contrast Media; Humans; Iohexol; Mammography; Midd | 2006 |
Evaluation of the vascular pattern of hepatocellular carcinoma with dynamic computed tomography and its use in identifying optimal temporal windows for helical computed tomography.
Topics: Aged; Aorta, Abdominal; Carcinoma, Hepatocellular; Contrast Media; Evaluation Studies as Topic; Fema | 1998 |