iohexol has been researched along with Angiogenesis, Pathologic in 31 studies
Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.
Excerpt | Relevance | Reference |
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"Dual-energy dynamic multiphase CT can measure iodine content in lung adenocarcinoma." | 7.83 | Dual-energy dynamic CT of lung adenocarcinoma: correlation of iodine uptake with tumor gene expression. ( Fujiwara, M; Gyobu, T; Hata, A; Honda, O; Morii, E; Tomiyama, N; Ueda, K; Yanagawa, M, 2016) |
"Dual-energy dynamic multiphase CT can measure iodine content in lung adenocarcinoma." | 3.83 | Dual-energy dynamic CT of lung adenocarcinoma: correlation of iodine uptake with tumor gene expression. ( Fujiwara, M; Gyobu, T; Hata, A; Honda, O; Morii, E; Tomiyama, N; Ueda, K; Yanagawa, M, 2016) |
"69 patients with metastatic renal cell carcinoma had dynamic contrast-enhanced CT scans at baseline and after 5 and 10 weeks of treatment." | 1.48 | Use of patient outcome endpoints to identify the best functional CT imaging parameters in metastatic renal cell carcinoma patients. ( Donskov, F; Madsen, HHT; Mains, JR; Pedersen, EM; Rasmussen, F; Thorup, K; Thygesen, J, 2018) |
"Although hepatocellular carcinoma (HCC) demonstrates characteristic hypervascularity, some HCCs have a hypovascular pattern on computed tomography (CT)." | 1.38 | Prognostic implications of tumor vascularity and its relationship to cytokeratin 19 expression in patients with hepatocellular carcinoma. ( Chung, GE; Jang, JJ; Kim, SH; Kim, YJ; Lee, HS; Lee, JH; Lee, JM; Lee, K; Myung, SJ; Suh, KS; Yoon, JH, 2012) |
"Thirty-two patients with oesophageal squamous cell carcinomas underwent first-pass perfusion with 64-section MDCT at 50 mAs." | 1.38 | Quantitative assessment of first-pass perfusion using a low-dose method at multidetector CT in oesophageal squamous cell carcinoma: correlation with VEGF expression. ( Chen, HJ; Chen, TW; Dong, ZH; He, D; Li, Y; Tang, SS; Yang, ZG; Yao, J, 2012) |
"In 20 patients with hepatocellular carcinomas, multiphasic liver CT scans including arterial, portal, and equilibrium phases were performed." | 1.36 | Image fusion in dual energy computed tomography for detection of hypervascular liver hepatocellular carcinoma: phantom and preliminary studies. ( Cho, SH; Choi, BI; Han, JK; Kim, KS; Kim, KW; Kim, SH; Kim, SJ; Lee, JM, 2010) |
"VCT shows the vessel architecture of tumors and animals with greater detail and plasticity than has previously been achieved, and is superior to contrast-enhanced magnetic resonance (MR) angiography." | 1.32 | Volumetric computed tomography (VCT): a new technology for noninvasive, high-resolution monitoring of tumor angiogenesis. ( Bock, M; Fink, C; Fusenig, NE; Greschus, S; Kiessling, F; Lichy, MP; Moll, J; Mueller, MM; Semmler, W; Traupe, H; Vosseler, S, 2004) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (3.23) | 18.2507 |
2000's | 7 (22.58) | 29.6817 |
2010's | 21 (67.74) | 24.3611 |
2020's | 2 (6.45) | 2.80 |
Authors | Studies |
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Manoharan, D | 1 |
Netaji, A | 1 |
Das, CJ | 1 |
Sharma, S | 1 |
Li, Q | 1 |
Li, X | 1 |
Li, XY | 1 |
Huo, JW | 1 |
Lv, FJ | 1 |
Luo, TY | 1 |
Mains, JR | 1 |
Donskov, F | 1 |
Pedersen, EM | 1 |
Madsen, HHT | 1 |
Thygesen, J | 1 |
Thorup, K | 1 |
Rasmussen, F | 1 |
Dighe, S | 2 |
Blake, H | 2 |
Jeyadevan, N | 2 |
Castellano, I | 2 |
Koh, DM | 1 |
Orton, M | 2 |
Chandler, I | 1 |
Swift, I | 2 |
Brown, G | 2 |
Ichikawa, T | 1 |
Okada, M | 1 |
Kondo, H | 1 |
Sou, H | 1 |
Murakami, T | 1 |
Kanematsu, M | 1 |
Yoshikawa, S | 1 |
Shiosakai, K | 1 |
Hayakawa, A | 1 |
Awai, K | 1 |
Yoshimitsu, K | 1 |
Yamashita, Y | 1 |
Sun, H | 2 |
Xu, Y | 1 |
Yang, Q | 1 |
Wang, W | 1 |
Kaufmann, S | 1 |
Schulze, M | 1 |
Spira, D | 2 |
Horger, M | 2 |
Chung, YE | 1 |
You, JS | 1 |
Lee, HJ | 2 |
Lim, JS | 1 |
Lee, HS | 2 |
Baek, SE | 1 |
Kim, MJ | 1 |
Kim, JI | 1 |
Goo, JM | 1 |
Kim, MA | 1 |
Chung, DH | 1 |
Yanagawa, M | 1 |
Morii, E | 1 |
Hata, A | 1 |
Fujiwara, M | 1 |
Gyobu, T | 1 |
Ueda, K | 1 |
Honda, O | 1 |
Tomiyama, N | 1 |
Anemone, A | 1 |
Consolino, L | 1 |
Longo, DL | 1 |
Harri, PA | 1 |
Chung, A | 1 |
Tridandapani, S | 1 |
Nandwana, S | 1 |
Ibraheem, OO | 1 |
Cox, K | 1 |
Murphy, F | 1 |
Mittal, P | 1 |
Small, W | 1 |
Kaneoya, K | 1 |
Ueda, T | 1 |
Suito, H | 1 |
Nanazawa, Y | 1 |
Tamaru, J | 1 |
Isobe, K | 1 |
Naya, Y | 1 |
Tobe, T | 1 |
Motoori, K | 1 |
Yamamoto, S | 1 |
Rubin, GD | 1 |
Minami, M | 1 |
Ito, H | 1 |
Hata, H | 1 |
Mori, H | 1 |
Matsumoto, S | 1 |
Yamada, Y | 1 |
Kiyosue, H | 1 |
Tanoue, S | 1 |
Hongo, N | 1 |
Kashima, K | 1 |
Akashi-Tanaka, S | 1 |
Shien, T | 1 |
Tsukagoshi, S | 1 |
Funabasama, S | 1 |
Miyagawa, K | 1 |
Terada, K | 1 |
Yoshida, M | 1 |
Hojo, T | 1 |
Kinoshita, T | 1 |
Moriyama, N | 2 |
Jiang, HJ | 1 |
Zhang, ZR | 1 |
Shen, BZ | 2 |
Wan, Y | 1 |
Guo, H | 1 |
Shu, SJ | 1 |
Kim, KS | 1 |
Lee, JM | 2 |
Kim, SH | 2 |
Kim, KW | 1 |
Kim, SJ | 1 |
Cho, SH | 1 |
Han, JK | 1 |
Choi, BI | 1 |
Chen, TW | 2 |
Yang, ZG | 2 |
Wang, QL | 1 |
Li, Y | 2 |
Qian, LL | 1 |
Chen, HJ | 2 |
Qin, HY | 1 |
Sun, HR | 1 |
Li, YJ | 1 |
Chung, GE | 1 |
Lee, JH | 1 |
Yoon, JH | 1 |
Myung, SJ | 1 |
Lee, K | 1 |
Jang, JJ | 1 |
Suh, KS | 1 |
Kim, YJ | 1 |
Tang, SS | 1 |
Yao, J | 1 |
Dong, ZH | 1 |
He, D | 1 |
Castellano, E | 1 |
Koh, MU | 1 |
Orten, M | 1 |
Adam, P | 1 |
Linder, C | 1 |
Spira, SM | 1 |
Pintoffl, J | 1 |
Claussen, CD | 1 |
Stewart, EE | 1 |
Chen, X | 1 |
Schafer, PH | 1 |
Chen, Y | 1 |
Garcia, BM | 1 |
Lee, TY | 2 |
Messiou, C | 1 |
Ang, JE | 1 |
Collins, DJ | 1 |
Morgan, VA | 1 |
Mears, D | 1 |
Papadatos-Pastos, D | 1 |
Brunetto, A | 1 |
Tunariu, N | 1 |
Mann, H | 1 |
Tessier, J | 1 |
Young, H | 1 |
Ghiorghiu, D | 1 |
Marley, S | 1 |
Kaye, SB | 1 |
deBono, JS | 1 |
Leach, MO | 1 |
deSouza, NM | 1 |
Osimani, M | 1 |
Bellini, D | 1 |
Di Cristofano, C | 1 |
Palleschi, G | 1 |
Petrozza, V | 1 |
Carbone, A | 1 |
Laghi, A | 1 |
Roberts, HC | 1 |
Roberts, TP | 1 |
Dillon, WP | 1 |
Kiessling, F | 1 |
Greschus, S | 1 |
Lichy, MP | 1 |
Bock, M | 1 |
Fink, C | 1 |
Vosseler, S | 1 |
Moll, J | 1 |
Mueller, MM | 1 |
Fusenig, NE | 1 |
Traupe, H | 1 |
Semmler, W | 1 |
Iinuma, G | 1 |
Satake, M | 1 |
Miyakawa, K | 1 |
Tateishi, U | 1 |
Uchiyama, N | 1 |
Akasu, T | 1 |
Fujii, T | 1 |
Kobayashi, T | 1 |
Dromain, C | 1 |
Balleyguier, C | 1 |
Muller, S | 1 |
Mathieu, MC | 1 |
Rochard, F | 1 |
Opolon, P | 1 |
Sigal, R | 1 |
Pacella, CM | 1 |
Bizzarri, G | 1 |
Anelli, V | 1 |
Valle, D | 1 |
Fabbrini, R | 1 |
Bianchini, A | 1 |
Fenderico, P | 1 |
Rossi, Z | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
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Computed Tomography Perfusion of Colorectal Cancer in Correlation With Tumor Grade[NCT03448302] | 50 participants (Anticipated) | Observational | 2018-03-10 | Not yet recruiting | |||
Exploratory Open-Label, Non-randomised, Single Centre Methodology Study Comparing DCE-CT and DCE-MRI as Markers of Changes in Vascular Activity Mediated by a Positive Control Agent [Cediranib (Recentin™; AZD2171), a Potent Inhibitor of VEGF-driven Angioge[NCT00748891] | Phase 1 | 35 participants (Anticipated) | Interventional | 2008-08-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 trial available for iohexol and Angiogenesis, Pathologic
Article | Year |
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Advanced solid tumors treated with cediranib: comparison of dynamic contrast-enhanced MR imaging and CT as markers of vascular activity.
Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Contrast Media; Dose-Response Relations | 2012 |
30 other studies available for iohexol and Angiogenesis, Pathologic
Article | Year |
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Iodine Parameters in Triple-Bolus Dual-Energy CT Correlate With Perfusion CT Biomarkers of Angiogenesis in Renal Cell Carcinoma.
Topics: Adult; Aged; Carcinoma, Renal Cell; Contrast Media; Female; Humans; Iohexol; Kidney Neoplasms; Male; | 2020 |
Spectral CT in Lung Cancer: Usefulness of Iodine Concentration for Evaluation of Tumor Angiogenesis and Prognosis.
Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Iohexol; Lung Neoplasms; Male; Middl | 2020 |
Use of patient outcome endpoints to identify the best functional CT imaging parameters in metastatic renal cell carcinoma patients.
Topics: Blood Flow Velocity; Blood Volume; Carcinoma, Renal Cell; Contrast Media; Four-Dimensional Computed | 2018 |
Perfusion CT vascular parameters do not correlate with immunohistochemically derived microvessel density count in colorectal tumors.
Topics: Aged; Aged, 80 and over; Artifacts; Colorectal Neoplasms; Contrast Media; Female; Humans; Immunoenzy | 2013 |
Recommended iodine dose for multiphasic contrast-enhanced mutidetector-row computed tomography imaging of liver for assessing hypervascular hepatocellular carcinoma: multicenter prospective study in 77 general hospitals in Japan.
Topics: Aged; Carcinoma, Hepatocellular; Contrast Media; Dose-Response Relationship, Drug; Female; Hospitals | 2013 |
Assessment of tumor grade and angiogenesis in colorectal cancer: whole-volume perfusion CT.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Colon; Colorectal Neoplasms; Contrast Media; Female; | 2014 |
Comparison of volume perfusion computed tomography and contrast-enhanced ultrasound for assessment of therapeutic effect of transarterial chemoembolization in patients with hepatocellular carcinoma: a preliminary report.
Topics: Aged; Aged, 80 and over; Blood Volume; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Co | 2016 |
Possible Contrast Media Reduction with Low keV Monoenergetic Images in the Detection of Focal Liver Lesions: A Dual-Energy CT Animal Study.
Topics: Animals; Aortography; Contrast Media; Dose-Response Relationship, Drug; Feasibility Studies; Iohexol | 2015 |
Correlation of volumetric perfusion CT parameters with hypoxia inducible factor-1 alpha expression in a rabbit VX2 tumor model.
Topics: Animals; Cone-Beam Computed Tomography; Contrast Media; Disease Models, Animal; Hypoxia-Inducible Fa | 2016 |
Dual-energy dynamic CT of lung adenocarcinoma: correlation of iodine uptake with tumor gene expression.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aged; Aged, 80 and over; Contrast Media; ErbB Receptors; Fem | 2016 |
MRI-CEST assessment of tumour perfusion using X-ray iodinated agents: comparison with a conventional Gd-based agent.
Topics: Animals; Contrast Media; Female; Gadolinium; Heterocyclic Compounds; Image Enhancement; Iohexol; Iop | 2017 |
Extra-hepatic sarcoma metastasis surveillance in the liver: is arterial phase imaging necessary?
Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Iohexol; Liver Neoplasms; Male; Midd | 2017 |
Functional computed tomography imaging of tumor-induced angiogenesis: preliminary results of new tracer kinetic modeling using a computer discretization approach.
Topics: Adult; Aged; Angiography, Digital Subtraction; Carcinoma, Renal Cell; Computer Simulation; Contrast | 2008 |
Fibrous stroma and vascularity of pancreatic carcinoma: correlation with enhancement patterns on CT.
Topics: Adenocarcinoma; Aged; Azo Compounds; Carcinoma, Pancreatic Ductal; Coloring Agents; Contrast Media; | 2010 |
Whole-breast volume perfusion images using 256-row multislice computed tomography: visualization of lesions with ductal spread.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Ductal, Breast; Cont | 2009 |
Functional CT for assessment of early vascular physiology in liver tumors.
Topics: Animals; Blood Flow Velocity; Blood Volume; Capillary Permeability; Cineangiography; Contrast Media; | 2008 |
Image fusion in dual energy computed tomography for detection of hypervascular liver hepatocellular carcinoma: phantom and preliminary studies.
Topics: Adult; Aged; Analysis of Variance; Carcinoma, Hepatocellular; Contrast Media; Female; Humans; Iohexo | 2010 |
Whole tumour quantitative measurement of first-pass perfusion of oesophageal squamous cell carcinoma using 64-row multidetector computed tomography: correlation with microvessel density.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Contrast Media; Esophageal Neoplasms; Female; Humans; Immunoe | 2011 |
Application of CT perfusion imaging to the histological differentiation of adrenal gland tumors.
Topics: Adenoma; Adrenal Gland Neoplasms; Algorithms; Blood Volume; Contrast Media; Diagnosis, Differential; | 2012 |
Prognostic implications of tumor vascularity and its relationship to cytokeratin 19 expression in patients with hepatocellular carcinoma.
Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Chi-Square Distribution; Contrast Media; Female; Human | 2012 |
Quantitative assessment of first-pass perfusion using a low-dose method at multidetector CT in oesophageal squamous cell carcinoma: correlation with VEGF expression.
Topics: Adult; Aged; Aged, 80 and over; Blood Volume; Carcinoma, Squamous Cell; Contrast Media; Esophageal N | 2012 |
Perfusion CT to assess angiogenesis in colon cancer: technical limitations and practical challenges.
Topics: Colonic Neoplasms; Contrast Media; Feasibility Studies; Humans; Iliac Artery; Iohexol; Movement; Neo | 2012 |
Perfusion and flow extraction product as potential discriminators in untreated follicular and diffuse large B cell lymphomas using volume perfusion CT with attempt at histopathologic explanation.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Blood Flow Velocity; Blood Volume; Contrast Media; Femal | 2012 |
Effect of an angiogenesis inhibitor on hepatic tumor perfusion and the implications for adjuvant cytotoxic therapy.
Topics: Angiogenesis Inhibitors; Animals; Contrast Media; Disease Models, Animal; Immunohistochemistry; Iohe | 2012 |
Perfusion MDCT of prostate cancer: correlation of perfusion CT parameters and immunohistochemical markers of angiogenesis.
Topics: Aged; Biopsy; Contrast Media; Humans; Immunohistochemistry; Iohexol; Male; Middle Aged; Neovasculari | 2012 |
Dynamic contrast-enhanced computed tomography (CT) for quantitative estimation of microvascular permeability in human brain tumors.
Topics: Adenocarcinoma; Aged; Blood Volume; Brain Neoplasms; Capillary Permeability; Contrast Media; Female; | 2002 |
Volumetric computed tomography (VCT): a new technology for noninvasive, high-resolution monitoring of tumor angiogenesis.
Topics: Animals; Barium Sulfate; Histological Techniques; Iohexol; Iopamidol; Magnetic Resonance Imaging; Mi | 2004 |
Vascular virtual endoluminal visualization of invasive colorectal cancer on MDCT colonography.
Topics: Adult; Aged; Colonography, Computed Tomographic; Colorectal Neoplasms; Contrast Media; Female; Human | 2005 |
Evaluation of tumor angiogenesis of breast carcinoma using contrast-enhanced digital mammography.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Contrast Media; Humans; Iohexol; Mammography; Midd | 2006 |
Evaluation of the vascular pattern of hepatocellular carcinoma with dynamic computed tomography and its use in identifying optimal temporal windows for helical computed tomography.
Topics: Aged; Aorta, Abdominal; Carcinoma, Hepatocellular; Contrast Media; Evaluation Studies as Topic; Fema | 1998 |