Page last updated: 2024-10-29

iohexol and Adnexal Diseases

iohexol has been researched along with Adnexal Diseases in 2 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Adnexal Diseases: Diseases of the uterine appendages (ADNEXA UTERI) including diseases involving the OVARY, the FALLOPIAN TUBES, and ligaments of the uterus (BROAD LIGAMENT; ROUND LIGAMENT).

Research Excerpts

ExcerptRelevanceReference
"Iothalamate meglumine 60% was associated with mild inflammatory infiltrate, mucosal edema, giant cell reaction, and periovarian adhesions that were bilateral but more pronounced on the injected side."1.28Effects of contrast agents on the fallopian tube in a rabbit model. ( Eisenberg, AD; Holburn, GE; Moore, DE; Page, DL; Segars, JH; Winfield, AC, 1990)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gadelhak, B1
Tawfik, AM1
Saleh, GA1
Batouty, NM1
Sobh, DM1
Hamdy, O1
Refky, B1
Moore, DE1
Segars, JH1
Winfield, AC1
Page, DL1
Eisenberg, AD1
Holburn, GE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Can Contrast Infused Sonography Using Air Bubbles Replace Hysterosalpingogram as the Diagnostic Evaluation of Fallopian Tube Patency Following Hysteroscopic Sterilization Using Essure[NCT02628873]21 participants (Actual)Interventional2015-12-31Terminated (stopped due to Essure no longer sold in the US after Dec 2018; Sponsor requested trial be ended)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Physician Evaluation of Uterine Cavity

"Observed image of uterus (normal or not normal). Assessor commented on uterine cavity to determine whether cavity was normal versus abnormal, e.g., bicornuate uterus or any notable uterine deformity. Data were coded as normal' or not normal." (NCT02628873)
Timeframe: At time of HyCoSy procedure

InterventionParticipants (Count of Participants)
Arm 1 (HyCoSy Followed by HSG)13
Arm 2 (HSG Followed by HyCoSy)6

Fallopian Tube Patency - HyCoSy vs HSG

Observed flow of fluid/bubbles through fallopian tubes. (NCT02628873)
Timeframe: At time of procedure

,
Interventionfallopian tubes observed to be closed (Count of Units)
Number of tubes closed per first procedureNumber of tubes closed per second procedure
Arm 1 (HyCoSy Followed by HSG)2425
Arm 2 (HSG Followed by HyCoSy)1212

Pain Scores

Patient reported pain scale score on visual pain scale (rated 0 for no pain to 10 for severe pain with corresponding faces) (NCT02628873)
Timeframe: At time of procedures

,
Interventionunits on a scale (Mean)
HSG post procedure pain scoreHyCoSy post procedure pain score
Arm 1 (HyCoSy Followed by HSG)1.42.4
Arm 2 (HSG Followed by HyCoSy)1.82.3

Other Studies

2 other studies available for iohexol and Adnexal Diseases

ArticleYear
Extended abdominopelvic MRI versus CT at the time of adnexal mass characterization for assessing radiologic peritoneal cancer index (PCI) prior to cytoreductive surgery.
    Abdominal radiology (New York), 2019, Volume: 44, Issue:6

    Topics: Adnexal Diseases; Contrast Media; Cytoreduction Surgical Procedures; Female; Humans; Iohexol; Magnet

2019
Effects of contrast agents on the fallopian tube in a rabbit model.
    Radiology, 1990, Volume: 176, Issue:3

    Topics: Adnexa Uteri; Adnexal Diseases; Animals; Contrast Media; Ethiodized Oil; Fallopian Tube Diseases; Fa

1990