Page last updated: 2024-10-29

iohexol and Acute Kidney Injury

iohexol has been researched along with Acute Kidney Injury in 146 studies

Iohexol: An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
iohexol : A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
"This study investigated the effect and mechanism of rosiglitazone on a rat model with contrast-induced acute kidney injury (CI-AKI)."9.51Rosiglitazone Alleviates Contrast-Induced Acute Kidney Injury in Rats via the PPAR ( Chen, E; Huang, J; Wu, J; Zheng, X, 2022)
"Edaravone was administered for two weeks before the induction of CI-AKI."5.72Exploring the effects of edaravone in rats with contrast-induced acute kidney injury. ( Al Tahrawi, AY; Alshogran, OY; Nusair, SD, 2022)
"Iohexol was used to act on HK-2 cells to establish a renal tubular cell pyroptosis model; and the signal pathway genes were silenced, cytokines were detected by enzyme-linked immunosorbent assay (ELISA), and cell viability, gene expression, and protein expression were evaluated by double fluorescence staining and flow cytometry."5.72Baicalin Alleviates Contrast-Induced Acute Kidney Injury Through ROS/NLRP3/Caspase-1/GSDMD Pathway-Mediated Proptosis in vitro. ( Huang, D; Li, Y; Wang, J; Yu, C, 2022)
"This study investigated the effect and mechanism of rosiglitazone on a rat model with contrast-induced acute kidney injury (CI-AKI)."5.51Rosiglitazone Alleviates Contrast-Induced Acute Kidney Injury in Rats via the PPAR ( Chen, E; Huang, J; Wu, J; Zheng, X, 2022)
" Two children (2/42) had decreased cyst C eGFR, for one of whom iohexol clearance confirmed mildly decreased GFR."4.31Kidney outcomes in early adolescence following perinatal asphyxia and hypothermia-treated hypoxic-ischaemic encephalopathy. ( Bárány, P; Blennow, M; Chromek, M; Diaz Ruiz, S; Kublickiene, K; Robertsson Grossmann, K; Vishnevskaya, L, 2023)
" Possible reasons for the diverse impact of blood pressure on the propensity to develop acute kidney failure after iodine-based but not gadolinium-based enhancement imaging are discussed."3.91Negligible Risk of Acute Renal Failure Among Hospitalized Patients After Contrast-Enhanced Imaging With Iodinated Versus Gadolinium-Based Agents. ( Gorelik, Y; Heyman, SN; Khamaisi, M; Yaseen, H, 2019)
" In our study, dehydration duration and the iohexol dosage were found to be the two most important factors to develop a rat CIN model."3.91A novel rat model of contrast-induced nephropathy based on dehydration. ( Chen, LH; Cheng, WJ; Hu, C; Li, DY; Liu, K; Wang, JL; Xie, YL; Yin, WJ; Zhou, G; Zhou, LY; Zuo, SR; Zuo, XC, 2019)
"Kidney Disease: Improved Global Outcomes acute kidney injury criteria were fulfilled in 22 patients (nephrectomy = 5, surgery = 4, and acute kidney injury = 13); continuous infusion of low-dose Iohexol demonstrated acute kidney injury in 29 patients (nephrectomy = 10, surgery = 8, acute kidney injury = 11)."3.88Continuous Infusion of Low-Dose Iohexol Measures Changing Glomerular Filtration Rate in Critically Ill Patients. ( Chis Ster, I; Dalton, RN; Dixon, JJ; Lane, K; MacPhee, IAM; Philips, BJ; Turner, C, 2018)
"The study was processed to investigate the effect of astaxanthin (AST; 3,3-dihydroxybeta, beta-carotene-4,4-dione) on the acute kidney injury induced by iohexol and the relationship with SIRT1/FOXO3a signal pathway."3.88Astaxanthin attenuates contrast agent-induced acute kidney injury in vitro and in vivo via the regulation of SIRT1/FOXO3a expression. ( Chen, J; Gao, D; Li, W; Liu, N; Zheng, D, 2018)
"The application of iodinated contrast medium has become a risk factor for metformin-associated lactic acidosis (MALA), which leads to the accumulation of metformin in vivo is one of the principal reasons for MALA."3.88Involvement of organic cation transporter 2 in the metformin-associated increased lactate levels caused by contrast-induced nephropathy. ( Dai, Y; Huo, X; Liu, K; Liu, Z; Ma, X; Meng, Q; Peng, J; Sun, H; Wang, C; Yang, S, 2018)
"Rats received nitric oxide synthase inhibitor L-NAME (10 mg/kg) and cyclooxygenase inhibitor indomethacin (10 mg/kg) to induce the risk for developing iodinated contrast-induced acute kidney injury before receiving one of the interventions: NAC, furosemide, or placebo."3.80Efficacy of preventive interventions for iodinated contrast-induced acute kidney injury evaluated by intrarenal oxygenation as an early marker. ( Franklin, T; Li, LP; Lu, J; Papadopoulou, MV; Prasad, PV; Solomon, R; Thacker, J; Zhou, Y, 2014)
"Contrast induced acute kidney injury is one of the most frequent causes of hospital acquired acute kidney injury."2.77Efficacy of vitamin E and N-acetylcysteine in the prevention of contrast induced kidney injury in patients with chronic kidney disease: a double blind, randomized controlled trial. ( Binder, C; Jaberi, A; Kitzler, TM; Kotanko, P; Petnehazy, E; Rehak, P; Sendlhofer, G; Stacher, R, 2012)
" The secondary endpoints are absolute and relative increases in sCr of at least 50%, thrombolysis in myocardial infarction (TIMI) perfusion grade, and major adverse cardiac events at 1, 6, and 12 months."2.75The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study. ( Angioli, P; Bolognese, L; Carrera, A; Ducci, K; Falsini, G; Grotti, S; Liistro, F; Limbruno, U; Picchi, A; Pierli, C, 2010)
"Eighty-two patients with chronic renal failure, referred for coronary angiography, were assigned randomly to receive either normal saline intravenously and prophylactic hemodialysis (dialysis group; n = 42) or fluid supplement only (control group; n = 40)."2.73Renal protection for coronary angiography in advanced renal failure patients by prophylactic hemodialysis. A randomized controlled trial. ( Chen, CL; Chou, KJ; Chung, HM; Fang, HC; Hsu, CY; Lee, PT; Liu, CP; Mar, GY, 2007)
"Iodixanol was cost-effective compared with iohexol, with both lower costs and better effects related to fewer adverse drug reactions."2.71Cost-effectiveness of iodixanol in patients at high risk of contrast-induced nephropathy. ( Aspelin, P; Aubry, P; Fransson, SG; Lundkvist, J; Strasser, R; Willenbrock, R, 2005)
" Clinically severe adverse renal events were uncommon (N = 15) and did not differ in incidence between contrast groups (iohexol N = 6; diatrizoate N = 9)."2.68Nephrotoxicity of ionic and nonionic contrast media in 1196 patients: a randomized trial. The Iohexol Cooperative Study. ( Cohen, MB; Goldfarb, S; Halpern, EF; Hill, JA; Ludbrook, PA; Murphy, MJ; Rudnick, MR; VanFossen, DB; Wexler, L; Winniford, M, 1995)
"Pretreatment with nitrendipine did not reduce enzyme excretion, although AAP levels were lower in general in the group assigned to the 20-mg dose."2.68Dose effect of nitrendipine on urinary enzymes and microproteins following non-ionic radiocontrast administration. ( Artero, M; Carraro, M; Cova, M; Faccini, L; Grotto, M; Mancini, W; Stacul, F, 1996)
"Theophylline levels were within the therapeutic range in patients of the theophylline group during and four hours after CM application (59."2.67Adenosine antagonist theophylline prevents the reduction of glomerular filtration rate after contrast media application. ( Bohle, A; Duda, SH; Erley, CM; Huppert, PE; Koehler, J; Osswald, H; Risler, T; Schlepckow, S; Strohmaier, WL, 1994)
"Contrast media can cause acute renal failure by direct toxic effects on the tubular cells and kidney ischemia."2.48Cost-effectiveness of iso- versus low-osmolality contrast media in outpatients with high risk of contrast medium-induced nephropathy. ( Chicaíza-Becerra, LA; Gamboa, Ó; García-Molina, M, 2012)
"Iohexol and ox-LDL were used alone or in combination to treat HK-2 cells."1.91Ox-LDL aggravates contrast-induced injury of renal tubular epithelial cells. ( Chen, S; Lv, M; Tan, J; Yang, D; Yang, X, 2023)
" Compared to the control, rats that received vancomycin had numerically lower GFRs after drug dosing on day 3."1.91Iohexol-Measured Glomerular Filtration Rate and Urinary Biomarker Changes between Vancomycin and Vancomycin Plus Piperacillin-Tazobactam in a Translational Rat Model. ( Barreto, EF; Chang, J; Lesnicki, E; Marianski, S; Pais, GM; Scheetz, MH; Valdez, K, 2023)
"Edaravone was administered for two weeks before the induction of CI-AKI."1.72Exploring the effects of edaravone in rats with contrast-induced acute kidney injury. ( Al Tahrawi, AY; Alshogran, OY; Nusair, SD, 2022)
"Iohexol was used to act on HK-2 cells to establish a renal tubular cell pyroptosis model; and the signal pathway genes were silenced, cytokines were detected by enzyme-linked immunosorbent assay (ELISA), and cell viability, gene expression, and protein expression were evaluated by double fluorescence staining and flow cytometry."1.72Baicalin Alleviates Contrast-Induced Acute Kidney Injury Through ROS/NLRP3/Caspase-1/GSDMD Pathway-Mediated Proptosis in vitro. ( Huang, D; Li, Y; Wang, J; Yu, C, 2022)
"Contrast-induced acute kidney injury is a prevalent cause of renal failure, and the noninvasive tools to monitor its progress are lacking."1.48Application of noninvasive functional imaging to monitor the progressive changes in kidney diffusion and perfusion in contrast-induced acute kidney injury rats at 3.0 T. ( Chen, W; Dong, Y; Guo, B; Lian, Z; Liu, J; Ouyang, F; Zhang, B; Zhang, S, 2018)
"A total of 2563 patients diagnosed with STEMI and underwent primary pPCI were retrospectively included in the study."1.46Platelet-to-Lymphocyte Ratio Predicts Contrast-Induced Acute Kidney Injury in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. ( Akdeniz, E; Alper, AT; Bozbay, M; Eren, M; Gumusdag, A; Guvenc, TS; Guzelburc, O; Hayiroglu, MI; Kalenderoglu, K; Oz, A; Tanik, O; Tekkesin, AI; Ugur, M; Velibey, Y, 2017)
"Inclusion criteria were STEMI patients taken for cardiac catheterization, excluding patients receiving hemodialysis due to end-stage renal disease (ESRD)."1.43The incidence and significance of acute kidney injury following emergent contrast administration in patients with STEMI and stroke. ( Allen, BR; Elie, MC; Marchick, MR; Shuster, JJ; Weeks, EC, 2016)
"Contrast-induced acute renal injury (CI-AKI) has become a common cause of hospital-acquired renal failure."1.43Salvianolic Acid B Prevents Iodinated Contrast Media-Induced Acute Renal Injury in Rats via the PI3K/Akt/Nrf2 Pathway. ( Jiachang, H; Nana, S; Shaopeng, L; Ting, Z; Tongqiang, L; Xialian, X; Xiaofang, Y; Xiaoqiang, D, 2016)
" ARF was induced by the subcutaneous administration of cisplatin (5 mg/kg); IoCl and InCl were determined simultaneously, and plasma creatinine (pCreat) dosage was measured colorimetrically."1.42Iohexol clearance for determination of glomerular filtration rate in rats induced to acute renal failure. ( Câmara, NO; Mastroianni-Kirsztajn, G; Nishida, SK; Passos, MT; Shimizu, MH, 2015)
"More necrosis was present after incubation with iohexol and iopamidol than after incubation with equal concentrations of iodixanol."1.40Exposure to low- vs iso-osmolar contrast agents reduces NADPH-dependent reactive oxygen species generation in a cellular model of renal injury. ( Cafiero, C; Gesualdo, L; Grandaliano, G; Montemurno, E; Netti, GS; Prattichizzo, C; Ranieri, E; Rascio, F; Simone, S; Stallone, G, 2014)
"Atorvastatin (ATO) was administered intragastrically at the dose of 5, 10 and 30mg/kg/d in different groups, respectively, for 5 days before iopromide injection."1.40Atorvastatin ameliorates contrast medium-induced renal tubular cell apoptosis in diabetic rats via suppression of Rho-kinase pathway. ( Cai, W; Cao, Y; Chen, X; Li, S; Ma, W; Su, J; Wang, F; Zou, W, 2014)
"In patients with liver cirrhosis a urine protein:creatinine ratio >30 predicts AKI."1.39Predicting the development of acute kidney injury in liver cirrhosis--an analysis of glomerular filtration rate, proteinuria and kidney injury biomarkers. ( Auzinger, G; Bernal, W; Bruce, M; Dew, T; Heneghan, MA; McPhail, MJ; Moore, K; Musto, R; O'Grady, J; Ostermann, M; Sherwood, R; Slack, AJ; Wendon, JA, 2013)
"upon iodixanol injection was reduced almost to the level of iopromide when injecting iodixanol/mannitol (iopromide: 289 ± 68 HU vs iodixanol/mannitol: 343 ± 68 HU)."1.38The osmolality of nonionic, iodinated contrast agents as an important factor for renal safety. ( Ellinghaus, P; Ernst, R; Jost, G; Lengsfeld, P; Lenhard, DC; Pietsch, H; Sieber, MA, 2012)
"The odds ratio of acute kidney failure on day 5 was 0."1.38Effect of renin-angiotensin-aldosterone system blockade therapy on incidence of contrast-induced nephropathy in patients with chronic kidney disease. ( Ghahramani, N; Lapsiwala, A; Parhizgar, A; Saadulla, L; Spatz, C, 2012)
"Most patients with HCC have coexisting liver cirrhosis (LC) at the time of diagnosis."1.37Incidence and risk factors for radiocontrast-induced nephropathy in patients with hepatocellular carcinoma undergoing transcatheter arterial chemoembolization. ( Bae, EJ; Chang, SH; Cho, HS; Kang, Y; Kim, HJ; Park, DJ; Seo, JW, 2011)
"Postoperative acute renal failure (ARF) is not uncommon after cardiac surgery and after angiography."1.35Influence of the timing of cardiac catheterization and the amount of contrast media on acute renal failure after cardiac surgery. ( Ballotta, A; Bossone, E; Conti, D; De Benedetti, D; Kandil, H; Kunkl, A; Mehta, RH; Mollichelli, N; Ranucci, M, 2008)
"The HOCM, diatrizoate, was more toxic to rat kidneys than the LOCM iohexol; PLA2, LPO and calcium load played a role in producing renal function impairment induced by diatrizoate meglumine; amlodipine protected the renal tissue from nephrotoxicity induced by diatrizoate."1.31Nephrotoxicity of high- and low-osmolar contrast media. The protective role of amlodipine in a rat model. ( Duan, SB; Liu, FY; Liu, RH; Luo, JA; Peng, YM; Wu, HW; Yang, XL, 2000)

Research

Studies (146)

TimeframeStudies, this research(%)All Research%
pre-19903 (2.05)18.7374
1990's14 (9.59)18.2507
2000's27 (18.49)29.6817
2010's79 (54.11)24.3611
2020's23 (15.75)2.80

Authors

AuthorsStudies
Wang, L2
Huang, S2
Zhu, T1
Ge, X1
Pei, C1
Hong, G1
Han, L1
Nabi, MM1
Sakamoto, T1
Mamun, MA1
Islam, A1
Waliullah, ASM1
Aramaki, S1
Hasan, MM1
Ema, S1
Kato, A1
Takahashi, Y1
Kahyo, T1
Setou, M1
Sato, T1
Smeets, NJL1
Teunissen, EMM1
van der Velden, K1
van der Burgh, MJP1
Linders, DE1
Teesselink, E1
Moes, DAR1
Tøndel, C1
Ter Heine, R1
van Heijst, A1
Schreuder, MF1
de Wildt, SN1
Wu, J2
Shen, J1
Wang, W1
Jiang, N2
Jin, H1
Che, X1
Ni, Z2
Fang, Y4
Mou, S2
Robertsson Grossmann, K1
Vishnevskaya, L1
Diaz Ruiz, S1
Kublickiene, K1
Bárány, P1
Blennow, M1
Chromek, M1
Alshogran, OY1
Al Tahrawi, AY1
Nusair, SD1
Li, Y2
Wang, J1
Huang, D1
Yu, C1
Liu, K4
Hu, C2
Yin, W1
Zhou, L1
Gu, X1
Zuo, X1
Huang, J1
Chen, E2
Zheng, X1
Yang, D2
Yang, X2
Chen, S2
Lv, M1
Tan, J1
Chang, J1
Pais, GM1
Marianski, S1
Valdez, K1
Lesnicki, E1
Barreto, EF1
Scheetz, MH1
Chen, HY1
Wu, YH1
Wei, CY1
Liao, ZY1
Wu, HT1
Chen, YC1
Pang, JS1
Zhou, LY2
Yin, WJ2
Xie, YL2
Wang, JL2
Zuo, SR2
Tang, ZY1
Wu, YF1
Zuo, XC2
Kalogirou, TE1
Meditskou, S1
Davidopoulou, S1
Savvas, I1
Pitoulias, AG1
Pitoulias, GA1
Yang, KJ1
Kim, JH1
Chang, YK1
Park, CW1
Kim, SY1
Hong, YA2
Diprose, WK1
Sutherland, LJ1
Wang, MTM1
Barber, PA1
Li, DY2
Cheng, WJ2
Chen, LH1
Zhou, G1
Lin, HH1
Lee, TS1
Lin, SJ1
Yeh, YC1
Lu, TM1
Hsu, CP1
Chen, F1
Lu, J3
Xiao, B1
Chen, H1
Pei, W1
Jin, Y1
Wang, M1
Zhang, J1
Liu, F1
Gu, G1
Cui, W1
Liu, C1
Hu, YH1
Han, Y1
Wang, YB1
Zhang, Y1
Zhang, XQ1
He, DF1
Ren, HM1
Liu, YK1
Wang, HY1
Tan, T1
Lin, PH1
Li, HC1
Rovin, BH1
Ma, JJ1
Zeng, CY1
Wang, Z1
Liu, H1
Meng, H2
Zhang, D1
Xu, J1
Ma, L1
Fu, P1
Suh, K1
Kellum, JA1
Kane-Gill, SL1
Annamalai, C1
Seth, R1
Viswanathan, P1
Desgrouas, M1
Merdji, H1
Bretagnol, A1
Barin-Le Guellec, C2
Halimi, JM2
Ehrmann, S2
Salmon Gandonnière, C1
Shibata, S1
Moniwa, N1
Kuno, A1
Kimura, A1
Ohwada, W1
Sugawara, H1
Gocho, Y1
Tanaka, M1
Yano, T1
Furuhashi, M1
Tanno, M1
Miki, T1
Miura, T1
Chen, G1
Liu, B1
Li, H2
Liu, J3
Mai, Z1
Zhou, C1
Sun, G1
Guo, Z1
Lei, L1
Zhang, L1
Li, M1
Tan, N2
Liao, Y1
Chen, J3
Liu, Y2
Rowe, ES2
Rowe, VD2
Hunter, J2
Gralinski, MR2
Neves, LA1
Rollins, K1
Noorani, A1
Janeckova, L1
Jones, T1
Griffiths, M1
Baker, MP1
Boyle, JR1
Zhang, B1
Dong, Y1
Guo, B1
Chen, W1
Ouyang, F1
Lian, Z1
Zhang, S1
Spasojević-Dimitrijeva, B1
Kotur-Stevuljević, J1
Đukić, M1
Paripović, D1
Miloševski-Lomić, G1
Spasojević-Kalimanovska, V1
Pavićević, P1
Mitrović, J1
Kostić, M1
Takahashi, EA1
Kallmes, DF6
Fleming, CJ1
McDonald, RJ6
McKusick, MA1
Bjarnason, H1
Harmsen, WS1
Misra, S1
Düzel, B1
Emren, SV1
Berilgen, R1
Hudzik, B1
Szkodziński, J1
Korzonek-Szlacheta, I1
Wilczek, K1
Gierlotka, M1
Lekston, A1
Zubelewicz-Szkodzińska, B1
Gąsior, M1
Dixon, JJ1
Lane, K1
Dalton, RN1
Turner, C1
MacPhee, IAM1
Chis Ster, I1
Philips, BJ1
Jeong, BY1
Lee, HY1
Park, CG1
Kang, J1
Yu, SL1
Choi, DR1
Han, SY1
Park, MH1
Cho, S1
Lee, SY1
Hwang, WM1
Yun, SR1
Ryu, HM1
Oh, EJ1
Park, SH1
Kim, YL1
Yoon, SH1
Liu, N1
Gao, D1
Li, W2
Zheng, D1
Lei, R1
Zhao, F2
Tang, CY2
Luo, M2
Yang, SK1
Cheng, W2
Li, XW2
Duan, SB3
McDonald, JS5
Steckler, EM1
Katzberg, RW4
Williamson, EE5
Cernigliaro, JG1
Hamadah, AM1
Gharaibeh, K1
Leung, N1
Tran, CL1
Kolbe, AB1
Mukherjee, D1
Nedungadi, S1
Yang, S1
Dai, Y1
Liu, Z1
Wang, C1
Meng, Q1
Huo, X1
Sun, H1
Ma, X1
Peng, J1
Azzalini, L1
Vilca, LM1
Lombardo, F1
Poletti, E1
Laricchia, A1
Beneduce, A1
Maccagni, D1
Demir, OM1
Slavich, M1
Giannini, F1
Carlino, M2
Margonato, A1
Cappelletti, A1
Colombo, A2
Zhang, Z1
Shao, X1
Gu, L1
Li, S2
Lin, Q1
He, Y1
Zhang, M1
Zhou, W1
McCullough, PA2
Todoran, TM1
Brilakis, ES1
Ryan, MP1
Gunnarsson, C1
Gorelik, Y1
Yaseen, H1
Heyman, SN1
Khamaisi, M1
Ravn, B1
Rimes-Stigare, C1
Bell, M1
Hansson, M1
Hansson, LO1
Martling, CR1
Larsson, A1
Mårtensson, J1
Hu, Z1
Shang, T1
Huang, R1
Li, Q1
Zheng, P1
Wang, H1
Xie, P1
Slack, AJ1
McPhail, MJ1
Ostermann, M1
Bruce, M1
Sherwood, R1
Musto, R1
Dew, T1
Auzinger, G1
Bernal, W1
O'Grady, J1
Heneghan, MA1
Moore, K1
Wendon, JA1
Lele, SS1
Mukhopadhyay, BN1
Mardikar, MM1
Patel, TA1
Vasavada, AK1
Banker, DN1
Kapasi, KD1
Chauhan, VC1
Chawla, KC1
Raju, SR1
Hiremath, SS1
Chinchole, SS1
Rajapurkar, MM1
Limbruno, U3
Picchi, A3
Micheli, A1
Calabria, P1
Cortese, B1
Brizi, G1
Severi, S1
De Caterina, R1
Murakami, R1
Kumita, S1
Hayashi, H1
Sugizaki, K1
Okazaki, E1
Kiriyama, T1
Hakozaki, K1
Tani, H1
Miki, I1
Takeda, M1
Miao, Y1
Zhong, Y1
Yan, H1
Wang, BY1
Jin, J1
Netti, GS1
Prattichizzo, C1
Montemurno, E1
Simone, S1
Cafiero, C1
Rascio, F1
Stallone, G1
Ranieri, E1
Grandaliano, G1
Gesualdo, L1
Beyazal, H1
Caliskan, Z1
Utaç, C1
Sun, S1
Zhang, T2
Nie, P1
Hu, L1
Yu, Y1
Cui, M1
Cai, Z1
Shen, L1
He, B2
Su, J1
Zou, W1
Cai, W1
Chen, X1
Wang, F1
Ma, W1
Cao, Y1
Li, LP2
Zhou, Y2
Papadopoulou, MV2
Franklin, T2
Bokhary, U1
Solomon, R3
Sen, A1
Prasad, PV2
Li, WH1
Qian, WH1
Liu, JL1
Xu, TD1
Zhu, H1
He, HY1
Thacker, J1
Wang, YC1
Tang, A1
Chang, D1
Zhang, SJ1
Ju, S1
Hwang, YJ1
Hyun, MC1
Choi, BS1
Chun, SY1
Cho, MH1
Chua, HR1
Horrigan, M1
Mcintosh, E1
Bellomo, R1
Carter, RE3
Hartman, RP3
Mariani, J1
Guedes, C1
Soares, P1
Zalc, S1
Campos, CM1
Lopes, AC1
Spadaro, AG1
Perin, MA1
Filho, AE1
Takimura, CK1
Ribeiro, E1
Kalil-Filho, R1
Edelman, ER1
Serruys, PW1
Lemos, PA1
Liu, T2
Liu, S1
Yu, X1
Zhang, H2
Liang, M1
Ding, X2
Liu, TQ1
Luo, WL1
Tan, X1
Yu, XF1
Cai, JR1
Ding, XQ1
Passos, MT1
Nishida, SK1
Câmara, NO1
Shimizu, MH1
Mastroianni-Kirsztajn, G1
Liu, YH1
Chen, JY1
Zhou, YL1
Luo, JF1
Yu, DQ1
Li, LW1
Li, HL1
Ye, P1
Ran, P1
Mirrakhimov, AE1
Mirrakhimov, EM1
Shema-Didi, L1
Kristal, B1
Eizenberg, S1
Marzuq, N1
Sussan, M1
Feldman-Idov, Y1
Ofir, P1
Atar, S1
Ko, GJ1
Bae, SY1
Pyo, HJ1
Kwon, YJ1
Gramberg, MC1
Penne, EL1
Marchick, MR1
Allen, BR1
Weeks, EC1
Shuster, JJ1
Elie, MC1
Arayan, A1
Nigogosyan, MA1
Van Every, MJ1
Wu, P1
Zhao, Y1
Xu, Z1
Wang, ZM1
Li, C1
Yang, Z1
Salmon-Gandonnière, C1
Benz-de Bretagne, I1
Mercier, E1
Joret, A1
Biswas, S1
Mosher, G1
Insisienmay, L1
Ozias, MK1
Barnett, JS1
Fananapazir, G1
Troppmann, C1
Corwin, MT1
Nikpour, AM1
Naderi, S1
Lamba, R1
Tongqiang, L1
Shaopeng, L1
Xiaofang, Y1
Nana, S1
Xialian, X1
Jiachang, H1
Ting, Z1
Xiaoqiang, D1
Velibey, Y1
Oz, A1
Tanik, O1
Guvenc, TS1
Kalenderoglu, K1
Gumusdag, A1
Akdeniz, E1
Bozbay, M1
Tekkesin, AI1
Guzelburc, O1
Hayiroglu, MI1
Alper, AT1
Ugur, M1
Eren, M1
Sun, SQ1
Ding, D1
Zhang, WF1
Wang, XL1
Sun, Z1
Hu, LH1
Qin, SY1
Shen, LH1
Goic, JB1
Koenigshof, AM1
McGuire, LD1
Klinger, AC1
Beal, MW1
Barbieri, L1
Verdoia, M1
Nardin, M1
Marino, P1
Suryapranata, H1
De Luca, G1
Hu, J1
Chen, R1
Jia, P1
Song, N1
Xu, X1
Ji, J1
Kurtul, A1
Yarlioglues, M1
Duran, M1
Matsunami, T1
Hino, K1
Dosho, R1
Miyatake, S1
Ebisu, G1
Kuwatsuru, R1
Nie, B1
Li, YF1
Cao, Z1
Yang, Q1
Zhao, YX1
Guo, YH1
Zhou, YJ1
Heinrich, MC1
Häberle, L1
Müller, V1
Bautz, W1
Uder, M1
Chuang, FR1
Chen, TC1
Wang, IK1
Chuang, CH1
Chang, HW1
Ting-Yu Chiou, T1
Cheng, YF1
Lee, WC1
Chen, WC1
Yang, KD1
Lee, CH1
Agrawal, V1
Swami, A1
Kosuri, R1
Alsabbagh, M1
Agarwal, M1
Samarapungavan, D1
Rocher, LL1
Capasso, P1
Weisbord, SD1
Vasheghani-Farahani, A1
Sadigh, G1
Kassaian, SE1
Khatami, SM1
Fotouhi, A1
Razavi, SA1
Mansournia, MA1
Yamini-Sharif, A1
Amirzadegan, A1
Salarifar, M1
Sadeghian, S1
Davoodi, G1
Borumand, MA1
Esfehani, FA1
Darabian, S1
Bolognese, L2
Falsini, G2
Grotti, S2
Liistro, F2
Carrera, A2
Angioli, P2
Ducci, K2
Pierli, C2
Trivedi, H1
Foley, WD1
Serafin, Z1
Karolkiewicz, M1
Gruszka, M1
Strózecki, P1
Lasek, W1
Odrowaz-Sypniewska, G1
Manitius, J1
Beuth, W1
Wi, J1
Ko, YG1
Kim, JS1
Kim, BK1
Choi, D1
Ha, JW1
Hong, MK1
Jang, Y1
Cho, HS1
Seo, JW1
Kang, Y1
Bae, EJ1
Kim, HJ1
Chang, SH1
Park, DJ1
Schwenke, C1
LaBounty, TM1
Shah, M1
Raman, SV1
Lin, FY1
Berman, DS1
Min, JK1
Kitzler, TM1
Jaberi, A1
Sendlhofer, G1
Rehak, P1
Binder, C1
Petnehazy, E1
Stacher, R1
Kotanko, P1
Lenhard, DC1
Pietsch, H1
Sieber, MA1
Ernst, R1
Lengsfeld, P1
Ellinghaus, P1
Jost, G1
Spatz, C1
Saadulla, L1
Lapsiwala, A1
Parhizgar, A1
Ghahramani, N1
Chicaíza-Becerra, LA1
García-Molina, M1
Gamboa, Ó1
Ludwig, U1
Connemann, J1
Keller, F1
Emch, TM1
Haller, NA1
MacNeill, BD1
Harding, SA1
Bazari, H1
Patton, KK1
Colon-Hernadez, P1
DeJoseph, D1
Jang, IK1
Rashid, ST1
Salman, M1
Myint, F1
Baker, DM1
Agarwal, S1
Sweny, P1
Hamilton, G1
Aspelin, P1
Aubry, P1
Fransson, SG1
Strasser, R1
Willenbrock, R1
Lundkvist, J1
Hsieh, YC1
Ting, CT1
Liu, TJ1
Wang, CL1
Chen, YT1
Lee, WL1
Mueller, C1
Seidensticker, P1
Buettner, HJ1
Perruchoud, AP1
Staub, D1
Christ, A1
Buerkle, G1
Briguori, C1
Airoldi, F1
Morici, N1
Sangiorgi, GM1
Violante, A1
Focaccio, A1
Montorfano, M1
Condorelli, G1
Ricciardelli, B1
Kwak, HS1
Lee, YH1
Han, YM1
Jin, GY1
Kim, W1
Chung, GH1
Hocher, B1
Lee, HT1
Jan, M1
Bae, SC1
Joo, JD1
Goubaeva, FR1
Yang, J1
Kim, M1
Valente, S1
Lazzeri, C1
Giglioli, C1
Margheri, M1
Comeglio, M1
Nicolaci, L1
Chechi, T1
Gensini, GF1
Poletti, PA1
Saudan, P1
Platon, A1
Mermillod, B1
Sautter, AM1
Vermeulen, B1
Sarasin, FP1
Becker, CD1
Martin, PY1
Lee, PT1
Chou, KJ1
Liu, CP1
Mar, GY1
Chen, CL1
Hsu, CY1
Fang, HC1
Chung, HM1
Tejedor-Jorge, A1
Bouzas-Mosquera, A1
Vázquez-Rodríguez, JM1
Calviño-Santos, R1
Peteiro-Vázquez, J1
Flores-Ríos, X1
Marzoa-Rivas, R1
Piñón-Esteban, P1
Aldama-López, G1
Salgado-Fernández, J1
Vázquez-González, N1
Castro-Beiras, A1
Möckel, M1
Radovic, M1
Kühnle, Y1
Combé, V1
Waigand, J1
Schröder, S1
Dietz, R1
Frei, U1
Eckardt, KU1
Ranucci, M1
Ballotta, A1
Kunkl, A1
De Benedetti, D1
Kandil, H1
Conti, D1
Mollichelli, N1
Bossone, E1
Mehta, RH1
Wiemer, M1
Kreuzpaintner, G1
Lauer, B1
Kiefel, V1
Schultheiss, HP1
Horstkotte, D1
Strauer, BE1
Rudnick, MR1
Goldfarb, S1
Wexler, L1
Ludbrook, PA1
Murphy, MJ1
Halpern, EF1
Hill, JA1
Winniford, M1
Cohen, MB1
VanFossen, DB1
Erley, CM1
Duda, SH1
Schlepckow, S1
Koehler, J1
Huppert, PE1
Strohmaier, WL1
Bohle, A1
Risler, T1
Osswald, H1
Touati, C1
Idee, JM1
Deray, G1
Santus, R1
Balut, C1
Beaufils, H1
Jouanneau, C1
Bourbouze, R1
Doucet, D1
Bonnemain, B1
Nikonoff, T1
Skau, T1
Berglund, J1
Nyberg, P2
Spångberg-Viklund, B2
Larsson, R2
Carraro, M1
Mancini, W1
Artero, M1
Stacul, F1
Grotto, M1
Cova, M1
Faccini, L1
Liss, P2
Nygren, A2
Erikson, U1
Ulfendahl, HR1
Liu, FY1
Luo, JA1
Wu, HW1
Liu, RH1
Peng, YM1
Yang, XL1
Thomsen, HS1
Pettersson, G1
Towart, R1
Grant, D1
Thyberg, K1
Golman, K1
Spångberg, A1
Tervahartiala, P1
Kivisaari, L1
Kivisaari, R1
Virtanen, I1
Standertskjöld-Nordenstam, CG1
Love, L1
Olson, MC1
Parvez, Z1
Ramamurthy, S1
Patel, NB1
Moncada, R1
Campbell, DR1
Flemming, BK1
Mason, WF1
Jackson, SA1
Hirsch, DJ1
MacDonald, KJ1
Taliercio, CP1
McCallister, SH1
Holmes, DR1
Ilstrup, DM1
Vlietstra, RE1
Gomes, AS1
Lois, JF1
Baker, JD1
McGlade, CT1
Bunnell, DH1
Hartzman, S1
Elliott, C1
Reger, M1

Clinical Trials (18)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Measuring the Plasma Clearance of Iohexol to Estimate Glomerular Filtration Rate in Intensive Care Unit Patients: Preliminary Feasibility Study[NCT02050269]Phase 3100 participants (Actual)Interventional2014-01-31Completed
Contrast-inDuced nephRotoxicity as Assessed by the Cystatin-modified KIdney Load-to-DAmage RElationship[NCT01908309]Early Phase 1150 participants (Actual)Interventional2013-04-30Completed
Functional MRI-based Assessment of Terlipressin vs. Octreotide on Renal Function in Cirrhotic Patients With Acute Variceal Bleeding (CHESS1903): A Multicenter, Single-blind, Randomised Controlled Trial[NCT04028323]Phase 460 participants (Anticipated)Interventional2019-07-16Recruiting
Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease (ENRICH): A Randomized Controlled Trial[NCT05283512]254 participants (Anticipated)Interventional2022-04-20Recruiting
Renal Insufficiency Following Contrast Media Administration Trial IV: Contrast Media Volume Control for Limiting Contrast-Induced Acute Kidney in Acute Coronary Syndrome.[NCT04714736]522 participants (Anticipated)Interventional2020-02-10Recruiting
Minimizing cOntrast utiliZAtion With IVUS Guidance in coRonary angioplasTy: The MOZART Study[NCT01947335]Phase 483 participants (Actual)Interventional2012-11-30Completed
IVUS Based Ultra-low Volume Contrast Media PCI to Reduce Contrast Induced Nephrology in Patient With Chronic Kidney disease-a Multi-center, Open Label, Randomized Trial (IVUS-CKD)[NCT05913362]320 participants (Anticipated)Interventional2023-10-01Not yet recruiting
Pre-existing Microalbuminuria Predicting Contrast-induced Acute Kidney Injury (CIAKI) Following Coronary Angiography (CAG)[NCT02808845]800 participants (Anticipated)Observational2016-12-31Not yet recruiting
Evaluation of Glomerular Filtration Rate Using Iohexol Plasma Clearance in Critically Ill Patients With Augmented Renal Creatinine Clearance[NCT04776486]90 participants (Anticipated)Interventional2020-09-03Recruiting
Predictive Value of CHA2DS2-VASC Score and Contrast Volume to Creatinine Clearance Ratio in Relation to Mehran Score for Contrast-Induced Nephropathy In ST- Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention[NCT03266458]210 participants (Anticipated)Observational [Patient Registry]2018-01-01Not yet recruiting
The Contrast Media and Nephrotoxicity Following Coronary Revascularization by Primary Angioplasty for Acute Myocardial Infarction. The CONTRAST-AMI Study.[NCT00827788]Phase 4432 participants (Anticipated)Interventional2008-12-31Completed
Department of Geriatrics[NCT02575092]Phase 2/Phase 34,000 participants (Actual)Interventional2015-11-01Completed
High Dose Atorvastatin Raises Threshold of Contrast Induced Nephropathy in Diabetic Patients Undergoing Elective Coronary Intervention[NCT04375787]Phase 4200 participants (Actual)Interventional2020-03-15Completed
Evaluation of the Effect of Dapagliflozin on Cardiac Remodeling in Post Myocardial Infarction Patients[NCT05335629]60 participants (Anticipated)Interventional2022-09-01Recruiting
N-Acetylcysteine to Prevent Radiocontrast Nephropathy in Emergency Department Patients[NCT00780962]Phase 2399 participants (Actual)Interventional2007-10-16Completed
PROVOCATION Trial - PROphylactic intraVenOus Hydration for Contrast Agent Toxicity PreventION[NCT00130598]Phase 2/Phase 3258 participants (Actual)Interventional2005-06-30Completed
Clinical Controlled Trial to Determinate the Role of Sodium Bicarbonate in the Prevention of Contrast-Induced Nephropathy in High-Risk Patients Undergoing to Diagnostic Coronariography and/or Percutaneous Coronary Intervention[NCT00424320]Phase 3100 participants Interventional2006-10-31Recruiting
BIcarbonato di Sodio e N-Acetilcisteina Nella Prevenzione Della Nefropatia da Mezzo di Contrasto Nell'infaRto mIocardico acutO(Registro BINARIO)[NCT01218178]520 participants (Actual)Observational2008-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Incidence of Contrast-induced Nephropathy

Increase >= 0.5 mg/dl in basal serum creatinine (NCT01947335)
Timeframe: 7 days

Interventionpercentage of participants (Number)
Angiography-guided PCI19
IVUS-guided PCI7.3

Total Volume of Iodine Contrast Used During Procedure

Total volume of iodine contrast administered during the index procedure. (NCT01947335)
Timeframe: Day 1

Interventionml (Median)
Angiography-guided PCI64.5
IVUS-guided PCI20.0

Major Adverse Cardiac Events

Composite of death, myocardial infarction or repeat revascularization (NCT01947335)
Timeframe: 30 days and 6 months

,
Interventionparticipants (Number)
30 days6-months
Angiography-guided PCI22
IVUS-guided PCI25

Number of Participants With Contrast-induced Nephropathy

Contrast-induced nephropathy was defined as an increase in serum creatinine level of greater than or equal to 0.5 mg/dL or an increase of 25% above baseline. The primary outcome was measured by the change in serum creatinine level from the pre-radiocontrast baseline to the serum creatinine level measured 48 to 72 hours after radiocontrast administration. (NCT00780962)
Timeframe: 48-72 hours

InterventionParticipants (Count of Participants)
N-Acetycysteine Group14
0.9% Sodium-chloride Group12

Reviews

4 reviews available for iohexol and Acute Kidney Injury

ArticleYear
A systematic review of cost-effectiveness analyses across the acute kidney injury landscape.
    Expert review of pharmacoeconomics & outcomes research, 2021, Volume: 21, Issue:4

    Topics: Acute Kidney Injury; Biomarkers; Contrast Media; Cost-Benefit Analysis; Humans; Iohexol; Renal Repla

2021
Nephrotoxicity of iso-osmolar iodixanol compared with nonionic low-osmolar contrast media: meta-analysis of randomized controlled trials.
    Radiology, 2009, Volume: 250, Issue:1

    Topics: Acute Kidney Injury; Aged; Cardiac Catheterization; Confidence Intervals; Contrast Media; Creatinine

2009
Cost-effectiveness of iso- versus low-osmolality contrast media in outpatients with high risk of contrast medium-induced nephropathy.
    Biomedica : revista del Instituto Nacional de Salud, 2012, Volume: 32, Issue:2

    Topics: Acute Kidney Injury; Aged; Colombia; Contrast Media; Cost-Benefit Analysis; Decision Trees; Drug Cos

2012
The role of osmolality in the incidence of contrast-induced nephropathy: a systematic review of angiographic contrast media in high risk patients.
    Kidney international, 2005, Volume: 68, Issue:5

    Topics: Acute Kidney Injury; Contrast Media; Humans; Incidence; Iohexol; Kidney Failure, Chronic; Osmolar Co

2005

Trials

26 trials available for iohexol and Acute Kidney Injury

ArticleYear
Rosiglitazone Alleviates Contrast-Induced Acute Kidney Injury in Rats via the PPAR
    Disease markers, 2022, Volume: 2022

    Topics: Acute Kidney Injury; Animals; Caspase 3; Creatinine; Furosemide; Interleukin-10; Iohexol; Kidney; Ni

2022
Impact of catalytic iron on mortality in patients with acute coronary syndrome exposed to iodinated radiocontrast-The Iscom Study.
    American heart journal, 2013, Volume: 165, Issue:5

    Topics: Acute Coronary Syndrome; Acute Kidney Injury; Contrast Media; Creatinine; Female; Follow-Up Studies;

2013
Refining the assessment of contrast-induced acute kidney injury: the load-to-damage relationship.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2014, Volume: 15, Issue:7

    Topics: Acute Kidney Injury; Aged; Contrast Media; Coronary Angiography; Creatinine; Dose-Response Relations

2014
Alprostadil plays a protective role in contrast-induced nephropathy in the elderly.
    International urology and nephrology, 2013, Volume: 45, Issue:4

    Topics: Acute Kidney Injury; Age Factors; Aged; Aged, 80 and over; Alprostadil; Blood Urea Nitrogen; Contras

2013
Prevention of contrast-induced nephropathy with prostaglandin E1 in high-risk patients undergoing percutaneous coronary intervention.
    International urology and nephrology, 2014, Volume: 46, Issue:4

    Topics: Acute Kidney Injury; Aged; Alprostadil; Contrast Media; Creatinine; Female; Glomerular Filtration Ra

2014
Acute kidney injury after using contrast during cardiac catheterization in children with heart disease.
    Journal of Korean medical science, 2014, Volume: 29, Issue:8

    Topics: Acute Kidney Injury; Biomarkers; Cardiac Catheterization; Child; Contrast Media; Fatty Acid-Binding

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Prevention of contrast-induced nephropathy with single bolus erythropoietin in patients with diabetic kidney disease: A randomized controlled trial.
    Nephrology (Carlton, Vic.), 2016, Volume: 21, Issue:4

    Topics: Acetylcysteine; Acute Kidney Injury; Aged; Aged, 80 and over; Biomarkers; Contrast Media; Coronary A

2016
A prospective, double-blind, randomized, controlled trial on the efficacy and cardiorenal safety of iodixanol vs. iopromide in patients with chronic kidney disease undergoing coronary angiography with or without percutaneous coronary intervention.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, Dec-01, Volume: 72, Issue:7

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Contrast Media;

2008
Comparison of iodixanol and iohexol in patients undergoing intravenous pyelography: a prospective controlled study.
    Renal failure, 2009, Volume: 31, Issue:3

    Topics: Acute Kidney Injury; Adult; Aged; Contrast Media; Creatinine; Cytokines; Double-Blind Method; Drug E

2009
Sodium bicarbonate plus isotonic saline versus saline for prevention of contrast-induced nephropathy in patients undergoing coronary angiography: a randomized controlled trial.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 54, Issue:4

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Creatinine; Double-Blin

2009
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
High incidence of nephropathy in neurosurgical patients after intra-arterial administration of low-osmolar and iso-osmolar contrast media.
    Acta radiologica (Stockholm, Sweden : 1987), 2011, May-01, Volume: 52, Issue:4

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Contrast Media; Diabetes Complications; Double-

2011
Impact of iso-osmolar versus low-osmolar contrast agents on contrast-induced nephropathy and tissue reperfusion in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (from the Contrast
    The American journal of cardiology, 2012, Jan-01, Volume: 109, Issue:1

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Cor

2012
Impact of iso-osmolar versus low-osmolar contrast agents on contrast-induced nephropathy and tissue reperfusion in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (from the Contrast
    The American journal of cardiology, 2012, Jan-01, Volume: 109, Issue:1

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Cor

2012
Impact of iso-osmolar versus low-osmolar contrast agents on contrast-induced nephropathy and tissue reperfusion in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (from the Contrast
    The American journal of cardiology, 2012, Jan-01, Volume: 109, Issue:1

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Cor

2012
Impact of iso-osmolar versus low-osmolar contrast agents on contrast-induced nephropathy and tissue reperfusion in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (from the Contrast
    The American journal of cardiology, 2012, Jan-01, Volume: 109, Issue:1

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Cor

2012
Efficacy of vitamin E and N-acetylcysteine in the prevention of contrast induced kidney injury in patients with chronic kidney disease: a double blind, randomized controlled trial.
    Wiener klinische Wochenschrift, 2012, Volume: 124, Issue:9-10

    Topics: Acetylcysteine; Acute Kidney Injury; Aged; Contrast Media; Double-Blind Method; Female; Free Radical

2012
Prophylaxis of contrast-induced nephropathy in patients undergoing coronary angiography.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2003, Volume: 60, Issue:4

    Topics: Acetylcysteine; Acute Kidney Injury; Aged; Chi-Square Distribution; Contrast Media; Coronary Angiogr

2003
Prevention of contrast-induced nephropathy in vascular patients undergoing angiography: a randomized controlled trial of intravenous N-acetylcysteine.
    Journal of vascular surgery, 2004, Volume: 40, Issue:6

    Topics: Acetylcysteine; Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Angiography; Antioxidants; Cont

2004
Cost-effectiveness of iodixanol in patients at high risk of contrast-induced nephropathy.
    American heart journal, 2005, Volume: 149, Issue:2

    Topics: Acute Kidney Injury; Angiography; Contrast Media; Coronary Angiography; Cost-Benefit Analysis; Healt

2005
Incidence of contrast nephropathy in patients receiving comprehensive intravenous and oral hydration.
    Swiss medical weekly, 2005, May-14, Volume: 135, Issue:19-20

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Female; Fluid Therapy; Gl

2005
Incidence of contrast nephropathy in patients receiving comprehensive intravenous and oral hydration.
    Swiss medical weekly, 2005, May-14, Volume: 135, Issue:19-20

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Female; Fluid Therapy; Gl

2005
Incidence of contrast nephropathy in patients receiving comprehensive intravenous and oral hydration.
    Swiss medical weekly, 2005, May-14, Volume: 135, Issue:19-20

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Female; Fluid Therapy; Gl

2005
Incidence of contrast nephropathy in patients receiving comprehensive intravenous and oral hydration.
    Swiss medical weekly, 2005, May-14, Volume: 135, Issue:19-20

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Female; Fluid Therapy; Gl

2005
I.v. N-acetylcysteine and emergency CT: use of serum creatinine and cystatin C as markers of radiocontrast nephrotoxicity.
    AJR. American journal of roentgenology, 2007, Volume: 189, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Adult; Biomarkers; Contrast Media; Creatinine; Cystatin C; Cyst

2007
Renal protection for coronary angiography in advanced renal failure patients by prophylactic hemodialysis. A randomized controlled trial.
    Journal of the American College of Cardiology, 2007, Sep-11, Volume: 50, Issue:11

    Topics: Acute Kidney Injury; Aged; Contrast Media; Coronary Angiography; Creatinine; Female; Humans; Iohexol

2007
Nephrotoxicity of ionic and nonionic contrast media in 1196 patients: a randomized trial. The Iohexol Cooperative Study.
    Kidney international, 1995, Volume: 47, Issue:1

    Topics: Acute Kidney Injury; Aged; Angiocardiography; Diabetes Complications; Diatrizoate Meglumine; Double-

1995
Adenosine antagonist theophylline prevents the reduction of glomerular filtration rate after contrast media application.
    Kidney international, 1994, Volume: 45, Issue:5

    Topics: Acute Kidney Injury; Adenosine; Aldosterone; Contrast Media; Creatinine; Double-Blind Method; Female

1994
Dose effect of nitrendipine on urinary enzymes and microproteins following non-ionic radiocontrast administration.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:3

    Topics: Acetylglucosaminidase; Acute Kidney Injury; Aged; Albuminuria; Alpha-Globulins; Angiography, Digital

1996
Enzyme markers of contrast media-induced renal failure.
    Investigative radiology, 1990, Volume: 25 Suppl 1

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Diatrizoate; Enzymes; Humans; Iohexol; Kidney

1990
A comparative study of the nephrotoxicity of iohexol, iopamidol and ioxaglate in peripheral angiography.
    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 1990, Volume: 41, Issue:3

    Topics: Acute Kidney Injury; Aged; Angiography; Creatinine; Diabetes Mellitus; Double-Blind Method; Female;

1990

Other Studies

116 other studies available for iohexol and Acute Kidney Injury

ArticleYear
Metabolomic Study on Iohexol-Induced Nephrotoxicity in Rats Based on NMR and LC-MS Analyses.
    Chemical research in toxicology, 2022, 02-21, Volume: 35, Issue:2

    Topics: Acute Kidney Injury; Animals; Chromatography, Liquid; Contrast Media; Injections, Subcutaneous; Iohe

2022
A convenient online desalination tube coupled with mass spectrometry for the direct detection of iodinated contrast media in untreated human spent hemodialysates.
    PloS one, 2022, Volume: 17, Issue:6

    Topics: Acute Kidney Injury; Contrast Media; Hemodialysis Solutions; Humans; Iodine Compounds; Iohexol; Mass

2022
Glomerular filtration rate in critically ill neonates and children: creatinine-based estimations versus iohexol-based measurements.
    Pediatric nephrology (Berlin, Germany), 2023, Volume: 38, Issue:4

    Topics: Acute Kidney Injury; Child; Creatinine; Critical Illness; Glomerular Filtration Rate; Humans; Infant

2023
A novel contrast-induced acute kidney injury mouse model based on low-osmolar contrast medium.
    Renal failure, 2022, Volume: 44, Issue:1

    Topics: Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Furosemide; Iohexol; Kidney; M

2022
Kidney outcomes in early adolescence following perinatal asphyxia and hypothermia-treated hypoxic-ischaemic encephalopathy.
    Pediatric nephrology (Berlin, Germany), 2023, Volume: 38, Issue:4

    Topics: Acute Kidney Injury; Adolescent; Asphyxia; Asphyxia Neonatorum; Creatinine; Cysts; Female; Humans; H

2023
Exploring the effects of edaravone in rats with contrast-induced acute kidney injury.
    Life sciences, 2022, Nov-15, Volume: 309

    Topics: Acute Kidney Injury; Animals; Antioxidants; Biomarkers; Contrast Media; Creatinine; Edaravone; Gluta

2022
Baicalin Alleviates Contrast-Induced Acute Kidney Injury Through ROS/NLRP3/Caspase-1/GSDMD Pathway-Mediated Proptosis in vitro.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Acute Kidney Injury; Caspase 1; Contrast Media; Cytokines; Exophthalmos; Flavonoids; Humans; Inflamm

2022
An in vivo and in vitro model on the protective effect of cilnidipine on contrast-induced nephropathy via regulation of apoptosis and CaMKⅡ/mPTP pathway.
    Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:1

    Topics: Acute Kidney Injury; Apoptosis; Atractyloside; Calcium-Calmodulin-Dependent Protein Kinase Type 2; C

2023
Ox-LDL aggravates contrast-induced injury of renal tubular epithelial cells.
    Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:8

    Topics: Acute Kidney Injury; Apoptosis; Epithelial Cells; Humans; Hypercholesterolemia; Iohexol; Lipoprotein

2023
Iohexol-Measured Glomerular Filtration Rate and Urinary Biomarker Changes between Vancomycin and Vancomycin Plus Piperacillin-Tazobactam in a Translational Rat Model.
    Antimicrobial agents and chemotherapy, 2023, 08-17, Volume: 67, Issue:8

    Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Biomarkers; Drug Therapy, Combination; Glomerul

2023
Incomplete Recovery from the Radiocontrast-Induced Dysregulated Cell Cycle, Adhesion, and Fibrogenesis in Renal Tubular Cells after Radiocontrast (Iohexol) Removal.
    International journal of molecular sciences, 2023, Jun-30, Volume: 24, Issue:13

    Topics: Acute Kidney Injury; Apoptosis; Cell Cycle; Contrast Media; Fibrosis; Humans; Iohexol

2023
Arginase2 mediates contrast-induced acute kidney injury via facilitating nitrosative stress in tubular cells.
    Redox biology, 2023, Volume: 67

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cisplatin; Humans; Iohexol; Kidney; Mice; Mice, Inbred C57B

2023
Investigating the Possible Protective Role of Direct Intra-arterial Administration of Mannitol and N-Acetylcysteine and Per Os Administration of Simvastatin Against Contrast-Induced Nephropathy: An Experimental Study in a Rabbit Model.
    Cardiovascular and interventional radiology, 2019, Volume: 42, Issue:12

    Topics: Acetylcysteine; Acute Kidney Injury; Administration, Oral; Animals; Contrast Media; Disease Models,

2019
Inhibition of xanthine oxidoreductase protects against contrast-induced renal tubular injury by activating adenosine monophosphate-activated protein kinase.
    Free radical biology & medicine, 2019, Volume: 145

    Topics: Acute Kidney Injury; AMP-Activated Protein Kinase Kinases; Animals; Antioxidants; Apoptosis; Contras

2019
Contrast-Associated Acute Kidney Injury in Endovascular Thrombectomy Patients With and Without Baseline Renal Impairment.
    Stroke, 2019, Volume: 50, Issue:12

    Topics: Acute Kidney Injury; Aged; Case-Control Studies; Contrast Media; Creatinine; Endovascular Procedures

2019
A novel rat model of contrast-induced nephropathy based on dehydration.
    Journal of pharmacological sciences, 2019, Volume: 141, Issue:1

    Topics: Acute Kidney Injury; Animals; Biomarkers; Contrast Media; Creatinine; Dehydration; Disease Models, A

2019
DDAH-2 alleviates contrast medium iopromide-induced acute kidney injury through nitric oxide synthase.
    Clinical science (London, England : 1979), 2019, 12-12, Volume: 133, Issue:23

    Topics: Acute Kidney Injury; Amidohydrolases; Animals; Arginine; Cell Line; Contrast Media; Female; Humans;

2019
Acetylbritannilactone attenuates contrast-induced acute kidney injury through its anti-pyroptosis effects.
    Bioscience reports, 2020, 02-28, Volume: 40, Issue:2

    Topics: Acute Kidney Injury; Animals; Apoptosis Regulatory Proteins; Cell Line; Disease Models, Animal; Epit

2020
MG53 protects against contrast-induced acute kidney injury by reducing cell membrane damage and apoptosis.
    Acta pharmacologica Sinica, 2020, Volume: 41, Issue:11

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Membrane; Epithelial Cells; Female; Humans; Iohexol; K

2020
Application of diffusion tensor imaging and blood oxygenation level-dependent magnetic resonance imaging to assess bilateral renal function induced by Iohexol in rabbits.
    BMC nephrology, 2020, 06-03, Volume: 21, Issue:1

    Topics: Acute Kidney Injury; Animals; Anisotropy; Blood Urea Nitrogen; Contrast Media; Creatinine; Cystatin

2020
MicroRNA-30c attenuates contrast-induced acute kidney injury by suppressing NLRP3 inflammasome.
    International immunopharmacology, 2020, Volume: 87

    Topics: Acute Kidney Injury; Animals; Cells, Cultured; Contrast Media; Epithelial Cells; Inflammasomes; Iohe

2020
Ferrotoxicity and Its Amelioration by Calcitriol in Cultured Renal Cells.
    Analytical cellular pathology (Amsterdam), 2021, Volume: 2021

    Topics: Acute Kidney Injury; Animals; Antioxidants; Calcitriol; Chlorocebus aethiops; Iohexol; Kidney; Lipid

2021
Kinetic Glomerular Filtration Rate Equations in Patients With Shock: Comparison With the Iohexol-Based Gold-Standard Method.
    Critical care medicine, 2021, 08-01, Volume: 49, Issue:8

    Topics: Acute Kidney Injury; Aged; Creatinine; Glomerular Filtration Rate; Humans; Intensive Care Units; Ioh

2021
Involvement of necroptosis in contrast-induced nephropathy in a rat CKD model.
    Clinical and experimental nephrology, 2021, Volume: 25, Issue:7

    Topics: Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Iohexol; Kidney Tubules, Proxi

2021
Novel biomarkers for post-contrast acute kidney injury identified from long non-coding RNA expression profiles.
    International journal of biological sciences, 2021, Volume: 17, Issue:3

    Topics: Acute Kidney Injury; Aged; Animals; Biomarkers; Contrast Media; Disease Models, Animal; Female; Gene

2021
A nephroprotective iodinated contrast agent with cardioprotective properties: A pilot study.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2021, Volume: 31, Issue:4

    Topics: Acute Kidney Injury; Animals; Contrast Media; Humans; Iohexol; Kidney; Male; Pilot Projects; Rats

2021
Ascorbic acid ameliorates renal injury in a murine model of contrast-induced nephropathy.
    BMC nephrology, 2017, 03-24, Volume: 18, Issue:1

    Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Caspase 3; Contrast Media; Cre

2017
Application of noninvasive functional imaging to monitor the progressive changes in kidney diffusion and perfusion in contrast-induced acute kidney injury rats at 3.0 T.
    Abdominal radiology (New York), 2018, Volume: 43, Issue:3

    Topics: Acute Kidney Injury; Animals; Contrast Media; Diffusion Magnetic Resonance Imaging; Disease Progress

2018
Serum Neutrophil Gelatinase-Associated Lipocalin and Urinary Kidney Injury Molecule-1 as Potential Biomarkers of Subclinical Nephrotoxicity After Gadolinium-Based and Iodinated-Based Contrast Media Exposure in Pediatric Patients with Normal Kidney Functio
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Sep-06, Volume: 23

    Topics: Acute Kidney Injury; Adolescent; Biomarkers; Case-Control Studies; Child; Child, Preschool; Contrast

2017
Predictors and Outcomes of Postcontrast Acute Kidney Injury after Endovascular Renal Artery Intervention.
    Journal of vascular and interventional radiology : JVIR, 2017, Volume: 28, Issue:12

    Topics: Acute Kidney Injury; Aged; Computed Tomography Angiography; Contrast Media; Female; Follow-Up Studie

2017
Effect of Atrial Fibrillation on Contrast-Induced Nephropathy Development in Patients With Non-ST-Segment Elevation Myocardial Infarction.
    Angiology, 2017, Volume: 68, Issue:10

    Topics: Acute Kidney Injury; Aged; Atrial Fibrillation; Contrast Media; Echocardiography; Female; Glomerular

2017
Platelet-to-lymphocyte ratio predicts contrast-induced acute kidney injury in diabetic patients with ST-elevation myocardial infarction.
    Biomarkers in medicine, 2017, Volume: 11, Issue:10

    Topics: Acute Kidney Injury; Aged; Area Under Curve; Blood Platelets; Contrast Media; Coronary Angiography;

2017
Continuous Infusion of Low-Dose Iohexol Measures Changing Glomerular Filtration Rate in Critically Ill Patients.
    Critical care medicine, 2018, Volume: 46, Issue:3

    Topics: Acute Kidney Injury; Adult; Contrast Media; Glomerular Filtration Rate; Humans; Infusions, Intraveno

2018
Oxidative stress caused by activation of NADPH oxidase 4 promotes contrast-induced acute kidney injury.
    PloS one, 2018, Volume: 13, Issue:1

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Line; Contrast Media; Enzyme Activation; Gene Silencin

2018
Astaxanthin attenuates contrast agent-induced acute kidney injury in vitro and in vivo via the regulation of SIRT1/FOXO3a expression.
    International urology and nephrology, 2018, Volume: 50, Issue:6

    Topics: Acute Kidney Injury; Animals; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrogen; Caspase 3;

2018
Mitophagy Plays a Protective Role in Iodinated Contrast-Induced Acute Renal Tubular Epithelial Cells Injury.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 46, Issue:3

    Topics: Acute Kidney Injury; Adenine; Apoptosis; Autophagy; Cell Line; Contrast Media; Epithelial Cells; Hum

2018
Comparison of iohexol and iodixanol induced nephrotoxicity, mitochondrial damage and mitophagy in a new contrast-induced acute kidney injury rat model.
    Archives of toxicology, 2018, Volume: 92, Issue:7

    Topics: Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Iohexol; Kidney Function Tests

2018
Bilateral Sustained Nephrograms After Parenteral Administration of Iodinated Contrast Material: A Potential Biomarker for Acute Kidney Injury, Dialysis, and Mortality.
    Mayo Clinic proceedings, 2018, Volume: 93, Issue:7

    Topics: Acute Kidney Injury; Administration, Intravenous; Aged; Biomarkers; Cardiac Catheterization; Contras

2018
Postcontrast Acute Kidney Injury in Pediatric Patients: A Cohort Study.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2018, Volume: 72, Issue:6

    Topics: Acute Kidney Injury; Adolescent; Child; Cohort Studies; Contrast Media; Female; Follow-Up Studies; H

2018
Shadow over abdomen.
    BMJ case reports, 2018, Aug-10, Volume: 2018

    Topics: Abdominal Cavity; Acute Kidney Injury; Catheterization, Central Venous; Computed Tomography Angiogra

2018
Involvement of organic cation transporter 2 in the metformin-associated increased lactate levels caused by contrast-induced nephropathy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 106

    Topics: Acidosis, Lactic; Acute Kidney Injury; Animals; Cell Line; Contrast Media; Disease Models, Animal; H

2018
Incidence of contrast-induced acute kidney injury in a large cohort of all-comers undergoing percutaneous coronary intervention: Comparison of five contrast media.
    International journal of cardiology, 2018, Dec-15, Volume: 273

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Cohort Studies; Contrast Media; Female; Humans; Incide

2018
Caspase-11-mediated tubular epithelial pyroptosis underlies contrast-induced acute kidney injury.
    Cell death & disease, 2018, 09-24, Volume: 9, Issue:10

    Topics: Acute Kidney Injury; Animals; Caspases; Caspases, Initiator; Cells, Cultured; Contrast Media; Diseas

2018
Rate of major adverse renal or cardiac events with iohexol compared to other low osmolar contrast media during interventional cardiovascular procedures.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2019, 02-01, Volume: 93, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Cardiac Catheterization; Cerebrovas

2019
Negligible Risk of Acute Renal Failure Among Hospitalized Patients After Contrast-Enhanced Imaging With Iodinated Versus Gadolinium-Based Agents.
    Investigative radiology, 2019, Volume: 54, Issue:5

    Topics: Acute Kidney Injury; Contrast Media; Female; Gadolinium; Humans; Inpatients; Iodine; Iohexol; Israel

2019
Creatinine versus cystatin C based glomerular filtration rate in critically ill patients.
    Journal of critical care, 2019, Volume: 52

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Creatinine; Critical Care; Critical Illness;

2019
Renal Safety of Intra-Arterial Treatment after Acute Ischemic Stroke with Multimodal CT Imaging selection.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019, Volume: 28, Issue:7

    Topics: Acute Kidney Injury; Aged; Biomarkers; Brain Ischemia; Clinical Decision-Making; Contrast Media; Cre

2019
Predicting the development of acute kidney injury in liver cirrhosis--an analysis of glomerular filtration rate, proteinuria and kidney injury biomarkers.
    Alimentary pharmacology & therapeutics, 2013, Volume: 37, Issue:10

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Adult; Aged; Biomarkers; Cohort Studies; Contrast Media;

2013
Anemia and the risk of contrast-induced nephropathy in patients with renal insufficiency undergoing contrast-enhanced MDCT.
    European journal of radiology, 2013, Volume: 82, Issue:10

    Topics: Acute Kidney Injury; Aged; Anemia; Causality; Comorbidity; Contrast Media; Drug-Related Side Effects

2013
Exposure to low- vs iso-osmolar contrast agents reduces NADPH-dependent reactive oxygen species generation in a cellular model of renal injury.
    Free radical biology & medicine, 2014, Volume: 68

    Topics: Acute Kidney Injury; Apoptosis; Contrast Media; Humans; Iohexol; Iopamidol; Kidney; NADP; NADPH Oxid

2014
Comparison of effects of isotonic sodium chloride with diltiazem in prevention of contrast-induced nephropathy.
    Renal failure, 2014, Volume: 36, Issue:3

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Blood Urea Nitrogen; Calcium Channel Blockers;

2014
A novel rat model of contrast-induced acute kidney injury.
    International journal of cardiology, 2014, Mar-01, Volume: 172, Issue:1

    Topics: Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Iohexol; Male; Rats, Sprague-D

2014
Atorvastatin ameliorates contrast medium-induced renal tubular cell apoptosis in diabetic rats via suppression of Rho-kinase pathway.
    European journal of pharmacology, 2014, Jan-15, Volume: 723

    Topics: Acute Kidney Injury; Animals; Apoptosis; Atorvastatin; bcl-2-Associated X Protein; Caspase 3; Contra

2014
Evaluation of intrarenal oxygenation in iodinated contrast-induced acute kidney injury-susceptible rats by blood oxygen level-dependent magnetic resonance imaging.
    Investigative radiology, 2014, Volume: 49, Issue:6

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Contrast Media; Feasibility Studies;

2014
Efficacy of preventive interventions for iodinated contrast-induced acute kidney injury evaluated by intrarenal oxygenation as an early marker.
    Investigative radiology, 2014, Volume: 49, Issue:10

    Topics: Acetylcysteine; Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Contrast Media; Dise

2014
Significant perturbation in renal functional magnetic resonance imaging parameters and contrast retention for iodixanol compared with iopromide: an experimental study using blood-oxygen-level-dependent/diffusion-weighted magnetic resonance imaging and com
    Investigative radiology, 2014, Volume: 49, Issue:11

    Topics: Acute Kidney Injury; Analysis of Variance; Animals; Contrast Media; Diffusion Magnetic Resonance Ima

2014
Extended renal outcomes with use of iodixanol versus iohexol after coronary angiography.
    BioMed research international, 2014, Volume: 2014

    Topics: Acute Kidney Injury; Age Distribution; Aged; Cohort Studies; Contrast Media; Coronary Angiography; F

2014
Intravenous contrast material exposure is not an independent risk factor for dialysis or mortality.
    Radiology, 2014, Volume: 273, Issue:3

    Topics: Acute Kidney Injury; Aged; Contrast Media; Electronic Health Records; Female; Humans; Injections, In

2014
Limb ischemic preconditioning protects against contrast-induced acute kidney injury in rats via phosphorylation of GSK-3β.
    Free radical biology & medicine, 2015, Volume: 81

    Topics: Acute Kidney Injury; Androstadienes; Animals; Apoptosis; Chromones; Contrast Media; Disease Models,

2015
A novel contrast-induced acute kidney injury model based on the 5/6-nephrectomy rat and nephrotoxicological evaluation of iohexol and iodixanol in vivo.
    Oxidative medicine and cellular longevity, 2014, Volume: 2014

    Topics: Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Iohexol; Kidney; Male; Nephrec

2014
Iohexol clearance for determination of glomerular filtration rate in rats induced to acute renal failure.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Acute Kidney Injury; Animals; Biomarkers; Cisplatin; Creatinine; Glomerular Filtration Rate; Inulin;

2015
Contrast-induced nephropathy following chronic total occlusion percutaneous coronary intervention in patients with chronic kidney disease.
    European radiology, 2015, Volume: 25, Issue:8

    Topics: Acute Kidney Injury; Aged; Contrast Media; Coronary Occlusion; Female; Glomerular Filtration Rate; H

2015
Intravenous contrast material and acute kidney injury: a need for caution.
    Radiology, 2015, Volume: 275, Issue:3

    Topics: Acute Kidney Injury; Contrast Media; Female; Humans; Iohexol; Male; Renal Dialysis; Triiodobenzoic A

2015
Response.
    Radiology, 2015, Volume: 275, Issue:3

    Topics: Acute Kidney Injury; Contrast Media; Female; Humans; Iohexol; Male; Renal Dialysis; Triiodobenzoic A

2015
Radiocontrast-induced nephropathy is attenuated by autophagy through regulation of apoptosis and inflammation.
    Human & experimental toxicology, 2016, Volume: 35, Issue:7

    Topics: Acute Kidney Injury; Adenine; Animals; Apoptosis; Autophagy; Cell Culture Techniques; Cell Line; Cel

2016
No Association between Intravenous Contrast Material Exposure and Adverse Clinical Outcome: Are Prevention Protocols Effective?
    Radiology, 2015, Volume: 277, Issue:1

    Topics: Acute Kidney Injury; Contrast Media; Female; Humans; Iohexol; Male; Renal Dialysis; Triiodobenzoic A

2015
Response.
    Radiology, 2015, Volume: 277, Issue:1

    Topics: Acute Kidney Injury; Contrast Media; Female; Humans; Iohexol; Male; Renal Dialysis; Triiodobenzoic A

2015
The incidence and significance of acute kidney injury following emergent contrast administration in patients with STEMI and stroke.
    Internal and emergency medicine, 2016, Volume: 11, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Aged; Cohort Studies; Contrast Media; Creatinine;

2016
A Retrospective Review of Contrast Nephropathy in a General Population.
    WMJ : official publication of the State Medical Society of Wisconsin, 2015, Volume: 114, Issue:3

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Contrast Media; Creatinine; Female; Humans; Iohexol; I

2015
Microalbuminuria in patients with preserved renal function as a risk factor for contrast-Induced acute kidney injury following invasive coronary angiography.
    European journal of radiology, 2016, Volume: 85, Issue:6

    Topics: Acute Kidney Injury; Age Factors; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood

2016
Iohexol clearance in unstable critically ill patients: a tool to assess glomerular filtration rate.
    Clinical chemistry and laboratory medicine, 2016, Nov-01, Volume: 54, Issue:11

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Creatinine; Critical Illness; Female; Glomerular Filtr

2016
Preclinical Studies of a Kidney Safe Iodinated Contrast Agent.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2016, Volume: 26, Issue:5

    Topics: Acute Kidney Injury; Animals; Apoptosis; beta-Cyclodextrins; Cell Line; Contrast Media; Disease Mode

2016
Incidences of acute kidney injury, dialysis, and graft loss following intravenous administration of low-osmolality iodinated contrast in patients with kidney transplants.
    Abdominal radiology (New York), 2016, Volume: 41, Issue:11

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Contrast Media; Female; Glomerular

2016
Salvianolic Acid B Prevents Iodinated Contrast Media-Induced Acute Renal Injury in Rats via the PI3K/Akt/Nrf2 Pathway.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Benzofurans; Biomarkers; Cell Line, Tumor; Co

2016
Platelet-to-Lymphocyte Ratio Predicts Contrast-Induced Acute Kidney Injury in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.
    Angiology, 2017, Volume: 68, Issue:5

    Topics: Acute Kidney Injury; Biomarkers; Blood Platelets; Contrast Media; Creatinine; Female; Humans; Iohexo

2017
Circulating MicroRNA-188, -30a, and -30e as Early Biomarkers for Contrast-Induced Acute Kidney Injury.
    Journal of the American Heart Association, 2016, 08-15, Volume: 5, Issue:8

    Topics: Acute Kidney Injury; Animals; Biomarkers; Circulating MicroRNA; Contrast Media; Disease Models, Anim

2016
A retrospective evaluation of contrast-induced kidney injury in dogs (2006-2012).
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2016, Volume: 26, Issue:5

    Topics: Acute Kidney Injury; Animals; Contrast Media; Creatinine; Dog Diseases; Dogs; Female; Hospitals, Uni

2016
Gender Difference in the Risk of Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography or Percutaneous Coronary Intervention.
    Angiology, 2017, Volume: 68, Issue:6

    Topics: Acute Kidney Injury; Aged; Contrast Media; Coronary Angiography; Female; Humans; Incidence; Iohexol;

2017
Augmented O-GlcNAc signaling via glucosamine attenuates oxidative stress and apoptosis following contrast-induced acute kidney injury in rats.
    Free radical biology & medicine, 2017, Volume: 103

    Topics: Acetylglucosamine; Acute Kidney Injury; Animals; Apoptosis; Contrast Media; Drug Evaluation, Preclin

2017
Predictive Value of CHA2DS2-VASC Score for Contrast-Induced Nephropathy After Percutaneous Coronary Intervention for Acute Coronary Syndrome.
    The American journal of cardiology, 2017, 03-15, Volume: 119, Issue:6

    Topics: Acute Coronary Syndrome; Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography

2017
Efficacy of oral supplemental hydration for the prevention of contrast-induced nephropathy in rats.
    Japanese journal of radiology, 2017, Volume: 35, Issue:4

    Topics: Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Fluid Therapy; Indomethacin; I

2017
Contrast-induced acute kidney injury in renal transplant recipients after cardiac catheterization.
    Clinical nephrology, 2009, Volume: 71, Issue:6

    Topics: Acute Kidney Injury; Cardiac Catheterization; Contrast Media; Creatinine; Female; Humans; Incidence;

2009
Comment on meta-analyses of trials comparing contrast media.
    Radiology, 2009, Volume: 252, Issue:1

    Topics: Acute Kidney Injury; Aged; Cardiac Catheterization; Confidence Intervals; Contrast Media; Creatinine

2009
Contrast-induced nephropathy after a second contrast exposure.
    Renal failure, 2010, Volume: 32, Issue:7

    Topics: Acute Kidney Injury; Aged; Contrast Media; Female; Humans; Iohexol; Iopamidol; Male; Middle Aged; Pr

2010
Impact of contrast-induced acute kidney injury with transient or persistent renal dysfunction on long-term outcomes of patients with acute myocardial infarction undergoing percutaneous coronary intervention.
    Heart (British Cardiac Society), 2011, Volume: 97, Issue:21

    Topics: Acute Kidney Injury; Adult; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Disease Progressio

2011
Incidence and risk factors for radiocontrast-induced nephropathy in patients with hepatocellular carcinoma undergoing transcatheter arterial chemoembolization.
    Clinical and experimental nephrology, 2011, Volume: 15, Issue:5

    Topics: Acute Kidney Injury; Aged; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Contrast Media

2011
Within-hospital and 30-day outcomes in 107,994 patients undergoing invasive coronary angiography with different low-osmolar iodinated contrast media.
    The American journal of cardiology, 2012, Jun-01, Volume: 109, Issue:11

    Topics: Acute Kidney Injury; Aged; Contrast Media; Coronary Angiography; Databases, Factual; Female; Hospita

2012
The osmolality of nonionic, iodinated contrast agents as an important factor for renal safety.
    Investigative radiology, 2012, Volume: 47, Issue:9

    Topics: Acute Kidney Injury; Animals; Biomarkers; Contrast Media; Iohexol; Kidney; Male; Mannitol; Osmolar C

2012
Effect of renin-angiotensin-aldosterone system blockade therapy on incidence of contrast-induced nephropathy in patients with chronic kidney disease.
    Iranian journal of kidney diseases, 2012, Volume: 6, Issue:6

    Topics: Acute Kidney Injury; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme In

2012
Effect of low-osmolar contrast medium iopromide and iso-osmolar iodixanol on DNA fragmentation in renal tubular cell culture.
    Clinical and experimental nephrology, 2013, Volume: 17, Issue:6

    Topics: Acute Kidney Injury; Cell Line; Contrast Media; DNA Fragmentation; Humans; Iohexol; Kidney; Osmolar

2013
A randomized trial of prophylactic acetylcysteine and theophylline compared with placebo for the prevention of renal tubular vacuolization in rats after iohexol administration.
    Academic radiology, 2003, Volume: 10, Issue:5

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Contrast Media; Free Radical Scavengers; Iohexol; Kidn

2003
Short- and long-term renal outcomes of immediate prophylactic hemodialysis after cardiovascular catheterizations in patients with severe renal insufficiency.
    International journal of cardiology, 2005, Jun-08, Volume: 101, Issue:3

    Topics: Acute Kidney Injury; Aged; Angina, Unstable; Cardiac Catheterization; Contrast Media; Coronary Angio

2005
Nephrotoxicity of low-osmolality versus iso-osmolality contrast agents: impact of N-acetylcysteine.
    Kidney international, 2005, Volume: 68, Issue:5

    Topics: Acetylcysteine; Acute Kidney Injury; Aged; Contrast Media; Female; Fluid Therapy; Humans; Iohexol; K

2005
Comparison of renal damage by iodinated contrast or gadolinium in an acute renal failure rat model based on serum creatinine levels and apoptosis degree.
    Journal of Korean medical science, 2005, Volume: 20, Issue:5

    Topics: Acute Kidney Injury; Animals; Apoptosis; Contrast Media; Creatine; Female; Gadolinium DTPA; Iohexol;

2005
The cost-effectiveness analysis (CEA) is dependent on the quality of the NEPHRIC study.
    American heart journal, 2006, Volume: 151, Issue:1

    Topics: Acute Kidney Injury; Clinical Trials as Topic; Contrast Media; Cost-Benefit Analysis; Humans; Iohexo

2006
A1 adenosine receptor knockout mice are protected against acute radiocontrast nephropathy in vivo.
    American journal of physiology. Renal physiology, 2006, Volume: 290, Issue:6

    Topics: Acute Kidney Injury; Adenosine A1 Receptor Antagonists; Animals; Apoptosis; Cells, Cultured; Contras

2006
Contrast-induced nephropathy in urgent coronary interventions.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2006, Volume: 7, Issue:10

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Analysis of Variance; Angioplasty, Balloon, Coronary;

2006
[New aspects of contrast nephropathy in cardiology].
    Revista espanola de cardiologia, 2007, Volume: 60, Issue:10

    Topics: Acute Coronary Syndrome; Acute Kidney Injury; Biomarkers; Contrast Media; Creatinine; Fluid Therapy;

2007
[Contrast-induced nephropathy and acute renal failure following emergent cardiac catheterization: incidence, risk factors and prognosis].
    Revista espanola de cardiologia, 2007, Volume: 60, Issue:10

    Topics: Acute Coronary Syndrome; Acute Kidney Injury; Cardiac Catheterization; Cohort Studies; Contrast Medi

2007
Acute renal haemodynamic effects of radiocontrast media in patients undergoing left ventricular and coronary angiography.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:5

    Topics: Acute Kidney Injury; Aged; Blood Flow Velocity; Contrast Media; Coronary Angiography; Creatinine; Fe

2008
Influence of the timing of cardiac catheterization and the amount of contrast media on acute renal failure after cardiac surgery.
    The American journal of cardiology, 2008, Apr-15, Volume: 101, Issue:8

    Topics: Acute Kidney Injury; Age Factors; Aged; Cardiac Catheterization; Cardiac Surgical Procedures; Cardio

2008
[Recurrent immune thrombocytopenia: a rare complication after contrast medium injection].
    Deutsche medizinische Wochenschrift (1946), 1995, Sep-15, Volume: 120, Issue:37

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Anti-Inflammatory Agents; Contrast Media;

1995
Modulation of the renal effects of contrast media by endothelium-derived nitric oxide in the rat.
    Investigative radiology, 1993, Volume: 28, Issue:9

    Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Arginine; Creatinine; Iohexol; Ioxaglic Acid; K

1993
Effects of femoral arteriography and low osmolar contrast agents on renal function.
    Acta radiologica (Stockholm, Sweden : 1987), 1993, Volume: 34, Issue:1

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Angiography; Contrast Media; Diabetes Mellitus;

1993
Effects of contrast media on renal microcirculation and oxygen tension. An experimental study in the rat.
    Acta radiologica. Supplementum, 1997, Volume: 409

    Topics: Acute Kidney Injury; Animals; Contrast Media; Diuretics; Erythrocyte Aggregation; Iohexol; Kidney; M

1997
Injection of low and iso-osmolar contrast medium decreases oxygen tension in the renal medulla.
    Kidney international, 1998, Volume: 53, Issue:3

    Topics: Acute Kidney Injury; Animals; Contrast Media; Hypoxia; Injections, Intravenous; Iohexol; Ioxaglic Ac

1998
Nephrotoxicity of high- and low-osmolar contrast media. The protective role of amlodipine in a rat model.
    Acta radiologica (Stockholm, Sweden : 1987), 2000, Volume: 41, Issue:5

    Topics: Acute Kidney Injury; Amlodipine; Analysis of Variance; Animals; Blood Urea Nitrogen; Calcium; Calciu

2000
Contrast-medium-induced nephrotoxicity: are all answers in for acetylcysteine?
    European radiology, 2001, Volume: 11, Issue:12

    Topics: Acetylcysteine; Acute Kidney Injury; Combined Modality Therapy; Contrast Media; Double-Blind Method;

2001
The rabbit renal toxicity test: a sensitive in vivo test for the nephrotoxicity of contrast agents.
    Academic radiology, 2002, Volume: 9 Suppl 1

    Topics: Acute Kidney Injury; Animals; Contrast Media; Injections, Intravenous; Iohexol; Iopamidol; Kidney; L

2002
Contrast media and regional renal blood flow. A study of the effects of ionic and non-ionic monomeric and dimeric contrast media in the rat.
    Acta radiologica. Supplementum, 1992, Volume: 378 ( Pt 3)

    Topics: Acute Kidney Injury; Animals; Contrast Media; Dehydration; Erythrocyte Aggregation; Glomerular Filtr

1992
[Acute renal insufficiency after computer tomography with a low-osmolarity contrast agent].
    Lakartidningen, 1992, Mar-11, Volume: 89, Issue:11

    Topics: Acute Kidney Injury; Aged; Female; Humans; Iohexol; Risk Factors; Tomography, X-Ray Computed

1992
Contrast media-induced renal tubular vacuolization. A light and electron microscopic study on rat kidneys.
    Investigative radiology, 1991, Volume: 26, Issue:10

    Topics: Acute Kidney Injury; Animals; Contrast Media; Diatrizoate; Female; Gadolinium DTPA; Iohexol; Kidney

1991
Persistent CT nephrogram: significance in the diagnosis of contrast nephropathy--an update.
    Urologic radiology, 1991, Volume: 12, Issue:4

    Topics: Acute Kidney Injury; Aged; Contrast Media; Diatrizoate; Female; Humans; Iohexol; Kidney; Kidney Cort

1991
Nephrotoxicity of nonionic contrast media after cardiac angiography.
    The American journal of cardiology, 1989, Oct-01, Volume: 64, Issue:12

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Angiocardiography; Cardiac Catheterization; Dos

1989
Acute renal dysfunction in high-risk patients after angiography: comparison of ionic and nonionic contrast media.
    Radiology, 1989, Volume: 170, Issue:1 Pt 1

    Topics: Acute Kidney Injury; Adolescent; Aged; Aged, 80 and over; Angiography; Child; Contrast Media; Humans

1989
Acute renal failure following low osmolality radiocontrast dye.
    Clinical cardiology, 1988, Volume: 11, Issue:6

    Topics: Acute Kidney Injury; Cardiac Catheterization; Female; Heart Failure; Heart Valve Diseases; Humans; I

1988