iofetamine has been researched along with Subarachnoid Hemorrhage in 11 studies
Iofetamine: An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prediction of cerebral infarction due to vasospasm (VS) following aneurysmal subarachnoid haemorrhage (SAH) was investigated using acetazolamide-activated (A-A) N-isopropyl-p-[123I]iodoamphetamine (123I-IMP) single photon emission computed tomography (SPECT) in 79 SAH patients." | 7.68 | Prediction of cerebral infarction due to vasospasm following aneurysmal subarachnoid haemorrhage using acetazolamide-activated 123I-IMP SPECT. ( Funakoshi, T; Kimura, T; Shinoda, J, 1993) |
| "Prediction of cerebral infarction due to vasospasm (VS) following aneurysmal subarachnoid haemorrhage (SAH) was investigated using acetazolamide-activated (A-A) N-isopropyl-p-[123I]iodoamphetamine (123I-IMP) single photon emission computed tomography (SPECT) in 79 SAH patients." | 3.68 | Prediction of cerebral infarction due to vasospasm following aneurysmal subarachnoid haemorrhage using acetazolamide-activated 123I-IMP SPECT. ( Funakoshi, T; Kimura, T; Shinoda, J, 1993) |
| "Chronic hydrocephalus after aneurysmal sub-arachnoid haemorrhage (SAH) is easily diagnosed in most cases." | 2.69 | Role of 123I-IMP SPET in the early diagnosis of borderline chronic hydrocephalus after aneurysmal subarachnoid haemorrhage. ( Kondoh, I; Ohkuma, H; Suzuki, S; Tanaka, M, 2000) |
| "After recovery from symptomatic cerebral vasospasm, the patient became restless and suffered from right hemiparesis on post-SAH day 12." | 1.56 | Symptomatic Cerebral Hyperperfusion After Cerebral Vasospasm Associated with Aneurysmal Subarachnoid Hemorrhage. ( Endo, H; Fujimura, M; Niizuma, K; Sakata, H; Tominaga, T, 2020) |
| "Precise in vivo evaluation of cerebral vasospasm caused by subarachnoid hemorrhage has remained a critical but unsolved issue in experimental small animal models." | 1.38 | A novel intravital method to evaluate cerebral vasospasm in rat models of subarachnoid hemorrhage: a study with synchrotron radiation angiography. ( Bao, Y; Cai, J; Chen, L; Chen, Z; He, C; Ling, F; Lou, M; Sun, Y; Xia, W; Yang, GY; Yuan, F, 2012) |
| "In the subarachnoid hemorrhage patients, the vasospastic area showed significantly lower rCBF than the normal cortical rCBF (p < 0." | 1.30 | Regional cerebral blood flow measurement with iodine-123-IMP autoradiography: normal values, reproducibility and sensitivity to hypoperfusion. ( Hatazawa, J; Iida, H; Miura, Y; Murakami, M; Sato, T; Shimosegawa, E, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Sakata, H | 1 |
| Endo, H | 1 |
| Fujimura, M | 1 |
| Niizuma, K | 1 |
| Tominaga, T | 1 |
| Matano, F | 1 |
| Murai, Y | 1 |
| Adachi, K | 1 |
| Koketsu, K | 1 |
| Kitamura, T | 1 |
| Teramoto, A | 1 |
| Okubo, S | 1 |
| Katayama, Y | 1 |
| Sekine, T | 1 |
| Takagi, R | 1 |
| Kumita, S | 1 |
| Ohtonari, T | 1 |
| Kakinuma, K | 1 |
| Kito, T | 1 |
| Ezuka, I | 1 |
| Kanazawa, T | 1 |
| Cai, J | 1 |
| Sun, Y | 1 |
| Yuan, F | 1 |
| Chen, L | 1 |
| He, C | 1 |
| Bao, Y | 1 |
| Chen, Z | 1 |
| Lou, M | 1 |
| Xia, W | 1 |
| Yang, GY | 1 |
| Ling, F | 1 |
| Ohkuma, H | 2 |
| Suzuki, S | 2 |
| Kudo, K | 1 |
| Islam, S | 1 |
| Kikkawa, T | 1 |
| Matsuda, H | 1 |
| Seki, H | 1 |
| Ishida, H | 1 |
| Hisada, K | 1 |
| Kobayashi, H | 1 |
| Hayashi, M | 1 |
| Yamamoto, S | 1 |
| Kimura, T | 1 |
| Shinoda, J | 1 |
| Funakoshi, T | 1 |
| Hatazawa, J | 1 |
| Iida, H | 1 |
| Shimosegawa, E | 1 |
| Sato, T | 1 |
| Murakami, M | 1 |
| Miura, Y | 1 |
| Tanaka, M | 1 |
| Kondoh, I | 1 |
| Kamiya, K | 1 |
| Yamashita, N | 1 |
| Nagai, H | 1 |
| Mizawa, I | 1 |
| Taguchi, M | 1 |
| Nakajo, M | 1 |
| Shirono, K | 1 |
| Hori, A | 1 |
| Shinohara, S | 1 |
| Okada, A | 1 |
| Kiku, T | 1 |
| Haranomura, H | 1 |
| Sawada, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| C-arm Cone Beam CTA and CTP With Acetazolamide Challenge in Aneurysmal Subarachnoid Hemorrhage: Evaluating Predictability for Early Ischemia in Cerebral Vasospasm[NCT03377049] | Phase 4 | 11 participants (Actual) | Interventional | 2019-07-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Clinical neurological deterioration not attributable to other causes, mores specifically not due to re-bleeding, hydrocephalus, or metabolic changes. (NCT03377049)
Timeframe: Day 1-14 during the hospitalization
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetazolamide Challenge | 2 |
Using perfusion map values, relative percent change will be calculated (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour
| Intervention | percent change (Mean) |
|---|---|
| Acetazolamide Challenge | 19.785 |
Using perfusion map values, relative percent change will be calculated (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour
| Intervention | percent change (Mean) |
|---|---|
| Acetazolamide Challenge | 21.659 |
The data that will be statistically compared is the pre-diamox perfusion in comparison to the post-diamox perfusion. A statistically significant change increase in CBF represents an appropriate response to Diamox. Lack of change in CBF or decrease in CBF could be suggestive of potential for developing vasospasm. (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour
| Intervention | percent change (Mean) |
|---|---|
| Acetazolamide Challenge | 20.722 |
1 trial available for iofetamine and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Role of 123I-IMP SPET in the early diagnosis of borderline chronic hydrocephalus after aneurysmal subarachnoid haemorrhage.
Topics: Aged; Cerebral Ventricles; Cerebrovascular Circulation; Female; Humans; Hydrocephalus; Intracranial | 2000 |
10 other studies available for iofetamine and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Symptomatic Cerebral Hyperperfusion After Cerebral Vasospasm Associated with Aneurysmal Subarachnoid Hemorrhage.
Topics: Aged; Aneurysm, Ruptured; Antihypertensive Agents; Cerebral Angiography; Cerebrovascular Circulation | 2020 |
Reversible cerebral vasoconstriction syndrome associated with subarachnoid hemorrhage triggered by hydroxyzine pamoate.
Topics: Cerebral Angiography; Cerebrovascular Disorders; Drug Eruptions; Female; Histamine H1 Antagonists; H | 2013 |
Diffusion-perfusion mismatch in symptomatic vasospasm after subarachnoid hemorrhage.
Topics: Aged; Cerebral Arteries; Cerebrovascular Circulation; Diffusion Magnetic Resonance Imaging; Early Di | 2008 |
A novel intravital method to evaluate cerebral vasospasm in rat models of subarachnoid hemorrhage: a study with synchrotron radiation angiography.
Topics: Analysis of Variance; Angiography; Animals; Brain; Cerebral Arteries; Intracranial Pressure; Iodine | 2012 |
Cortical blood flow during cerebral vasospasm after aneurysmal subarachnoid hemorrhage: three-dimensional N-isopropyl-p-[(123)I]iodoamphetamine single photon emission CT findings.
Topics: Adult; Aged; Angiography, Digital Subtraction; Blood Flow Velocity; Blood Volume; Brain Ischemia; Ce | 2003 |
[Regional cerebral blood flow measurement by N-isopropyl-p-(123I) iodoamphetamine].
Topics: Amphetamines; Cerebrovascular Circulation; Female; Humans; Iodine Radioisotopes; Iofetamine; Middle | 1984 |
Prediction of cerebral infarction due to vasospasm following aneurysmal subarachnoid haemorrhage using acetazolamide-activated 123I-IMP SPECT.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Amphetamines; Aneurysm, Ruptured; Brain; Cerebral Inf | 1993 |
Regional cerebral blood flow measurement with iodine-123-IMP autoradiography: normal values, reproducibility and sensitivity to hypoperfusion.
Topics: Aged; Amphetamines; Autoradiography; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascul | 1997 |
Investigation of normal pressure hydrocephalus by 123I-IMP SPECT.
Topics: Aged; Amphetamines; Brain Diseases; Cerebrospinal Fluid Shunts; Cerebrovascular Circulation; Frontal | 1991 |
[Clinical experience of N-isopropyl-p-[123I] iodoamphetamine imaging in a case of brain death].
Topics: Amphetamines; Brain; Brain Death; Female; Humans; Iodine Radioisotopes; Iofetamine; Middle Aged; Rad | 1986 |