Page last updated: 2024-10-29

iofetamine and Parkinson Disease

iofetamine has been researched along with Parkinson Disease in 25 studies

Iofetamine: An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
"1 patient with progressive supranuclear palsy (PSP), 1 patient with multiple system atrophy (MSA), and 7 normal control subjects using single photon emission computed tomography (SPECT) with the IMP-ARG method."2.68[Analysis of Parkinson's disease and related syndromes using 123I-IMP-SPECT with the ARG method]. ( Kageyama, H; Kikuchi, S; Tashiro, K, 1997)
"However, there are few reports on Parkinson's disease(PD) regarding the impairment of GABA/BZR in the cerebral cortex."2.40[Evaluation of benzodiazepine receptor in the cerebral cortex of Parkinson's disease using 123I-iomazenil SPECT]. ( Kawabata, K; Tachibana, H, 1997)
"Fifty-two cases of Parkinson's disease and 10 control cases were studied."1.33N-isopropyl-p- 123I iodoamphetamine single photon emission computed tomography study of Parkinson's disease with dementia. ( Hara, N; Kameyama, M; Kubori, T; Matsui, H; Miyoshi, T; Nishinaka, K; Oda, M; Tamura, A; Udaka, F, 2005)
"Thirty nondemented patients with Parkinson's disease were studied."1.33Frontal assessment battery and brain perfusion image in Parkinson's disease. ( Hara, N; Kameyama, M; Kubori, T; Matsui, H; Miyoshi, T; Nishinaka, K; Oda, M; Tamura, A; Udaka, F, 2006)
"We examined patients with and without auditory hallucinations, using n-isopropyl-p-[123I]iodoamphetamine single photon emission computed tomographic imaging."1.33Hypoperfusion of the auditory and prefrontal cortices in Parkinsonian patients with verbal hallucinations. ( Hara, N; Komatsu, K; Kubori, T; Matsui, H; Nishinaka, K; Oda, M; Udaka, F, 2006)
"In nondemented patients with Parkinson's disease, perfusion defects were frequently found in the parietal cortex at a threshold value of 65%."1.29Three-dimensional surface display of brain perfusion with 123I-IMP in Parkinson's disease. ( Fukuchi, M; Kawabata, K; Sugita, M; Tachibana, H; Tomino, Y, 1994)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.00)18.7374
1990's9 (36.00)18.2507
2000's10 (40.00)29.6817
2010's4 (16.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ichinose, Y1
Ishiura, H1
Tanaka, M1
Yoshimura, J1
Doi, K1
Umeda, T1
Yamauchi, H1
Tsuchiya, M1
Koh, K1
Yamashiro, N1
Mitsui, J1
Goto, J1
Onishi, H1
Ohtsuka, T1
Shindo, K1
Morishita, S1
Tsuji, S1
Takiyama, Y1
Osada, O1
Iwasaki, A1
Imamura, K1
Okayasu, N1
Nagatsu, T1
Nagai, T1
Kajita, Y1
Maesawa, S1
Nakatsubo, D1
Yoshida, K2
Kato, K1
Wakabayashi, T1
Kamei, H1
Nakajima, T1
Fukuhara, N1
Kasama, S1
Tachibana, H5
Kawabata, K5
Yoshikawa, H1
Matsui, H5
Udaka, F5
Miyoshi, T4
Hara, N5
Tamaura, A1
Oda, M5
Kubori, T5
Nishinaka, K5
Kameyama, M3
Mito, Y1
Yabe, I1
Makino, K1
Hirotani, M1
Tashiro, K2
Kikuchi, S2
Sasaki, H1
Tamura, A2
Sakai, T1
Kuzuhara, S1
Komatsu, K2
Tomino, Y1
Sugita, M3
Fukuchi, M1
Odano, I2
Ohkubo, M1
Takahashi, N1
Ohtaki, H1
Noguchi, E1
Hatano, M1
Yamasaki, Y1
Yokoi, T1
Nishihara, M2
Kageyama, H1
Shibuya, N1
Okuda, B1
Takeda, M1
Mizuno, T1
Nishiyama, K1
Hitoshi, S1
Takeda, K1
Sakuta, M1
Yamamoto, K1
Umahara, T1
Kano, H1
Iwamoto, T1
Katsunuma, H1
Tachikawa, K1
Tachikawa, S1
Kuwabara, Y1
Ichiya, Y1
Otsuka, M1
Tahara, T1
Fukumura, T1
Gunasekera, R1
Masuda, K1
Hayashi, H1
Higuchi, S1
Sakai, K1
Ishikawa, A1
Nishizawa, S1
Tanada, S1
Yonekura, Y1
Fujita, T1
Mukai, T1
Saji, H1
Fukuyama, H1
Harada, K1
Ishikawa, M1

Reviews

1 review available for iofetamine and Parkinson Disease

ArticleYear
[Evaluation of benzodiazepine receptor in the cerebral cortex of Parkinson's disease using 123I-iomazenil SPECT].
    Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55, Issue:1

    Topics: Amphetamines; Animals; Cerebral Cortex; Flumazenil; Humans; Iodine Radioisotopes; Iofetamine; Parkin

1997

Trials

2 trials available for iofetamine and Parkinson Disease

ArticleYear
Cerebral blood flow in Parkinson's disease, dementia with Lewy bodies, and Alzheimer's disease according to three-dimensional stereotactic surface projection imaging.
    Dementia and geriatric cognitive disorders, 2005, Volume: 19, Issue:5-6

    Topics: Aged; Alzheimer Disease; Brain Diseases; Cerebrovascular Circulation; Cognition Disorders; Humans; I

2005
[Analysis of Parkinson's disease and related syndromes using 123I-IMP-SPECT with the ARG method].
    Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55, Issue:1

    Topics: Aged; Amphetamines; Brain; Diagnosis, Differential; Female; Humans; Iodine Radioisotopes; Iofetamine

1997

Other Studies

22 other studies available for iofetamine and Parkinson Disease

ArticleYear
Neuroimaging, genetic, and enzymatic study in a Japanese family with a GBA gross deletion.
    Parkinsonism & related disorders, 2019, Volume: 61

    Topics: Aged; Aged, 80 and over; Asian People; Brain; Exons; Family; Female; Gene Deletion; Glucosylceramida

2019
A case of successful treatment with donepezil of olfactory hallucination in parkinson disease.
    Rinsho shinkeigaku = Clinical neurology, 2017, 01-31, Volume: 57, Issue:1

    Topics: Aged; Cerebrovascular Circulation; Donepezil; Female; Hallucinations; Humans; Indans; Iodine Radiois

2017
Cerebral blood flow and freezing of gait in Parkinson's disease.
    Acta neurologica Scandinavica, 2012, Volume: 126, Issue:3

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Cerebrovascular Circulation; Disability Evaluation; D

2012
Preoperative regional cerebral blood flow and postoperative clinical improvement in patients with Parkinson's disease undergoing subthalamic nucleus deep brain stimulation.
    Neurologia medico-chirurgica, 2012, Volume: 52, Issue:12

    Topics: Aged; Autoradiography; Brain; Deep Brain Stimulation; Female; Humans; Image Interpretation, Computer

2012
[Statistic rCBF study of extrapyramidal disorders].
    No to shinkei = Brain and nerve, 2002, Volume: 54, Issue:8

    Topics: Aged; Basal Ganglia Diseases; Cerebrovascular Circulation; Diagnosis, Differential; Female; Humans;

2002
Three-dimensional stereotactic surface projection study of freezing of gait and brain perfusion image in Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:10

    Topics: Aged; Brain; Case-Control Studies; Cerebrovascular Circulation; Female; Gait; Humans; Image Interpre

2005
Brain 3D-SSP SPECT analysis in dementia with Lewy bodies, Parkinson's disease with and without dementia, and Alzheimer's disease.
    Clinical neurology and neurosurgery, 2005, Volume: 107, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cerebrovascular Circulation; Femal

2005
N-isopropyl-p- 123I iodoamphetamine single photon emission computed tomography study of Parkinson's disease with dementia.
    Internal medicine (Tokyo, Japan), 2005, Volume: 44, Issue:10

    Topics: Aged; Dementia; Female; Humans; Iofetamine; Male; Parkinson Disease; Radiopharmaceuticals; Tomograph

2005
Frontal assessment battery and brain perfusion image in Parkinson's disease.
    Journal of geriatric psychiatry and neurology, 2006, Volume: 19, Issue:1

    Topics: Aged; Blood Flow Velocity; Brain; Brain Ischemia; Cognition Disorders; Dominance, Cerebral; Female;

2006
[Correlation of the cognitive function and the duration of the illness with the regional cerebral blood flow in the patients with Parkinson's disease: objective evaluation using stereotactic extraction estimation analysis in 123I-IMP SPECT].
    No to shinkei = Brain and nerve, 2006, Volume: 58, Issue:1

    Topics: Aged; Cerebral Cortex; Cerebrovascular Circulation; Cognition; Female; Humans; Iofetamine; Male; Mid

2006
Wisconsin Card Sorting Test and brain perfusion imaging in Parkinson's disease.
    Parkinsonism & related disorders, 2006, Volume: 12, Issue:5

    Topics: Aged; Cerebrovascular Circulation; Data Interpretation, Statistical; Female; Humans; Image Processin

2006
Hypoperfusion of the auditory and prefrontal cortices in Parkinsonian patients with verbal hallucinations.
    Movement disorders : official journal of the Movement Disorder Society, 2006, Volume: 21, Issue:12

    Topics: Aged; Aged, 80 and over; Auditory Cortex; Female; Hallucinations; Humans; Imaging, Three-Dimensional

2006
Three-dimensional surface display of brain perfusion with 123I-IMP in Parkinson's disease.
    Neuroradiology, 1994, Volume: 36, Issue:4

    Topics: Aged; Aged, 80 and over; Amphetamines; Brain; Cerebellum; Cerebral Cortex; Computer Simulation; Deme

1994
[A new graphic method for evaluation of distribution volume on N-isopropyl-p-[123I]iodoamphetamine (IMP) SPECT].
    Kaku igaku. The Japanese journal of nuclear medicine, 1993, Volume: 30, Issue:10

    Topics: Aged; Amphetamines; Brain; Cerebrovascular Circulation; Diagnosis, Differential; Female; Humans; Iod

1993
[Memory function in patients with Parkinson's disease: in relation to neuropsychological tests and cerebral blood flow].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2001, Volume: 38, Issue:2

    Topics: Aged; Brain; Cerebrovascular Circulation; Female; Humans; Iofetamine; Male; Memory; Neuropsychologic

2001
[Three-dimensional surface display with 123I-IMP in corticobasal degeneration].
    Rinsho shinkeigaku = Clinical neurology, 1992, Volume: 32, Issue:7

    Topics: Aged; Amphetamines; Apraxias; Cerebral Cortex; Cerebrovascular Circulation; Female; Humans; Iodine R

1992
[The effect of anticholinergic drugs on 123I-IMP SPECT in Parkinson's disease].
    Rinsho shinkeigaku = Clinical neurology, 1992, Volume: 32, Issue:4

    Topics: Aged; Amphetamines; Brain; Female; Humans; Iodine Radioisotopes; Iofetamine; Male; Middle Aged; Para

1992
[Analysis of cognitive function and regional cerebral blood flow in Parkinson's disease by 123I-IMP SPECT].
    Rinsho shinkeigaku = Clinical neurology, 1992, Volume: 32, Issue:1

    Topics: Aged; Amphetamines; Cerebrovascular Circulation; Cognition; Female; Humans; Iodine Radioisotopes; Io

1992
[An MRI and SPECT study of frozen gait without other manifestations of parkinsonism in the elderly].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1991, Volume: 28, Issue:3

    Topics: Amphetamines; Brain; Dementia; Gait; Humans; Iodine Radioisotopes; Iofetamine; Magnetic Resonance Im

1991
Differential diagnosis of bilateral parietal abnormalities in I-123 IMP SPECT imaging.
    Clinical nuclear medicine, 1990, Volume: 15, Issue:12

    Topics: Aged; Alzheimer Disease; Amphetamines; Brain Diseases; Dementia, Multi-Infarct; Diagnosis, Different

1990
[Clinical evaluation of Parkinson's disease using 123I-IMP SPECT].
    Kaku igaku. The Japanese journal of nuclear medicine, 1989, Volume: 26, Issue:11

    Topics: Aged; Amphetamines; Atrophy; Brain; Cerebrovascular Circulation; Female; Humans; Iodine Radioisotope

1989
Regional dynamics of N-isopropyl-(123I)p-iodoamphetamine in human brain.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1989, Volume: 30, Issue:2

    Topics: Alzheimer Disease; Amphetamines; Brain; Brain Neoplasms; Cerebrovascular Circulation; Cerebrovascula

1989