Page last updated: 2024-10-29

iofetamine and Melanoma

iofetamine has been researched along with Melanoma in 32 studies

Iofetamine: An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
" A comparison group of five patients with melanoma with no clinical or radiologic evidence of brain involvement and 46 of 47 patients without malignant melanoma but with known brain tumors of other histologic types had normal or decreased iofetamine I 123 brain uptake in the region of the tumor."7.67Increased iofetamine I 123 brain uptake in metastatic melanoma. ( English, RJ; Holman, BL; Ichise, M; Johnson, KA; Kaplan, WD; Mueller, SP; Nagel, JS; Schober, O, 1988)
" A comparison group of five patients with melanoma with no clinical or radiologic evidence of brain involvement and 46 of 47 patients without malignant melanoma but with known brain tumors of other histologic types had normal or decreased iofetamine I 123 brain uptake in the region of the tumor."3.67Increased iofetamine I 123 brain uptake in metastatic melanoma. ( English, RJ; Holman, BL; Ichise, M; Johnson, KA; Kaplan, WD; Mueller, SP; Nagel, JS; Schober, O, 1988)
"Taking a biopsy of malignant melanoma is generally contraindicated because of the high risk of inducing metastasis."1.32Rectal malignant melanoma diagnosed by N-isopropyl- p-123I-iodoamphetamine single photon emission computed tomography and 5-S-cysteinyl dopa: report of a case. ( Abe, K; Aoki, T; Hayashi, M; Kitamura, K; Koyanagi, Y; Mori, M; Saito, H; Sato, S; Tsuchida, A; Umezu, K; Yamagishi, T, 2003)
"Eye uptake has been a potential concern with N-isopropyl-p-[123I]iodoamphetamine (I-123 IMP) because it has been observed in certain animal species."1.27The relationship of the eye uptake of N-isopropyl-p-[123I]iodoamphetamine to melanin production. ( Hill, TC; Holman, BL; Kaplan, ML; Lee, RG; Lin, TH; Wick, MM; Wu, JL, 1984)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199011 (34.38)18.7374
1990's7 (21.88)18.2507
2000's10 (31.25)29.6817
2010's3 (9.38)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Yamazaki, K1
Nishii, R1
Maeda, T1
Makishima, H1
Kasuya, G1
Chang, T1
Tamura, K1
Wakatsuki, M1
Tsuji, H2
Murakami, K1
Higashi, T1
Inoue, R1
Saishin, Y1
Shima, C1
Yoshikawa, H3
Ohguro, N1
Tano, Y1
Ito, Y1
Doi, H1
Ishida-Yamamto, A1
Iizuka, H1
Yoshimura, M2
Kanesaka, N1
Saito, K2
Koizumi, K2
Tokuuye, K1
Goto, H4
Arima, M1
Kagimoto, T1
Kohno, RI1
Ishibashi, T1
Endo, M1
Kondo, S1
Iida, K1
Jimbow, K1
Sato, S1
Aoki, T1
Umezu, K1
Mori, M1
Hayashi, M1
Saito, H1
Kitamura, K1
Tsuchida, A1
Koyanagi, Y1
Yamagishi, T1
Abe, K3
Murata, K2
Suzuki, K1
Ayakawa, Y1
Higashi, N1
Paul Lin, PJ1
Kato, K2
Kubota, T1
Ikeda, M1
Tadokoro, M1
Abe, S1
Nakano, S2
Nishino, M1
Kobayashi, H1
Ishigaki, T1
Sasaki, M1
Koga, H1
Kaneko, K1
Sawamoto, H1
Honda, H1
Akata, S2
Shindo, H1
Park, J1
Hirose, H1
Holman, BL2
Wick, MM1
Kaplan, ML1
Hill, TC1
Lee, RG1
Wu, JL1
Lin, TH1
Miyazaki, T1
Ohnishi, T1
Hoshi, H1
Jinnouchi, S1
Futami, S1
Nagamachi, S1
Watanabe, K1
Hamasuna, R1
Ueda, T1
Wakisaka, S1
Watanabe, N1
Seto, H1
Yokoyama, K1
Matsuda, H1
Shimizu, M1
Tonami, N1
Hisada, K1
Kakishita, M1
Toya, K1
Fujii, H1
Tominaga, S1
Nakamura, K1
Kosuda, S1
Kubo, A1
Mashino, H1
Akatsuka, S1
Kotake, F1
Kawanishi, M1
Ishii, I2
Kakizaki, D1
Usui, M1
Takano, S1
Saito, M1
Ohbu, M1
Miyasaka, Y1
Yada, K1
Kan, S1
Takagi, H1
Dewey, SH1
Leonard, JC1
Nakabeppu, Y1
Nakajo, M1
Iwashita, S1
Tanoue, T1
Shinohara, S1
Ishibashi, M1
Morita, S1
Sasai, Y1
Ohtake, H1
Nagel, JS1
Ichise, M1
Mueller, SP1
Johnson, KA1
English, RJ1
Kaplan, WD1
Schober, O1
Morita, K3
Ono, S4
Fukunaga, M4
Otsuka, N4
Nagai, K4
Yanagimoto, S4
Tomomitsu, T4
Morita, R2
Furukawa, T3
Kubo, K1
Itoh, K1
Nakada, K1
Tsukamoto, E1
Furudate, M1
Sugihara, H1
Hoshi, M1
Cohen, MB1
Saxton, RE1
Lake, RR1
Cagle, L1
Graham, LS1
Nizze, A1
Yamada, LS1
Gan, M1
Bronca, G1
Greenwell, K1
Muranaka, A2
Tabuchi, A1
Mitsumori, M1
Kawada, M1
Liewendahl, K1
Kairento, AL1
Pyrhönen, S1
Franssila, K1
Asko-Seljavaara, S1
Lindroth, L1
Virkkunen, P1
Launes, J1
Wada, M1
Ichiya, Y1
Katsuragi, M1
Kuwabara, Y1
Ayabe, Z1
Matsuura, K1
Takeshita, Y1

Trials

1 trial available for iofetamine and Melanoma

ArticleYear
Low efficacy of 18F-FDG PET for detection of uveal malignant melanoma compared with 123I-IMP SPECT.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:3

    Topics: Adult; Aged; Female; Fluorodeoxyglucose F18; Humans; Iofetamine; Male; Melanoma; Middle Aged; Positr

2006

Other Studies

31 other studies available for iofetamine and Melanoma

ArticleYear
Assessment of SPECT-CT fusion images and semi-quantitative evaluation using SUV in
    Annals of nuclear medicine, 2020, Volume: 34, Issue:11

    Topics: Adult; Aged; Biological Transport; Choroid Neoplasms; Female; Humans; Iofetamine; Male; Melanoma; Mi

2020
A case of iris melanocytoma transformed to malignant melanoma.
    Japanese journal of ophthalmology, 2009, Volume: 53, Issue:3

    Topics: Cell Transformation, Neoplastic; Eye Enucleation; Humans; Iofetamine; Iris Neoplasms; Magnetic Reson

2009
Malignant melanoma of the breast: N-isopropyl-p-(123) I-iodoamphetamine single photon emission computed tomography ((123) I-IMP SPECT) is useful for the detection of metastasis.
    The Journal of dermatology, 2010, Volume: 37, Issue:9

    Topics: Adrenal Gland Neoplasms; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brai

2010
Diagnosis of uveal malignant melanoma by a new semiquantitative assessment of N-isopropyl-p-[123I]-iodoamphetamine.
    Japanese journal of ophthalmology, 2011, Volume: 55, Issue:2

    Topics: Aged; Choroid Neoplasms; Diagnosis, Computer-Assisted; Female; Humans; Imaging, Three-Dimensional; I

2011
A case of metastatic choroidal tumor simulating a choroidal melanoma.
    Japanese journal of ophthalmology, 2011, Volume: 55, Issue:3

    Topics: Adenocarcinoma; Adult; Cell Proliferation; Choroid Neoplasms; Diagnosis, Differential; Eye Enucleati

2011
Successful scintigraphic visualization of metastatic lesions of a hard palate melanoma with N-isopropyl-p-[123I]-iodoamphetamine.
    International journal of dermatology, 2003, Volume: 42, Issue:4

    Topics: Aged; Head and Neck Neoplasms; Humans; Iofetamine; Male; Melanoma; Mouth Neoplasms; Radionuclide Ima

2003
Rectal malignant melanoma diagnosed by N-isopropyl- p-123I-iodoamphetamine single photon emission computed tomography and 5-S-cysteinyl dopa: report of a case.
    Surgery today, 2003, Volume: 33, Issue:6

    Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Dihydroxyphenylalanine; Female; Humans; Iofetamine; Mela

2003
Comparison of I-123 IMP and Ga-67 citrate scintigraphy of malignant melanoma.
    Clinical nuclear medicine, 2003, Volume: 28, Issue:8

    Topics: Aged; Citrates; Female; Gallium; Humans; Iofetamine; Male; Melanoma; Middle Aged; Postoperative Care

2003
What is the diagnosis? Uveal malignant melanoma.
    Annals of nuclear medicine, 2003, Volume: 17, Issue:7

    Topics: Aged; Humans; Iofetamine; Melanoma; Radionuclide Imaging; Radiopharmaceuticals; Uveal Neoplasms; Vis

2003
Clinical efficacy of 123I-IMP SPECT for the diagnosis of malignant uveal melanoma.
    International journal of clinical oncology, 2004, Volume: 9, Issue:2

    Topics: Aged; Female; Humans; Iofetamine; Male; Melanoma; Middle Aged; Radiopharmaceuticals; Tomography, Emi

2004
Clinical role of 123I-IMP SPECT for the differential diagnosis of ocular malignant melanoma: a time-course analysis.
    Nuclear medicine communications, 2007, Volume: 28, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Diagnosis, Differential; Eye Neoplasms; Female; H

2007
Characterization of an orbital melanoma and mucosa associated lymphoid tissue (MALT) lymphoma by dual phase N-isopropyl-p-I-123 iodoamphetamine.
    Clinical nuclear medicine, 2007, Volume: 32, Issue:8

    Topics: Aged; Choroid Neoplasms; Female; Humans; Iofetamine; Lacrimal Apparatus Diseases; Lymphoma, B-Cell,

2007
The relationship of the eye uptake of N-isopropyl-p-[123I]iodoamphetamine to melanin production.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1984, Volume: 25, Issue:3

    Topics: Amphetamines; Animals; Brain; Cells, Cultured; Eye; Humans; Iodine Radioisotopes; Iofetamine; Kineti

1984
[A case of intracranial malignant melanoma with increased uptake of IMP in SPECT].
    Kaku igaku. The Japanese journal of nuclear medicine, 1993, Volume: 30, Issue:11

    Topics: Adult; Amphetamines; Brain Neoplasms; Humans; Iodine Radioisotopes; Iofetamine; Male; Melanoma; Tomo

1993
Scintigraphic study of malignant melanoma with 123I-iodoamphetamine.
    Nuclear medicine communications, 1996, Volume: 17, Issue:2

    Topics: Aged; Aged, 80 and over; Amphetamines; Female; Humans; Iofetamine; Lung Neoplasms; Male; Melanoma; M

1996
[Oligomelanotic malignant melanoma in the nasal cavity diagnosed by IMP scintigraphy].
    Kaku igaku. The Japanese journal of nuclear medicine, 1997, Volume: 34, Issue:9

    Topics: Aged; Aged, 80 and over; Amphetamines; Diagnosis, Differential; Female; Gallium Radioisotopes; Human

1997
[A case of choroidal malignant melanoma in which 123I-IMP scintigraphy was useful for diagnosis].
    Kaku igaku. The Japanese journal of nuclear medicine, 1998, Volume: 35, Issue:6

    Topics: Choroid Neoplasms; Humans; Iodine Radioisotopes; Iofetamine; Male; Melanoma; Middle Aged; Radionucli

1998
Efficacy of (123)N-isopropyl-p-[(123)I]-iodoamphetamine single photon emission computed tomography for the diagnosis of uveal malignant melanoma.
    American journal of ophthalmology, 2001, Volume: 132, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Conjunctival Neoplasms; Eyelid Neoplasms; Female; Humans; Iofetamine

2001
[Primary intracranial melanoma: a case report].
    No shinkei geka. Neurological surgery, 1992, Volume: 20, Issue:11

    Topics: Adult; Amphetamines; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Dacarba

1992
Ocular melanoma: detection using iodine-123-iodoamphetamine and SPECT imaging.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1990, Volume: 31, Issue:3

    Topics: Amphetamines; Choroid Neoplasms; Humans; Iodine Radioisotopes; Iofetamine; Male; Melanoma; Middle Ag

1990
[123I-N-isopropyl-p-iodoamphetamine scintigraphy in patients with malignant melanoma].
    Radioisotopes, 1990, Volume: 39, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amphetamines; Female; Humans; Iodine Radioisotopes; Iofetamine; Male

1990
Detection of human malignant melanoma with gallium-67 citrate and N-isopropyl-(I-123) p-iodo-amphetamine.
    The Kurume medical journal, 1989, Volume: 36, Issue:4

    Topics: Aged; Amphetamines; Citrates; Citric Acid; Head and Neck Neoplasms; Heel; Humans; Iofetamine; Lympha

1989
Increased iofetamine I 123 brain uptake in metastatic melanoma.
    Archives of neurology, 1988, Volume: 45, Issue:10

    Topics: Amphetamines; Brain; Brain Neoplasms; Carcinoma, Small Cell; Humans; Iodine Radioisotopes; Iofetamin

1988
[Scintigraphy using N-isopropyl-p-[123I]-iodoamphetamine in malignant melanoma].
    Kaku igaku. The Japanese journal of nuclear medicine, 1988, Volume: 25, Issue:10

    Topics: Aged; Aged, 80 and over; Amphetamines; Female; Humans; Iodine Radioisotopes; Iofetamine; Male; Melan

1988
[Visualization of bone marrow with N-isopropyl-p-[123I]-iodoamphetamine in a case of malignant melanoma].
    Kaku igaku. The Japanese journal of nuclear medicine, 1988, Volume: 25, Issue:10

    Topics: Aged; Amphetamines; Bone Marrow; Humans; Iodine Radioisotopes; Iofetamine; Male; Maxillary Sinus Neo

1988
[The comparative study with Ga-67 and I-123 IMP in malignant melanoma].
    Kaku igaku. The Japanese journal of nuclear medicine, 1988, Volume: 25, Issue:12

    Topics: Adult; Aged; Amphetamines; Female; Follow-Up Studies; Gallium Radioisotopes; Humans; Iofetamine; Lun

1988
Detection of malignant melanoma with iodine-123 iodoamphetamine.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1988, Volume: 29, Issue:7

    Topics: Adult; Aged; Amphetamines; Female; Humans; Iodine Radioisotopes; Iofetamine; Male; Melanoma; Middle

1988
Visualization of ocular melanoma with N-isopropyl-p-[123I]-iodoamphetamine.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1988, Volume: 29, Issue:8

    Topics: Amphetamines; Eye; Eye Neoplasms; Humans; Iodine Radioisotopes; Iofetamine; Male; Melanoma; Middle A

1988
[Visualization of a lung metastatic lesion from malignant melanoma by N-isopropyl-p-123I-iodoamphetamine: usefulness of L-dopa load scintigraphy].
    Kaku igaku. The Japanese journal of nuclear medicine, 1987, Volume: 24, Issue:7

    Topics: Aged; Amphetamines; Female; Humans; Iofetamine; Levodopa; Lung Neoplasms; Melanoma; Nose Neoplasms;

1987
Localization of melanoma with radiolabelled monoclonal antibody fragments and iodoamphetamine.
    European journal of nuclear medicine, 1986, Volume: 12, Issue:7

    Topics: Adult; Amphetamines; Antibodies, Monoclonal; Female; Humans; Iodine Radioisotopes; Iofetamine; Male;

1986
Scintigraphic visualization of human malignant melanoma with N-isopropyl-P-[I-123] iodoamphetamine.
    Clinical nuclear medicine, 1985, Volume: 10, Issue:6

    Topics: Adult; Amphetamines; Humans; Iodine Radioisotopes; Iofetamine; Male; Melanoma; Radionuclide Imaging;

1985